|
AU775373B2
(en)
|
1999-10-01 |
2004-07-29 |
Immunogen, Inc. |
Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
|
|
US7097840B2
(en)
|
2000-03-16 |
2006-08-29 |
Genentech, Inc. |
Methods of treatment using anti-ErbB antibody-maytansinoid conjugates
|
|
US6333410B1
(en)
|
2000-08-18 |
2001-12-25 |
Immunogen, Inc. |
Process for the preparation and purification of thiol-containing maytansinoids
|
|
AR030612A1
(es)
*
|
2000-09-12 |
2003-08-27 |
Smithkline Beecham Corp |
Procedimiento e intermedios
|
|
US20020156274A1
(en)
*
|
2001-03-16 |
2002-10-24 |
Terfloth Gerald J. |
Process for preparing maytansinol
|
|
US20090123470A1
(en)
*
|
2001-03-26 |
2009-05-14 |
The Macfarlane Burnet Istitute For Medical Research And Public Health Ltd. |
Antibodies Against Cancer
|
|
AUPR395801A0
(en)
*
|
2001-03-26 |
2001-04-26 |
Austin Research Institute, The |
Antibodies against cancer
|
|
US7582299B2
(en)
*
|
2001-04-26 |
2009-09-01 |
Biogen Idec Ma Inc. |
Cripto-specific antibodies
|
|
PT1390389E
(pt)
*
|
2001-04-26 |
2009-04-03 |
Biogen Idec Inc |
Anticorpos que bloqueiam o cripto e as utilizações dos mesmos
|
|
US20100056762A1
(en)
|
2001-05-11 |
2010-03-04 |
Old Lloyd J |
Specific binding proteins and uses thereof
|
|
EP1392359B2
(en)
|
2001-05-11 |
2013-03-13 |
Ludwig Institute for Cancer Research Ltd. |
Specific binding proteins and uses thereof
|
|
US6441163B1
(en)
*
|
2001-05-31 |
2002-08-27 |
Immunogen, Inc. |
Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents
|
|
EP2277542B1
(en)
|
2001-06-01 |
2014-04-16 |
Cornell Research Foundation Inc. |
Modified antibodies to prostrate-specific membrane antigen and uses thereof
|
|
US20050053611A1
(en)
*
|
2001-06-08 |
2005-03-10 |
Xiaoke Hao |
Pharmaceutical kit comprising anti-human seminal plasma protein single chain antibody/human carboxypeptidase fusion protein and prodrug
|
|
US20090297531A1
(en)
*
|
2001-06-20 |
2009-12-03 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US7803915B2
(en)
*
|
2001-06-20 |
2010-09-28 |
Genentech, Inc. |
Antibody compositions for the diagnosis and treatment of tumor
|
|
CA2633171C
(en)
*
|
2001-06-20 |
2012-11-20 |
Genentech, Inc. |
Antibodies against tumor-associated antigenic target (tat) polypeptides
|
|
DE10215336A1
(de)
*
|
2002-03-28 |
2003-10-23 |
Schering Ag |
N-Methyl-Homocysteine und ihre Verwendung sowie Verfahren zu ihrer Herstellung
|
|
AU2003228998A1
(en)
*
|
2002-05-13 |
2003-12-02 |
Smithkline Beecham Corporation |
Process for preparing maytansinol
|
|
US7767803B2
(en)
|
2002-06-18 |
2010-08-03 |
Archemix Corp. |
Stabilized aptamers to PSMA and their use as prostate cancer therapeutics
|
|
JP2005533794A
(ja)
*
|
2002-06-18 |
2005-11-10 |
アーケミックス コーポレイション |
アプタマー−毒素分子およびこれを使用する方法
|
|
US20040249130A1
(en)
*
|
2002-06-18 |
2004-12-09 |
Martin Stanton |
Aptamer-toxin molecules and methods for using same
|
|
CA2491017A1
(en)
*
|
2002-07-03 |
2004-01-15 |
Immunogen, Inc. |
Antibodies to non-shed muc1 and muc16, and uses thereof
|
|
US8853376B2
(en)
|
2002-11-21 |
2014-10-07 |
Archemix Llc |
Stabilized aptamers to platelet derived growth factor and their use as oncology therapeutics
|
|
US7432088B2
(en)
|
2003-05-08 |
2008-10-07 |
Immunogen Inc. |
Methods for the production of ansamitocins
|
|
US8088387B2
(en)
*
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
KR101424624B1
(ko)
*
|
2003-05-14 |
2014-07-31 |
이뮤노젠 아이엔씨 |
약물 콘쥬게이트 조성물
|
|
PL3524611T3
(pl)
|
2003-05-20 |
2021-06-14 |
Immunogen, Inc. |
Udoskonalone czynniki cytotoksyczne zawierające nowe maitansynoidy
|
|
US7276497B2
(en)
*
|
2003-05-20 |
2007-10-02 |
Immunogen Inc. |
Cytotoxic agents comprising new maytansinoids
|
|
CA2530605A1
(en)
*
|
2003-06-27 |
2005-05-26 |
Diadexus, Inc. |
Pro104 antibody compositions and methods of use
|
|
US7834155B2
(en)
*
|
2003-07-21 |
2010-11-16 |
Immunogen Inc. |
CA6 antigen-specific cytotoxic conjugate and methods of using the same
|
|
EA014640B1
(ru)
*
|
2003-07-21 |
2010-12-30 |
Иммьюноджен, Инк. |
Антитело или его эпитоп-связывающий фрагмент, которые связываются с гликотопом са6, и способы их применения
|
|
EP1656359B1
(en)
*
|
2003-08-14 |
2012-11-28 |
Merck Sharp & Dohme Corp. |
Macrocyclic beta-secretase inhibitors for the treatment of alzheimer's disease
|
|
US6890962B1
(en)
*
|
2003-11-25 |
2005-05-10 |
Chevron U.S.A. Inc. |
Gas-to-liquid CO2 reduction by use of H2 as a fuel
|
|
KR20120064120A
(ko)
|
2004-06-01 |
2012-06-18 |
제넨테크, 인크. |
항체 약물 접합체 및 방법
|
|
US7541330B2
(en)
*
|
2004-06-15 |
2009-06-02 |
Kosan Biosciences Incorporated |
Conjugates with reduced adverse systemic effects
|
|
CA2486285C
(en)
*
|
2004-08-30 |
2017-03-07 |
Viktor S. Goldmakher |
Immunoconjugates targeting syndecan-1 expressing cells and use thereof
|
|
JP2008520670A
(ja)
*
|
2004-11-17 |
2008-06-19 |
メルク エンド カムパニー インコーポレーテッド |
アルツハイマー病の治療のための大環状第三アミンβ−セクレターゼ阻害剤
|
|
AU2005309708A1
(en)
*
|
2004-11-23 |
2006-06-01 |
Merck & Co., Inc. |
Macrocyclic aminopyridyl beta-secretase inhibitors for the treatment of Alzheimer's disease
|
|
ES2408704T3
(es)
|
2005-01-05 |
2013-06-21 |
Biogen Idec Ma Inc. |
Moléculas de unión a Cripto
|
|
US7301019B2
(en)
*
|
2005-01-21 |
2007-11-27 |
Immunogen, Inc. |
Method for the preparation of maytansinoid esters
|
|
CA2597407C
(en)
*
|
2005-02-11 |
2013-09-10 |
Immunogen, Inc. |
Process for preparing stable drug conjugates
|
|
WO2006096754A2
(en)
*
|
2005-03-07 |
2006-09-14 |
Archemix Corp. |
Stabilized aptamers to psma and their use as prostate cancer therapeutics
|
|
EP3058955B1
(en)
|
2005-03-24 |
2019-05-29 |
Millennium Pharmaceuticals, Inc. |
Antibodies that bind ov064 and methods of use therefor
|
|
WO2007019232A2
(en)
*
|
2005-08-03 |
2007-02-15 |
Immunogen, Inc. |
Immunoconjugate formulations
|
|
WO2007021674A2
(en)
*
|
2005-08-09 |
2007-02-22 |
Millennium Pharmaceuticals, Inc. |
Method of acylating maytansinol with chiral amino acids
|
|
EP3539572A1
(en)
|
2005-08-24 |
2019-09-18 |
ImmunoGen, Inc. |
Process for preparing maytansinoid antibody conjugates
|
|
WO2007056550A2
(en)
*
|
2005-11-08 |
2007-05-18 |
Immunogen, Inc. |
Processes for preparation of maytansinol
|
|
EP1806365A1
(en)
|
2006-01-05 |
2007-07-11 |
Boehringer Ingelheim International GmbH |
Antibody molecules specific for fibroblast activation protein and immunoconjugates containing them
|
|
ES2673822T3
(es)
|
2006-07-18 |
2018-06-25 |
Sanofi |
Anticuerpo antagonista contra EphA2 para el tratamiento de cáncer
|
|
EP1914242A1
(en)
*
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
|
CA2670471A1
(en)
|
2006-11-22 |
2008-06-05 |
Adnexus, A Bristol-Myers Squibb R&D Company (A Delaware Corporation) |
Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including igf-ir
|
|
US9090693B2
(en)
|
2007-01-25 |
2015-07-28 |
Dana-Farber Cancer Institute |
Use of anti-EGFR antibodies in treatment of EGFR mutant mediated disease
|
|
US20100144599A1
(en)
|
2007-02-02 |
2010-06-10 |
Bristol-Myers Squibb Company |
Vegf pathway blockade
|
|
ES2542152T3
(es)
|
2007-03-15 |
2015-07-31 |
Ludwig Institute For Cancer Research Ltd. |
Método de tratamiento que emplea anticuerpos de EGFR e inhibidores de Src y formulaciones relacionadas
|
|
BRPI0809435A2
(pt)
|
2007-03-27 |
2014-09-09 |
Sea Lane Biotechnologies, Llc |
Constructos e bibliotecas que compreendem sequências de cadeia leve substituida de anticorpos
|
|
US20090011060A1
(en)
*
|
2007-07-06 |
2009-01-08 |
Peter Koepke |
Campsiandra angustifolia extract and methods of extracting and using such extract
|
|
US20090017140A1
(en)
*
|
2007-07-09 |
2009-01-15 |
Peter Koepke |
Maytenus abenfolia extract and methods of extracting and using such extract
|
|
NZ583318A
(en)
|
2007-07-16 |
2012-07-27 |
Genentech Inc |
Humanized anti-cd79b antibodies and immunoconjugates and methods of use
|
|
DK2474557T3
(da)
|
2007-07-16 |
2014-11-10 |
Genentech Inc |
Anti-CD79b-antistoffer og immunkonjugater og fremgangsmåder til anvendelse
|
|
US20090035395A1
(en)
*
|
2007-08-01 |
2009-02-05 |
Peter Koepke |
Spondias mombin l. extract and methods of extracting and using such extract
|
|
CN108424454B
(zh)
|
2007-08-14 |
2022-05-31 |
路德维格癌症研究所有限公司 |
靶向egf受体的单克隆抗体175及其衍生物和用途
|
|
CN111909273B
(zh)
*
|
2007-08-29 |
2024-03-26 |
塞诺菲-安万特股份有限公司 |
人源化的抗-cxcr5抗体、其衍生物及它们的应用
|
|
US7879369B2
(en)
*
|
2007-09-18 |
2011-02-01 |
Selvamedica, Llc |
Combretum laurifolium Mart. extract and methods of extracting and using such extract
|
|
EP2050764A1
(en)
|
2007-10-15 |
2009-04-22 |
sanofi-aventis |
Novel polyvalent bispecific antibody format and uses thereof
|
|
EP2240516B1
(en)
*
|
2007-12-26 |
2015-07-08 |
Biotest AG |
Methods and agents for improving targeting of cd138 expressing tumor cells
|
|
CA2710453C
(en)
|
2007-12-26 |
2019-07-02 |
Biotest Ag |
Agents targeting cd138 and uses thereof
|
|
ES2526433T3
(es)
*
|
2007-12-26 |
2015-01-12 |
Biotest Ag |
Inmunoconjugados dirigidos a CD138 y usos de los mismos
|
|
JP2011507933A
(ja)
*
|
2007-12-26 |
2011-03-10 |
バイオテスト・アクチエンゲゼルシヤフト |
免疫複合体の細胞傷害性副作用の低減及び有効性の改善方法
|
|
SG187517A1
(en)
|
2008-01-31 |
2013-02-28 |
Genentech Inc |
Anti-cd79b antibodies and immunoconjugates and methods of use
|
|
NZ602675A
(en)
|
2008-03-18 |
2014-03-28 |
Genentech Inc |
Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use
|
|
KR20200058590A
(ko)
|
2008-04-30 |
2020-05-27 |
이뮤노젠 아이엔씨 |
가교제 및 그 용도
|
|
PE20091931A1
(es)
|
2008-05-22 |
2009-12-31 |
Bristol Myers Squibb Co |
Proteinas de dominio de armazon basadas en fibronectina multivalentes
|
|
JP5611210B2
(ja)
|
2008-09-07 |
2014-10-22 |
グリコネックス インコーポレイテッド |
抗拡張ｉ型スフィンゴ糖脂質抗体、その誘導体および使用
|
|
WO2010120561A1
(en)
|
2009-04-01 |
2010-10-21 |
Genentech, Inc. |
Anti-fcrh5 antibodies and immunoconjugates and methods of use
|
|
US8481694B2
(en)
|
2009-04-29 |
2013-07-09 |
Bio-Rad Laboratories, Inc. |
Purification of immunoconjugates
|
|
AR076284A1
(es)
|
2009-04-29 |
2011-06-01 |
Bayer Schering Pharma Ag |
Inmunoconjugados de antimesotelina y usos de los mismos
|
|
EP2998405B1
(en)
|
2009-05-13 |
2019-12-11 |
Genzyme Corporation |
Anti-human cd52 immunoglobulins
|
|
CN102482345A
(zh)
|
2009-05-13 |
2012-05-30 |
航道生物技术有限责任公司 |
针对流感病毒的中和分子
|
|
BRPI1010620B8
(pt)
|
2009-06-03 |
2021-05-25 |
Immunogen Inc |
métodos de conjugação
|
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
AR078471A1
(es)
|
2009-10-02 |
2011-11-09 |
Sanofi Aventis |
COMPUESTOS MAITANSINOIDES Y EL USO DE ESTOS PARA PREPARAR CONJUGADOS CON UN ANTICUERPO LOS CUALES SE UTILIZAN COMO AGENTES ANTICANCERIGENOS Y EL PROCEDIMIENTO DE PREPARACIoN DE ESTOS CONJUGADOS
|
|
TW201116297A
(en)
|
2009-10-02 |
2011-05-16 |
Sanofi Aventis |
Antibodies that specifically bind to the EphA2 receptor
|
|
EP2486023A4
(en)
|
2009-10-06 |
2014-05-07 |
Immunogen Inc |
EFFICIENT CONJUGATES AND HYDROPHILIC BINDER
|
|
WO2011044563A2
(en)
|
2009-10-10 |
2011-04-14 |
The Board Of Trustees Of The Leland Stanford Junior University |
Il-17 family cytokine compositions and uses
|
|
MY173390A
(en)
|
2009-10-23 |
2020-01-22 |
Takeda Pharmaceuticals Co |
Anti-gcc antibody molecules and related compositions and methods
|
|
US20110165155A1
(en)
|
2009-12-04 |
2011-07-07 |
Genentech, Inc. |
Methods of treating metastatic breast cancer with trastuzumab-mcc-dm1
|
|
TW201129384A
(en)
|
2010-02-10 |
2011-09-01 |
Immunogen Inc |
CD20 antibodies and uses thereof
|
|
CN103037900B
(zh)
|
2010-02-24 |
2016-04-06 |
伊缪诺金公司 |
叶酸受体1抗体与免疫缀合物以及其用途
|
|
JP5998060B2
(ja)
|
2010-03-04 |
2016-09-28 |
マクロジェニクス，インコーポレーテッド |
Ｂ７−ｈ３と反応性のある抗体、その免疫学的に活性なフラグメントおよびその使用
|
|
SG183542A1
(en)
|
2010-03-12 |
2012-10-30 |
Immunogen Inc |
Cd37-binding molecules and immunoconjugates thereof
|
|
PT2552959T
(pt)
|
2010-03-26 |
2017-04-21 |
Memorial Sloan Kettering Cancer Center |
Anticorpos para muc16 e métodos de utilização dos mesmos
|
|
WO2011133555A2
(en)
|
2010-04-20 |
2011-10-27 |
The Research Foundation Of State University Of New York |
Compositions and methods for inhibiting matrix metalloproteinase (mmp)-mediated cell migration
|
|
EP3029066B1
(en)
|
2010-07-29 |
2019-02-20 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
|
WO2012019024A2
(en)
|
2010-08-04 |
2012-02-09 |
Immunogen, Inc. |
Her3-binding molecules and immunoconjugates thereof
|
|
EP3828205A1
(en)
|
2010-10-01 |
2021-06-02 |
Oxford BioTherapeutics Ltd |
Anti-ror1 antibodies
|
|
CN103298489A
(zh)
|
2010-10-29 |
2013-09-11 |
伊缪诺金公司 |
新型egfr结合分子及其免疫偶联物
|
|
CN105399831A
(zh)
|
2010-10-29 |
2016-03-16 |
伊缪诺金公司 |
非拮抗性egfr结合分子及其免疫偶联物
|
|
ES2931477T3
(es)
|
2010-10-29 |
2022-12-29 |
Perseus Proteomics Inc |
Anticuerpo anti-CDH3 que tiene alta capacidad de internalización
|
|
JP5889912B2
(ja)
|
2010-11-17 |
2016-03-22 |
ジェネンテック， インコーポレイテッド |
アラニニルメイタンシノール抗体コンジュゲート
|
|
WO2012075173A2
(en)
|
2010-12-01 |
2012-06-07 |
Board Of Regents The University Of Texas System |
Compositions and method for deimmunization of proteins
|
|
JOP20210044A1
(ar)
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
الأجسام المضادة لـ cd38
|
|
US9433686B2
(en)
|
2011-01-31 |
2016-09-06 |
The Regents Of The University Of California |
Methods for treating castration resistant prostate cancer and metastasis by reducing B-cell number and/or function
|
|
US20130344074A1
(en)
|
2011-03-16 |
2013-12-26 |
Sanofi |
Uses of a dual v region antibody-like protein
|
|
WO2012135517A2
(en)
|
2011-03-29 |
2012-10-04 |
Immunogen, Inc. |
Preparation of maytansinoid antibody conjugates by a one-step process
|
|
RS58367B1
(sr)
|
2011-03-29 |
2019-03-29 |
Immunogen Inc |
Priprema konjugata antitela i majtanzinoida jednostepenim postupkom
|
|
DK2714733T3
(da)
|
2011-05-21 |
2019-05-06 |
Macrogenics Inc |
Cd3-bindende molekyler, der er i stand til at binde til human og ikke-human cd3
|
|
WO2012171020A1
(en)
|
2011-06-10 |
2012-12-13 |
Mersana Therapeutics, Inc. |
Protein-polymer-drug conjugates
|
|
CN103648532A
(zh)
|
2011-06-21 |
2014-03-19 |
伊缪诺金公司 |
具有肽连接子的新型美登木素生物碱衍生物及其偶联物
|
|
US9738707B2
(en)
|
2011-07-15 |
2017-08-22 |
Biogen Ma Inc. |
Heterodimeric Fc regions, binding molecules comprising same, and methods relating thereto
|
|
WO2013016714A1
(en)
|
2011-07-28 |
2013-01-31 |
Sea Lane Biotechnologies |
Sur-binding proteins against erbb3
|
|
WO2013022855A1
(en)
|
2011-08-05 |
2013-02-14 |
Xencor, Inc. |
Antibodies with modified isoelectric points and immunofiltering
|
|
SG11201400859SA
(en)
|
2011-09-22 |
2014-04-28 |
Amgen Inc |
Cd27l antigen binding proteins
|
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
US12466897B2
(en)
|
2011-10-10 |
2025-11-11 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
WO2013055809A1
(en)
|
2011-10-10 |
2013-04-18 |
Xencor, Inc. |
A method for purifying antibodies
|
|
US9233171B2
(en)
|
2011-11-21 |
2016-01-12 |
Immunogen, Inc. |
Method of treatment of tumors that are resistant to EGFR antibody therapies by EGFR antibody cytotoxic agent conjugate
|
|
MX358680B
(es)
|
2011-12-08 |
2018-08-31 |
Biotest Ag |
Usos de inmunoconjugados dirigidos a cd138.
|
|
EP3446707A1
(en)
|
2011-12-22 |
2019-02-27 |
i2 Pharmaceuticals, Inc. |
Surrogate binding proteins
|
|
HK1204445A1
(en)
|
2012-01-20 |
2015-11-20 |
Sea Lane Biotechnologies, Llc |
Surrobody cojugates
|
|
US9592289B2
(en)
|
2012-03-26 |
2017-03-14 |
Sanofi |
Stable IgG4 based binding agent formulations
|
|
AR090549A1
(es)
|
2012-03-30 |
2014-11-19 |
Genentech Inc |
Anticuerpos anti-lgr5 e inmunoconjugados
|
|
EP2848686B1
(en)
|
2012-04-04 |
2024-12-25 |
Perseus Proteomics Inc. |
Conjugate of anti-cdh3 (p-cadherin) antibody and drug
|
|
US9156915B2
(en)
|
2012-04-26 |
2015-10-13 |
Thomas Jefferson University |
Anti-GCC antibody molecules
|
|
AU2013256596A1
(en)
|
2012-05-01 |
2014-10-09 |
Genentech, Inc. |
Anti-PMEL17 antibodies and immunoconjugates
|
|
AR091069A1
(es)
|
2012-05-18 |
2014-12-30 |
Amgen Inc |
Proteinas de union a antigeno dirigidas contra el receptor st2
|
|
IN2015KN00329A
(https=)
|
2012-08-09 |
2015-07-10 |
Univ Leland Stanford Junior |
|
|
WO2014055877A1
(en)
|
2012-10-04 |
2014-04-10 |
Immunogen, Inc. |
Use of a pvdf membrane to purify cell-binding agent cytotoxic agent conjugates
|
|
HUE033369T2
(en)
|
2012-11-20 |
2017-11-28 |
Sanofi Sa |
Anti-ceacam5 antibodies and uses thereof
|
|
US10131682B2
(en)
|
2012-11-24 |
2018-11-20 |
Hangzhou Dac Biotech Co., Ltd. |
Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules
|
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Ｂｃｍａ抗原結合蛋白質
|
|
US10226535B2
(en)
|
2012-12-10 |
2019-03-12 |
Mersana Therapeutics, Inc. |
Auristatin compounds and conjugates thereof
|
|
CA2892863C
(en)
|
2012-12-10 |
2022-03-15 |
Mersana Therapeutics, Inc. |
Polymeric scaffold based on phf for targeted drug delivery
|
|
WO2014093640A1
(en)
|
2012-12-12 |
2014-06-19 |
Mersana Therapeutics,Inc. |
Hydroxy-polmer-drug-protein conjugates
|
|
CN104530235A
(zh)
|
2012-12-21 |
2015-04-22 |
百奥泰生物科技(广州)有限公司 |
一种抑制肿瘤生长的抗体药物衍生物及其制备方法和用途
|
|
CN103333246B
(zh)
|
2012-12-21 |
2015-09-16 |
百奥泰生物科技(广州)有限公司 |
一种抗egfr受体的肿瘤生长抑制剂及其制备方法和用途
|
|
CN104688740A
(zh)
|
2012-12-21 |
2015-06-10 |
百奥泰生物科技(广州)有限公司 |
类美登素衍生物及其制备方法和用途
|
|
CN103254213B
(zh)
|
2012-12-21 |
2015-02-25 |
百奥泰生物科技(广州)有限公司 |
类美登素酯的制备方法及用于所述方法的组合物
|
|
ES2871816T3
(es)
|
2012-12-27 |
2021-11-02 |
Sanofi Sa |
Anticuerpos anti-LAMP1 y conjugados anticuerpo-fármaco, y usos de los mismos
|
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
CA2898100C
(en)
|
2013-01-14 |
2023-10-10 |
Xencor, Inc. |
Novel heterodimeric proteins
|
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
|
US9738722B2
(en)
|
2013-01-15 |
2017-08-22 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
|
EP2948478B1
(en)
|
2013-01-25 |
2019-04-03 |
Amgen Inc. |
Antibodies targeting cdh19 for melanoma
|
|
WO2014126198A1
(ja)
|
2013-02-15 |
2014-08-21 |
株式会社ペルセウスプロテオミクス |
抗ｃｄｈ３ヒト化抗体、その薬剤コンジュゲート、及びそれらの使用
|
|
US9562099B2
(en)
|
2013-03-14 |
2017-02-07 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
AU2014244424A1
(en)
|
2013-03-14 |
2015-08-27 |
Genentech, Inc. |
Anti-B7-H4 antibodies and immunoconjugates
|
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
|
AR095199A1
(es)
|
2013-03-15 |
2015-09-30 |
Genzyme Corp |
Anticuerpos anti-cd52
|
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
|
CA2902739C
(en)
|
2013-03-15 |
2022-11-22 |
Xencor, Inc. |
Heterodimeric proteins
|
|
EP2970486B1
(en)
|
2013-03-15 |
2018-05-16 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
|
CN108721295B
(zh)
|
2013-05-10 |
2021-05-04 |
高等教育联邦系统-匹兹堡大学 |
肺病症和其他病症的治疗
|
|
SI3456743T1
(sl)
|
2013-05-30 |
2022-01-31 |
Kiniksa Pharmaceuticals, Ltd. |
Proteini, ki vežejo antigen receptorja onkostatina M
|
|
WO2015042108A1
(en)
|
2013-09-17 |
2015-03-26 |
Genentech, Inc. |
Methods of using anti-lgr5 antibodies
|
|
IL298044B2
(en)
|
2013-10-08 |
2024-11-01 |
Immunogen Inc |
Dosing regimens of anti-FOLR1 immunoconjugate
|
|
EA032231B1
(ru)
|
2013-10-11 |
2019-04-30 |
Мерсана Терапьютикс, Инк. |
Конъюгаты белок-полимер-лекарственное средство
|
|
SI3055331T1
(sl)
|
2013-10-11 |
2021-04-30 |
Oxford Bio Therapeutics Limited |
Konjugirana protitelesa proti LY75 za zdravljenje raka
|
|
CA2927022C
(en)
|
2013-10-11 |
2018-08-21 |
Asana Biosciences, Llc |
Protein-polymer-drug conjugates
|
|
EA201691214A1
(ru)
|
2013-12-13 |
2016-12-30 |
Дженентек, Инк. |
Антитела к cd33 и иммуноконъюгаты
|
|
KR20170042495A
(ko)
|
2013-12-16 |
2017-04-19 |
제넨테크, 인크. |
펩티드모방체 화합물 및 그의 항체-약물 접합체
|
|
TWI541022B
(zh)
|
2013-12-18 |
2016-07-11 |
應克隆公司 |
針對纖維母細胞生長因子受體－３（ｆｇｆｒ３）之化合物及治療方法
|
|
US9943606B2
(en)
|
2014-01-15 |
2018-04-17 |
Rutgers, The State University Of New Jersey |
Dendritic polypeptide-based nanocarriers for the delivery of therapeutic agents
|
|
US20170043034A1
(en)
|
2014-01-24 |
2017-02-16 |
Genentech, Inc. |
Methods of using anti-steap1 antibodies and immunoconjugates
|
|
KR20160135190A
(ko)
|
2014-02-14 |
2016-11-25 |
앤드류 에스. 카이 |
혈관형성 암의 치료를 위한 개선된 방법
|
|
CA2938919C
(en)
|
2014-02-28 |
2020-12-29 |
Hangzhou Dac Biotech Co., Ltd |
Charged linkers and their uses for conjugation
|
|
NZ724904A
(en)
|
2014-03-14 |
2023-04-28 |
Biomolecular Holdings Llc |
Hybrid immunoglobulin containing non-peptidyl linkage
|
|
JP6775422B2
(ja)
|
2014-03-28 |
2020-10-28 |
ゼンコー・インコーポレイテッドＸｅｎｃｏｒ、 Ｉｎｃ． |
Ｃｄ３８及びｃｄ３に結合する二重特異性抗体
|
|
WO2015179658A2
(en)
|
2014-05-22 |
2015-11-26 |
Genentech, Inc. |
Anti-gpc3 antibodies and immunoconjugates
|
|
US20160060360A1
(en)
|
2014-07-24 |
2016-03-03 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
|
KR20170040249A
(ko)
|
2014-08-12 |
2017-04-12 |
노파르티스 아게 |
항-cdh6 항체 약물 접합체
|
|
WO2016033331A1
(en)
|
2014-08-28 |
2016-03-03 |
Bioatla, Llc |
Conditionally active chimeric antigen receptors for modified t-cells
|
|
CN106999604B
(zh)
|
2014-09-02 |
2021-08-03 |
伊缪诺金公司 |
用于配制抗体药物缀合物组合物的方法
|
|
JP6943760B2
(ja)
|
2014-09-12 |
2021-10-06 |
ジェネンテック， インコーポレイテッド |
抗ｂ７−ｈ４抗体及び免疫複合体
|
|
KR20170066421A
(ko)
|
2014-09-12 |
2017-06-14 |
제넨테크, 인크. |
항-cll-1 항체 및 면역접합체
|
|
PT3262071T
(pt)
|
2014-09-23 |
2020-06-16 |
H Hoffnabb La Roche Ag |
Métodos de utilização de imunoconjugados anti-cd79b
|
|
CN105585579A
(zh)
*
|
2014-10-24 |
2016-05-18 |
南京联宁生物制药有限公司 |
一种化合物及其制备方法以及美登素dm1的制备方法
|
|
WO2016075670A1
(en)
|
2014-11-14 |
2016-05-19 |
Novartis Ag |
Antibody drug conjugates
|
|
EP3220959A1
(en)
|
2014-11-19 |
2017-09-27 |
ImmunoGen, Inc. |
Process for preparing cell-binding agent-cytotoxic agent conjugates
|
|
CN110894240B
(zh)
|
2014-11-26 |
2022-04-15 |
森科股份有限公司 |
结合cd3和肿瘤抗原的异二聚体抗体
|
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
|
BR112017011166A2
(pt)
|
2014-11-26 |
2018-02-27 |
Xencor, Inc. |
anticorpos heterodiméricos que se ligam a cd3 e cd38
|
|
WO2016090157A1
(en)
|
2014-12-04 |
2016-06-09 |
Celgene Corporation |
Biomolecule conjugates
|
|
WO2016105450A2
(en)
|
2014-12-22 |
2016-06-30 |
Xencor, Inc. |
Trispecific antibodies
|
|
WO2016141387A1
(en)
|
2015-03-05 |
2016-09-09 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
|
JP6649961B2
(ja)
|
2015-03-17 |
2020-02-19 |
レゲネロン ファーマシューティカルス，インコーポレーテッド |
アミノ酸アシル化試薬及びその使用方法
|
|
WO2016149485A1
(en)
|
2015-03-17 |
2016-09-22 |
The Regents Of The University Of California |
Novel chemoimmunotherapy for epithelial cancer
|
|
CN107667120B
(zh)
|
2015-03-17 |
2022-03-08 |
纪念斯隆-凯特林癌症中心 |
抗muc16抗体及其应用
|
|
TW201711702A
(zh)
|
2015-06-04 |
2017-04-01 |
應克隆公司 |
使用針對纖維母細胞生長因子受體３（ｆｇｆｒ３）之化合物的療法
|
|
SG10202108116SA
(en)
|
2015-06-08 |
2021-08-30 |
Debiopharm International S A |
Anti-cd37 immunoconjugate and anti-cd20 antibody combinations
|
|
FI3319936T3
(fi)
|
2015-07-12 |
2026-03-12 |
Hangzhou Dac Biotech Co Ltd |
Silloituslinkkereitä soluun sitoutuvien molekyylien konjugoimiseksi
|
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
|
EP3331569A1
(en)
|
2015-08-07 |
2018-06-13 |
Gamamabs Pharma |
Antibodies, antibody drug conjugates and methods of use
|
|
AU2016323968B2
(en)
|
2015-09-17 |
2023-07-06 |
Immunogen, Inc. |
Therapeutic combinations comprising anti-FOLR1 immunoconjugates
|
|
JP7058219B2
(ja)
|
2015-12-07 |
2022-04-21 |
ゼンコア インコーポレイテッド |
Ｃｄ３及びｐｓｍａに結合するヘテロ二量体抗体
|
|
SG11201806478PA
(en)
|
2016-02-05 |
2018-08-30 |
Immunogen Inc |
Efficient process for preparing cell-binding agent-cytotoxic agent conjugates
|
|
PL3443012T3
(pl)
|
2016-04-15 |
2026-04-20 |
Bioatla, Inc. |
Przeciwciała anty-axl, fragmenty przeciwciał i ich immunokoniugaty oraz ich zastosowania
|
|
TW201808336A
(zh)
|
2016-05-11 |
2018-03-16 |
賽諾菲公司 |
用抗ｍｕｃ１類美登素免疫綴合物抗體治療腫瘤的治療方案
|
|
CN116751298A
(zh)
|
2016-05-13 |
2023-09-15 |
生物蛋白有限公司 |
抗ror2抗体、抗体片段和它们的免疫缀合物以及其用途
|
|
EP3465221B1
(en)
|
2016-05-27 |
2020-07-22 |
H. Hoffnabb-La Roche Ag |
Bioanalytical method for the characterization of site-specific antibody-drug conjugates
|
|
SI3468586T1
(sl)
|
2016-06-14 |
2025-01-31 |
Xencor, Inc. |
Bispecifična protitelesa za zaviralce kontrolnih točk
|
|
US11617799B2
(en)
|
2016-06-27 |
2023-04-04 |
Tagworks Pharmaceuticals B.V. |
Cleavable tetrazine used in bio-orthogonal drug activation
|
|
WO2018005706A1
(en)
|
2016-06-28 |
2018-01-04 |
Xencor, Inc. |
Heterodimeric antibodies that bind somatostatin receptor 2
|
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
CN110214147A
(zh)
|
2016-10-14 |
2019-09-06 |
Xencor股份有限公司 |
IL15/IL15Rα异源二聚体FC-融合蛋白
|
|
US11278629B2
(en)
|
2016-11-02 |
2022-03-22 |
Debiopharm International, S.A. |
Methods for improving anti-CD37 immunoconjugate therapy
|
|
CA3042442C
(en)
|
2016-11-14 |
2024-01-02 |
Hangzhou Dac Biotech Co., Ltd |
Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses of such conjugates with the linkers
|
|
JP7313684B2
(ja)
|
2016-11-21 |
2023-07-25 |
キュレアブ ゲーエムベーハー |
抗ｇｐ７３抗体及びイムノコンジュゲート
|
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
|
GB201703876D0
(en)
|
2017-03-10 |
2017-04-26 |
Berlin-Chemie Ag |
Pharmaceutical combinations
|
|
JP7320458B2
(ja)
|
2017-06-22 |
2023-08-03 |
メルサナ セラピューティクス インコーポレイテッド |
薬物担持ポリマースキャフォールドおよびタンパク質－ポリマー－薬物コンジュゲートを製造する方法
|
|
US11084863B2
(en)
|
2017-06-30 |
2021-08-10 |
Xencor, Inc. |
Targeted heterodimeric Fc fusion proteins containing IL-15 IL-15alpha and antigen binding domains
|
|
CN111225688B
(zh)
|
2017-08-22 |
2025-06-17 |
普渡研究基金会 |
靶向碳酸酐酶阳性癌症的基于fbsa的治疗和放射性成像缀合物
|
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
JP2021502100A
(ja)
|
2017-11-08 |
2021-01-28 |
ゼンコア インコーポレイテッド |
新規抗ｐｄ−１配列を用いた二重特異性および単一特異性抗体
|
|
WO2019108863A1
(en)
|
2017-11-29 |
2019-06-06 |
Magenta Therapeutics, Inc. |
Compositions and methods for the depletion of cd5+ cells
|
|
US11319355B2
(en)
|
2017-12-19 |
2022-05-03 |
Xencor, Inc. |
Engineered IL-2 Fc fusion proteins
|
|
KR20200123155A
(ko)
|
2018-02-21 |
2020-10-28 |
셀진 코포레이션 |
Bcma-결합 항체 및 이의 용도
|
|
WO2019195623A2
(en)
|
2018-04-04 |
2019-10-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
|
SG11202010163QA
(en)
|
2018-04-18 |
2020-11-27 |
Xencor Inc |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
|
US11505595B2
(en)
|
2018-04-18 |
2022-11-22 |
Xencor, Inc. |
TIM-3 targeted heterodimeric fusion proteins containing IL-15/IL-15RA Fc-fusion proteins and TIM-3 antigen binding domains
|
|
ES2975330T3
(es)
|
2018-05-04 |
2024-07-04 |
Tagworks Pharmaceuticals B V |
Compuestos que comprenden un enlazador para aumentar la estabilidad del trans-cicloocteno
|
|
EP3787691A1
(en)
|
2018-05-04 |
2021-03-10 |
Tagworks Pharmaceuticals B.V. |
Tetrazines for high click conjugation yield in vivo and high click release yield
|
|
US12144818B2
(en)
|
2018-05-30 |
2024-11-19 |
Debiopharm International, S.A. |
Method for treating cancer in a human patient by administering an anti-CD37 immunoconjugate using various dosing regimens
|
|
GB201809746D0
(en)
|
2018-06-14 |
2018-08-01 |
Berlin Chemie Ag |
Pharmaceutical combinations
|
|
TW202519260A
(zh)
|
2018-07-02 |
2025-05-16 |
美商安進公司 |
抗steap1抗原結合蛋白
|
|
CA3107383A1
(en)
|
2018-07-23 |
2020-01-30 |
Magenta Therapeutics, Inc. |
Use of anti-cd5 antibody drug conjugate (adc) in allogeneic cell therapy
|
|
EP3861016A2
(en)
|
2018-10-03 |
2021-08-11 |
Xencor, Inc. |
Il-12 heterodimeric fc-fusion proteins
|
|
AU2019369340A1
(en)
|
2018-10-29 |
2021-05-20 |
Mersana Therapeutics, Inc. |
Cysteine engineered antibody-drug conjugates with peptide-containing linkers
|
|
WO2020161214A1
(en)
|
2019-02-07 |
2020-08-13 |
Sanofi |
Use of anti-ceacam5 immunoconjugates for treating lung cancer
|
|
EP3693023A1
(en)
|
2019-02-11 |
2020-08-12 |
Sanofi |
Use of anti-ceacam5 immunoconjugates for treating lung cancer
|
|
UA128825C2
(uk)
|
2019-03-01 |
2024-10-30 |
Ксенкор, Інк. |
Гетеродимерні антитіла, що зв'язують enpp3 та cd3
|
|
CN113825759B
(zh)
*
|
2019-03-01 |
2024-06-04 |
细胞基因公司 |
美登醇的制备
|
|
DK3956332T3
(da)
|
2019-04-18 |
2023-05-01 |
Indena Spa |
Diasteroselektiv fremgangsmåde til fremstilling af thiol- eller disulfid-holdige maytansionidestere og mellemprodukter deraf
|
|
KR20220007136A
(ko)
|
2019-05-14 |
2022-01-18 |
제넨테크, 인크. |
소포 림프종을 치료하기 위한 항-CD79b 면역접합체의 사용 방법
|
|
IL289094A
(en)
|
2019-06-17 |
2022-02-01 |
Tagworks Pharmaceuticals B V |
Tetrazines for increasing the speed and yield of the "click release" reaction
|
|
EP4382129A3
(en)
|
2019-06-17 |
2024-07-03 |
Tagworks Pharmaceuticals B.V. |
Compounds for fast and efficient click release
|
|
CN114945386A
(zh)
|
2019-10-18 |
2022-08-26 |
基因泰克公司 |
使用抗CD79b免疫缀合物治疗弥漫性大B细胞淋巴瘤的方法
|
|
EP4072540A4
(en)
|
2019-11-05 |
2024-03-27 |
University of Georgia Research Foundation, Inc. |
Functionally modified maytansinoids and compositions and methods of use thereof
|
|
US12473579B2
(en)
|
2019-11-29 |
2025-11-18 |
Microbiopharm Japan Co., Ltd. |
Method for enzymatically producing maytansinol
|
|
IL294321B1
(en)
|
2020-01-09 |
2026-04-01 |
Mersana Therapeutics Inc |
Antibody-drug conjugates are attached at a specific site with linkers that include peptides.
|
|
US20230151088A1
(en)
|
2020-04-24 |
2023-05-18 |
Sanofi |
Antitumor combinations containing anti-ceacam5 antibody conjugates and folfox
|
|
WO2021214222A1
(en)
|
2020-04-24 |
2021-10-28 |
Sanofi |
Antitumor combinations containing anti-ceacam5 antibody conjugates, trifluridine and tipiracil
|
|
WO2021214227A1
(en)
|
2020-04-24 |
2021-10-28 |
Sanofi |
Antitumor combinations containing anti-ceacam5 antibody conjugates and cetuximab
|
|
AU2021261553A1
(en)
|
2020-04-24 |
2023-01-05 |
Sanofi |
Antitumor combinations containing anti-CEACAM5 antibody conjugates and FOLFIFI
|
|
WO2021231976A1
(en)
|
2020-05-14 |
2021-11-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (psma) and cd3
|
|
EP4178624A2
(en)
|
2020-07-07 |
2023-05-17 |
Bionecure Therapeutics, Inc. |
Maytansinoids as adc payloads and their use for the treatment of cancer
|
|
CA3192204A1
(en)
|
2020-08-19 |
2022-02-24 |
Xencor, Inc. |
Anti-cd28 and/or anti-b7h3 compositions
|
|
US12564642B2
(en)
|
2020-11-10 |
2026-03-03 |
Sanofi |
CEACAM5 antibody-drug conjugate formulation
|
|
JP2024511319A
(ja)
|
2021-03-09 |
2024-03-13 |
ゼンコア インコーポレイテッド |
Ｃｄ３及びｃｌｄｎ６に結合するヘテロ二量体抗体
|
|
JP2024509274A
(ja)
|
2021-03-10 |
2024-02-29 |
ゼンコア インコーポレイテッド |
Ｃｄ３及びｇｐｃ３に結合するヘテロ二量体抗体
|
|
JP2024532537A
(ja)
|
2021-09-06 |
2024-09-05 |
ヴェラクサ バイオテック ゲーエムベーハー |
真核生物における遺伝暗号の拡張のための新規アミノアシルｔＲＮＡ合成酵素変異体
|
|
CN117980327A
(zh)
|
2021-11-03 |
2024-05-03 |
杭州多禧生物科技有限公司 |
抗体的特异性偶联
|
|
CA3237142A1
(en)
|
2021-11-05 |
2023-05-11 |
Sanofi |
Antitumor combinations containing anti-ceacam5 antibody-drug conjugates and anti-vegfr-2 antibodies
|
|
EP4433170A1
(en)
|
2021-11-18 |
2024-09-25 |
Oxford BioTherapeutics Ltd |
Pharmaceutical combinations
|
|
CA3238627A1
(en)
|
2021-11-25 |
2023-06-01 |
Christine Kohler |
Improved antibody-payload conjugates (apcs) prepared by site-specific conjugation utilizing genetic code expansion
|
|
ES3039688T3
(en)
|
2021-11-25 |
2025-10-23 |
Veraxa Biotech Gmbh |
Improved antibody-payload conjugates (apcs) prepared by site-specific conjugation utilizing genetic code expansion
|
|
KR20240112348A
(ko)
|
2021-12-02 |
2024-07-18 |
사노피 |
암 치료법에서 환자 선택을 위한 cea 검정
|
|
WO2023099682A1
(en)
|
2021-12-02 |
2023-06-08 |
Sanofi |
Ceacam5 adc–anti-pd1/pd-l1 combination therapy
|
|
KR20240119102A
(ko)
|
2021-12-08 |
2024-08-06 |
유럽피안 몰레큘러 바이올로지 래보러토리 |
표적화 접합체의 제조를 위한 친수성 테트라진-관능화 페이로드
|
|
EP4372000A3
(en)
|
2022-02-15 |
2024-07-17 |
Tagworks Pharmaceuticals B.V. |
Masked il12 protein
|
|
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(ja)
|
2022-07-15 |
2025-07-30 |
フィアン セラピューティクス エルティーディー |
抗体－薬物複合体
|
|
IL320221A
(en)
|
2022-10-12 |
2025-06-01 |
Tagworks Pharmaceuticals B V |
Strained bicyclo-nonanes
|
|
CN120569216A
(zh)
|
2023-01-20 |
2025-08-29 |
巴斯夫欧洲公司 |
稳定型生物聚合物组合物、其制造和用途
|
|
KR20250154496A
(ko)
|
2023-03-01 |
2025-10-28 |
사노피 |
Ceacam5를 발현하는 신경내분비암을 치료하기 위한 항-ceacam5 면역접합체의 용도
|
|
EP4427763A1
(en)
|
2023-03-06 |
2024-09-11 |
Sanofi |
Antitumor combinations containing anti-ceacam5 antibody-drug conjugates, anti-vegfr-2 antibodies and anti-pd1/pd-l1 antibodies
|
|
KR20250169530A
(ko)
|
2023-03-10 |
2025-12-03 |
태그웍스 파마슈티컬스 비.브이. |
개선된 t-링커를 갖는 트랜스-사이클로옥텐
|
|
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(ko)
|
2023-03-23 |
2025-12-03 |
사노피 |
암 치료법에서 환자 선택을 위한 CEACAM5 mRNA 검정
|
|
AU2024286132A1
(en)
|
2023-06-05 |
2026-01-22 |
Sanofi |
Antitumor combinations containing anti-ceacam5 antibody-drug conjugates, anti-pd1/pd-l1 antibodies and anti-ctla4 antibodies
|
|
AU2024300552A1
(en)
|
2023-07-27 |
2026-01-29 |
Veraxa Biotech Gmbh |
Hydrophilic trans-cyclooctene (hytco) compounds, constructs and conjugates containing the same
|
|
WO2025056807A1
(en)
|
2023-09-15 |
2025-03-20 |
Basf Se |
Stabilized biopolymer composition, their manufacture and use
|
|
WO2025094146A1
(en)
|
2023-11-02 |
2025-05-08 |
Immunogen Switzerland Gmbh |
Vasconstrictors for reducing ocular toxicity of antibody-maytansinoid conjugates
|
|
WO2025149667A1
(en)
|
2024-01-12 |
2025-07-17 |
Pheon Therapeutics Ltd |
Antibody drug conjugates and uses thereof
|
|
WO2025169012A1
(en)
|
2024-02-06 |
2025-08-14 |
Sanofi |
Methods of treating ceacam5-expressing cancers
|
|
WO2025174248A1
(en)
|
2024-02-16 |
2025-08-21 |
Tagworks Pharmaceuticals B.V. |
Trans-cyclooctenes with "or gate" release
|
|
WO2026043376A1
(en)
|
2024-08-22 |
2026-02-26 |
Tagworks Pharmaceuticals B.V. |
Trans-cyclooctene formulations
|
|
WO2026078060A1
(en)
|
2024-10-08 |
2026-04-16 |
Basf Se |
Tocopherol alkoxylates for biopolymer stabilization
|