ID21649A - Inhibitor serum protease, terutama virus hepatitis c ns3 protease - Google Patents

Inhibitor serum protease, terutama virus hepatitis c ns3 protease

Info

Publication number
ID21649A
ID21649A IDW990198A ID990198A ID21649A ID 21649 A ID21649 A ID 21649A ID W990198 A IDW990198 A ID W990198A ID 990198 A ID990198 A ID 990198A ID 21649 A ID21649 A ID 21649A
Authority
ID
Indonesia
Prior art keywords
protease
virus hepatitis
especially virus
inhibitor serum
inhibitor
Prior art date
Application number
IDW990198A
Other languages
English (en)
Inventor
Roger D Tung
Scott L Harbeson
David D Deininger
Mark A Murcko
Govinda Rao Bhisetti
Luc J Farmer
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of ID21649A publication Critical patent/ID21649A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
IDW990198A 1996-10-18 1997-10-17 Inhibitor serum protease, terutama virus hepatitis c ns3 protease ID21649A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2829096P 1996-10-18 1996-10-18

Publications (1)

Publication Number Publication Date
ID21649A true ID21649A (id) 1999-07-08

Family

ID=21842625

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW990198A ID21649A (id) 1996-10-18 1997-10-17 Inhibitor serum protease, terutama virus hepatitis c ns3 protease

Country Status (34)

Country Link
US (5) US6265380B1 (id)
EP (3) EP0932617B1 (id)
JP (3) JP4080541B2 (id)
KR (1) KR100509388B1 (id)
CN (1) CN1133649C (id)
AP (1) AP1019A (id)
AT (1) ATE212037T1 (id)
BG (1) BG103392A (id)
BR (1) BR9712544B1 (id)
CA (1) CA2268391A1 (id)
CZ (1) CZ298749B6 (id)
DE (1) DE69709671T2 (id)
DK (1) DK0932617T3 (id)
EA (1) EA001915B1 (id)
EE (1) EE04023B1 (id)
ES (1) ES2169880T3 (id)
GE (1) GEP20012471B (id)
HK (1) HK1023779A1 (id)
HU (1) HU227742B1 (id)
ID (1) ID21649A (id)
IL (3) IL129407A0 (id)
IN (1) IN183120B (id)
IS (1) IS5028A (id)
MX (1) MXPA05003026A (id)
NO (2) NO329751B1 (id)
NZ (1) NZ335276A (id)
PL (2) PL192280B1 (id)
PT (1) PT932617E (id)
SK (1) SK286105B6 (id)
TR (1) TR199901602T2 (id)
TW (1) TW530065B (id)
UA (2) UA79749C2 (id)
WO (1) WO1998017679A1 (id)
ZA (1) ZA979327B (id)

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