AR076977A1 - Proteinas precursoras repetitivas autoensambladas - Google Patents
Proteinas precursoras repetitivas autoensambladasInfo
- Publication number
- AR076977A1 AR076977A1 ARP100101974A ARP100101974A AR076977A1 AR 076977 A1 AR076977 A1 AR 076977A1 AR P100101974 A ARP100101974 A AR P100101974A AR P100101974 A ARP100101974 A AR P100101974A AR 076977 A1 AR076977 A1 AR 076977A1
- Authority
- AR
- Argentina
- Prior art keywords
- elements
- aux
- pep
- acid sequences
- self
- Prior art date
Links
- 239000002243 precursor Substances 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 230000003252 repetitive effect Effects 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 238000001338 self-assembly Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Secuencias de ácidos nucleicos y constructos de expresion que los codifican, y métodos para la produccion recombinante de péptidos mediante el uso de dichas proteínas precursoras. Reivindicacion 1: Una proteína precursora caracterizada porque comprende una secuencia repetitiva, que puede ser escindida de los elementos de péptido deseado (Pep) y los elementos de péptido auxiliar (Aux) de la formula general: (Pep-Aux)x o (Aux-Pep)x donde x >1, en donde los elementos Aux son idénticos o diferentes y comprenden elementos de secuencias de aminoácidos que imparten a dicha proteína precursora propiedades de autoensamblaje; y los elementos Pep son idénticos o diferentes y comprenden las secuencias de aminoácidos de moléculas peptidicas idénticas o diferentes.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09161837 | 2009-06-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR076977A1 true AR076977A1 (es) | 2011-07-20 |
Family
ID=43298234
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100101974A AR076977A1 (es) | 2009-06-03 | 2010-06-03 | Proteinas precursoras repetitivas autoensambladas |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9481719B2 (es) |
| EP (1) | EP2437769B1 (es) |
| JP (1) | JP5730293B2 (es) |
| KR (2) | KR101834018B1 (es) |
| CN (1) | CN102724992B (es) |
| AR (1) | AR076977A1 (es) |
| AU (1) | AU2010255732B8 (es) |
| BR (1) | BRPI1011144B8 (es) |
| CA (1) | CA2763626A1 (es) |
| CL (1) | CL2011003075A1 (es) |
| CR (1) | CR20110619A (es) |
| EC (1) | ECSP12011577A (es) |
| ES (1) | ES2763168T3 (es) |
| IL (1) | IL216619A0 (es) |
| MX (1) | MX2011012906A (es) |
| NZ (2) | NZ615847A (es) |
| PE (1) | PE20121033A1 (es) |
| RU (1) | RU2548815C2 (es) |
| TW (1) | TWI429750B (es) |
| WO (1) | WO2010139736A2 (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006089364A1 (en) * | 2005-02-24 | 2006-08-31 | The University Of Queensland | Peptide networks |
| WO2012079125A1 (en) * | 2010-12-14 | 2012-06-21 | The University Of Queensland | Designed biosurfactants, their manufacture, purification and use |
| CN103740662B (zh) * | 2012-05-10 | 2015-08-19 | 江南大学 | 一种提高酶热稳定性的方法 |
| CN103740659B (zh) * | 2012-05-10 | 2015-06-03 | 江南大学 | 一种提高酶热稳定性的方法 |
| CN103740661B (zh) * | 2012-05-10 | 2015-06-03 | 江南大学 | 一种提高酶热稳定性的方法 |
| EP2864349A4 (en) | 2012-06-20 | 2016-02-24 | Univ California | DYNAMIC BIOMIMETIC SYNZYM CATALYST, CATALYSIS AND CATALYST SYSTEMS |
| CN104755502B (zh) * | 2012-10-12 | 2018-05-18 | 清华大学 | 多肽的产生和纯化方法 |
| WO2017055587A1 (de) * | 2015-10-01 | 2017-04-06 | Basf Se | Rekombinante herstellung von peptiden |
| KR101970875B1 (ko) * | 2017-05-10 | 2019-04-19 | 건국대학교 산학협력단 | 글루탐산 치환을 통해 항균 효과를 증진시킨 항생 펩타이드 및 이의 용도 |
| KR101976923B1 (ko) * | 2017-05-10 | 2019-05-10 | 건국대학교 산학협력단 | D-루이신 치환을 통해 항균 효과를 증진시킨 항생 펩타이드 및 이의 용도 |
| KR101970876B1 (ko) * | 2017-05-10 | 2019-04-19 | 건국대학교 산학협력단 | D-라이신 치환을 통해 항균 효과를 증진시킨 항생 펩타이드 및 이의 용도 |
| CN106496307B (zh) * | 2016-11-09 | 2019-11-01 | 湖南科技学院 | 一种新的抗菌肽及其用途 |
| US11260101B2 (en) | 2017-02-28 | 2022-03-01 | Jinan University | Repair peptide for use in promoting post-traumatic tissue repair and regeneration, and application thereof |
| CN108503690B (zh) * | 2017-02-28 | 2020-07-03 | 暨南大学 | 一种促进创伤后组织修复与再生的修复肽及其应用 |
| WO2020048996A1 (en) | 2018-09-06 | 2020-03-12 | ETH Zürich | Self-assembling globular proteins and uses thereof |
| CN111388374B (zh) * | 2020-04-11 | 2022-09-06 | 百草堂(湖北)制药有限公司 | 一种洗发露 |
| CN116874613B (zh) * | 2023-09-06 | 2023-11-17 | 南京华盖制药有限公司 | 一种广谱高效的抗菌多肽aph143及其制备方法和应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9504761D0 (en) | 1995-03-09 | 1995-04-26 | Unilever Plc | Amphiphilic peptide and analogs thereof |
| KR100263583B1 (ko) * | 1997-05-28 | 2000-08-01 | 박종헌 | 항균 펩타이드의 대량 제조방법 및 그에 유용한 플라즈미드 벡타 |
| WO2000031279A2 (en) * | 1998-11-20 | 2000-06-02 | Micrologix Biotech Inc. | Producing antimicrobial cationic peptides as fusion proteins |
| WO2002099082A2 (en) * | 2001-06-06 | 2002-12-12 | University Of Wyoming | Expression of spider silk proteins in higher plants |
| KR100438416B1 (ko) | 2001-09-19 | 2004-07-02 | 학교법인조선대학교 | Ｃａ－ｍａ 펩타이드의 아미노산 중 하나 또는 그 이상을치환하여 ＋ 전극과 소수성 영역이 증가된 신규한펩타이드 및 그를 포함하는 약학적 조성물 |
| HU227387B1 (en) | 2001-11-20 | 2011-05-30 | Novozymes Adenium Biotech As | Antimicrobial polypeptides from pseudoplectania nigrella |
| US20030219854A1 (en) | 2002-03-21 | 2003-11-27 | Micrologix Biotech Inc. | Methods for producing modified anti-infective peptides |
| WO2003089455A2 (en) * | 2002-04-22 | 2003-10-30 | Dow Global Technologies Inc. | Low-cost production of peptides |
| EP2471527A3 (en) | 2003-03-17 | 2012-12-12 | The Trustees Of The University Of Pennsylvania | Facially amphiphillc polymers and oligomers and uses thereof |
| AU2005263622B2 (en) * | 2004-07-22 | 2012-04-26 | Amsilk Gmbh | Recombinant spider silk proteins |
| WO2007025719A1 (en) | 2005-08-29 | 2007-03-08 | Technische Universitaet Muenchen | Modified spider silk proteins |
| US7709227B2 (en) | 2006-01-04 | 2010-05-04 | Phasebio Pharmaceuticals, Inc. | Multimeric ELP fusion constructs |
| EP1978937A1 (de) | 2006-01-20 | 2008-10-15 | Basf Se | Verwendung von amphiphilen selbstassemblierenden proteinen zur formulierung von schwer wasserlöslichen effektstoffen |
| EP2139993A2 (en) * | 2007-04-27 | 2010-01-06 | Dow Global Technologies Inc. | Improved production and in vivo assembly of soluble recombinant icosahedral virus-like particles |
| ES2530190T3 (es) | 2007-06-20 | 2015-02-27 | Basf Se | Proteínas repetitivas sintéticas, su producción y su uso |
| CA2708554C (en) * | 2007-12-21 | 2014-04-22 | Basf Se | Anti-dandruff compositions containing peptides |
-
2010
- 2010-06-02 MX MX2011012906A patent/MX2011012906A/es active IP Right Grant
- 2010-06-02 PE PE2011002049A patent/PE20121033A1/es not_active Application Discontinuation
- 2010-06-02 BR BRPI1011144A patent/BRPI1011144B8/pt not_active IP Right Cessation
- 2010-06-02 ES ES10724472T patent/ES2763168T3/es active Active
- 2010-06-02 EP EP10724472.5A patent/EP2437769B1/de active Active
- 2010-06-02 CN CN201080033646.XA patent/CN102724992B/zh not_active Expired - Fee Related
- 2010-06-02 WO PCT/EP2010/057726 patent/WO2010139736A2/de active Application Filing
- 2010-06-02 KR KR1020127000053A patent/KR101834018B1/ko active IP Right Grant
- 2010-06-02 JP JP2012513614A patent/JP5730293B2/ja not_active Expired - Fee Related
- 2010-06-02 NZ NZ615847A patent/NZ615847A/en not_active IP Right Cessation
- 2010-06-02 AU AU2010255732A patent/AU2010255732B8/en not_active Ceased
- 2010-06-02 CA CA2763626A patent/CA2763626A1/en not_active Abandoned
- 2010-06-02 RU RU2011153757/10A patent/RU2548815C2/ru not_active IP Right Cessation
- 2010-06-02 NZ NZ596735A patent/NZ596735A/xx not_active IP Right Cessation
- 2010-06-02 KR KR1020147026327A patent/KR101812842B1/ko active IP Right Grant
- 2010-06-02 US US13/375,559 patent/US9481719B2/en active Active
- 2010-06-03 TW TW099117988A patent/TWI429750B/zh not_active IP Right Cessation
- 2010-06-03 AR ARP100101974A patent/AR076977A1/es unknown
-
2011
- 2011-11-23 CR CR20110619A patent/CR20110619A/es unknown
- 2011-11-27 IL IL216619A patent/IL216619A0/en unknown
- 2011-12-02 CL CL2011003075A patent/CL2011003075A1/es unknown
-
2012
- 2012-01-06 EC EC2012011577A patent/ECSP12011577A/es unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |