SE517136C2 - Kristallin bas av citalopram - Google Patents

Kristallin bas av citalopram

Info

Publication number
SE517136C2
SE517136C2 SE0103046A SE0103046A SE517136C2 SE 517136 C2 SE517136 C2 SE 517136C2 SE 0103046 A SE0103046 A SE 0103046A SE 0103046 A SE0103046 A SE 0103046A SE 517136 C2 SE517136 C2 SE 517136C2
Authority
SE
Sweden
Prior art keywords
citalopram
base
salt
crude
crystalline
Prior art date
Application number
SE0103046A
Other languages
English (en)
Swedish (sv)
Other versions
SE0103046D0 (sv
SE0103046L (sv
Inventor
Hans Petersen
Klaus Peter Boegesoe
Per Holm
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8159320&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE517136(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of SE0103046D0 publication Critical patent/SE0103046D0/xx
Publication of SE0103046L publication Critical patent/SE0103046L/xx
Publication of SE517136C2 publication Critical patent/SE517136C2/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Laminated Bodies (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
SE0103046A 2000-03-13 2001-09-14 Kristallin bas av citalopram SE517136C2 (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200000402 2000-03-13
DKPCT/DK00/00183 2000-04-13
PCT/DK2001/000137 WO2001068627A1 (en) 2000-03-13 2001-02-28 Crystalline base of citalopram

Publications (3)

Publication Number Publication Date
SE0103046D0 SE0103046D0 (sv) 2001-09-14
SE0103046L SE0103046L (sv) 2001-11-14
SE517136C2 true SE517136C2 (sv) 2002-04-16

Family

ID=8159320

Family Applications (2)

Application Number Title Priority Date Filing Date
SE0103046A SE517136C2 (sv) 2000-03-13 2001-09-14 Kristallin bas av citalopram
SE0200730A SE526022C2 (sv) 2000-03-13 2002-03-12 Kristallin bas av citalopram

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE0200730A SE526022C2 (sv) 2000-03-13 2002-03-12 Kristallin bas av citalopram

Country Status (41)

Country Link
US (7) US20010031784A1 (cs)
EP (2) EP1227088B1 (cs)
JP (1) JP2003527383A (cs)
KR (1) KR20020080486A (cs)
CN (2) CN1680350A (cs)
AR (1) AR029811A1 (cs)
AT (3) ATE223396T1 (cs)
AU (2) AU746664B2 (cs)
BE (1) BE1013210A3 (cs)
BG (1) BG107065A (cs)
BR (1) BR0109373A (cs)
CA (2) CA2411732A1 (cs)
CH (2) CH691537A5 (cs)
CZ (1) CZ292077B6 (cs)
DE (7) DE20007303U1 (cs)
DK (3) DK173903B1 (cs)
EA (1) EA200200972A1 (cs)
ES (3) ES2180471T3 (cs)
FI (2) FI20010156A0 (cs)
FR (1) FR2806086B1 (cs)
GB (2) GB2357762B (cs)
GR (1) GR1003796B (cs)
HR (1) HRP20020756A2 (cs)
HU (3) HU0001581D0 (cs)
IE (1) IES20010109A2 (cs)
IL (2) IL147339A (cs)
IS (1) IS5841A (cs)
IT (2) IT1319645B1 (cs)
MX (1) MXPA02008793A (cs)
NL (2) NL1016435C1 (cs)
NO (2) NO312031B1 (cs)
PL (1) PL360158A1 (cs)
PT (2) PT1227088E (cs)
SE (2) SE517136C2 (cs)
SI (2) SI1227088T1 (cs)
SK (1) SK285528B6 (cs)
TR (1) TR200202185T2 (cs)
UA (1) UA74360C2 (cs)
WO (1) WO2001068627A1 (cs)
YU (1) YU68802A (cs)
ZA (1) ZA200207148B (cs)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999030548A2 (en) * 1999-04-14 1999-06-24 H. Lundbeck A/S Method for the preparation of citalopram
AR021155A1 (es) * 1999-07-08 2002-06-12 Lundbeck & Co As H Tratamiento de desordenes neuroticos
US7887556B2 (en) 2000-12-20 2011-02-15 Fox Hollow Technologies, Inc. Debulking catheters and methods
US7708749B2 (en) 2000-12-20 2010-05-04 Fox Hollow Technologies, Inc. Debulking catheters and methods
US8328829B2 (en) 1999-08-19 2012-12-11 Covidien Lp High capacity debulking catheter with razor edge cutting window
US6299622B1 (en) 1999-08-19 2001-10-09 Fox Hollow Technologies, Inc. Atherectomy catheter with aligned imager
US7713279B2 (en) 2000-12-20 2010-05-11 Fox Hollow Technologies, Inc. Method and devices for cutting tissue
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US6977306B2 (en) 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
GB2376233B (en) * 2000-08-10 2003-09-10 Lundbeck & Co As H Crystals of a pharmaceutically acceptable salt of citalopram wherein the median size of the crystals is at least 40 microns
IS6021A (is) * 2000-08-10 2001-10-20 H. Lundbeck A/S Lyfjasamsetningar sem innihalda sítalópram
DE60144107D1 (de) 2000-12-20 2011-04-07 Fox Hollow Technologies Inc Verkleinerungskatheter
SK286283B6 (sk) * 2000-12-22 2008-06-06 H. Lundbeck A/S Spôsob výroby čisteného citalopramu
AU2001100195B4 (en) * 2001-01-05 2001-12-20 H Lundbeck As Pharmaceutical composition containing citalopram.
GB0105627D0 (en) * 2001-03-07 2001-04-25 Cipla Ltd Preparation of phthalanes
US20040198809A1 (en) * 2001-05-01 2004-10-07 Connie Sanchez Use of enantiomeric pure escitalopram
RS8304A (en) 2001-07-31 2006-12-15 H.Lundbeck A/S. Crystalline composition containing escitalopram
AU2003222435A1 (en) * 2002-01-07 2003-07-24 Sun Pharmaceutical Industries Limited Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
GB2386118A (en) * 2002-02-27 2003-09-10 Cipla Ltd Citalopram
GB2387844B (en) * 2002-02-27 2005-05-11 Matrix Lab Ltd Separation of impurities from a crude mixture of citalopram
GB2385848A (en) * 2002-02-27 2003-09-03 Cipla Ltd Citalopram salts
GB0204607D0 (en) 2002-02-27 2002-04-10 Matrix Lab Ltd Process
GB2386119A (en) * 2002-02-27 2003-09-10 Cipla Ltd Purification of citalopram
EP1346989A1 (en) * 2002-03-21 2003-09-24 Jubilant Organosys Limited Improved process for the preparation of citalopram and its hydrobromide
GB0206708D0 (en) * 2002-03-21 2002-05-01 Cipla Ltd Pharmaceutical salts
US6812355B2 (en) 2002-10-22 2004-11-02 Sekhsaria Chemicals Limited Process for the manufacture of citalopram hydrobromide from 5-bromophthalide
AU2003223105A1 (en) * 2003-03-24 2004-10-18 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
AU2003238676A1 (en) * 2003-04-21 2004-11-19 Podile Khadgapathi An improved process for the preparation of citalopram hydrobromide
US8246640B2 (en) 2003-04-22 2012-08-21 Tyco Healthcare Group Lp Methods and devices for cutting tissue at a vascular location
EP1486492A3 (en) * 2003-06-10 2005-02-23 Sun Pharmaceuticals Industries Ltd. A process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran.
GB0317475D0 (en) 2003-07-25 2003-08-27 Meditab Specialities Pvt Ltd Product
JP4025735B2 (ja) * 2003-08-21 2007-12-26 ローム アンド ハース カンパニー 水性系を処理する方法
GB0320312D0 (en) 2003-08-29 2003-10-01 Novartis Ag Purification process
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
ITTO20050301A1 (it) * 2005-05-05 2006-11-06 Errekappa Euroterapici Spa Formulazioni liquide orali contenenti citalopram
EP1901714A2 (en) * 2005-05-20 2008-03-26 Aurobindo Pharma Limited Pharmaceutical dosage forms comprising escitalopram in form of granules
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
TWI358407B (en) * 2005-06-22 2012-02-21 Lundbeck & Co As H Crystalline base of escitalopram and orodispersibl
KR101306635B1 (ko) 2005-06-27 2013-10-11 밸리언트 인터내셔널(바베이도스) 에스알엘 부프로피온염의 개질-방출 제형
US20070276419A1 (en) 2006-05-26 2007-11-29 Fox Hollow Technologies, Inc. Methods and devices for rotating an active element and an energy emitter on a catheter
US8784440B2 (en) 2008-02-25 2014-07-22 Covidien Lp Methods and devices for cutting tissue
JP5555242B2 (ja) 2008-10-13 2014-07-23 コヴィディエン リミテッド パートナーシップ カテーテルシャフトを操作するデバイスおよび方法
US9687266B2 (en) 2009-04-29 2017-06-27 Covidien Lp Methods and devices for cutting and abrading tissue
AU2010248909B2 (en) 2009-05-14 2013-03-21 Covidien Lp Easily cleaned atherectomy catheters and methods of use
KR20120079479A (ko) 2009-12-02 2012-07-12 타이코 헬스케어 그룹 엘피 조직 절단 장치 및 방법
KR101398384B1 (ko) 2009-12-11 2014-05-23 코비디엔 엘피 물질 포획 효율이 향상된 물질 제거 장치 및 사용 방법
WO2011159697A1 (en) 2010-06-14 2011-12-22 Tyco Healthcare Group Lp Material removal device
RU2539720C2 (ru) 2010-10-28 2015-01-27 Ковидиен Лп Устройство для удаления материала и способ применения
CA2817213C (en) 2010-11-11 2016-06-14 Covidien Lp Flexible debulking catheters with imaging and methods of use and manufacture
US8992717B2 (en) 2011-09-01 2015-03-31 Covidien Lp Catheter with helical drive shaft and methods of manufacture
US9532844B2 (en) 2012-09-13 2017-01-03 Covidien Lp Cleaning device for medical instrument and method of use
US9943329B2 (en) 2012-11-08 2018-04-17 Covidien Lp Tissue-removing catheter with rotatable cutter
WO2015200702A1 (en) 2014-06-27 2015-12-30 Covidien Lp Cleaning device for catheter and catheter including the same
US10314667B2 (en) 2015-03-25 2019-06-11 Covidien Lp Cleaning device for cleaning medical instrument
US10292721B2 (en) 2015-07-20 2019-05-21 Covidien Lp Tissue-removing catheter including movable distal tip
US10314664B2 (en) 2015-10-07 2019-06-11 Covidien Lp Tissue-removing catheter and tissue-removing element with depth stop
JP7739256B2 (ja) 2019-07-19 2025-09-16 バイオエクセル セラピューティクス，インコーポレイテッド 鎮静作用のないデクスメデトミジン治療レジメン
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

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US5296507A (en) * 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DK213290D0 (da) 1990-09-06 1990-09-06 Lundbeck & Co As H Treatment of cerebrovascular disorders
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PT1015416E (pt) * 1997-07-08 2002-03-28 Lundbeck & Co As H Metodo para a producao de citalopram
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
CN1286687A (zh) * 1997-11-11 2001-03-07 H·隆德贝克有限公司 制备西酞普兰的方法
JP3892667B2 (ja) * 1998-10-20 2007-03-14 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
WO1999030548A2 (en) 1999-04-14 1999-06-24 H. Lundbeck A/S Method for the preparation of citalopram
ITMI991579A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
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GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US6977306B2 (en) * 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof

Also Published As

Publication number Publication date
DE60100786D1 (de) 2003-10-23
BE1013210A3 (fr) 2001-10-02
NO312031B1 (no) 2002-03-04
US20040132808A1 (en) 2004-07-08
UA74360C2 (uk) 2005-12-15
US20050165092A1 (en) 2005-07-28
CZ292077B6 (cs) 2003-07-16
DE1227088T1 (de) 2003-02-06
FI20010225L (fi) 2001-09-14
CH691537A5 (de) 2001-08-15
DK173903B1 (da) 2002-02-11
SE526022C2 (sv) 2005-06-14
ES2159491A1 (es) 2001-10-01
CN1429220A (zh) 2003-07-09
CZ2001808A3 (cs) 2002-01-16
DE10108042A1 (de) 2001-10-18
US20040167210A1 (en) 2004-08-26
DE60100022T2 (de) 2003-03-06
HU0001581D0 (en) 2000-06-28
HU0100450D0 (en) 2001-04-28
EP1169314A1 (en) 2002-01-09
SK13132002A3 (sk) 2003-01-09
US20060247451A1 (en) 2006-11-02
CA2411732A1 (en) 2001-09-20
ITMI20002425A1 (it) 2002-05-09
SE0103046D0 (sv) 2001-09-14
AU2001100197B4 (en) 2001-12-06
DE20121240U1 (de) 2002-07-04
FI20010225A0 (fi) 2001-02-07
HUP0100531A3 (en) 2004-04-28
IT1319645B1 (it) 2003-10-23
MXPA02008793A (es) 2003-02-12
FR2806086A1 (fr) 2001-09-14
IL158072A0 (en) 2004-03-28
EP1169314B1 (en) 2002-09-04
GB0105982D0 (en) 2001-05-02
DE20007303U1 (de) 2000-07-27
US20050165244A1 (en) 2005-07-28
DE60100022T3 (de) 2011-11-17
CN1680350A (zh) 2005-10-12
AU3725201A (en) 2001-09-13
GR1003796B (el) 2002-02-08
GB0102797D0 (en) 2001-03-21
ZA200207148B (en) 2003-04-23
FI109022B (fi) 2002-05-15
SI1227088T1 (en) 2003-12-31
CH691477A5 (de) 2001-07-31
PT1169314E (pt) 2002-11-29
DK1227088T3 (da) 2003-12-22
NO20010619L (no) 2001-09-14
JP2003527383A (ja) 2003-09-16
GB2357762B (en) 2002-01-30
CN1258530C (zh) 2006-06-07
ES2180471T3 (es) 2004-05-01
FR2806086B1 (fr) 2003-05-09
BR0109373A (pt) 2002-12-24
SK285528B6 (sk) 2007-03-01
ITMI20010406A1 (it) 2002-08-28
US20030078442A1 (en) 2003-04-24
DE60100786T2 (de) 2004-07-15
EA200200972A1 (ru) 2003-02-27
ATE223396T1 (de) 2002-09-15
EP1169314B2 (en) 2011-06-01
YU68802A (sh) 2005-11-28
GB2357762A (en) 2001-07-04
SE0200730D0 (sv) 2002-03-12
FI20010156A0 (fi) 2001-01-25
HK1054750A1 (en) 2003-12-12
HRP20020756A2 (en) 2004-12-31
ATE250050T1 (de) 2003-10-15
TR200202185T2 (tr) 2002-12-23
EP1227088A1 (en) 2002-07-31
HU0100531D0 (en) 2001-03-28
NL1016435C1 (nl) 2000-11-06
IL147339A (en) 2004-09-27
ES2173054T3 (es) 2002-12-16
PL360158A1 (en) 2004-09-06
SE0103046L (sv) 2001-11-14
ES2159491B1 (es) 2002-05-01
DK1169314T3 (da) 2002-10-14
NO20020356D0 (no) 2002-01-23
AT4364U1 (de) 2001-06-25
IS5841A (is) 2001-09-14
SI1169314T1 (en) 2002-12-31
NL1017413C1 (nl) 2001-09-13
CA2360287C (en) 2003-09-09
ES2173054T1 (es) 2002-10-16
DE10164687B4 (de) 2006-04-27
IL147339A0 (en) 2002-08-14
CA2360287A1 (en) 2001-09-20
DE60100022D1 (de) 2002-10-10
HUP0100531A2 (hu) 2002-01-28
EP1227088B1 (en) 2003-09-17
PT1227088E (pt) 2003-12-31
BG107065A (bg) 2003-05-30
KR20020080486A (ko) 2002-10-23
NO20010619D0 (no) 2001-02-06
IES20010109A2 (en) 2002-02-20
AR029811A1 (es) 2003-07-16
SE0200730L (sv) 2002-08-29
AU2001100197A4 (en) 2001-09-20
SI1169314T2 (sl) 2011-08-31
ES2180471T1 (es) 2003-02-16
NO20020356L (no) 2001-09-14
NO315851B1 (no) 2003-11-03
WO2001068627A1 (en) 2001-09-20
US20010031784A1 (en) 2001-10-18
AU746664B2 (en) 2002-05-02

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