DE2720245C2 - Peptide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Zusammensetzungen - Google Patents

Peptide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Zusammensetzungen

Info

Publication number
DE2720245C2
DE2720245C2 DE2720245A DE2720245A DE2720245C2 DE 2720245 C2 DE2720245 C2 DE 2720245C2 DE 2720245 A DE2720245 A DE 2720245A DE 2720245 A DE2720245 A DE 2720245A DE 2720245 C2 DE2720245 C2 DE 2720245C2
Authority
DE
Germany
Prior art keywords
mmol
methanol
solution
tyr
dimethylformamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2720245A
Other languages
German (de)
English (en)
Other versions
DE2720245A1 (de
Inventor
Anand Swaroop Dutta
Barrington John Albert Furr
Michael Brian Macclesfield Cheshire Giles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of DE2720245A1 publication Critical patent/DE2720245A1/de
Application granted granted Critical
Publication of DE2720245C2 publication Critical patent/DE2720245C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C07K5/06095—Arg-amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Fodder In General (AREA)
  • Medicines Containing Plant Substances (AREA)
DE2720245A 1976-05-11 1977-05-05 Peptide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Zusammensetzungen Expired DE2720245C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB19327/76A GB1524747A (en) 1976-05-11 1976-05-11 Polypeptide

Publications (2)

Publication Number Publication Date
DE2720245A1 DE2720245A1 (de) 1977-11-24
DE2720245C2 true DE2720245C2 (de) 1986-09-25

Family

ID=10127509

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2720245A Expired DE2720245C2 (de) 1976-05-11 1977-05-05 Peptide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Zusammensetzungen

Country Status (27)

Country Link
US (1) US4100274A (OSRAM)
JP (1) JPS52136172A (OSRAM)
AT (2) AT379400B (OSRAM)
AU (1) AU508025B2 (OSRAM)
BE (1) BE854467A (OSRAM)
BG (1) BG60740B2 (OSRAM)
CA (1) CA1101844A (OSRAM)
CH (2) CH627151A5 (OSRAM)
CS (1) CS199673B2 (OSRAM)
DD (1) DD136738A5 (OSRAM)
DE (1) DE2720245C2 (OSRAM)
DK (1) DK149596C (OSRAM)
ES (1) ES458691A1 (OSRAM)
FI (1) FI64139C (OSRAM)
FR (1) FR2351092A1 (OSRAM)
GB (1) GB1524747A (OSRAM)
HU (1) HU179990B (OSRAM)
IE (1) IE44426B1 (OSRAM)
IL (1) IL52014A (OSRAM)
NL (2) NL191793C (OSRAM)
NO (2) NO147304C (OSRAM)
NZ (1) NZ183931A (OSRAM)
PL (2) PL108860B1 (OSRAM)
SE (2) SE437837B (OSRAM)
SU (1) SU910116A3 (OSRAM)
YU (1) YU40672B (OSRAM)
ZA (1) ZA772433B (OSRAM)

Cited By (5)

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US8133507B2 (en) 2002-12-13 2012-03-13 Durect Corporation Oral drug delivery system
US8153149B2 (en) 2004-09-17 2012-04-10 Durect Corporation Controlled delivery system
US8415401B2 (en) 2007-12-06 2013-04-09 Durect Corporation Oral pharmaceutical dosage forms
US8956644B2 (en) 2006-11-03 2015-02-17 Durect Corporation Transdermal delivery systems
US9555113B2 (en) 2013-03-15 2017-01-31 Durect Corporation Compositions with a rheological modifier to reduce dissolution variability

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US4760053A (en) * 1984-08-02 1988-07-26 Fernand Labrie Combination therapy for selected sex steroid dependent cancers
US4666885A (en) * 1985-02-08 1987-05-19 Fernand Labrie Combination therapy for treatment of female breast cancer
US4705778A (en) * 1985-10-22 1987-11-10 Sri International Orally active LHRH analogs
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NL191793C (nl) 1996-08-02
JPS52136172A (en) 1977-11-14
PL104362B1 (pl) 1979-08-31
NO149586C (no) 1984-05-16
ATA335877A (de) 1985-05-15
NL7705130A (nl) 1977-11-15
DD136738A5 (de) 1979-07-25
PL108860B1 (en) 1980-05-31
IL52014A0 (en) 1977-07-31
NZ183931A (en) 1979-03-16
GB1524747A (en) 1978-09-13
AT365562B (de) 1982-01-25
YU117277A (en) 1983-02-28
ATA217979A (de) 1981-06-15
NL191793B (nl) 1996-04-01
AT379400B (de) 1985-12-27
NO822984L (no) 1977-11-14
YU40672B (en) 1986-04-30
PL197889A1 (pl) 1978-02-13
CH627151A5 (OSRAM) 1981-12-31
DK207977A (da) 1977-11-12
IE44426L (en) 1977-11-11
CA1101844A (en) 1981-05-26
SE437993B (sv) 1985-03-25
AU2468177A (en) 1978-11-02
DK149596B (da) 1986-08-04
FI64139C (fi) 1983-10-10
BE854467A (fr) 1977-11-10
DK149596C (da) 1987-01-05
NO149586B (no) 1984-02-06
SU910116A3 (ru) 1982-02-28
DE2720245A1 (de) 1977-11-24
FI771480A7 (OSRAM) 1977-11-12
CH629475A5 (de) 1982-04-30
FI64139B (fi) 1983-06-30
IE44426B1 (en) 1981-11-18
JPS6113480B2 (OSRAM) 1986-04-14
ES458691A1 (es) 1978-08-16
SE7705432L (sv) 1977-11-12
FR2351092B1 (OSRAM) 1980-02-22
US4100274A (en) 1978-07-11
NO771644L (no) 1977-11-14
ZA772433B (en) 1978-03-29
SE437837B (sv) 1985-03-18
FR2351092A1 (fr) 1977-12-09
IL52014A (en) 1979-11-30
NL970002I2 (nl) 1997-05-01
CS199673B2 (en) 1980-07-31
NL970002I1 (nl) 1997-03-03
HU179990B (en) 1983-01-28
AU508025B2 (en) 1980-03-06
SE8007763L (sv) 1980-11-05
NO147304C (no) 1983-03-16
BG60740B2 (bg) 1996-01-31
NO147304B (no) 1982-12-06

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Free format text: ANDRAE, S., DIPL.-CHEM. DR.RER.NAT., 81541 MUENCHEN FLACH, D., DIPL.-PHYS., 83022 ROSENHEIM HAUG, D., DIPL.-ING. KNEISSL, R., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 81541 MUENCHEN