MX2016016830A - Complejos de aminoacidos minerales de agentes activos. - Google Patents

Complejos de aminoacidos minerales de agentes activos.

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Publication number
MX2016016830A
MX2016016830A MX2016016830A MX2016016830A MX2016016830A MX 2016016830 A MX2016016830 A MX 2016016830A MX 2016016830 A MX2016016830 A MX 2016016830A MX 2016016830 A MX2016016830 A MX 2016016830A MX 2016016830 A MX2016016830 A MX 2016016830A
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Mexico
Prior art keywords
formula
different
same
fatty acids
application
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Application number
MX2016016830A
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English (en)
Inventor
C Sciavolino Frank
MATHIAS Gary
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Thetis Pharmaceuticals Llc
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Publication date
Application filed by Thetis Pharmaceuticals Llc filed Critical Thetis Pharmaceuticals Llc
Publication of MX2016016830A publication Critical patent/MX2016016830A/es

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    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Public Health (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
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Abstract

La presente invención proporciona compuestos de la Fórmula I y composiciones y métodos relacionados. (ver Fórmula) R1 y R2 cada uno se refiere a una cadena de carbono ramificada o no ramificada desde 1 hasta 20 carbonos que tiene al menos una función básica; R1 y R2 son los mismos o diferentes; X1 y X2 son independientemente seleccionados de H y -CO-Z, donde Z es una porción de péptido que incorpora desde 1 hasta 5 aminoácidos, o una sal farmacéuticamente aceptable de los mismos; X1 y X2 son los mismos o diferentes; M es un catión de metal divalente seleccionado de magnesio (Mg2+), calcio (Ca2+), y zinc (Zn2+); A y B son cada uno una molécula que tiene al menos una función ácida, ya sea A o B, pero no ambos, pueden estar ausentes, y cuando tanto A como B están presentes, A y B pueden ser el mismo o diferente. En una modalidad particular, al menos uno de ``A´´ o ``B´´, o ambos, son ácidos grasos. Un ejemplo representativo de la solicitud es el compuesto Ácido lisinato bis docosapentanoico de magnesio (ver Fórmula) Los complejos de la solicitud se pretenden para composiciones farmacéuticas como aditivos para alimentos, notablemente para tratar afecciones que responden al tratamiento con ácidos grasos poliinsaturados.
MX2016016830A 2014-06-18 2015-06-12 Complejos de aminoacidos minerales de agentes activos. MX2016016830A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462013904P 2014-06-18 2014-06-18
US201462058491P 2014-10-01 2014-10-01
PCT/US2015/035686 WO2015195491A1 (en) 2014-06-18 2015-06-12 Mineral amino-acid complexes of active agents

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MX2016016830A true MX2016016830A (es) 2017-07-07

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MX2016016830A MX2016016830A (es) 2014-06-18 2015-06-12 Complejos de aminoacidos minerales de agentes activos.

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US (1) US9999626B2 (es)
EP (1) EP3157936B1 (es)
JP (1) JP2017526623A (es)
KR (1) KR20170023061A (es)
CN (1) CN107074884A (es)
AU (1) AU2015277509A1 (es)
BR (1) BR112016029476A2 (es)
CA (1) CA2951923A1 (es)
DK (1) DK3157936T3 (es)
EA (1) EA201692548A1 (es)
ES (1) ES2706493T3 (es)
IL (1) IL249455A0 (es)
MX (1) MX2016016830A (es)
WO (1) WO2015195491A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015171516A1 (en) 2014-05-05 2015-11-12 Thetis Pharmaceuticals Llc Compositions and methods relating to ionic salts of peptides
EP3248467A1 (de) * 2016-05-25 2017-11-29 Evonik Technochemie GmbH Verfahren zur herstellung einer zusammensetzung enthaltend omega-3-fettsäure-l-lysin-salze
DK3454907T3 (da) * 2016-06-03 2020-10-19 Thetis Pharmaceuticals Llc Sammensætninger og fremgangsmåder relateret til salte af specialiserede pro-løsningsmediatorer af inflammation
EP3490579A1 (en) * 2016-07-27 2019-06-05 Hartis-Pharma SA Therapeutic combinations to treat red blood cell disorders
EP3275458A1 (en) * 2016-07-27 2018-01-31 Hartis-Pharma Sarl Combination therapy to treat sickle cell disease and restore rbc functions
SE542106C2 (en) 2016-08-26 2020-02-25 Atif M Dabdoub Dietary macro/micronutritional supplement for patients undergoing kidney dialysis
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