ES2593256T3 - Compuestos químicos, composiciones y métodos para las modulaciones de cinasas - Google Patents
Compuestos químicos, composiciones y métodos para las modulaciones de cinasas Download PDFInfo
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- ES2593256T3 ES2593256T3 ES11784354.0T ES11784354T ES2593256T3 ES 2593256 T3 ES2593256 T3 ES 2593256T3 ES 11784354 T ES11784354 T ES 11784354T ES 2593256 T3 ES2593256 T3 ES 2593256T3
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Applications Claiming Priority (3)
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| US34737010P | 2010-05-21 | 2010-05-21 | |
| US347370P | 2010-05-21 | ||
| PCT/US2011/037412 WO2011146882A1 (en) | 2010-05-21 | 2011-05-20 | Chemical compounds, compositions and methods for kinase modulation |
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| ES2593256T3 true ES2593256T3 (es) | 2016-12-07 |
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| ES11784354.0T Active ES2593256T3 (es) | 2010-05-21 | 2011-05-20 | Compuestos químicos, composiciones y métodos para las modulaciones de cinasas |
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| US (3) | US8604032B2 (enExample) |
| EP (1) | EP2571357B1 (enExample) |
| JP (2) | JP5951600B2 (enExample) |
| CN (1) | CN103002738A (enExample) |
| AU (1) | AU2011255218B2 (enExample) |
| CA (1) | CA2799579A1 (enExample) |
| ES (1) | ES2593256T3 (enExample) |
| WO (1) | WO2011146882A1 (enExample) |
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| CN103298474B (zh) | 2010-11-10 | 2016-06-29 | 无限药品股份有限公司 | 杂环化合物及其用途 |
| TWI546305B (zh) | 2011-01-10 | 2016-08-21 | 英菲尼提製藥股份有限公司 | 製備異喹啉酮之方法及異喹啉酮之固體形式 |
| WO2012148548A1 (en) | 2011-02-25 | 2012-11-01 | Takeda Pharmaceutical Company Limited | N-substituted oxazinopteridines and oxazinopteridinones |
| AU2012284088B2 (en) | 2011-07-19 | 2015-10-08 | Infinity Pharmaceuticals Inc. | Heterocyclic compounds and uses thereof |
| WO2013012918A1 (en) | 2011-07-19 | 2013-01-24 | Infinity Pharmaceuticals Inc. | Heterocyclic compounds and uses thereof |
| CA2846431A1 (en) * | 2011-08-29 | 2013-03-07 | Infinity Pharmaceuticals Inc. | Heterocyclic compounds and uses thereof |
| WO2013116562A1 (en) | 2012-02-03 | 2013-08-08 | Gilead Calistoga Llc | Compositions and methods of treating a disease with (s)-4 amino-6-((1-(5-chloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile |
| US8828998B2 (en) * | 2012-06-25 | 2014-09-09 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
| US9029384B2 (en) | 2012-12-21 | 2015-05-12 | Gilead Calistoga, LLC. | Phosphatidylinositol 3-kinase inhibitors |
| US9481667B2 (en) | 2013-03-15 | 2016-11-01 | Infinity Pharmaceuticals, Inc. | Salts and solid forms of isoquinolinones and composition comprising and methods of using the same |
| EP2970194A1 (en) | 2013-03-15 | 2016-01-20 | Infinity Pharmaceuticals, Inc. | Salts and solid forms of isoquinolinones and composition comprising and methods of using the same |
| TWI644909B (zh) | 2013-06-14 | 2018-12-21 | 基利科學股份有限公司 | 磷脂酸肌醇３－激酶抑制劑 |
| UY35675A (es) | 2013-07-24 | 2015-02-27 | Novartis Ag | Derivados sustituidos de quinazolin-4-ona |
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2011
- 2011-05-20 EP EP11784354.0A patent/EP2571357B1/en not_active Not-in-force
- 2011-05-20 ES ES11784354.0T patent/ES2593256T3/es active Active
- 2011-05-20 CA CA2799579A patent/CA2799579A1/en not_active Abandoned
- 2011-05-20 CN CN2011800356311A patent/CN103002738A/zh active Pending
- 2011-05-20 AU AU2011255218A patent/AU2011255218B2/en not_active Ceased
- 2011-05-20 JP JP2013511397A patent/JP5951600B2/ja not_active Expired - Fee Related
- 2011-05-20 US US13/112,611 patent/US8604032B2/en active Active
- 2011-05-20 WO PCT/US2011/037412 patent/WO2011146882A1/en not_active Ceased
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2013
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2015
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2016
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2571357B1 (en) | 2016-07-06 |
| US9738644B2 (en) | 2017-08-22 |
| US20120059000A1 (en) | 2012-03-08 |
| US20140088099A1 (en) | 2014-03-27 |
| CA2799579A1 (en) | 2011-11-24 |
| US8604032B2 (en) | 2013-12-10 |
| US9181221B2 (en) | 2015-11-10 |
| EP2571357A1 (en) | 2013-03-27 |
| JP2013526586A (ja) | 2013-06-24 |
| EP2571357A4 (en) | 2013-11-20 |
| AU2011255218B2 (en) | 2015-03-12 |
| WO2011146882A1 (en) | 2011-11-24 |
| AU2011255218A1 (en) | 2012-12-20 |
| CN103002738A (zh) | 2013-03-27 |
| US20160016957A1 (en) | 2016-01-21 |
| JP5951600B2 (ja) | 2016-07-13 |
| JP2016172744A (ja) | 2016-09-29 |
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