|
US8981061B2
(en)
|
2001-03-20 |
2015-03-17 |
Novo Nordisk A/S |
Receptor TREM (triggering receptor expressed on myeloid cells) and uses thereof
|
|
GB0426146D0
(en)
|
2004-11-29 |
2004-12-29 |
Bioxell Spa |
Therapeutic peptides and method
|
|
US7904394B2
(en)
*
|
2007-05-16 |
2011-03-08 |
Lynch Marks, LLC |
Documenting mail work flow
|
|
ES2622460T3
(es)
|
2007-09-26 |
2017-07-06 |
Ucb Biopharma Sprl |
Fusiones de anticuerpos con doble especificidad
|
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
|
US8557243B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
EFGR antibodies comprising modular recognition domains
|
|
US8574577B2
(en)
|
2008-01-03 |
2013-11-05 |
The Scripps Research Institute |
VEGF antibodies comprising modular recognition domains
|
|
US8454960B2
(en)
|
2008-01-03 |
2013-06-04 |
The Scripps Research Institute |
Multispecific antibody targeting and multivalency through modular recognition domains
|
|
US8557242B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
ERBB2 antibodies comprising modular recognition domains
|
|
EA201500156A3
(ru)
|
2008-01-03 |
2017-09-29 |
Дзе Скриппс Рисерч Инститьют |
Доставка антител посредством модульного домена распознавания
|
|
US20100260668A1
(en)
*
|
2008-04-29 |
2010-10-14 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
|
EP2282769A4
(en)
*
|
2008-04-29 |
2012-04-25 |
Abbott Lab |
DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND ITS USES
|
|
KR20110016959A
(ko)
|
2008-06-03 |
2011-02-18 |
아보트 러보러터리즈 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
NZ589434A
(en)
|
2008-06-03 |
2012-11-30 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
NZ603698A
(en)
*
|
2008-07-08 |
2014-03-28 |
Abbvie Inc |
Prostaglandin e2 dual variable domain immunoglobulins and uses thereof
|
|
SI2334705T1
(sl)
|
2008-09-26 |
2017-05-31 |
Ucb Biopharma Sprl |
Biološki produkti
|
|
CN108530543B
(zh)
|
2009-02-03 |
2023-06-23 |
阿穆尼克斯制药公司 |
延伸重组多肽和包含该延伸重组多肽的组合物
|
|
US8734796B2
(en)
|
2009-03-20 |
2014-05-27 |
Amgen Inc. |
Carrier immunoglobulins
|
|
AU2010230563A1
(en)
|
2009-04-02 |
2011-09-22 |
Roche Glycart Ag |
Multispecific antibodies comprising full length antibodies and single chain Fab fragments
|
|
US20100256340A1
(en)
|
2009-04-07 |
2010-10-07 |
Ulrich Brinkmann |
Trivalent, bispecific antibodies
|
|
EP2417164A1
(en)
*
|
2009-04-07 |
2012-02-15 |
Roche Glycart AG |
Bispecific anti-erbb-2/anti-c-met antibodies
|
|
RU2570633C2
(ru)
*
|
2009-05-27 |
2015-12-10 |
Ф.Хоффманн-Ля Рош Аг |
Три- или тетраспецифические антитела
|
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
|
US20120270797A1
(en)
*
|
2009-08-13 |
2012-10-25 |
Massachusetts Institute Of Technology |
Engineered proteins including mutant fibronectin domains
|
|
CN102612524A
(zh)
*
|
2009-09-01 |
2012-07-25 |
雅培制药有限公司 |
双重可变结构域免疫球蛋白及其用途
|
|
US20120283415A1
(en)
|
2009-09-10 |
2012-11-08 |
Ucb Pharma S.A. |
Multivalent Antibodies
|
|
WO2011034605A2
(en)
|
2009-09-16 |
2011-03-24 |
Genentech, Inc. |
Coiled coil and/or tether containing protein complexes and uses thereof
|
|
AU2010306774A1
(en)
*
|
2009-10-14 |
2012-05-03 |
Merrimack Pharmaceuticals, Inc. |
Bispecific binding agents targeting IGF-1R and ErbB3 signalling and uses thereof
|
|
TW201119676A
(en)
*
|
2009-10-15 |
2011-06-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
UY32979A
(es)
*
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
WO2011060144A2
(en)
*
|
2009-11-11 |
2011-05-19 |
Virginia Tech Intellectual Properties, Inc. |
Compositions and methods to protect cells by blocking entry of pathogen proteins
|
|
GB0920127D0
(en)
*
|
2009-11-17 |
2009-12-30 |
Ucb Pharma Sa |
Antibodies
|
|
GB0920324D0
(en)
*
|
2009-11-19 |
2010-01-06 |
Ucb Pharma Sa |
Antibodies
|
|
EP2332994A1
(en)
*
|
2009-12-09 |
2011-06-15 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Trispecific therapeutics against acute myeloid leukaemia
|
|
GB201000467D0
(en)
*
|
2010-01-12 |
2010-02-24 |
Ucb Pharma Sa |
Antibodies
|
|
KR20130056855A
(ko)
|
2010-03-01 |
2013-05-30 |
카리스 라이프 사이언스 룩셈부르크 홀딩스 |
치료진단용 생물학적 지표들
|
|
TR201903279T4
(tr)
*
|
2010-03-25 |
2019-03-21 |
Ucb Biopharma Sprl |
Disülfür stabilize edilmiş DVD-IG molekülleri.
|
|
AR080793A1
(es)
|
2010-03-26 |
2012-05-09 |
Roche Glycart Ag |
Anticuerpos biespecificos
|
|
US8557961B2
(en)
|
2010-04-02 |
2013-10-15 |
Amunix Operating Inc. |
Alpha 1-antitrypsin compositions and methods of making and using same
|
|
EP2552967A4
(en)
*
|
2010-04-02 |
2014-10-08 |
Amunix Operating Inc |
BINDING FUSION PROTEINS, BINDING FUSION PROTEIN MEDICINAL CONJUGATES, XTEN MEDICAMENT CONJUGATES, AND METHOD FOR THEIR PREPARATION AND USE
|
|
EP2556172A4
(en)
|
2010-04-06 |
2013-10-30 |
Caris Life Sciences Luxembourg Holdings |
CIRCULATING BIOMARKERS FOR DISEASES
|
|
WO2011127299A1
(en)
*
|
2010-04-09 |
2011-10-13 |
The General Hospital Corporation |
Methods for the treatment of autoimmune diseases
|
|
WO2012009544A2
(en)
*
|
2010-07-14 |
2012-01-19 |
Amgen Inc. |
Domain insertion immunoglobulin
|
|
WO2012009705A1
(en)
|
2010-07-15 |
2012-01-19 |
Zyngenia, Inc. |
Ang-2 binding complexes and uses thereof
|
|
JP6146913B2
(ja)
|
2010-08-02 |
2017-06-14 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． |
Ｖｌドメインを含む結合タンパク質を作製するマウス
|
|
TW201206473A
(en)
|
2010-08-03 |
2012-02-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
JP5758004B2
(ja)
*
|
2010-08-24 |
2015-08-05 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
ジスルフィドによって安定化されたＦｖ断片を含む二重特異性抗体
|
|
CN103068847B
(zh)
*
|
2010-08-24 |
2019-05-07 |
罗切格利卡特公司 |
可活化的双特异性抗体
|
|
CA2809433A1
(en)
|
2010-08-26 |
2012-03-01 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
US8993727B2
(en)
|
2010-09-22 |
2015-03-31 |
Amgen Inc. |
Carrier immunoglobulins and uses thereof
|
|
EP3604549A1
(en)
|
2010-11-08 |
2020-02-05 |
The Board of Trustees of the Leland Stanford Junior University |
Fusion proteins comprising an engineered knottin peptide and uses thereof
|
|
EP2643353A1
(en)
*
|
2010-11-24 |
2013-10-02 |
Novartis AG |
Multispecific molecules
|
|
UY33826A
(es)
*
|
2010-12-22 |
2012-07-31 |
Abbott Lab |
Proteínas de unión con dominios trivariables y sus usos
|
|
SG191153A1
(en)
|
2010-12-23 |
2013-07-31 |
Hoffmann La Roche |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
|
RU2013141078A
(ru)
|
2011-02-28 |
2015-04-10 |
Ф. Хоффманн-Ля Рош Аг |
Одновалентные антигенсвязывающие белки
|
|
BR112013019975A2
(pt)
|
2011-02-28 |
2017-08-01 |
Hoffmann La Roche |
proteínas de ligação de antígeno, composição farmacêutica, uso de uma proteína de ligação de antígeno, método para o tratamento de um paciente e método para a preparação de uma proteína de ligação de antígeno, ácido nucleico, vetor e célula hospedeira"
|
|
MX2013010011A
(es)
|
2011-03-01 |
2014-10-24 |
Amgen Inc |
Agentes de unión biespecífica.
|
|
US8846042B2
(en)
*
|
2011-05-16 |
2014-09-30 |
Fabion Pharmaceuticals, Inc. |
Multi-specific FAB fusion proteins and methods of use
|
|
CN103857699B
(zh)
|
2011-05-24 |
2016-08-31 |
泽恩格尼亚股份有限公司 |
多价和单价多特异性复合物及其用途
|
|
BR112013031762A2
(pt)
*
|
2011-06-16 |
2016-09-13 |
Novartis Ag |
proteínas solúveis para utilização como terapêuticos
|
|
EP2543680A1
(en)
|
2011-07-07 |
2013-01-09 |
Centre National de la Recherche Scientifique |
Multispecific mutated antibody Fab fragments
|
|
WO2013009843A1
(en)
*
|
2011-07-11 |
2013-01-17 |
Camas Incorporated |
Compositions against bacterial toxins
|
|
CN103906535B
(zh)
|
2011-08-15 |
2017-07-14 |
芝加哥大学 |
与葡萄球菌蛋白a的抗体相关的组合物和方法
|
|
KR101870555B1
(ko)
*
|
2011-08-23 |
2018-06-22 |
로슈 글리카트 아게 |
T 세포 활성화 항원 및 종양 항원에 대해 특이적인 이중특이적 항체 및 이의 사용 방법
|
|
WO2013026837A1
(en)
*
|
2011-08-23 |
2013-02-28 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
|
RS56879B1
(sr)
*
|
2011-08-23 |
2018-04-30 |
Roche Glycart Ag |
Bispecifične molekule koje vezuju antigen za aktiviranje t ćelija
|
|
RS57744B1
(sr)
*
|
2011-08-23 |
2018-12-31 |
Roche Glycart Ag |
Bispecifični antigen vezujući molekuli
|
|
US11098115B2
(en)
*
|
2011-09-29 |
2021-08-24 |
Apo-T B.V. |
Multi-specific binding molecules targeting aberrant cells
|
|
US9580509B2
(en)
*
|
2011-11-07 |
2017-02-28 |
Medimmune, Llc |
Multispecific and multivalent binding proteins and uses thereof
|
|
DK2794658T3
(en)
*
|
2011-12-19 |
2017-06-19 |
Synimmune Gmbh |
BISPECIFIC ANTIBODY MOLECULE
|
|
CA2861816C
(en)
*
|
2011-12-27 |
2022-11-08 |
Development Center For Biotechnology |
Light chain-bridged bispecific antibody
|
|
BR112014015851A2
(pt)
|
2011-12-30 |
2019-09-24 |
Abbvie Inc |
proteínas de ligação específicas duplas direcionadas contra il-13 e/ou il-17
|
|
US20130183307A1
(en)
|
2012-01-13 |
2013-07-18 |
Johan Renes |
Aberrant cell-restricted immunoglobulins provided with a toxic moiety
|
|
JP6486686B2
(ja)
*
|
2012-02-10 |
2019-03-20 |
ジェネンテック， インコーポレイテッド |
単鎖抗体及び他のヘテロ多量体
|
|
US9550830B2
(en)
|
2012-02-15 |
2017-01-24 |
Novo Nordisk A/S |
Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
|
|
RS57827B1
(sr)
|
2012-02-15 |
2018-12-31 |
Novo Nordisk As |
Antitela koja vezuju protein 1 prepoznavanja peptidoglikana
|
|
LT2814844T
(lt)
|
2012-02-15 |
2017-10-25 |
Novo Nordisk A/S |
Antikūnai, kurie jungiasi ir blokuoja ekspresuotą ant mieloidinių ląstelių inicijuojantį receptorių 1 (trem-1)
|
|
KR102283200B1
(ko)
|
2012-03-14 |
2021-07-29 |
리제너론 파마슈티칼스 인코포레이티드 |
다중특이성 항원-결합 분자 및 그것의 용도
|
|
US9593314B2
(en)
|
2012-03-16 |
2017-03-14 |
Covagen Ag |
Binding molecules with antitumoral activity
|
|
CA2871934C
(en)
*
|
2012-04-30 |
2023-06-13 |
Medimmune, Llc |
Molecules with reduced effector function and extended half-lives, compositions, and uses thereof
|
|
US9062120B2
(en)
|
2012-05-02 |
2015-06-23 |
Janssen Biotech, Inc. |
Binding proteins having tethered light chains
|
|
DK2847231T3
(da)
|
2012-05-10 |
2019-10-14 |
Bioatla Llc |
Multispecifikke monoklonale antistoffer
|
|
CN110256567B
(zh)
|
2012-06-27 |
2023-04-25 |
弗·哈夫曼-拉罗切有限公司 |
用于选择并产生含有至少两种不同结合实体的定制靶向实体的方法及其用途
|
|
JP6309002B2
(ja)
|
2012-06-27 |
2018-04-11 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
標的に特異的に結合する少なくとも１つの結合実体を含む抗体Ｆｃ領域結合体を作製するための方法およびその使用
|
|
SG11201503412RA
(en)
|
2012-11-01 |
2015-05-28 |
Abbvie Inc |
Anti-vegf/dll4 dual variable domain immunoglobulins and uses thereof
|
|
CN102973191A
(zh)
*
|
2012-11-29 |
2013-03-20 |
李安平 |
药物纸巾制造方法
|
|
CN103013370B
(zh)
*
|
2012-12-14 |
2014-12-10 |
京东方科技集团股份有限公司 |
一种各向异性导电胶膜及电子装置
|
|
WO2014100490A1
(en)
*
|
2012-12-19 |
2014-06-26 |
Adimab, Llc |
Multivalent antibody analogs, and methods of their preparation and use
|
|
GB201223276D0
(en)
|
2012-12-21 |
2013-02-06 |
Ucb Pharma Sa |
Antibodies and methods of producing same
|
|
ITTO20130012A1
(it)
*
|
2013-01-09 |
2014-07-10 |
Metheresis Translational Res S A |
Nuovi frammenti anticorpali, relative composizioni ed usi
|
|
US20140242077A1
(en)
*
|
2013-01-23 |
2014-08-28 |
Abbvie, Inc. |
Methods and compositions for modulating an immune response
|
|
CA2896370A1
(en)
*
|
2013-02-26 |
2014-09-04 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
|
EA201890895A1
(ru)
|
2013-03-15 |
2019-02-28 |
Зинджения, Инк. |
Мультивалентные и моновалентные мультиспецифические комплексы и их применение
|
|
US20140302037A1
(en)
*
|
2013-03-15 |
2014-10-09 |
Amgen Inc. |
BISPECIFIC-Fc MOLECULES
|
|
EP2970459A2
(en)
|
2013-03-15 |
2016-01-20 |
AbbVie Inc. |
Dual specific binding proteins directed against il-1beta and il-17
|
|
US20160009824A1
(en)
*
|
2013-03-15 |
2016-01-14 |
Merck Patent Gmbh |
Tetravalent bispecific antibodies
|
|
US10358494B2
(en)
|
2013-05-03 |
2019-07-23 |
Ohio State Innovation Foundation |
CS1-specific chimeric antigen receptor engineered immune effector cells
|
|
KR101722054B1
(ko)
*
|
2013-05-30 |
2017-03-31 |
최무현 |
반복사슬과 단량체의 복합체 간의 교차결속에 의해 형성된 초복합체 및 이의 용도
|
|
CA2918795A1
(en)
*
|
2013-07-25 |
2015-01-29 |
Cytomx Therapeutics, Inc. |
Multispecific antibodies, multispecific activatable antibodies and methods of using the same
|
|
WO2015048312A1
(en)
|
2013-09-26 |
2015-04-02 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
|
CA2922912A1
(en)
|
2013-10-11 |
2015-04-16 |
F. Hoffmann-La Roche Ag |
Multispecific domain exchanged common variable light chain antibodies
|
|
MX378238B
(es)
|
2013-10-14 |
2025-03-10 |
Janssen Biotech Inc |
Moléculas de unión con dominios de fibronectina de tipo iii modificadas con cisteína.
|
|
CA2934818C
(en)
*
|
2013-12-23 |
2022-05-17 |
John Babcook |
Antibodies comprising c-terminal light chain polypeptide extensions and conjugates and methods of use thereof
|
|
JP6706578B2
(ja)
|
2013-12-30 |
2020-06-10 |
エピムアブ バイオセラピューティクス インコーポレイテッド |
タンデム型Ｆａｂ免疫グロブリン及びその使用
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
EP3116909B1
(en)
|
2014-03-14 |
2019-11-13 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
|
CN106163547A
(zh)
|
2014-03-15 |
2016-11-23 |
诺华股份有限公司 |
使用嵌合抗原受体治疗癌症
|
|
SG10201808225TA
(en)
|
2014-03-21 |
2018-10-30 |
Regeneron Pharma |
Non-human animals that make single domain binding proteins
|
|
AU2015231025A1
(en)
|
2014-03-21 |
2016-09-15 |
Regeneron Pharmaceuticals, Inc. |
Vl antigen binding proteins exhibiting distinct binding characteristics
|
|
KR20160143808A
(ko)
*
|
2014-04-11 |
2016-12-14 |
메디뮨 엘엘씨 |
이중특이적 her2 항체
|
|
PE20170765A1
(es)
*
|
2014-05-29 |
2017-07-04 |
Macrogenics Inc |
Moleculas de union tri-especificas y metodos de uso de las mismas
|
|
CN104004092B
(zh)
*
|
2014-06-05 |
2015-07-29 |
深圳市第三人民医院 |
单基因编码的双或多价特异性抗hiv免疫粘附素
|
|
GB201411320D0
(en)
|
2014-06-25 |
2014-08-06 |
Ucb Biopharma Sprl |
Antibody construct
|
|
WO2015197598A2
(en)
*
|
2014-06-27 |
2015-12-30 |
Innate Pharma |
Multispecific antigen binding proteins
|
|
JP6822849B2
(ja)
|
2014-06-27 |
2021-01-27 |
イナート・ファルマ・ソシエテ・アノニムＩｎｎａｔｅ Ｐｈａｒｍａ Ｐｈａｒｍａ Ｓ．Ａ． |
多重特異的ＮＫｐ４６結合タンパク質
|
|
CN106661119A
(zh)
|
2014-07-01 |
2017-05-10 |
辉瑞公司 |
双特异性异二聚化双抗体及其用途
|
|
DK3172232T5
(en)
|
2014-07-17 |
2024-11-18 |
Novo Nordisk As |
Site directed mutagenesis of trem-1 antibodies for decreasing viscosity
|
|
BR112017001183A2
(pt)
|
2014-07-21 |
2017-11-28 |
Novartis Ag |
tratamento de câncer usando receptor de antígeno quimérico anti-bcma humanizado
|
|
CN107109419B
(zh)
|
2014-07-21 |
2020-12-22 |
诺华股份有限公司 |
使用cd33嵌合抗原受体治疗癌症
|
|
WO2016014530A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
WO2016014553A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
CN107108738A
(zh)
|
2014-07-25 |
2017-08-29 |
西托姆克斯治疗公司 |
抗cd3抗体、可活化抗cd3抗体、多特异性抗cd3抗体、多特异性可活化抗cd3抗体及其使用方法
|
|
EP4205749A1
(en)
|
2014-07-31 |
2023-07-05 |
Novartis AG |
Subset-optimized chimeric antigen receptor-containing cells
|
|
CA2958200A1
(en)
|
2014-08-14 |
2016-02-18 |
Novartis Ag |
Treatment of cancer using a gfr alpha-4 chimeric antigen receptor
|
|
ES2791248T3
(es)
|
2014-08-19 |
2020-11-03 |
Novartis Ag |
Receptor antigénico quimérico (CAR) anti-CD123 para su uso en el tratamiento del cáncer
|
|
AU2015314756A1
(en)
|
2014-09-13 |
2017-03-16 |
Novartis Ag |
Combination therapies of alk inhibitors
|
|
EA201790624A1
(ru)
|
2014-09-17 |
2017-08-31 |
Новартис Аг |
Нацеливание цитотоксических клеток с химерными рецепторами для адоптивной иммунотерапии
|
|
EP3201235A1
(en)
|
2014-10-01 |
2017-08-09 |
Medimmune Limited |
Antibodies to ticagrelor and methods of use
|
|
EP3200829B1
(en)
|
2014-10-01 |
2023-12-06 |
Medimmune, LLC |
Method of conjugating a polypeptide
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
CN114920840A
(zh)
|
2014-10-14 |
2022-08-19 |
诺华股份有限公司 |
针对pd-l1的抗体分子及其用途
|
|
WO2016090034A2
(en)
|
2014-12-03 |
2016-06-09 |
Novartis Ag |
Methods for b cell preconditioning in car therapy
|
|
CN107001482B
(zh)
|
2014-12-03 |
2021-06-15 |
豪夫迈·罗氏有限公司 |
多特异性抗体
|
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
|
US10172919B2
(en)
*
|
2014-12-29 |
2019-01-08 |
Academia Sinica |
Method for treating influenza A virus infection
|
|
JP2018503399A
(ja)
*
|
2015-01-14 |
2018-02-08 |
コンパス セラピューティクス リミテッド ライアビリティ カンパニー |
多特異性免疫調節抗原結合構築物
|
|
RU2017129236A
(ru)
|
2015-01-26 |
2019-03-07 |
Макродженикс, Инк. |
Мультивалентные молекулы, содержащие dr5-связывающие домены
|
|
JP2018510623A
(ja)
*
|
2015-02-20 |
2018-04-19 |
オハイオ・ステイト・イノベーション・ファウンデーション |
Ｎｋｇ２ｄ及び腫瘍関連抗原に対する二価抗体
|
|
EP3271403A1
(en)
|
2015-03-19 |
2018-01-24 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals that select for light chain variable regions that bind antigen
|
|
CN104804099B
(zh)
*
|
2015-04-01 |
2019-01-25 |
广州谱泰生物技术有限公司 |
一种重组h9n2亚型禽流感加强型多表位疫苗
|
|
WO2016164370A1
(en)
|
2015-04-06 |
2016-10-13 |
Ohio State Innovation Foundation |
Egfr-directed car therapy for glioblastoma
|
|
SG11201708191XA
(en)
|
2015-04-08 |
2017-11-29 |
Novartis Ag |
Cd20 therapies, cd22 therapies, and combination therapies with a cd19 chimeric antigen receptor (car) - expressing cell
|
|
US12128069B2
(en)
|
2015-04-23 |
2024-10-29 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
TWI773646B
(zh)
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗ｖｅｇｆ、ｐｄｇｆ及／或其受體之結合蛋白
|
|
JP6971153B2
(ja)
|
2015-06-23 |
2021-11-24 |
イナート・ファルマ・ソシエテ・アノニムInnate Pharma Pharma S.A. |
多重特異的ｎｋエンゲイジャータンパク質
|
|
EP3722318A1
(en)
|
2015-07-06 |
2020-10-14 |
Regeneron Pharmaceuticals, Inc. |
Multispecific antigen-binding molecules and uses thereof
|
|
WO2017011559A1
(en)
|
2015-07-14 |
2017-01-19 |
Medlmmune, Llc |
Compositions and methods for treating cancer
|
|
CN114272371A
(zh)
|
2015-07-29 |
2022-04-05 |
诺华股份有限公司 |
包含抗pd-1抗体分子的联合疗法
|
|
PT3317301T
(pt)
|
2015-07-29 |
2021-07-09 |
Novartis Ag |
Terapias de associação compreendendo moléculas de anticorpo contra lag-3
|
|
WO2017019897A1
(en)
|
2015-07-29 |
2017-02-02 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
|
WO2017019846A1
(en)
|
2015-07-30 |
2017-02-02 |
Macrogenics, Inc. |
Pd-1-binding molecules and methods use thereof
|
|
CA2985119C
(en)
|
2015-08-26 |
2021-01-26 |
Bison Therapeutics Inc. |
Multispecific antibody platform and related methods
|
|
CN105218679B
(zh)
*
|
2015-09-23 |
2018-01-12 |
天津市疾病预防控制中心 |
人偏肺病毒多表位抗原及其应用
|
|
KR20180053738A
(ko)
|
2015-09-30 |
2018-05-23 |
얀센 바이오테크 인코포레이티드 |
인간 cd40과 특이적으로 결합하는 길항적 항체 및 사용 방법
|
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
|
AU2016334041B2
(en)
|
2015-10-08 |
2023-02-09 |
Macrogenics, Inc. |
Combination therapy for the treatment of cancer
|
|
HUE057837T2
(hu)
|
2015-11-03 |
2022-06-28 |
Janssen Biotech Inc |
PD-1-et specifikusan kötõ ellenanyagok és alkalmazásaik
|
|
CR20180318A
(es)
|
2015-12-14 |
2018-09-19 |
Macrogenics Inc |
Moléculas biespecíficas que tienen inmunorreactividad con pd-1 y ctla-4, y métodos de uso de las mismas
|
|
EP4424322A3
(en)
|
2015-12-17 |
2025-04-16 |
Novartis AG |
Antibody molecules to pd-1 and uses thereof
|
|
AU2016369623A1
(en)
|
2015-12-17 |
2018-06-28 |
Novartis Ag |
Combination of c-Met inhibitor with antibody molecule to PD-1 and uses thereof
|
|
MA44140A
(fr)
|
2015-12-22 |
2021-05-19 |
Dana Farber Cancer Inst Inc |
Récepteur d'antigène chimérique (car) contre la mésothéline et anticorps contre l'inhibiteur de pd-l1 pour une utilisation combinée dans une thérapie anticancéreuse
|
|
CN109562162A
(zh)
*
|
2016-01-13 |
2019-04-02 |
指南针制药有限责任公司 |
多特异性免疫调节性抗原结合构建体
|
|
EP3851457A1
(en)
|
2016-01-21 |
2021-07-21 |
Novartis AG |
Multispecific molecules targeting cll-1
|
|
JP6991978B2
(ja)
|
2016-01-27 |
2022-02-03 |
メディミューン，エルエルシー |
定められるグリコシル化パターンを有する抗体を調製するための方法
|
|
KR102185867B1
(ko)
|
2016-02-06 |
2020-12-02 |
에피맙 바이오테라퓨틱스 인코포레이티드 |
Fabs-인-탠덤 면역글로불린 및 이의 용도
|
|
TW201730212A
(zh)
|
2016-02-17 |
2017-09-01 |
宏觀基因股份有限公司 |
Ｒｏｒ１－結合分子及其使用方法
|
|
EP3423482A1
(en)
|
2016-03-04 |
2019-01-09 |
Novartis AG |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
|
AU2017230091B2
(en)
|
2016-03-10 |
2022-04-07 |
Acceleron Pharma Inc. |
Activin type 2 receptor binding proteins and uses thereof
|
|
EP3430058A4
(en)
|
2016-03-15 |
2019-10-23 |
Generon (Shanghai) Corporation Ltd. |
MULTISPECIFIC FAB FUSION PROTEINS AND USES THEREOF
|
|
WO2017160879A1
(en)
*
|
2016-03-15 |
2017-09-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Knottin-drug conjugates and methods of using the same
|
|
EP3432924A1
(en)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
|
UA127341C2
(uk)
|
2016-04-15 |
2023-07-26 |
Мекроудженікс, Інк. |
Виділена b7-н3-зв'язувальна молекула
|
|
WO2017181119A2
(en)
|
2016-04-15 |
2017-10-19 |
Novartis Ag |
Compositions and methods for selective protein expression
|
|
US10501547B2
(en)
|
2016-04-22 |
2019-12-10 |
Acceleron Pharma Inc. |
ALK7 binding proteins and uses thereof
|
|
WO2017190079A1
(en)
|
2016-04-28 |
2017-11-02 |
Regeneron Pharmaceuticals, Inc. |
Methods of making multispecific antigen-binding molecules
|
|
AR108377A1
(es)
|
2016-05-06 |
2018-08-15 |
Medimmune Llc |
Proteínas de unión biespecíficas y sus usos
|
|
CN105907760A
(zh)
*
|
2016-05-31 |
2016-08-31 |
东北师范大学 |
靶向沉默TKS4的shRNA
|
|
US20210177896A1
(en)
|
2016-06-02 |
2021-06-17 |
Novartis Ag |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
|
CN109415435B
(zh)
*
|
2016-07-04 |
2024-01-16 |
豪夫迈·罗氏有限公司 |
新型抗体形式
|
|
JP7219376B2
(ja)
|
2016-07-15 |
2023-02-08 |
ノバルティス アーゲー |
キメラ抗原受容体をキナーゼ阻害薬と併用して使用したサイトカイン放出症候群の治療及び予防
|
|
AU2017302668B9
(en)
|
2016-07-28 |
2023-06-22 |
Novartis Ag |
Combination therapies of chimeric antigen receptors and PD-1 inhibitors
|
|
BR112019002035A2
(pt)
|
2016-08-01 |
2019-05-14 |
Novartis Ag |
tratamento de câncer usando um receptor de antígeno quimérico em combinação com um inibidor de uma molécula pró-macrófago m2
|
|
EP3497120A1
(en)
|
2016-08-12 |
2019-06-19 |
Janssen Biotech, Inc. |
Engineered antibodies and other fc-domain containing molecules with enhanced agonism and effector functions
|
|
CN109843916B
(zh)
|
2016-08-12 |
2023-10-31 |
詹森生物科技公司 |
具有增强的激动活性的Fc工程化抗TNFR超家族成员抗体及其使用方法
|
|
US20190225701A1
(en)
|
2016-09-26 |
2019-07-25 |
The Brigham And Women's Hospital, Inc. |
Regulators of b cell-mediated immunosuppression
|
|
SG10201913823VA
(en)
|
2016-10-07 |
2020-03-30 |
Novartis Ag |
Chimeric antigen receptors for the treatment of cancer
|
|
WO2018118780A1
(en)
*
|
2016-12-19 |
2018-06-28 |
Calico Biolabs, Inc. |
Monovalent and divalent binding proteins
|
|
EP3559034B1
(en)
|
2016-12-20 |
2020-12-02 |
H. Hoffnabb-La Roche Ag |
Combination therapy of anti-cd20/anti-cd3 bispecific antibodies and 4-1bb (cd137) agonists
|
|
CN110167591B
(zh)
|
2016-12-23 |
2023-09-26 |
宏观基因有限公司 |
Adam9结合分子及使用其的方法
|
|
WO2018140725A1
(en)
|
2017-01-26 |
2018-08-02 |
Novartis Ag |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
|
WO2018156740A1
(en)
|
2017-02-24 |
2018-08-30 |
Macrogenics, Inc. |
Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof
|
|
US20200048359A1
(en)
|
2017-02-28 |
2020-02-13 |
Novartis Ag |
Shp inhibitor compositions and uses for chimeric antigen receptor therapy
|
|
CN110582293B
(zh)
*
|
2017-03-31 |
2025-04-04 |
小利兰·斯坦福大学托管委员会 |
合成因子组合物及使用方法
|
|
CN110770255B
(zh)
*
|
2017-04-11 |
2025-07-01 |
因荷布瑞克斯生物科学公司 |
具有受限cd3结合的多特异性多肽构建体及其使用方法
|
|
US20200055948A1
(en)
|
2017-04-28 |
2020-02-20 |
Novartis Ag |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
US20200179511A1
(en)
|
2017-04-28 |
2020-06-11 |
Novartis Ag |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
AR111963A1
(es)
|
2017-05-26 |
2019-09-04 |
Univ California |
Método y moléculas
|
|
AU2018282094B2
(en)
|
2017-06-05 |
2024-06-27 |
Janssen Biotech, Inc. |
Antibodies that specifically bind PD-1 and methods of use
|
|
EP3635009A1
(en)
|
2017-06-07 |
2020-04-15 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for internalizing enzymes
|
|
WO2018237157A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
CD73 BINDING ANTIBODY MOLECULES AND USES THEREOF
|
|
JP2020525483A
(ja)
|
2017-06-27 |
2020-08-27 |
ノバルティス アーゲー |
抗ｔｉｍ−３抗体のための投与レジメンおよびその使用
|
|
CN111278858B
(zh)
|
2017-07-11 |
2024-07-23 |
指南针制药有限责任公司 |
结合人cd137的激动剂抗体及其用途
|
|
TW201918494A
(zh)
*
|
2017-07-19 |
2019-05-16 |
丹麥商諾佛 儂迪克股份有限公司 |
雙功能性化合物
|
|
IL319798A
(en)
|
2017-07-20 |
2025-05-01 |
Novartis Ag |
ANTI-LAG-3 Antibody Dosage Regimens and Their Uses
|
|
EP3625250B1
(en)
*
|
2017-07-21 |
2021-04-14 |
Trianni, Inc. |
Single chain vh and heavy chain antibodies
|
|
WO2019024979A1
(en)
*
|
2017-07-31 |
2019-02-07 |
Institute For Research In Biomedicine |
FUNCTIONAL DOMAIN ANTIBODIES IN THE ELBOW REGION
|
|
EP3666888A4
(en)
*
|
2017-08-10 |
2021-09-01 |
Good T Cells, Inc. |
T-CELL ACTIVATION METHOD FOR CANCER TREATMENT
|
|
AU2018347607B2
(en)
|
2017-10-14 |
2025-08-21 |
Cytomx Therapeutics, Inc. |
Antibodies, activatable antibodies, bispecific antibodies, and bispecific activatable antibodies and methods of use thereof
|
|
WO2019089753A2
(en)
|
2017-10-31 |
2019-05-09 |
Compass Therapeutics Llc |
Cd137 antibodies and pd-1 antagonists and uses thereof
|
|
US20210179709A1
(en)
|
2017-10-31 |
2021-06-17 |
Novartis Ag |
Anti-car compositions and methods
|
|
WO2019099838A1
(en)
|
2017-11-16 |
2019-05-23 |
Novartis Ag |
Combination therapies
|
|
EP3713961A2
(en)
|
2017-11-20 |
2020-09-30 |
Compass Therapeutics LLC |
Cd137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
|
BR112020011810A2
(pt)
|
2017-12-12 |
2020-11-17 |
Macrogenics, Inc. |
molécula de ligação cd16 x antígeno de doença, composição farmacêutica, uso da composição farmacêutica, e método para o tratamento de uma doença
|
|
US12247060B2
(en)
|
2018-01-09 |
2025-03-11 |
Marengo Therapeutics, Inc. |
Calreticulin binding constructs and engineered T cells for the treatment of diseases
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
US20210038659A1
(en)
|
2018-01-31 |
2021-02-11 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
WO2019160904A1
(en)
|
2018-02-15 |
2019-08-22 |
Macrogenics, Inc. |
Variant cd3-binding domains and their use in combination therapies for the treatment of disease
|
|
WO2019178362A1
(en)
|
2018-03-14 |
2019-09-19 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
KR102900511B1
(ko)
|
2018-04-02 |
2025-12-17 |
브리스톨-마이어스 스큅 컴퍼니 |
항-trem-1 항체 및 이의 용도
|
|
MX2020010638A
(es)
|
2018-04-11 |
2021-01-08 |
Inhibrx Inc |
Constructos de polipeptidos multiespecificos que tienen union a cd3 restringida y metodos y usos relacionados.
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
EP3784351A1
(en)
|
2018-04-27 |
2021-03-03 |
Novartis AG |
Car t cell therapies with enhanced efficacy
|
|
MX2020011487A
(es)
|
2018-04-30 |
2020-12-07 |
Regeneron Pharma |
Anticuerpos y moleculas biespecificas de union al antigeno que se unen a her2 y/o aplp2, conjugados y usos de estos.
|
|
WO2019210848A1
(en)
|
2018-05-03 |
2019-11-07 |
Shanghai Epimab Biotherapeutics Co., Ltd. |
High affinity antibodies to pd-1 and lag-3 and bispecific binding proteins made therefrom
|
|
CA3100021A1
(en)
|
2018-05-17 |
2019-11-21 |
Regeneron Pharmaceuticals, Inc. |
Anti-cd63 antibodies, conjugates, and uses thereof
|
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
|
JP2021525243A
(ja)
|
2018-05-21 |
2021-09-24 |
コンパス セラピューティクス リミテッド ライアビリティ カンパニー |
Ｎｋ細胞による標的細胞の殺傷を増進するための組成物および方法
|
|
KR20210011999A
(ko)
|
2018-05-24 |
2021-02-02 |
얀센 바이오테크 인코포레이티드 |
단일특이성 및 다중특이성 항-tmeff2 항체 및 이의 용도
|
|
US11746157B2
(en)
|
2018-05-24 |
2023-09-05 |
Janssen Biotech, Inc. |
PSMA binding agents and uses thereof
|
|
HRP20250621T1
(hr)
|
2018-05-24 |
2025-07-18 |
Janssen Biotech, Inc. |
Protutijela usmjerena na cd3 i njihove primjene
|
|
WO2019227003A1
(en)
|
2018-05-25 |
2019-11-28 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
JP7438988B2
(ja)
|
2018-06-13 |
2024-02-27 |
ノバルティス アーゲー |
Ｂｃｍａキメラ抗原受容体及びその使用
|
|
AU2019286396A1
(en)
|
2018-06-14 |
2020-12-17 |
Bioatla, Inc. |
Multi-specific antibody constructs
|
|
KR20210035173A
(ko)
|
2018-06-19 |
2021-03-31 |
아타르가, 엘엘씨 |
보체 성분 5에 대한 항체분자 및 이의 용도
|
|
CA3105448A1
(en)
|
2018-07-03 |
2020-01-09 |
Elstar Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
JP7651450B2
(ja)
*
|
2018-07-24 |
2025-03-26 |
インヒブルクス バイオサイエンシズ インコーポレイテッド |
制約されたｃｄ３結合ドメインおよび受容体結合領域を含有する多重特異性ポリペプチド構築物ならびにそれを使用する方法
|
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
|
EP3847196A4
(en)
|
2018-09-07 |
2023-01-04 |
ITabMed (HK) Limited |
BISPECIFIC ANTIGEN BINDING PROTEINS AND USES THEREOF
|
|
CA3115089A1
(en)
|
2018-10-11 |
2020-04-16 |
Inhibrx, Inc. |
Dll3 single domain antibodies and therapeutic compositions thereof
|
|
EP4578507A3
(en)
|
2018-11-01 |
2025-11-12 |
Gracell Biotechnologies (Shanghai) Co., Ltd. |
Compositions and methods for t cell engineering
|
|
US12466892B2
(en)
|
2018-11-08 |
2025-11-11 |
The Regents Of The University Of California |
Systems and methods for targeting cancer cells
|
|
CA3119161A1
(en)
|
2018-11-13 |
2020-05-22 |
Compass Therapeutics Llc |
Multispecific binding constructs against checkpoint molecules and uses thereof
|
|
CA3122727A1
(en)
|
2018-12-20 |
2020-06-25 |
Novartis Ag |
Pharmaceutical combinations
|
|
WO2020128972A1
(en)
|
2018-12-20 |
2020-06-25 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
MX2021009763A
(es)
|
2019-02-15 |
2021-09-08 |
Novartis Ag |
Derivados de 3-(1-oxo-5-(piperidin-4-il)isoindolin-2-il)piperidina -2,6-diona y usos de los mismos.
|
|
US10871640B2
(en)
|
2019-02-15 |
2020-12-22 |
Perkinelmer Cellular Technologies Germany Gmbh |
Methods and systems for automated imaging of three-dimensional objects
|
|
AU2020222346B2
(en)
|
2019-02-15 |
2021-12-09 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
CN119039441A
(zh)
|
2019-02-21 |
2024-11-29 |
马伦戈治疗公司 |
与nkp30结合的抗体分子及其用途
|
|
WO2020172571A1
(en)
|
2019-02-21 |
2020-08-27 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to t cell related cancer cells and uses thereof
|
|
WO2020172553A1
(en)
|
2019-02-22 |
2020-08-27 |
Novartis Ag |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
|
EP3931224A4
(en)
|
2019-02-26 |
2023-03-01 |
Janssen Biotech, Inc. |
COMBINATION TREATMENTS AND PATIENT STRATIFICATION WITH ANTI-EGFR/C-MET BISPECIFIC ANTIBODIES
|
|
CA3135430A1
(en)
|
2019-03-29 |
2020-10-08 |
Atarga, Llc |
Anti fgf23 antibody
|
|
US20200319174A1
(en)
*
|
2019-04-17 |
2020-10-08 |
Jiangnan University |
Method for Detecting Human Soluble Asialoglycoprotein Receptor
|
|
WO2020212947A1
(en)
|
2019-04-19 |
2020-10-22 |
Janssen Biotech, Inc. |
Methods of treating prostate cancer with an anti- psma/cd3 antibody
|
|
JP7741732B2
(ja)
|
2019-05-07 |
2025-09-18 |
グレイセル・バイオテクノロジーズ（シャンハイ）カンパニー・リミテッド |
Ｂｃｍａを標的とする操作された免疫細胞及びその使用
|
|
JP7686571B2
(ja)
|
2019-05-08 |
2025-06-02 |
ヤンセン バイオテツク，インコーポレーテツド |
Ｔ細胞媒介性免疫を調節するための材料及び方法
|
|
MY208668A
(en)
|
2019-05-14 |
2025-05-23 |
Janssen Biotech Inc |
Combination therapies with bispecific anti-egfr/c-met antibodies and 3rd generation egfr tyrosine kinase inhibitors
|
|
UY38701A
(es)
|
2019-05-21 |
2020-12-31 |
Novartis Ag |
Moléculas de unión a cd19, conjugados, composiciones que las comprenden y usos de las mismas
|
|
CA3146341A1
(en)
|
2019-07-30 |
2021-02-04 |
Aaron L. Kurtzman |
Bispecific anti lrrc15 and cd3epsilun antibudies
|
|
KR20220087498A
(ko)
|
2019-10-21 |
2022-06-24 |
노파르티스 아게 |
Tim-3 억제제 및 그의 용도
|
|
MX2022004766A
(es)
|
2019-10-21 |
2022-05-16 |
Novartis Ag |
Terapias combinadas con venetoclax e inhibidores de tim-3.
|
|
CN118580365A
(zh)
*
|
2019-11-06 |
2024-09-03 |
西雅图免疫公司 |
制导和导航控制蛋白及其制备和使用方法
|
|
JP7714545B2
(ja)
|
2019-11-26 |
2025-07-29 |
ノバルティス アーゲー |
キメラ抗原受容体及びその使用
|
|
CN120943966A
(zh)
*
|
2019-12-05 |
2025-11-14 |
艾贝乐医药科技有限公司 |
TriAx抗体的组合物及其制备和使用方法
|
|
IL293834A
(en)
|
2019-12-20 |
2022-08-01 |
Novartis Ag |
Combination of anti tim-3 antibody mbg453 and anti tgf-beta antibody nis793, with or without decitabine or the anti pd-1 antibody spartalizumab, for treating myelofibrosis and myelodysplastic syndrome
|
|
JP2023509708A
(ja)
|
2020-01-03 |
2023-03-09 |
マレンゴ・セラピューティクス，インコーポレーテッド |
抗ｔｃｒ抗体分子およびその使用
|
|
KR20220128389A
(ko)
|
2020-01-17 |
2022-09-20 |
노파르티스 아게 |
골수이형성 증후군 또는 만성 골수단핵구성 백혈병을 치료하는데 사용하기 위한 tim-3 억제제 및 저메틸화제를 포함하는 조합물
|
|
WO2021146636A1
(en)
|
2020-01-17 |
2021-07-22 |
Becton, Dickinson And Company |
Methods and compositions for single cell secretomics
|
|
JOP20220184A1
(ar)
|
2020-02-12 |
2023-01-30 |
Janssen Biotech Inc |
علاج مصابي السرطان ممن لديهم طفرات تخطي c-Met إكسون14
|
|
KR20220147109A
(ko)
|
2020-02-27 |
2022-11-02 |
노파르티스 아게 |
키메라 항원 수용체 발현 세포의 제조 방법
|
|
US20230086069A1
(en)
*
|
2020-03-03 |
2023-03-23 |
Systimmune, Inc. |
Anti-cd19 antibodies and methods of using and making thereof
|
|
TWI874613B
(zh)
*
|
2020-03-17 |
2025-03-01 |
美商西雅圖免疫公司 |
微型導引和導航控制(miniGNC)類抗體蛋白及其製造和使用方法
|
|
CR20220594A
(es)
|
2020-05-27 |
2023-01-17 |
Janssen Biotech Inc |
Proteins comprising cd3 antigen binding domains and uses thereof
|
|
KR20230027056A
(ko)
|
2020-06-23 |
2023-02-27 |
노파르티스 아게 |
3-(1-옥소이소인돌린-2-일)피페리딘-2,6-디온 유도체를 포함하는 투약 요법
|
|
US20240279353A1
(en)
|
2020-07-06 |
2024-08-22 |
Kiromic BioPharma, Inc. |
Mesothelin isoform binding molecules and chimeric pd1 receptor molecules, cells containing the same and uses thereof
|
|
CA3176556A1
(en)
|
2020-07-16 |
2022-01-20 |
Novartis Ag |
Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules
|
|
WO2022026592A2
(en)
|
2020-07-28 |
2022-02-03 |
Celltas Bio, Inc. |
Antibody molecules to coronavirus and uses thereof
|
|
US20230271940A1
(en)
|
2020-08-03 |
2023-08-31 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
WO2022043558A1
(en)
|
2020-08-31 |
2022-03-03 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
EP4204021A1
(en)
|
2020-08-31 |
2023-07-05 |
Advanced Accelerator Applications International S.A. |
Method of treating psma-expressing cancers
|
|
CN113416249B
(zh)
*
|
2020-10-21 |
2023-04-07 |
北京智仁美博生物科技有限公司 |
针对破伤风毒素的组合物
|
|
TW202233674A
(zh)
|
2020-10-28 |
2022-09-01 |
美商健生生物科技公司 |
用於調節δγ鏈介導之免疫的組成物及方法
|
|
EP4240765A2
(en)
|
2020-11-06 |
2023-09-13 |
Novartis AG |
Antibody fc variants
|
|
AU2021377176A1
(en)
*
|
2020-11-11 |
2023-06-22 |
Hq Han |
Bifunctional antagonists of activin/tgf-beta and rankl and uses thereof
|
|
IL302700A
(en)
|
2020-11-13 |
2023-07-01 |
Novartis Ag |
Combination therapies with chimeric antigen receptor (car)-expressing cells
|
|
WO2022108627A1
(en)
|
2020-11-18 |
2022-05-27 |
Kiromic Biopharma, Inc.Kiromic Biopharma, Inc. |
Gamma-delta t cell manufacturing processes and chimeric pd1 receptor molecules
|
|
JP2024504758A
(ja)
|
2021-01-28 |
2024-02-01 |
ヤンセン バイオテツク，インコーポレーテツド |
Ｐｓｍａ結合タンパク質及びその使用
|
|
EP4284510A1
(en)
|
2021-01-29 |
2023-12-06 |
Novartis AG |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
|
WO2022171736A1
(en)
|
2021-02-10 |
2022-08-18 |
Limagrain Europe |
Multiplex targeted recombinations for trait introgression applications
|
|
EP4304644A1
(en)
|
2021-03-09 |
2024-01-17 |
Janssen Biotech, Inc. |
Treatment of cancers lacking egfr-activating mutations
|
|
JP2024514072A
(ja)
*
|
2021-03-31 |
2024-03-28 |
ハングズホウ エクセジェネシス バイオ エルティーディー． |
Ｖｅｇｆ及びアンジオポエチンを標的とする融合分子及びその使用
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
TW202309094A
(zh)
|
2021-05-18 |
2023-03-01 |
美商健生生物科技公司 |
用於識別癌症患者以進行組合治療之方法
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
WO2023044483A2
(en)
|
2021-09-20 |
2023-03-23 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
CA3176410A1
(en)
*
|
2021-09-24 |
2023-03-24 |
Kashiv Biosciences, Llc |
An improved process for preparation of stable protein solution
|
|
US20250034559A1
(en)
|
2021-11-17 |
2025-01-30 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
US20230183360A1
(en)
|
2021-12-09 |
2023-06-15 |
Janssen Biotech, Inc. |
Use of Amivantamab to Treat Colorectal Cancer
|
|
TW202342057A
(zh)
|
2022-02-07 |
2023-11-01 |
美商健生生物科技公司 |
用於減少用ｅｇｆｒ／ｍｅｔ雙特異性抗體治療之患者的輸注相關反應之方法
|
|
JP2025505650A
(ja)
|
2022-02-07 |
2025-02-28 |
ビステラ， インコーポレイテッド |
抗イディオタイプ抗体分子及びその使用
|
|
JP2025510232A
(ja)
|
2022-03-29 |
2025-04-14 |
エヌジーエム バイオファーマシューティカルス，インコーポレーテッド |
Ｉｌｔ３及びｃｄ３結合剤及びその使用方法
|
|
US20250295809A1
(en)
|
2022-05-13 |
2025-09-25 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
US20240317866A1
(en)
|
2022-06-30 |
2024-09-26 |
Janssen Biotech, Inc. |
Use of Anti-EGFR/Anti-Met Antibody to Treat Gastric or Esophageal Cancer
|
|
TW202435912A
(zh)
|
2022-08-03 |
2024-09-16 |
美商航海家醫療公司 |
用於穿過血腦屏障之組合物及方法
|
|
WO2024089551A1
(en)
|
2022-10-25 |
2024-05-02 |
Janssen Biotech, Inc. |
Msln and cd3 binding agents and methods of use thereof
|
|
AU2023383923A1
(en)
|
2022-11-24 |
2025-07-10 |
Beone Medicines I Gmbh |
Anti-cea antibody drug conjugates and methods of use
|
|
IL322127A
(en)
|
2023-01-19 |
2025-09-01 |
Beone Medicines I Gmbh |
Anti-cmet antibodies and methods of use
|
|
WO2024168061A2
(en)
|
2023-02-07 |
2024-08-15 |
Ayan Therapeutics Inc. |
Antibody molecules binding to sars-cov-2
|
|
EP4676975A1
(en)
|
2023-03-03 |
2026-01-14 |
Beone Medicines I GmbH |
Muc1 and cd16a antibodies and methods of use
|
|
WO2024183637A1
(en)
|
2023-03-03 |
2024-09-12 |
Beigene Switzerland Gmbh |
Muc1 antibodies and methods of use
|
|
TW202436344A
(zh)
|
2023-03-03 |
2024-09-16 |
瑞士商百濟神州瑞士有限責任公司 |
Ｃｄ１６ａ抗體及使用方法
|
|
WO2024184810A1
(en)
|
2023-03-06 |
2024-09-12 |
Beigene Switzerland Gmbh |
Anti-cldn6 and anti-cd3 multispecific antibodies and methods of use
|
|
TW202436354A
(zh)
|
2023-03-06 |
2024-09-16 |
瑞士商百濟神州瑞士有限責任公司 |
抗cldn6抗體以及其使用方法
|
|
TW202436345A
(zh)
|
2023-03-06 |
2024-09-16 |
瑞士商百濟神州瑞士有限責任公司 |
抗ｃｄ３多特異性抗體及使用方法
|
|
AU2024236678A1
(en)
|
2023-03-13 |
2025-10-30 |
Janssen Biotech, Inc. |
Combination therapies with bi-specific anti-egfr/c-met antibodies and anti-pd-1 antibodies
|
|
CA3228195A1
(en)
|
2023-05-23 |
2025-06-30 |
Janssen Biotech, Inc. |
Methods for treatment of non-small cell lung cancer (nsclc)
|
|
UY40783A
(es)
|
2023-06-12 |
2024-12-31 |
Amgen Inc |
Proteínas de unión a agonistas del receptor beta de linfotoxina
|
|
WO2025032508A1
(en)
|
2023-08-07 |
2025-02-13 |
Janssen Biotech, Inc. |
Enpp3 and cd3 binding agents and methods of use thereof
|
|
US20250136688A1
(en)
|
2023-08-07 |
2025-05-01 |
Janssen Biotech, Inc. |
Stabilized cd3 antigen binding agents and methods of use thereof
|
|
WO2025052273A1
(en)
|
2023-09-05 |
2025-03-13 |
Janssen Biotech, Inc. |
Methods of treating non-small cell lung cancer
|
|
WO2025079020A1
(en)
|
2023-10-12 |
2025-04-17 |
Janssen Biotech, Inc. |
First line treatment in egfr exon 20 insertion-mutated advanced non-small cell lung cancer
|
|
WO2025122634A1
(en)
|
2023-12-05 |
2025-06-12 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
WO2025126102A1
(en)
|
2023-12-12 |
2025-06-19 |
Janssen Biotech, Inc. |
Enpp3 × cd3 bispecific antibodies and use thereof
|
|
WO2025153988A1
(en)
|
2024-01-16 |
2025-07-24 |
Janssen Biotech, Inc. |
Use of amivantamab to treat colorectal cancer
|
|
WO2025158277A1
(en)
|
2024-01-22 |
2025-07-31 |
Janssen Biotech, Inc. |
Use of amivantamab to treat head and neck cancer
|
|
WO2025191459A1
(en)
|
2024-03-11 |
2025-09-18 |
Janssen Biotech, Inc. |
Use of bispecific anti-egfr/c-met antibodies to treat solid tumors
|
