FR2654727B1 - Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant. - Google Patents

Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.

Info

Publication number
FR2654727B1
FR2654727B1 FR8915137A FR8915137A FR2654727B1 FR 2654727 B1 FR2654727 B1 FR 2654727B1 FR 8915137 A FR8915137 A FR 8915137A FR 8915137 A FR8915137 A FR 8915137A FR 2654727 B1 FR2654727 B1 FR 2654727B1
Authority
FR
France
Prior art keywords
preparation
same
pharmaceutical compositions
compositions containing
pyridazine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR8915137A
Other languages
English (en)
Other versions
FR2654727A1 (fr
Inventor
Boigegrain Robert
Brodin Roger
Kan Jean Paul
Olliero Dominique
Wermuth Camille Georges
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR8915137A priority Critical patent/FR2654727B1/fr
Priority to FR909007533A priority patent/FR2663326B2/fr
Priority to PT95902A priority patent/PT95902B/pt
Priority to FI905663A priority patent/FI101881B1/fi
Priority to NZ236107A priority patent/NZ236107A/en
Priority to ZA909221A priority patent/ZA909221B/xx
Priority to NO904984A priority patent/NO178967C/no
Priority to AT90403239T priority patent/ATE143010T1/de
Priority to HU907178A priority patent/HU207852B/hu
Priority to DE69028602T priority patent/DE69028602T2/de
Priority to IE414590A priority patent/IE75697B1/en
Priority to AR90318401A priority patent/AR247557A1/es
Priority to ES90403239T priority patent/ES2094146T3/es
Priority to CA002030133A priority patent/CA2030133A1/fr
Priority to EP90403239A priority patent/EP0429344B1/fr
Priority to DK90403239.8T priority patent/DK0429344T3/da
Priority to AU66672/90A priority patent/AU639043B2/en
Priority to JP2312597A priority patent/JPH03170465A/ja
Priority to KR1019900018663A priority patent/KR0164599B1/ko
Priority to IL9638490A priority patent/IL96384A/en
Publication of FR2654727A1 publication Critical patent/FR2654727A1/fr
Application granted granted Critical
Publication of FR2654727B1 publication Critical patent/FR2654727B1/fr
Priority to MX9203714A priority patent/MX9203714A/es
Priority to US07/964,901 priority patent/US5461053A/en
Priority to US08/473,580 priority patent/US5656631A/en
Priority to US08/473,582 priority patent/US5631255A/en
Priority to HU95P/P00450P priority patent/HU211351A9/hu
Priority to GR960403344T priority patent/GR3021933T3/el
Priority to LVP-97-165A priority patent/LV11972B/lv
Priority to HK97102147A priority patent/HK1000597A1/xx
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8915137A 1989-02-07 1989-11-17 Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant. Expired - Fee Related FR2654727B1 (fr)

Priority Applications (28)

Application Number Priority Date Filing Date Title
FR8915137A FR2654727B1 (fr) 1989-11-17 1989-11-17 Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR909007533A FR2663326B2 (fr) 1989-11-17 1990-06-15 Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FI905663A FI101881B1 (fi) 1989-11-17 1990-11-15 Menetelmä 3-aminopyridatsiinijohdannaisten valmistamiseksi, jotka ovat käyttökelpoisia asetyylikoliiniluonteisten reseptorien ligandeina
PT95902A PT95902B (pt) 1989-11-17 1990-11-15 Processo para a preparacao de derivados de piridazina uteis como ligandos dos receptores colinergicos
DK90403239.8T DK0429344T3 (fr) 1989-11-17 1990-11-16
NO904984A NO178967C (no) 1989-11-17 1990-11-16 Analogifremgangsmåte for fremstilling av terapeutisk aktive pyridazin-derivater
AT90403239T ATE143010T1 (de) 1989-11-17 1990-11-16 Pyridazin-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
HU907178A HU207852B (en) 1989-11-17 1990-11-16 Process for producing pyridazine derivatives and pharmaceutical compositions containing them
DE69028602T DE69028602T2 (de) 1989-11-17 1990-11-16 Pyridazin-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
IE414590A IE75697B1 (en) 1989-11-17 1990-11-16 Pyridazine derivatives process for their preparation and pharmaceutical compositions containing them
AR90318401A AR247557A1 (es) 1989-11-17 1990-11-16 Un procedimiento para la obtencion de derivados de la piridazina
ES90403239T ES2094146T3 (es) 1989-11-17 1990-11-16 Derivados de la piridazina, procedimiento de preparacion y composiciones farmaceuticas que los contienen.
CA002030133A CA2030133A1 (fr) 1989-11-17 1990-11-16 Derives de pyridazine, mode d'utilisation et compositions pharmaceutiques contenant lesdits derives
EP90403239A EP0429344B1 (fr) 1989-11-17 1990-11-16 Dérivés de la pyridazine, procédé de préparation et compositions pharmaceutiques en contenant
NZ236107A NZ236107A (en) 1989-11-17 1990-11-16 3 (substituted amino)-6-phenyl (and heterocyclyl)-1,2-diazine derivatives; preparatory processes and pharmaceutical compositions
AU66672/90A AU639043B2 (en) 1989-11-17 1990-11-16 Pyridazine derivatives, process for their preparation and pharmaceutical compositions containing them
JP2312597A JPH03170465A (ja) 1989-11-17 1990-11-16 ピリダジン誘導体、その製造方法及び該誘導体を含有する医薬組成物
ZA909221A ZA909221B (en) 1989-11-17 1990-11-16 Pyridazine derivatives,process for their preparation and pharmaceutical compositions containing them
KR1019900018663A KR0164599B1 (ko) 1989-11-17 1990-11-17 피리다진 유도체 이의 제조방법 및 이것을 함유하는 약학 조성물
IL9638490A IL96384A (en) 1989-11-17 1990-11-18 History of pyridazine, their preparation and pharmaceutical preparations containing them
MX9203714A MX9203714A (es) 1989-11-17 1992-06-29 Derivados de piridazina y composiciones farmaceuticas que los contienen.
US07/964,901 US5461053A (en) 1989-02-07 1992-10-22 Pyridazine derivatives
US08/473,580 US5656631A (en) 1989-02-07 1995-06-07 Pyridazine derivatives
US08/473,582 US5631255A (en) 1989-02-07 1995-06-07 Pyridazine derivatives
HU95P/P00450P HU211351A9 (en) 1989-11-17 1995-06-27 Pyridazine derivatives, process for their preparation and pharmaceutical compositions containing them
GR960403344T GR3021933T3 (en) 1989-11-17 1996-12-06 Pyridazine derivatives, process for their preparation and pharmaceutical compositions containing them
LVP-97-165A LV11972B (lv) 1989-11-17 1997-09-10 Piridazīna atvasinājums, tā iegūšanas paņēmiens un farmaceitiskā kompozīcija
HK97102147A HK1000597A1 (en) 1989-11-17 1997-11-10 Pyridazine derivatives process for their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8915137A FR2654727B1 (fr) 1989-11-17 1989-11-17 Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.

Publications (2)

Publication Number Publication Date
FR2654727A1 FR2654727A1 (fr) 1991-05-24
FR2654727B1 true FR2654727B1 (fr) 1992-03-27

Family

ID=9387521

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8915137A Expired - Fee Related FR2654727B1 (fr) 1989-02-07 1989-11-17 Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.

Country Status (2)

Country Link
FR (1) FR2654727B1 (fr)
ZA (1) ZA909221B (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2510998B1 (fr) * 1981-08-07 1986-01-10 Sanofi Sa Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent

Also Published As

Publication number Publication date
ZA909221B (en) 1991-09-25
FR2654727A1 (fr) 1991-05-24

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ST Notification of lapse