DD202715A5 - Verfahren zur herstellung von substituierten derivaten des pyridazin - Google Patents

Verfahren zur herstellung von substituierten derivaten des pyridazin Download PDF

Info

Publication number
DD202715A5
DD202715A5 DD82242356A DD24235682A DD202715A5 DD 202715 A5 DD202715 A5 DD 202715A5 DD 82242356 A DD82242356 A DD 82242356A DD 24235682 A DD24235682 A DD 24235682A DD 202715 A5 DD202715 A5 DD 202715A5
Authority
DD
German Democratic Republic
Prior art keywords
group
reaction
hydrogen
pyridazine
carried out
Prior art date
Application number
DD82242356A
Other languages
German (de)
English (en)
Inventor
Jean-Paul Kan
Kathleen Biziere
Camille G Wermuth
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DD202715A5 publication Critical patent/DD202715A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DD82242356A 1981-08-07 1982-08-09 Verfahren zur herstellung von substituierten derivaten des pyridazin DD202715A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8115380A FR2510998B1 (fr) 1981-08-07 1981-08-07 Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent

Publications (1)

Publication Number Publication Date
DD202715A5 true DD202715A5 (de) 1983-09-28

Family

ID=9261294

Family Applications (2)

Application Number Title Priority Date Filing Date
DD82242356A DD202715A5 (de) 1981-08-07 1982-08-09 Verfahren zur herstellung von substituierten derivaten des pyridazin
DD82242359A DD202549A5 (de) 1981-08-07 1982-08-09 Verfahren zur herstellung von pyridazin-aminverbindungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DD82242359A DD202549A5 (de) 1981-08-07 1982-08-09 Verfahren zur herstellung von pyridazin-aminverbindungen

Country Status (30)

Country Link
US (1) US4508720A (ko)
EP (2) EP0072726B1 (ko)
JP (2) JPS5877868A (ko)
KR (2) KR890001569B1 (ko)
AR (2) AR231637A1 (ko)
AT (2) ATE18216T1 (ko)
AU (2) AU548930B2 (ko)
CA (2) CA1174240A (ko)
CS (2) CS229940B2 (ko)
DD (2) DD202715A5 (ko)
DE (2) DE3262671D1 (ko)
DK (2) DK148795C (ko)
EG (2) EG15788A (ko)
ES (2) ES514795A0 (ko)
FI (2) FI72968C (ko)
FR (1) FR2510998B1 (ko)
GR (2) GR76429B (ko)
HU (2) HU190028B (ko)
IE (2) IE53387B1 (ko)
IL (2) IL66408A (ko)
MA (2) MA19560A1 (ko)
NO (2) NO157102C (ko)
NZ (2) NZ201520A (ko)
OA (2) OA07176A (ko)
PH (1) PH18545A (ko)
PL (2) PL137199B1 (ko)
PT (2) PT75350B (ko)
SU (2) SU1140685A3 (ko)
YU (2) YU172082A (ko)
ZA (2) ZA825513B (ko)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
CA1218655A (en) * 1983-01-28 1987-03-03 Kathleen Biziere Process for the preparation of pyridazine derivatives having a psychotropic action
US4628088A (en) * 1984-07-17 1986-12-09 Eli Lilly And Company Preparation of substituted pyridazines
DE3664772D1 (en) * 1985-01-14 1989-09-07 Boehringer Ingelheim Kg 12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use
FR2642754B1 (fr) * 1989-02-07 1991-05-24 Sanofi Sa Nouveaux derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant
FR2642648B1 (fr) * 1989-02-07 1991-06-21 Sanofi Sa Utilisation de derives d'alkyl-5 pyridazine comme medicaments actifs sur le systeme cholinergique
FR2654727B1 (fr) * 1989-11-17 1992-03-27 Sanofi Sa Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
US5461053A (en) * 1989-02-07 1995-10-24 Sanofi Pyridazine derivatives
FR2663326B2 (fr) * 1989-11-17 1992-10-16 Sanofi Sa Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
PT93060B (pt) 1989-02-07 1995-12-29 Sanofi Sa Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem
US5631255A (en) * 1989-02-07 1997-05-20 Sanofi Pyridazine derivatives
FR2665442B1 (fr) * 1990-07-31 1992-12-04 Sanofi Sa Derives d'alkyl-6 pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2676444B1 (fr) * 1991-05-16 1995-03-10 Sanofi Elf Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant.
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
US20030176437A1 (en) * 2001-08-31 2003-09-18 D.M. Watterson Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
ATE420867T1 (de) * 2002-08-13 2009-01-15 Merck Sharp & Dohme Phenylpyridazin derivative als liganden für gaba- rezeptoren
WO2006050389A2 (en) 2004-11-02 2006-05-11 Northwestern University Pyridazine compounds, compositions and methods
WO2006050359A2 (en) * 2004-11-02 2006-05-11 Northwestern University Pyridazine compounds and methods
WO2007127375A2 (en) * 2006-04-28 2007-11-08 Northwestern University Formulations containing pyridazine compounds for treating neuroinflammatory diseases
CA2650711A1 (en) * 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
EP2015751A2 (en) * 2006-04-28 2009-01-21 Northwestern University Salts of pyridazine compounds
RU2555969C1 (ru) * 2014-07-09 2015-07-10 Юлия Алексеевна Щепочкина Керамическая масса для изготовления облицовочной плитки

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives

Also Published As

Publication number Publication date
PH18545A (en) 1985-08-09
FI822747L (fi) 1983-02-08
PL137199B1 (en) 1986-05-31
JPS5877868A (ja) 1983-05-11
PL237809A1 (en) 1983-02-28
AU548930B2 (en) 1986-01-09
FI822748A0 (fi) 1982-08-06
KR880001624B1 (ko) 1988-09-02
IL66409A (en) 1985-09-29
EP0072726A1 (fr) 1983-02-23
CA1179346A (en) 1984-12-11
FI72968C (fi) 1987-08-10
PL130647B1 (en) 1984-08-31
US4508720A (en) 1985-04-02
GR76430B (ko) 1984-08-10
HU189166B (en) 1986-06-30
IL66408A0 (en) 1982-11-30
IL66408A (en) 1985-12-31
OA07176A (fr) 1984-04-30
NO822509L (no) 1983-02-08
AU548931B2 (en) 1986-01-09
DE3262671D1 (en) 1985-04-25
ZA825513B (en) 1983-06-29
IE53387B1 (en) 1988-10-26
CS229941B2 (en) 1984-07-16
DK148795C (da) 1986-03-10
ES8305738A1 (es) 1983-04-16
ES514794A0 (es) 1983-04-16
DK148537B (da) 1985-07-29
CA1174240A (en) 1984-09-11
FR2510998B1 (fr) 1986-01-10
SU1138024A3 (ru) 1985-01-30
YU172082A (en) 1985-03-20
NZ201518A (en) 1985-04-30
ZA825512B (en) 1983-06-29
IE821778L (en) 1983-02-07
KR890001569B1 (ko) 1989-05-08
HU190028B (en) 1986-08-28
FI72969C (fi) 1987-08-10
JPH0459312B2 (ko) 1992-09-21
DK354482A (da) 1983-02-08
PT75351B (fr) 1984-08-01
NO157102B (no) 1987-10-12
NO157861B (no) 1988-02-22
NO822510L (no) 1983-02-08
AR231637A1 (es) 1985-01-31
PT75350A (fr) 1982-08-01
IE53388B1 (en) 1988-10-26
PT75351A (fr) 1982-08-01
NO157861C (no) 1988-06-01
JPS5877867A (ja) 1983-05-11
MA19560A1 (fr) 1983-04-01
NZ201520A (en) 1985-04-30
SU1140685A3 (ru) 1985-02-15
IL66409A0 (en) 1982-11-30
ATE18216T1 (de) 1986-03-15
FI72969B (fi) 1987-04-30
KR840001159A (ko) 1984-03-28
ES8305737A1 (es) 1983-04-16
PL237808A1 (en) 1983-02-28
MA19562A1 (fr) 1983-04-01
KR840001145A (ko) 1984-03-28
AU8655482A (en) 1983-02-10
IE821779L (en) 1983-02-07
DK148537C (da) 1986-01-13
AR231441A1 (es) 1984-11-30
DE3269383D1 (en) 1986-04-03
EG15788A (en) 1986-09-30
FR2510998A1 (fr) 1983-02-11
PT75350B (fr) 1984-08-01
OA07175A (fr) 1984-04-30
FI72968B (fi) 1987-04-30
DK148795B (da) 1985-09-30
DD202549A5 (de) 1983-09-21
EP0074863B1 (fr) 1986-02-26
ATE12227T1 (de) 1985-04-15
NO157102C (no) 1988-01-20
YU171882A (en) 1985-03-20
ES514795A0 (es) 1983-04-16
FI822748L (fi) 1983-02-08
CS229940B2 (en) 1984-07-16
DK354382A (da) 1983-02-08
FI822747A0 (fi) 1982-08-06
AU8655382A (en) 1983-02-10
EP0072726B1 (fr) 1985-03-20
GR76429B (ko) 1984-08-10
EG15747A (en) 1986-06-30
EP0074863A1 (fr) 1983-03-23

Similar Documents

Publication Publication Date Title
DD202715A5 (de) Verfahren zur herstellung von substituierten derivaten des pyridazin
DE1770153C3 (de) Heterocyclische Aminoketone, deren pharmakologisch verträgliche Säureadditionssalze und Verfahren zu ihrer Herstellung
DE2163911B2 (de) 2-Aminomethyl-phenole, Verfahren zur Herstellung derselben und diese enthaltende Arzneimittel
DD213212A5 (de) Verfahren zur herstellung von 4-methyl-6-phenyl-pyridazin-derivaten
DD144763A5 (de) Verfahren zur herstellung von phenethanolaminen
DD215542A5 (de) Verfahren zur herstellung von 4-cyano-pyridazinen
DD202550A5 (de) Verfahren zur herstellung von pyridazin-derivaten
DE1770171B2 (de) 2,2-Dimethyl-7-alkyI-4-<4-pyridyl)-2H-chromen-5-ole, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneipräparate
DE1905765C3 (de) In 3-Stellung substituierte 5- [3-(4-carbamoyl-4piperidino-piperidino)-proprl] -5H-IO111-dihydrodibenz (b^azepine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
DE2631885C2 (de) 1-(4-Phenoxyphenyl)-piperazin-Derivate, ihre Salze, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zubereitungen
DE2656088A1 (de) Neues benzylalkoholderivat und verfahren zu seiner herstellung
DE3438244C2 (ko)
DE2757532A1 (de) N,n'-disubstituiertes cyclisches diamin und verfahren zu dessen herstellung
DE2719607C2 (ko)
DD153550A5 (de) Verfahren zur herstellung von neuer 1,2,4-oxadiazolin-5-on-derivaten
DE3101093C2 (ko)
DE2542791C2 (de) N,N'-Disubstituierte Naphthylacetamidine
DE3121175A1 (de) Erythro-1,2,3-triphenyl-1-pentanon-derivate sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DD209457A5 (de) Verfahren zur herstellung von 4-piperazinyl-4-phenyl-chinazolin-derivaten
DE2166662C3 (de) Dibenzothiazepinderivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
DE2125892C3 (de) 23-Dihydro-S-trifIuormethyl-lH- dibenzo [23 zu 6,7] thiepine [4,5] pyrrole, Verfahren zu ihrer Herstellung und diese enthaltende therapeutsche Präparate
DE2000775B2 (de) Substituierte 1,2,3,4-Tetrahydrobenzothieno [23-c] pyridin-Verbindungen, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitung, die diese Verbindungen enthält
DE2738131A1 (de) Aminoketone, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE69125969T2 (de) Arzneimittel zur Behandlung zentraler neuro-degenerativer Erkrankungen
DE1645901C3 (de) gamma-(4-Alkylp!peridino)-p-fluorbutyrophenone und Verfahren zu ihrer Herstellung