DK354482A - Fremgangsmaade til fremstilling af substituerede pyridazinderivater - Google Patents

Fremgangsmaade til fremstilling af substituerede pyridazinderivater Download PDF

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Publication number
DK354482A
DK354482A DK354482A DK354482A DK354482A DK 354482 A DK354482 A DK 354482A DK 354482 A DK354482 A DK 354482A DK 354482 A DK354482 A DK 354482A DK 354482 A DK354482 A DK 354482A
Authority
DK
Denmark
Prior art keywords
procedure
preparing substituted
pyridazine derivatives
substituted pyridazine
derivatives
Prior art date
Application number
DK354482A
Other languages
English (en)
Other versions
DK148795C (da
DK148795B (da
Inventor
J-P Kan
K Biziere
C G Wermuth
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DK354482A publication Critical patent/DK354482A/da
Publication of DK148795B publication Critical patent/DK148795B/da
Application granted granted Critical
Publication of DK148795C publication Critical patent/DK148795C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK354482A 1981-08-07 1982-08-06 Anologifremgangsmaade til fremstilling af 3-(2-morpholino-ethyl-amino)-5-phenyl-pyridazin eller farmaceutisk acceptable syreadditionssalte deraf DK148795C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8115380 1981-08-07
FR8115380A FR2510998B1 (fr) 1981-08-07 1981-08-07 Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent

Publications (3)

Publication Number Publication Date
DK354482A true DK354482A (da) 1983-02-08
DK148795B DK148795B (da) 1985-09-30
DK148795C DK148795C (da) 1986-03-10

Family

ID=9261294

Family Applications (2)

Application Number Title Priority Date Filing Date
DK354382A DK148537C (da) 1981-08-07 1982-08-06 Analogifremgangsmaade til fremstilling af 3-aminopyridazinforbindelser eller farmaceutisk acceptable salte deraf
DK354482A DK148795C (da) 1981-08-07 1982-08-06 Anologifremgangsmaade til fremstilling af 3-(2-morpholino-ethyl-amino)-5-phenyl-pyridazin eller farmaceutisk acceptable syreadditionssalte deraf

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK354382A DK148537C (da) 1981-08-07 1982-08-06 Analogifremgangsmaade til fremstilling af 3-aminopyridazinforbindelser eller farmaceutisk acceptable salte deraf

Country Status (30)

Country Link
US (1) US4508720A (da)
EP (2) EP0072726B1 (da)
JP (2) JPS5877867A (da)
KR (2) KR890001569B1 (da)
AR (2) AR231441A1 (da)
AT (2) ATE12227T1 (da)
AU (2) AU548930B2 (da)
CA (2) CA1174240A (da)
CS (2) CS229941B2 (da)
DD (2) DD202715A5 (da)
DE (2) DE3269383D1 (da)
DK (2) DK148537C (da)
EG (2) EG15788A (da)
ES (2) ES8305737A1 (da)
FI (2) FI72969C (da)
FR (1) FR2510998B1 (da)
GR (2) GR76429B (da)
HU (2) HU189166B (da)
IE (2) IE53387B1 (da)
IL (2) IL66409A (da)
MA (2) MA19562A1 (da)
NO (2) NO157861C (da)
NZ (2) NZ201520A (da)
OA (2) OA07176A (da)
PH (1) PH18545A (da)
PL (2) PL137199B1 (da)
PT (2) PT75350B (da)
SU (2) SU1138024A3 (da)
YU (2) YU172082A (da)
ZA (2) ZA825512B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
US4565814A (en) * 1983-01-28 1986-01-21 Sanofi Pyridazine derivatives having a psychotropic action and compositions
US4628088A (en) * 1984-07-17 1986-12-09 Eli Lilly And Company Preparation of substituted pyridazines
DE3664772D1 (en) * 1985-01-14 1989-09-07 Boehringer Ingelheim Kg 12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use
FR2654727B1 (fr) * 1989-11-17 1992-03-27 Sanofi Sa Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
US5656631A (en) * 1989-02-07 1997-08-12 Sanofi Pyridazine derivatives
FR2663326B2 (fr) * 1989-11-17 1992-10-16 Sanofi Sa Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2665442B1 (fr) * 1990-07-31 1992-12-04 Sanofi Sa Derives d'alkyl-6 pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2642648B1 (fr) * 1989-02-07 1991-06-21 Sanofi Sa Utilisation de derives d'alkyl-5 pyridazine comme medicaments actifs sur le systeme cholinergique
FR2642754B1 (fr) * 1989-02-07 1991-05-24 Sanofi Sa Nouveaux derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant
US5461053A (en) * 1989-02-07 1995-10-24 Sanofi Pyridazine derivatives
PT93060B (pt) 1989-02-07 1995-12-29 Sanofi Sa Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem
FR2676444B1 (fr) * 1991-05-16 1995-03-10 Sanofi Elf Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant.
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
EP1430033A4 (en) * 2001-08-31 2004-12-15 Univ Northwestern PROTEIN KINASE ANTI-INFLAMMATORY AND INHIBITOR COMPOSITION AND METHOD OF USE
DE60325865D1 (de) * 2002-08-13 2009-03-05 Merck Sharp & Dohme Phenylpyridazin derivative als liganden für gaba-rezeptoren
EP1812007B1 (en) * 2004-11-02 2011-09-07 Northwestern University Pyridazine compounds and methods
CN101087766B (zh) * 2004-11-02 2011-09-07 西北大学 哒嗪化合物、组合物和方法
US20090325973A1 (en) * 2006-04-28 2009-12-31 Watterson D Martin Formulations containing pyridazine compounds
CA2650704A1 (en) * 2006-04-28 2007-11-08 Northwestern University Salts of pyridazine compounds
EP2015750A2 (en) * 2006-04-28 2009-01-21 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
RU2555969C1 (ru) * 2014-07-09 2015-07-10 Юлия Алексеевна Щепочкина Керамическая масса для изготовления облицовочной плитки

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives

Also Published As

Publication number Publication date
IE821778L (en) 1983-02-07
FR2510998B1 (fr) 1986-01-10
FI72968B (fi) 1987-04-30
DK354382A (da) 1983-02-08
FI822748L (fi) 1983-02-08
OA07175A (fr) 1984-04-30
DE3262671D1 (en) 1985-04-25
OA07176A (fr) 1984-04-30
CS229941B2 (en) 1984-07-16
KR840001145A (ko) 1984-03-28
DD202715A5 (de) 1983-09-28
ES514795A0 (es) 1983-04-16
GR76429B (da) 1984-08-10
IL66408A (en) 1985-12-31
IE53387B1 (en) 1988-10-26
KR890001569B1 (ko) 1989-05-08
EP0072726B1 (fr) 1985-03-20
NZ201518A (en) 1985-04-30
AU8655482A (en) 1983-02-10
PL237809A1 (en) 1983-02-28
ZA825512B (en) 1983-06-29
ES8305738A1 (es) 1983-04-16
EG15747A (en) 1986-06-30
JPS5877867A (ja) 1983-05-11
FR2510998A1 (fr) 1983-02-11
NO157102B (no) 1987-10-12
ES514794A0 (es) 1983-04-16
DE3269383D1 (en) 1986-04-03
EG15788A (en) 1986-09-30
FI822748A0 (fi) 1982-08-06
IE821779L (en) 1983-02-07
MA19562A1 (fr) 1983-04-01
NO157861B (no) 1988-02-22
FI822747L (fi) 1983-02-08
ES8305737A1 (es) 1983-04-16
AU548930B2 (en) 1986-01-09
FI822747A0 (fi) 1982-08-06
NO822509L (no) 1983-02-08
NO157861C (no) 1988-06-01
KR840001159A (ko) 1984-03-28
DK148795C (da) 1986-03-10
AU548931B2 (en) 1986-01-09
FI72969B (fi) 1987-04-30
JPH0459312B2 (da) 1992-09-21
NO822510L (no) 1983-02-08
ATE12227T1 (de) 1985-04-15
KR880001624B1 (ko) 1988-09-02
DK148537B (da) 1985-07-29
DK148795B (da) 1985-09-30
US4508720A (en) 1985-04-02
SU1140685A3 (ru) 1985-02-15
HU189166B (en) 1986-06-30
PT75351B (fr) 1984-08-01
ATE18216T1 (de) 1986-03-15
CA1179346A (en) 1984-12-11
HU190028B (en) 1986-08-28
FI72969C (fi) 1987-08-10
EP0074863A1 (fr) 1983-03-23
NO157102C (no) 1988-01-20
YU171882A (en) 1985-03-20
AR231441A1 (es) 1984-11-30
FI72968C (fi) 1987-08-10
EP0072726A1 (fr) 1983-02-23
AU8655382A (en) 1983-02-10
MA19560A1 (fr) 1983-04-01
EP0074863B1 (fr) 1986-02-26
CA1174240A (en) 1984-09-11
GR76430B (da) 1984-08-10
PT75350B (fr) 1984-08-01
PL237808A1 (en) 1983-02-28
AR231637A1 (es) 1985-01-31
IL66409A (en) 1985-09-29
PT75350A (fr) 1982-08-01
DD202549A5 (de) 1983-09-21
PL137199B1 (en) 1986-05-31
DK148537C (da) 1986-01-13
JPS5877868A (ja) 1983-05-11
IE53388B1 (en) 1988-10-26
NZ201520A (en) 1985-04-30
IL66409A0 (en) 1982-11-30
PH18545A (en) 1985-08-09
IL66408A0 (en) 1982-11-30
ZA825513B (en) 1983-06-29
CS229940B2 (en) 1984-07-16
PT75351A (fr) 1982-08-01
SU1138024A3 (ru) 1985-01-30
PL130647B1 (en) 1984-08-31
YU172082A (en) 1985-03-20

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