AR076977A1 - Proteinas precursoras repetitivas autoensambladas - Google Patents

Proteinas precursoras repetitivas autoensambladas

Info

Publication number
AR076977A1
AR076977A1 ARP100101974A ARP100101974A AR076977A1 AR 076977 A1 AR076977 A1 AR 076977A1 AR P100101974 A ARP100101974 A AR P100101974A AR P100101974 A ARP100101974 A AR P100101974A AR 076977 A1 AR076977 A1 AR 076977A1
Authority
AR
Argentina
Prior art keywords
elements
aux
pep
acid sequences
self
Prior art date
Application number
ARP100101974A
Other languages
English (en)
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of AR076977A1 publication Critical patent/AR076977A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Secuencias de ácidos nucleicos y constructos de expresion que los codifican, y métodos para la produccion recombinante de péptidos mediante el uso de dichas proteínas precursoras. Reivindicacion 1: Una proteína precursora caracterizada porque comprende una secuencia repetitiva, que puede ser escindida de los elementos de péptido deseado (Pep) y los elementos de péptido auxiliar (Aux) de la formula general: (Pep-Aux)x o (Aux-Pep)x donde x >1, en donde los elementos Aux son idénticos o diferentes y comprenden elementos de secuencias de aminoácidos que imparten a dicha proteína precursora propiedades de autoensamblaje; y los elementos Pep son idénticos o diferentes y comprenden las secuencias de aminoácidos de moléculas peptidicas idénticas o diferentes.
ARP100101974A 2009-06-03 2010-06-03 Proteinas precursoras repetitivas autoensambladas AR076977A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09161837 2009-06-03

Publications (1)

Publication Number Publication Date
AR076977A1 true AR076977A1 (es) 2011-07-20

Family

ID=43298234

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100101974A AR076977A1 (es) 2009-06-03 2010-06-03 Proteinas precursoras repetitivas autoensambladas

Country Status (20)

Country Link
US (1) US9481719B2 (es)
EP (1) EP2437769B1 (es)
JP (1) JP5730293B2 (es)
KR (2) KR101812842B1 (es)
CN (1) CN102724992B (es)
AR (1) AR076977A1 (es)
AU (1) AU2010255732B8 (es)
BR (1) BRPI1011144B8 (es)
CA (1) CA2763626A1 (es)
CL (1) CL2011003075A1 (es)
CR (1) CR20110619A (es)
EC (1) ECSP12011577A (es)
ES (1) ES2763168T3 (es)
IL (1) IL216619A0 (es)
MX (1) MX2011012906A (es)
NZ (2) NZ596735A (es)
PE (1) PE20121033A1 (es)
RU (1) RU2548815C2 (es)
TW (1) TWI429750B (es)
WO (1) WO2010139736A2 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008531506A (ja) * 2005-02-24 2008-08-14 ザ ユニバーシティー オブ クイーンズランド ペプチドネットワーク
US20150031600A1 (en) * 2010-12-14 2015-01-29 The University Of Queensland Designed biosurfactants, their manufacture, purification and use
CN103740661B (zh) * 2012-05-10 2015-06-03 江南大学 一种提高酶热稳定性的方法
CN103740662B (zh) * 2012-05-10 2015-08-19 江南大学 一种提高酶热稳定性的方法
CN103740659B (zh) * 2012-05-10 2015-06-03 江南大学 一种提高酶热稳定性的方法
US9976133B2 (en) 2012-06-20 2018-05-22 The Regents Of The University Of California Synzymes
CN104755502B (zh) * 2012-10-12 2018-05-18 清华大学 多肽的产生和纯化方法
WO2017055587A1 (de) * 2015-10-01 2017-04-06 Basf Se Rekombinante herstellung von peptiden
KR101976923B1 (ko) * 2017-05-10 2019-05-10 건국대학교 산학협력단 D-루이신 치환을 통해 항균 효과를 증진시킨 항생 펩타이드 및 이의 용도
KR101970876B1 (ko) * 2017-05-10 2019-04-19 건국대학교 산학협력단 D-라이신 치환을 통해 항균 효과를 증진시킨 항생 펩타이드 및 이의 용도
KR101970875B1 (ko) * 2017-05-10 2019-04-19 건국대학교 산학협력단 글루탐산 치환을 통해 항균 효과를 증진시킨 항생 펩타이드 및 이의 용도
CN106496307B (zh) * 2016-11-09 2019-11-01 湖南科技学院 一种新的抗菌肽及其用途
WO2018157773A1 (zh) 2017-02-28 2018-09-07 暨南大学 一种促进创伤后组织修复与再生的修复肽及其应用
CN108503690B (zh) * 2017-02-28 2020-07-03 暨南大学 一种促进创伤后组织修复与再生的修复肽及其应用
WO2020048996A1 (en) 2018-09-06 2020-03-12 ETH Zürich Self-assembling globular proteins and uses thereof
CN111388374B (zh) * 2020-04-11 2022-09-06 百草堂(湖北)制药有限公司 一种洗发露
CN116874613B (zh) * 2023-09-06 2023-11-17 南京华盖制药有限公司 一种广谱高效的抗菌多肽aph143及其制备方法和应用

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GB9504761D0 (en) 1995-03-09 1995-04-26 Unilever Plc Amphiphilic peptide and analogs thereof
KR100263583B1 (ko) * 1997-05-28 2000-08-01 박종헌 항균 펩타이드의 대량 제조방법 및 그에 유용한 플라즈미드 벡타
CA2351737A1 (en) * 1998-11-20 2000-06-02 Micrologix Biotech Inc. Efficient methods for producing antimicrobial cationic peptides in host cells
WO2002099082A2 (en) * 2001-06-06 2002-12-12 University Of Wyoming Expression of spider silk proteins in higher plants
KR100438416B1 (ko) 2001-09-19 2004-07-02 학교법인조선대학교 Ｃａ－ｍａ 펩타이드의 아미노산 중 하나 또는 그 이상을치환하여 ＋ 전극과 소수성 영역이 증가된 신규한펩타이드 및 그를 포함하는 약학적 조성물
NZ532962A (en) 2001-11-20 2006-11-30 Novozymes As Antimicrobial polypeptides from pseudoplectania nigrella
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KR20050016362A (ko) 2002-04-22 2005-02-21 다우 글로벌 테크놀로지스 인크. 펩티드의 저비용 생산
EP2471527A3 (en) 2003-03-17 2012-12-12 The Trustees Of The University Of Pennsylvania Facially amphiphillc polymers and oligomers and uses thereof
EP2520584A1 (en) 2004-07-22 2012-11-07 AMSilk GmbH Recombinant spider silk proteins
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WO2009014782A2 (en) * 2007-04-27 2009-01-29 Dow Global Technologies Inc. Improved production and in vivo assembly of soluble recombinant icosahedral virus-like particles
JP5743542B2 (ja) 2007-06-20 2015-07-01 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 合成反復タンパク質、その製造および使用
CN101903011B (zh) * 2007-12-21 2014-08-06 巴斯夫欧洲公司 含肽的抗头皮屑组合物

Also Published As

Publication number Publication date
BRPI1011144B1 (pt) 2021-02-02
CA2763626A1 (en) 2010-12-09
RU2548815C2 (ru) 2015-04-20
TW201103981A (en) 2011-02-01
KR20120014940A (ko) 2012-02-20
AU2010255732A8 (en) 2014-03-13
EP2437769B1 (de) 2019-09-25
US9481719B2 (en) 2016-11-01
TWI429750B (zh) 2014-03-11
US20120088268A1 (en) 2012-04-12
IL216619A0 (en) 2012-02-29
AU2010255732B8 (en) 2014-03-13
KR101834018B1 (ko) 2018-03-05
CN102724992B (zh) 2016-05-18
JP2012528579A (ja) 2012-11-15
JP5730293B2 (ja) 2015-06-10
AU2010255732A1 (en) 2011-12-22
KR101812842B1 (ko) 2017-12-27
KR20140127344A (ko) 2014-11-03
CL2011003075A1 (es) 2012-06-29
NZ596735A (en) 2013-10-25
ES2763168T3 (es) 2020-05-27
WO2010139736A2 (de) 2010-12-09
ECSP12011577A (es) 2012-02-29
EP2437769A2 (de) 2012-04-11
BRPI1011144B8 (pt) 2021-05-25
CR20110619A (es) 2012-02-09
MX2011012906A (es) 2012-02-01
PE20121033A1 (es) 2012-08-02
WO2010139736A3 (de) 2011-03-10
BRPI1011144A2 (pt) 2016-10-25
NZ615847A (en) 2014-11-28
CN102724992A (zh) 2012-10-10
AU2010255732B2 (en) 2013-09-12
RU2011153757A (ru) 2013-07-20

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