DE602004017202D1 - Caseinhydrolysat, verfahren zur dessen herstellung sowie dessen verwendung - Google Patents

Caseinhydrolysat, verfahren zur dessen herstellung sowie dessen verwendung

Info

Publication number
DE602004017202D1
DE602004017202D1 DE602004017202T DE602004017202T DE602004017202D1 DE 602004017202 D1 DE602004017202 D1 DE 602004017202D1 DE 602004017202 T DE602004017202 T DE 602004017202T DE 602004017202 T DE602004017202 T DE 602004017202T DE 602004017202 D1 DE602004017202 D1 DE 602004017202D1
Authority
DE
Germany
Prior art keywords
pro
vivo
peptides
casein
amino acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004017202T
Other languages
English (en)
Inventor
Naoyuki Yamamoto
Seiichi Mizuno
Shingo Nishimura
Takanobu Gotou
Keiichi Matsuura
Tadashi Shinoda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Soft Drinks Co Ltd
Original Assignee
Calpis Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calpis Co Ltd filed Critical Calpis Co Ltd
Publication of DE602004017202D1 publication Critical patent/DE602004017202D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C07K5/06095—Arg-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE602004017202T 2003-08-01 2004-07-30 Caseinhydrolysat, verfahren zur dessen herstellung sowie dessen verwendung Active DE602004017202D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003285007 2003-08-01
PCT/JP2004/010928 WO2005012542A1 (ja) 2003-08-01 2004-07-30 カゼイン加水分解物、その製造法及びその用途

Publications (1)

Publication Number Publication Date
DE602004017202D1 true DE602004017202D1 (de) 2008-11-27

Family

ID=34113859

Family Applications (2)

Application Number Title Priority Date Filing Date
DE602004023210T Active DE602004023210D1 (de) 2003-08-01 2004-07-30 Biologisch nicht-abbaubares peptid, inhibitor des angiotensinumwandelnden enzyms, arzneimittel und funktionelles nahrungsmittel
DE602004017202T Active DE602004017202D1 (de) 2003-08-01 2004-07-30 Caseinhydrolysat, verfahren zur dessen herstellung sowie dessen verwendung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE602004023210T Active DE602004023210D1 (de) 2003-08-01 2004-07-30 Biologisch nicht-abbaubares peptid, inhibitor des angiotensinumwandelnden enzyms, arzneimittel und funktionelles nahrungsmittel

Country Status (23)

Country Link
US (3) US20070299014A1 (de)
EP (2) EP1669463B1 (de)
JP (3) JP4669396B2 (de)
KR (3) KR101115560B1 (de)
CN (3) CN101381401A (de)
AT (2) ATE442855T1 (de)
AU (2) AU2004261522B2 (de)
BR (2) BRPI0413238A (de)
CA (2) CA2532537A1 (de)
DE (2) DE602004023210D1 (de)
DK (2) DK1669463T3 (de)
EA (2) EA011570B1 (de)
ES (2) ES2331312T3 (de)
HK (2) HK1094008A1 (de)
MX (2) MXPA06000878A (de)
NO (2) NO20060995L (de)
NZ (2) NZ545341A (de)
PL (1) PL1669463T3 (de)
PT (2) PT1661909E (de)
TW (2) TWI349676B (de)
UA (2) UA89616C2 (de)
WO (2) WO2005012334A1 (de)
ZA (2) ZA200601739B (de)

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WO2006089921A1 (en) * 2005-02-24 2006-08-31 Dsm Ip Assets B.V. Blood pressure lowering peptides from glycomacropeptide
BRPI0611469A2 (pt) * 2005-04-28 2010-09-08 Unilever Nv usos do tripeptìdeo itp e produto alimentìcio
WO2006114193A1 (en) * 2005-04-28 2006-11-02 Unilever N.V. Peptides having an ace inhibiting effect
WO2006114194A1 (en) * 2005-04-28 2006-11-02 Unilever N.V. Peptides having a health benefit and compositions comprising them
BRPI0613979A2 (pt) 2005-07-26 2011-02-22 Calpis Co Ltd processo para a produção de leite fermentado e bebida/alimento feito a partir de leite fermentado
WO2007053390A2 (en) * 2005-10-28 2007-05-10 Nestec S.A. Methods for the use of branched chain amino acids
US20100167979A1 (en) * 2006-02-09 2010-07-01 Calpis Co. Ltd Rheumatoid arthritis-preventive agent for oral intake
JP4956164B2 (ja) * 2006-12-06 2012-06-20 味の素株式会社 メラニン輸送及び／又は放出抑制剤
MX2009010427A (es) * 2007-03-27 2009-10-20 Calpis Co Ltd Agente profilactico para la insuficiencia cardiaca.
CN101095457B (zh) * 2007-06-23 2010-04-07 临夏州华安生物制品有限责任公司 酸水解酪蛋白的生产方法
JP5750039B2 (ja) * 2008-03-26 2015-07-15 グランビア ニュートリショナルズ （アイルランド） リミテッド ロイシンリッチペプチド組成物および単離法
CN101768209B (zh) * 2009-01-05 2011-08-31 北京林业大学 具有高体内活性的降血压肽及其制备和纯化方法
CN101570568B (zh) * 2009-06-15 2012-05-30 东北农业大学 一种发酵乳中的ace抑制肽及其制备方法
CN102187935B (zh) * 2010-03-19 2012-12-19 江南大学 一种制备酪蛋白磷酸肽与ace抑制肽的方法
CN102399261B (zh) * 2010-09-07 2014-06-25 任发政 具有血管紧张素转化酶c-端选择性抑制活性的三肽及其应用和组合物
US20120115786A1 (en) * 2010-11-09 2012-05-10 Calpis Co., Ltd. Agent for reducing risk in onset of disease ascribable to non-dipper circadian rhythm of blood pressure
US9523109B2 (en) 2011-06-24 2016-12-20 Calpis Co., Ltd. Method for enzymatically preparing peptides for use in improvement of brain function
JP5718741B2 (ja) * 2011-06-24 2015-05-13 カルピス株式会社 脳機能改善用ペプチドの酵素的製造方法
WO2013056038A2 (en) * 2011-10-14 2013-04-18 Abbott Laboratories Sterilized liquid protein supplement
CN103215332A (zh) * 2013-04-16 2013-07-24 陕西科技大学 一种分步酶解羊乳酪蛋白制备ace抑制肽的方法
CN105637096A (zh) 2013-10-04 2016-06-01 英诺威有限公司 动物蛋白质的水解产物、其制造方法及其用途
FR3017536B1 (fr) * 2014-02-18 2017-05-26 Univ La Rochelle Compositions pour la prevention et/ou le traitement de pathologies liees a l'alpha-glucosidase
ES2544153B1 (es) * 2014-02-24 2016-06-06 Ntd Labs, S.L. Uso de un hidrolizado de caseína como agente antiviral
JP6251667B2 (ja) 2014-06-03 2017-12-20 アサヒカルピスウェルネス株式会社 錠剤型即放性製剤及びその製造方法
CN105693817B (zh) 2014-11-27 2020-06-05 西北大学 一类三肽化合物及其制备方法与应用
JP6005202B2 (ja) * 2015-03-19 2016-10-12 アサヒグループホールディングス株式会社 脳機能改善用ペプチドの酵素的製造方法
JP6625366B2 (ja) * 2015-08-05 2019-12-25 学校法人北里研究所 豚肉の熟成中に生成する生理活性ペプチドを含む血圧降下剤及び食品、並びにペプチドを指標とする豚肉の熟成評価法
CN106119325A (zh) * 2016-06-23 2016-11-16 哈尔滨商业大学 一种具有增加肌肉含量和力量作用的酪蛋白水解物的制备方法
CN107375897A (zh) * 2017-08-15 2017-11-24 普维食品发展（上海）有限公司 一种辅助降血压的组合物及其用途
CN107348511B (zh) * 2017-08-21 2018-04-06 东方红（通化）生物医药股份有限公司 一种具有辅助降血压作用的西洋参/人参提取物的发酵提取方法
CN108003231A (zh) * 2017-11-13 2018-05-08 江苏大学 一种降低小分子肽中游离氨基酸含量的方法
CN108588156A (zh) * 2018-04-24 2018-09-28 浙江大学 一种水牛乳酪蛋白抗氧化活性肽的制备方法
KR20210003108A (ko) * 2018-04-26 2021-01-11 제리아 신야쿠 고교 가부시키 가이샤 디펩티드 및 이것을 함유하는 의약 조성물
CN110467649A (zh) * 2019-09-12 2019-11-19 浙江省农业科学院 一种抑制血管紧张素转换酶活性的多肽qeip及其应用
CN113321719B (zh) * 2021-05-20 2022-03-18 澳优乳业（中国）有限公司 一种寡肽及其制备方法与应用
CN114656521B (zh) * 2022-04-01 2023-08-18 广西大学 抑制新型冠状病毒刺突蛋白与ace2结合的化合物及其应用

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Also Published As

Publication number Publication date
PT1669463E (pt) 2009-01-23
AU2004261855B2 (en) 2010-09-16
EP1661909B1 (de) 2009-09-16
UA89616C2 (ru) 2010-02-25
MXPA06000878A (es) 2006-03-30
KR20110039379A (ko) 2011-04-15
WO2005012334A1 (ja) 2005-02-10
DK1661909T3 (da) 2010-01-18
CN100398661C (zh) 2008-07-02
ZA200601739B (en) 2007-05-30
TWI349676B (en) 2011-10-01
DE602004023210D1 (de) 2009-10-29
EP1669463B1 (de) 2008-10-15
EP1669463A4 (de) 2006-08-23
EA200600349A1 (ru) 2006-08-25
BRPI0413238A (pt) 2006-10-03
ES2331312T3 (es) 2009-12-29
CN100439393C (zh) 2008-12-03
KR20060120567A (ko) 2006-11-27
CN1832958A (zh) 2006-09-13
ES2313067T3 (es) 2009-03-01
CN1833031A (zh) 2006-09-13
EP1661909A4 (de) 2006-08-30
ATE442855T1 (de) 2009-10-15
NO20060995L (no) 2006-02-28
NO20060994L (no) 2006-02-28
JP5341300B2 (ja) 2013-11-13
NZ545341A (en) 2009-06-26
CA2532537A1 (en) 2005-02-10
UA87278C2 (ru) 2009-07-10
US20110082281A1 (en) 2011-04-07
AU2004261855A1 (en) 2005-02-10
JPWO2005012542A1 (ja) 2007-09-27
CN101381401A (zh) 2009-03-11
MXPA06000879A (es) 2006-03-30
JPWO2005012334A1 (ja) 2008-01-17
PL1669463T3 (pl) 2009-02-27
KR101174299B1 (ko) 2012-08-16
JP2011102327A (ja) 2011-05-26
US8580557B2 (en) 2013-11-12
TW200507869A (en) 2005-03-01
TWI341866B (en) 2011-05-11
EA011570B1 (ru) 2009-04-28
BRPI0413242A (pt) 2006-10-03
WO2005012542A1 (ja) 2005-02-10
AU2004261522A1 (en) 2005-02-10
EA200600352A1 (ru) 2006-08-25
PT1661909E (pt) 2009-12-17
TW200505471A (en) 2005-02-16
KR101115560B1 (ko) 2012-03-13
HK1094008A1 (en) 2007-03-16
CA2546497A1 (en) 2005-02-10
US20070299014A1 (en) 2007-12-27
EP1669463A1 (de) 2006-06-14
KR101115557B1 (ko) 2012-03-13
HK1093991A1 (en) 2007-03-16
US20070122451A1 (en) 2007-05-31
KR20060118395A (ko) 2006-11-23
ZA200601746B (en) 2007-05-30
DK1669463T3 (da) 2009-01-26
EA010098B1 (ru) 2008-06-30
JP4669396B2 (ja) 2011-04-13
WO2005012334A8 (ja) 2005-06-30
AU2004261522B2 (en) 2010-09-16
NZ545340A (en) 2010-04-30
ATE411035T1 (de) 2008-10-15
EP1661909A1 (de) 2006-05-31

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