ATE423135T1 - Heterodimere peptide mit ngf aktivität und deren verwendung zur behandlung von neurodegenerativen krankheiten - Google Patents

Heterodimere peptide mit ngf aktivität und deren verwendung zur behandlung von neurodegenerativen krankheiten

Info

Publication number
ATE423135T1
ATE423135T1 AT05012643T AT05012643T ATE423135T1 AT E423135 T1 ATE423135 T1 AT E423135T1 AT 05012643 T AT05012643 T AT 05012643T AT 05012643 T AT05012643 T AT 05012643T AT E423135 T1 ATE423135 T1 AT E423135T1
Authority
AT
Austria
Prior art keywords
treatment
neurodegenerative diseases
loop
ngf
ngf activity
Prior art date
Application number
AT05012643T
Other languages
English (en)
Inventor
Luigi Vitagliano
Laura Zaccaro
Giancarlo Morelli
Enzo Martegani
Original Assignee
Primm Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Primm Srl filed Critical Primm Srl
Application granted granted Critical
Publication of ATE423135T1 publication Critical patent/ATE423135T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT05012643T 2005-06-13 2005-06-13 Heterodimere peptide mit ngf aktivität und deren verwendung zur behandlung von neurodegenerativen krankheiten ATE423135T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05012643A EP1734052B1 (de) 2005-06-13 2005-06-13 Heterodimere Peptide mit NGF Aktivität und deren Verwendung zur Behandlung von neurodegenerativen Krankheiten

Publications (1)

Publication Number Publication Date
ATE423135T1 true ATE423135T1 (de) 2009-03-15

Family

ID=35276556

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05012643T ATE423135T1 (de) 2005-06-13 2005-06-13 Heterodimere peptide mit ngf aktivität und deren verwendung zur behandlung von neurodegenerativen krankheiten

Country Status (5)

Country Link
US (1) US8461110B2 (de)
EP (2) EP1734052B1 (de)
AT (1) ATE423135T1 (de)
DE (1) DE602005012812D1 (de)
WO (1) WO2006133853A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006318550A1 (en) * 2005-11-22 2007-05-31 Mcgill University Intraocular pressure-regulated early genes and uses thereof
EP1921087A1 (de) * 2006-11-10 2008-05-14 Primm S.R.L. Verfahren zur Herstellung von cyclischen Peptiden
WO2008070513A1 (en) * 2006-12-01 2008-06-12 Alcon Research, Ltd. Modulation of polysialylated neural adhesion molecules (psa-ncam) as a regulator of ocular disease
WO2008070132A2 (en) * 2006-12-05 2008-06-12 The Royal Institution For The Advancement Of Learning/ Mcgill University Methods of use of trk receptor modulators
ITRM20070119A1 (it) * 2007-03-08 2008-09-09 Inbios S R L Udo del ngf per la preparazione di mendicamenti per la cura della gliosi reattiva
JP2011506582A (ja) * 2007-12-20 2011-03-03 サイトス バイオテクノロジー アーゲー 神経成長因子コンジュゲート及びその使用
KR101565185B1 (ko) * 2008-04-04 2015-11-02 미메토젠 파르마슈티칼스 인크. 건안증을 치료하기 위한 베타-턴 펩티도미메틱 환상 화합물
JP5663498B2 (ja) 2009-02-27 2015-02-04 ミメトゲン ファーマシュウティカルズ インコーポレイテッドＭｉｍｅｔｏｇｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 網膜色素変性症を処置するためのペプチド模倣環状化合物
US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
US9067988B2 (en) 2010-12-01 2015-06-30 Alderbio Holdings Llc Methods of preventing or treating pain using anti-NGF antibodies
US9884909B2 (en) 2010-12-01 2018-02-06 Alderbio Holdings Llc Anti-NGF compositions and use thereof
KR20190112175A (ko) 2010-12-01 2019-10-02 앨더바이오 홀딩스 엘엘씨 항―ｎｇｆ 조성물 및 그의 용도
US9539324B2 (en) 2010-12-01 2017-01-10 Alderbio Holdings, Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
US9078878B2 (en) 2010-12-01 2015-07-14 Alderbio Holdings Llc Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
JP6248103B2 (ja) * 2012-06-22 2017-12-13 ミメトゲン ファーマシュウティカルズ インコーポレイテッドＭｉｍｅｔｏｇｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． β−ターン環式ペプチド模倣化合物の合成

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9402331D0 (en) * 1994-02-07 1994-03-30 Univ Mcgill Nerve growth factor structural analogs and their uses
US5958875A (en) * 1996-03-29 1999-09-28 The Regents Of The University Of California Synthetic peptides derivatives with nerve growth factor-like neurotrophic activity

Also Published As

Publication number Publication date
EP1734052B1 (de) 2009-02-18
US8461110B2 (en) 2013-06-11
EP1891099A1 (de) 2008-02-27
US20090318335A1 (en) 2009-12-24
EP1734052A1 (de) 2006-12-20
DE602005012812D1 (de) 2009-04-02
WO2006133853A1 (en) 2006-12-21

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