DE60002172T2 - Verwendung von (1r,4s)-4-(6-amino-9h-purin-9-yl)-2-cyclopenten-1-methanol in hbv - Google Patents

Verwendung von (1r,4s)-4-(6-amino-9h-purin-9-yl)-2-cyclopenten-1-methanol in hbv

Info

Publication number
DE60002172T2
DE60002172T2 DE60002172T DE60002172T DE60002172T2 DE 60002172 T2 DE60002172 T2 DE 60002172T2 DE 60002172 T DE60002172 T DE 60002172T DE 60002172 T DE60002172 T DE 60002172T DE 60002172 T2 DE60002172 T2 DE 60002172T2
Authority
DE
Germany
Prior art keywords
purin
methanol
amino
cyclopenten
hbv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60002172T
Other languages
English (en)
Other versions
DE60002172D1 (de
Inventor
Susan Mary Daluge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE60002172D1 publication Critical patent/DE60002172D1/de
Publication of DE60002172T2 publication Critical patent/DE60002172T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE60002172T 1999-02-12 2000-02-11 Verwendung von (1r,4s)-4-(6-amino-9h-purin-9-yl)-2-cyclopenten-1-methanol in hbv Expired - Lifetime DE60002172T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9903091.8A GB9903091D0 (en) 1999-02-12 1999-02-12 Therapeutic nucleoside compound
PCT/GB2000/000429 WO2000047581A1 (en) 1999-02-12 2000-02-11 Therapeutic nucleoside compound

Publications (2)

Publication Number Publication Date
DE60002172D1 DE60002172D1 (de) 2003-05-22
DE60002172T2 true DE60002172T2 (de) 2003-11-27

Family

ID=10847550

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60002172T Expired - Lifetime DE60002172T2 (de) 1999-02-12 2000-02-11 Verwendung von (1r,4s)-4-(6-amino-9h-purin-9-yl)-2-cyclopenten-1-methanol in hbv

Country Status (14)

Country Link
US (1) US6630477B1 (de)
EP (1) EP1150981B1 (de)
JP (1) JP2002536448A (de)
KR (1) KR20010102081A (de)
CN (1) CN1346356A (de)
AT (1) ATE237616T1 (de)
AU (1) AU2450900A (de)
DE (1) DE60002172T2 (de)
DK (1) DK1150981T3 (de)
ES (1) ES2195861T3 (de)
GB (1) GB9903091D0 (de)
HK (1) HK1039935B (de)
PT (1) PT1150981E (de)
WO (1) WO2000047581A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2368580A1 (de) * 2006-06-21 2011-09-28 Ge Healthcare As Stabilisierung von Fluorthymidinvorläufern
US11583497B2 (en) 2017-11-14 2023-02-21 The Schepens Eye Research Institute, Inc. Nano-emulsion of CBFß-RUNX1 inhibitor for ocular drug delivery

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916224A (en) 1988-01-20 1990-04-10 Regents Of The University Of Minnesota Dideoxycarbocyclic nucleosides
CA1339896C (en) * 1988-01-20 1998-06-02 Robert Vince Dideoxydidehydrocarbocyclic nucleosides
NZ229453A (en) * 1988-06-10 1991-08-27 Univ Minnesota & Southern Rese A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
GB8815265D0 (en) 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
DE68907013D1 (de) * 1988-10-24 1993-07-15 Wellcome Found Guaninderivate mit antiviraler wirkung und deren pharmazeutisch vertraegliche salze.
MY104575A (en) 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
EP0468119A1 (de) * 1990-07-24 1992-01-29 Merrell Dow Pharmaceuticals Inc. Neue Carbocyclische Analoge einiger Nukleoside
JPH06199812A (ja) * 1991-02-12 1994-07-19 Takeda Chem Ind Ltd 新規シクロペンテン誘導体
GB9417249D0 (en) 1994-08-26 1994-10-19 Wellcome Found A novel salt

Also Published As

Publication number Publication date
CN1346356A (zh) 2002-04-24
PT1150981E (pt) 2003-08-29
ATE237616T1 (de) 2003-05-15
WO2000047581A1 (en) 2000-08-17
ES2195861T3 (es) 2003-12-16
KR20010102081A (ko) 2001-11-15
EP1150981B1 (de) 2003-04-16
EP1150981A1 (de) 2001-11-07
HK1039935A1 (en) 2002-05-17
HK1039935B (zh) 2003-12-19
DE60002172D1 (de) 2003-05-22
JP2002536448A (ja) 2002-10-29
DK1150981T3 (da) 2003-07-21
US6630477B1 (en) 2003-10-07
AU2450900A (en) 2000-08-29
GB9903091D0 (en) 1999-03-31

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