DK1661909T3 - Biologisk ikke-nedbrydeligt peptid, angiotensinomdannende enzyminhibitor, medikament og funktionel fødevare - Google Patents

Biologisk ikke-nedbrydeligt peptid, angiotensinomdannende enzyminhibitor, medikament og funktionel fødevare

Info

Publication number
DK1661909T3
DK1661909T3 DK04771089.2T DK04771089T DK1661909T3 DK 1661909 T3 DK1661909 T3 DK 1661909T3 DK 04771089 T DK04771089 T DK 04771089T DK 1661909 T3 DK1661909 T3 DK 1661909T3
Authority
DK
Denmark
Prior art keywords
pro
drug
converting enzyme
functional food
enzyme inhibitor
Prior art date
Application number
DK04771089.2T
Other languages
English (en)
Inventor
N Yamamoto
S Nishimura
S Mizuno
T Gotou
K Matsuura
Original Assignee
Calpis Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calpis Co Ltd filed Critical Calpis Co Ltd
Application granted granted Critical
Publication of DK1661909T3 publication Critical patent/DK1661909T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C07K5/06095—Arg-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK04771089.2T 2003-08-01 2004-07-30 Biologisk ikke-nedbrydeligt peptid, angiotensinomdannende enzyminhibitor, medikament og funktionel fødevare DK1661909T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003285007 2003-08-01
PCT/JP2004/010929 WO2005012334A1 (ja) 2003-08-01 2004-07-30 生体内非分解性ペプチド、アンジオテンシン変換酵素阻害剤、医薬及び機能性食品

Publications (1)

Publication Number Publication Date
DK1661909T3 true DK1661909T3 (da) 2010-01-18

Family

ID=34113859

Family Applications (2)

Application Number Title Priority Date Filing Date
DK04771089.2T DK1661909T3 (da) 2003-08-01 2004-07-30 Biologisk ikke-nedbrydeligt peptid, angiotensinomdannende enzyminhibitor, medikament og funktionel fødevare
DK04771088T DK1669463T3 (da) 2003-08-01 2004-07-30 Kaseinhydrolysat, fremgangsmåde til fremstilling af dette og anvendelse af dette

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK04771088T DK1669463T3 (da) 2003-08-01 2004-07-30 Kaseinhydrolysat, fremgangsmåde til fremstilling af dette og anvendelse af dette

Country Status (23)

Country Link
US (3) US20070299014A1 (da)
EP (2) EP1669463B1 (da)
JP (3) JP4669396B2 (da)
KR (3) KR101115560B1 (da)
CN (3) CN100398661C (da)
AT (2) ATE442855T1 (da)
AU (2) AU2004261855B2 (da)
BR (2) BRPI0413242A (da)
CA (2) CA2532537A1 (da)
DE (2) DE602004017202D1 (da)
DK (2) DK1661909T3 (da)
EA (2) EA010098B1 (da)
ES (2) ES2331312T3 (da)
HK (2) HK1094008A1 (da)
MX (2) MXPA06000879A (da)
NO (2) NO20060995L (da)
NZ (2) NZ545340A (da)
PL (1) PL1669463T3 (da)
PT (2) PT1661909E (da)
TW (2) TWI341866B (da)
UA (2) UA89616C2 (da)
WO (2) WO2005012542A1 (da)
ZA (2) ZA200601739B (da)

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BRPI0611469A2 (pt) * 2005-04-28 2010-09-08 Unilever Nv usos do tripeptìdeo itp e produto alimentìcio
KR20080040683A (ko) 2005-07-26 2008-05-08 칼피스가부시키가이샤 발효유의 제조 방법 및 발효유 음식품
RU2008121259A (ru) * 2005-10-28 2009-12-10 Нестек С.А. (Ch) Пищевой продукт, содержащий аминокислоту с разветвленной цепью, и способ лечения с его использованием
JP5096173B2 (ja) * 2006-02-09 2012-12-12 カルピス株式会社 経口摂取用関節リウマチ抑制剤
JP4956164B2 (ja) * 2006-12-06 2012-06-20 味の素株式会社 メラニン輸送及び／又は放出抑制剤
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CN102014947B (zh) * 2008-03-26 2016-10-19 格兰比亚营养物(爱尔兰)有限公司 富含亮氨酸的肽组合物和分离方法
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CN101570568B (zh) * 2009-06-15 2012-05-30 东北农业大学 一种发酵乳中的ace抑制肽及其制备方法
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CN105637096A (zh) * 2013-10-04 2016-06-01 英诺威有限公司 动物蛋白质的水解产物、其制造方法及其用途
FR3017536B1 (fr) * 2014-02-18 2017-05-26 Univ La Rochelle Compositions pour la prevention et/ou le traitement de pathologies liees a l'alpha-glucosidase
ES2544153B1 (es) * 2014-02-24 2016-06-06 Ntd Labs, S.L. Uso de un hidrolizado de caseína como agente antiviral
JP6251667B2 (ja) 2014-06-03 2017-12-20 アサヒカルピスウェルネス株式会社 錠剤型即放性製剤及びその製造方法
CN105693817B (zh) 2014-11-27 2020-06-05 西北大学 一类三肽化合物及其制备方法与应用
JP6005202B2 (ja) * 2015-03-19 2016-10-12 アサヒグループホールディングス株式会社 脳機能改善用ペプチドの酵素的製造方法
JP6625366B2 (ja) * 2015-08-05 2019-12-25 学校法人北里研究所 豚肉の熟成中に生成する生理活性ペプチドを含む血圧降下剤及び食品、並びにペプチドを指標とする豚肉の熟成評価法
CN106119325A (zh) * 2016-06-23 2016-11-16 哈尔滨商业大学 一种具有增加肌肉含量和力量作用的酪蛋白水解物的制备方法
CN107375897A (zh) * 2017-08-15 2017-11-24 普维食品发展（上海）有限公司 一种辅助降血压的组合物及其用途
CN107348511B (zh) * 2017-08-21 2018-04-06 东方红（通化）生物医药股份有限公司 一种具有辅助降血压作用的西洋参/人参提取物的发酵提取方法
CN108003231A (zh) * 2017-11-13 2018-05-08 江苏大学 一种降低小分子肽中游离氨基酸含量的方法
CN108588156A (zh) * 2018-04-24 2018-09-28 浙江大学 一种水牛乳酪蛋白抗氧化活性肽的制备方法
JPWO2019208700A1 (ja) * 2018-04-26 2021-04-30 ゼリア新薬工業株式会社 ジペプチド及びこれを含有する医薬組成物
CN110467649A (zh) * 2019-09-12 2019-11-19 浙江省农业科学院 一种抑制血管紧张素转换酶活性的多肽qeip及其应用
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Also Published As

Publication number Publication date
CA2532537A1 (en) 2005-02-10
TWI349676B (en) 2011-10-01
JPWO2005012334A1 (ja) 2008-01-17
US8580557B2 (en) 2013-11-12
KR20110039379A (ko) 2011-04-15
KR101115560B1 (ko) 2012-03-13
US20110082281A1 (en) 2011-04-07
WO2005012334A1 (ja) 2005-02-10
TW200505471A (en) 2005-02-16
EP1669463B1 (en) 2008-10-15
EA010098B1 (ru) 2008-06-30
TW200507869A (en) 2005-03-01
KR20060118395A (ko) 2006-11-23
CN100398661C (zh) 2008-07-02
CN100439393C (zh) 2008-12-03
CN101381401A (zh) 2009-03-11
AU2004261522A1 (en) 2005-02-10
JPWO2005012542A1 (ja) 2007-09-27
BRPI0413242A (pt) 2006-10-03
US20070122451A1 (en) 2007-05-31
DE602004017202D1 (de) 2008-11-27
DE602004023210D1 (de) 2009-10-29
NZ545341A (en) 2009-06-26
ZA200601746B (en) 2007-05-30
US20070299014A1 (en) 2007-12-27
WO2005012542A1 (ja) 2005-02-10
AU2004261855A1 (en) 2005-02-10
WO2005012334A8 (ja) 2005-06-30
BRPI0413238A (pt) 2006-10-03
NZ545340A (en) 2010-04-30
UA89616C2 (ru) 2010-02-25
CA2546497A1 (en) 2005-02-10
EP1661909B1 (en) 2009-09-16
EA200600349A1 (ru) 2006-08-25
NO20060995L (no) 2006-02-28
KR101174299B1 (ko) 2012-08-16
DK1669463T3 (da) 2009-01-26
EP1669463A4 (en) 2006-08-23
EA011570B1 (ru) 2009-04-28
JP5341300B2 (ja) 2013-11-13
KR101115557B1 (ko) 2012-03-13
CN1833031A (zh) 2006-09-13
MXPA06000879A (es) 2006-03-30
EP1661909A1 (en) 2006-05-31
EP1669463A1 (en) 2006-06-14
EP1661909A4 (en) 2006-08-30
ES2331312T3 (es) 2009-12-29
HK1093991A1 (en) 2007-03-16
JP4669396B2 (ja) 2011-04-13
KR20060120567A (ko) 2006-11-27
CN1832958A (zh) 2006-09-13
NO20060994L (no) 2006-02-28
ZA200601739B (en) 2007-05-30
ES2313067T3 (es) 2009-03-01
PL1669463T3 (pl) 2009-02-27
PT1661909E (pt) 2009-12-17
AU2004261855B2 (en) 2010-09-16
UA87278C2 (ru) 2009-07-10
MXPA06000878A (es) 2006-03-30
PT1669463E (pt) 2009-01-23
TWI341866B (en) 2011-05-11
HK1094008A1 (en) 2007-03-16
JP2011102327A (ja) 2011-05-26
EA200600352A1 (ru) 2006-08-25
AU2004261522B2 (en) 2010-09-16
ATE411035T1 (de) 2008-10-15
ATE442855T1 (de) 2009-10-15

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