PT1071752E
(pt)
*
|
1998-04-21 |
2003-11-28 |
Micromet Ag |
Polipeptidos especificos para cd19xcd3 e suas utilizacoes
|
CN100358577C
(zh)
|
1999-05-07 |
2008-01-02 |
杰南技术公司 |
抗体在制备治疗哺乳动物自身免疫病的试剂中的用途
|
US7829064B2
(en)
|
1999-05-10 |
2010-11-09 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods
|
US8383081B2
(en)
|
1999-05-10 |
2013-02-26 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods of use
|
US8119101B2
(en)
|
1999-05-10 |
2012-02-21 |
The Ohio State University |
Anti-CD74 immunoconjugates and methods of use
|
EP1543839B1
(de)
*
|
1999-06-09 |
2017-09-20 |
Immunomedics, Inc. |
Immuntherapie von Autoimmunerkrankungen durch die Verwendung von B-zell spezifischen Antikörpern
|
DK1194167T3
(da)
|
1999-06-09 |
2009-11-16 |
Immunomedics Inc |
Immunoterapi af autoimmune sygdomme under anvendelse af B-cellespecifikke antistoffer
|
DE19962583A1
(de)
*
|
1999-12-23 |
2001-06-28 |
Mueller Hermelink Hans Konrad |
Antikörper gegen Plasmazellen
|
EP1334188B1
(de)
|
2000-11-07 |
2006-08-30 |
City of Hope |
Cd19-spezifische umgezielte immunzellen
|
US20160279239A1
(en)
|
2011-05-02 |
2016-09-29 |
Immunomedics, Inc. |
Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease
|
US9770517B2
(en)
|
2002-03-01 |
2017-09-26 |
Immunomedics, Inc. |
Anti-Trop-2 antibody-drug conjugates and uses thereof
|
US20080260731A1
(en)
*
|
2002-03-01 |
2008-10-23 |
Bernett Matthew J |
Optimized antibodies that target cd19
|
US7425618B2
(en)
|
2002-06-14 |
2008-09-16 |
Medimmune, Inc. |
Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
|
US9453251B2
(en)
|
2002-10-08 |
2016-09-27 |
Pfenex Inc. |
Expression of mammalian proteins in Pseudomonas fluorescens
|
US7820166B2
(en)
|
2002-10-11 |
2010-10-26 |
Micromet Ag |
Potent T cell modulating molecules
|
US7635472B2
(en)
*
|
2003-05-31 |
2009-12-22 |
Micromet Ag |
Pharmaceutical compositions comprising bispecific anti-cd3, anti-cd19 antibody constructs for the treatment of b-cell related disorders
|
WO2004106380A2
(en)
|
2003-05-31 |
2004-12-09 |
Micromet Ag |
Human-anti-human cd3 binding molecules
|
EP1638514A4
(de)
|
2003-06-06 |
2009-11-18 |
Medimmune Inc |
Verwendung von epha4 und modulator oder epha4 zur diagnose, behandlung und prävention von krebs
|
US7902338B2
(en)
|
2003-07-31 |
2011-03-08 |
Immunomedics, Inc. |
Anti-CD19 antibodies
|
JP4733635B2
(ja)
*
|
2003-07-31 |
2011-07-27 |
イミューノメディクス、インコーポレイテッド |
抗cd19抗体
|
NZ546173A
(en)
*
|
2003-10-16 |
2009-04-30 |
Micromet Ag |
Multispecific deimmunized CD3-binders
|
SI1691833T1
(sl)
*
|
2003-11-28 |
2010-06-30 |
Micromet Ag |
Zmes s polipeptidi
|
US7235641B2
(en)
*
|
2003-12-22 |
2007-06-26 |
Micromet Ag |
Bispecific antibodies
|
US8883160B2
(en)
|
2004-02-13 |
2014-11-11 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
US9550838B2
(en)
|
2004-02-13 |
2017-01-24 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
|
SI1716178T1
(sl)
*
|
2004-02-16 |
2010-11-30 |
Micromet Ag |
Manj imunogene vezne molekule
|
US8603824B2
(en)
|
2004-07-26 |
2013-12-10 |
Pfenex, Inc. |
Process for improved protein expression by strain engineering
|
EP1809326A4
(de)
|
2004-10-27 |
2009-11-04 |
Medimmune Inc |
Modulation von antikörperspezifität mittels anpassung der affinität zu verwandten antigenen
|
US10058621B2
(en)
|
2015-06-25 |
2018-08-28 |
Immunomedics, Inc. |
Combination therapy with anti-HLA-DR antibodies and kinase inhibitors in hematopoietic cancers
|
US20160355591A1
(en)
|
2011-05-02 |
2016-12-08 |
Immunomedics, Inc. |
Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
|
US9707302B2
(en)
|
2013-07-23 |
2017-07-18 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
US8349332B2
(en)
|
2005-04-06 |
2013-01-08 |
Ibc Pharmaceuticals, Inc. |
Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases
|
US8475794B2
(en)
|
2005-04-06 |
2013-07-02 |
Ibc Pharmaceuticals, Inc. |
Combination therapy with anti-CD74 antibodies provides enhanced toxicity to malignancies, Autoimmune disease and other diseases
|
ME02191B
(me)
|
2005-04-18 |
2016-02-20 |
Amgen Res Munich Gmbh |
Protutijela koja neutraliziraju ljudski čimbenik stimuliranja kolonija makrofaga
|
DK1874821T3
(da)
|
2005-04-26 |
2013-07-08 |
Trion Pharma Gmbh |
Kombination af antistoffer med glykokortikoider til behandling af kræft
|
JP5215180B2
(ja)
|
2005-06-20 |
2013-06-19 |
メダレックス インコーポレーティッド |
Cd19抗体およびその使用法
|
AU2006283532B2
(en)
*
|
2005-08-19 |
2012-04-26 |
Abbvie Inc. |
Dual variable domain immunoglobin and uses thereof
|
EP1940881B1
(de)
|
2005-10-11 |
2016-11-30 |
Amgen Research (Munich) GmbH |
Zusammensetzungen mit spezies-kreuzspezifischen antikörpern und verwendungen davon
|
RU2008129080A
(ru)
|
2005-12-16 |
2010-01-27 |
Микромет Аг (De) |
Средства и способы лечения опухолевых заболеваний
|
WO2007071426A1
(en)
|
2005-12-21 |
2007-06-28 |
Micromet Ag |
Pharmaceutical compositions with resistance to soluble cea
|
ATE514081T1
(de)
*
|
2006-03-02 |
2011-07-15 |
Antitope Ltd |
T-zellen-testverfahren
|
PT2383297E
(pt)
|
2006-08-14 |
2013-04-15 |
Xencor Inc |
Anticorpos otimizados que visam cd
|
PT2066349E
(pt)
*
|
2006-09-08 |
2012-07-02 |
Medimmune Llc |
Anticorpos anti-cd19 humanizados e respectiva utilização no tratamento de tumores, transplantação e doenças auto-imunes
|
CN109456410B
(zh)
*
|
2007-04-03 |
2022-01-28 |
安进研发(慕尼黑)股份有限公司 |
跨物种特异性CD3-ε结合结构域
|
WO2008119567A2
(en)
|
2007-04-03 |
2008-10-09 |
Micromet Ag |
Cross-species-specific cd3-epsilon binding domain
|
US20100183615A1
(en)
*
|
2007-04-03 |
2010-07-22 |
Micromet Ag |
Cross-species-specific bispecific binders
|
AU2008245696B2
(en)
|
2007-04-27 |
2013-11-07 |
Pelican Technology Holdings, Inc. |
Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
|
US9580719B2
(en)
|
2007-04-27 |
2017-02-28 |
Pfenex, Inc. |
Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
|
CA3113365A1
(en)
|
2007-07-09 |
2009-01-15 |
Genentech, Inc. |
Prevention of disulfide bond reduction during recombinant production of polypeptides
|
US9096832B2
(en)
*
|
2007-07-31 |
2015-08-04 |
Lifescan, Inc. |
Differentiation of human embryonic stem cells
|
AU2008282218A1
(en)
*
|
2007-07-31 |
2009-02-05 |
Medimmune, Llc |
Multispecific epitope binding proteins and uses thereof
|
SI2211904T1
(sl)
*
|
2007-10-19 |
2016-12-30 |
Seattle Genetics, Inc. |
CD19 vezavna sredstva in njihove uporabe
|
US9308257B2
(en)
|
2007-11-28 |
2016-04-12 |
Medimmune, Llc |
Protein formulation
|
US10981998B2
(en)
|
2008-10-01 |
2021-04-20 |
Amgen Research (Munich) Gmbh |
Cross-species-specific single domain bispecific single chain antibody
|
MX338038B
(es)
*
|
2008-10-01 |
2016-03-30 |
Amgen Res Munich Gmbh |
Anticuerpo de una sola cadena bis-especifico de pscaxcd3, cd19xcd3, c-metxcd3, endosialinaxcd3, epcamxcd3, igf-1rxcd3 o fapalfaxcd3 de especies cruzadas.
|
RS54900B1
(sr)
|
2008-10-01 |
2016-10-31 |
Amgen Res (Munich) Gmbh |
Interspecijski specifično psmaxcd3 bispecifično jednolančano antitelo
|
PT2352763E
(pt)
|
2008-10-01 |
2016-06-02 |
Amgen Res (Munich) Gmbh |
Anticorpos biespecíficos de cadeia única com especificidade para antigénios-alvo com elevado peso molecular
|
PT3330293T
(pt)
|
2008-11-07 |
2019-10-18 |
Amgen Res Munich Gmbh |
Tratamento da leucemia linfoblástica aguda pediátrica com anticorpos biespecíficos contra cd3xcd19
|
MX2011002927A
(es)
|
2008-11-07 |
2011-04-11 |
Micromet Ag |
Nuevo tratamiento de leucemia lifoblastica aguda.
|
EP2389362B1
(de)
|
2009-01-21 |
2019-12-11 |
Oryzon Genomics, S.A. |
Phenylcyclopropylaminderivate und deren medizinische verwendung
|
US9028833B2
(en)
|
2012-12-13 |
2015-05-12 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
|
US9676845B2
(en)
*
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
WO2010151526A1
(en)
|
2009-06-23 |
2010-12-29 |
Alexion Pharmaceuticals, Inc. |
Bispecific antibodies that bind to complement proteins
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
US8859555B2
(en)
|
2009-09-25 |
2014-10-14 |
Oryzon Genomics S.A. |
Lysine Specific Demethylase-1 inhibitors and their use
|
EP2486002B1
(de)
|
2009-10-09 |
2019-03-27 |
Oryzon Genomics, S.A. |
Substituierte heteroaryl- und arylcyclopropylaminacetamide und ihre verwendung
|
PL2493503T5
(pl)
*
|
2009-10-27 |
2021-05-31 |
Amgen Research (Munich) Gmbh |
Schemat dawkowania do podawania dwuswoistego przeciwciała CD19xCD3
|
CA2781682A1
(en)
|
2009-12-04 |
2011-06-09 |
Genentech, Inc. |
Multispecific antibodies, antibody analogs, compositions, and methods
|
WO2011079283A1
(en)
*
|
2009-12-23 |
2011-06-30 |
Bioalliance C.V. |
Anti-epcam antibodies that induce apoptosis of cancer cells and methods using same
|
WO2011106106A2
(en)
|
2010-02-24 |
2011-09-01 |
Oryzon Genomics, S.A. |
Lysine demethylase inhibitors for diseases and disorders associated with hepadnaviridae
|
WO2011106574A2
(en)
|
2010-02-24 |
2011-09-01 |
Oryzon Genomics, S.A. |
Inhibitors for antiviral use
|
TWI653333B
(zh)
|
2010-04-01 |
2019-03-11 |
安進研究(慕尼黑)有限責任公司 |
跨物種專一性之PSMAxCD3雙專一性單鏈抗體
|
PL2560947T3
(pl)
|
2010-04-19 |
2017-04-28 |
Oryzon Genomics, S.A. |
Inhibitory demetylazy specyficznej dla lizyny i ich zastosowanie
|
JP2013533732A
(ja)
|
2010-05-03 |
2013-08-29 |
ジェネンテック, インコーポレイテッド |
腫瘍の診断と治療のための組成物と方法
|
JP5636091B2
(ja)
|
2010-05-05 |
2014-12-03 |
ウニベルジテート バイロイト |
癌治療に用いるためのコンブレタスタチン類似体
|
CN102250245B
(zh)
*
|
2010-05-27 |
2014-05-14 |
四川大学 |
抗b细胞淋巴瘤的双特异性抗体及其用途
|
CA2806006A1
(en)
|
2010-07-28 |
2012-02-02 |
Medizinische Universitaet Wien |
Vinylogous chalcone derivatives and their medical use
|
EP2598480B1
(de)
|
2010-07-29 |
2019-04-24 |
Oryzon Genomics, S.A. |
Cyclopropylaminderivate als lsd1-hemmer
|
DK3029066T3
(da)
|
2010-07-29 |
2019-05-20 |
Xencor Inc |
Antistoffer med modificerede isoelektriske punkter
|
CN104892525A
(zh)
|
2010-07-29 |
2015-09-09 |
奥瑞泽恩基因组学股份有限公司 |
Lsd1的基于芳基环丙胺的脱甲基酶抑制剂及其医疗用途
|
US9061966B2
(en)
|
2010-10-08 |
2015-06-23 |
Oryzon Genomics S.A. |
Cyclopropylamine inhibitors of oxidases
|
SI2632954T2
(sl)
|
2010-10-27 |
2021-11-30 |
Amgen Research (Munich) Gmbh |
Sredstva in postopki za zdravljenje dlbcl
|
FI2637670T4
(fi)
|
2010-11-10 |
2024-03-19 |
Amgen Research Munich Gmbh |
Cd3-spesifisten sitoutumisdomeenien aiheuttamien haittavaikutusten estäminen
|
EP2640750A1
(de)
|
2010-11-16 |
2013-09-25 |
Boehringer Ingelheim International GmbH |
Mittel und verfahren zur behandlung von mit bcma-expression korrelierenden erkrankungen
|
WO2012072713A2
(en)
|
2010-11-30 |
2012-06-07 |
Oryzon Genomics, S.A. |
Lysine demethylase inhibitors for diseases and disorders associated with flaviviridae
|
EP2712315B1
(de)
|
2011-02-08 |
2021-11-24 |
Oryzon Genomics, S.A. |
Lysindemethylase-hemmer für myeloproliferative erkrankungen
|
EP2673297A2
(de)
|
2011-02-11 |
2013-12-18 |
Zyngenia, Inc. |
Monovalente und multivalente multispezifische komplexe und verwendungen davon
|
JP6276175B2
(ja)
|
2011-04-28 |
2018-02-07 |
アムジェン リサーチ (ミュニック) ゲゼルシャフト ミット ベシュレンクテル ハフツング |
潜在的有害作用リスクのある患者にCD19xCD3二特異性抗体を投与するための投薬レジメン
|
MY173899A
(en)
|
2011-05-21 |
2020-02-26 |
Macrogenics Inc |
Cd3-binding molecules capable of binding to human and non-human cd3
|
AU2012258637B2
(en)
|
2011-05-24 |
2017-07-20 |
Zyngenia, Inc. |
Multivalent and monovalent multispecific complexes and their uses
|
KR102111171B1
(ko)
|
2011-06-10 |
2020-05-14 |
메디뮨 엘엘씨 |
항슈도모나스 psl 결합 분자 및 그의 용도
|
KR20140064873A
(ko)
*
|
2011-08-16 |
2014-05-28 |
모르포시스 아게 |
항-cd19 항체 및 질소 머스타드를 사용한 조합 요법
|
DE102012016127A1
(de)
|
2011-08-31 |
2013-02-28 |
Daniel Elias |
Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels
|
AU2012311492A1
(en)
|
2011-09-23 |
2014-03-06 |
Amgen Research (Munich) Gmbh |
Bispecific binding molecules for 5T4 and CD3
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
US9469597B2
(en)
|
2011-10-20 |
2016-10-18 |
Oryzon Genomics S.A. |
(Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors
|
EP2768805B1
(de)
|
2011-10-20 |
2020-03-25 |
Oryzon Genomics, S.A. |
(hetero)aryl cyclopropylamin verbindungen als lsd1 hemmer
|
CN104136042B
(zh)
|
2011-11-07 |
2017-08-18 |
米迪缪尼有限公司 |
使用抗假单胞菌Psl和PcrV结合分子的联合治疗
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
WO2013085893A1
(en)
|
2011-12-05 |
2013-06-13 |
Immunomedics, Inc. |
Therapeutic use of anti-cd22 antibodies for inducing trogocytosis
|
US9757458B2
(en)
|
2011-12-05 |
2017-09-12 |
Immunomedics, Inc. |
Crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in hematopoietic cancer cells
|
BR112014019116B1
(pt)
*
|
2012-02-03 |
2024-01-23 |
F.Hoffmann-La Roche Ag |
Kit, moléculas de anticorpo e uso de uma molécula de anticorpo
|
WO2013126712A1
(en)
|
2012-02-22 |
2013-08-29 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for generating a persisting population of t cells useful for the treatment of cancer
|
GB201203442D0
(en)
|
2012-02-28 |
2012-04-11 |
Univ Birmingham |
Immunotherapeutic molecules and uses
|
US20150037334A1
(en)
|
2012-03-01 |
2015-02-05 |
Amgen Research (Munich) Gmbh |
Long life polypeptide binding molecules
|
CN103382223B
(zh)
|
2012-04-01 |
2015-06-10 |
上海益杰生物技术有限公司 |
针对表皮生长因子受体隐蔽表位和t细胞抗原的多功能抗体多肽
|
US20140004121A1
(en)
|
2012-06-27 |
2014-01-02 |
Amgen Inc. |
Anti-mesothelin binding proteins
|
EP2872526B1
(de)
|
2012-07-13 |
2020-04-01 |
The Trustees of the University of Pennsylvania |
Verstärkung der aktivität von car-t-zellen durch miteinführung eines bispezifischen antikörpers
|
CN109513003A
(zh)
|
2012-08-14 |
2019-03-26 |
Ibc药品公司 |
用于治疗疾病的t-细胞重定向双特异性抗体
|
US9682143B2
(en)
|
2012-08-14 |
2017-06-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
US10131712B2
(en)
|
2012-08-14 |
2018-11-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy with T-cell redirecting bispecific antibodies and checkpoint inhibitors
|
US20150231241A1
(en)
|
2012-08-14 |
2015-08-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
US9382329B2
(en)
|
2012-08-14 |
2016-07-05 |
Ibc Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to Trop-2 expressing cells
|
JOP20200236A1
(ar)
|
2012-09-21 |
2017-06-16 |
Regeneron Pharma |
الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
|
AR093297A1
(es)
|
2012-10-31 |
2015-05-27 |
Amgen Res (Munich) Gmbh |
Formulacion liquida que comprende un compuesto neutralizante de gm-csf
|
US9833410B2
(en)
|
2012-10-31 |
2017-12-05 |
Takeda Gmbh |
Lyophilized formulation comprising GM-CSF neutralizing compound
|
CN103833852A
(zh)
*
|
2012-11-23 |
2014-06-04 |
上海市肿瘤研究所 |
针对磷脂酰肌醇蛋白多糖-3和t细胞抗原的双特异性抗体
|
US10137196B2
(en)
|
2012-12-13 |
2018-11-27 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
|
ES2819573T3
(es)
|
2012-12-13 |
2021-04-16 |
Immunomedics Inc |
Método para producir inmunoconjugados de anticuerpo-SN-38 con un enlazador CL2A
|
US10206918B2
(en)
|
2012-12-13 |
2019-02-19 |
Immunomedics, Inc. |
Efficacy of anti-HLA-DR antiboddy drug conjugate IMMU-140 (hL243-CL2A-SN-38) in HLA-DR positive cancers
|
US9492566B2
(en)
|
2012-12-13 |
2016-11-15 |
Immunomedics, Inc. |
Antibody-drug conjugates and uses thereof
|
US10413539B2
(en)
|
2012-12-13 |
2019-09-17 |
Immunomedics, Inc. |
Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132)
|
US10744129B2
(en)
|
2012-12-13 |
2020-08-18 |
Immunomedics, Inc. |
Therapy of small-cell lung cancer (SCLC) with a topoisomerase-I inhibiting antibody-drug conjugate (ADC) targeting Trop-2
|
US9931417B2
(en)
|
2012-12-13 |
2018-04-03 |
Immunomedics, Inc. |
Antibody-SN-38 immunoconjugates with a CL2A linker
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
DK2943511T3
(da)
|
2013-01-14 |
2019-10-21 |
Xencor Inc |
Nye heterodimeriske proteiner
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
US9738722B2
(en)
|
2013-01-15 |
2017-08-22 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
CN103965359B
(zh)
*
|
2013-01-24 |
2016-08-03 |
上海市肿瘤研究所 |
抗上皮细胞粘附分子和t细胞抗原的双特异性抗体
|
EP2948478B1
(de)
|
2013-01-25 |
2019-04-03 |
Amgen Inc. |
Antikörper gegen cdh19 für melanome
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
US9486475B2
(en)
|
2013-02-08 |
2016-11-08 |
Amgen Research (Munich) Gmbh |
PPS for the prevention of potential adverse effects caused by CD3 specific binding domains
|
JO3529B1
(ar)
|
2013-02-08 |
2020-07-05 |
Amgen Res Munich Gmbh |
مضاد التصاق خلايا الدم البيض من أجل التخفيف من الاثار السلبية الممكنة الناتجة عن مجالات ارتباط cd3- المحدد
|
JP2016512199A
(ja)
|
2013-03-05 |
2016-04-25 |
ベイラー カレッジ オブ メディスンBaylor College Of Medicine |
腫瘍溶解性ウイルス
|
JP6420776B2
(ja)
|
2013-03-05 |
2018-11-07 |
ベイラー カレッジ オブ メディスンBaylor College Of Medicine |
免疫療法のためのエンゲージャー細胞
|
US9802995B2
(en)
*
|
2013-03-15 |
2017-10-31 |
Memorial Sloan-Kettering Cancer Center |
Antibody multimerization technologies
|
US9505849B2
(en)
|
2013-03-15 |
2016-11-29 |
Amgen Research (Munich) Gmbh |
Antibody constructs for influenza M2 and CD3
|
US9561291B2
(en)
*
|
2013-03-15 |
2017-02-07 |
Imre Kovesdi |
Methods of targeting T-cells to tumors
|
US20140302037A1
(en)
*
|
2013-03-15 |
2014-10-09 |
Amgen Inc. |
BISPECIFIC-Fc MOLECULES
|
EP2968541A4
(de)
|
2013-03-15 |
2017-02-08 |
Zyngenia, Inc. |
Multivalente und monovalente multispezifische komplexe und deren verwendungen
|
SI2970449T1
(sl)
|
2013-03-15 |
2019-11-29 |
Amgen Res Munich Gmbh |
Enoverižne vezavne molekule, ki vsebujejo N-terminalni ABP
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
CA3093606A1
(en)
|
2013-03-15 |
2014-09-18 |
Xencor, Inc. |
Heterodimeric proteins for induction of t cells
|
AR095374A1
(es)
|
2013-03-15 |
2015-10-14 |
Amgen Res (Munich) Gmbh |
Moléculas de unión para bcma y cd3
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
CN107460201A
(zh)
*
|
2013-05-08 |
2017-12-12 |
科济生物医药(上海)有限公司 |
编码gpc‑3嵌合抗原受体蛋白的核酸及表达gpc‑3嵌合抗原受体蛋白的t淋巴细胞
|
WO2014180577A1
(en)
|
2013-05-10 |
2014-11-13 |
Numab Ag |
Bispecific constructs and their use in the treatment of various diseases
|
CA2917919C
(en)
*
|
2013-07-09 |
2019-07-02 |
Duke University |
Certain improved human bispecific egfrviii antibody engaging molecules
|
US11253606B2
(en)
|
2013-07-23 |
2022-02-22 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
CN104342453A
(zh)
*
|
2013-08-06 |
2015-02-11 |
深圳先进技术研究院 |
含基因工程抗体基因表达盒的微环dna重组母质粒、含该表达盒的微环dna及应用
|
EP3039039B1
(de)
|
2013-08-30 |
2021-03-10 |
Takeda GmbH |
Gm-csf-neutralisierende antikörper zur verwendung bei der behandlung von rheumatoider arthritis und als analgetika
|
TWI688401B
(zh)
|
2013-09-13 |
2020-03-21 |
美商安進公司 |
用於治療骨髓性白血病的表觀遺傳因子與靶向cd33及cd3之雙特異性化合物的組合
|
CA2925393C
(en)
|
2013-10-11 |
2023-03-07 |
Dimiter Dimitrov |
Tem8 antibodies and their use
|
CN104623637A
(zh)
|
2013-11-07 |
2015-05-20 |
健能隆医药技术(上海)有限公司 |
Il-22二聚体在制备静脉注射药物中的应用
|
WO2015103549A1
(en)
|
2014-01-03 |
2015-07-09 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
CA2937236C
(en)
|
2014-02-21 |
2023-03-07 |
Ibc Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to trop-2 expressing cells
|
CA2935748A1
(en)
|
2014-02-25 |
2015-09-03 |
Immunomedics, Inc. |
Humanized rfb4 anti-cd22 antibody
|
TWI754319B
(zh)
|
2014-03-19 |
2022-02-01 |
美商再生元醫藥公司 |
用於腫瘤治療之方法及抗體組成物
|
KR20230022270A
(ko)
|
2014-03-28 |
2023-02-14 |
젠코어 인코포레이티드 |
Cd38 및 cd3에 결합하는 이중특이적 항체
|
RU2577226C2
(ru)
*
|
2014-04-10 |
2016-03-10 |
Общество с ограниченной ответственностью, "Международный биотехнологический центр "Генериум" ("МБЦ "Генериум") |
Способ получения биспецифических антител против cd3*cd19 формата флексибоди в клетках млекопитающих
|
RU2568910C2
(ru)
*
|
2014-04-18 |
2015-11-20 |
Общество с ограниченной ответственностью "Международный биотехнологический центр "Генериум" ("МБЦ "Генериум") |
Фармацевтические композиции на основе флексибоди против cd3*cd19 для лечения в-клеточных заболеваний
|
CN105017422A
(zh)
*
|
2014-04-30 |
2015-11-04 |
山东百因制药技术有限公司 |
一种抗cd3/抗cd19双特异性抗体及其应用
|
EA201691883A1
(ru)
|
2014-05-07 |
2017-05-31 |
Такеда Гмбх |
Жидкая композиция, содержащая соединение, нейтрализующее gm-csf
|
WO2015172341A1
(zh)
*
|
2014-05-14 |
2015-11-19 |
上海市肿瘤研究所 |
针对磷脂酰肌醇蛋白多糖-3和t细胞抗原的双特异性抗体
|
EP2947460A1
(de)
|
2014-05-22 |
2015-11-25 |
Medizinische Universität Wien |
Personalisierte Therapie von Entzündungen um Zusammenhang mit Krebs mithilfe von Verfahren zur Bestimmung der Empfänglichkeit auf die Behandlung mit EGFR-Hemmern/-Antagonisten
|
EP4303585A3
(de)
|
2014-05-30 |
2024-01-24 |
Amgen Research (Munich) GmbH |
Risikostratifizierung von patienten mit akuter lymphatischer b-vorläufer-leukämie
|
BR112016030740A2
(pt)
|
2014-07-01 |
2018-02-20 |
Pfizer Inc. |
diacorpos heterodiméricos biespecíficos e seus usos
|
CN107108738A
(zh)
|
2014-07-25 |
2017-08-29 |
西托姆克斯治疗公司 |
抗cd3抗体、可活化抗cd3抗体、多特异性抗cd3抗体、多特异性可活化抗cd3抗体及其使用方法
|
TW201609812A
(zh)
|
2014-07-31 |
2016-03-16 |
安美基研究(慕尼黑)公司 |
最佳化之跨物種特異性雙特異性單鏈抗體構築體
|
UY36245A
(es)
|
2014-07-31 |
2016-01-29 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
CA2952540C
(en)
|
2014-07-31 |
2022-06-21 |
Amgen Research (Munich) Gmbh |
Bispecific single chain antibody construct with enhanced tissue distribution
|
EP3186237A1
(de)
|
2014-08-28 |
2017-07-05 |
Medizinische Universität Wien |
Heteroaromatische chalconderivate und deren medizinische verwendung
|
US10160795B2
(en)
|
2014-11-14 |
2018-12-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to Ebola virus glycoprotein and their use
|
CA2967820A1
(en)
|
2014-11-17 |
2016-05-26 |
Regeneron Pharmaceuticals, Inc. |
Methods for tumor treatment using cd3xcd20 bispecific antibody
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
IL252480B2
(en)
|
2014-11-26 |
2023-12-01 |
Xencor Inc |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
AU2015353416C1
(en)
|
2014-11-26 |
2022-01-27 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and CD38
|
EP3029067A1
(de)
|
2014-12-01 |
2016-06-08 |
Deutsches Krebsforschungszentrum |
Verwendung von blockierenden Reagenzien zur Verringerung von unspezifischer T-Zellenaktivierung
|
WO2016094834A2
(en)
|
2014-12-12 |
2016-06-16 |
Alexion Pharmaceuticals, Inc. |
A method for treating a complement mediated disorder caused by an infectious agent in a patient
|
US10428155B2
(en)
|
2014-12-22 |
2019-10-01 |
Xencor, Inc. |
Trispecific antibodies
|
NZ734803A
(en)
|
2015-01-23 |
2023-03-31 |
Sanofi Sa |
Anti-cd3 antibodies, anti-cd123 antibodies and bispecific antibodies specifically binding to cd3 and/or cd123
|
EP3262064A1
(de)
|
2015-02-23 |
2018-01-03 |
Seagull Therapeutics SAS |
Nichtnatürliche semaphorine 3 und deren medizinische verwendung
|
WO2016135140A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
4-aminoquinazoline derivatives as mth1 inhibitors for the therapy of cancer
|
WO2016135137A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Substituted 4-(phenylamino)quinoline derivatives as mth1 inhibitors for the therapy of cancer
|
WO2016135138A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Oxoquinoline derivatives as mth1 inhibitors for the therapy of cancer
|
WO2016135139A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
2,3-dihydrocyclopenta[b]quinoline derivatives as mth1 inhibitors for the therapy of cancer
|
KR20170140180A
(ko)
|
2015-02-24 |
2017-12-20 |
더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 |
중동 호흡기 증후군 코로나 바이러스 면역원, 항체 및 그 용도
|
KR20210096326A
(ko)
|
2015-02-24 |
2021-08-04 |
바이오아트라, 인코퍼레이티드 |
조건부 활성 생체 단백질
|
WO2016141387A1
(en)
|
2015-03-05 |
2016-09-09 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
EP3064507A1
(de)
|
2015-03-06 |
2016-09-07 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Fusionsproteine mit einem bindenden Protein und einem Interleukin-15-Polypeptid mit reduzierter Affinität für IL15ra und therapeutische Verwendungen davon
|
US10562960B2
(en)
|
2015-03-20 |
2020-02-18 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to gp120 and their use
|
US20180084766A1
(en)
*
|
2015-04-07 |
2018-03-29 |
The Children's Medical Center Corporation |
Methods and compositions relating to an embryonic stem cell-based tumor model
|
ES2945313T3
(es)
|
2015-04-17 |
2023-06-30 |
Amgen Res Munich Gmbh |
Construcciones de anticuerpos biespecificos para CDH3 y CD3
|
WO2016170102A1
(en)
|
2015-04-22 |
2016-10-27 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Combination of an antiandrogen with a vitamin k antagonist or with a gamma -glutamyl carboxylase inhibitor for the therapy of androgen receptor positive cancer
|
AU2016252771B2
(en)
|
2015-04-22 |
2021-12-16 |
Immunomedics, Inc. |
Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells
|
RS59376B1
(sr)
|
2015-05-13 |
2019-11-29 |
Ablynx Nv |
Polipeptidi koji regrutuju t-ćelije na bazi tcr-alfa/beta reaktivnosti
|
CN107847559B
(zh)
|
2015-05-13 |
2022-07-01 |
埃博灵克斯股份有限公司 |
基于cd3反应性的t细胞募集多肽
|
KR102537102B1
(ko)
|
2015-05-29 |
2023-05-25 |
엠피베나 테라퓨틱스, 인크. |
이중특이적 cd33 및 cd3 결합 단백질을 사용하는 방법
|
WO2016196975A1
(en)
|
2015-06-03 |
2016-12-08 |
The United States Of America, As Represented By The Secretary Department Of Health & Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
US10195175B2
(en)
|
2015-06-25 |
2019-02-05 |
Immunomedics, Inc. |
Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
|
CN106349391A
(zh)
*
|
2015-07-17 |
2017-01-25 |
中国科学院深圳先进技术研究院 |
Hbv特异性双靶向抗体及其制备方法和应用、含该双靶向抗体表达盒的微环dna及应用
|
TWI793062B
(zh)
|
2015-07-31 |
2023-02-21 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
JO3620B1
(ar)
|
2015-08-05 |
2020-08-27 |
Amgen Res Munich Gmbh |
مثبطات نقطة فحص مناعية للاستخدام في علاج سرطانات محمولة عبر الدم
|
US11713358B2
(en)
|
2015-08-28 |
2023-08-01 |
Amunix Pharmaceuticals, Inc. |
Chimeric polypeptide assembly and methods of making and using the same
|
WO2017044811A1
(en)
|
2015-09-11 |
2017-03-16 |
Bruce Andrien |
Recombinant glycosylated eculizumab and eculizumab variants
|
MA44909A
(fr)
|
2015-09-15 |
2018-07-25 |
Acerta Pharma Bv |
Association thérapeutique d'un inhibiteur du cd19 et d'un inhibiteur de la btk
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
EP3356407B1
(de)
|
2015-10-02 |
2021-11-03 |
F. Hoffmann-La Roche AG |
Bispezifische anti-cd19xcd3-t-zell-aktivierende antigenbindende moleküle
|
CA2997809A1
(en)
|
2015-10-07 |
2017-04-13 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Il-7r-alpha specific antibodies for treating acute lymphoblastic leukemia
|
EP3359566A1
(de)
|
2015-10-07 |
2018-08-15 |
Alexion Pharmaceuticals, Inc. |
Verfahren zur behandlung altersbedingter makuladegeneration bei einem patienten
|
JP7064769B2
(ja)
|
2015-11-02 |
2022-05-11 |
バイオアトラ、エルエルシー |
条件的活性型ポリペプチド
|
CA3003878A1
(en)
|
2015-11-03 |
2017-05-11 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 gp41 and their use
|
CN105296421B
(zh)
*
|
2015-11-24 |
2019-01-29 |
高岱清 |
一种双特异性抗体活化的t细胞及制备方法与应用
|
RU2651776C2
(ru)
*
|
2015-12-01 |
2018-04-23 |
Общество с ограниченной ответственностью "Международный биотехнологический центр "Генериум" ("МБЦ "Генериум") |
Биспецифические антитела против cd3*cd19
|
US11623957B2
(en)
|
2015-12-07 |
2023-04-11 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and PSMA
|
CA3004630A1
(en)
|
2015-12-09 |
2017-06-15 |
Medizinische Universitat Wien |
Monomaleimide-functionalized platinum compounds for cancer therapy
|
TW202208440A
(zh)
|
2015-12-14 |
2022-03-01 |
美商宏觀基因股份有限公司 |
對於pd-1和ctla-4具有免疫反應性的雙特異性分子及其使用方法
|
EA039859B1
(ru)
|
2016-02-03 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
AU2017216237B2
(en)
|
2016-02-03 |
2024-04-04 |
Amgen Research (Munich) Gmbh |
PSMA and CD3 bispecific T cell engaging antibody constructs
|
BR112018015715A2
(pt)
|
2016-02-03 |
2019-02-05 |
Amgen Inc |
construtos de anticorpo de engate de célula t biespecífica bcma e cd3
|
US20170224837A1
(en)
|
2016-02-10 |
2017-08-10 |
Immunomedics, Inc. |
Combination of abcg2 inhibitors with sacituzumab govitecan (immu-132) overcomes resistance to sn-38 in trop-2 expressing cancers
|
KR20180134860A
(ko)
|
2016-02-15 |
2018-12-19 |
체엠엠 - 포르슝스첸트룸 퓨어 몰레쿨라레 메디친 게엠베하 |
암의 치료를 위한 taf1 억제제
|
EP3216458A1
(de)
|
2016-03-07 |
2017-09-13 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Modifizierter vaskulärer endothelialen wachstumsfaktor a (vegf-a) und dessen medizinische verwendung
|
KR102584300B1
(ko)
|
2016-03-29 |
2023-10-05 |
유니버시티 오브 써던 캘리포니아 |
암을 표적하는 키메라 항원 수용체
|
WO2017167350A1
(en)
*
|
2016-03-30 |
2017-10-05 |
Horst Lindhofer |
Multispecific antibodies for use in the treatment of a neoplasm of the urinary tract
|
AU2017249698B2
(en)
*
|
2016-04-13 |
2023-03-09 |
Vivia Biotech, S.L |
Ex vivo bite-activated T cells
|
ES2930351T3
(es)
|
2016-04-15 |
2022-12-09 |
Evive Biotechnology Shanghai Ltd |
Un dímero de IL-22 para su uso en el tratamiento de enterocolitis necrosante
|
JOP20170091B1
(ar)
|
2016-04-19 |
2021-08-17 |
Amgen Res Munich Gmbh |
إعطاء تركيبة ثنائية النوعية ترتبط بـ cd33 وcd3 للاستخدام في طريقة لعلاج اللوكيميا النخاعية
|
CA3016917A1
(en)
|
2016-04-27 |
2017-11-02 |
Immunomedics, Inc. |
Efficacy of anti-trop-2-sn-38 antibody drug conjugates for therapy of tumors relapsed/refractory to checkpoint inhibitors
|
WO2017192589A1
(en)
|
2016-05-02 |
2017-11-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to influenza ha and their use and identification
|
CN105906720A
(zh)
*
|
2016-05-16 |
2016-08-31 |
武汉汉密顿生物科技股份有限公司 |
靶向性嵌合抗原受体修饰的免疫细胞及其制备方法和应用
|
RU2022104399A
(ru)
|
2016-06-14 |
2022-05-05 |
Ксенкор, Инк. |
Биспецифические антитела-ингибиторы контрольных точек
|
US10669338B2
(en)
|
2016-06-17 |
2020-06-02 |
Immunomedics, Inc. |
Anti-PD-1 checkpoint inhibitor antibodies that block binding of PD-L1 to PD-1
|
MX2018016265A
(es)
|
2016-06-28 |
2019-07-04 |
Xencor Inc |
Anticuerpos heterodimericos que se unen al receptor 2 de somatostatina.
|
WO2018006005A1
(en)
|
2016-06-30 |
2018-01-04 |
Oncorus, Inc. |
Pseudotyped oncolytic viral delivery of therapeutic polypeptides
|
TWI790206B
(zh)
|
2016-07-18 |
2023-01-21 |
法商賽諾菲公司 |
特異性結合至cd3和cd123的雙特異性抗體樣結合蛋白
|
JP6994018B2
(ja)
|
2016-07-26 |
2022-01-14 |
バイオマリン ファーマシューティカル インコーポレイテッド |
新規アデノ随伴ウイルスキャプシドタンパク質
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
WO2018049248A1
(en)
|
2016-09-09 |
2018-03-15 |
Icellhealth Consulting Llc |
Oncolytic virus equipped with bispecific engager molecules
|
WO2018057915A1
(en)
|
2016-09-23 |
2018-03-29 |
The Regents Of The University Of Michigan |
Engineered lymphocytes
|
PE20191034A1
(es)
|
2016-10-14 |
2019-08-05 |
Xencor Inc |
Proteinas de fusion heterodimericas biespecificas que contienen proteinas de fusion fc il-15/il-15r y fragmentos de anticuerpo pd-1
|
WO2018075758A1
(en)
|
2016-10-19 |
2018-04-26 |
Alexion Pharmaceuticals, Inc. |
A method of quantitating unbound c5 in a sample
|
CN110225755A
(zh)
|
2016-11-14 |
2019-09-10 |
分子医学研究中心责任有限公司 |
Brd4抑制剂和抗叶酸剂的组合用于治疗癌症
|
MX2019005696A
(es)
|
2016-11-16 |
2019-08-14 |
Ablynx Nv |
Polipeptidos de reclutamiento de celulas t capaces de unir cd123 y tcr alfa/beta.
|
EP3556772A4
(de)
*
|
2016-12-13 |
2020-09-09 |
Carsgen Therapeutics Ltd |
Humanisierter anti-cd19-antikörper und gegen cd19 gerichtete immuneffektorzelle
|
CN108264557B
(zh)
*
|
2016-12-30 |
2021-08-24 |
惠和生物技术(上海)有限公司 |
一种结合cd3和t细胞负共刺激分子的双功能分子及其应用
|
CN108264566B
(zh)
*
|
2016-12-30 |
2021-05-14 |
惠和生物技术(上海)有限公司 |
一种融合抗cd3抗体结构域和t细胞正共刺激分子配体的双特异性分子及其应用
|
JOP20190189A1
(ar)
|
2017-02-02 |
2019-08-01 |
Amgen Res Munich Gmbh |
تركيبة صيدلانية ذات درجة حموضة منخفضة تتضمن بنيات جسم مضاد يستهدف الخلية t
|
SG11201907299XA
(en)
|
2017-02-08 |
2019-09-27 |
Dragonfly Therapeutics Inc |
Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
|
US11021535B2
(en)
|
2017-02-10 |
2021-06-01 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
|
WO2018152496A1
(en)
|
2017-02-17 |
2018-08-23 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Compositions and methods for the diagnosis and treatment of zika virus infection
|
DK3582806T3
(da)
|
2017-02-20 |
2023-09-11 |
Dragonfly Therapeutics Inc |
Proteiner, der binder her2, nkg2d og cd16
|
SG11201907753TA
(en)
|
2017-02-24 |
2019-09-27 |
Macrogenics Inc |
Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof
|
CA3050332A1
(en)
|
2017-03-27 |
2018-10-04 |
Immunomedics, Inc. |
Treatment of trop-2 expressing triple negative breast cancer with sacituzumab govitecan and a rad51 inhibitor
|
CN108659112B
(zh)
*
|
2017-03-30 |
2021-01-26 |
上海市同济医院 |
一种非对称双特异性抗体
|
CN110352201A
(zh)
|
2017-04-03 |
2019-10-18 |
免疫医疗公司 |
用于癌症疗法的抗体药物缀合物的皮下施用
|
EP3615569A1
(de)
|
2017-04-25 |
2020-03-04 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Antikörper und verfahren zur diagnose und behandlung von epstein-barr-virus-infektionen
|
CA3059820A1
(en)
|
2017-04-26 |
2018-11-01 |
Eureka Therapeutics, Inc. |
Constructs specifically recognizing glypican 3 and uses thereof
|
EP3618864A1
(de)
|
2017-05-05 |
2020-03-11 |
Amgen Inc. |
Pharmazeutische zusammensetzung mit bispezifischen antikörperkonstrukten zur verbesserten aufbewahrung und verabreichung
|
WO2018224441A1
(en)
|
2017-06-05 |
2018-12-13 |
Numab Innovation Ag |
Novel anti-cd3 antibodies
|
CA3068049A1
(en)
*
|
2017-06-25 |
2019-01-03 |
Systimmune, Inc. |
Multi-specific antibodies and methods of making and using thereof
|
CN111132733A
(zh)
|
2017-06-30 |
2020-05-08 |
Xencor股份有限公司 |
含有IL-15/IL-15Rα和抗原结合结构域的靶向异源二聚体Fc融合蛋白
|
CN111094334A
(zh)
|
2017-07-19 |
2020-05-01 |
美国卫生与公众服务部 |
用于诊断和治疗乙肝病毒感染的抗体和方法
|
MA56289B1
(fr)
|
2017-08-03 |
2022-04-29 |
Amgen Inc |
Mutéines d'interleukine-21 et méthodes de traitement
|
TWI731264B
(zh)
|
2017-09-08 |
2021-06-21 |
美商安進公司 |
Kras g12c抑制劑以及其使用方法
|
IL302614A
(en)
|
2017-09-08 |
2023-07-01 |
Maverick Therapeutics Inc |
Binding proteins are activated under limited conditions
|
PL3681483T3
(pl)
|
2017-09-15 |
2022-09-26 |
Amgen Inc. |
Sposób liofilizowanej farmaceutycznej formulacji białka terapeutycznego
|
US11912754B2
(en)
|
2017-10-12 |
2024-02-27 |
Immunowake Inc. |
VEGFR-antibody light chain fusion protein
|
WO2019075366A1
(en)
|
2017-10-13 |
2019-04-18 |
Merck Sharp & Dohme Corp. |
COMPOSITIONS AND METHODS FOR TREATING DIFFUSED LYMPHOMA WITH LARGE B CELLS
|
CA3078911A1
(en)
|
2017-10-14 |
2019-04-18 |
Cytomx Therapeutics, Inc. |
Antibodies, activatable antibodies, bispecific antibodies, and bispecific activatable antibodies and methods of use thereof
|
CN107739410B
(zh)
*
|
2017-10-18 |
2021-07-30 |
南京鼓楼医院 |
CD3单链抗体-iRGD融合蛋白、制备及其作为抗肿瘤药物的应用
|
KR20200074201A
(ko)
|
2017-11-02 |
2020-06-24 |
바이엘 악티엔게젤샤프트 |
Alk-1 및 bmpr-2에 결합하는 이중특이적 항체
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
JP2021502100A
(ja)
|
2017-11-08 |
2021-01-28 |
ゼンコア インコーポレイテッド |
新規抗pd−1配列を用いた二重特異性および単一特異性抗体
|
CA3082507A1
(en)
|
2017-12-11 |
2019-06-20 |
Amgen Inc. |
Continuous manufacturing process for bispecific antibody products
|
KR20200098590A
(ko)
|
2017-12-12 |
2020-08-20 |
마크로제닉스, 인크. |
이중특이적 cd16-결합 분자 및 질환 치료에서의 그것의 용도
|
MX2020006322A
(es)
|
2017-12-19 |
2020-09-18 |
Xencor Inc |
Proteinas de fusion il-2 fc modificadas.
|
EP3731850A4
(de)
|
2017-12-29 |
2021-12-01 |
Oncorus, Inc. |
Onkolytische virale verabreichung von therapeutischen polypeptiden
|
TW201940518A
(zh)
|
2017-12-29 |
2019-10-16 |
美商安進公司 |
針對muc17和cd3之雙特異性抗體構建體
|
WO2019136029A1
(en)
|
2018-01-02 |
2019-07-11 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to ebola virus glycoprotein and their use
|
CN107987169B
(zh)
*
|
2018-01-05 |
2021-10-08 |
阿思科力(苏州)生物科技有限公司 |
一种以ROBO1为靶点的双特异性抗体scFv及其制备和应用
|
CA3087273A1
(en)
|
2018-01-12 |
2019-07-18 |
Amgen Inc. |
Anti-pd-1 antibodies and methods of treatment
|
MX2020008336A
(es)
|
2018-02-08 |
2020-09-21 |
Dragonfly Therapeutics Inc |
Dominios variables de anticuerpos que se dirigen al receptor nkg2d.
|
AU2019222666A1
(en)
|
2018-02-15 |
2020-09-03 |
Macrogenics, Inc. |
Variant CD3-binding domains and their use in combination therapies for the treatment of disease
|
US11760790B2
(en)
|
2018-02-21 |
2023-09-19 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to HIV-1 Env and their use
|
EP3759146A1
(de)
|
2018-03-02 |
2021-01-06 |
CDR-Life AG |
Trispezifische antigenbindende proteine
|
CN111867598A
(zh)
*
|
2018-03-13 |
2020-10-30 |
国立大学法人大阪大学 |
肿瘤免疫赋活剂
|
US20190284288A1
(en)
|
2018-03-19 |
2019-09-19 |
The Regents Of The University Of Michigan |
Compositions and methods for t-cell and cytokine activation
|
WO2019195623A2
(en)
|
2018-04-04 |
2019-10-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
JP2021520829A
(ja)
|
2018-04-18 |
2021-08-26 |
ゼンコア インコーポレイテッド |
IL−15/IL−15RA Fc融合タンパク質およびTIM−3抗原結合ドメインを含む、TIM−3標的化ヘテロ二量体融合タンパク質
|
SG11202010163QA
(en)
|
2018-04-18 |
2020-11-27 |
Xencor Inc |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
WO2019207051A1
(en)
|
2018-04-25 |
2019-10-31 |
Università Degli Studi Di Torino |
Medical use of combinations of non-natural semaphorins 3 and antimetabolites
|
US20210171610A1
(en)
|
2018-05-02 |
2021-06-10 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Antibodies and methods for the diagnosis, prevention, and treatment of epstein barr virus infection
|
US11739345B2
(en)
|
2018-05-09 |
2023-08-29 |
Biomarin Pharmaceutical Inc. |
Methods of treating phenylketonuria
|
TW202005978A
(zh)
|
2018-05-14 |
2020-02-01 |
美商拜奧馬林製藥公司 |
新穎肝靶向腺相關病毒載體
|
US20220403001A1
(en)
|
2018-06-12 |
2022-12-22 |
Obsidian Therapeutics, Inc. |
Pde5 derived regulatory constructs and methods of use in immunotherapy
|
WO2020010079A2
(en)
|
2018-07-02 |
2020-01-09 |
Amgen Inc. |
Anti-steap1 antigen-binding protein
|
TW202021616A
(zh)
|
2018-07-30 |
2020-06-16 |
美商安進公司 |
結合至cd33和cd3的雙特異性抗體構建體之延長投與
|
TW202019477A
(zh)
|
2018-07-31 |
2020-06-01 |
德商安美基研究(慕尼黑)公司 |
BCMAxCD3抗體構建體之給藥方案
|
US11692031B2
(en)
|
2018-08-03 |
2023-07-04 |
Amgen Research (Munich) Gmbh |
Antibody constructs for CLDN18.2 and CD3
|
AU2019331024A1
(en)
|
2018-08-31 |
2021-03-18 |
Regeneron Pharmaceuticals, Inc. |
Dosing strategy that mitigates cytokine release syndrome for CD3/C20 bispecific antibodies
|
US11066476B2
(en)
|
2018-09-14 |
2021-07-20 |
Shanghai tongji hospital |
Asymmetric bispecific antibody
|
CN110590955B
(zh)
*
|
2018-09-17 |
2021-05-18 |
北京盛诺基医药科技股份有限公司 |
一种双特异性抗体
|
JP2022500095A
(ja)
|
2018-09-24 |
2022-01-04 |
アムジエン・インコーポレーテツド |
インターベンション投薬システム及び方法
|
MA53732A
(fr)
|
2018-09-28 |
2022-01-05 |
Amgen Inc |
Anticorps dirigés contre bcma soluble
|
SG11202103192RA
(en)
|
2018-10-03 |
2021-04-29 |
Xencor Inc |
Il-12 heterodimeric fc-fusion proteins
|
WO2020077212A1
(en)
|
2018-10-11 |
2020-04-16 |
Amgen Inc. |
Downstream processing of bispecific antibody constructs
|
MX2021004510A
(es)
|
2018-10-23 |
2021-06-08 |
Amgen Inc |
Calibracion automatica y mantenimiento automatico de modelos espectroscopicos de raman para predicciones en tiempo real.
|
US11279698B2
(en)
|
2018-11-20 |
2022-03-22 |
Cornell University |
Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer
|
WO2020132214A2
(en)
|
2018-12-20 |
2020-06-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Ebola virus glycoprotein-specific monoclonal antibodies and uses thereof
|
TW202043253A
(zh)
|
2019-01-28 |
2020-12-01 |
美商安進公司 |
藉由將藥物物質和藥物產品過程整體化的生物製劑製造之連續製造過程
|
EP3928101A1
(de)
|
2019-02-20 |
2021-12-29 |
Amgen Inc. |
Verfahren zur bestimmung der proteinstabilität
|
WO2020180726A1
(en)
|
2019-03-01 |
2020-09-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind enpp3 and cd3
|
US11685780B2
(en)
|
2019-03-05 |
2023-06-27 |
Takeda Pharmaceutical Company Limited |
Single domain antigen binding domains that bind human Trop2
|
CA3133459A1
(en)
|
2019-03-27 |
2020-10-01 |
Amgen Inc. |
Methods of fingerprinting therapeutic proteins via a two-dimensional (2d) nuclear magnetic resonance technique at natural abundance for formulated biopharmaceutical products
|
US20220204620A1
(en)
|
2019-04-30 |
2022-06-30 |
Amgen Research (Munich) Gmbh |
Means and methods for treating burkitt lymphoma or leukemia
|
EP3962523A2
(de)
|
2019-05-03 |
2022-03-09 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Neutralisierende antikörper gegen das plasmodium-falciparum-circumsporozoit-protein und verwendung davon
|
US20230085439A1
(en)
|
2019-05-21 |
2023-03-16 |
University Of Georgia Research Foundation, Inc. |
Antibodies that bind human metapneumovirus fusion protein and their use
|
MA56110A
(fr)
|
2019-06-07 |
2022-04-13 |
Amgen Inc |
Constructions de liaison bispécifiques à lieurs clivables de manière sélective
|
TW202045711A
(zh)
|
2019-06-13 |
2020-12-16 |
美商安進公司 |
生物製品製造中基於生物量之自動灌注控制
|
WO2021003297A1
(en)
|
2019-07-02 |
2021-01-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies that bind egfrviii and their use
|
CN110623921B
(zh)
*
|
2019-08-15 |
2020-10-30 |
北京东方百泰生物科技股份有限公司 |
一种抗cd3和抗cd19的双特异性抗体注射制剂
|
RU2738802C1
(ru)
*
|
2019-08-21 |
2020-12-17 |
Общество с ограниченной ответственностью "Международный Биотехнологический Центр "Генериум" |
Определяющие комплементарность участки для связывания cd3 и содержащая их биспецифическая антигенсвязывающая молекула
|
GB201912681D0
(en)
|
2019-09-04 |
2019-10-16 |
Eth Zuerich |
Bispecific binding agent that binds to cd117/c-kit and cd3
|
CA3152946A1
(en)
|
2019-09-10 |
2021-03-18 |
Amgen Inc. |
Purification method for bispecific antigen-binding polypeptides with enhanced protein l capture dynamic binding capacity
|
WO2021064189A2
(en)
|
2019-10-02 |
2021-04-08 |
Domain Therapeutics |
Prostaglandin e2 (pge2) ep4 receptor antagonists
|
CA3157896A1
(en)
|
2019-10-16 |
2021-04-22 |
Cemm - Forschungszentrum Fur Molekulare Medizin Gmbh |
Oxazole and thioazole-type cullin ring ubiquitin ligase compounds and uses thereof
|
WO2021074418A1
(en)
|
2019-10-16 |
2021-04-22 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Carbazole-type cullin ring ubiquitin ligase compounds and uses thereof
|
EP3808741A1
(de)
|
2019-10-16 |
2021-04-21 |
CeMM - Forschungszentrum für Molekulare Medizin GmbH |
Verbindungen für den gezielten abbau von trägerproteinen und verwendungen davon
|
US20220389099A1
(en)
|
2019-11-04 |
2022-12-08 |
Amgen Inc. |
Methods for treating leukemia
|
EP3819312A1
(de)
|
2019-11-10 |
2021-05-12 |
Amgen, Inc |
Dosierschema für anti-dll3-wirkstoffe
|
EP3819007A1
(de)
|
2019-11-11 |
2021-05-12 |
Amgen Research (Munich) GmbH |
Dosierschema für anti-bcma-wirkstoffe
|
CA3156683A1
(en)
|
2019-11-13 |
2021-05-20 |
Amgen Inc. |
METHOD FOR REDUCING AGGREGATE FORMATION IN DOWNSTREAM PROCESSING OF BI-SPECIFIC ANTIGEN-BINDING MOLECULES
|
WO2021150824A1
(en)
|
2020-01-22 |
2021-07-29 |
Amgen Research (Munich) Gmbh |
Combinations of antibody constructs and inhibitors of cytokine release syndrome and uses thereof
|
KR20220144377A
(ko)
|
2020-01-30 |
2022-10-26 |
우모자 바이오파마 인코포레이티드 |
이중특이적 형질도입 촉진제
|
US20230071627A1
(en)
|
2020-02-03 |
2023-03-09 |
Amgen Inc. |
Multivariate Bracketing Approach for Sterile Filter Validation
|
TW202140561A
(zh)
|
2020-02-14 |
2021-11-01 |
日商協和麒麟股份有限公司 |
與cd3結合之雙特異性抗體
|
KR20220145859A
(ko)
|
2020-02-28 |
2022-10-31 |
상하이 헨리우스 바이오테크, 인크. |
항cd137 작제물, 다중 특이적 항체 및 그 용도
|
JP2023516945A
(ja)
|
2020-02-28 |
2023-04-21 |
上海復宏漢霖生物技術股▲フン▼有限公司 |
抗cd137コンストラクト及びその使用
|
AU2021232853A1
(en)
|
2020-03-10 |
2022-09-22 |
Massachusetts Institute Of Technology |
Compositions and methods for immunotherapy of NPM1c-positive cancer
|
EP4118113A1
(de)
|
2020-03-12 |
2023-01-18 |
Amgen Inc. |
Verfahren zur behandlung und prophylaxe von crs bei patienten mit einer kombination aus bispezifischen antikörpern zur bindung an cds x-krebszellen und tnfalpha- oder il-6-hemmer
|
WO2021188851A1
(en)
|
2020-03-19 |
2021-09-23 |
Amgen Inc. |
Antibodies against mucin 17 and uses thereof
|
US11919956B2
(en)
|
2020-05-14 |
2024-03-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3
|
JP2023527293A
(ja)
|
2020-05-19 |
2023-06-28 |
アムジエン・インコーポレーテツド |
Mageb2結合構築物
|
EP4157874A2
(de)
|
2020-05-29 |
2023-04-05 |
Amgen Inc. |
Die nebenwirkungen mindernde verabreichung eines bispezifischen antikörperkonstrukts, das an cd33 und cd3 bindet
|
CN116529260A
(zh)
|
2020-06-02 |
2023-08-01 |
当康生物技术有限责任公司 |
抗cd93构建体及其用途
|
WO2021247769A1
(en)
|
2020-06-02 |
2021-12-09 |
Dynamicure Biotechnology Llc |
Anti-cd93 constructs and uses thereof
|
US20230203198A1
(en)
|
2020-06-04 |
2023-06-29 |
Amgen Inc. |
Bispecific binding constructs
|
MX2023001083A
(es)
|
2020-07-29 |
2023-04-10 |
Dynamicure Biotechnology Llc |
Construcciones anti grupo de diferenciacion 93 (cd93) y usos de las mismas.
|
MX2023001962A
(es)
|
2020-08-19 |
2023-04-26 |
Xencor Inc |
Composiciones anti-cd28.
|
AU2021331170A1
(en)
|
2020-08-27 |
2023-03-23 |
Juntendo Educational Foundation |
Anti-cleaved mutant calr-cd3 bispecific antibody and pharmaceutical composition
|
WO2022056267A1
(en)
|
2020-09-11 |
2022-03-17 |
Amgen Inc. |
Materials and methods to reduce protein aggregation
|
JP2023542257A
(ja)
|
2020-09-16 |
2023-10-05 |
アムジェン インコーポレイテッド |
癌の治療のために二重特異性t細胞誘導分子の治療用量を投与する方法
|
WO2022060878A1
(en)
|
2020-09-16 |
2022-03-24 |
Amgen Inc. |
Methods for treating prostate cancer
|
JP2023545588A
(ja)
|
2020-10-16 |
2023-10-30 |
ツェーエムエム-フォルシュングスツェントルム フュア モレクラレ メディツィン ゲーエムベーハー |
ヘテロ環式カリンringユビキチンリガーゼ化合物及びその使用
|
EP4240407A1
(de)
|
2020-11-06 |
2023-09-13 |
Amgen Inc. |
Antigenbindende domäne mit reduzierter clipping-rate
|
EP4240767A1
(de)
|
2020-11-06 |
2023-09-13 |
Amgen Inc. |
An cd3 bindende polypeptidkonstrukte
|
CA3199976A1
(en)
|
2020-11-06 |
2022-05-12 |
Amgen Research (Munich) Gmbh |
Polypeptide constructs selectively binding to cldn6 and cd3
|
UY39508A
(es)
|
2020-11-06 |
2022-05-31 |
Amgen Res Munich Gmbh |
Moléculas de unión a antígeno biespecíficas con múltiples dianas de selectividad aumentada
|
WO2022103781A1
(en)
|
2020-11-10 |
2022-05-19 |
Amgen Inc. |
Methods for administering a bcma x cd3 binding molecule
|
CA3203468A1
(en)
|
2020-12-03 |
2022-06-09 |
Amgen Inc. |
Immunoglobuline constructs with multiple binding domains
|
WO2022132904A1
(en)
|
2020-12-17 |
2022-06-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies targeting sars-cov-2
|
WO2022129637A1
(en)
|
2020-12-18 |
2022-06-23 |
Ablynx Nv |
T cell recruiting polypeptides based on tcr alpha/beta reactivity
|
EP4281484A1
(de)
|
2021-01-22 |
2023-11-29 |
Bionecure Therapeutics, Inc. |
Anti-her-2/trop-2-konstrukte und verwendungen davon
|
EP4284512A1
(de)
|
2021-01-28 |
2023-12-06 |
Regeneron Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren zur behandlung des zytokinfreisetzungssyndroms
|
JP2024506315A
(ja)
|
2021-02-09 |
2024-02-13 |
ザ ユナイテッド ステイツ オブ アメリカ アズ リプリゼンテッド バイ ザ セクレタリー、デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
コロナウイルスのスパイクタンパク質を標的とする抗体
|
WO2022173689A1
(en)
|
2021-02-09 |
2022-08-18 |
University Of Georgia Research Foundation, Inc. |
Human monoclonal antibodies against pneumococcal antigens
|
CN115105600A
(zh)
|
2021-02-10 |
2022-09-27 |
同润生物医药(上海)有限公司 |
一种PI3Kδ/γ的药物组合及其治疗肿瘤的方法
|
WO2022192403A1
(en)
|
2021-03-09 |
2022-09-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cldn6
|
CA3208770A1
(en)
|
2021-03-10 |
2022-09-15 |
Amgen Inc. |
Parallel chromatography systems and methods
|
EP4305065A1
(de)
|
2021-03-10 |
2024-01-17 |
Xencor, Inc. |
Cd3 und gpc3 bindende heterodimere antikörper
|
CN117043173A
(zh)
|
2021-03-10 |
2023-11-10 |
美国安进公司 |
重组蛋白的纯化方法
|
EP4314049A1
(de)
|
2021-03-25 |
2024-02-07 |
Dynamicure Biotechnology LLC |
Anti-igfbp7-konstrukte und verwendungen davon
|
CN112794916B
(zh)
*
|
2021-04-08 |
2021-08-10 |
正大天晴药业集团南京顺欣制药有限公司 |
三特异性抗原结合构建体及构建方法和应用
|
CN117279947A
(zh)
|
2021-05-06 |
2023-12-22 |
安进研发(慕尼黑)股份有限公司 |
用于在增殖性疾病中使用的靶向cd20和cd22的抗原结合分子
|
WO2022266660A1
(en)
|
2021-06-17 |
2022-12-22 |
Amberstone Biosciences, Inc. |
Anti-cd3 constructs and uses thereof
|
CA3232223A1
(en)
|
2021-09-17 |
2023-03-23 |
Ying Fu |
Synthetic humanized llama nanobody library and use thereof to identify sars-cov-2 neutralizing antibodies
|
WO2023062188A1
(en)
|
2021-10-15 |
2023-04-20 |
Amgen Research (Munich) Gmbh |
Subcutaneous administration of cd19-binding t cell engaging antibodies
|
AU2022379497A1
(en)
|
2021-10-27 |
2024-05-02 |
Amgen Inc. |
Deep learning-based prediction for monitoring of pharmaceuticals using spectroscopy
|
EP4180035A1
(de)
|
2021-11-15 |
2023-05-17 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Neue beta-lacton inhibitoren von hydrolytischen enzymen und ihre medizinische und nicht-medizinische verwendungen
|
WO2023110918A1
(en)
|
2021-12-14 |
2023-06-22 |
Cdr-Life Ag |
Dual mhc-targeting t cell engager
|
WO2023154824A1
(en)
|
2022-02-10 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies that broadly target coronaviruses
|
WO2023164474A1
(en)
|
2022-02-23 |
2023-08-31 |
Amgen Inc. |
Cancer treatment targeting dll3
|
WO2023192881A1
(en)
|
2022-03-28 |
2023-10-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
US20230357446A1
(en)
|
2022-04-11 |
2023-11-09 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for universal tumor cell killing
|
WO2023203174A1
(en)
|
2022-04-20 |
2023-10-26 |
Proxygen Gmbh |
Heterocyclic cullin ring ubiquitin ligase compounds and uses thereof
|
TW202346368A
(zh)
|
2022-05-12 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
具有增加的選擇性的多鏈多靶向性雙特異性抗原結合分子
|
US20240117062A1
(en)
|
2022-05-27 |
2024-04-11 |
Sanofi |
Anti-bcma antibodies
|
US20240109965A1
(en)
|
2022-06-14 |
2024-04-04 |
Ablynx N.V. |
Immunoglobulin single variable domains targeting t cell receptor
|
WO2024030829A1
(en)
|
2022-08-01 |
2024-02-08 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies that bind to the underside of influenza viral neuraminidase
|
WO2024054822A1
(en)
|
2022-09-07 |
2024-03-14 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Engineered sars-cov-2 antibodies with increased neutralization breadth
|
WO2024056758A1
(en)
|
2022-09-14 |
2024-03-21 |
Cdr-Life Ag |
Mage-a4 peptide dual t cell engagers
|
WO2024059675A2
(en)
|
2022-09-14 |
2024-03-21 |
Amgen Inc. |
Bispecific molecule stabilizing composition
|
WO2024064826A1
(en)
|
2022-09-22 |
2024-03-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
|
WO2024068944A1
(en)
|
2022-09-30 |
2024-04-04 |
Sanofi |
Anti-cd28 antibodies
|
WO2024077044A1
(en)
|
2022-10-05 |
2024-04-11 |
Amgen Inc. |
Combination therapies comprising t-cell redirecting therapies and agonistic anti-il-2r antibodies or fragments thereof
|
WO2024092033A1
(en)
|
2022-10-26 |
2024-05-02 |
Amgen Inc. |
Multispecific molecules for clearance of immunoglobulins in the treatment of autoantibody-induced diseases
|