DK372081A - Fremgangsmaade til fremstilling af fluorerede pentendiaminderivater - Google Patents

Fremgangsmaade til fremstilling af fluorerede pentendiaminderivater

Info

Publication number
DK372081A
DK372081A DK372081A DK372081A DK372081A DK 372081 A DK372081 A DK 372081A DK 372081 A DK372081 A DK 372081A DK 372081 A DK372081 A DK 372081A DK 372081 A DK372081 A DK 372081A
Authority
DK
Denmark
Prior art keywords
pentendiamine
fluored
derivatives
preparing
procedure
Prior art date
Application number
DK372081A
Other languages
English (en)
Other versions
DK152115C (da
DK152115B (da
Inventor
P Bey
F Gerhart
M Jung
Original Assignee
Merrell Toraude & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude & Co filed Critical Merrell Toraude & Co
Publication of DK372081A publication Critical patent/DK372081A/da
Publication of DK152115B publication Critical patent/DK152115B/da
Application granted granted Critical
Publication of DK152115C publication Critical patent/DK152115C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/17—Unsaturated ethers containing halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DK372081A 1980-08-23 1981-08-21 Analogifremgangsmaade til fremstilling af fluorerede 2,5-diamino-3-pentenderivater og farmaceutisk acceptable salte deraf DK152115C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8027519 1980-08-23
GB8027519 1980-08-23
GB8037841 1980-11-26
GB8037841 1980-11-26

Publications (3)

Publication Number Publication Date
DK372081A true DK372081A (da) 1982-02-24
DK152115B DK152115B (da) 1988-02-01
DK152115C DK152115C (da) 1988-06-20

Family

ID=26276683

Family Applications (1)

Application Number Title Priority Date Filing Date
DK372081A DK152115C (da) 1980-08-23 1981-08-21 Analogifremgangsmaade til fremstilling af fluorerede 2,5-diamino-3-pentenderivater og farmaceutisk acceptable salte deraf

Country Status (13)

Country Link
US (1) US4439619A (da)
EP (1) EP0046713B1 (da)
AU (1) AU544262B2 (da)
CA (1) CA1182126A (da)
DE (1) DE3173305D1 (da)
DK (1) DK152115C (da)
ES (1) ES504879A0 (da)
GB (1) GB2083030B (da)
IE (1) IE51511B1 (da)
IL (1) IL63633A (da)
NO (1) NO151196C (da)
NZ (1) NZ198117A (da)
PH (1) PH22945A (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4866206A (en) * 1977-07-11 1989-09-12 Merrell Dow France Et Cie 2-Halomethyl derivatives of 2-amino acids
US5614557A (en) * 1977-07-11 1997-03-25 Marion Merrell Et Compagnie C/O Merrell Pharmaceuticals Inc. Method of controlling tumor growth rate
IE54303B1 (en) * 1981-08-19 1989-08-16 Merrell Dow France Fluorinated diaminoalkene derivatives
US4435425A (en) 1982-04-09 1984-03-06 Merrell Toraude Et Compagnie Fluorinated diaminobutane derivatives
US4629685A (en) * 1984-11-16 1986-12-16 Ciba-Geigy Corporation Process for irradiating polyimides
US5196450A (en) * 1985-12-19 1993-03-23 Merrell Dow Pharmaceuticals Inc. Method of inhibiting protozoal growth
DE3712365A1 (de) * 1987-04-11 1988-10-27 Hoechst Ag Neue 2-acylpyrrolidin-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel sowie deren verwendung
DE3712364A1 (de) * 1987-04-11 1988-10-27 Hoechst Ag Neue pyrrolidin-2-(1,3-dicarbonyl)-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel sowie deren verwendung
US20170273926A1 (en) * 2016-03-24 2017-09-28 Orbus Therapeutics, Inc. Compositions and methods for use of eflornithine and derivatives and analogs thereof to treat cancers, including gliomas

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2662915A (en) * 1952-06-30 1953-12-15 Du Pont Alpha-amino acids containing alpha, fluorinated-alkyl or cycloalkyl groups
US4325961A (en) * 1977-06-01 1982-04-20 Merck & Co., Inc. Fluorinated amino acids
CA1091661A (en) * 1977-07-11 1980-12-16 Philippe Bey .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
US4134918A (en) * 1977-09-06 1979-01-16 Merrell Toraude Et Compagnie Alpha-halomethyl derivatives of amines
US4326071A (en) * 1977-09-28 1982-04-20 Merrell Toraude Et Compagnie Halomethyl derivatives of gamma-aminobutyric acid and related compounds
US4323704A (en) * 1979-06-25 1982-04-06 Merrell Toraude Et Compagnie αAcetylene and α-vinyl derivatives of amino acids
NZ194348A (en) * 1979-07-26 1982-09-14 Merrell Toraude & Co Fluorinated methyl-beta-alanine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
IE51511B1 (en) 1987-01-07
DE3173305D1 (de) 1986-02-06
DK152115C (da) 1988-06-20
AU544262B2 (en) 1985-05-23
EP0046713B1 (en) 1985-12-27
NO151196B (no) 1984-11-19
PH22945A (en) 1989-02-03
US4439619A (en) 1984-03-27
EP0046713A1 (en) 1982-03-03
IL63633A0 (en) 1981-11-30
ES8306992A1 (es) 1983-06-16
NO151196C (no) 1985-02-27
CA1182126A (en) 1985-02-05
IL63633A (en) 1985-05-31
ES504879A0 (es) 1983-06-16
DK152115B (da) 1988-02-01
GB2083030B (en) 1984-03-07
IE811925L (en) 1982-05-23
GB2083030A (en) 1982-03-17
AU7443281A (en) 1982-03-04
NO812841L (no) 1982-02-24
NZ198117A (en) 1985-08-30

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Legal Events

Date Code Title Description
PBP Patent lapsed