IL105264A - Pyrimidine derivatives processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents

Pyrimidine derivatives processes for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number
IL105264A
IL105264A IL10526493A IL10526493A IL105264A IL 105264 A IL105264 A IL 105264A IL 10526493 A IL10526493 A IL 10526493A IL 10526493 A IL10526493 A IL 10526493A IL 105264 A IL105264 A IL 105264A
Authority
IL
Israel
Prior art keywords
phenyl
lower alkyl
pyridyl
formula
compound
Prior art date
Application number
IL10526493A
Other languages
English (en)
Other versions
IL105264A0 (en
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4202064&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL105264(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL105264A0 publication Critical patent/IL105264A0/xx
Publication of IL105264A publication Critical patent/IL105264A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Paints Or Removers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL10526493A 1992-04-03 1993-04-01 Pyrimidine derivatives processes for the preparation thereof and pharmaceutical compositions containing them IL105264A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH108392 1992-04-03

Publications (2)

Publication Number Publication Date
IL105264A0 IL105264A0 (en) 1993-08-18
IL105264A true IL105264A (en) 1999-04-11

Family

ID=4202064

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10526493A IL105264A (en) 1992-04-03 1993-04-01 Pyrimidine derivatives processes for the preparation thereof and pharmaceutical compositions containing them

Country Status (29)

Country Link
EP (1) EP0564409B1 (en:Method)
JP (1) JP2706682B2 (en:Method)
KR (1) KR100261366B1 (en:Method)
CN (1) CN1043531C (en:Method)
AT (1) ATE188964T1 (en:Method)
AU (1) AU666709B2 (en:Method)
BR (1) BR1100739A (en:Method)
CA (1) CA2093203C (en:Method)
CY (2) CY2229B1 (en:Method)
CZ (1) CZ283944B6 (en:Method)
DE (2) DE10299016I2 (en:Method)
DK (1) DK0564409T3 (en:Method)
ES (1) ES2142857T3 (en:Method)
FI (1) FI109534B (en:Method)
GR (1) GR3032927T3 (en:Method)
HU (2) HU226488B1 (en:Method)
IL (1) IL105264A (en:Method)
LU (1) LU90908I2 (en:Method)
MX (1) MX9301929A (en:Method)
NL (1) NL300086I2 (en:Method)
NO (2) NO302473B1 (en:Method)
NZ (1) NZ247299A (en:Method)
PT (1) PT564409E (en:Method)
RU (1) RU2125992C1 (en:Method)
SA (1) SA93140441B1 (en:Method)
SG (1) SG43859A1 (en:Method)
SK (1) SK280620B6 (en:Method)
TW (1) TW225528B (en:Method)
ZA (1) ZA932397B (en:Method)

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* Cited by examiner, † Cited by third party
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