DK1196444T3 - Exendin-4-konjugater og deres medicinske anvendelighed - Google Patents

Exendin-4-konjugater og deres medicinske anvendelighed

Info

Publication number
DK1196444T3
DK1196444T3 DK00945656T DK00945656T DK1196444T3 DK 1196444 T3 DK1196444 T3 DK 1196444T3 DK 00945656 T DK00945656 T DK 00945656T DK 00945656 T DK00945656 T DK 00945656T DK 1196444 T3 DK1196444 T3 DK 1196444T3
Authority
DK
Denmark
Prior art keywords
conjugates
exendin
medical utility
medical
utility
Prior art date
Application number
DK00945656T
Other languages
Danish (da)
English (en)
Inventor
Jens Damsgaard Mikkelsen
Bjarne Due Larsen
Soren Neve
Original Assignee
Zealand Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zealand Pharma As filed Critical Zealand Pharma As
Application granted granted Critical
Publication of DK1196444T3 publication Critical patent/DK1196444T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DK00945656T 1999-07-12 2000-07-12 Exendin-4-konjugater og deres medicinske anvendelighed DK1196444T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14359199P 1999-07-12 1999-07-12
EP99610043A EP1076066A1 (de) 1999-07-12 1999-08-09 Peptide zur Senkung des Blutglukosespiegels
PCT/DK2000/000393 WO2001004156A1 (en) 1999-07-12 2000-07-12 Peptides that lower blood glucose levels

Publications (1)

Publication Number Publication Date
DK1196444T3 true DK1196444T3 (da) 2003-09-29

Family

ID=26153727

Family Applications (3)

Application Number Title Priority Date Filing Date
DK09002937.2T DK2112161T3 (en) 1999-07-12 2000-07-12 Peptides that lower blood glucose levels
DK00945656T DK1196444T3 (da) 1999-07-12 2000-07-12 Exendin-4-konjugater og deres medicinske anvendelighed
DK03005786.3T DK1329458T5 (da) 1999-07-12 2000-07-12 Peptider som sænker blodglucoseniveauer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK09002937.2T DK2112161T3 (en) 1999-07-12 2000-07-12 Peptides that lower blood glucose levels

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK03005786.3T DK1329458T5 (da) 1999-07-12 2000-07-12 Peptider som sænker blodglucoseniveauer

Country Status (20)

Country Link
US (1) US20070111940A1 (de)
EP (4) EP1076066A1 (de)
JP (4) JP4332314B2 (de)
CN (1) CN1229390C (de)
AT (2) ATE242267T1 (de)
AU (2) AU781338B2 (de)
BE (1) BE2013C033I2 (de)
CA (2) CA2378431C (de)
CY (2) CY1113347T1 (de)
DE (1) DE60003182T2 (de)
DK (3) DK2112161T3 (de)
ES (3) ES2384963T3 (de)
FR (1) FR13C0021I2 (de)
HK (2) HK1058046A1 (de)
IL (4) IL147293A0 (de)
LU (1) LU92175I2 (de)
NZ (1) NZ517012A (de)
PT (3) PT2112161E (de)
SI (2) SI1329458T1 (de)
WO (1) WO2001004156A1 (de)

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IL206445A (en) 2011-09-27
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CA2378431A1 (en) 2001-01-18
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