PL2324853T3 - Liksysenatyd jako dodatek do metforminy w leczeniu cukrzycy typu 2 - Google Patents
Liksysenatyd jako dodatek do metforminy w leczeniu cukrzycy typu 2Info
- Publication number
- PL2324853T3 PL2324853T3 PL09175876T PL09175876T PL2324853T3 PL 2324853 T3 PL2324853 T3 PL 2324853T3 PL 09175876 T PL09175876 T PL 09175876T PL 09175876 T PL09175876 T PL 09175876T PL 2324853 T3 PL2324853 T3 PL 2324853T3
- Authority
- PL
- Poland
- Prior art keywords
- lixisenatide
- metformin
- add
- treatment
- diabetes type
- Prior art date
Links
- XVVOERDUTLJJHN-UHFFFAOYSA-N Lixisenatide Chemical compound C=1NC2=CC=CC=C2C=1CC(C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(N)=O)C(=O)NCC(=O)NCC(=O)N1C(CCC1)C(=O)NC(CO)C(=O)NC(CO)C(=O)NCC(=O)NC(C)C(=O)N1C(CCC1)C(=O)N1C(CCC1)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)CC)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(CCCNC(N)=N)NC(=O)C(NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CCSC)NC(=O)C(CCC(N)=O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(NC(=O)C(CC=1C=CC=CC=1)NC(=O)C(NC(=O)CNC(=O)C(CCC(O)=O)NC(=O)CNC(=O)C(N)CC=1NC=NC=1)C(C)O)C(C)O)C(C)C)CC1=CC=CC=C1 XVVOERDUTLJJHN-UHFFFAOYSA-N 0.000 title 1
- 229960001093 lixisenatide Drugs 0.000 title 1
- 108010004367 lixisenatide Proteins 0.000 title 1
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title 1
- 229960003105 metformin Drugs 0.000 title 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09175876.3A EP2324853B1 (en) | 2009-11-13 | 2009-11-13 | Lixisenatide as add-on to metformin in the treatment of diabetes type 2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2324853T3 true PL2324853T3 (pl) | 2016-01-29 |
Family
ID=41728467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09175876T PL2324853T3 (pl) | 2009-11-13 | 2009-11-13 | Liksysenatyd jako dodatek do metforminy w leczeniu cukrzycy typu 2 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP2324853B1 (pl) |
| CY (1) | CY1117603T1 (pl) |
| DK (1) | DK2324853T3 (pl) |
| ES (1) | ES2553593T3 (pl) |
| HR (1) | HRP20151230T1 (pl) |
| HU (1) | HUE026489T2 (pl) |
| PL (1) | PL2324853T3 (pl) |
| PT (1) | PT2324853E (pl) |
| SI (1) | SI2324853T1 (pl) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT2349324T (lt) | 2008-10-17 | 2017-12-27 | Sanofi-Aventis Deutschland Gmbh | Insulino ir glp-1 agonisto derinys |
| JP5832439B2 (ja) | 2009-11-13 | 2015-12-16 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Glp−1アゴニスト、インスリン及びメチオニンを含む薬学的組成物 |
| CN102711804B (zh) | 2009-11-13 | 2015-09-16 | 赛诺菲-安万特德国有限公司 | 包含glp-1激动剂和甲硫氨酸的药物组合物 |
| CN103179978A (zh) | 2010-08-30 | 2013-06-26 | 赛诺菲-安万特德国有限公司 | Ave0010用于制造供治疗2型糖尿病用的药物的用途 |
| CN107375909A (zh) * | 2011-02-02 | 2017-11-24 | 赛诺菲-安万特德国有限公司 | 在2型糖尿病患者中预防低血糖症 |
| US8735349B2 (en) * | 2011-05-13 | 2014-05-27 | Sanofi-Aventis Deutschland Gmbh | Method for improving glucose tolerance in a diabetes type 2 patient of younger than 50 years and having postprandial plasma glucose concentration of at least 14 mmol/L |
| ES2556466T3 (es) | 2011-05-13 | 2016-01-18 | Sanofi-Aventis Deutschland Gmbh | Lixisenatida y metformina para el tratamiento de la diabetes tipo 2 |
| US20130040878A1 (en) * | 2011-05-13 | 2013-02-14 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for use in the treatment of diabetes type 2 patients |
| US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
| WO2013030160A1 (en) | 2011-08-29 | 2013-03-07 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for use in glycemic control in diabetes type 2 patients |
| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
| MA41138B1 (fr) | 2014-12-12 | 2023-07-31 | Sanofi Aventis Deutschland | Formulation à rapport fixe d'insuline glargine/lixisenatide |
| AR103415A1 (es) * | 2015-01-16 | 2017-05-10 | Sanofi Aventis Deutschland | Tratamiento de pacientes pediátricos con diabetes mellitus de tipo 2 |
| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患治療 |
| TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第2型糖尿病病患之治療 |
| JP2023528565A (ja) | 2020-04-01 | 2023-07-05 | ハンジョウ ジョンメイ フアドン ファーマシューティカル シーオー.,エルティーディー. | Glp-1受容体アゴニストの結晶形aおよびその調製法 |
| US12421245B2 (en) | 2020-04-01 | 2025-09-23 | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | Pharmaceutically acceptable acid salt of free base of GLP1 receptor agonist, and preparation method therefor |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1076066A1 (en) | 1999-07-12 | 2001-02-14 | Zealand Pharmaceuticals A/S | Peptides for lowering blood glucose levels |
-
2009
- 2009-11-13 EP EP09175876.3A patent/EP2324853B1/en not_active Revoked
- 2009-11-13 DK DK09175876.3T patent/DK2324853T3/en active
- 2009-11-13 ES ES09175876.3T patent/ES2553593T3/es active Active
- 2009-11-13 PT PT91758763T patent/PT2324853E/pt unknown
- 2009-11-13 HU HUE09175876A patent/HUE026489T2/en unknown
- 2009-11-13 SI SI200931317T patent/SI2324853T1/sl unknown
- 2009-11-13 PL PL09175876T patent/PL2324853T3/pl unknown
-
2015
- 2015-11-16 HR HRP20151230TT patent/HRP20151230T1/hr unknown
- 2015-11-24 CY CY20151101054T patent/CY1117603T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2553593T3 (es) | 2015-12-10 |
| CY1117603T1 (el) | 2017-04-26 |
| PT2324853E (pt) | 2015-11-30 |
| SI2324853T1 (sl) | 2015-12-31 |
| EP2324853B1 (en) | 2015-08-26 |
| HUE026489T2 (en) | 2016-06-28 |
| HRP20151230T1 (hr) | 2015-12-18 |
| DK2324853T3 (en) | 2015-11-30 |
| EP2324853A1 (en) | 2011-05-25 |
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