MX2016016830A - Complejos de aminoacidos minerales de agentes activos. - Google Patents
Complejos de aminoacidos minerales de agentes activos.Info
- Publication number
- MX2016016830A MX2016016830A MX2016016830A MX2016016830A MX2016016830A MX 2016016830 A MX2016016830 A MX 2016016830A MX 2016016830 A MX2016016830 A MX 2016016830A MX 2016016830 A MX2016016830 A MX 2016016830A MX 2016016830 A MX2016016830 A MX 2016016830A
- Authority
- MX
- Mexico
- Prior art keywords
- formula
- different
- same
- fatty acids
- application
- Prior art date
Links
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 title 1
- 229910052500 inorganic mineral Inorganic materials 0.000 title 1
- 239000011707 mineral Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- -1 Magnesium Lysinate bis docosapentaenoic acid Chemical compound 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 239000002778 food additive Substances 0.000 abstract 1
- 235000013373 food additive Nutrition 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
Classifications
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- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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- A23L33/175—Amino acids
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- A23L33/18—Peptides; Protein hydrolysates
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- A61K31/19—Carboxylic acids, e.g. valproic acid
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- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
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- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/76—Metal complexes of amino carboxylic acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/126—Acids containing more than four carbon atoms
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/03—Monocarboxylic acids
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/03—Monocarboxylic acids
- C07C57/12—Straight chain carboxylic acids containing eighteen carbon atoms
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- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
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- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
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- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/02—Magnesium compounds
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- C07F3/06—Zinc compounds
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- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
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- Pain & Pain Management (AREA)
- Psychiatry (AREA)
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Abstract
La presente invención proporciona compuestos de la Fórmula I y composiciones y métodos relacionados. (ver Fórmula) R1 y R2 cada uno se refiere a una cadena de carbono ramificada o no ramificada desde 1 hasta 20 carbonos que tiene al menos una función básica; R1 y R2 son los mismos o diferentes; X1 y X2 son independientemente seleccionados de H y -CO-Z, donde Z es una porción de péptido que incorpora desde 1 hasta 5 aminoácidos, o una sal farmacéuticamente aceptable de los mismos; X1 y X2 son los mismos o diferentes; M es un catión de metal divalente seleccionado de magnesio (Mg2+), calcio (Ca2+), y zinc (Zn2+); A y B son cada uno una molécula que tiene al menos una función ácida, ya sea A o B, pero no ambos, pueden estar ausentes, y cuando tanto A como B están presentes, A y B pueden ser el mismo o diferente. En una modalidad particular, al menos uno de ``A´´ o ``B´´, o ambos, son ácidos grasos. Un ejemplo representativo de la solicitud es el compuesto Ácido lisinato bis docosapentanoico de magnesio (ver Fórmula) Los complejos de la solicitud se pretenden para composiciones farmacéuticas como aditivos para alimentos, notablemente para tratar afecciones que responden al tratamiento con ácidos grasos poliinsaturados.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201462013904P | 2014-06-18 | 2014-06-18 | |
US201462058491P | 2014-10-01 | 2014-10-01 | |
PCT/US2015/035686 WO2015195491A1 (en) | 2014-06-18 | 2015-06-12 | Mineral amino-acid complexes of active agents |
Publications (1)
Publication Number | Publication Date |
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MX2016016830A true MX2016016830A (es) | 2017-07-07 |
Family
ID=53514393
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016016830A MX2016016830A (es) | 2014-06-18 | 2015-06-12 | Complejos de aminoacidos minerales de agentes activos. |
Country Status (14)
Country | Link |
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US (1) | US9999626B2 (es) |
EP (1) | EP3157936B1 (es) |
JP (1) | JP2017526623A (es) |
KR (1) | KR20170023061A (es) |
CN (1) | CN107074884A (es) |
AU (1) | AU2015277509A1 (es) |
BR (1) | BR112016029476A2 (es) |
CA (1) | CA2951923A1 (es) |
DK (1) | DK3157936T3 (es) |
EA (1) | EA201692548A1 (es) |
ES (1) | ES2706493T3 (es) |
IL (1) | IL249455A0 (es) |
MX (1) | MX2016016830A (es) |
WO (1) | WO2015195491A1 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
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- 2015-06-12 EP EP15734490.4A patent/EP3157936B1/en active Active
- 2015-06-12 KR KR1020177000095A patent/KR20170023061A/ko not_active Application Discontinuation
- 2015-06-12 JP JP2016573816A patent/JP2017526623A/ja active Pending
- 2015-06-12 DK DK15734490.4T patent/DK3157936T3/en active
- 2015-06-12 MX MX2016016830A patent/MX2016016830A/es unknown
- 2015-06-12 ES ES15734490T patent/ES2706493T3/es active Active
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EA201692548A1 (ru) | 2017-10-31 |
CA2951923A1 (en) | 2015-12-23 |
BR112016029476A2 (pt) | 2017-08-22 |
IL249455A0 (en) | 2017-02-28 |
AU2015277509A1 (en) | 2017-01-05 |
KR20170023061A (ko) | 2017-03-02 |
CN107074884A (zh) | 2017-08-18 |
ES2706493T3 (es) | 2019-03-29 |
WO2015195491A1 (en) | 2015-12-23 |
US9999626B2 (en) | 2018-06-19 |
JP2017526623A (ja) | 2017-09-14 |
EP3157936A1 (en) | 2017-04-26 |
DK3157936T3 (en) | 2019-02-04 |
US20160199385A1 (en) | 2016-07-14 |
EP3157936B1 (en) | 2018-10-17 |
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