EP1881828A4 - Treatment of hcv with subtherapeutic doses of ribavirin - Google Patents
Treatment of hcv with subtherapeutic doses of ribavirinInfo
- Publication number
- EP1881828A4 EP1881828A4 EP06759554A EP06759554A EP1881828A4 EP 1881828 A4 EP1881828 A4 EP 1881828A4 EP 06759554 A EP06759554 A EP 06759554A EP 06759554 A EP06759554 A EP 06759554A EP 1881828 A4 EP1881828 A4 EP 1881828A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- ribavirin
- hcv
- treatment
- subtherapeutic doses
- subtherapeutic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68341605P | 2005-05-20 | 2005-05-20 | |
PCT/US2006/018228 WO2006127289A1 (en) | 2005-05-20 | 2006-05-09 | Treatment of hcv with subtherapeutic doses of ribavirin |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1881828A1 EP1881828A1 (en) | 2008-01-30 |
EP1881828A4 true EP1881828A4 (en) | 2009-06-03 |
Family
ID=37452331
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06759554A Withdrawn EP1881828A4 (en) | 2005-05-20 | 2006-05-09 | Treatment of hcv with subtherapeutic doses of ribavirin |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP1881828A4 (en) |
WO (1) | WO2006127289A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
EP2583680A3 (en) | 2011-10-21 | 2013-06-12 | Abbvie Inc. | Mono (PSI-7977) or combination treatment of DAAs for use in treating HCV |
SE1450130A1 (en) | 2011-10-21 | 2014-05-07 | Abbvie Inc | Methods of treating hcv comprising at least two direct-acting antiviral agents, ribavirin but not interferon |
WO2013116592A1 (en) * | 2012-02-01 | 2013-08-08 | Kadmon Pharmaceuticals, Llc | Once daily treatment of hepatitis c with ribavirin and taribavirin |
CA3022119A1 (en) | 2016-04-28 | 2017-11-02 | Emory University | Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998017679A1 (en) * | 1996-10-18 | 1998-04-30 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease |
WO2000024725A1 (en) * | 1998-10-26 | 2000-05-04 | Vertex Pharmaceuticals Incorporated | Pentacyclic compounds useful as inhibitors of hepatitis c virus ns3 helicase |
WO2003101199A1 (en) * | 2002-05-31 | 2003-12-11 | Schering Corporation | Combination therapy for rna virus infections involving ribavirin and impdh inhibitors |
WO2006007693A1 (en) * | 2004-07-16 | 2006-01-26 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
WO2006039488A2 (en) * | 2004-10-01 | 2006-04-13 | Vertex Pharmaceuticals Incorporated | Hcv ns3-ns4a protease inhibition |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2268394T3 (en) * | 2002-04-01 | 2007-03-16 | Pfizer Inc. | INHIBITORS OF PIRANONA AND PIRANDIONA OF THE RNA POLYMERASE DEPENDENT ON THE RNA OF THE VIRUS OF HEPATITIS C. |
-
2006
- 2006-05-09 WO PCT/US2006/018228 patent/WO2006127289A1/en active Application Filing
- 2006-05-09 EP EP06759554A patent/EP1881828A4/en not_active Withdrawn
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998017679A1 (en) * | 1996-10-18 | 1998-04-30 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease |
WO2000024725A1 (en) * | 1998-10-26 | 2000-05-04 | Vertex Pharmaceuticals Incorporated | Pentacyclic compounds useful as inhibitors of hepatitis c virus ns3 helicase |
WO2003101199A1 (en) * | 2002-05-31 | 2003-12-11 | Schering Corporation | Combination therapy for rna virus infections involving ribavirin and impdh inhibitors |
WO2006007693A1 (en) * | 2004-07-16 | 2006-01-26 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
WO2006039488A2 (en) * | 2004-10-01 | 2006-04-13 | Vertex Pharmaceuticals Incorporated | Hcv ns3-ns4a protease inhibition |
Non-Patent Citations (3)
Title |
---|
KATO ET AL: "Steroid-Free Induction and Preemptive Antiviral Therapy for Liver Transplant Recipients With Hepatitis C: A Preliminary Report from a Prospective Randomized Study", TRANSPLANTATION PROCEEDINGS, ORLANDO, FL, US, vol. 37, no. 2, 18 April 2005 (2005-04-18), pages 1217 - 1219, XP022309764, ISSN: 0041-1345 * |
NAKA K ET AL: "Mizoribine inhibits hepatitis C virus RNA replication: Effect of combination with interferon-alpha", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 330, no. 3, 13 May 2005 (2005-05-13), pages 871 - 879, XP004833719, ISSN: 0006-291X * |
See also references of WO2006127289A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO2006127289A1 (en) | 2006-11-30 |
EP1881828A1 (en) | 2008-01-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20071031 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20090508 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 38/21 20060101ALI20090430BHEP Ipc: A61P 31/14 20060101ALI20090430BHEP Ipc: A61K 31/4196 20060101AFI20061215BHEP |
|
17Q | First examination report despatched |
Effective date: 20090911 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20120110 |