AR034898A1 - Composicion cristalina que contiene escitalopram - Google Patents

Composicion cristalina que contiene escitalopram

Info

Publication number
AR034898A1
AR034898A1 ARP020102808A ARP020102808A AR034898A1 AR 034898 A1 AR034898 A1 AR 034898A1 AR P020102808 A ARP020102808 A AR P020102808A AR P020102808 A ARP020102808 A AR P020102808A AR 034898 A1 AR034898 A1 AR 034898A1
Authority
AR
Argentina
Prior art keywords
composition containing
crystal composition
containing escitalopram
escitalopram
crystalline particles
Prior art date
Application number
ARP020102808A
Other languages
English (en)
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8160647&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR034898(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of AR034898A1 publication Critical patent/AR034898A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Partículas cristalinas de oxalato de escitalopram cuyas partículas tienen un tamano de por lo menos 40 microm. Método para la manufactura de dichas partículas cristalinas y composiciones farmacéuticas que contienen dichas partículas cristalinas.
ARP020102808A 2001-07-31 2002-07-25 Composicion cristalina que contiene escitalopram AR034898A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200101164 2001-07-31

Publications (1)

Publication Number Publication Date
AR034898A1 true AR034898A1 (es) 2004-03-24

Family

ID=8160647

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020102808A AR034898A1 (es) 2001-07-31 2002-07-25 Composicion cristalina que contiene escitalopram

Country Status (40)

Country Link
US (3) US6916941B2 (es)
EP (2) EP1414435B1 (es)
JP (4) JP2005525993A (es)
KR (1) KR20040028947A (es)
CN (2) CN1311819C (es)
AR (1) AR034898A1 (es)
AT (2) ATE286730T1 (es)
AU (1) AU2002355624B2 (es)
BG (1) BG108571A (es)
BR (1) BR0206164A (es)
CA (1) CA2451915C (es)
CO (1) CO5560540A2 (es)
CY (1) CY1106413T1 (es)
DE (2) DE60202615T2 (es)
DK (2) DK1522539T3 (es)
EA (1) EA006213B1 (es)
EG (1) EG24206A (es)
ES (2) ES2233842T3 (es)
HK (1) HK1070000A1 (es)
HR (2) HRP20031073A2 (es)
HU (1) HUP0401946A2 (es)
IL (2) IL159326A0 (es)
IS (1) IS7077A (es)
MA (1) MA27349A1 (es)
ME (1) MEP2108A (es)
MX (1) MXPA04000849A (es)
MY (1) MY126238A (es)
NO (1) NO328346B1 (es)
NZ (1) NZ530157A (es)
PE (1) PE20030304A1 (es)
PL (1) PL366995A1 (es)
PT (2) PT1522539E (es)
RS (1) RS8304A (es)
SI (1) SI1414435T1 (es)
TN (1) TNSN04021A1 (es)
TR (1) TR200400189T2 (es)
UA (1) UA79930C2 (es)
UY (1) UY27404A1 (es)
WO (1) WO2003011278A1 (es)
ZA (1) ZA200309684B (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9917346A (pt) 1999-04-14 2002-02-26 Lundbeck & Co As H Método para preparação de citalopram intermadiário e utilização do mesmo
US20030109577A1 (en) * 2000-10-27 2003-06-12 Ken Liljegren Pharmaceutical composition containing citalopram
US20030232881A1 (en) * 2000-10-27 2003-12-18 H. Lundbeck A/S Crystals of pharmaceutically acceptable salts of citalopram, methods of crystallization, and pharmaceutical compositions comprising them
DK1522539T3 (da) 2001-07-31 2007-05-07 Lundbeck & Co As H Krystallinsk komposition indeholdende excitalopram
PE20040991A1 (es) 2002-08-12 2004-12-27 Lundbeck & Co As H Separacion de intermediarios para la preparacion de escitalopram
TR200504022T1 (tr) * 2003-03-24 2006-08-21 Hetero Drugs Limited (S)-sitalopram oksalatın yeni sıvı kristal formları.
US20040265375A1 (en) * 2003-04-16 2004-12-30 Platteeuw Johannes J. Orally disintegrating tablets
TWI339651B (en) * 2004-02-12 2011-04-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
US20050196453A1 (en) 2004-03-05 2005-09-08 H. Lundbeck A/S Crystalline composition containing escitalopram
NZ549100A (en) * 2004-03-05 2010-02-26 Lundbeck & Co As H Crystalline composition containing escitalopram oxalate
WO2006123243A2 (en) * 2005-05-20 2006-11-23 Aurobindo Pharma Limited Pharmaceutical dosage forms comprising escitalopram in form of granules
TWI358407B (en) * 2005-06-22 2012-02-21 Lundbeck & Co As H Crystalline base of escitalopram and orodispersibl
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
ES2308750T3 (es) * 2005-08-29 2008-12-01 Teva Pharmaceutical Industries Ltd Tadalafil en particulas solidas que presenta una distribucion de particulas bimodal.
US7569605B2 (en) 2005-10-14 2009-08-04 Forest Laboratories Holdings Limited Methods of treating central nervous system disorders with a low dose combination of escitalopram and bupropion
US20070134322A1 (en) * 2005-12-14 2007-06-14 Forest Laboratories, Inc. Modified and pulsatile release pharmaceutical formulations of escitalopram
GB0601286D0 (en) 2006-01-23 2006-03-01 Sandoz Ag Asymmetric synthesis
WO2008059514A2 (en) * 2006-07-31 2008-05-22 Cadila Healthcare Limited Process for preparing escitalopram
EP2086509A1 (en) 2006-10-20 2009-08-12 Ratiopharm GmbH Escitalopram and solid pharmaceutical composition comprising the same
US20090048336A1 (en) * 2007-08-17 2009-02-19 Naveen Kumar Kolla Escitalopram oxalate powders
WO2009135646A2 (en) * 2008-05-05 2009-11-12 Farmaprojects, Sa Stable pharmaceutical compositions and their processes for preparation suitable for industrial scale
EP2116231A1 (en) 2008-05-07 2009-11-11 Hexal Ag Granulate comprising escitalopram oxalate
GR20080100696A (el) 2008-10-23 2010-05-13 Genepharm �.�. Φαρμακοτεχνικη μορφη με βελτιωμενη γευση του φαρμακευτικα αποδεκτου αλατος εσιταλοπραμης
ITMI20120448A1 (it) * 2012-01-30 2013-07-31 Carthesia Sas Composizione liofilizzata di escitalopram ossalato per somministrazione sublinguale
ITMI20120106A1 (it) * 2012-01-30 2013-07-31 Carthesia S A S Pastiglie liofilizzate di escitalopram ossalato per somministrazione sublinguale
WO2017020841A1 (zh) * 2015-08-03 2017-02-09 深圳信立泰药业股份有限公司 一种含有lcz696的药物组合物及其制备方法
JP2018016569A (ja) * 2016-07-26 2018-02-01 株式会社トクヤマ （１ｓ）−１−［３−（ジメチルアミノ）プロピル］−１−（４−フルオロフェニル）−１，３−ジヒドロイソベンゾフラン−５−カルボニトリル蓚酸塩の製造方法
JP6423133B1 (ja) * 2017-04-10 2018-11-14 東和薬品株式会社 エスシタロプラム医薬組成物
CN107441052A (zh) * 2017-06-21 2017-12-08 山东京卫制药有限公司 一种含有草酸艾司西酞普兰的片剂及其制备方法
KR102089737B1 (ko) * 2017-11-01 2020-03-16 한국화학연구원 에씨탈로프람을 함유한 미립구형 서방출 주사제 및 그의 제조방법
JP7453859B2 (ja) 2020-06-22 2024-03-21 東和薬品株式会社 エスシタロプラム錠剤

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (es) * 1965-03-18
GB1358915A (en) 1971-09-13 1974-07-03 Merck & Co Inc Directly compressed tablet and composition therefor
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
ES2058061T3 (es) * 1985-10-25 1994-11-01 Beecham Group Plc Derivado de piperidina, su preparacion y su uso como medicamento.
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) * 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
GB9325644D0 (en) 1993-12-15 1994-02-16 Smithkline Beecham Plc Novel formulation
US5683720A (en) * 1994-10-28 1997-11-04 Fuisz Technologies Ltd. Liquiflash particles and method of making same
EP0714663A3 (en) 1994-11-28 1997-01-15 Lilly Co Eli Potentiation of drug responses by serotonin 1A receptor antagonists
AU5966196A (en) 1995-06-08 1997-01-09 Eli Lilly And Company Methods of treating cold and allergic rhinitis
ATE205824T1 (de) 1997-07-08 2001-10-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
GB9714841D0 (en) 1997-07-14 1997-09-17 Smithkline Beecham Plc Treatment method
US5980941A (en) * 1997-08-20 1999-11-09 Fuisz Technologies Ltd. Self-binding shearform compositions
US5840334A (en) * 1997-08-20 1998-11-24 Fuisz Technologies Ltd. Self-binding shearform compositions
US5869098A (en) * 1997-08-20 1999-02-09 Fuisz Technologies Ltd. Fast-dissolving comestible units formed under high-speed/high-pressure conditions
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
CA2291072C (en) 1997-11-11 2002-08-20 H. Lundbeck A/S Method for the preparation of citalopram
PL199423B1 (pl) 1998-10-20 2008-09-30 Lundbeck & Co As H Sposób wytwarzania citalopramu
TWI230618B (en) * 1998-12-15 2005-04-11 Gilead Sciences Inc Pharmaceutical compositions of 9-[2-[[bis[(pivaloyloxy)methyl]phosphono]methoxy]ethyl]adenine and tablets or capsules containing the same
BR9917346A (pt) 1999-04-14 2002-02-26 Lundbeck & Co As H Método para preparação de citalopram intermadiário e utilização do mesmo
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
AR021155A1 (es) 1999-07-08 2002-06-12 Lundbeck & Co As H Tratamiento de desordenes neuroticos
JP2003510266A (ja) * 1999-09-28 2003-03-18 ハー・ルンドベック・アクチエゼルスカベット 溶融顆粒化された調合物及びこの調合物から製造された、放出が調節された投薬形
GB2357762B (en) 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US6977306B2 (en) 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof
US20030232881A1 (en) * 2000-10-27 2003-12-18 H. Lundbeck A/S Crystals of pharmaceutically acceptable salts of citalopram, methods of crystallization, and pharmaceutical compositions comprising them
DK1522539T3 (da) * 2001-07-31 2007-05-07 Lundbeck & Co As H Krystallinsk komposition indeholdende excitalopram

Also Published As

Publication number Publication date
CY1106413T1 (el) 2011-10-12
EP1414435A1 (en) 2004-05-06
HK1070000A1 (en) 2005-06-10
IL159326A (en) 2010-05-31
RS8304A (en) 2006-12-15
DE60217932T2 (de) 2007-08-30
NO20040380L (no) 2004-01-28
EP1522539A1 (en) 2005-04-13
JP2012211186A (ja) 2012-11-01
MXPA04000849A (es) 2004-05-14
TNSN04021A1 (en) 2006-06-01
US6916941B2 (en) 2005-07-12
EP1414435B1 (en) 2005-01-12
DE60202615D1 (de) 2005-02-17
EP1522539B1 (en) 2007-01-24
DK1522539T3 (da) 2007-05-07
PT1414435E (pt) 2005-05-31
UY27404A1 (es) 2003-02-28
JP4971477B2 (ja) 2012-07-11
HUP0401946A2 (hu) 2005-01-28
US20080305164A1 (en) 2008-12-11
SI1414435T1 (en) 2005-06-30
HRP20080410A2 (en) 2008-10-31
TR200400189T2 (tr) 2004-12-21
ES2280892T3 (es) 2007-09-16
ZA200309684B (en) 2004-12-22
PL366995A1 (en) 2005-02-07
UA79930C2 (en) 2007-08-10
JP2005525993A (ja) 2005-09-02
CN1660074A (zh) 2005-08-31
EA006213B1 (ru) 2005-10-27
JP2010150283A (ja) 2010-07-08
HRP20031073A2 (en) 2004-04-30
BR0206164A (pt) 2003-10-28
NO328346B1 (no) 2010-02-01
CO5560540A2 (es) 2005-09-30
CN1311819C (zh) 2007-04-25
US7420069B2 (en) 2008-09-02
AU2002355624B2 (en) 2006-02-02
JP5192568B2 (ja) 2013-05-08
DE60217932D1 (de) 2007-03-15
PT1522539E (pt) 2007-03-30
WO2003011278A1 (en) 2003-02-13
US20030212128A1 (en) 2003-11-13
JP5719811B2 (ja) 2015-05-20
PE20030304A1 (es) 2003-03-27
US20050147674A1 (en) 2005-07-07
ATE286730T1 (de) 2005-01-15
CA2451915C (en) 2010-09-21
NZ530157A (en) 2007-06-29
ATE352546T1 (de) 2007-02-15
JP2011195591A (ja) 2011-10-06
MEP2108A (xx) 2010-02-10
ES2233842T3 (es) 2005-06-16
KR20040028947A (ko) 2004-04-03
DK1414435T3 (da) 2005-05-09
MA27349A1 (fr) 2005-06-01
IS7077A (is) 2003-12-15
HRPK20080410B3 (en) 2009-09-30
IL159326A0 (en) 2004-06-01
MY126238A (en) 2006-09-29
CA2451915A1 (en) 2003-02-13
BG108571A (en) 2005-02-28
CN1536997A (zh) 2004-10-13
EG24206A (en) 2008-10-21
EA200400243A1 (ru) 2004-06-24
DE60202615T2 (de) 2006-01-12

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