IT8719700A0 - 2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono. - Google Patents

2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono.

Info

Publication number
IT8719700A0
IT8719700A0 IT8719700A IT1970087A IT8719700A0 IT 8719700 A0 IT8719700 A0 IT 8719700A0 IT 8719700 A IT8719700 A IT 8719700A IT 1970087 A IT1970087 A IT 1970087A IT 8719700 A0 IT8719700 A0 IT 8719700A0
Authority
IT
Italy
Prior art keywords
sustituted
thiomethyl
pyridines
contain
preparation
Prior art date
Application number
IT8719700A
Other languages
English (en)
Other versions
IT1204948B (it
Inventor
Carmelo A Gandolfi
Marco Frigerio
Odoardo Tofanetti
Sergio Tognella
Original Assignee
Boheringer Biochemia Robin S P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boheringer Biochemia Robin S P filed Critical Boheringer Biochemia Robin S P
Priority to IT8719700A priority Critical patent/IT1204948B/it
Publication of IT8719700A0 publication Critical patent/IT8719700A0/it
Priority to EP88103777A priority patent/EP0282904B1/en
Priority to AT88103777T priority patent/ATE79870T1/de
Priority to DE8888103777T priority patent/DE3873939D1/de
Priority to JP63058141A priority patent/JPS63243073A/ja
Priority to US07/167,164 priority patent/US4918087A/en
Application granted granted Critical
Publication of IT1204948B publication Critical patent/IT1204948B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT8719700A 1987-03-13 1987-03-13 2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono. IT1204948B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT8719700A IT1204948B (it) 1987-03-13 1987-03-13 2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono.
EP88103777A EP0282904B1 (en) 1987-03-13 1988-03-10 2-thiomethyl-substituted-pyridines, a method for their preparation and pharmaceutical compositions containing them
AT88103777T ATE79870T1 (de) 1987-03-13 1988-03-10 2-thiomethyl-substituierte pyridine, verfahren zu deren herstellung und diese enthaltende arzneimittel.
DE8888103777T DE3873939D1 (de) 1987-03-13 1988-03-10 2-thiomethyl-substituierte pyridine, verfahren zu deren herstellung und diese enthaltende arzneimittel.
JP63058141A JPS63243073A (ja) 1987-03-13 1988-03-11 ２−チオメチル−置換ピリジン、その製造方法、及び該ピリジンを含有する薬剤組成物
US07/167,164 US4918087A (en) 1987-03-13 1988-03-11 2-thiomethyl-substituted-pyridine and -3,5-dicarboxylates having anti-hypertensive activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8719700A IT1204948B (it) 1987-03-13 1987-03-13 2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono.

Publications (2)

Publication Number Publication Date
IT8719700A0 true IT8719700A0 (it) 1987-03-13
IT1204948B IT1204948B (it) 1989-03-10

Family

ID=11160490

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8719700A IT1204948B (it) 1987-03-13 1987-03-13 2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono.

Country Status (6)

Country Link
US (1) US4918087A (it)
EP (1) EP0282904B1 (it)
JP (1) JPS63243073A (it)
AT (1) ATE79870T1 (it)
DE (1) DE3873939D1 (it)
IT (1) IT1204948B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8905526D0 (en) * 1989-03-10 1989-04-19 Fujisawa Pharmaceutical Co N-containing heterocyclic compounds,processes for the preparation thereof and composition comprising the same
ES2065234B1 (es) * 1992-10-27 1995-09-01 Smithkline Beecham Corp Compuestos para tratar enfermedades relacionadas con los leucotrienos.
US5380734A (en) * 1993-04-15 1995-01-10 American Home Products Corporation N-cyanoamidine derivatives as anti-influenza agents
DE4430638A1 (de) * 1994-08-29 1996-03-07 Bayer Ag Verwendung von substituierten 4-Phenyl-6-amino-nicotinsäurederivaten als Arzneimittel
DE19532320A1 (de) * 1995-09-01 1997-03-06 Bayer Ag Verfahren zur Herstellung von optisch aktiven ortho-substituierten 4-Aryl-Dihydropyridinen
WO2000077009A1 (en) * 1999-06-14 2000-12-21 Ortho-Mcneil Pharmaceutical, Inc. DITHIEPINO[6,5-b]PYRIDINES, AND RELATED COMPOSITIONS AND METHODS
DE10115945A1 (de) 2001-03-30 2002-10-02 Bayer Ag Substituierte 2-Carba-3,5-dicyano-4-aryl-6-aminopyridine und ihre Verwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3209274A1 (de) * 1982-03-13 1983-09-15 Bayer Ag, 5090 Leverkusen Pyridincarbonsaeureester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
IL68604A0 (en) * 1982-05-21 1983-09-30 Haessle Ab Processes for preparing therapeutically active dihydropyridines and intermediates for the processes
PT77842B (en) * 1982-12-21 1986-05-05 Pfizer Process for preparing dihydropyridines
IT1201454B (it) * 1985-08-19 1989-02-02 Boehringer Biochemia Srl 1,4-diidropiridine-2-sostituite

Also Published As

Publication number Publication date
EP0282904A2 (en) 1988-09-21
JPS63243073A (ja) 1988-10-07
US4918087A (en) 1990-04-17
ATE79870T1 (de) 1992-09-15
EP0282904B1 (en) 1992-08-26
IT1204948B (it) 1989-03-10
EP0282904A3 (en) 1988-10-05
DE3873939D1 (de) 1992-10-01

Similar Documents

Publication Publication Date Title
IT8322185A0 (it) Nuovi derivati benzotiazepinonici, metodo per la loro preparazione e composizioni farmaceutiche che licontengono.
IT8720619A0 (it) Derivati 1-(idrossistiril)-5h2,3-benzodiazepinici, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
FI881307A7 (fi) Menetelmä sydämeen ja kardiovaskulaariseen järjestelmään vaikuttavien farmaseuttisten koostumusten valmistamiseksi.
IT8719700A0 (it) 2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono.
IT8319027A0 (it) Derivati amino-alchil-solfonici, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
IT8720618A0 (it) Derivati 3-(idrossimetil)isochinolinici, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
IT8522868A0 (it) Derivati tienopiridinici, procedimento per la loro preparazione e composizioni terapeutiche che li contengono.
IT8548964A0 (it) 8alfa-acilamminoergoline,loro preparazione e composizioni farmaceutiche che le contengono
IT8621857A0 (it) Cinnamilammine, processo per laloro preparazione e composizioni farmaceutiche che le contengono.
IT8720728A0 (it) 2-selenometil-1,4-diidropiridine, procedimenti per la loro preparazione e composizioni farmaceutiche che le contengono.
IT8448800A0 (it) Amminociclopentani, composizioni farmaceutiche che li contengono eprocedimento per la loro preparazione
IT8419167A0 (it) Carbostirilossiminopropanolamine utili come medicamenti eprocedimento per la loro preparazione.
IT8520483A0 (it) Derivati di apovincaminolo, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
IT8348518A0 (it) Piperidinoguanidine sostituite,procedimento per la loro preparazione e composizioni farmaceutiche che le contengono
IT8747852A0 (it) Benzammidi sostituite, procedimento per la loro preparazione e composizioni farmaceutiche che le contengono
IT8720179A0 (it) 2-sulfinil-acetil-1,3-tiazolidine, loro preparazione e composizioni farmaceutiche.
IT8820306A0 (it) Tioeteri chinolinici, procedimento per la loro preparazione e composizioni farmaceutiche che licontengono.
IT8522364A0 (it) Derivato diidropiridinico, procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono.
FI852710A7 (fi) Fenyylietyyliaminopropiofenoni -johdannaisia, menetelmiä niiden valmistamiseksi ja näitä sisältäviä lääkeaineita.
FI873192A7 (fi) 1,3-propaanidiamiinijohdannaisia, menetelmä ja farmaseuttisia koostumuksia jotka sisältävät niitä.
IT8721796A0 (it) Nuove 2-aralchil-1,4-diidropiridine, un metodo per la loro preparazione e composizioni farmaceutiche che le contengono.
IT8820468A0 (it) Piridobenzodiazepinoni, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
IT8622880A0 (it) 1,4-diidroipiridine-2-alchil-sostituite, un metodo per la loro preparazione e composizioni farmaceutiche che le contengono.
IT8521876A0 (it) Diidropiridine 2-tiosostituite, metodo per la loro preparazione e composizione farmaceutiche che le contengono.
IT8224085A0 (it) Nuove immine cicliche, loro preparazione e composizioni farmaceutiche che le contengono.