PL194025B1
(pl)
*
|
1996-10-18 |
2007-04-30 |
Vertex Pharma |
Inhibitory proteaz serynowych, a zwłaszcza proteazy wirusa NS3 zapalenia wątroby C, kompozycja farmaceutyczna i zastosowanie inhibitorów proteaz serynowych
|
GB9707659D0
(en)
*
|
1997-04-16 |
1997-06-04 |
Peptide Therapeutics Ltd |
Hepatitis C NS3 Protease inhibitors
|
ES2234144T3
(es)
*
|
1997-08-11 |
2005-06-16 |
Boehringer Ingelheim (Canada) Ltd. |
Analogos de peptidos inhibidores de la hepatitis c.
|
ATE291032T1
(de)
*
|
1997-08-11 |
2005-04-15 |
Boehringer Ingelheim Ca Ltd |
Hepatitis c inhibitor peptide
|
US6767991B1
(en)
|
1997-08-11 |
2004-07-27 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis C inhibitor peptides
|
GB9806815D0
(en)
*
|
1998-03-30 |
1998-05-27 |
Hoffmann La Roche |
Amino acid derivatives
|
JP4690545B2
(ja)
*
|
1998-03-31 |
2011-06-01 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
セリンプロテアーゼ、特にc型肝炎ウイルスns3プロテアーゼの阻害因子
|
GB9809664D0
(en)
*
|
1998-05-06 |
1998-07-01 |
Hoffmann La Roche |
a-Ketoamide derivatives
|
GB9812523D0
(en)
*
|
1998-06-10 |
1998-08-05 |
Angeletti P Ist Richerche Bio |
Peptide inhibitors of hepatitis c virus ns3 protease
|
AR022061A1
(es)
*
|
1998-08-10 |
2002-09-04 |
Boehringer Ingelheim Ca Ltd |
Peptidos inhibidores de la hepatitis c, una composicion farmaceutica que los contiene, el uso de los mismos para preparar una composicion farmaceutica, el uso de un producto intermedio para la preparacion de estos peptidos y un procedimiento para la preparacion de un peptido analogo de los mismos.
|
US6323180B1
(en)
|
1998-08-10 |
2001-11-27 |
Boehringer Ingelheim (Canada) Ltd |
Hepatitis C inhibitor tri-peptides
|
CA2360740A1
(en)
|
1999-03-02 |
2000-09-08 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Compounds useful as reversible inhibitors of cathepsin s
|
US6608027B1
(en)
|
1999-04-06 |
2003-08-19 |
Boehringer Ingelheim (Canada) Ltd |
Macrocyclic peptides active against the hepatitis C virus
|
UA74546C2
(en)
*
|
1999-04-06 |
2006-01-16 |
Boehringer Ingelheim Ca Ltd |
Macrocyclic peptides having activity relative to hepatitis c virus, a pharmaceutical composition and use of the pharmaceutical composition
|
AU5788800A
(en)
*
|
1999-07-07 |
2001-01-22 |
Du Pont Pharmaceuticals Company |
Peptide boronic acid inhibitors of hepatitis c virus protease
|
CA2376961A1
(en)
*
|
1999-07-26 |
2001-02-01 |
Bristol-Myers Squibb Pharma Company |
Lactam inhibitors of hepatitis c virus ns3 protease
|
US7122627B2
(en)
|
1999-07-26 |
2006-10-17 |
Bristol-Myers Squibb Company |
Lactam inhibitors of Hepatitis C virus NS3 protease
|
US6420364B1
(en)
|
1999-09-13 |
2002-07-16 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Compound useful as reversible inhibitors of cysteine proteases
|
US7026469B2
(en)
|
2000-10-19 |
2006-04-11 |
Wake Forest University School Of Medicine |
Compositions and methods of double-targeting virus infections and cancer cells
|
WO2001040262A1
(en)
*
|
1999-12-03 |
2001-06-07 |
Bristol-Myers Squibb Pharma Company |
Alpha-ketoamide inhibitors of hepatitis c virus ns3 protease
|
DE60021282T2
(de)
*
|
1999-12-07 |
2006-05-18 |
Theravance, Inc., South San Francisco |
Carbamat-derivate als muscarin-rezeptor antonisten
|
AU2001245356A1
(en)
*
|
2000-02-29 |
2001-09-12 |
Bristol-Myers Squibb Pharma Company |
Inhibitors of hepatitis c virus ns3 protease
|
ES2240446T3
(es)
|
2000-04-03 |
2005-10-16 |
Vertex Pharma |
Inhibidores de serina proteasas, particularmente la proteasa ns3 del virus de la hepatitis c.
|
AU2006202124B2
(en)
*
|
2000-04-03 |
2010-01-21 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of Serine Proteases, Particularly Hepatitis C Virus NS3 Protease
|
DE60137207D1
(de)
|
2000-04-05 |
2009-02-12 |
Schering Corp |
Makrozyklische inhibitoren der ns3-serinprotease des hepatitis c-virus mit stickstoffhaltigen zyklischen p2-gruppen
|
SK14952002A3
(sk)
|
2000-04-19 |
2003-03-04 |
Schering Corporation |
Makrocyklické zlúčeniny, farmaceutický prostriedok s ich obsahom a ich použitie
|
PE20011350A1
(es)
|
2000-05-19 |
2002-01-15 |
Vertex Pharma |
PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
|
MY164523A
(en)
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
NZ547204A
(en)
|
2000-05-26 |
2008-01-31 |
Idenix Cayman Ltd |
Methods and compositions for treating flaviviruses and pestiviruses
|
US20020007324A1
(en)
*
|
2000-06-09 |
2002-01-17 |
Centner David J. |
System and method for effectively conducting transactions between buyers and suppliers
|
PL206255B1
(pl)
*
|
2000-07-21 |
2010-07-30 |
Dendreon Corporationdendreon Corporation |
Inhibitor proteazy wirusa zapalenia wątroby C, zawierająca go kompozycja farmaceutyczna i zastosowanie inhibitora do wytwarzania leku do leczenia chorób związanych z HCV oraz zastosowanie do wytwarzania kompozycji do stosowania w kombinowanej terapii
|
BR0112666A
(pt)
*
|
2000-07-21 |
2003-06-10 |
Schering Corp |
Peptìdeos como inibidores de ns3-serina protease de vìrus da hepatite c
|
AR034127A1
(es)
|
2000-07-21 |
2004-02-04 |
Schering Corp |
Imidazolidinonas como inhibidores de ns3-serina proteasa del virus de hepatitis c, composicion farmaceutica, un metodo para su preparacion, y el uso de las mismas para la manufactura de un medicamento
|
US7244721B2
(en)
*
|
2000-07-21 |
2007-07-17 |
Schering Corporation |
Peptides as NS3-serine protease inhibitors of hepatitis C virus
|
AR029851A1
(es)
|
2000-07-21 |
2003-07-16 |
Dendreon Corp |
Nuevos peptidos como inhibidores de ns3-serina proteasa del virus de hepatitis c
|
SV2003000617A
(es)
*
|
2000-08-31 |
2003-01-13 |
Lilly Co Eli |
Inhibidores de la proteasa peptidomimetica ref. x-14912m
|
US20040106539A1
(en)
*
|
2000-10-12 |
2004-06-03 |
Ulrich Schubert |
Agents for the treatment of viral infections
|
PT1411954E
(pt)
|
2000-10-18 |
2011-03-16 |
Pharmasset Inc |
Nucleosídeos modificados para o tratamento de infecções virais e proliferação celular anormal
|
US6846806B2
(en)
|
2000-10-23 |
2005-01-25 |
Bristol-Myers Squibb Company |
Peptide inhibitors of Hepatitis C virus NS3 protein
|
US6911428B2
(en)
*
|
2000-12-12 |
2005-06-28 |
Schering Corporation |
Diaryl peptides as NS3-serine protease inhibitors of hepatitis C virus
|
US6653295B2
(en)
|
2000-12-13 |
2003-11-25 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus NS3 protease
|
AU2002230764A1
(en)
*
|
2000-12-13 |
2002-06-24 |
Bristol-Myers Squibb Pharma Company |
Imidazolidinones and their related derivatives as hepatitis c virus ns3 protease inhibitors
|
MY134070A
(en)
|
2001-01-22 |
2007-11-30 |
Isis Pharmaceuticals Inc |
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
|
CN100402549C
(zh)
|
2001-07-11 |
2008-07-16 |
沃泰克斯药物股份有限公司 |
桥连二环的丝氨酸蛋白酶抑制剂
|
US7241796B2
(en)
|
2001-10-24 |
2007-07-10 |
Vertex Pharmaceuticals Inc. |
Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
|
MY151199A
(en)
*
|
2001-11-02 |
2014-04-30 |
Rigel Pharmaceuticals Inc |
Substituted diphenyl heterocycles useful for treating hcv infection
|
CA2473070C
(en)
|
2002-01-23 |
2009-10-13 |
Schering Corporation |
Proline compounds as ns3-serine protease inhibitors for use in treatment of hepatites c virus infection
|
US7119072B2
(en)
|
2002-01-30 |
2006-10-10 |
Boehringer Ingelheim (Canada) Ltd. |
Macrocyclic peptides active against the hepatitis C virus
|
US6642204B2
(en)
|
2002-02-01 |
2003-11-04 |
Boehringer Ingelheim International Gmbh |
Hepatitis C inhibitor tri-peptides
|
US7091184B2
(en)
|
2002-02-01 |
2006-08-15 |
Boehringer Ingelheim International Gmbh |
Hepatitis C inhibitor tri-peptides
|
NZ561851A
(en)
*
|
2002-04-11 |
2009-05-31 |
Vertex Pharma |
Inhibitors of serine proteases, particularly hepatitis C virus NS3 - NS4 protease
|
MY140680A
(en)
|
2002-05-20 |
2010-01-15 |
Bristol Myers Squibb Co |
Hepatitis c virus inhibitors
|
EP1506000B9
(de)
|
2002-05-20 |
2011-08-31 |
Bristol-Myers Squibb Company |
Heterocyclische sulfonamid-hepatitis-c-virus-hemmer
|
AU2003299519A1
(en)
*
|
2002-05-20 |
2004-05-04 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
WO2004043339A2
(en)
|
2002-05-20 |
2004-05-27 |
Bristol-Myers Squibb Company |
Substituted cycloalkyl p1' hepatitis c virus inhibitors
|
EP2799442A1
(de)
|
2002-06-28 |
2014-11-05 |
IDENIX Pharmaceuticals, Inc. |
Modifizierte 2'- und 3'-Nukleosid-Prodrugs zur Behandlung von Flaviridae-Infektionen
|
AU2003277891A1
(en)
*
|
2002-09-23 |
2004-04-08 |
Medivir Ab |
Hcv ns-3 serine protease inhibitors
|
US20050075279A1
(en)
|
2002-10-25 |
2005-04-07 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
HUE033832T2
(en)
|
2002-11-15 |
2018-01-29 |
Idenix Pharmaceuticals Llc |
2'-methyl nucleosides in combination with interferon and Flaviviridae mutation
|
TW200510391A
(en)
|
2003-04-11 |
2005-03-16 |
Vertex Pharma |
Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
|
AU2011203054B2
(en)
*
|
2003-04-11 |
2012-04-26 |
Vertex Pharmaceuticals, Incorporated |
Inhibitors of Serine Proteases, Particularly HCV NS3-NS4A Protease
|
EP2332935A1
(de)
*
|
2003-04-11 |
2011-06-15 |
Vertex Pharmaceuticals Incorporated |
Inhibitoren von Serinproteasen, insbesondere HCV-NS3-NS4A-Protease
|
WO2004099165A2
(en)
|
2003-05-02 |
2004-11-18 |
Rigel Pharmaceuticals, Inc. |
Heterocyclic compounds and hydro isomers thereof
|
MXPA05012545A
(es)
|
2003-05-21 |
2006-02-08 |
Boehringer Ingelheim Int |
Compuestos inhibidores de la hepatitis c.
|
ES2586668T3
(es)
|
2003-05-30 |
2016-10-18 |
Gilead Pharmasset Llc |
Análogos de nucleósidos fluorados modificados
|
CN1852920B
(zh)
|
2003-07-18 |
2010-12-15 |
沃泰克斯药物股份有限公司 |
丝氨酸蛋白酶抑制剂、特别是hcv ns3-ns4a蛋白酶抑制剂
|
AU2004258750A1
(en)
|
2003-07-25 |
2005-02-03 |
Centre National De La Recherche Scientifique -Cnrs |
Purine nucleoside analogues for treating diseases caused by flaviviridae including hepatitis C
|
US7223745B2
(en)
|
2003-08-14 |
2007-05-29 |
Cephalon, Inc. |
Proteasome inhibitors and methods of using the same
|
US7576206B2
(en)
|
2003-08-14 |
2009-08-18 |
Cephalon, Inc. |
Proteasome inhibitors and methods of using the same
|
WO2005021584A2
(en)
|
2003-08-26 |
2005-03-10 |
Schering Corporation |
Novel peptidomimetic ns3-serine protease inhibitors of hepatitis c virus
|
PE20050374A1
(es)
*
|
2003-09-05 |
2005-05-30 |
Vertex Pharma |
Inhibidores de proteasas de serina, en particular proteasa ns3-ns4a del vhc
|
AU2004274468B2
(en)
*
|
2003-09-18 |
2009-07-23 |
Vertex Pharmaceuticals, Incorporated |
Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
|
MXPA06003141A
(es)
|
2003-09-22 |
2006-06-05 |
Boehringer Ingelheim Int |
Peptidos macrociclicos activos contra el virus de la hepatitis c.
|
JP4525982B2
(ja)
|
2003-09-26 |
2010-08-18 |
シェーリング コーポレイション |
C型肝炎ウイルスのns3セリンプロテアーゼの大環状インヒビター
|
KR20120010278A
(ko)
*
|
2003-10-10 |
2012-02-02 |
버텍스 파마슈티칼스 인코포레이티드 |
세린 프로테아제, 특히 hcv ns3-ns4a 프로테아제의 억제제
|
PL1680137T3
(pl)
|
2003-10-14 |
2013-04-30 |
F Hoffmann La Roche Ltd |
Makrocykliczny kwas karboksylowy i związek acylosulfonamidowy jako inhibitor replikacji HCV
|
EP1944042A1
(de)
|
2003-10-27 |
2008-07-16 |
Vertex Pharmceuticals Incorporated |
Kombinationen für die HCV-Behandlung
|
CA2551074A1
(en)
|
2003-10-27 |
2005-05-12 |
Vertex Pharmaceuticals Incorporated |
Hcv ns3-ns4a protease resistance mutants
|
US8187874B2
(en)
|
2003-10-27 |
2012-05-29 |
Vertex Pharmaceuticals Incorporated |
Drug discovery method
|
US7132504B2
(en)
|
2003-11-12 |
2006-11-07 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7135462B2
(en)
|
2003-11-20 |
2006-11-14 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7309708B2
(en)
|
2003-11-20 |
2007-12-18 |
Birstol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
JP2007532479A
(ja)
|
2003-11-20 |
2007-11-15 |
シェーリング コーポレイション |
C型肝炎ウイルスns3プロテアーゼの脱ペプチド化インヒビター
|
GB0500020D0
(en)
|
2005-01-04 |
2005-02-09 |
Novartis Ag |
Organic compounds
|
ES2358333T3
(es)
|
2004-01-21 |
2011-05-09 |
Boehringer Ingelheim International Gmbh |
Péptidos macrocíclicos con acción contra el virus de la hepatitis c.
|
ES2336009T3
(es)
*
|
2004-01-30 |
2010-04-07 |
Medivir Ab |
Inhibidores de la ns-3 serina proteasa del vhc.
|
WO2005077969A2
(en)
*
|
2004-02-04 |
2005-08-25 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
|
ATE428714T1
(de)
|
2004-02-24 |
2009-05-15 |
Japan Tobacco Inc |
Kondensierte heterotetracyclische verbindungen und deren verwendung als hcv-polymerase-inhibitor
|
US20070049593A1
(en)
|
2004-02-24 |
2007-03-01 |
Japan Tobacco Inc. |
Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor
|
KR101316137B1
(ko)
|
2004-02-27 |
2013-10-10 |
머크 샤프 앤드 돔 코포레이션 |
C형 간염 바이러스 ns3 세린 프로테아제의 억제제로서의황 화합물
|
KR20060124725A
(ko)
|
2004-02-27 |
2006-12-05 |
쉐링 코포레이션 |
C형 간염 바이러스 ns3 프로테아제의 억제제
|
CA2557247A1
(en)
|
2004-02-27 |
2005-09-22 |
Schering Corporation |
Compounds as inhibitors of hepatitis c virus ns3 serine protease
|
EP1939213B1
(de)
|
2004-02-27 |
2010-08-25 |
Schering Corporation |
Neuartige Verbindungen als Hemmer von Hepatitis C-Virus NS3-Serinprotease
|
US7816326B2
(en)
|
2004-02-27 |
2010-10-19 |
Schering Corporation |
Sulfur compounds as inhibitors of hepatitis C virus NS3 serine protease
|
ES2532433T3
(es)
*
|
2004-03-12 |
2015-03-26 |
Vertex Pharmaceuticals Incorporated |
Proceso y productos intermedios para la preparación de inhibidores de la acetal caspasa aspártica
|
EP1745064B1
(de)
|
2004-04-15 |
2011-01-05 |
Proteolix, Inc. |
Verbindungen zur proteasomenzymhemmung
|
US8198270B2
(en)
*
|
2004-04-15 |
2012-06-12 |
Onyx Therapeutics, Inc. |
Compounds for proteasome enzyme inhibition
|
CA2565407A1
(en)
*
|
2004-05-10 |
2005-11-24 |
Proteolix, Inc. |
Compounds for enzyme inhibition
|
CN1984922A
(zh)
|
2004-05-20 |
2007-06-20 |
先灵公司 |
用作丙型肝炎病毒ns3丝氨酸蛋白酶抑制剂的取代脯氨酸
|
AP2461A
(en)
|
2004-07-16 |
2012-09-14 |
Gilead Sciences Inc |
Antiviral compounds
|
JP4914355B2
(ja)
|
2004-07-20 |
2012-04-11 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
C型肝炎インヒビターペプチド類似体
|
UY29016A1
(es)
|
2004-07-20 |
2006-02-24 |
Boehringer Ingelheim Int |
Analogos de dipeptidos inhibidores de la hepatitis c
|
US7597884B2
(en)
|
2004-08-09 |
2009-10-06 |
Alios Biopharma, Inc. |
Hyperglycosylated polypeptide variants and methods of use
|
EP1789074A4
(de)
*
|
2004-08-09 |
2009-08-12 |
Alios Biopharma Inc |
Synthetische hyperglycosylierte, protease-resistente polypeptid-varianten, orale formulierungen und anwendungsverfahren dafür
|
CN101068828A
(zh)
|
2004-08-27 |
2007-11-07 |
先灵公司 |
用作丙型肝炎病毒ns3丝氨酸蛋白酶抑制剂的酰基磺酰胺化合物
|
MX2007003085A
(es)
|
2004-09-14 |
2007-08-02 |
Pharmasset Inc |
Preparacion de 2'-fluoro-2'-alquilo sustituido u otras ribofuranosil pirimidinas y purinas opcionalmente sustituidas y sus derivados.
|
SG155967A1
(en)
|
2004-10-01 |
2009-10-29 |
Vertex Pharma |
Hcv ns3-ns4a protease inhibition
|
US7659263B2
(en)
|
2004-11-12 |
2010-02-09 |
Japan Tobacco Inc. |
Thienopyrrole compound and use thereof as HCV polymerase inhibitor
|
US7323447B2
(en)
|
2005-02-08 |
2008-01-29 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7468383B2
(en)
|
2005-02-11 |
2008-12-23 |
Cephalon, Inc. |
Proteasome inhibitors and methods of using the same
|
US7592336B2
(en)
|
2005-05-10 |
2009-09-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
ES2415742T3
(es)
|
2005-05-13 |
2013-07-26 |
Vertex Pharmaceuticals (Canada) Incorporated |
Compuestos y procedimientos para el tratamiento o prevención de infecciones por flavivirus
|
EP1881828A4
(de)
*
|
2005-05-20 |
2009-06-03 |
Valeant Res & Dev |
Behandlung von hcv mittels subtherapeutischer dosen von ribavirin
|
AU2006252553B2
(en)
|
2005-06-02 |
2012-03-29 |
Merck Sharp & Dohme Corp. |
Combination of HCV protease inhibitors with a surfactant
|
US20060276404A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Anima Ghosal |
Medicaments and methods combining a HCV protease inhibitor and an AKR competitor
|
PL1891089T3
(pl)
|
2005-06-02 |
2015-05-29 |
Merck Sharp & Dohme |
Inhibitory proteazy HCV w połączeniu z pokarmem
|
US20070237818A1
(en)
*
|
2005-06-02 |
2007-10-11 |
Malcolm Bruce A |
Controlled-release formulation of HCV protease inhibitor and methods using the same
|
CN101242842A
(zh)
|
2005-06-17 |
2008-08-13 |
诺瓦提斯公司 |
Sanglifehrin在hcv中的用途
|
US7608592B2
(en)
*
|
2005-06-30 |
2009-10-27 |
Virobay, Inc. |
HCV inhibitors
|
US7601686B2
(en)
|
2005-07-11 |
2009-10-13 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
EP2305696A3
(de)
|
2005-07-25 |
2011-10-12 |
Intermune, Inc. |
Makrocyclische Inhibitoren der Replikation des Hepatitis-C-Virus
|
WO2007014924A1
(en)
|
2005-07-29 |
2007-02-08 |
Tibotec Pharmaceuticals Ltd. |
Macrocyclic inhibitors of hepatitis c virus
|
JO2768B1
(en)
|
2005-07-29 |
2014-03-15 |
تيبوتيك فارماسيوتيكالز ليمتد |
Large cyclic inhibitors of hepatitis C virus
|
PL1919904T3
(pl)
|
2005-07-29 |
2014-06-30 |
Janssen R&D Ireland |
Makrocykliczne inhibitory wirusa zapalenia wątroby typu C
|
PE20070211A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
MY144895A
(en)
|
2005-07-29 |
2011-11-30 |
Tibotec Pharm Ltd |
Macrocylic inhibitors of hepatitis c virus
|
DK1919898T3
(da)
|
2005-07-29 |
2011-05-02 |
Tibotec Pharm Ltd |
Makrocykliske inhibitorer af hepatitis-C-virus
|
DK1912997T3
(da)
|
2005-07-29 |
2012-01-02 |
Tibotec Pharm Ltd |
Makrocycliske inhibitorer af hepatitis C virus
|
PE20070210A1
(es)
|
2005-07-29 |
2007-04-16 |
Tibotec Pharm Ltd |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
CN101273028B
(zh)
|
2005-07-29 |
2013-08-21 |
泰博特克药品有限公司 |
丙型肝炎病毒的大环抑制剂
|
WO2007016476A2
(en)
*
|
2005-08-01 |
2007-02-08 |
Phenomix Corporation |
Hepatitis c serine protease inhibitors and uses therefor
|
CA2617679A1
(en)
|
2005-08-02 |
2007-02-08 |
Steve Lyons |
Inhibitors of serine proteases
|
NZ566049A
(en)
*
|
2005-08-19 |
2011-07-29 |
Vertex Pharma |
Processes and intermediates
|
US8399615B2
(en)
|
2005-08-19 |
2013-03-19 |
Vertex Pharmaceuticals Incorporated |
Processes and intermediates
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
US7964624B1
(en)
|
2005-08-26 |
2011-06-21 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases
|
CN102304075A
(zh)
*
|
2005-10-11 |
2012-01-04 |
因特蒙公司 |
病毒复制抑制剂
|
KR20080056295A
(ko)
|
2005-10-11 |
2008-06-20 |
인터뮨, 인크. |
C형 간염 바이러스 복제를 억제하기 위한 화합물 및 방법
|
US7772183B2
(en)
|
2005-10-12 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7741281B2
(en)
|
2005-11-03 |
2010-06-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
PT2623113T
(pt)
|
2005-11-09 |
2017-07-14 |
Onyx Therapeutics Inc |
Compostos para inibição de enzimas
|
US7705138B2
(en)
|
2005-11-11 |
2010-04-27 |
Vertex Pharmaceuticals Incorporated |
Hepatitis C virus variants
|
EP2392588A3
(de)
|
2005-11-11 |
2012-03-07 |
Vertex Pharmaceuticals Incorporated |
Hepatitis-C-Virusvarianten
|
CA2634743C
(en)
*
|
2005-12-23 |
2014-07-29 |
Zealand Pharma A/S |
Modified lysine-mimetic compounds
|
WO2007089618A2
(en)
*
|
2006-01-27 |
2007-08-09 |
Phenomix Corporation |
Hepatitis c serine protease inhibitors and uses therefor
|
CA2641859A1
(en)
*
|
2006-02-09 |
2007-08-16 |
Schering Corporation |
Combinations comprising hcv protease inhibitor(s) and hcv polymerase inhibitor(s), and methods of treatment related thereto
|
AU2007217355B2
(en)
|
2006-02-27 |
2012-06-21 |
Vertex Pharmaceuticals Incorporated |
Co-crystals comprising VX-950 and pharmaceutical compositions comprising the same
|
MX2008011868A
(es)
*
|
2006-03-16 |
2008-12-15 |
Vertex Pharma |
Inhibidores deuterados de la proteasa de la hepatitis c.
|
NZ571826A
(en)
|
2006-04-11 |
2012-01-12 |
Novartis Ag |
HCV/HIV inhibitors and their uses
|
US8017612B2
(en)
|
2006-04-18 |
2011-09-13 |
Japan Tobacco Inc. |
Piperazine compound and use thereof as a HCV polymerase inhibitor
|
JP2009538327A
(ja)
|
2006-05-23 |
2009-11-05 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
チャネル活性化プロテアーゼ阻害剤である化合物および組成物
|
SI2041158T1
(sl)
*
|
2006-06-19 |
2013-09-30 |
Onyx Therapeutics, Inc. |
Peptidni epoksiketoni za inhibicijo proteasomov
|
EP2049474B1
(de)
|
2006-07-11 |
2015-11-04 |
Bristol-Myers Squibb Company |
Hemmer des hepatitis-c-virus
|
EP1886685A1
(de)
|
2006-08-11 |
2008-02-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methoden, Verwendungen und Zusammensetzungen zur Modulation der Replikation von HCV durch Aktivierung oder Hemmung des Farnesoid X Rezeptors
|
WO2008063727A2
(en)
*
|
2006-08-21 |
2008-05-29 |
United Therapeutics Corporation |
Combination therapy for treatment of viral infections
|
EP2057278A2
(de)
*
|
2006-08-28 |
2009-05-13 |
Vertex Pharmceuticals Incorporated |
Verfahren zur identifikation von protease-hemmern
|
US8343477B2
(en)
|
2006-11-01 |
2013-01-01 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus
|
US7772180B2
(en)
|
2006-11-09 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
EA201101492A1
(ru)
|
2006-11-15 |
2012-09-28 |
Вирокем Фарма Инк. |
Аналоги тиофена для лечения или предупреждения флавивирусных инфекций
|
US7763584B2
(en)
|
2006-11-16 |
2010-07-27 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US8003604B2
(en)
|
2006-11-16 |
2011-08-23 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7888464B2
(en)
|
2006-11-16 |
2011-02-15 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
CA2673111A1
(en)
*
|
2006-12-07 |
2008-06-19 |
Schering Corporation |
Ph sensitive matrix formulation
|
EP2468724B1
(de)
|
2006-12-21 |
2015-11-18 |
Zealand Pharma A/S |
Synthese von Pyrrolidinverbindungen
|
AU2007339382B2
(en)
|
2006-12-22 |
2013-05-02 |
Merck Sharp & Dohme Llc |
4,5-ring annulated indole derivatives for treating or preventing of HCV and related viral infections
|
MX2009006877A
(es)
|
2006-12-22 |
2009-09-28 |
Schering Corp |
Derivados indolicos con anillo unido en las posiciones 5,6 y metodos de uso de los mismos.
|
EP2064181A1
(de)
|
2006-12-22 |
2009-06-03 |
Schering Corporation |
4,5-ring-annulierte indol-derivate zur behandlung oder prävention von hcv und verwandten virusinfektionen
|
EP2118091B1
(de)
|
2007-02-08 |
2015-04-15 |
Janssen Sciences Ireland UC |
Pyrimidin-substituierte makrozyklische hcv-hemmer
|
EA016327B1
(ru)
*
|
2007-02-09 |
2012-04-30 |
Айрм Ллк |
Соединения и композиции в качестве ингибиторов протеазы, активирующей каналы
|
ES2379905T3
(es)
*
|
2007-02-27 |
2012-05-04 |
Vertex Pharmceuticals Incorporated |
Co-cristales y composiciones farmacéuticas que los comprenden
|
US8575208B2
(en)
|
2007-02-27 |
2013-11-05 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases
|
AU2008219622A1
(en)
|
2007-02-28 |
2008-09-04 |
Conatus Pharmaceuticals, Inc. |
Methods for the treatment of liver diseases using specified matrix metalloproteinase (MMP) inhibitors
|
WO2008106167A1
(en)
*
|
2007-02-28 |
2008-09-04 |
Conatus Pharmaceuticals, Inc. |
Combination therapy comprising matrix metalloproteinase inhibitors and caspase inhibitors for the treatment of liver diseases
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
ATE548044T1
(de)
|
2007-05-04 |
2012-03-15 |
Vertex Pharma |
Kombinationstherapie zur behandlung von hiv- infektionen
|
US8513186B2
(en)
|
2007-06-29 |
2013-08-20 |
Gilead Sciences, Inc. |
Antiviral compounds
|
AR067442A1
(es)
|
2007-06-29 |
2009-10-14 |
Gilead Sciences Inc |
Compuestos antivirales
|
EP2195317B1
(de)
|
2007-08-29 |
2012-01-18 |
Schering Corporation |
2,3-substituierte azaindolderivate zur behandlung von virusinfektionen
|
PE20090995A1
(es)
|
2007-08-29 |
2009-08-03 |
Schering Corp |
Derivados indolicos 2,3-sustituidos como inhibidores del virus de la hepatitis c (vhc)
|
KR20100067652A
(ko)
|
2007-08-29 |
2010-06-21 |
쉐링 코포레이션 |
치환된 인돌 유도체 및 이의 사용방법
|
NZ583699A
(en)
*
|
2007-08-30 |
2012-04-27 |
Vertex Pharma |
Co-crystals of vx-950 (telaprevir) other components and pharmaceutical compositions comprising the same
|
GB0718575D0
(en)
|
2007-09-24 |
2007-10-31 |
Angeletti P Ist Richerche Bio |
Nucleoside derivatives as inhibitors of viral polymerases
|
TWI501773B
(zh)
|
2007-10-04 |
2015-10-01 |
Onyx Therapeutics Inc |
結晶肽環氧酮蛋白酶抑制劑以及胺基酸酮環氧化物之合成
|
US8377928B2
(en)
|
2007-11-16 |
2013-02-19 |
Merck Sharp & Dohme Corp. |
3-aminosulfonyl substituted indole derivatives and methods of use thereof
|
EP2222660B1
(de)
|
2007-11-16 |
2014-03-26 |
Merck Sharp & Dohme Corp. |
3-heterocyclylsubstituierte indolderivate und verfahren zu deren anwendung
|
US8202996B2
(en)
|
2007-12-21 |
2012-06-19 |
Bristol-Myers Squibb Company |
Crystalline forms of N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-4-((7-chloro-4-methoxy-1-isoquinolinyl)oxy)-N- ((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-L-prolinamide
|
WO2009099596A2
(en)
|
2008-02-04 |
2009-08-13 |
Idenix Pharamaceuticals, Inc. |
Macrocyclic serine protease inhibitors
|
TW200946541A
(en)
|
2008-03-27 |
2009-11-16 |
Idenix Pharmaceuticals Inc |
Solid forms of an anti-HIV phosphoindole compound
|
US8163921B2
(en)
|
2008-04-16 |
2012-04-24 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
WO2009148923A1
(en)
|
2008-05-29 |
2009-12-10 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
US7964560B2
(en)
|
2008-05-29 |
2011-06-21 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
JP5580814B2
(ja)
|
2008-06-13 |
2014-08-27 |
メルク・シャープ・アンド・ドーム・コーポレーション |
3環式インドール誘導体およびその使用方法
|
KR20110065440A
(ko)
|
2008-07-02 |
2011-06-15 |
아이데닉스 파마슈티칼스, 인코포레이티드 |
바이러스 감염의 치료를 위한 화합물 및 제약 조성물
|
TW201019939A
(en)
|
2008-08-20 |
2010-06-01 |
Schering Corp |
Azo-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
AU2009282571B2
(en)
|
2008-08-20 |
2014-12-11 |
Merck Sharp & Dohme Corp. |
Ethynyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
AU2009282567B2
(en)
|
2008-08-20 |
2014-10-02 |
Merck Sharp & Dohme Corp. |
Substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
AU2009282574B2
(en)
|
2008-08-20 |
2014-08-21 |
Merck Sharp & Dohme Corp. |
Ethenyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
US8207341B2
(en)
|
2008-09-04 |
2012-06-26 |
Bristol-Myers Squibb Company |
Process or synthesizing substituted isoquinolines
|
US8044087B2
(en)
|
2008-09-29 |
2011-10-25 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US8563505B2
(en)
|
2008-09-29 |
2013-10-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
EP3025727A1
(de)
|
2008-10-02 |
2016-06-01 |
The J. David Gladstone Institutes |
Verfahren zur behandlung von lebererkrankungen
|
BRPI0919668A2
(pt)
|
2008-10-21 |
2018-05-29 |
Onyx Therapeutics, Inc. |
terapia de combinação com epóxi-cetonas de peptídeo
|
JP5762971B2
(ja)
|
2008-12-03 |
2015-08-12 |
プレシディオ ファーマシューティカルズ インコーポレイテッド |
Hcvns5aの阻害剤
|
KR20110098779A
(ko)
|
2008-12-03 |
2011-09-01 |
프레시디오 파마슈티칼스, 인코포레이티드 |
Hcv ns5a의 억제제
|
US8283310B2
(en)
|
2008-12-15 |
2012-10-09 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US8914351B2
(en)
|
2008-12-16 |
2014-12-16 |
Clinton A. Krislov |
Method and system for secure automated document registration from social media networks
|
US8589372B2
(en)
|
2008-12-16 |
2013-11-19 |
Clinton A. Krislov |
Method and system for automated document registration with cloud computing
|
KR20110114582A
(ko)
*
|
2008-12-19 |
2011-10-19 |
길리애드 사이언시즈, 인코포레이티드 |
Hcv ns3 프로테아제 억제제
|
NZ593647A
(en)
|
2008-12-23 |
2013-08-30 |
Gilead Pharmasset Llc |
Synthesis of purine nucleosides
|
EP2376514A2
(de)
|
2008-12-23 |
2011-10-19 |
Pharmasset, Inc. |
Nukleosidanaloga
|
MX2011006891A
(es)
|
2008-12-23 |
2011-10-06 |
Pharmasset Inc |
Fosforamidatos de nucleosidos.
|
US8102720B2
(en)
*
|
2009-02-02 |
2012-01-24 |
Qualcomm Incorporated |
System and method of pulse generation
|
EP2403860B1
(de)
|
2009-03-04 |
2015-11-04 |
IDENIX Pharmaceuticals, Inc. |
Phosphothiophene und phosphothiazole als hcv polymerase inhibitoren
|
US8975247B2
(en)
|
2009-03-18 |
2015-03-10 |
The Board Of Trustees Of The Leland Stanford Junion University |
Methods and compositions of treating a flaviviridae family viral infection
|
AR075899A1
(es)
|
2009-03-20 |
2011-05-04 |
Onyx Therapeutics Inc |
Tripeptidos epoxicetonas cristalinos inhibidores de proteasa
|
JP5735482B2
(ja)
|
2009-03-27 |
2015-06-17 |
プレシディオ ファーマシューティカルズ インコーポレイテッド |
縮合環のc型肝炎阻害剤
|
WO2010117936A1
(en)
|
2009-04-06 |
2010-10-14 |
Schering Corporation |
Combinations of a hcv inhibitor such as bicyclic pyrrole derivatives and a therapeutic agent
|
EP2416765B1
(de)
|
2009-04-06 |
2016-03-30 |
PTC Therapeutics, Inc. |
Kombinationen von hcv-inhibitor und therapeutischen mitteln
|
EP2417134B1
(de)
|
2009-04-08 |
2017-05-17 |
Idenix Pharmaceuticals LLC. |
Macrocyclische serinproteaseinhibitoren
|
US8512690B2
(en)
|
2009-04-10 |
2013-08-20 |
Novartis Ag |
Derivatised proline containing peptide compounds as protease inhibitors
|
US20110182850A1
(en)
|
2009-04-10 |
2011-07-28 |
Trixi Brandl |
Organic compounds and their uses
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
TWI576352B
(zh)
|
2009-05-20 |
2017-04-01 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
CA2763140A1
(en)
|
2009-05-29 |
2010-12-02 |
Schering Corporation |
Antiviral compounds composed of three linked aryl moieties to treat diseases such as hepatitis c
|
WO2011017389A1
(en)
|
2009-08-05 |
2011-02-10 |
Idenix Pharmaceuticals, Inc. |
Macrocyclic serine protease inhibitors useful against viral infections, particularly hcv
|
US8389560B2
(en)
|
2009-09-15 |
2013-03-05 |
Taigen Biotechnology Co., Ltd. |
HCV protease inhibitors
|
US8853147B2
(en)
|
2009-11-13 |
2014-10-07 |
Onyx Therapeutics, Inc. |
Use of peptide epoxyketones for metastasis suppression
|
US20110117055A1
(en)
|
2009-11-19 |
2011-05-19 |
Macdonald James E |
Methods of Treating Hepatitis C Virus with Oxoacetamide Compounds
|
JP2013512246A
(ja)
|
2009-11-25 |
2013-04-11 |
メルク・シャープ・アンド・ドーム・コーポレーション |
ウイルス疾患治療に有用な縮合型三環式化合物およびその誘導体
|
WO2011068715A1
(en)
|
2009-11-25 |
2011-06-09 |
Vertex Pharmaceuticals Incorporated |
5-alkynyl-thiophene-2-carboxylic acid derivatives and their use for the treatment or prevention of flavivirus infections
|
CN102822175A
(zh)
|
2009-12-18 |
2012-12-12 |
埃迪尼克斯医药公司 |
5,5-稠合的亚芳基或亚杂芳基丙型肝炎病毒抑制剂
|
CA2785488A1
(en)
|
2009-12-22 |
2011-07-21 |
Merck Sharp & Dohme Corp. |
Fused tricyclic compounds and methods of use thereof for the treatment of viral diseases
|
CN102725300B
(zh)
|
2009-12-22 |
2015-03-11 |
赛福伦公司 |
蛋白酶体抑制剂及其制备、纯化、和应用的方法
|
JP2013515746A
(ja)
|
2009-12-24 |
2013-05-09 |
ヴァーテックス ファーマシューティカルズ、 インコーポレイテッド |
フラビウイルス感染症の治療又は予防のための類似体
|
US8653025B2
(en)
|
2010-01-27 |
2014-02-18 |
AB Pharma Ltd. |
Polyheterocyclic compounds highly potent as HCV inhibitors
|
EP2536410B1
(de)
|
2010-02-18 |
2015-09-23 |
Merck Sharp & Dohme Corp. |
Substituierte pyrimidinderivate und ihre verwendung bei der behandlung viraler infektionen
|
MX2012010017A
(es)
|
2010-03-01 |
2012-10-01 |
Onyx Therapeutics Inc |
Compuestos de para la inhibicion de inmunoproteasomas.
|
WO2011112516A1
(en)
|
2010-03-08 |
2011-09-15 |
Ico Therapeutics Inc. |
Treating and preventing hepatitis c virus infection using c-raf kinase antisense oligonucleotides
|
MA34147B1
(fr)
|
2010-03-09 |
2013-04-03 |
Merck Sharp & Dohme |
Composes tricycliques fusionnes de silyle et leurs methodes d'utilisation dans le cadre du traitement de maladies virales
|
EP2550262A1
(de)
|
2010-03-24 |
2013-01-30 |
Vertex Pharmaceuticals Incorporated |
Analoga zur behandlung oder vorbeugung von flavivirus-infektionen
|
WO2011119853A1
(en)
|
2010-03-24 |
2011-09-29 |
Vertex Pharmaceuticals Incorporated |
Analogues for the treatment or prevention of flavivirus infections
|
JP2013522377A
(ja)
|
2010-03-24 |
2013-06-13 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
フラビウイルス感染を処置または予防するためのアナログ
|
TW201141857A
(en)
|
2010-03-24 |
2011-12-01 |
Vertex Pharma |
Analogues for the treatment or prevention of flavivirus infections
|
AU2011235112B2
(en)
|
2010-03-31 |
2015-07-09 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
MX2012011222A
(es)
|
2010-04-01 |
2013-01-18 |
Centre Nat Rech Scient |
Compuestos y composiciones farmaceuticas para el tratamiento de infecciones virales.
|
MX2012011604A
(es)
|
2010-04-07 |
2013-02-27 |
Onyx Therapeutics Inc |
Inhibidor de inmunoproteasoma de péptido epoxicetona cristalino.
|
EP2575866A4
(de)
|
2010-05-24 |
2013-10-16 |
Presidio Pharmaceuticals Inc |
Hcv-ns5a-shemmer
|
WO2011156545A1
(en)
|
2010-06-09 |
2011-12-15 |
Vertex Pharmaceuticals Incorporated |
Viral dynamic model for hcv combination therapy
|
EP2582717A2
(de)
|
2010-06-15 |
2013-04-24 |
Vertex Pharmaceuticals Incorporated |
Hcv-ns5b-polymerasemutanten
|
EP2585447A2
(de)
|
2010-06-28 |
2013-05-01 |
Vertex Pharmaceuticals Incorporated |
Verbindungen und verfahren zur behandlung oder vorbeugung von flavivirus-infektionen
|
WO2012006070A1
(en)
|
2010-06-28 |
2012-01-12 |
Vertex Pharmaceuticals Incorporated |
Compounds and methods for the treatment or prevention of flavivirus infections
|
WO2012006060A1
(en)
|
2010-06-28 |
2012-01-12 |
Vertex Pharmaceuticals Incorporated |
Compounds and methods for the treatment or prevention of flavivirus infections
|
EP2598149A4
(de)
|
2010-07-26 |
2014-09-10 |
Merck Sharp & Dohme |
Substituierte biphenylenverbindungen und verfahren zu ihrer verwendung zur behandlung von virenerkrankungen
|
WO2012020036A1
(en)
|
2010-08-13 |
2012-02-16 |
F. Hoffmann-La Roche Ag |
Hepatitis c virus inhibitors
|
CN103153978A
(zh)
|
2010-08-17 |
2013-06-12 |
沃泰克斯药物股份有限公司 |
用于治疗或预防黄病毒科病毒感染的化合物和方法
|
JP2013540122A
(ja)
|
2010-09-29 |
2013-10-31 |
メルク・シャープ・エンド・ドーム・コーポレイション |
縮合四環式化合物誘導体およびウィルス疾患治療のためのそれの使用方法
|
MX2013003945A
(es)
|
2010-10-08 |
2013-06-05 |
Novartis Ag |
Formulaciones de vitamina e como inhibidoras de sulfamida ns3.
|
CN103328466B
(zh)
|
2010-11-01 |
2016-08-03 |
Rfs制药公司 |
Hcv ns3蛋白酶抑制剂
|
AU2011336632B2
(en)
|
2010-11-30 |
2015-09-03 |
Gilead Pharmasset Llc |
Compounds
|
AR085352A1
(es)
|
2011-02-10 |
2013-09-25 |
Idenix Pharmaceuticals Inc |
Inhibidores macrociclicos de serina proteasa, sus composiciones farmaceuticas y su uso para tratar infecciones por hcv
|
WO2012107589A1
(en)
|
2011-02-11 |
2012-08-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment and prevention of hcv infections
|
WO2012123298A1
(en)
|
2011-03-11 |
2012-09-20 |
F. Hoffmann-La Roche Ag |
Antiviral compounds
|
US9243025B2
(en)
|
2011-03-31 |
2016-01-26 |
Idenix Pharmaceuticals, Llc |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
US9156872B2
(en)
|
2011-04-13 |
2015-10-13 |
Merck Sharp & Dohme Corp. |
2′-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
US8957203B2
(en)
|
2011-05-05 |
2015-02-17 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US10501493B2
(en)
|
2011-05-27 |
2019-12-10 |
Rqx Pharmaceuticals, Inc. |
Broad spectrum antibiotics
|
US8691757B2
(en)
|
2011-06-15 |
2014-04-08 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
WO2012171332A1
(zh)
|
2011-06-16 |
2012-12-20 |
爱博新药研发(上海)有限公司 |
抑制丙型肝炎病毒的大环状杂环化合物及其制备和应用
|
WO2012175700A1
(en)
|
2011-06-23 |
2012-12-27 |
Digna Biotech, S. L. |
Treatment of chronic hepatitis c with ifn-a5 combined with ifn-a2b in a cohort of patients
|
WO2012175581A1
(en)
|
2011-06-24 |
2012-12-27 |
F. Hoffmann-La Roche Ag |
Antiviral compounds
|
CN102807607B
(zh)
*
|
2011-07-22 |
2013-10-23 |
爱博新药研发(上海)有限公司 |
抑制丙肝病毒的稠环杂环类化合物、其中间体及其应用
|
WO2013016499A1
(en)
|
2011-07-26 |
2013-01-31 |
Vertex Pharmaceuticals Incorporated |
Methods for preparation of thiophene compounds
|
WO2013016491A1
(en)
|
2011-07-26 |
2013-01-31 |
Vertex Pharmaceuticals Incorporated |
Thiophene compounds
|
WO2013033900A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of viral diseases
|
WO2013033899A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases
|
WO2013033901A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Heterocyclic-substituted benzofuran derivatives and methods of use thereof for the treatment of viral diseases
|
WO2013039920A1
(en)
|
2011-09-12 |
2013-03-21 |
Idenix Pharmaceuticals, Inc. |
Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections
|
WO2013039855A1
(en)
|
2011-09-12 |
2013-03-21 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
EP2755981A4
(de)
|
2011-09-14 |
2015-03-25 |
Merck Sharp & Dohme |
Silylhaltige heterocyclische derivate sowie verfahren zu ihrer verwendung zur behandlung von virenerkrankungen
|
CN103917541B
(zh)
|
2011-10-10 |
2016-08-17 |
弗·哈夫曼-拉罗切有限公司 |
抗病毒化合物
|
TW201331221A
(zh)
|
2011-10-14 |
2013-08-01 |
Idenix Pharmaceuticals Inc |
嘌呤核苷酸化合物類之經取代的3’,5’-環磷酸酯及用於治療病毒感染之醫藥組成物
|
US20130123276A1
(en)
|
2011-11-14 |
2013-05-16 |
Sven Ruf |
Use of telaprevir and related compounds in atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
CN104185420B
(zh)
|
2011-11-30 |
2017-06-09 |
埃默里大学 |
用于治疗或预防逆转录病毒和其它病毒感染的抗病毒jak抑制剂
|
WO2013086133A1
(en)
|
2011-12-06 |
2013-06-13 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for treating viral diseases
|
CA2855574A1
(en)
|
2011-12-16 |
2013-06-20 |
F. Hoffmann-La Roche Ag |
Inhibitors of hcv ns5a
|
KR101687084B1
(ko)
|
2011-12-20 |
2016-12-15 |
리보사이언스 엘엘씨 |
Hcv rna 복제의 억제제로서 4'-아지도, 3'-플루오로 치환된 뉴클레오시드 유도체
|
MX350809B
(es)
|
2011-12-20 |
2017-09-20 |
Riboscience Llc |
Derivados nucleósidos con sustitución 2',4'-difluoro-2'-metilo como inhibidores de la replicación del arn del vhc.
|
US8809354B2
(en)
|
2011-12-31 |
2014-08-19 |
Sheikh Riazuddin |
3-amino-2-(4-nitrophenyl)-4-(3H)-quinazolinone or derivatives thereof for treating or preventing antiviral infections
|
CN104039774A
(zh)
|
2012-01-12 |
2014-09-10 |
Rfs制药公司 |
Hcv ns3蛋白酶抑制剂
|
US20130217644A1
(en)
|
2012-02-13 |
2013-08-22 |
Idenix Pharmaceuticals, Inc. |
Pharmaceutical Compositions of 2'-C-Methyl-Guanosine, 5'-[2[(3-Hydroxy-2,2-Dimethyl-1-Oxopropyl)Thio]Ethyl N-(Phenylmethyl)Phosphoramidate]
|
EA201491511A1
(ru)
|
2012-02-16 |
2014-12-30 |
АрКьюИкс ФАРМАСЬЮТИКАЛС, ИНК. |
Линейные пептидные антибиотики
|
US9090559B2
(en)
|
2012-02-24 |
2015-07-28 |
Hoffmann-La Roche Inc. |
Antiviral compounds
|
WO2013142157A1
(en)
|
2012-03-22 |
2013-09-26 |
Alios Biopharma, Inc. |
Pharmaceutical combinations comprising a thionucleotide analog
|
EP2852605B1
(de)
|
2012-05-22 |
2018-01-31 |
Idenix Pharmaceuticals LLC |
3',5'-cyclische phosphat-prodrugs für hcv-infektion
|
WO2013177188A1
(en)
|
2012-05-22 |
2013-11-28 |
Idenix Pharmaceuticals, Inc. |
3',5'-cyclic phosphoramidate prodrugs for hcv infection
|
AU2013266393B2
(en)
|
2012-05-22 |
2017-09-28 |
Idenix Pharmaceuticals Llc |
D-amino acid compounds for liver disease
|
US20140010783A1
(en)
|
2012-07-06 |
2014-01-09 |
Hoffmann-La Roche Inc. |
Antiviral compounds
|
WO2014011695A2
(en)
|
2012-07-09 |
2014-01-16 |
Onyx Therapeutics, Inc. |
Prodrugs of peptide epoxy ketone protease inhibitors
|
WO2014053533A1
(en)
|
2012-10-05 |
2014-04-10 |
Sanofi |
Use of substituted 3-heteroaroylamino-propionic acid derivatives as pharmaceuticals for prevention/treatment of atrial fibrillation
|
GEP201706723B
(en)
|
2012-10-08 |
2017-08-25 |
Idenix Pharmaceuticals Llk |
2'-chloro nucleoside analogs for hcv infection
|
JP6154474B2
(ja)
|
2012-10-19 |
2017-06-28 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
C型肝炎ウイルス阻害剤
|
WO2014063019A1
(en)
|
2012-10-19 |
2014-04-24 |
Idenix Pharmaceuticals, Inc. |
Dinucleotide compounds for hcv infection
|
WO2014066239A1
(en)
|
2012-10-22 |
2014-05-01 |
Idenix Pharmaceuticals, Inc. |
2',4'-bridged nucleosides for hcv infection
|
US10260089B2
(en)
|
2012-10-29 |
2019-04-16 |
The Research Foundation Of The State University Of New York |
Compositions and methods for recognition of RNA using triple helical peptide nucleic acids
|
US9643999B2
(en)
|
2012-11-02 |
2017-05-09 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US9598433B2
(en)
|
2012-11-02 |
2017-03-21 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
WO2014071007A1
(en)
|
2012-11-02 |
2014-05-08 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
WO2014070974A1
(en)
|
2012-11-05 |
2014-05-08 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
US20140140951A1
(en)
|
2012-11-14 |
2014-05-22 |
Idenix Pharmaceuticals, Inc. |
D-Alanine Ester of Rp-Nucleoside Analog
|
WO2014078436A1
(en)
|
2012-11-14 |
2014-05-22 |
Idenix Pharmaceuticals, Inc. |
D-alanine ester of sp-nucleoside analog
|
WO2014099941A1
(en)
|
2012-12-19 |
2014-06-26 |
Idenix Pharmaceuticals, Inc. |
4'-fluoro nucleosides for the treatment of hcv
|
CA2892589A1
(en)
|
2013-01-23 |
2014-07-31 |
F. Hoffmann-La Roche Ag |
Antiviral triazole derivatives
|
US20150065439A1
(en)
|
2013-02-28 |
2015-03-05 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions
|
US9339541B2
(en)
|
2013-03-04 |
2016-05-17 |
Merck Sharp & Dohme Corp. |
Thiophosphate nucleosides for the treatment of HCV
|
WO2014137926A1
(en)
|
2013-03-04 |
2014-09-12 |
Idenix Pharmaceuticals, Inc. |
3'-deoxy nucleosides for the treatment of hcv
|
CN105008350B
(zh)
|
2013-03-05 |
2018-05-08 |
弗·哈夫曼-拉罗切有限公司 |
抗病毒化合物
|
WO2014137869A1
(en)
|
2013-03-07 |
2014-09-12 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
WO2014165542A1
(en)
|
2013-04-01 |
2014-10-09 |
Idenix Pharmaceuticals, Inc. |
2',4'-fluoro nucleosides for the treatment of hcv
|
US9249176B2
(en)
|
2013-05-16 |
2016-02-02 |
Riboscience Llc |
4′-azido, 3′-deoxy-3′-fluoro substituted nucleoside derivatives as inhibitors of HCV RNA replication
|
US20180200280A1
(en)
|
2013-05-16 |
2018-07-19 |
Riboscience Llc |
4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication
|
AU2014265293B2
(en)
|
2013-05-16 |
2019-07-18 |
Riboscience Llc |
4'-Fluoro-2'-methyl substituted nucleoside derivatives
|
EP3004130B1
(de)
|
2013-06-05 |
2019-08-07 |
Idenix Pharmaceuticals LLC. |
1',4'-thionukleoside zur behandlung von hcv
|
WO2015017713A1
(en)
|
2013-08-01 |
2015-02-05 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
|
MX2016001927A
(es)
*
|
2013-08-14 |
2016-09-08 |
Rqx Pharmaceuticals Inc |
Antibióticos de péptidos lineales.
|
NZ716840A
(en)
|
2013-08-27 |
2017-06-30 |
Gilead Pharmasset Llc |
Combination formulation of two antiviral compounds
|
WO2015042375A1
(en)
|
2013-09-20 |
2015-03-26 |
Idenix Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
WO2015061683A1
(en)
|
2013-10-25 |
2015-04-30 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate and d-alanine thiophosphoramidate pronucleotides of nucleoside compounds useful for the treatment of hcv
|
US10167298B2
(en)
|
2013-10-30 |
2019-01-01 |
Merck Sharp & Dohme Corp. |
Pseudopolymorphs of an HCV NS5A inhibitor and uses thereof
|
WO2015066370A1
(en)
|
2013-11-01 |
2015-05-07 |
Idenix Pharmaceuticals, Inc. |
D-alanine phosphoramidate pronucleotides of 2'-methyl 2'-fluoro guanosine nucleoside compounds for the treatment of hcv
|
WO2015081297A1
(en)
|
2013-11-27 |
2015-06-04 |
Idenix Pharmaceuticals, Inc. |
2'-dichloro and 2'-fluoro-2'-chloro nucleoside analogues for hcv infection
|
US10683321B2
(en)
|
2013-12-18 |
2020-06-16 |
Idenix Pharmaceuticals Llc |
4′-or nucleosides for the treatment of HCV
|
EP2899207A1
(de)
|
2014-01-28 |
2015-07-29 |
Amikana.Biologics |
Neues Verfahren zum Testen von HCV-Proteasehemmung
|
WO2015134780A1
(en)
|
2014-03-05 |
2015-09-11 |
Idenix Pharmaceuticals, Inc. |
Solid prodrug forms of 2'-chloro-2'-methyl uridine for hcv
|
EP3114122A1
(de)
|
2014-03-05 |
2017-01-11 |
Idenix Pharmaceuticals LLC |
Feste formen einer flaviviridae-virus-hemmerverbindung und salze davon
|
WO2015134561A1
(en)
|
2014-03-05 |
2015-09-11 |
Idenix Pharmaceuticals, Inc. |
Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
|
US10202411B2
(en)
|
2014-04-16 |
2019-02-12 |
Idenix Pharmaceuticals Llc |
3′-substituted methyl or alkynyl nucleosides nucleotides for the treatment of HCV
|
EP3377474B1
(de)
|
2015-11-20 |
2023-08-16 |
RQX Pharmaceuticals, Inc. |
Makrocyclische breitspektrum-antibiotika
|
CN109476637B
(zh)
|
2016-06-21 |
2022-02-01 |
奥瑞恩眼科有限责任公司 |
杂环脯氨酰胺衍生物
|
US10526315B2
(en)
|
2016-06-21 |
2020-01-07 |
Orion Ophthalmology LLC |
Carbocyclic prolinamide derivatives
|
CN109563033B
(zh)
|
2016-06-21 |
2023-04-04 |
奥瑞恩眼科有限责任公司 |
脂族脯氨酰胺衍生物
|
JP2019526563A
(ja)
*
|
2016-08-23 |
2019-09-19 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Htra1阻害剤としての新規ジフルオロケタミド誘導体
|
DK3618847T3
(da)
|
2017-05-05 |
2021-05-25 |
Boston Medical Ct Corp |
GAP-junction-modulatorer af intercellulær kommunikation og deres anvendelse til behandling af diabetisk øjensygdom
|
GB2563396B
(en)
|
2017-06-12 |
2020-09-23 |
Ustav Organicke Chemie A Biochemie Av Cr V V I |
Inhibitors of Rhomboid Intramembrane Proteases
|
CN111194217B
(zh)
|
2017-09-21 |
2024-01-12 |
里伯赛恩斯有限责任公司 |
作为hcv rna复制抑制剂的4’-氟-2’-甲基取代的核苷衍生物
|
KR20210098504A
(ko)
|
2018-12-04 |
2021-08-10 |
브리스톨-마이어스 스큅 컴퍼니 |
다중 동위원소체 반응 모니터링에 의한 샘플내 보정 곡선을 사용한 분석 방법
|
BR112021024010A2
(pt)
|
2019-05-28 |
2022-05-17 |
Hoffmann La Roche |
Antibióticos macrocíclicos de amplo espectro
|