HK1202795A1 - Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same epa - Google Patents

Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same epa

Info

Publication number
HK1202795A1
HK1202795A1 HK15102705.5A HK15102705A HK1202795A1 HK 1202795 A1 HK1202795 A1 HK 1202795A1 HK 15102705 A HK15102705 A HK 15102705A HK 1202795 A1 HK1202795 A1 HK 1202795A1
Authority
HK
Hong Kong
Prior art keywords
epa
methods
pharmaceutical compositions
same
cardiovascular agent
Prior art date
Application number
HK15102705.5A
Other languages
English (en)
Chinese (zh)
Inventor
曼庫‧梅哈爾
羅‧喬納森
Original Assignee
Amarin Pharmaceuticals Ie Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amarin Pharmaceuticals Ie Ltd filed Critical Amarin Pharmaceuticals Ie Ltd
Publication of HK1202795A1 publication Critical patent/HK1202795A1/xx

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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    • A—HUMAN NECESSITIES
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
HK15102705.5A 2009-04-29 2015-03-17 Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same epa HK1202795A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17375909P 2009-04-29 2009-04-29

Publications (1)

Publication Number Publication Date
HK1202795A1 true HK1202795A1 (en) 2015-10-09

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Family Applications (1)

Application Number Title Priority Date Filing Date
HK15102705.5A HK1202795A1 (en) 2009-04-29 2015-03-17 Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same epa

Country Status (16)

Country Link
US (27) US11033523B2 (xx)
EP (4) EP3563842A1 (xx)
KR (1) KR101357438B1 (xx)
CN (4) CN107233337A (xx)
AU (1) AU2010241567B2 (xx)
BR (1) BRPI1014405A2 (xx)
CA (1) CA2759176C (xx)
CO (1) CO6470839A2 (xx)
HK (1) HK1202795A1 (xx)
MX (3) MX2011011517A (xx)
MY (2) MY198422A (xx)
NZ (5) NZ771180A (xx)
RU (5) RU2489145C1 (xx)
SG (1) SG175390A1 (xx)
WO (1) WO2010127099A2 (xx)
ZA (1) ZA201107623B (xx)

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CA2992231C (en) 2009-03-18 2022-03-29 Resverlogix Corp. Phenyl-quinazolin-4(3h)-one and phenyl-pyrido[2,3-d]pyrimidin-4(3h)-one derivatives and compositions thereof useful as anti-inflammatory agents
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EP3563842A1 (en) 2009-04-29 2019-11-06 Amarin Pharmaceuticals Ireland Limited Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
RU2538691C2 (ru) 2009-04-29 2015-01-10 Амарин Фарма, Инк. Стабильные фармацевтические композиции и способы их применения
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US11712429B2 (en) 2010-11-29 2023-08-01 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
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US20120302639A1 (en) * 2011-02-16 2012-11-29 Pivotal Therapeutics Inc. Omega 3 formulations for treatment of risk factors for cardiovascular disease and protection against sudden death
US8952000B2 (en) * 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Cholesterol absorption inhibitor and omega 3 fatty acids for the reduction of cholesterol and for the prevention or reduction of cardiovascular, cardiac and vascular events
WO2014037832A2 (en) 2012-09-06 2014-03-13 Mahesh Kandula Compositions and methods for the treatment of epilepsy and neurological diseases
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US20130195972A1 (en) 2013-08-01
EP3563842A1 (en) 2019-11-06
RU2017145265A3 (xx) 2021-09-17
RU2011148363A (ru) 2013-06-10
US20210000779A1 (en) 2021-01-07
RU2746945C2 (ru) 2021-04-22
US8563608B2 (en) 2013-10-22
RU2017121277A3 (xx) 2020-08-10
ZA201107623B (en) 2014-06-25
CN106822080A (zh) 2017-06-13
RU2017145265A (ru) 2019-06-24
US20220079907A1 (en) 2022-03-17
CN102413825A (zh) 2012-04-11
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US20180042880A1 (en) 2018-02-15
MY198422A (en) 2023-08-29
NZ752610A (en) 2021-01-29
CA2759176C (en) 2016-03-15
BRPI1014405A2 (pt) 2016-04-05
RU2013116807A (ru) 2014-10-20
US20130005757A1 (en) 2013-01-03
US20150272917A1 (en) 2015-10-01
US8691871B2 (en) 2014-04-08
US11690820B2 (en) 2023-07-04
NZ771180A (en) 2022-07-29
US10792267B2 (en) 2020-10-06
EP4008327A1 (en) 2022-06-08
RU2489145C1 (ru) 2013-08-10
US20140155455A1 (en) 2014-06-05
US9855237B2 (en) 2018-01-02
US20150231102A1 (en) 2015-08-20
EP2424521A2 (en) 2012-03-07
MY173994A (en) 2020-03-03
RU2017121277A (ru) 2018-12-19
CO6470839A2 (es) 2012-06-29
RU2013106526A (ru) 2014-08-20
EP3791880A1 (en) 2021-03-17
US11400069B2 (en) 2022-08-02
SG175390A1 (en) 2011-12-29
MX2011011517A (es) 2012-06-19
KR101357438B1 (ko) 2014-02-06
US10624870B2 (en) 2020-04-21
US20120093922A1 (en) 2012-04-19
US20130253030A1 (en) 2013-09-26
US8618166B2 (en) 2013-12-31
US20210379002A1 (en) 2021-12-09
NZ624963A (en) 2016-07-29
NZ789295A (en) 2024-02-23
US10987331B2 (en) 2021-04-27
EP2424521A4 (en) 2015-03-04
MX2022009942A (es) 2022-09-12
RU2648826C2 (ru) 2018-03-28
US20220079906A1 (en) 2022-03-17
RU2624506C2 (ru) 2017-07-04
RU2022100434A (ru) 2022-03-11
US20200121628A1 (en) 2020-04-23
WO2010127099A3 (en) 2014-03-20
US20140154310A1 (en) 2014-06-05
US20220241234A1 (en) 2022-08-04
US20190070141A1 (en) 2019-03-07
US20210100765A1 (en) 2021-04-08
US20190183831A1 (en) 2019-06-20
US20210100764A1 (en) 2021-04-08
US9056088B2 (en) 2015-06-16
US20120121698A1 (en) 2012-05-17
US20120172432A1 (en) 2012-07-05
NZ734905A (en) 2019-05-31
US20210212974A1 (en) 2021-07-15
CN104042617A (zh) 2014-09-17
US8680144B2 (en) 2014-03-25
AU2010241567B2 (en) 2013-10-31
US10888537B2 (en) 2021-01-12
KR20120089563A (ko) 2012-08-13
NZ595789A (en) 2014-05-30
US11154526B2 (en) 2021-10-26
US10220013B2 (en) 2019-03-05
AU2010241567A1 (en) 2011-11-10
US11033523B2 (en) 2021-06-15

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