ID18983A - Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusia - Google Patents
Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusiaInfo
- Publication number
- ID18983A ID18983A IDP973793A ID973793A ID18983A ID 18983 A ID18983 A ID 18983A ID P973793 A IDP973793 A ID P973793A ID 973793 A ID973793 A ID 973793A ID 18983 A ID18983 A ID 18983A
- Authority
- ID
- Indonesia
- Prior art keywords
- secression
- pirazola
- secretary
- human
- pancreas phospholipase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3321696P | 1996-12-04 | 1996-12-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID18983A true ID18983A (id) | 1998-05-28 |
Family
ID=21869147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDP973793A ID18983A (id) | 1996-12-04 | 1997-11-27 | Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusia |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5972972A (id) |
| EP (1) | EP0846687B1 (id) |
| JP (1) | JP2002515053A (id) |
| KR (1) | KR20000057366A (id) |
| AR (1) | AR010743A1 (id) |
| AT (1) | ATE203985T1 (id) |
| AU (1) | AU5365598A (id) |
| BR (1) | BR9713993A (id) |
| CA (1) | CA2274048A1 (id) |
| CO (1) | CO4910169A1 (id) |
| DE (1) | DE69706027T2 (id) |
| DK (1) | DK0846687T3 (id) |
| ES (1) | ES2160897T3 (id) |
| HU (1) | HUP0000292A3 (id) |
| ID (1) | ID18983A (id) |
| IL (1) | IL130202A0 (id) |
| PE (1) | PE20599A1 (id) |
| PT (1) | PT846687E (id) |
| TW (1) | TW432051B (id) |
| WO (1) | WO1998024437A1 (id) |
| ZA (1) | ZA9710878B (id) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6979686B1 (en) | 2001-12-07 | 2005-12-27 | Pharmacia Corporation | Substituted pyrazoles as p38 kinase inhibitors |
| AU7726898A (en) | 1997-05-22 | 1998-12-11 | G.D. Searle & Co. | Pyrazole derivatives as p38 kinase inhibitors |
| US6514977B1 (en) | 1997-05-22 | 2003-02-04 | G.D. Searle & Company | Substituted pyrazoles as p38 kinase inhibitors |
| WO1999051605A1 (en) | 1998-03-31 | 1999-10-14 | Shionogi & Co., Ltd. | PYRROLO[1,2-a]PYRAZINE sPLA2 INHIBITOR |
| US6472389B1 (en) | 1998-05-21 | 2002-10-29 | Shionogi & Co., Ltd. | Pyrrolo[1,2-b] pyridazine derivatives having sPLA2 inhibitory effect |
| CA2346334A1 (en) | 1998-10-14 | 2000-04-20 | Shionogi & Co., Ltd. | Composition for treating or preventing ischemia reperfusion injury |
| JP4636521B2 (ja) | 1999-07-19 | 2011-02-23 | 塩野義製薬株式会社 | ｓＰＬＡ２阻害作用を有する三環系化合物 |
| JP4636522B2 (ja) | 1999-08-02 | 2011-02-23 | 塩野義製薬株式会社 | ｓＰＬＡ２阻害作用を有する三環式化合物 |
| WO2001014378A1 (en) | 1999-08-23 | 2001-03-01 | Shionogi & Co., Ltd. | PYRROLOTRIAZINE DERIVATIVES HAVING sPLA2-INHIBITORY ACTIVITIES |
| ES2171116B1 (es) * | 2000-04-14 | 2003-08-01 | Esteve Quimica Sa | Procedimiento para la obtencion de derivados de (((piridil sustituido)metil)tio)bencimidazol. |
| JPWO2002000621A1 (ja) | 2000-06-29 | 2004-04-22 | 塩野義製薬株式会社 | Ｘ型ｓＰＬＡ２阻害作用を有する化合物 |
| WO2002000256A1 (fr) | 2000-06-29 | 2002-01-03 | Shionogi & Co., Ltd. | Remedes contre la cirrhose |
| TWI314457B (id) | 2001-03-19 | 2009-09-11 | Shionogi & Co | |
| US7076539B2 (en) * | 2001-07-30 | 2006-07-11 | Hewlett-Packard Development Company, L.P. | Network connectivity establishment at user log-in |
| WO2003101177A2 (en) * | 2002-06-04 | 2003-12-11 | Sequenom, Inc. | Diagnosing predisposition to fat deposition and therapeutic methods for reducing fat deposition and treatment of associated conditions |
| AUPS282602A0 (en) | 2002-06-07 | 2002-06-27 | Garvan Institute Of Medical Research | Method of inhibiting cell proliferation |
| US20050014158A1 (en) * | 2002-06-27 | 2005-01-20 | Adam Gail Isabel Reid | Therapeutic methods for reducing fat deposition and treating associated conditions |
| WO2004002295A2 (en) * | 2002-06-27 | 2004-01-08 | Sequenom, Inc. | Diagnosing predisposition to fat deposition and associated condition |
| CN102924412A (zh) * | 2008-01-25 | 2013-02-13 | 先正达参股股份有限公司 | 用作杀虫剂的2-氰基苯基磺酰胺衍生物 |
| CN107233337A (zh) | 2009-04-29 | 2017-10-10 | 阿马里纳药物爱尔兰有限公司 | 含有epa和心血管剂的药物组合物以及使用其的方法 |
| CN105017134A (zh) * | 2015-07-26 | 2015-11-04 | 陈吉美 | 一种4-吡啶丙烯酸的制备方法 |
| EP3752510B1 (en) | 2018-02-15 | 2022-12-07 | Vertex Pharmaceuticals Incorporated | Macrocycles as modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions thereof, their use in the treatment of cycstic fibrosis, and process for making them |
| US12479816B2 (en) | 2019-02-08 | 2025-11-25 | University of Pittsburgh—of the Commonwealth System of Higher Education | 20-HETE formation inhibitors |
| TWI848092B (zh) | 2019-04-03 | 2024-07-11 | 美商維泰克斯製藥公司 | 囊腫纖維化跨膜傳導調節蛋白調節劑 |
| TWI867024B (zh) | 2019-08-14 | 2024-12-21 | 美商維泰克斯製藥公司 | 囊腫纖維化跨膜傳導調節蛋白之調節劑 |
| TWI899097B (zh) | 2019-08-14 | 2025-10-01 | 美商維泰克斯製藥公司 | 製備cftr調節劑之方法 |
| KR20220064366A (ko) | 2019-08-14 | 2022-05-18 | 버텍스 파마슈티칼스 인코포레이티드 | Cftr 조절제의 결정질 형태 |
| EP4225737A1 (en) * | 2020-10-07 | 2023-08-16 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
| CA3204725A1 (en) | 2020-12-10 | 2022-06-16 | Vertex Pharmaceuticals Incorporated | Methods of treatment for cystic fibrosis |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3616681A1 (de) * | 1986-05-16 | 1987-11-19 | Bayer Ag | 1-aralkylpyrazole |
| JPH02229168A (ja) * | 1989-03-01 | 1990-09-11 | Takeda Chem Ind Ltd | ピラゾロン誘導体 |
| JPH02229169A (ja) * | 1989-03-01 | 1990-09-11 | Takeda Chem Ind Ltd | ピラゾロン誘導体 |
| ATE157969T1 (de) * | 1990-07-10 | 1997-09-15 | Ishihara Sangyo Kaisha | Diaminotrifluoromethylpyrimidinderivate, verfahren zu ihrer herstellung und diese enthaltende phospholipase-a2-inhibitoren |
| EP0539034A1 (en) * | 1991-10-22 | 1993-04-28 | Konica Corporation | A novel photographic cyan coupler |
| US5541213A (en) * | 1993-06-24 | 1996-07-30 | Eisai Co., Ltd. | Propenoic acid derivatives diazole propenoic acid compounds which have useful pharmaceutical utility |
| US5466823A (en) * | 1993-11-30 | 1995-11-14 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides |
| US5500439A (en) * | 1993-12-09 | 1996-03-19 | Alteon Inc. | Aminopyrazoles |
| US5559137A (en) * | 1994-05-16 | 1996-09-24 | Smithkline Beecham Corp. | Compounds |
| US5486534A (en) * | 1994-07-21 | 1996-01-23 | G. D. Searle & Co. | 3,4-substituted pyrazoles for the treatment of inflammation |
-
1997
- 1997-11-27 ID IDP973793A patent/ID18983A/id unknown
- 1997-12-01 HU HU0000292A patent/HUP0000292A3/hu unknown
- 1997-12-01 CA CA002274048A patent/CA2274048A1/en not_active Abandoned
- 1997-12-01 KR KR1019990704898A patent/KR20000057366A/ko not_active Withdrawn
- 1997-12-01 WO PCT/US1997/021795 patent/WO1998024437A1/en not_active Ceased
- 1997-12-01 IL IL13020297A patent/IL130202A0/xx unknown
- 1997-12-01 AU AU53655/98A patent/AU5365598A/en not_active Abandoned
- 1997-12-01 BR BR9713993-9A patent/BR9713993A/pt unknown
- 1997-12-01 JP JP52568198A patent/JP2002515053A/ja not_active Withdrawn
- 1997-12-01 PE PE1997001083A patent/PE20599A1/es not_active Application Discontinuation
- 1997-12-02 CO CO97070453A patent/CO4910169A1/es unknown
- 1997-12-02 DK DK97309701T patent/DK0846687T3/da active
- 1997-12-02 AT AT97309701T patent/ATE203985T1/de not_active IP Right Cessation
- 1997-12-02 EP EP97309701A patent/EP0846687B1/en not_active Expired - Lifetime
- 1997-12-02 PT PT97309701T patent/PT846687E/pt unknown
- 1997-12-02 DE DE69706027T patent/DE69706027T2/de not_active Expired - Fee Related
- 1997-12-02 ES ES97309701T patent/ES2160897T3/es not_active Expired - Lifetime
- 1997-12-03 AR ARP970105678A patent/AR010743A1/es unknown
- 1997-12-03 ZA ZA9710878A patent/ZA9710878B/xx unknown
- 1997-12-03 US US08/984,261 patent/US5972972A/en not_active Expired - Fee Related
- 1997-12-05 TW TW086118237A patent/TW432051B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0846687A1 (en) | 1998-06-10 |
| DE69706027T2 (de) | 2002-03-14 |
| EP0846687B1 (en) | 2001-08-08 |
| IL130202A0 (en) | 2000-06-01 |
| CA2274048A1 (en) | 1998-06-11 |
| ATE203985T1 (de) | 2001-08-15 |
| TW432051B (en) | 2001-05-01 |
| KR20000057366A (ko) | 2000-09-15 |
| PT846687E (pt) | 2001-12-28 |
| ES2160897T3 (es) | 2001-11-16 |
| HK1011865A1 (en) | 1999-07-23 |
| BR9713993A (pt) | 2000-02-08 |
| AR010743A1 (es) | 2000-07-12 |
| AU5365598A (en) | 1998-06-29 |
| DE69706027D1 (de) | 2001-09-13 |
| CO4910169A1 (es) | 2000-04-24 |
| PE20599A1 (es) | 1999-03-05 |
| WO1998024437A1 (en) | 1998-06-11 |
| HUP0000292A3 (en) | 2002-01-28 |
| JP2002515053A (ja) | 2002-05-21 |
| DK0846687T3 (da) | 2001-10-08 |
| US5972972A (en) | 1999-10-26 |
| ZA9710878B (en) | 1999-06-03 |
| HUP0000292A2 (hu) | 2001-04-28 |
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