ES2102537T3 - Derivados de glucosaminoglucanos fotoendurecibles, glucosaminoglucanos reticulados y metodo para su produccion. - Google Patents

Derivados de glucosaminoglucanos fotoendurecibles, glucosaminoglucanos reticulados y metodo para su produccion.

Info

Publication number
ES2102537T3
ES2102537T3 ES93101838T ES93101838T ES2102537T3 ES 2102537 T3 ES2102537 T3 ES 2102537T3 ES 93101838 T ES93101838 T ES 93101838T ES 93101838 T ES93101838 T ES 93101838T ES 2102537 T3 ES2102537 T3 ES 2102537T3
Authority
ES
Spain
Prior art keywords
derivatives
photocurable
gag
glycosaminoglycan
crosslinked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93101838T
Other languages
English (en)
Spanish (es)
Inventor
Takehisa Matsuda
Minoo J Moghaddan
Katsukiyo Sakurai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seikagaku Corp
Original Assignee
Seikagaku Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Corp filed Critical Seikagaku Corp
Application granted granted Critical
Publication of ES2102537T3 publication Critical patent/ES2102537T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/042Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06Use of macromolecular materials
    • A61L33/08Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Nanotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biophysics (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES93101838T 1992-02-05 1993-02-05 Derivados de glucosaminoglucanos fotoendurecibles, glucosaminoglucanos reticulados y metodo para su produccion. Expired - Lifetime ES2102537T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP4774492 1992-02-05
JP20320992 1992-07-08
JP4355441A JP2855307B2 (ja) 1992-02-05 1992-12-21 光反応性グリコサミノグリカン、架橋グリコサミノグリカン及びそれらの製造方法

Publications (1)

Publication Number Publication Date
ES2102537T3 true ES2102537T3 (es) 1997-08-01

Family

ID=27293072

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93101838T Expired - Lifetime ES2102537T3 (es) 1992-02-05 1993-02-05 Derivados de glucosaminoglucanos fotoendurecibles, glucosaminoglucanos reticulados y metodo para su produccion.

Country Status (14)

Country Link
US (2) US5462976A (cg-RX-API-DMAC7.html)
EP (1) EP0554898B1 (cg-RX-API-DMAC7.html)
JP (1) JP2855307B2 (cg-RX-API-DMAC7.html)
KR (1) KR100293043B1 (cg-RX-API-DMAC7.html)
CN (1) CN1083455C (cg-RX-API-DMAC7.html)
AT (1) ATE152736T1 (cg-RX-API-DMAC7.html)
AU (1) AU670921B2 (cg-RX-API-DMAC7.html)
CA (1) CA2088831C (cg-RX-API-DMAC7.html)
DE (1) DE69310396T2 (cg-RX-API-DMAC7.html)
DK (1) DK0554898T3 (cg-RX-API-DMAC7.html)
ES (1) ES2102537T3 (cg-RX-API-DMAC7.html)
HU (1) HU215503B (cg-RX-API-DMAC7.html)
RU (1) RU2139886C1 (cg-RX-API-DMAC7.html)
TW (1) TW222644B (cg-RX-API-DMAC7.html)

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824335A (en) * 1991-12-18 1998-10-20 Dorigatti; Franco Non-woven fabric material comprising auto-crosslinked hyaluronic acid derivatives
JPH07250887A (ja) * 1994-03-15 1995-10-03 Seikagaku Kogyo Co Ltd 人工血管およびその製造方法
JP3563440B2 (ja) * 1994-05-16 2004-09-08 生化学工業株式会社 アシル化ヒアルロン酸の製造法
JP3343181B2 (ja) * 1995-09-20 2002-11-11 生化学工業株式会社 桂皮酸誘導体
CA2162957C (en) * 1994-11-17 2011-08-02 Michinori Waki Cinnamic acid derivative
US6025444A (en) * 1994-11-17 2000-02-15 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Cinnamic acid derivative
JP3308742B2 (ja) * 1994-11-17 2002-07-29 生化学工業株式会社 光架橋性ヒアルロン酸誘導体とその架橋体およびそれらの製造方法
US6129956A (en) * 1995-02-07 2000-10-10 Fidia Advanced Bioplymers, Srl Process for the coating of objects with hyaluronic acid, derivatives thereof, and semisynthetic polymers
PT813546E (pt) * 1995-03-07 2002-11-29 Novartis Ag Derivados de polissacarideos contendo ligacoes cruzadas por fotoquimica como suporte para a separacao cromatografica de enantiomeros
JP3955107B2 (ja) * 1995-05-01 2007-08-08 生化学工業株式会社 架橋多糖の製造法
TW362100B (en) * 1995-07-21 1999-06-21 Novartis Ag The preparation and use of photochemically cross-linked polysaccharide derivatives having no photopolymerisable functional groups
BR9610996A (pt) * 1995-08-29 1999-07-13 Fidia Advanced Biopolymers Srl Biomateriais para prevenção de ades es pós-cirúrgicas compreendendo derivados de ácidos hialurônico
US5789462A (en) * 1995-09-13 1998-08-04 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Photocured crosslinked-hyaluronic acid contact lens
CA2237192C (en) * 1995-11-15 2006-06-20 Seikagaku Corporation Photocured crosslinked-hyaluronic acid gel and method of preparation thereof
JP3136352B2 (ja) * 1996-01-22 2001-02-19 参天製薬株式会社 角結膜疾患治療剤
US5922690A (en) * 1996-04-25 1999-07-13 Van Gorp; Cornelius L. Dermatan disulfate, an inhibitor of thrombin generation and activation
JP4317599B2 (ja) * 1996-06-26 2009-08-19 武田薬品工業株式会社 徐放性製剤
WO1998016559A1 (fr) * 1996-10-15 1998-04-23 Toray Industries, Inc. Agent de maturation des canaux cervicaux
DK0971961T3 (da) * 1997-04-04 2003-03-24 Fidia Advanced Biopolymers Srl N-sulfaterede hyaluronsyreforbindelser, derivater deraf og en fremgangsmåde til deres fremstilling
DE19729279A1 (de) * 1997-07-09 1999-01-14 Peter Hildebrandt Urologisches Implantat, insbesondere Gefäßwandstütze für den Urinaltrakt
US5945457A (en) * 1997-10-01 1999-08-31 A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science Process for preparing biologically compatible polymers and their use in medical devices
GB9722604D0 (en) * 1997-10-28 1997-12-24 Cancer Res Campaign Tech Heparin-binding growth factor derivatives
ITPD980169A1 (it) * 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
US6632457B1 (en) * 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US6818018B1 (en) 1998-08-14 2004-11-16 Incept Llc In situ polymerizable hydrogels
US6514534B1 (en) 1998-08-14 2003-02-04 Incept Llc Methods for forming regional tissue adherent barriers and drug delivery systems
US6630457B1 (en) * 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
JP4406943B2 (ja) * 1998-10-22 2010-02-03 生化学工業株式会社 紫外線照射装置および光架橋グリコサミノグリカンの製造方法
IT1303738B1 (it) * 1998-11-11 2001-02-23 Aquisitio S P A Processo di reticolazione di polisaccaridi carbossilati.
US6409987B1 (en) 1999-04-07 2002-06-25 Intimax Corporation Targeted agents useful for diagnostic and therapeutic applications
US6596474B1 (en) 1999-07-01 2003-07-22 Scios Inc. Prevention and treatment of amyloid-associated disorders
US6518244B2 (en) 2000-03-09 2003-02-11 Intimax Corporation Combinations of heparin cofactor II agonist and platelet IIb/IIIa antagonist, and uses thereof
FR2808271A1 (fr) * 2000-04-27 2001-11-02 Oreal Nouveaux derives d'aminoacides, leur procede de preparation, compositions les contenant et leurs utilisations comme filtres solaires
JP2001329002A (ja) * 2000-05-25 2001-11-27 Denki Kagaku Kogyo Kk 修飾ヒアルロン酸ゲルとその製造方法及びそれを含有する医用材料
EP1188773A1 (en) * 2000-08-30 2002-03-20 Nicox S.A. Nitroderivatives of polysaccharides
JP4172176B2 (ja) * 2000-12-19 2008-10-29 生化学工業株式会社 光反応性ヒアルロン酸およびその製造方法ならびに光架橋ヒアルロン酸および医用材料
DE60117502T2 (de) * 2000-12-19 2006-08-24 Seikagaku Corp. Photohärtbare Derivate von Hyaluronsäure, Verfahren zu deren Herstellung, vernetztes und photogehärtetes Derivat der Hyaluronsäure und diese enthaltendes medizinisches Material
WO2002060971A1 (fr) * 2001-01-31 2002-08-08 Seikagaku Corporation Eponge polysaccharidique reticulee
US6586493B1 (en) 2001-03-07 2003-07-01 Arizona Board Of Regents Arizona State University Polysaccharide-based hydrogels and pre-gel blends for the same
AU2002258490A1 (en) * 2001-03-12 2003-06-17 Clemson University Polysaccharide-based polmerizable hydrogels
US6610810B2 (en) 2001-03-13 2003-08-26 Glyn Owen Phillips Biopolymers obtained by solid state irradiation in an unsaturated gaseous atmosphere
US6673919B2 (en) * 2001-03-30 2004-01-06 Chisso Cororation Chemically modified hyaluronic acid or salts thereof, and a process for producing thereof
EP1249247B1 (en) * 2001-03-30 2007-02-28 Chisso Corporation Pharmaceutical preparation for the treatment of gynecological diseases
US7157458B2 (en) 2001-04-17 2007-01-02 Cryolife, Inc. Bifunctional energy-reversible acyl-compositions
US7923055B2 (en) * 2001-05-11 2011-04-12 Exogenesis Corporation Method of manufacturing a drug delivery system
US7666462B2 (en) * 2001-05-11 2010-02-23 Exogenesis Corporation Method of controlling a drug release rate
US8889169B2 (en) * 2001-05-11 2014-11-18 Exogenesis Corporation Drug delivery system and method of manufacturing thereof
US6844028B2 (en) 2001-06-26 2005-01-18 Accelr8 Technology Corporation Functional surface coating
US7501157B2 (en) 2001-06-26 2009-03-10 Accelr8 Technology Corporation Hydroxyl functional surface coating
US8101196B2 (en) * 2001-06-26 2012-01-24 Biointeractions, Ltd. Polysaccharide biomaterials and methods of use thereof
JP3947391B2 (ja) * 2001-11-28 2007-07-18 独立行政法人 日本原子力研究開発機構 橋かけ構造を有するキチン誘導体及び/又はキトサン誘導体の製造方法
JP2003190259A (ja) * 2001-12-28 2003-07-08 Hisako Ogawara 人工臓器用チャンバー
ITPD20020064A1 (it) 2002-03-12 2003-09-12 Fidia Advanced Biopolymers Srl Derivati esterei dell'acido ialuronico per la preparazione di idrogelda utilizzare in campo biomedico, sanitario e chirurgico e come sistem
JP4340423B2 (ja) * 2002-06-20 2009-10-07 生化学工業株式会社 光反応性糖化合物および標識化光反応性糖化合物ならびに糖受容体の捕捉および測定方法
RU2233653C2 (ru) * 2002-09-24 2004-08-10 Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" им. акад. С.Н. Федорова Раствор и способ изготовления на его основе геля для формирования опорно-двигательной культи и устранения дефицита тканей орбиты
AU2003288911B8 (en) * 2002-09-25 2009-12-24 Johns Hopkins University Cross-linked polymer matrices, and methods of making and using same
US8673333B2 (en) * 2002-09-25 2014-03-18 The Johns Hopkins University Cross-linked polymer matrices, and methods of making and using same
RU2249467C2 (ru) * 2002-11-25 2005-04-10 ООО Научно-производственное предприятие "ЭРЛОН", Лтд. Медицинский материал и изделия на его основе
RU2223793C1 (ru) * 2002-12-10 2004-02-20 Естественно-научный институт при Пермском государственном университете Способ приготовления лекарствовыделяющего материала
JP4813179B2 (ja) * 2003-03-11 2011-11-09 生化学工業株式会社 光架橋多糖組成物およびその製造方法
AU2004251040A1 (en) * 2003-05-15 2005-01-06 University Of Utah Research Foundation Anti-adhesion composites and methods os use thereof
JP2005073606A (ja) * 2003-09-01 2005-03-24 Seikagaku Kogyo Co Ltd 培養基材
CN100486999C (zh) * 2003-09-12 2009-05-13 生化学工业株式会社 多糖假海绵
US7225024B2 (en) * 2003-09-30 2007-05-29 Cardiac Pacemakers, Inc. Sensors having protective eluting coating and method therefor
US8313765B2 (en) * 2003-12-04 2012-11-20 Industrial Technology Research Institute Biodegradable hyaluronic acid derivative, biodegradable polymeric micelle composition and pharmaceutical or bioactive composition
GB2408741B (en) * 2003-12-04 2008-06-18 Ind Tech Res Inst Hyaluronic acid derivative with urethane linkage
CA2565818C (en) * 2004-05-07 2013-07-30 Seikagaku Corporation Nucleus pulposus filler comprising crosslinked chondroitin sulfate
US7604830B2 (en) * 2004-06-24 2009-10-20 Cook Incorporated Method and apparatus for coating interior surfaces of medical devices
JP4523812B2 (ja) * 2004-07-02 2010-08-11 生化学工業株式会社 胚性幹細胞の培養用基材及びその用途
JP2006076968A (ja) * 2004-09-10 2006-03-23 Seikagaku Kogyo Co Ltd 生理活性分子含有架橋ヘパリンゲル組成物
WO2006030965A1 (en) * 2004-09-15 2006-03-23 Seikagaku Corporation Photoreactive polysaccharide, photocrosslinked polysaccharide products, the method of making them and medical materials therefrom
US20060069063A1 (en) * 2004-09-27 2006-03-30 Yng-Jiin Wang Crosslinked polygalacturonic acid used for postsurgical tissue adhesion prevention
US8754179B2 (en) * 2004-10-06 2014-06-17 Cornerstone Research Group, Inc. Light activated shape memory co-polymers
ITPD20040265A1 (it) * 2004-10-27 2005-01-27 Fidia Advanced Biopolymers Srl Innesti vascolari costituiti da derivati dell'acido ialuronico in forma tubulare
WO2006089119A2 (en) * 2005-02-18 2006-08-24 Cartilix, Inc. Biological adhesive
ITPD20050056A1 (it) 2005-03-02 2006-09-03 Fidia Farmaceutici Derivati ammidici del'acido ialuronico in osteoartrosi
WO2007004675A1 (ja) * 2005-07-06 2007-01-11 Seikagaku Corporation 薬剤導入光架橋ヒアルロン酸誘導体ゲル
CN103120701B (zh) * 2005-10-12 2014-11-05 生化学工业株式会社 包含疏水基团结合型糖胺聚糖在制备预防或治疗角膜上皮层病症的药物中的用途
AU2012201314B2 (en) * 2005-10-12 2014-04-10 Seikagaku Corporation Agent for applying to mucosa and method for production thereof
CA2634245C (en) * 2005-12-28 2013-12-10 Dentsply International Inc. Light-curable bone growth material for treating dental bone defects
TWI528964B (zh) * 2006-12-06 2016-04-11 生化學工業股份有限公司 治療關節失調之長效藥劑
TWI320180B (en) 2007-01-12 2010-02-01 A driving method and a driving system for writing the phase change memory
JP2007146178A (ja) * 2007-02-01 2007-06-14 Seikagaku Kogyo Co Ltd キトサン誘導体及び架橋キトサン
WO2008136536A1 (ja) * 2007-05-01 2008-11-13 National University Corporation Tokyo Medical And Dental University 化学架橋ヒアルロン酸誘導体を含むハイブリッドゲルおよびそれを用いた医薬組成物
EP2095832A1 (de) 2008-02-28 2009-09-02 Bayer MaterialScience AG Polyharnstoff-Systeme und deren Anwendung als postoperative Adhäsionsbarrieren, Filme und Verbundteile.
KR101078302B1 (ko) * 2008-05-29 2011-10-31 (주)프로넥스 약물전달체
US20100036482A1 (en) * 2008-08-07 2010-02-11 Exogenesis Corporation Drug delivery system and method of manufacturing thereof
JP5878369B2 (ja) 2008-08-07 2016-03-08 エクソジェネシス コーポレーション 骨インプラントのための医療機器およびその機器の製造方法
US8409606B2 (en) 2009-02-12 2013-04-02 Incept, Llc Drug delivery through hydrogel plugs
JO3008B1 (ar) * 2009-08-13 2016-09-05 Seikagaku Kogyo Co Ltd تركيب صيدلي لتخفيف الألم
AU2010314994B2 (en) 2009-11-09 2016-10-06 Spotlight Technology Partners Llc Fragmented hydrogels
US9700650B2 (en) 2009-11-09 2017-07-11 Spotlight Technology Partners Llc Polysaccharide based hydrogels
CZ302504B6 (cs) 2009-12-11 2011-06-22 Contipro C A.S. Derivát kyseliny hyaluronové oxidovaný v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd, zpusob jeho prípravy a zpusob jeho modifikace
CZ302503B6 (cs) 2009-12-11 2011-06-22 Contipro C A.S. Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace
CN101831006B (zh) * 2010-05-21 2012-01-18 常州大学 一种新型含香豆素荧光基团透明质酸衍生物的制备方法
EP2585586B1 (en) * 2010-06-22 2017-03-22 Universite de Rouen Improved crosslinked hyaluronan hydrogels for 3d cell culture
ITTO20110428A1 (it) 2011-05-13 2012-11-14 Rottapharm Spa Esteri dell'acido ialuronico, loro preparazione ed uso in dermatologia
US9567357B2 (en) 2011-06-24 2017-02-14 Biointeractions Ltd. Biocompatible, biomimetic ampholyte materials
JP5263349B2 (ja) * 2011-08-08 2013-08-14 生化学工業株式会社 生理活性分子含有架橋ヘパリンゲル組成物
TWI561535B (en) 2011-10-06 2016-12-11 Bvw Holding Ag Copolymers of hydrophobic and hydrophilic segments that reduce protein adsorption
EP2612846A1 (de) 2012-01-09 2013-07-10 Bayer MaterialScience AG Beta-Aminosäureester und deren Verwendung
CZ303879B6 (cs) 2012-02-28 2013-06-05 Contipro Biotech S.R.O. Deriváty na bázi kyseliny hyaluronové schopné tvorit hydrogely, zpusob jejich prípravy, hydrogely na bázi techto derivátu, zpusob jejich prípravy a pouzití
CZ304512B6 (cs) 2012-08-08 2014-06-11 Contipro Biotech S.R.O. Derivát kyseliny hyaluronové, způsob jeho přípravy, způsob jeho modifikace a použití
CZ2012844A3 (cs) * 2012-11-27 2014-02-05 Contipro Biotech S.R.O. Fotoreaktivní derivát kyseliny hyaluronové, způsob jeho přípravy, 3D síťovaný derivát kyseliny hyaluronové, způsob jeho přípravy a použití
CZ2012842A3 (cs) 2012-11-27 2014-08-20 Contipro Biotech S.R.O. Nanomicelární kompozice na bázi C6-C18-acylovaného hyaluronanu, způsob přípravy C6-C18-acylovaného hyaluronanu, způsob přípravy nanomicelární kompozice a stabilizované nanomicelární kompozice a použití
ITMI20130162A1 (it) 2013-02-06 2014-08-07 Fidia Farmaceutici Derivati fotoreticolati di acido ialuronico, loro processo di preparazione ed impiego
USRE49528E1 (en) 2013-04-26 2023-05-16 Biointeractions Ltd. Bioactive coatings
AU2014259261B2 (en) 2013-04-26 2018-06-07 Biointeractions Limited Bioactive coatings
GB2518405A (en) * 2013-09-20 2015-03-25 Zeiss Carl Meditec Ag Composition comprising at least one viscoelastic polymer
CZ2013914A3 (cs) * 2013-11-21 2015-02-25 Contipro Biotech S.R.O. Nanovlákna obsahující fototvrditelný esterový derivát kyseliny hyaluronové nebo její soli, fototvrzená nanovlákna, způsob jejich syntézy, přípravek obsahující fototvrzená nanovlákna a jejich použití
US10294195B2 (en) 2014-01-31 2019-05-21 Seikagaku Corporation Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials
CZ2014150A3 (cs) 2014-03-11 2015-05-20 Contipro Biotech S.R.O. Konjugáty oligomeru kyseliny hyaluronové nebo její soli, způsob jejich přípravy a použití
CZ2014451A3 (cs) 2014-06-30 2016-01-13 Contipro Pharma A.S. Protinádorová kompozice na bázi kyseliny hyaluronové a anorganických nanočástic, způsob její přípravy a použití
EP3246037A4 (en) 2015-01-16 2018-07-11 Seikagaku Corporation Crosslinked chondroitin sulfate, composition containing same, and treatment agent for eye disease
CZ309295B6 (cs) 2015-03-09 2022-08-10 Contipro A.S. Samonosný, biodegradabilní film na bázi hydrofobizované kyseliny hyaluronové, způsob jeho přípravy a použití
JP6887377B2 (ja) * 2015-05-29 2021-06-16 生化学工業株式会社 グリコサミノグリカン誘導体とケモカイン受容体活性調節材とを含む組成物
CZ306479B6 (cs) 2015-06-15 2017-02-08 Contipro A.S. Způsob síťování polysacharidů s využitím fotolabilních chránicích skupin
CZ306662B6 (cs) 2015-06-26 2017-04-26 Contipro A.S. Deriváty sulfatovaných polysacharidů, způsob jejich přípravy, způsob jejich modifikace a použití
WO2017030184A1 (ja) * 2015-08-20 2017-02-23 生化学工業株式会社 眼用デバイス適用剤
EP4279537A3 (en) * 2015-12-29 2024-02-21 Galderma S.A. Carbohydrate crosslinker
CZ308106B6 (cs) 2016-06-27 2020-01-08 Contipro A.S. Nenasycené deriváty polysacharidů, způsob jejich přípravy a jejich použití
CZ307158B6 (cs) * 2016-12-23 2018-02-07 Contipro A.S. Oftalmologický prostředek
US11732060B2 (en) 2019-01-30 2023-08-22 Bausch & Lomb Incorporated Crosslinked polymeric network and use thereof
KR102240726B1 (ko) * 2019-01-31 2021-04-16 주식회사 에스엔비아 방사성 동위원소가 표지된 광가교성 하이드로젤 및 그 제조 방법
CA3188951A1 (en) * 2020-08-14 2022-02-17 The University Of Tokyo Polysaccharide derivative, polysaccharide derivative-drug conjugate, and method for producing same
CN113230464B (zh) * 2021-04-01 2022-04-12 暨南大学 一种抗再狭窄3d打印自扩张可降解血管支架及其制备方法
DE102021212812A1 (de) 2021-11-15 2023-05-17 Bauerfeind Ag Entzündungshemmendes viskosupplementierendes Mittel enthaltend Hyaluronsäure

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2349948A1 (de) * 1972-10-06 1974-05-02 Agency Ind Science Techn Neue photopolymere
US3960685A (en) * 1973-11-12 1976-06-01 Sumitomo Chemical Company, Limited Photosensitive resin composition containing pullulan or esters thereof
US4141973A (en) * 1975-10-17 1979-02-27 Biotrics, Inc. Ultrapure hyaluronic acid and the use thereof
JPS54128482A (en) * 1978-03-29 1979-10-05 Agency Of Ind Science & Technol Microcapsule and its preparation
JPS5647439A (en) * 1979-09-26 1981-04-30 Japan Synthetic Rubber Co Ltd Photosetting material
US4331697A (en) * 1980-09-02 1982-05-25 Teijin Limited Novel heparin derivative, method for production thereof, and method for rendering biomedical materials antithrombotic by use of the novel heparin derivative
JPS5789751A (en) * 1980-11-25 1982-06-04 Japan Synthetic Rubber Co Ltd Photosensitive material
JPS5789752A (en) * 1980-11-25 1982-06-04 Japan Synthetic Rubber Co Ltd Photosensitive material
US4722906A (en) * 1982-09-29 1988-02-02 Bio-Metric Systems, Inc. Binding reagents and methods
US4973493A (en) * 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
US5217492A (en) * 1982-09-29 1993-06-08 Bio-Metric Systems, Inc. Biomolecule attachment to hydrophobic surfaces
US5002582A (en) * 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
US4745098A (en) * 1984-02-24 1988-05-17 The Regents Of The University Of California Compositions and method for improving wound healing
JPH0699482B2 (ja) * 1984-04-16 1994-12-07 ダイセル化学工業株式会社 多糖類誘導体
US4716224A (en) * 1984-05-04 1987-12-29 Seikagaku Kogyo Co. Ltd. Crosslinked hyaluronic acid and its use
SE442820B (sv) * 1984-06-08 1986-02-03 Pharmacia Ab Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut
JPS6016260A (ja) * 1984-06-18 1985-01-28 Hitachi Ltd ヒ−トポンプ式風呂加熱機
US4863907A (en) * 1984-06-29 1989-09-05 Seikagaku Kogyo Co., Ltd. Crosslinked glycosaminoglycans and their use
SE456346B (sv) * 1984-07-23 1988-09-26 Pharmacia Ab Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning
US5128326A (en) * 1984-12-06 1992-07-07 Biomatrix, Inc. Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same
US4979959A (en) * 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
JPS6439569A (en) * 1987-08-05 1989-02-09 Sumitomo Electric Industries Optical magnetic field sensor
JP2606890B2 (ja) * 1988-07-26 1997-05-07 富士通株式会社 半導体チップのピックアップ方法
SE8900586L (sv) * 1989-02-21 1990-08-22 Pharmacia Ab Komposition och foerfarande foer att foerhindra adhesion mellan kroppsvaevnader
DE3912122A1 (de) * 1989-04-13 1990-10-25 Wella Ag Uv-strahlen absorbierende chitosan- und chitinderivate, verfahren zu deren herstellung und diese verbindungen enthaltendes kosmetisches mittel
US5356883A (en) * 1989-08-01 1994-10-18 Research Foundation Of State University Of N.Y. Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
JP2877423B2 (ja) * 1990-03-13 1999-03-31 積水化学工業株式会社 口腔内貼付用バンデージ
US5246698A (en) * 1990-07-09 1993-09-21 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
US5143724A (en) * 1990-07-09 1992-09-01 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use

Also Published As

Publication number Publication date
JP2855307B2 (ja) 1999-02-10
HU215503B (hu) 1999-01-28
EP0554898B1 (en) 1997-05-07
HU9300297D0 (en) 1993-04-28
RU2139886C1 (ru) 1999-10-20
CA2088831C (en) 2004-07-06
CN1083455C (zh) 2002-04-24
KR100293043B1 (ko) 2001-10-22
DE69310396D1 (de) 1997-06-12
EP0554898A3 (cg-RX-API-DMAC7.html) 1994-01-26
US5763504A (en) 1998-06-09
AU670921B2 (en) 1996-08-08
DK0554898T3 (da) 1997-12-01
AU3287893A (en) 1993-08-12
KR930017921A (ko) 1993-09-20
CA2088831A1 (en) 1993-08-06
HUT71625A (en) 1996-01-29
CN1075970A (zh) 1993-09-08
TW222644B (cg-RX-API-DMAC7.html) 1994-04-21
US5462976A (en) 1995-10-31
EP0554898A2 (en) 1993-08-11
DE69310396T2 (de) 1997-10-16
JPH0673102A (ja) 1994-03-15
ATE152736T1 (de) 1997-05-15

Similar Documents

Publication Publication Date Title
ES2102537T3 (es) Derivados de glucosaminoglucanos fotoendurecibles, glucosaminoglucanos reticulados y metodo para su produccion.
RU93004491A (ru) Фотоотверждаемые производные гликозаминогликана, сшитые гликозаминогликаны и способы их получения, материал для медицинского использования, применение, способ предотвращения клеточной и тканевой адгезии
DE68916707D1 (de) Verfahren zur Herstellung eines hydrophilen Polymers.
DE59108100D1 (de) Verfahren zur Herstellung eines Olefinpolymers
NO982212D0 (no) Fotoherdet fornettet hyaluronsyre-gel og fremgangsmÕte for fremstilling derav
DE68913226D1 (de) Verfahren zur Herstellung von Ethylenpolymeren.
DE68908490D1 (de) Verfahren zur herstellung eines wasser absorbierenden polymers.
DE59209181D1 (de) Verfahren zur Herstellung von Mikrostrukturkörpern
ATE141929T1 (de) Verfahren zur herstellung von epoxy-hepariden; die so hergestellten produkte und diese enthaltende pharmazeutische zusammensetzungen
AT376441B (de) Verfahren zur herstellung von isocyanuratgruppen aufweisenden kunststoffen
BR8807660A (pt) Composto, processo para preparacao de um homo-ou um copolimero, produto de homo-ou copolimero estabilizado, processo para a preparacao de um poliester curado e produto poliester curado
ZW21279A1 (en) Photopolymerisable compositions
DE68923534D1 (de) Verfahren zur Herstellung eines organischen Kristalls.
BR8702013A (pt) Processo de preparacao de compostos carbonilados etilenicos
DE69406814D1 (de) Verfahren zur Herstellung resorbierbarem Polymer
DE68911435D1 (de) Verfahren zur Herstellung eines Polymers.
DE3866166D1 (de) Verfahren zur herstellung eines ethylenpolymers.
ATE132353T1 (de) Polymerprodukte
ATE81495T1 (de) Verfahren zur herstellung von natriumfluoralkoholaten.
IT1123024B (it) Procedimento per produrre tricloruro di titanio quale componente di catalizzatore e prodotto ottenuto da esso
EP0687694A3 (de) Verfahren zur Herstellung von Polymerisaten auf Basis von 1-Vinylimidazolen
DE68911323D1 (de) Verfahren zur Herstellung eines Elektrokatalysators.
BR8000588A (pt) Processo para preparacao de uma fibra de polimero de acrilo-nitrila
DK156690A (da) Fremgangsmaade til specifik syntese af dithiocarbaminsyreestere ved substitution af hydroxylerede positioner paa mono- eller polyhydroxylerede molekyler, produkter opnaaet ved fremgangsmaaden og anvendelse af saadanne
SU808331A1 (ru) Способ изготовлени плит изВиНОгРАдНОй лОзы

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 554898

Country of ref document: ES