MXPA04000849A - Composicion cristalina que contiene escitalopram. - Google Patents
Composicion cristalina que contiene escitalopram.Info
- Publication number
- MXPA04000849A MXPA04000849A MXPA04000849A MXPA04000849A MXPA04000849A MX PA04000849 A MXPA04000849 A MX PA04000849A MX PA04000849 A MXPA04000849 A MX PA04000849A MX PA04000849 A MXPA04000849 A MX PA04000849A MX PA04000849 A MXPA04000849 A MX PA04000849A
- Authority
- MX
- Mexico
- Prior art keywords
- composition containing
- crystalline composition
- containing escitalopram
- escitalopram
- crystalline particles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Se revelan particulas cristalinas de oxalato de escitalopram cuyas particulas tienen un tamano de por lo menos 40 æm. Tambien se revela un metodo para la manufactura de dichas particulas cristalinas y composiciones farmaceuticas que contienen dichas particulas cristalinas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200101164 | 2001-07-31 | ||
PCT/DK2002/000513 WO2003011278A1 (en) | 2001-07-31 | 2002-07-25 | Crystalline composition containing escitalopram |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA04000849A true MXPA04000849A (es) | 2004-05-14 |
Family
ID=8160647
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA04000849A MXPA04000849A (es) | 2001-07-31 | 2002-07-25 | Composicion cristalina que contiene escitalopram. |
Country Status (40)
Country | Link |
---|---|
US (3) | US6916941B2 (es) |
EP (2) | EP1414435B1 (es) |
JP (4) | JP2005525993A (es) |
KR (1) | KR20040028947A (es) |
CN (2) | CN1311819C (es) |
AR (1) | AR034898A1 (es) |
AT (2) | ATE352546T1 (es) |
AU (1) | AU2002355624B2 (es) |
BG (1) | BG108571A (es) |
BR (1) | BR0206164A (es) |
CA (1) | CA2451915C (es) |
CO (1) | CO5560540A2 (es) |
CY (1) | CY1106413T1 (es) |
DE (2) | DE60217932T2 (es) |
DK (2) | DK1522539T3 (es) |
EA (1) | EA006213B1 (es) |
EG (1) | EG24206A (es) |
ES (2) | ES2280892T3 (es) |
HK (1) | HK1070000A1 (es) |
HR (2) | HRP20031073A2 (es) |
HU (1) | HUP0401946A2 (es) |
IL (2) | IL159326A0 (es) |
IS (1) | IS7077A (es) |
MA (1) | MA27349A1 (es) |
ME (1) | MEP2108A (es) |
MX (1) | MXPA04000849A (es) |
MY (1) | MY126238A (es) |
NO (1) | NO328346B1 (es) |
NZ (1) | NZ530157A (es) |
PE (1) | PE20030304A1 (es) |
PL (1) | PL366995A1 (es) |
PT (2) | PT1522539E (es) |
RS (1) | RS8304A (es) |
SI (1) | SI1414435T1 (es) |
TN (1) | TNSN04021A1 (es) |
TR (1) | TR200400189T2 (es) |
UA (1) | UA79930C2 (es) |
UY (1) | UY27404A1 (es) |
WO (1) | WO2003011278A1 (es) |
ZA (1) | ZA200309684B (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2195554T5 (es) | 1999-04-14 | 2010-02-02 | H. Lundbeck A/S | Metodo para la preparacion de citalopram. |
US20030109577A1 (en) * | 2000-10-27 | 2003-06-12 | Ken Liljegren | Pharmaceutical composition containing citalopram |
US20030232881A1 (en) * | 2000-10-27 | 2003-12-18 | H. Lundbeck A/S | Crystals of pharmaceutically acceptable salts of citalopram, methods of crystallization, and pharmaceutical compositions comprising them |
DK1522539T3 (da) | 2001-07-31 | 2007-05-07 | Lundbeck & Co As H | Krystallinsk komposition indeholdende excitalopram |
PE20040991A1 (es) | 2002-08-12 | 2004-12-27 | Lundbeck & Co As H | Separacion de intermediarios para la preparacion de escitalopram |
TR200504022T1 (tr) * | 2003-03-24 | 2006-08-21 | Hetero Drugs Limited | (S)-sitalopram oksalatın yeni sıvı kristal formları. |
US20040265375A1 (en) * | 2003-04-16 | 2004-12-30 | Platteeuw Johannes J. | Orally disintegrating tablets |
TWI339651B (en) * | 2004-02-12 | 2011-04-01 | Lundbeck & Co As H | Method for the separation of intermediates which may be used for the preparation of escitalopram |
US20050196453A1 (en) | 2004-03-05 | 2005-09-08 | H. Lundbeck A/S | Crystalline composition containing escitalopram |
CA2558198A1 (en) * | 2004-03-05 | 2005-09-15 | H. Lundbeck A/S | Crystalline composition containing escitalopram oxalate |
EP1901714A2 (en) * | 2005-05-20 | 2008-03-26 | Aurobindo Pharma Limited | Pharmaceutical dosage forms comprising escitalopram in form of granules |
US7834201B2 (en) | 2005-06-22 | 2010-11-16 | H. Lundbeck A/S | Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base |
TWI347942B (en) * | 2005-06-22 | 2011-09-01 | Lundbeck & Co As H | Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base |
WO2007027612A2 (en) * | 2005-08-29 | 2007-03-08 | Teva Pharmaceutical Industries Ltd. | Solid particulate tadalafil having a bimodal particle size distribution |
WO2007053796A2 (en) | 2005-10-14 | 2007-05-10 | Forest Laboratories, Inc. | Methods of treating central nervous system disorders with a low dose combination of escitalopram and bupropion |
US20070134322A1 (en) * | 2005-12-14 | 2007-06-14 | Forest Laboratories, Inc. | Modified and pulsatile release pharmaceutical formulations of escitalopram |
GB0601286D0 (en) | 2006-01-23 | 2006-03-01 | Sandoz Ag | Asymmetric synthesis |
WO2008059514A2 (en) * | 2006-07-31 | 2008-05-22 | Cadila Healthcare Limited | Process for preparing escitalopram |
EP2086509A1 (en) * | 2006-10-20 | 2009-08-12 | Ratiopharm GmbH | Escitalopram and solid pharmaceutical composition comprising the same |
US20090048336A1 (en) * | 2007-08-17 | 2009-02-19 | Naveen Kumar Kolla | Escitalopram oxalate powders |
WO2009135646A2 (en) * | 2008-05-05 | 2009-11-12 | Farmaprojects, Sa | Stable pharmaceutical compositions and their processes for preparation suitable for industrial scale |
EP2116231A1 (en) | 2008-05-07 | 2009-11-11 | Hexal Ag | Granulate comprising escitalopram oxalate |
GR20080100696A (el) | 2008-10-23 | 2010-05-13 | Genepharm �.�. | Φαρμακοτεχνικη μορφη με βελτιωμενη γευση του φαρμακευτικα αποδεκτου αλατος εσιταλοπραμης |
ITMI20120448A1 (it) * | 2012-01-30 | 2013-07-31 | Carthesia Sas | Composizione liofilizzata di escitalopram ossalato per somministrazione sublinguale |
ITMI20120106A1 (it) * | 2012-01-30 | 2013-07-31 | Carthesia S A S | Pastiglie liofilizzate di escitalopram ossalato per somministrazione sublinguale |
CN106389374A (zh) * | 2015-08-03 | 2017-02-15 | 深圳信立泰药业股份有限公司 | 一种含有lcz696的药物组合物及其制备方法 |
JP2018016569A (ja) * | 2016-07-26 | 2018-02-01 | 株式会社トクヤマ | (1s)−1−[3−(ジメチルアミノ)プロピル]−1−(4−フルオロフェニル)−1,3−ジヒドロイソベンゾフラン−5−カルボニトリル蓚酸塩の製造方法 |
JP6423133B1 (ja) * | 2017-04-10 | 2018-11-14 | 東和薬品株式会社 | エスシタロプラム医薬組成物 |
CN107441052A (zh) * | 2017-06-21 | 2017-12-08 | 山东京卫制药有限公司 | 一种含有草酸艾司西酞普兰的片剂及其制备方法 |
KR102089737B1 (ko) * | 2017-11-01 | 2020-03-16 | 한국화학연구원 | 에씨탈로프람을 함유한 미립구형 서방출 주사제 및 그의 제조방법 |
JP7453859B2 (ja) | 2020-06-22 | 2024-03-21 | 東和薬品株式会社 | エスシタロプラム錠剤 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1143702A (es) | 1965-03-18 | |||
GB1358915A (en) | 1971-09-13 | 1974-07-03 | Merck & Co Inc | Directly compressed tablet and composition therefor |
GB1526331A (en) * | 1976-01-14 | 1978-09-27 | Kefalas As | Phthalanes |
GB8419963D0 (en) | 1984-08-06 | 1984-09-12 | Lundbeck & Co As H | Intermediate compound and method |
EP0223403B1 (en) | 1985-10-25 | 1993-08-04 | Beecham Group Plc | Piperidine derivative, its preparation, and its use as medicament |
GB8814057D0 (en) | 1988-06-14 | 1988-07-20 | Lundbeck & Co As H | New enantiomers & their isolation |
US5296507A (en) | 1990-09-06 | 1994-03-22 | H.Lundbeck A/S | Treatment of cerbrovascular disorders |
GB9325644D0 (en) | 1993-12-15 | 1994-02-16 | Smithkline Beecham Plc | Novel formulation |
US5683720A (en) | 1994-10-28 | 1997-11-04 | Fuisz Technologies Ltd. | Liquiflash particles and method of making same |
EP0714663A3 (en) | 1994-11-28 | 1997-01-15 | Lilly Co Eli | Potentiation of drug responses by serotonin 1A receptor antagonists |
AU5966196A (en) | 1995-06-08 | 1997-01-09 | Eli Lilly And Company | Methods of treating cold and allergic rhinitis |
PT1015416E (pt) | 1997-07-08 | 2002-03-28 | Lundbeck & Co As H | Metodo para a producao de citalopram |
GB9714841D0 (en) | 1997-07-14 | 1997-09-17 | Smithkline Beecham Plc | Treatment method |
US5980941A (en) | 1997-08-20 | 1999-11-09 | Fuisz Technologies Ltd. | Self-binding shearform compositions |
US5840334A (en) | 1997-08-20 | 1998-11-24 | Fuisz Technologies Ltd. | Self-binding shearform compositions |
US5869098A (en) | 1997-08-20 | 1999-02-09 | Fuisz Technologies Ltd. | Fast-dissolving comestible units formed under high-speed/high-pressure conditions |
UA62985C2 (en) | 1997-11-10 | 2004-01-15 | Lunnbeck As H | A method for the preparation of citalopram |
JP3813820B2 (ja) | 1997-11-11 | 2006-08-23 | ハー・ルンドベック・アクチエゼルスカベット | シタロプラムの製造方法 |
EP1123284B1 (en) | 1998-10-20 | 2003-01-08 | H. Lundbeck A/S | Method for the preparation of citalopram |
TWI230618B (en) * | 1998-12-15 | 2005-04-11 | Gilead Sciences Inc | Pharmaceutical compositions of 9-[2-[[bis[(pivaloyloxy)methyl]phosphono]methoxy]ethyl]adenine and tablets or capsules containing the same |
ES2195554T5 (es) | 1999-04-14 | 2010-02-02 | H. Lundbeck A/S | Metodo para la preparacion de citalopram. |
ITMI991579A1 (it) | 1999-06-25 | 2001-01-15 | Lundbeck & Co As H | Metodo per la preparazione di citalopram |
AR021155A1 (es) | 1999-07-08 | 2002-06-12 | Lundbeck & Co As H | Tratamiento de desordenes neuroticos |
JP2003510266A (ja) * | 1999-09-28 | 2003-03-18 | ハー・ルンドベック・アクチエゼルスカベット | 溶融顆粒化された調合物及びこの調合物から製造された、放出が調節された投薬形 |
GB2357762B (en) | 2000-03-13 | 2002-01-30 | Lundbeck & Co As H | Crystalline base of citalopram |
US6977306B2 (en) | 2000-05-02 | 2005-12-20 | Sumitomo Chemical Company, Limited | Citalopram hydrobromide crystal and method for crystallization thereof |
US20030232881A1 (en) * | 2000-10-27 | 2003-12-18 | H. Lundbeck A/S | Crystals of pharmaceutically acceptable salts of citalopram, methods of crystallization, and pharmaceutical compositions comprising them |
DK1522539T3 (da) | 2001-07-31 | 2007-05-07 | Lundbeck & Co As H | Krystallinsk komposition indeholdende excitalopram |
-
2002
- 2002-07-25 DK DK04029282T patent/DK1522539T3/da active
- 2002-07-25 PT PT04029282T patent/PT1522539E/pt unknown
- 2002-07-25 SI SI200230091T patent/SI1414435T1/xx unknown
- 2002-07-25 EA EA200400243A patent/EA006213B1/ru not_active IP Right Cessation
- 2002-07-25 AR ARP020102808A patent/AR034898A1/es unknown
- 2002-07-25 EP EP02750846A patent/EP1414435B1/en not_active Revoked
- 2002-07-25 ES ES04029282T patent/ES2280892T3/es not_active Expired - Lifetime
- 2002-07-25 MX MXPA04000849A patent/MXPA04000849A/es active IP Right Grant
- 2002-07-25 DK DK02750846T patent/DK1414435T3/da active
- 2002-07-25 CN CNB028150317A patent/CN1311819C/zh not_active Expired - Lifetime
- 2002-07-25 CN CN2004100941660A patent/CN1660074A/zh active Pending
- 2002-07-25 WO PCT/DK2002/000513 patent/WO2003011278A1/en active Application Filing
- 2002-07-25 AU AU2002355624A patent/AU2002355624B2/en not_active Ceased
- 2002-07-25 IL IL15932602A patent/IL159326A0/xx unknown
- 2002-07-25 AT AT04029282T patent/ATE352546T1/de not_active IP Right Cessation
- 2002-07-25 TR TR2004/00189T patent/TR200400189T2/xx unknown
- 2002-07-25 EP EP04029282A patent/EP1522539B1/en not_active Revoked
- 2002-07-25 DE DE60217932T patent/DE60217932T2/de not_active Revoked
- 2002-07-25 KR KR10-2004-7001140A patent/KR20040028947A/ko not_active Application Discontinuation
- 2002-07-25 ME MEP-21/08A patent/MEP2108A/xx unknown
- 2002-07-25 HU HU0401946A patent/HUP0401946A2/hu unknown
- 2002-07-25 ES ES02750846T patent/ES2233842T3/es not_active Expired - Lifetime
- 2002-07-25 CA CA2451915A patent/CA2451915C/en not_active Expired - Fee Related
- 2002-07-25 JP JP2003516508A patent/JP2005525993A/ja active Pending
- 2002-07-25 UA UA20031212659A patent/UA79930C2/uk unknown
- 2002-07-25 NZ NZ530157A patent/NZ530157A/en not_active IP Right Cessation
- 2002-07-25 ZA ZA200309684A patent/ZA200309684B/xx unknown
- 2002-07-25 AT AT02750846T patent/ATE286730T1/de active
- 2002-07-25 RS YU8304A patent/RS8304A/sr unknown
- 2002-07-25 PT PT02750846T patent/PT1414435E/pt unknown
- 2002-07-25 PL PL02366995A patent/PL366995A1/xx unknown
- 2002-07-25 DE DE60202615T patent/DE60202615T2/de not_active Revoked
- 2002-07-25 BR BR0206164-3A patent/BR0206164A/pt not_active Application Discontinuation
- 2002-07-26 PE PE2002000675A patent/PE20030304A1/es not_active Application Discontinuation
- 2002-07-28 EG EG2002070849A patent/EG24206A/xx active
- 2002-07-30 MY MYPI20022871A patent/MY126238A/en unknown
- 2002-07-30 UY UY27404A patent/UY27404A1/es not_active Application Discontinuation
-
2003
- 2003-03-31 US US10/403,453 patent/US6916941B2/en not_active Expired - Lifetime
- 2003-12-11 IL IL159326A patent/IL159326A/en unknown
- 2003-12-15 IS IS7077A patent/IS7077A/is unknown
- 2003-12-23 HR HR20031073A patent/HRP20031073A2/xx not_active Application Discontinuation
-
2004
- 2004-01-27 TN TNP2004000021A patent/TNSN04021A1/en unknown
- 2004-01-28 NO NO20040380A patent/NO328346B1/no not_active IP Right Cessation
- 2004-02-04 MA MA27512A patent/MA27349A1/fr unknown
- 2004-02-09 BG BG108571A patent/BG108571A/xx unknown
- 2004-02-25 CO CO04016758A patent/CO5560540A2/es not_active Application Discontinuation
-
2005
- 2005-02-07 US US11/053,641 patent/US7420069B2/en not_active Expired - Lifetime
- 2005-04-04 HK HK05102804A patent/HK1070000A1/xx not_active IP Right Cessation
-
2007
- 2007-03-23 CY CY20071100411T patent/CY1106413T1/el unknown
-
2008
- 2008-08-22 HR HR20080410A patent/HRPK20080410B3/xx not_active IP Right Cessation
- 2008-08-22 US US12/196,812 patent/US20080305164A1/en not_active Abandoned
-
2010
- 2010-03-16 JP JP2010059368A patent/JP4971477B2/ja not_active Expired - Lifetime
-
2011
- 2011-05-30 JP JP2011120483A patent/JP5192568B2/ja not_active Expired - Lifetime
-
2012
- 2012-07-26 JP JP2012166170A patent/JP5719811B2/ja not_active Expired - Lifetime
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Legal Events
Date | Code | Title | Description |
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FG | Grant or registration |