IL158072A0 - Crystalline base of citalopram - Google Patents

Crystalline base of citalopram

Info

Publication number
IL158072A0
IL158072A0 IL15807201A IL15807201A IL158072A0 IL 158072 A0 IL158072 A0 IL 158072A0 IL 15807201 A IL15807201 A IL 15807201A IL 15807201 A IL15807201 A IL 15807201A IL 158072 A0 IL158072 A0 IL 158072A0
Authority
IL
Israel
Prior art keywords
citalopram
crystalline base
crystalline
base
Prior art date
Application number
IL15807201A
Other languages
English (en)
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8159320&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL158072(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of IL158072A0 publication Critical patent/IL158072A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Laminated Bodies (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
IL15807201A 2000-03-13 2001-02-28 Crystalline base of citalopram IL158072A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200000402 2000-03-13
DKPCT/DK00/00183 2000-04-13
IL14733901A IL147339A (en) 2000-03-13 2001-02-28 Preparation of crystalline base of citalopram and hydrochloride or hydrobromide salts
PCT/DK2001/000137 WO2001068627A1 (en) 2000-03-13 2001-02-28 Crystalline base of citalopram

Publications (1)

Publication Number Publication Date
IL158072A0 true IL158072A0 (en) 2004-03-28

Family

ID=8159320

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15807201A IL158072A0 (en) 2000-03-13 2001-02-28 Crystalline base of citalopram
IL14733901A IL147339A (en) 2000-03-13 2001-02-28 Preparation of crystalline base of citalopram and hydrochloride or hydrobromide salts

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL14733901A IL147339A (en) 2000-03-13 2001-02-28 Preparation of crystalline base of citalopram and hydrochloride or hydrobromide salts

Country Status (41)

Country Link
US (7) US20010031784A1 (cs)
EP (2) EP1227088B1 (cs)
JP (1) JP2003527383A (cs)
KR (1) KR20020080486A (cs)
CN (2) CN1258530C (cs)
AR (1) AR029811A1 (cs)
AT (3) ATE223396T1 (cs)
AU (2) AU746664B2 (cs)
BE (1) BE1013210A3 (cs)
BG (1) BG107065A (cs)
BR (1) BR0109373A (cs)
CA (2) CA2360287C (cs)
CH (2) CH691477A5 (cs)
CZ (1) CZ292077B6 (cs)
DE (7) DE20007303U1 (cs)
DK (3) DK173903B1 (cs)
EA (1) EA200200972A1 (cs)
ES (3) ES2180471T3 (cs)
FI (2) FI20010156A0 (cs)
FR (1) FR2806086B1 (cs)
GB (2) GB2357762B (cs)
GR (1) GR1003796B (cs)
HR (1) HRP20020756A2 (cs)
HU (3) HU0001581D0 (cs)
IE (1) IES20010109A2 (cs)
IL (2) IL158072A0 (cs)
IS (1) IS5841A (cs)
IT (2) IT1319645B1 (cs)
MX (1) MXPA02008793A (cs)
NL (2) NL1016435C1 (cs)
NO (2) NO312031B1 (cs)
PL (1) PL360158A1 (cs)
PT (2) PT1227088E (cs)
SE (2) SE517136C2 (cs)
SI (2) SI1227088T1 (cs)
SK (1) SK285528B6 (cs)
TR (1) TR200202185T2 (cs)
UA (1) UA74360C2 (cs)
WO (1) WO2001068627A1 (cs)
YU (1) YU68802A (cs)
ZA (1) ZA200207148B (cs)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA01010134A (es) * 1999-04-14 2002-04-15 Lundbeck & Co As H Metodo para la preparacion de citalopram.
AR021155A1 (es) * 1999-07-08 2002-06-12 Lundbeck & Co As H Tratamiento de desordenes neuroticos
US8328829B2 (en) 1999-08-19 2012-12-11 Covidien Lp High capacity debulking catheter with razor edge cutting window
US7713279B2 (en) 2000-12-20 2010-05-11 Fox Hollow Technologies, Inc. Method and devices for cutting tissue
US7708749B2 (en) 2000-12-20 2010-05-04 Fox Hollow Technologies, Inc. Debulking catheters and methods
US7887556B2 (en) 2000-12-20 2011-02-15 Fox Hollow Technologies, Inc. Debulking catheters and methods
US6299622B1 (en) 1999-08-19 2001-10-09 Fox Hollow Technologies, Inc. Atherectomy catheter with aligned imager
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US6977306B2 (en) 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IS6021A (is) * 2000-08-10 2001-10-20 H. Lundbeck A/S Lyfjasamsetningar sem innihalda sítalópram
GB2376233B (en) * 2000-08-10 2003-09-10 Lundbeck & Co As H Crystals of a pharmaceutically acceptable salt of citalopram wherein the median size of the crystals is at least 40 microns
EP2353526B1 (en) 2000-12-20 2013-09-04 Covidien LP Catheter for removing atheromatous or thrombotic occlusive material
CN1282648C (zh) * 2000-12-22 2006-11-01 H·隆德贝克有限公司 制备纯西酞普兰的方法
AU2001100195B4 (en) * 2001-01-05 2001-12-20 H Lundbeck As Pharmaceutical composition containing citalopram.
GB0105627D0 (en) * 2001-03-07 2001-04-25 Cipla Ltd Preparation of phthalanes
IL158031A0 (en) * 2001-05-01 2004-03-28 Lundbeck & Co As H The use of enantiomeric pure escitalopram
ATE352546T1 (de) 2001-07-31 2007-02-15 Lundbeck & Co As H Kristalline zusammensetzung enthaltend escitalopram
US7148364B2 (en) * 2002-01-07 2006-12-12 Sun Pharmaceutical Industries Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile
GB2386119A (en) * 2002-02-27 2003-09-10 Cipla Ltd Purification of citalopram
GB2387844B (en) * 2002-02-27 2005-05-11 Matrix Lab Ltd Separation of impurities from a crude mixture of citalopram
GB0204607D0 (en) 2002-02-27 2002-04-10 Matrix Lab Ltd Process
GB2385848A (en) * 2002-02-27 2003-09-03 Cipla Ltd Citalopram salts
GB2386118A (en) * 2002-02-27 2003-09-10 Cipla Ltd Citalopram
EP1346989A1 (en) * 2002-03-21 2003-09-24 Jubilant Organosys Limited Improved process for the preparation of citalopram and its hydrobromide
GB0206708D0 (en) * 2002-03-21 2002-05-01 Cipla Ltd Pharmaceutical salts
US6812355B2 (en) 2002-10-22 2004-11-02 Sekhsaria Chemicals Limited Process for the manufacture of citalopram hydrobromide from 5-bromophthalide
AU2003223105A1 (en) * 2003-03-24 2004-10-18 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
AU2003238676A1 (en) * 2003-04-21 2004-11-19 Podile Khadgapathi An improved process for the preparation of citalopram hydrobromide
US8246640B2 (en) 2003-04-22 2012-08-21 Tyco Healthcare Group Lp Methods and devices for cutting tissue at a vascular location
US7019153B2 (en) 2003-06-10 2006-03-28 Sun Pharmaceutical Industries Limited Process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran acetamido-3-substituted-3-cephem-4-carboxylic acid
GB0317475D0 (en) * 2003-07-25 2003-08-27 Meditab Specialities Pvt Ltd Product
JP4025735B2 (ja) * 2003-08-21 2007-12-26 ローム アンド ハース カンパニー 水性系を処理する方法
GB0320312D0 (en) 2003-08-29 2003-10-01 Novartis Ag Purification process
CN100569765C (zh) * 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
ITTO20050301A1 (it) * 2005-05-05 2006-11-06 Errekappa Euroterapici Spa Formulazioni liquide orali contenenti citalopram
WO2006123243A2 (en) * 2005-05-20 2006-11-23 Aurobindo Pharma Limited Pharmaceutical dosage forms comprising escitalopram in form of granules
TWI347942B (en) * 2005-06-22 2011-09-01 Lundbeck & Co As H Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
CN101534808A (zh) 2005-06-27 2009-09-16 拜维尔实验室国际有限公司 丁氨苯丙酮盐的改良释放配制品
US20070276419A1 (en) 2006-05-26 2007-11-29 Fox Hollow Technologies, Inc. Methods and devices for rotating an active element and an energy emitter on a catheter
US8784440B2 (en) 2008-02-25 2014-07-22 Covidien Lp Methods and devices for cutting tissue
JP5555242B2 (ja) 2008-10-13 2014-07-23 コヴィディエン リミテッド パートナーシップ カテーテルシャフトを操作するデバイスおよび方法
US9687266B2 (en) 2009-04-29 2017-06-27 Covidien Lp Methods and devices for cutting and abrading tissue
AU2010248909B2 (en) 2009-05-14 2013-03-21 Covidien Lp Easily cleaned atherectomy catheters and methods of use
WO2011068932A1 (en) 2009-12-02 2011-06-09 Fox Hollow Technologies, Inc. Methods and devices for cutting tissue
KR101398384B1 (ko) 2009-12-11 2014-05-23 코비디엔 엘피 물질 포획 효율이 향상된 물질 제거 장치 및 사용 방법
CN102946815B (zh) 2010-06-14 2015-07-15 科维蒂恩有限合伙公司 材料移除装置
US8920450B2 (en) 2010-10-28 2014-12-30 Covidien Lp Material removal device and method of use
EP2637567B1 (en) 2010-11-11 2017-03-08 Covidien LP Flexible debulking catheters with imaging and methods of manufacture
JP5806407B2 (ja) 2011-09-01 2015-11-10 コヴィディエン リミテッド パートナーシップ 螺旋駆動軸を有するカテーテルおよび製造方法
US9579157B2 (en) 2012-09-13 2017-02-28 Covidien Lp Cleaning device for medical instrument and method of use
US9943329B2 (en) 2012-11-08 2018-04-17 Covidien Lp Tissue-removing catheter with rotatable cutter
WO2015200702A1 (en) 2014-06-27 2015-12-30 Covidien Lp Cleaning device for catheter and catheter including the same
US10314667B2 (en) 2015-03-25 2019-06-11 Covidien Lp Cleaning device for cleaning medical instrument
US10292721B2 (en) 2015-07-20 2019-05-21 Covidien Lp Tissue-removing catheter including movable distal tip
US10314664B2 (en) 2015-10-07 2019-06-11 Covidien Lp Tissue-removing catheter and tissue-removing element with depth stop
JP7739256B2 (ja) 2019-07-19 2025-09-16 バイオエクセル セラピューティクス,インコーポレイテッド 鎮静作用のないデクスメデトミジン治療レジメン
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (22)

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US2233970A (en) * 1941-03-04 Quinoline compound and process of
US2584429A (en) * 1950-12-29 1952-02-05 Rohm & Haas 1,1-diphenyl-4-tert.-amino-2-butyne-1-ols
GB1143702A (cs) * 1965-03-18
US4314081A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Arloxyphenylpropylamines
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
IL63968A (en) * 1980-10-01 1985-10-31 Glaxo Group Ltd Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it
US4535186A (en) * 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
DK213290D0 (da) 1990-09-06 1990-09-06 Lundbeck & Co As H Treatment of cerebrovascular disorders
US5296507A (en) * 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
CA2120874E (en) * 1994-04-08 2002-01-08 Keshava Murthy Form of form 1 ranitidine
DE69801764T2 (de) * 1997-07-08 2002-07-04 H. Lundbeck A/S, Kobenhavn-Valby Verfahren zur herstellung von citalopram
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
DE69714480T2 (de) * 1997-11-11 2003-03-06 Lundbeck & Co As H Verfahren zur Herstellung von Citalopram
IL142346A0 (en) 1998-10-20 2002-03-10 Lundbeck & Co As H Method for the preparation of citalopram
MXPA01010134A (es) 1999-04-14 2002-04-15 Lundbeck & Co As H Metodo para la preparacion de citalopram.
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
US6433196B1 (en) * 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US6977306B2 (en) * 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof

Also Published As

Publication number Publication date
SE0200730D0 (sv) 2002-03-12
ES2173054T3 (es) 2002-12-16
JP2003527383A (ja) 2003-09-16
AU3725201A (en) 2001-09-13
DK1227088T3 (da) 2003-12-22
AU2001100197B4 (en) 2001-12-06
TR200202185T2 (tr) 2002-12-23
FI20010156A0 (fi) 2001-01-25
WO2001068627A1 (en) 2001-09-20
EP1169314B2 (en) 2011-06-01
CH691537A5 (de) 2001-08-15
CA2411732A1 (en) 2001-09-20
AR029811A1 (es) 2003-07-16
SI1169314T1 (en) 2002-12-31
YU68802A (sh) 2005-11-28
EP1227088A1 (en) 2002-07-31
DE60100022T3 (de) 2011-11-17
NL1017413C1 (nl) 2001-09-13
FR2806086A1 (fr) 2001-09-14
US20030078442A1 (en) 2003-04-24
SI1227088T1 (en) 2003-12-31
ES2180471T1 (es) 2003-02-16
MXPA02008793A (es) 2003-02-12
GB2357762B (en) 2002-01-30
GB2357762A (en) 2001-07-04
HK1054750A1 (en) 2003-12-12
GB0102797D0 (en) 2001-03-21
CA2360287C (en) 2003-09-09
GB0105982D0 (en) 2001-05-02
SK285528B6 (sk) 2007-03-01
EP1169314B1 (en) 2002-09-04
BR0109373A (pt) 2002-12-24
DK1169314T3 (da) 2002-10-14
AT4364U1 (de) 2001-06-25
SE0103046D0 (sv) 2001-09-14
US20010031784A1 (en) 2001-10-18
EA200200972A1 (ru) 2003-02-27
DE60100022D1 (de) 2002-10-10
UA74360C2 (uk) 2005-12-15
US20050165092A1 (en) 2005-07-28
US20050165244A1 (en) 2005-07-28
US20060247451A1 (en) 2006-11-02
HRP20020756A2 (en) 2004-12-31
HU0001581D0 (en) 2000-06-28
SE0103046L (sv) 2001-11-14
NO20010619D0 (no) 2001-02-06
SI1169314T2 (sl) 2011-08-31
BG107065A (bg) 2003-05-30
EP1227088B1 (en) 2003-09-17
CH691477A5 (de) 2001-07-31
SE517136C2 (sv) 2002-04-16
KR20020080486A (ko) 2002-10-23
DE20007303U1 (de) 2000-07-27
ES2180471T3 (es) 2004-05-01
CN1258530C (zh) 2006-06-07
EP1169314A1 (en) 2002-01-09
HUP0100531A2 (hu) 2002-01-28
DE60100786T2 (de) 2004-07-15
IES20010109A2 (en) 2002-02-20
IS5841A (is) 2001-09-14
HU0100450D0 (en) 2001-04-28
FI20010225L (fi) 2001-09-14
ES2159491B1 (es) 2002-05-01
PT1227088E (pt) 2003-12-31
PL360158A1 (en) 2004-09-06
GR1003796B (el) 2002-02-08
CA2360287A1 (en) 2001-09-20
US20040167210A1 (en) 2004-08-26
CN1680350A (zh) 2005-10-12
CZ292077B6 (cs) 2003-07-16
HUP0100531A3 (en) 2004-04-28
AU2001100197A4 (en) 2001-09-20
ZA200207148B (en) 2003-04-23
DE10108042A1 (de) 2001-10-18
AU746664B2 (en) 2002-05-02
NO20020356L (no) 2001-09-14
ITMI20002425A1 (it) 2002-05-09
IL147339A (en) 2004-09-27
PT1169314E (pt) 2002-11-29
DE20121240U1 (de) 2002-07-04
FR2806086B1 (fr) 2003-05-09
SE0200730L (sv) 2002-08-29
IT1319645B1 (it) 2003-10-23
DE60100786D1 (de) 2003-10-23
NO312031B1 (no) 2002-03-04
SE526022C2 (sv) 2005-06-14
SK13132002A3 (sk) 2003-01-09
DK173903B1 (da) 2002-02-11
HU0100531D0 (en) 2001-03-28
DE10164687B4 (de) 2006-04-27
DE1227088T1 (de) 2003-02-06
ATE223396T1 (de) 2002-09-15
NO315851B1 (no) 2003-11-03
DE60100022T2 (de) 2003-03-06
NL1016435C1 (nl) 2000-11-06
FI20010225A0 (fi) 2001-02-07
NO20010619L (no) 2001-09-14
NO20020356D0 (no) 2002-01-23
CN1429220A (zh) 2003-07-09
FI109022B (fi) 2002-05-15
US20040132808A1 (en) 2004-07-08
ATE250050T1 (de) 2003-10-15
ITMI20010406A1 (it) 2002-08-28
BE1013210A3 (fr) 2001-10-02
CZ2001808A3 (cs) 2002-01-16
ES2173054T1 (es) 2002-10-16
IL147339A0 (en) 2002-08-14
ES2159491A1 (es) 2001-10-01

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