DK2714733T3 - Cd3-bindende molekyler, der er i stand til at binde til human og ikke-human cd3 - Google Patents

Cd3-bindende molekyler, der er i stand til at binde til human og ikke-human cd3 Download PDF

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Publication number
DK2714733T3
DK2714733T3 DK12790075.1T DK12790075T DK2714733T3 DK 2714733 T3 DK2714733 T3 DK 2714733T3 DK 12790075 T DK12790075 T DK 12790075T DK 2714733 T3 DK2714733 T3 DK 2714733T3
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human
bind
binding molecules
molecules
binding
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DK12790075.1T
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Ling Huang
Leslie S Johnson
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Macrogenics Inc
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    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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DK12790075.1T 2011-05-21 2012-05-16 Cd3-bindende molekyler, der er i stand til at binde til human og ikke-human cd3 DK2714733T3 (da)

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Application Number Priority Date Filing Date Title
US201161488716P 2011-05-21 2011-05-21
US201161530353P 2011-09-01 2011-09-01
PCT/US2012/038219 WO2012162067A2 (en) 2011-05-21 2012-05-16 Cd3-binding molecules capable of binding to human and non-human cd3

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DK2714733T3 true DK2714733T3 (da) 2019-05-06

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US (4) US9587021B2 (da)
EP (2) EP3492494A1 (da)
JP (4) JP6141831B2 (da)
KR (2) KR20190105112A (da)
CN (3) CN107827985A (da)
AU (3) AU2012259161B2 (da)
BR (2) BR122016016837A2 (da)
CA (1) CA2836857C (da)
CL (3) CL2013003329A1 (da)
CO (1) CO6970560A2 (da)
CY (1) CY1122020T1 (da)
DK (1) DK2714733T3 (da)
EA (1) EA033677B1 (da)
EC (1) ECSP13013101A (da)
ES (1) ES2732213T3 (da)
HR (1) HRP20190756T1 (da)
HU (1) HUE044209T2 (da)
IL (3) IL229575B (da)
LT (1) LT2714733T (da)
MA (1) MA35174B1 (da)
ME (1) ME03440B (da)
MX (1) MX369220B (da)
MY (1) MY173899A (da)
NZ (1) NZ703939A (da)
PL (1) PL2714733T3 (da)
PT (1) PT2714733T (da)
RS (1) RS58765B1 (da)
SG (3) SG10201703425RA (da)
SI (1) SI2714733T1 (da)
UA (3) UA117072C2 (da)
WO (1) WO2012162067A2 (da)
ZA (1) ZA201308602B (da)

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US9963510B2 (en) 2005-04-15 2018-05-08 Macrogenics, Inc. Covalent diabodies and uses thereof
CN101874042B9 (zh) 2007-09-26 2019-01-01 中外制药株式会社 利用cdr的氨基酸取代来改变抗体等电点的方法
LT2708559T (lt) 2008-04-11 2018-06-11 Chugai Seiyaku Kabushiki Kaisha Antigeną surišanti molekulė, galinti pakartotinai prisijungti prie dviejų ar daugiau antigeno molekulių
US9493578B2 (en) 2009-09-02 2016-11-15 Xencor, Inc. Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
AU2011283694B2 (en) 2010-07-29 2017-04-13 Xencor, Inc. Antibodies with modified isoelectric points
EP2647706B1 (en) 2010-11-30 2023-05-17 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly
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