HK1094008A1 - Casein hydrolyzate, process for producing the same and use thereof - Google Patents

Casein hydrolyzate, process for producing the same and use thereof

Info

Publication number
HK1094008A1
HK1094008A1 HK07100122.4A HK07100122A HK1094008A1 HK 1094008 A1 HK1094008 A1 HK 1094008A1 HK 07100122 A HK07100122 A HK 07100122A HK 1094008 A1 HK1094008 A1 HK 1094008A1
Authority
HK
Hong Kong
Prior art keywords
pro
vivo
peptides
casein
amino acids
Prior art date
Application number
HK07100122.4A
Other languages
English (en)
Inventor
Naoyuki Yamamoto
Seiichi Mizuno
Shingo Nishimura
Takanobu Gotou
Keiichi Matsuura
Tadashi Shinoda
Original Assignee
Calpis Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calpis Co Ltd filed Critical Calpis Co Ltd
Publication of HK1094008A1 publication Critical patent/HK1094008A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/18Peptides; Protein hydrolysates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06086Dipeptides with the first amino acid being basic
    • C07K5/06095Arg-amino acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK07100122.4A 2003-08-01 2007-01-04 Casein hydrolyzate, process for producing the same and use thereof HK1094008A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003285007 2003-08-01
PCT/JP2004/010928 WO2005012542A1 (ja) 2003-08-01 2004-07-30 カゼイン加水分解物、その製造法及びその用途

Publications (1)

Publication Number Publication Date
HK1094008A1 true HK1094008A1 (en) 2007-03-16

Family

ID=34113859

Family Applications (2)

Application Number Title Priority Date Filing Date
HK07100123.3A HK1093991A1 (en) 2003-08-01 2007-01-04 Biologically non-degradable peptide, angiotensin converting enzyme inhibitor, drug and functional food
HK07100122.4A HK1094008A1 (en) 2003-08-01 2007-01-04 Casein hydrolyzate, process for producing the same and use thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK07100123.3A HK1093991A1 (en) 2003-08-01 2007-01-04 Biologically non-degradable peptide, angiotensin converting enzyme inhibitor, drug and functional food

Country Status (23)

Country Link
US (3) US20070299014A1 (de)
EP (2) EP1661909B1 (de)
JP (3) JP4669396B2 (de)
KR (3) KR101115557B1 (de)
CN (3) CN101381401A (de)
AT (2) ATE442855T1 (de)
AU (2) AU2004261522B2 (de)
BR (2) BRPI0413238A (de)
CA (2) CA2546497A1 (de)
DE (2) DE602004023210D1 (de)
DK (2) DK1669463T3 (de)
EA (2) EA010098B1 (de)
ES (2) ES2313067T3 (de)
HK (2) HK1093991A1 (de)
MX (2) MXPA06000879A (de)
NO (2) NO20060995L (de)
NZ (2) NZ545341A (de)
PL (1) PL1669463T3 (de)
PT (2) PT1669463E (de)
TW (2) TWI349676B (de)
UA (2) UA87278C2 (de)
WO (2) WO2005012542A1 (de)
ZA (2) ZA200601739B (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA016396B1 (ru) * 2005-02-24 2012-04-30 ДСМ АйПи АССЕТС Б.В. Способ получения пептидного гидролизата, содержащего ipp, и применение указанного гидролизата для производства функционального пищевого продукта, предназначенного для поддержания здоровья сердечно-сосудистой системы
US20090304869A1 (en) * 2005-04-28 2009-12-10 Christianus Jacobus Van Platerink Peptides Having an Ace Inhibiting Effect
BRPI0612923A2 (pt) * 2005-04-28 2010-12-07 Unilever Nv uso do tripeptìdeo map, uso do tripeptìdeo map em combinação com o tripeptìdeo itp e produto alimentìcio
US20090325888A1 (en) * 2005-04-28 2009-12-31 Luppo Edens Peptides having a health benefit and compositions comprising them
KR20080040683A (ko) 2005-07-26 2008-05-08 칼피스가부시키가이샤 발효유의 제조 방법 및 발효유 음식품
AU2006309040B2 (en) 2005-10-28 2011-10-06 Nestec S.A. Methods for the use of branched chain amino acids
JP5096173B2 (ja) * 2006-02-09 2012-12-12 カルピス株式会社 経口摂取用関節リウマチ抑制剤
JP4956164B2 (ja) * 2006-12-06 2012-06-20 味の素株式会社 メラニン輸送及び/又は放出抑制剤
BRPI0809319A2 (pt) * 2007-03-27 2014-09-23 Calpis Co Ltd Agente para suprimir espessamento de parede de coração, agente profilático para hipertrofia cardíaca, agente profilático para insuficiência cardíaca, e, alimento funcional
CN101095457B (zh) * 2007-06-23 2010-04-07 临夏州华安生物制品有限责任公司 酸水解酪蛋白的生产方法
CA2719857C (en) * 2008-03-26 2019-08-06 Glanbia Nutritionals (Ireland) Ltd. Leucine-rich peptide compositions and methods for isolation
CN101768209B (zh) * 2009-01-05 2011-08-31 北京林业大学 具有高体内活性的降血压肽及其制备和纯化方法
CN101570568B (zh) * 2009-06-15 2012-05-30 东北农业大学 一种发酵乳中的ace抑制肽及其制备方法
CN102187935B (zh) * 2010-03-19 2012-12-19 江南大学 一种制备酪蛋白磷酸肽与ace抑制肽的方法
CN102399261B (zh) * 2010-09-07 2014-06-25 任发政 具有血管紧张素转化酶c-端选择性抑制活性的三肽及其应用和组合物
US20120115786A1 (en) * 2010-11-09 2012-05-10 Calpis Co., Ltd. Agent for reducing risk in onset of disease ascribable to non-dipper circadian rhythm of blood pressure
US9523109B2 (en) 2011-06-24 2016-12-20 Calpis Co., Ltd. Method for enzymatically preparing peptides for use in improvement of brain function
JP5718741B2 (ja) * 2011-06-24 2015-05-13 カルピス株式会社 脳機能改善用ペプチドの酵素的製造方法
BR112014009000A2 (pt) * 2011-10-14 2017-05-02 Abbott Lab suplemento proteico líquido esterilizado
CN103215332A (zh) * 2013-04-16 2013-07-24 陕西科技大学 一种分步酶解羊乳酪蛋白制备ace抑制肽的方法
JP6306197B2 (ja) 2013-10-04 2018-04-04 イノウェイ・カンパニー・リミテッド 動物性タンパク加水分解物、その製造方法及びその用途
FR3017536B1 (fr) * 2014-02-18 2017-05-26 Univ La Rochelle Compositions pour la prevention et/ou le traitement de pathologies liees a l'alpha-glucosidase
ES2544153B1 (es) * 2014-02-24 2016-06-06 Ntd Labs, S.L. Uso de un hidrolizado de caseína como agente antiviral
JP6251667B2 (ja) 2014-06-03 2017-12-20 アサヒカルピスウェルネス株式会社 錠剤型即放性製剤及びその製造方法
CN105693817B (zh) 2014-11-27 2020-06-05 西北大学 一类三肽化合物及其制备方法与应用
JP6005202B2 (ja) * 2015-03-19 2016-10-12 アサヒグループホールディングス株式会社 脳機能改善用ペプチドの酵素的製造方法
JP6625366B2 (ja) * 2015-08-05 2019-12-25 学校法人北里研究所 豚肉の熟成中に生成する生理活性ペプチドを含む血圧降下剤及び食品、並びにペプチドを指標とする豚肉の熟成評価法
CN106119325A (zh) * 2016-06-23 2016-11-16 哈尔滨商业大学 一种具有增加肌肉含量和力量作用的酪蛋白水解物的制备方法
CN107375897A (zh) * 2017-08-15 2017-11-24 普维食品发展(上海)有限公司 一种辅助降血压的组合物及其用途
CN107348511B (zh) * 2017-08-21 2018-04-06 东方红(通化)生物医药股份有限公司 一种具有辅助降血压作用的西洋参/人参提取物的发酵提取方法
CN108003231A (zh) * 2017-11-13 2018-05-08 江苏大学 一种降低小分子肽中游离氨基酸含量的方法
CN108588156A (zh) * 2018-04-24 2018-09-28 浙江大学 一种水牛乳酪蛋白抗氧化活性肽的制备方法
CN112041328A (zh) * 2018-04-26 2020-12-04 志瑞亚新药工业株式会社 二肽和含有该二肽的药物组合物
CN110467649A (zh) * 2019-09-12 2019-11-19 浙江省农业科学院 一种抑制血管紧张素转换酶活性的多肽qeip及其应用
CN113321719B (zh) * 2021-05-20 2022-03-18 澳优乳业(中国)有限公司 一种寡肽及其制备方法与应用
CN114656521B (zh) * 2022-04-01 2023-08-18 广西大学 抑制新型冠状病毒刺突蛋白与ace2结合的化合物及其应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6023087B2 (ja) * 1982-09-04 1985-06-05 工業技術院長 アンジオテンシン転換酵素阻害剤
FR2608051B1 (fr) * 1986-12-15 1989-04-07 Bellon Labor Sa Roger Procede de fabrication d'un hydrolysat enzymatique de proteines riche en di- et tri-peptides, utilisable notamment en nutrition artificielle et en dietetique
JPH0630615B2 (ja) * 1988-07-27 1994-04-27 江崎グリコ株式会社 低分子ペプチド組成物及びその製造方法
JPH0262828A (ja) 1988-08-26 1990-03-02 Ajinomoto Co Inc 新規ベプチドおよびこれを含有する降圧剤
JPH03120225A (ja) 1989-10-04 1991-05-22 Ajinomoto Co Inc 新規ペプチドおよびこれを含有する降圧剤
EP0457565B1 (de) * 1990-05-18 1997-07-30 Morinaga Milk Industry Co., Ltd. Milchproteinhydrolysate und Zusammensetzungen zur Verwendung als Haar- und Hautbehandlungsmittel
JP3010795B2 (ja) * 1991-07-04 2000-02-21 不二製油株式会社 ペプチドの苦味除去方法
JP3378279B2 (ja) 1991-11-07 2003-02-17 株式会社日清製粉グループ本社 ペプチドおよびその製造方法
JPH05252979A (ja) * 1992-02-28 1993-10-05 Nippon Steel Corp 低分子ペプチドの製造方法
JP2782142B2 (ja) 1992-07-23 1998-07-30 カルピス株式会社 アンジオテンシン変換酵素阻害剤及びその製造法
DK46793D0 (da) * 1993-04-26 1993-04-26 Novo Nordisk As Enzym
AU7381098A (en) * 1997-05-16 1998-12-08 Novo Nordisk Biotech, Inc. Polypeptides having prolyl pipeptidyl aminopeptidase activity and nucleic acids encoding same
JP2873327B2 (ja) * 1998-01-23 1999-03-24 工業技術院長 アンジオテンシン変換酵素阻害剤
JP4633876B2 (ja) * 1999-11-11 2011-02-16 カルピス株式会社 トリペプチドの製造方法
CN1140190C (zh) * 1999-11-29 2004-03-03 协和发酵工业株式会社 食盐味增强方法、食盐味增强剂、食盐味调料以及食盐味增强食品
JP4490547B2 (ja) * 2000-03-30 2010-06-30 株式会社 レオロジー機能食品研究所 新規ペプチド、その製造法及び用途
JP4436961B2 (ja) * 2000-07-25 2010-03-24 森永乳業株式会社 蛋白質加水分解物の製造方法
JP2003024012A (ja) * 2001-07-18 2003-01-28 National Institute Of Advanced Industrial & Technology アンジオテンシンi変換酵素阻害剤及び血圧降下性機能食品
DK1457498T3 (da) * 2001-11-21 2007-06-04 Morinaga Milk Industry Co Ltd Hidtil ukendt peptid med angiotensinkonvertaseinhibitorisk virkning
JP2003210138A (ja) 2002-01-24 2003-07-29 Yoko Takenaka 機能性食品、その製造方法及び医薬
US7900438B2 (en) * 2006-07-28 2011-03-08 General Electric Company Heat transfer system and method for turbine engine using heat pipes

Also Published As

Publication number Publication date
AU2004261522B2 (en) 2010-09-16
EA011570B1 (ru) 2009-04-28
DK1661909T3 (da) 2010-01-18
DE602004023210D1 (de) 2009-10-29
NO20060994L (no) 2006-02-28
CN100398661C (zh) 2008-07-02
EP1669463A1 (de) 2006-06-14
ES2313067T3 (es) 2009-03-01
UA87278C2 (ru) 2009-07-10
PL1669463T3 (pl) 2009-02-27
US20070122451A1 (en) 2007-05-31
TWI349676B (en) 2011-10-01
AU2004261855A1 (en) 2005-02-10
WO2005012334A1 (ja) 2005-02-10
CA2546497A1 (en) 2005-02-10
KR101115560B1 (ko) 2012-03-13
ZA200601746B (en) 2007-05-30
JP2011102327A (ja) 2011-05-26
MXPA06000879A (es) 2006-03-30
ATE442855T1 (de) 2009-10-15
PT1661909E (pt) 2009-12-17
DE602004017202D1 (de) 2008-11-27
TW200505471A (en) 2005-02-16
CN1832958A (zh) 2006-09-13
UA89616C2 (ru) 2010-02-25
BRPI0413242A (pt) 2006-10-03
CN1833031A (zh) 2006-09-13
KR20060118395A (ko) 2006-11-23
EP1669463A4 (de) 2006-08-23
JP4669396B2 (ja) 2011-04-13
KR20060120567A (ko) 2006-11-27
NZ545340A (en) 2010-04-30
CA2532537A1 (en) 2005-02-10
KR20110039379A (ko) 2011-04-15
BRPI0413238A (pt) 2006-10-03
EA200600352A1 (ru) 2006-08-25
WO2005012334A8 (ja) 2005-06-30
TW200507869A (en) 2005-03-01
EP1661909A4 (de) 2006-08-30
PT1669463E (pt) 2009-01-23
US20070299014A1 (en) 2007-12-27
AU2004261855B2 (en) 2010-09-16
JPWO2005012334A1 (ja) 2008-01-17
EP1661909A1 (de) 2006-05-31
MXPA06000878A (es) 2006-03-30
CN101381401A (zh) 2009-03-11
CN100439393C (zh) 2008-12-03
ES2331312T3 (es) 2009-12-29
TWI341866B (en) 2011-05-11
EP1661909B1 (de) 2009-09-16
HK1093991A1 (en) 2007-03-16
WO2005012542A1 (ja) 2005-02-10
JPWO2005012542A1 (ja) 2007-09-27
ATE411035T1 (de) 2008-10-15
ZA200601739B (en) 2007-05-30
JP5341300B2 (ja) 2013-11-13
AU2004261522A1 (en) 2005-02-10
NZ545341A (en) 2009-06-26
EP1669463B1 (de) 2008-10-15
US8580557B2 (en) 2013-11-12
KR101174299B1 (ko) 2012-08-16
KR101115557B1 (ko) 2012-03-13
DK1669463T3 (da) 2009-01-26
EA200600349A1 (ru) 2006-08-25
NO20060995L (no) 2006-02-28
EA010098B1 (ru) 2008-06-30
US20110082281A1 (en) 2011-04-07

Similar Documents

Publication Publication Date Title
HK1094008A1 (en) Casein hydrolyzate, process for producing the same and use thereof
WO2003037932A3 (en) Human coagulation factor vii polypeptides
MXPA01007956A (es) Polipeptido antimicrobiano/neutralizador de endotoxina.
ATE272328T1 (de) Verwendungen einer zusammensetzung enthaltend teilweise hydrolysiertes fischgelatin
JP6864539B2 (ja) コラーゲン、ゼラチンおよびコラーゲン加水分解物に含まれるGly−X−Y配列量の測定方法、およびX−Y配列量の測定方法
Gilmartin et al. Production of cod (Gadus morhua) muscle hydrolysates. Influence of combinations of commercial enzyme preparations on hydrolysate peptide size range
DE602005024809D1 (de) Verfahren zur herstellung von gabapentin
HK1090085A1 (en) Novel photobacterium damselae nucleotide and amino acid sequences and uses thereof
MY141221A (en) Casein hydrolyzate, process for producing the same, and use thereof
EE200000478A (et) Peptiid, seda kodeeriv geen, diagnostiline reagent ja diagnostiline reaktiivikomplekt ning vaktsiinkasutamiseks riketsioosi ravis
WO2005116658A3 (en) Method for determining a tissue degradation process by detection of comp neoepitopes
ATE281522T1 (de) Sentrin-spezifische menschliche protease senp1
MXPA05009954A (es) Familia de proteinas secretadas.
WO2004046199A3 (fr) Procede d'obtention d'acide chondroitine sulfurique et ses utilisations
WO2003060516A1 (fr) Methode de criblage
WO2003083472A1 (fr) Methode d'evaluation du risque de maladie parodontale
MX2021014268A (es) Proteina optimizada que comprende los aminoacidos esenciales para la nutricion humana.
WO2000027374A3 (en) The use of excitatory amino acid transporter inhibitors to reduce cns white matter injury
WO1998050423A3 (fr) Analogues peptidiques et leurs utilisations notamment dans des compositions pharmaceutiques et pour le diagnostic
WO2004056863A8 (en) Splice variant of human placental growth hormone
WO2003089461A3 (en) Purified dutpase from helicobacter pylori
TH62270A (th) ไฮโดรไลเสทของโปรตีนหางนมที่แสดงฤทธิ์ทางชีวภาพได้ที่ได้รับการปรับปรุง
WO2002050116A3 (en) Adhesion molecule protein

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130730