CY2019032I1 - (+)-2-[1-(3-αιθοξυ-4-μεθοξυφαινυλ)-2-μεθυλσουλφονυλαιθυλ]-4-ακετυλαμινoϊσoϊνδoλινo-1,3-διonη: μεθοδοι χρησης και συνθεσεις αυτης - Google Patents
(+)-2-[1-(3-αιθοξυ-4-μεθοξυφαινυλ)-2-μεθυλσουλφονυλαιθυλ]-4-ακετυλαμινoϊσoϊνδoλινo-1,3-διonη: μεθοδοι χρησης και συνθεσεις αυτηςInfo
- Publication number
- CY2019032I1 CY2019032I1 CY2019032C CY2019032C CY2019032I1 CY 2019032 I1 CY2019032 I1 CY 2019032I1 CY 2019032 C CY2019032 C CY 2019032C CY 2019032 C CY2019032 C CY 2019032C CY 2019032 I1 CY2019032 I1 CY 2019032I1
- Authority
- CY
- Cyprus
- Prior art keywords
- acetylaminoisoindoline
- methylsulphonylethyl
- dione
- methoxyphenyl
- ethoxy
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- IMOZEMNVLZVGJZ-UHFFFAOYSA-N n-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide Chemical compound C1=C(OC)C(OCC)=CC(C(CS(C)(=O)=O)N2C(C3=C(NC(C)=O)C=CC=C3C2=O)=O)=C1 IMOZEMNVLZVGJZ-UHFFFAOYSA-N 0.000 title 1
Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36651502P | 2002-03-20 | 2002-03-20 | |
US43845003P | 2003-01-07 | 2003-01-07 | |
EP03721414A EP1485087B1 (en) | 2002-03-20 | 2003-03-20 | (+)-2- [1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione for use in treating psoriasis by oral administration |
PCT/US2003/008738 WO2003080049A1 (en) | 2002-03-20 | 2003-03-20 | (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof |
EP09003138.6A EP2074995B1 (en) | 2002-03-20 | 2003-03-20 | (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof |
Publications (2)
Publication Number | Publication Date |
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CY2019032I1 true CY2019032I1 (el) | 2020-05-29 |
CY2019032I2 CY2019032I2 (el) | 2020-05-29 |
Family
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Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
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CY20091100967T CY1109380T1 (el) | 2002-03-20 | 2009-09-18 | (+)-2-[1-(3-αιθοξυ-4-μεθοξυφαινυλο)-2-μεθυλοσουλφονυλαιθυλο]-4-ακετυλαμινοϊσονδολινο-1,3-διονη για χρηση στην αντιμετωπιση ψωριασης μεσω στοματικης χορηγησης |
CY20171100748T CY1119204T1 (el) | 2002-03-20 | 2017-07-14 | (+)-2-[1-(3-αιθοξυ-4-μεθοξυφαινυλο)-2-μεθυλοσουλφονυλαιθυλο]-4-ακετυλαμινοϊσονδολινο-1,3-διονη: μεθοδοι χρησης και συνθεσεις αυτης |
CY20171100884T CY1119340T1 (el) | 2002-03-20 | 2017-08-21 | (+)-2-[1-(3-αιθοξυ-4-μεθοξυφαινυλο)-2-μεθυλοσουλφονυλαιθυλο]-4-ακετυλαμινοϊσονδολινο-1,3-διονη: μεθοδοι χρησης και συνθεσεις αυτης |
CY20191100372T CY1121720T1 (el) | 2002-03-20 | 2019-04-03 | (+)-2-[1-(3-αιθοξυ-4-μεθοξυφαινυλ)-2-μεθυλσουλφονυλαιθυλ]-4-ακετυλαμινoϊσoϊνδoλινo-1,3-διonη: μεθοδοι χρησης και συνθεσεις αυτης |
CY2019032C CY2019032I2 (el) | 2002-03-20 | 2019-06-18 | (+)-2-[1-(3-αιθοξυ-4-μεθοξυφαινυλ)-2-μεθυλσουλφονυλαιθυλ]-4-ακετυλαμινoϊσoϊνδoλινo-1,3-διonη: μεθοδοι χρησης και συνθεσεις αυτης |
CY20191100877T CY1121888T1 (el) | 2002-03-20 | 2019-08-14 | (+)-2-[1-(3-αιθοξυ-4-μεθοξυφαινυλ)-2-μεθυλοσουλφονυλαιθυλ]-4-ακετυλαμινοϊσοϊνδολινο-1,3-διονη: μεθοδοι χρησης και συνθεσεις αυτης |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
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CY20091100967T CY1109380T1 (el) | 2002-03-20 | 2009-09-18 | (+)-2-[1-(3-αιθοξυ-4-μεθοξυφαινυλο)-2-μεθυλοσουλφονυλαιθυλο]-4-ακετυλαμινοϊσονδολινο-1,3-διονη για χρηση στην αντιμετωπιση ψωριασης μεσω στοματικης χορηγησης |
CY20171100748T CY1119204T1 (el) | 2002-03-20 | 2017-07-14 | (+)-2-[1-(3-αιθοξυ-4-μεθοξυφαινυλο)-2-μεθυλοσουλφονυλαιθυλο]-4-ακετυλαμινοϊσονδολινο-1,3-διονη: μεθοδοι χρησης και συνθεσεις αυτης |
CY20171100884T CY1119340T1 (el) | 2002-03-20 | 2017-08-21 | (+)-2-[1-(3-αιθοξυ-4-μεθοξυφαινυλο)-2-μεθυλοσουλφονυλαιθυλο]-4-ακετυλαμινοϊσονδολινο-1,3-διονη: μεθοδοι χρησης και συνθεσεις αυτης |
CY20191100372T CY1121720T1 (el) | 2002-03-20 | 2019-04-03 | (+)-2-[1-(3-αιθοξυ-4-μεθοξυφαινυλ)-2-μεθυλσουλφονυλαιθυλ]-4-ακετυλαμινoϊσoϊνδoλινo-1,3-διonη: μεθοδοι χρησης και συνθεσεις αυτης |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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CY20191100877T CY1121888T1 (el) | 2002-03-20 | 2019-08-14 | (+)-2-[1-(3-αιθοξυ-4-μεθοξυφαινυλ)-2-μεθυλοσουλφονυλαιθυλ]-4-ακετυλαμινοϊσοϊνδολινο-1,3-διονη: μεθοδοι χρησης και συνθεσεις αυτης |
Country Status (24)
Country | Link |
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US (14) | US6962940B2 (el) |
EP (9) | EP2962690B1 (el) |
JP (4) | JP2005525386A (el) |
KR (6) | KR100997001B1 (el) |
CN (2) | CN100427085C (el) |
AT (1) | ATE440599T1 (el) |
AU (1) | AU2003224729C9 (el) |
BE (1) | BE2019C008I2 (el) |
CA (2) | CA2479666C (el) |
CY (6) | CY1109380T1 (el) |
DE (1) | DE60328974D1 (el) |
DK (6) | DK1485087T3 (el) |
ES (8) | ES2717517T3 (el) |
FR (1) | FR19C1046I2 (el) |
HK (3) | HK1073426A1 (el) |
HU (5) | HUE034348T2 (el) |
IL (3) | IL164147A0 (el) |
LU (1) | LUC00125I2 (el) |
MX (2) | MXPA04009075A (el) |
NL (1) | NL300994I2 (el) |
NZ (1) | NZ535798A (el) |
PT (6) | PT2962690T (el) |
SI (5) | SI1485087T1 (el) |
WO (1) | WO2003080049A1 (el) |
Families Citing this family (148)
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WO1998006692A1 (en) * | 1996-08-12 | 1998-02-19 | Celgene Corporation | Novel immunotherapeutic agents and their use in the reduction of cytokine levels |
US8030343B2 (en) * | 2000-06-08 | 2011-10-04 | Celgene Corporation | Pharmaceutically active isoindoline derivatives |
US6962940B2 (en) | 2002-03-20 | 2005-11-08 | Celgene Corporation | (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof |
US7276529B2 (en) * | 2002-03-20 | 2007-10-02 | Celgene Corporation | Methods of the treatment or prevention of exercise-induced asthma using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione |
US7893101B2 (en) * | 2002-03-20 | 2011-02-22 | Celgene Corporation | Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof |
CA2379887C (en) * | 2002-04-09 | 2004-01-20 | Bernard Charles Sherman | Stable tablets comprising simvastatin |
US20100129363A1 (en) * | 2002-05-17 | 2010-05-27 | Zeldis Jerome B | Methods and compositions using pde4 inhibitors for the treatment and management of cancers |
NZ570777A (en) * | 2002-05-17 | 2009-04-30 | Celgene Corp | Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases |
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2014
- 2014-06-26 US US14/316,160 patent/US9283207B2/en not_active Expired - Fee Related
- 2014-09-18 JP JP2014190477A patent/JP2015013893A/ja active Pending
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2016
- 2016-02-05 US US15/016,856 patent/US9724330B2/en not_active Expired - Lifetime
- 2016-06-20 HK HK16107088.0A patent/HK1219049A1/zh not_active IP Right Cessation
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2017
- 2017-06-21 US US15/629,678 patent/US10092542B2/en not_active Expired - Lifetime
- 2017-07-14 CY CY20171100748T patent/CY1119204T1/el unknown
- 2017-08-21 CY CY20171100884T patent/CY1119340T1/el unknown
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2018
- 2018-09-07 US US16/125,571 patent/US10610516B2/en not_active Expired - Fee Related
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2019
- 2019-04-03 CY CY20191100372T patent/CY1121720T1/el unknown
- 2019-06-14 LU LU00125C patent/LUC00125I2/fr unknown
- 2019-06-18 HU HUS1900032C patent/HUS1900032I1/hu unknown
- 2019-06-18 BE BE2019C008C patent/BE2019C008I2/nl unknown
- 2019-06-18 NL NL300994C patent/NL300994I2/nl unknown
- 2019-06-18 CY CY2019032C patent/CY2019032I2/el unknown
- 2019-07-12 FR FR19C1046C patent/FR19C1046I2/fr active Active
- 2019-08-14 CY CY20191100877T patent/CY1121888T1/el unknown
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2020
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