CN105358194B - 注射装置 - Google Patents
注射装置 Download PDFInfo
- Publication number
- CN105358194B CN105358194B CN201480033329.6A CN201480033329A CN105358194B CN 105358194 B CN105358194 B CN 105358194B CN 201480033329 A CN201480033329 A CN 201480033329A CN 105358194 B CN105358194 B CN 105358194B
- Authority
- CN
- China
- Prior art keywords
- injection device
- locking mechanism
- actuator
- substance
- indicator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31586—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by rotationally moving or pivoted actuator, e.g. an injection lever or handle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
- A61M5/3204—Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2006—Having specific accessories
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/206—With automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
- A61M2005/208—Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/3245—Constructional features thereof, e.g. to improve manipulation or functioning
- A61M2005/3247—Means to impede repositioning of protection sleeve from needle covering to needle uncovering position
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
- A61M2005/3267—Biased sleeves where the needle is uncovered by insertion of the needle into a patient's body
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Electrical Control Of Air Or Fuel Supplied To Internal-Combustion Engine (AREA)
- Fuel-Injection Apparatus (AREA)
- Injection Moulding Of Plastics Or The Like (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
- Polarising Elements (AREA)
Abstract
本发明公开了一种注射装置(110)，所述注射装置包括：致动器(710)，该致动器适于在被致动时使注射序列开始；锁定机构，该锁定机构适于在锁定位置和解锁位置之间运动，在锁定位置，锁定机构防止致动器被致动，在解锁位置，致动器可被致动以使注射序列开始。指示器(570)被构造成能够提供锁定机构是处于其锁定位置还是处于其解锁位置的视觉指示。
Description
技术领域
本发明涉及用于递送注射剂的注射装置，以及注射套件和操作该注射装置的方法。
背景技术
自动注射器可从WO 95/35126和EP-A-0 516 473得知并且往往采用驱动弹簧和某一形式的释放机构，一旦假定注射器的内容已排出，所述释放机构便释放注射器使其不受该驱动弹簧的影响，以允许其通过复位弹簧缩回。
自动注射器可从WO 2007/036676得知，该自动注射器具有在可启动释放机构之前必须脱离的锁定机构。例如当移除夹紧覆盖注射器针头的罩的帽盖时，该锁定机构还在其锁定位置防止注射器克服复位弹簧的偏置而向前运动离开注射装置。在WO 2007/036676中所述的注射装置中，该锁定机构包括从该注射装置的开口端突起的套筒。该套筒通过有有回弹力的弹簧机构偏置到其延伸位置，必须克服此偏置以使该锁定机构脱离。该锁定机构可通过例如使该滑动套筒向内运动到该注射装置中(即，使该套筒缩回)而脱离。这可通过将该滑动套筒的端部压到组织上然后启动该释放机构来完成。
已发现，注射装置诸如WO2007/036676中所述的那些注射装置的用户难以分辩滑动套筒何时已充分缩回以便允许启动所述装置。这对用户来说可能极其令人沮丧，因为他们在启动注射时由于不知道该滑动套筒尚未完全缩回而可能作出无数不成功的尝试。此外，沮丧的用户可能尝试强力推动该注射装置(即，通过向触发器施加过度压力)，并且因此损坏该注射机构。
因此，需要提供如下注射装置：其告知用户关于该注射装置从锁定状态到可执行注射的状态的进度。本发明解决此问题。
发明内容
本发明的第一方面提供一种注射装置，该注射装置包括：致动器，该致动器适于在被致动时使注射序列开始；锁定机构，该锁定机构适于在锁定位置和解锁位置之间运动，在锁定位置，该锁定机构防止该致动器被致动，在解锁位置，该致动器可被致动以使该注射序列开始；和指示器，该指示器被构造成能够提供该锁定机构是处于其锁定位置还是处于其解锁位置的视觉指示。
该指示器允许用户目视检查该锁定机构的状态，从而分辩该致动器是否可致动。因此，用户不再需要认为或假定在尝试运动该锁定机构之后该锁定机构处于其解锁状态，而是可获得该事实的视觉确认，或者了解需要更多努力才能致动该致动器。已发现这令用户舒适，特别是那些可能操作具有此类安全特征结构的注射装置有困难的不灵活的用户。
该指示器可包括位于指示器上的指示器部件，当锁定机构在其锁定位置和解锁位置之间运动时，该指示器部件随锁定机构一起运动。在简单制造的具体实施中，该指示器可形成与该锁定机构相同的部件的一部分。因此，不需要额外部件。此外，该指示器正确发挥作用(即，其中关于该锁定机构是否处于解锁状态的指示正确)的概率最大化，因为其不受制于外部公差，而是与该锁定机构的进度直接相关。另选地，该注射装置可包括独立滑动部件，该滑动部件形成指示器，并且锁定机构直接或经由一个或多个额外部件作用于该滑动部件。这是有利的，因为该独立滑动部件可专门设计成最大化该部件的可视性，并且因此不受制于锁定机构的设计约束。
该注射装置还可包括外壳，该致动器和锁定机构可运动地安装至外壳。该外壳可包括指示器孔以便于目视检查该指示器。这允许将指示器的部件容纳在注射装置内部，从而保护部件免受损害或损坏。
优选地，当锁定机构处于其锁定位置时，指示器部件的至少一部分或全部可通过该指示器孔看见。一方面，该孔可能极大，使得锁定机构的大部分可见，并且该指示器可以是锁定机构上的简单标记，其进度可由用户通过该孔监测。在这种情况下，用户可看到，该注射装置能够例如在该标记与该外壳上的另一标记对准时被致动。另一方面，该孔可能相对较小，并且该指示器可能仅是该锁定机构自身的特定部分，例如颜色明显不同于该机构的其余部分的特定部分。在这种情况下，用户可看到，该注射装置能够在该孔完全充满该不同颜色时被致动。
当然，应当了解，有颜色的部分仅是本发明中提供视觉指示器的一种方式。该指示可提供由以下提供：与不同状态对应的的具有不同颜色的一个或多个区段；颜色梯度(例如红色过渡到绿色)；该指示器上对应于不同状态的一个或多个符号、字符或图像、或技术人员将想到的任何其他方式。
指示器和指示器孔之间的关系可以各种方式实现，如下文所述。
当该锁定机构处于其锁定位置时，该指示器孔可被指示器部件的至少一部分完全覆盖。当该锁定机构不处于其锁定位置时，该指示器孔的至少一部分可不被指示器部件覆盖。
此外，当该锁定机构处于其解锁位置时，指示器部件的至少一部分或全部可通过该指示器孔看见。
另选地，当该锁定机构处于其解锁位置时，该指示器孔可被指示器部件的至少一部分完全覆盖。当该锁定机构不处于其解锁位置时，该指示器孔的至少一部分可不被指示器部件覆盖。
该锁定机构可包括接触部分，该接触部分适于在该锁定机构处于其锁定位置时接触致动器的接合表面。因此，提供阻挡致动器的物理屏障，这防止该致动器在锁定机构处于其锁定位置时被意外致动。该接触部分可适于在该锁定机构处于其解锁位置时不接触该致动器的接合表面。例如，当该锁定机构处于其解锁位置时，该物理屏障可被完全移除而不会干扰该致动器。
在特别优选的实施例中，该锁定机构可在其锁定位置和其解锁位置之间运动，使得该接触部分从其接触该致动器的接合表面的位置运动到其不再接触该致动器的接合表面的位置。
该致动器可被构造成能够在防止该注射序列开始的第一位置和发生该注射序列开始的第二位置之间运动。该致动器可围绕枢轴在其第一位置和第二位置之间旋转。
在本发明的某些实施例中，该注射装置还包括驱动机构。在此类实施例中，该致动器可包括锁定表面，当致动器处于其第一位置时，该锁定表面抑制驱动机构；并且当该驱动机构处于其第二位置时，该锁定表面不抑制驱动机构。
优选地，该注射装置还包括注射器，该注射器可在注射序列开始时由驱动机构从注射器完全容纳在注射装置主体内的位置运动到注射器的针头经由注射开口从注射装置的外壳延伸的位置，其中驱动机构适于在注射器处于其延伸位置时经由针头排出注射器的内容物。自然地，注射器仅是优选的，并且还可提供用于容纳并排出药剂的其他构件，例如带有或不带整体针头或套管的药水瓶或安瓿。
优选地，锁定机构包括滑动部件，该滑动部件滑动以使锁定机构在其锁定位置和解锁位置之间运动。该滑动部件可被构造成能够向内滑动到注射装置中以将其从其锁定位置运动到其解锁位置。
当滑动部件处于其解锁位置时，滑动部件可从外壳中的滑动部件开口(通常但不一定为注射开口)突出。因此，该滑动部件可接合用户的皮肤，并且在用户朝向皮肤推动注射装置时向内运动到注射装置的外壳中。在优选实施例中，滑动部件为滑动套筒。
在任一实施例中，注射装置可包含选自由以下项组成的组的物质：戈利木单抗、激素、抗毒素、用于控制疼痛的物质、用于控制血栓的物质、用于控制或消除感染的物质、肽、蛋白质、人胰岛素或人胰岛素类似物或衍生物、多糖、DNA、RNA、酶、抗体、寡核苷酸、抗过敏药、抗组胺药、抗炎药、皮质类固醇、改善病情抗风湿药、促红细胞生成素、或疫苗，以用于治疗或预防类风湿性关节炎、牛皮癣关节炎、强直性脊柱炎、溃疡性结肠炎、激素缺乏症、中毒、疼痛、血栓、感染、糖尿病、糖尿病性视网膜病、急性冠脉综合征、心绞痛、心肌梗死、动脉粥样硬化、恶性肿瘤、黄斑变性、过敏症、花粉病、炎症、贫血或脊髓发育不良、或用于表达保护性免疫。
所谓“注射装置可容纳物质”是指，该物质可被容纳在注射装置内的合适的药剂容器(例如药水瓶或注射器)内。此药剂容器可容纳其他物质，诸如另外的活性成分或非活性成分。
在本发明的另一方面，通过使用根据上述任一实施例所述的注射装置将物质递送至人类受治疗者来提供所述物质以用于治疗或预防类风湿性关节炎、牛皮癣关节炎、强直性脊柱炎、溃疡性结肠炎、激素缺乏症、中毒、疼痛、血栓、感染、糖尿病、糖尿病性视网膜病、急性冠脉综合征、心绞痛、心肌梗死、动脉粥样硬化、恶性肿瘤、黄斑变性、过敏症、花粉病、炎症、贫血或脊髓发育不良、或用于表达保护性免疫，所述物质选自戈利木单抗、激素、抗毒素、用于控制疼痛的物质、用于控制血栓的物质、用于控制或消除感染的物质、肽、蛋白质、人胰岛素或人胰岛素类似物或衍生物、多糖、DNA、RNA、酶、抗体、寡核苷酸、抗过敏药、抗组胺药、抗炎药、皮质类固醇、改善病情抗风湿药、促红细胞生成素、或疫苗。
在本发明的另一方面，提供一种注射装置，通过使用该注射装置将选自戈利木单抗、激素、抗毒素、用于控制疼痛的物质、用于控制血栓的物质、用于控制或消除感染的物质、肽、蛋白质、人胰岛素或人胰岛素类似物或衍生物、多糖、DNA、RNA、酶、抗体、寡核苷酸、抗过敏药、抗组胺药、抗炎药、皮质类固醇、改善病情抗风湿药、促红细胞生成素、或疫苗的物质递送至人类受治疗者以用于治疗或预防类风湿性关节炎、牛皮癣关节炎、强直性脊柱炎、溃疡性结肠炎、激素缺乏症、中毒、疼痛、血栓、感染、糖尿病、糖尿病性视网膜病、急性冠脉综合征、心绞痛、心肌梗死、动脉粥样硬化、恶性肿瘤、黄斑变性、过敏症、花粉病、炎症、贫血或脊髓发育不良、或用于表达保护性免疫，其中所述注射装置是上述任一实施例所述的注射装置。
所谓“递送物质”是指，该注射装置用于将所述物质注射到人类受治疗者体内，例如通过皮下注射、皮内注射或肌肉注射。可结合其他物质诸如另外的活性成分或非活性成分来施用所述物质。
附图说明
现在结合附图以举例方式描述本发明，其中：
图1示出示例性注射装置，其显示外壳内的机构；
图2示出本发明的注射装置的平面图；
图3示出本发明的注射装置的释放机构的细节；
图4示出本发明注射装置的释放机构的部分的详细视图；
图5示出本发明的注射装置的第一实施例；
图6示出本发明的注射装置的第二实施例；
图7示出本发明的注射装置的第三实施例；
图8a和图8b更详细地示出处于锁定位置和解锁位置的图7中的实施例的指示器；
图9更详细地示出图7的实施例的内部机构；
图10更详细地示出图5的实施例的内部机构；
图11示出示例性注射装置的框架元件；
图12示出图10的实施例的框架元件；并且
图13至图15示出图10中所示内部机构的替代实施例。
具体实施方式
在图1和图2中示出示例性注射装置110。注射装置110具有注射装置外壳112和纵向轴线101。图1和图2仅示出外壳112的下半部分。外壳112的上半部分不存在，以便可清楚地看见内部机构。
注射器(未示出)容纳在外壳112中。注射装置110包括触发器114作为启动装置的一部分。触发器114可围绕枢轴115从静止位置(如图2中所示)旋转到活动位置。触发器114的近侧端部114b与驱动联接装置121连接，驱动弹簧120作用于驱动联接装置121。驱动联接装置121与该注射器连通。驱动联接装置和驱动弹簧全部形成该启动装置的一部分，其通过作用于该注射器而允许递送注射剂。
注射装置110包括释放机构126，该释放机构呈圆柱形套筒形式，该圆柱形套筒从注射装置110的远侧端部突起。
为实现注射剂的递送，触发器114沿方向R围绕枢轴115旋转(即，在其第一端部114a处向下进入外壳112中)。此导致触发器114的第二端部114b从驱动联接装置121脱离，从而允许驱动弹簧120沿纵向轴线101驱动注射器122(经由驱动联接装置121)并且离开外壳112中的孔118。
然而，当释放机构126处于其阻碍位置时(此对应于该释放机构从外壳112的远侧端部突起)，呈突起154(如图3中示出)形式的阻碍物定位成邻接触发器114的部分150的下表面。以此方式，突起154阻碍该触发器的旋转，从而阻碍注射剂的递送。为进行注射，释放机构运动到第二位置，此对应于释放机构126沿纵向轴线101的方向运动到外壳112中。当释放机构处于其第二位置时，突起154与触发器114中的切口152对准。突起154可接收在切口152中，并且因此触发器可围绕枢轴115旋转，并且可实现注射剂的递送。
释放机构包括从滑动套筒126朝近侧延伸的框架116。突起154从框架116的近侧部分径向向外延伸。该框架被构造成能够将滑动套筒部分126(其在该装置的最远侧端部处接合用户的皮肤)联接到该突起。其借助两个朝近侧延伸的腿这样做，从而使用尽可能少的多余材料以防止浪费并避免干扰该注射装置的其他部件。因此，该框架很大程度上是打开的。
现转向图5，显示根据本发明的注射装置500的第一实施例。与上述示例性注射装置一样，注射装置500包括具有壳鼻504的外壳502和滑动套筒506，滑动套筒506被构造成能够接合用户的皮肤从而在装置的外壳502内朝近侧推动。如上所述，该滑动套筒可从滑动套筒防止致动器(例如触发器)启动的锁定位置运动到滑动套筒不防止致动器(例如触发器)启动的解锁位置。
外壳的壳鼻包括孔508，用户可通过孔508观察以目视检查该锁定机构—在此情况下为滑动套筒506部分。该孔可以是孔穴，或者可以是透明材料或半透明材料。滑动套筒通过孔508可见。因此，该滑动套筒充当该用户的关于滑动套筒状态的指示器。例如，当该滑动套筒处于锁定位置时，该指示器将显示一种情形，并且当该滑动套筒处于解锁位置时，该指示器将显示另一种情形。下文更详细地对此进行描述。
图6中示出了根据本发明的注射装置600的第二实施例。相似参考编号示出关于图5的对应特征。同样，外壳604包括孔608。通过孔608，用户可观察以目视检查该锁定机构。然而，就此实施例而言，该孔不位于壳鼻604中，而是在外壳602的主体中。孔608相对于致动器(即触发器)径向偏移，以便能容易地了解何时以优选方式保持该注射装置。
图7中示出了根据本发明的注射装置700的第三实施例。相似参考编号示出关于图5和图6的对应特征。同样，外壳704包括孔708，通过孔708，用户可观察以目视检查该锁定机构。然而，就此实施例而言，该孔位于外壳702的主体中，但与致动器(即触发器)710径向对准。将孔708定位在该外壳的此部分处使得容易了解何时以替代方式保持该注射装置，并且还允许方便地对部件进行内部布置，如下文更详细地描述。
图8a、图8b、图9和图10示出了在使用中的本发明的第三实施例。具体地，图8a示出当该锁定机构处于锁定位置时通过孔708的视觉指示器。图8b示出当该锁定机构处于解锁位置时通过孔708的视觉指示器。如图可见，该视觉指示器的外观已改变，指示该锁定机构处于解锁位置。
图9更详细地示出图7的实施例的内部机构。从图中可以看出，锁定机构提供突起754从其延伸的框架716。如上文结合图1至图4所述，该突起在锁定位置中接合致动器(即，触发器714)，从而防止该致动器被致动。更详细地，致动器714包括延伸部分760，其从触发器714的远侧端部朝远侧延伸。该延伸部分包括切口762和接片764。在锁定位置中，延伸部分760接合接片764。在解锁位置中，延伸部分760接合切口762。
还可以看出，与该致动器径向对准的孔708位于延伸部分760的区域中，并且位于切口762正上方。因此，当锁定机构处于锁定位置时，锁定机构(具体地，延伸部分)由于接合接片而不可见。然而，当锁定机构处于解锁位置并且接合切口时，锁定机构(具体地，延伸部分)通过孔可见。因此，锁定机构自身的一部分充当该锁定机构状态的视觉指示器。使锁定机构(具体地，延伸部分)具有不同的颜色，从而该视觉指示器甚至更有效。
图10更详细地示出图5的实施例的内部机构。除了添加额外指示器接片570以外，锁定机构和致动器与图9中所示的锁定机构和致动器相同，下文更详细地论述。
孔508位于外壳的壳鼻部分中；即，不在延伸部分560的区域中。因此，指示器接片570设置在壳鼻区域中的锁定机构上。当锁定机构处于锁定位置时，锁定机构(具体地，指示器接片570)因其不与孔508成直线而不可见。然而，当锁定机构处于解锁位置时，锁定机构(具体地，指示器接片570)运动成与孔508成直线并因而通过该孔可见。因此，同样地，锁定机构自身的一部分充当该锁定机构状态的视觉指示器。同样，使锁定机构(具体地，延伸部分)具有不同的颜色，从而该视觉指示器甚至更有效。
图11示出用于示例性注射装置的框架元件1116。图12示出用于图10的注射装置的框架元件1216。如图可见，框架元件1216包括其远侧端部处的指示器接片516。指示器接片516包括其中有切口的环形材料带。
图13和图14示出可与注射装置的壳鼻部分中的孔一起使用的替代框架元件1316。图15a和图15b示出在使用中的替代性框架元件，其中该框架元件可运动成与壳鼻中的孔对准和不对准。
技术人员将了解，以上实施例也可以其他方式实施；即，该锁定机构可被构造成能够当其处于锁定位置时与孔成直线并且当处于解锁位置时运动成不与孔成直线。根据孔的特定位置和框架元件、延伸部分或指示器接片的特定构造，该装置可向用户指示，当指示器孔被指示器部件的至少一部分完全覆盖时，该锁定机构处于锁定位置；当指示器孔的至少一部分不被指示器部件覆盖时，该锁定机构不处于其锁定位置。另选地，该装置可向用户指示：当指示器孔被指示器部件的至少一部分完全覆盖时，该锁定机构处于解锁位置；当指示器孔的至少一部分不被指示器部件覆盖时，该锁定机构不处于其解锁位置。
此外，技术人员将了解，该锁定机构可提供为单个整体模制的部件，或提供为独立部件。例如，这些框架元件可与滑动套筒分离或机械联接到滑动套筒，或者可提供为单个整体部件。
在使用中，如上所述的此类注射装置可用于递送如下物质，诸如：戈利木单抗、激素、抗毒素、用于控制疼痛的物质、用于控制血栓的物质、用于控制或消除感染的物质、肽、蛋白质、人胰岛素或人胰岛素类似物或衍生物、多糖、DNA、RNA、酶、抗体、寡核苷酸、抗过敏药、抗组胺药、抗炎药、皮质类固醇、改善病情抗风湿药、促红细胞生成素、或疫苗，以用于治疗或预防类风湿性关节炎、牛皮癣关节炎、强直性脊柱炎、溃疡性结肠炎、激素缺乏症、中毒、疼痛、血栓、感染、糖尿病、糖尿病性视网膜病、急性冠脉综合征、心绞痛、心肌梗死、动脉粥样硬化、恶性肿瘤、黄斑变性、过敏症、花粉病、炎症、贫血或脊髓发育不良、或用于表达保护性免疫。除这些物质以外，该注射装置内容纳的任何药剂还可包含其他物质，例如非活性成分，如技术人员将了解的。
当然，技术人员应当理解，特定物质有效用于治疗或预防如本领域中熟知的特定症状。例如，已知抗过敏药有效用于治疗或预防过敏；抗组胺药有效用于治疗或预防花粉病；抗炎药有效用于治疗或预防炎症等等。因此，设想任意选择本文中或权利要求中所列出的一种或多种物质，以用于治疗或预防已知那些物质针对其有效的一种或多种症状。
然而，在特定实例中，戈利木单抗已知有效用于治疗或预防类风湿性关节炎、牛皮癣关节炎、强直性脊柱炎或溃疡性结肠炎中的一者或多者，或者类风湿性关节炎、牛皮癣关节炎、强直性脊柱炎和溃疡性结肠炎的任意组合，或者类风湿性关节炎、牛皮癣关节炎、强直性脊柱炎和溃疡性结肠炎的全部。
戈利木单抗可任选地结合一种或多种非活性成分诸如L-组氨酸、L-组氨酸盐酸盐水合物、山梨醇、聚山梨酸酯80和水中的任一者或全部来使用。戈利木单抗可存在于其中戈利木单抗是唯一活性成分的组合物中。例如，戈利木单抗可以给药。
当然，应当理解，上文已仅以举例方式描述了本发明，并且可在本发明的范围内作出对细节的修改。
Claims (18)
1.一种注射装置，包括：
致动器，所述致动器适于在被致动时使注射序列开始；
锁定机构，所述锁定机构适于在锁定位置和解锁位置之间运动，在所述锁定位置，所述锁定机构防止所述致动器被致动，在所述解锁位置，所述致动器能够被致动以使所述注射序列开始，其中所述锁定机构包括滑动部件，所述滑动部件滑动以使所述锁定机构在其锁定位置和解锁位置之间运动，其中所述滑动部件被构造成能够向内滑动到所述注射装置中以使所述滑动部件从其锁定位置运动到其解锁位置；
外壳，所述致动器和所述锁定机构可运动地安装至所述外壳；
指示器，所述指示器被构造成能够提供所述锁定机构是处于其锁定位置还是处于其解锁位置的视觉指示，其中所述指示器包括位于所述指示器上的指示器部件，当所述锁定机构在其锁定位置和解锁位置之间运动时，所述指示器部件随所述锁定机构一起运动，
其中所述外壳包括指示器孔以便于所述指示器的视觉检查。
2.根据权利要求1所述的注射装置，其中当所述锁定机构处于其锁定位置时，所述指示器部件的至少一部分或全部能够通过所述指示器孔看见。
3.根据权利要求2所述的注射装置，其中当所述锁定机构处于其锁定位置时，所述指示器孔被所述指示器部件的至少一部分完全覆盖，并且当所述锁定机构不处于其锁定位置时，所述指示器孔的至少一部分不被所述指示器部件覆盖。
4.根据权利要求1所述的注射装置，其中当所述锁定机构处于其解锁位置时，所述指示器部件的至少一部分或全部能够通过所述指示器孔看见。
5.根据权利要求2所述的注射装置，其中当所述锁定机构处于其解锁位置时，所述指示器孔被所述指示器部件的至少一部分完全覆盖，并且当所述锁定机构不处于其解锁位置时，所述指示器孔的至少一部分不被所述指示器部件覆盖。
6.根据权利要求1-5中任一项所述的注射装置，其中所述锁定机构包括接触部分，所述接触部分适于在所述锁定机构处于其锁定位置时接触所述致动器的接合表面。
7.根据权利要求6所述的注射装置，其中所述接触部分适于在所述锁定机构处于其解锁位置时不接触所述致动器的接合表面。
8.根据权利要求7所述的注射装置，其中所述锁定机构能够在其锁定位置和其解锁位置之间运动，使得所述接触部分从其接触所述致动器的所述接合表面的位置运动到其不再接触所述致动器的所述接合表面的位置。
9.根据权利要求1所述注射装置，其中所述致动器在防止所述注射序列开始的第一位置和发生所述注射序列开始的第二位置之间运动。
10.根据权利要求9所述的注射装置，还包括驱动机构，其中所述致动器包括锁定表面，当所述致动器处于其第一位置时，所述锁定表面抑制所述驱动机构，并且当所述驱动机构处于其第二位置时，所述锁定表面不抑制所述驱动机构。
11.根据权利要求10所述的注射装置，还包括注射器，所述注射器能够在所述注射序列开始时由所述驱动机构从所述注射器被完全容纳在所述注射装置主体内的位置运动到所述注射器的针头经由注射开口从所述注射装置的外壳延伸的位置，其中所述驱动机构适于在所述注射器处于其延伸位置时经由所述针头排出所述注射器的内容物。
12.根据权利要求11所述的注射装置，其中当滑动部件处于其解锁位置时，所述滑动部件从所述外壳中的滑动部件开口突出。
13.根据权利要求12所述的注射装置，其中所述滑动部件开口是所述注射开口。
14.根据权利要求12或13所述的注射装置，其中所述滑动部件是滑动套筒。
15.根据权利要求1-5中任一项所述的注射装置，其中所述致动器围绕枢轴在其第一位置和第二位置之间旋转。
16.一种根据权利要求1-5中任一项所述的注射装置，
所述注射装置包含选自由以下项组成的组的物质：戈利木单抗、激素、抗毒素、用于控制疼痛的物质、用于控制血栓的物质、用于控制或消除感染的物质、肽、蛋白质、人胰岛素或人胰岛素类似物或衍生物、多糖、DNA、RNA、酶、抗体、寡核苷酸、抗过敏药、抗组胺药、抗炎药、皮质类固醇、改善病情抗风湿药、促红细胞生成素、或疫苗，
以用于治疗或预防类风湿性关节炎、牛皮癣关节炎、强直性脊柱炎、溃疡性结肠炎、激素缺乏症、中毒、疼痛、血栓、感染、糖尿病、糖尿病性视网膜病、急性冠脉综合征、心绞痛、心肌梗死、动脉粥样硬化、恶性肿瘤、黄斑变性、过敏症、花粉病、炎症、贫血或脊髓发育不良、或用于表达保护性免疫。
17.一种选自由以下项组成的组的物质：戈利木单抗、激素、抗毒素、用于控制疼痛的物质、用于控制血栓的物质、用于控制或消除感染的物质、肽、蛋白质、人胰岛素或人胰岛素类似物或衍生物、多糖、DNA、RNA、酶、抗体、寡核苷酸、抗过敏药、抗组胺药、抗炎药、皮质类固醇、改善病情抗风湿药、促红细胞生成素、或疫苗，
所述物质通过使用根据权利要求1至15中任一项所述的注射装置将所述物质递送至人类受治疗者，
以用于治疗或预防类风湿性关节炎、牛皮癣关节炎、强直性脊柱炎、溃疡性结肠炎、激素缺乏症、中毒、疼痛、血栓、感染、糖尿病、糖尿病性视网膜病、急性冠脉综合征、心绞痛、心肌梗死、动脉粥样硬化、恶性肿瘤、黄斑变性、过敏症、花粉病、炎症、贫血或脊髓发育不良、或用于表达保护性免疫。
18.一种注射装置，所述注射装置用于通过使用所述注射装置将物质递送至人类受治疗者来治疗或预防类风湿性关节炎、牛皮癣关节炎、强直性脊柱炎、溃疡性结肠炎、激素缺乏症、中毒、疼痛、血栓、感染、糖尿病、糖尿病性视网膜病、急性冠脉综合征、心绞痛、心肌梗死、动脉粥样硬化、恶性肿瘤、黄斑变性、过敏症、花粉病、炎症、贫血或脊髓发育不良、或用于表达保护性免疫，
所述物质选自由以下项组成的组：戈利木单抗、激素、抗毒素、用于控制疼痛的物质、用于控制血栓的物质、用于控制或消除感染的物质、肽、蛋白质、人胰岛素或人胰岛素类似物或衍生物、多糖、DNA、RNA、酶、抗体、寡核苷酸、抗过敏药、抗组胺药、抗炎药、皮质类固醇、改善病情抗风湿药、促红细胞生成素、或疫苗，
其中所述注射装置是根据权利要求1至15中任一项所述的注射装置。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1310402.1 | 2013-06-11 | ||
| GB1310402.1A GB2517896B (en) | 2013-06-11 | 2013-06-11 | Injection device |
| PCT/EP2014/062167 WO2014198798A2 (en) | 2013-06-11 | 2014-06-11 | Injection device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105358194A CN105358194A (zh) | 2016-02-24 |
| CN105358194B true CN105358194B (zh) | 2019-03-08 |
Family
ID=48876104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480033329.6A Active CN105358194B (zh) | 2013-06-11 | 2014-06-11 | 注射装置 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US11123492B2 (zh) |
| EP (1) | EP3007749B1 (zh) |
| JP (1) | JP5981057B2 (zh) |
| KR (1) | KR20160014767A (zh) |
| CN (1) | CN105358194B (zh) |
| AU (1) | AU2014280155B2 (zh) |
| BR (1) | BR112015030850B1 (zh) |
| CA (1) | CA2914852C (zh) |
| EA (1) | EA034009B1 (zh) |
| ES (1) | ES2949338T3 (zh) |
| GB (1) | GB2517896B (zh) |
| HK (1) | HK1207832A1 (zh) |
| IL (1) | IL242852A (zh) |
| MX (1) | MX2015017067A (zh) |
| NZ (1) | NZ715358A (zh) |
| SG (1) | SG11201510169QA (zh) |
| UA (1) | UA118193C2 (zh) |
| WO (1) | WO2014198798A2 (zh) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201731543A (zh) | 2015-12-10 | 2017-09-16 | 賽諾菲阿凡提斯德意志有限公司 | 可移除地附接於藥物輸送裝置之感測裝置 |
| KR20190022536A (ko) * | 2016-06-24 | 2019-03-06 | 아벤트, 인크. | 볼루스 재충전 표시기 |
| US11351304B2 (en) | 2016-08-30 | 2022-06-07 | Sanofi-Aventis Deutschland Gmbh | Injection device |
| DK3519018T3 (da) | 2016-09-27 | 2021-06-14 | Sanofi Aventis Deutschland | Medikamentadministrationsanordning |
| USD944225S1 (en) * | 2020-07-24 | 2022-02-22 | Sterilance Medical (Suzhou) Inc. | Lancing device |
| USD968591S1 (en) * | 2020-12-14 | 2022-11-01 | Expressions Design Studio, LLC | Safety needle |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1893992A (zh) * | 2003-12-18 | 2007-01-10 | 诺沃挪第克公司 | 具有皮肤拉紧装置的喷嘴设备 |
| CN101014379A (zh) * | 2004-05-28 | 2007-08-08 | 西拉格国际有限公司 | 注射装置 |
| CN101005868B (zh) * | 2004-05-28 | 2010-11-17 | 西拉格国际有限公司 | 注射装置 |
Family Cites Families (627)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE229932C (zh) | ||||
| DE356704C (de) | 1918-03-15 | 1922-07-27 | Edmondo Luswergh Dr | Spritze |
| DE387465C (de) | 1923-03-21 | 1924-01-03 | Agostino G Rossi Dr | Kolbenspritze |
| US1845036A (en) | 1930-03-12 | 1932-02-16 | Herbert H Busher | Hypodermic syringe |
| GB412054A (en) | 1932-08-04 | 1934-06-21 | Loewe Opta Gmbh | Improvements in wireless receivers |
| US2019382A (en) | 1935-02-19 | 1935-10-29 | Art Metal Works Inc | Torch |
| US2147616A (en) | 1937-07-09 | 1939-02-14 | Elmer J Chaput | Dental and medical hypodermic syringe |
| US2295849A (en) | 1940-10-25 | 1942-09-15 | Gustave L Kayden | Attachment for hypodermic syringes |
| US2531267A (en) | 1947-10-16 | 1950-11-21 | Harnisch Fritz | Hypodermic syringe operating device |
| DE902776C (de) | 1949-08-17 | 1954-01-28 | August Rooseboom | Selbsttaetiger Injektionsapparat mit Ampulle |
| FR1014881A (fr) | 1950-03-21 | 1952-08-25 | Appareil automatique pour injections parentérales | |
| US2764977A (en) | 1951-05-24 | 1956-10-02 | Becton Dickinson Co | Hypodermic injection mechanism |
| US2854975A (en) | 1952-08-07 | 1958-10-07 | Miljam Instr Corp | Hypodermic syringe |
| US2845065A (en) | 1954-02-05 | 1958-07-29 | Gabriel Daniel | Deception element for hypodermic syringes |
| FR1169935A (fr) | 1957-03-22 | 1959-01-07 | S E D A T Soc D Etudes Et D Ap | Perfectionnements apportés aux ampoules auto-injectables |
| US2828742A (en) | 1957-05-02 | 1958-04-01 | American Home Prod | Cartridge-needle unit |
| GB909898A (en) | 1958-04-17 | 1962-11-07 | Donald Travers Lewis | Improvements in or relating to a device for automatically effecting injections with a hypodermic syringe |
| US3076455A (en) | 1958-12-19 | 1963-02-05 | Robert K Mcconnaughey | Holder for hypodermic syringe cartridges |
| GB964585A (zh) | 1960-03-23 | |||
| US3329146A (en) | 1963-10-02 | 1967-07-04 | Baxter Laboratories Inc | Needle container |
| US3320955A (en) | 1963-10-09 | 1967-05-23 | Sarnoff Stanley Jay | Automatic injection hypodermic syringe |
| FR1538565A (fr) | 1967-07-26 | 1968-09-06 | Seringue hypodermique automatique | |
| US3543603A (en) | 1968-01-10 | 1970-12-01 | Rex Chainbelt Inc | Automatic quick release mechanism |
| NO124977B (zh) | 1968-08-09 | 1972-07-03 | Philips Nv | |
| FR2040830A5 (zh) | 1969-04-15 | 1971-01-22 | Ben Moura Pierre | |
| BE755224A (fr) | 1969-08-25 | 1971-02-24 | Philips Nv | Seringue d'injection |
| DE6944378U (de) | 1969-11-14 | 1970-04-16 | Georg A Henke Gmbh Fa | Selbsttaetiges injektionsgeraet |
| US3674033A (en) | 1970-08-13 | 1972-07-04 | John Powers | Drainage system for body cavities |
| US3702608A (en) | 1970-12-15 | 1972-11-14 | Robert C Tibbs | Painless injection device with powered plunger |
| BE795162A (fr) | 1972-02-10 | 1973-08-08 | Philips Nv | Injektie-inrichting |
| JPS4921036A (zh) | 1972-06-16 | 1974-02-25 | ||
| US3797488A (en) | 1972-07-10 | 1974-03-19 | Ampoules Inc | Ampoule applicator with one-way clutch |
| JPS4977487A (zh) | 1972-11-29 | 1974-07-25 | ||
| US3880163A (en) | 1973-10-26 | 1975-04-29 | Jack H Ritterskamp | Medicinal syringe actuating device |
| NL172403C (nl) | 1974-04-08 | 1983-09-01 | Duphar Int Res | Injectiespuit met een patroon en een patroonhouder, waarbij de patroonhouder voorzien is van vergrendelingsmiddelen voor de patroon, alsmede patroonhouder voor een injectiespuit. |
| GB1514725A (en) | 1975-05-23 | 1978-06-21 | Everett Med Prod Ltd | Hyperdermic needle assembly |
| GB1583157A (en) | 1976-05-07 | 1981-01-21 | Kenova Ab | Syringes |
| US4165739A (en) | 1976-09-02 | 1979-08-28 | Doherty Norman R | Inoculator |
| US4180070A (en) | 1977-08-29 | 1979-12-25 | Abbott Laboratories | Disposable double vial syringe |
| US4222380A (en) | 1977-12-02 | 1980-09-16 | Olympus Optical Co., Ltd. | Celiac injector |
| JPS5487694A (en) | 1977-12-23 | 1979-07-12 | Kankiyou Kagaku Kenkiyuushiyo | Granular active carbon and its manufacture |
| DE2812729A1 (de) | 1978-03-23 | 1979-09-27 | Michael Becker | Injektionsvorrichtung zur intramuskulaeren einspritzung, vornehmlich von insulin |
| US4185628A (en) | 1978-05-31 | 1980-01-29 | Kopfer Rudolph J | Compartmental syringe |
| US4194505A (en) | 1978-09-15 | 1980-03-25 | Vac-O-Cast, Inc. | Containerized hypodermic module |
| DE2929425A1 (de) | 1979-07-20 | 1981-02-12 | Lothar Kling | Vorrichtung fuer injektionsspritzen zur intramuskulaeren und subentanen injektion |
| US4237882A (en) | 1979-09-27 | 1980-12-09 | Sherwood Medical Industries Inc. | Needle sheath |
| DE8006721U1 (de) | 1980-03-12 | 1981-09-03 | Becker, Michael, 5020 Frechen | Injektionsvorrichtung zur intramuskulaeren einspritzung eines medikamentes, insbesondere von insulin |
| US4299238A (en) | 1980-06-24 | 1981-11-10 | Baidwan Balinderjeet S | Vented piston and push-rod subassembly for use in a syringe barrel |
| GB2080689B (en) | 1980-07-29 | 1984-10-31 | Dent Hugh Robert | Sterilising fitments for injection devices |
| FR2506161A1 (fr) | 1981-05-20 | 1982-11-26 | Alsetex Armement | Seringue auto-injectante |
| US4403989A (en) | 1981-09-14 | 1983-09-13 | Syntex (U.S.A.) Inc. | Injection device |
| US4407283A (en) | 1981-10-19 | 1983-10-04 | Dale C. Grier | Self-injecting syringe |
| US4394863A (en) | 1981-10-23 | 1983-07-26 | Survival Technology, Inc. | Automatic injector with cartridge having separate sequentially injectable medicaments |
| US4378015A (en) | 1981-12-21 | 1983-03-29 | Wardlaw Stephen C | Automatic injecting syringe |
| US4425120A (en) | 1982-04-15 | 1984-01-10 | Sampson Norma A | Shielded hypodermic syringe |
| US4430080A (en) | 1982-06-09 | 1984-02-07 | Becton, Dickinson And Company | Syringe assembly with snap-fit components |
| US4430082A (en) | 1982-06-25 | 1984-02-07 | Hoffmann-La Roche Inc. | Hypodermic syringe assembly |
| US4500310A (en) | 1982-12-20 | 1985-02-19 | Becton, Dickinson And Company | Variable sealing pressure plunger rod assembly |
| US4676530A (en) | 1983-04-07 | 1987-06-30 | Warner-Lambert Company | Coupling assembly for use in fluid flow systems |
| US4521237A (en) | 1983-05-23 | 1985-06-04 | Kahle Engineering Co. | Glass dose syringe |
| US4561856A (en) | 1983-08-18 | 1985-12-31 | Cochran Ulrich D | Infusion pump |
| DE3342407A1 (de) | 1983-11-24 | 1985-06-05 | Erwin 6950 Mosbach Maurer | Injektionsgeraet |
| AU573369B2 (en) | 1984-07-31 | 1988-06-02 | N.J. Phillips Pty. Limited | A rumen injector |
| NZ212899A (en) | 1984-07-31 | 1987-10-30 | Phillips Pty Ltd N J | Piston operated adjustable volume dose injector for animals |
| DD234613A1 (de) | 1985-02-14 | 1986-04-09 | Karl Marx Stadt Tech Hochschul | Vorrichtung mit tagesmedikamentdepot zur schmerzarmen injektion |
| US4627835A (en) | 1985-03-11 | 1986-12-09 | Strato Medical Corporation | Tubing assembly for infusion device |
| US4636201A (en) | 1985-11-01 | 1987-01-13 | American Hospital Supply Corporation | Hypodermic syringe having a protective sheath cover |
| US4636198A (en) | 1985-11-18 | 1987-01-13 | Mallinckrodt, Inc. | Power syringe with volume reducing adapter |
| US4695274A (en) | 1986-01-31 | 1987-09-22 | Fox Richard L | Protected hypodermic needle |
| US4639250A (en) | 1986-02-20 | 1987-01-27 | Becton, Dickinson And Company | Syringe barrel and hypodermic needle assembly |
| US4735311A (en) | 1986-04-09 | 1988-04-05 | The West Company | Needle shield assembly |
| US4744786A (en) | 1986-06-17 | 1988-05-17 | Cordis Corporation | Infusion pump |
| FR2600258A1 (fr) | 1986-06-18 | 1987-12-24 | Hazon Bernard | Dispositif pousse-seringue pour injections parenterales automatiques a asservissement et programmation |
| DE3645245C2 (de) | 1986-11-14 | 1994-01-27 | Haselmeier Wilhelm Fa | Injektionsgerät |
| CA1285441C (en) | 1987-03-17 | 1991-07-02 | Roy D. Mcnaughton | Mcnaughton syringe shield type b |
| DE3715258C2 (de) | 1987-05-08 | 1996-10-31 | Haselmeier Wilhelm Fa | Injektionsgerät |
| FR2629706B1 (fr) | 1988-04-11 | 1992-05-22 | Accaries Claude | Appareil d'injection de liquide, notamment a usage de soins dentaires |
| WO1988010129A1 (en) | 1987-06-25 | 1988-12-29 | Nova Medical Pty. Limited | Slow delivery injection device |
| US5364369A (en) | 1987-07-08 | 1994-11-15 | Reynolds David L | Syringe |
| US4874384A (en) | 1987-07-13 | 1989-10-17 | International Medical Innovators, Inc. | Needle safety guard |
| US4787891A (en) | 1987-07-13 | 1988-11-29 | Paul Levin | Syringe holder and applicator |
| AU3071689A (en) | 1988-03-01 | 1989-09-07 | Ryan Medical, Inc. | Safety needled medical devices capable of one-handed manipulation |
| JPH0534669Y2 (zh) | 1988-03-16 | 1993-09-02 | ||
| GB8809115D0 (en) | 1988-04-18 | 1988-05-18 | Turner R C | Syringes |
| US5156599A (en) | 1988-06-28 | 1992-10-20 | Sherwood Medical Company | Syringe and sliding locking needle shield |
| US5026349A (en) | 1988-10-05 | 1991-06-25 | Autoject Systems Inc. | Liquid medicament injector system |
| FR2638359A1 (fr) | 1988-11-03 | 1990-05-04 | Tino Dalto | Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau |
| US5263933A (en) | 1988-12-14 | 1993-11-23 | Patco Ventures Ltd. | Safety syringe needle device with interchangeable and retractable needle platform |
| JPH02185261A (ja) | 1988-12-20 | 1990-07-19 | Candera Estourci Miracle | 注射器 |
| US4988339A (en) | 1988-12-30 | 1991-01-29 | Vadher Dinesh L | Retractable needle/syringe devices for blood collection, catheterization, and medicinal injection procedures |
| US4929232A (en) | 1989-03-30 | 1990-05-29 | Becton, Dickinson And Company | Syringe having tamper evidence features |
| JPH02299660A (ja) | 1989-05-15 | 1990-12-11 | Yokoshima Rika Sangyo Kk | 容器兼用注射器への薬液充填方法 |
| US4969870A (en) | 1989-06-07 | 1990-11-13 | The Regents Of The University Of California | Method and apparatus for intraosseous infusions |
| US6096005A (en) | 1989-07-11 | 2000-08-01 | Mdc Investment Holdings, Inc. | Retractable needle medical devices |
| US4994034A (en) | 1989-07-11 | 1991-02-19 | Botich Michael J | Retractable needle hypodermic syringe system |
| DE3929777A1 (de) | 1989-09-07 | 1991-03-14 | Dieter Dr Lucas | Injektionsspritze |
| JPH03129156A (ja) | 1989-10-14 | 1991-06-03 | Shigeru Hayashi | 摩擦車駆動機構 |
| US5112119A (en) | 1989-10-27 | 1992-05-12 | International Business Machines Corp. | Support structure for devices in a computer apparatus |
| US5312335A (en) | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
| GB8926825D0 (en) | 1989-11-28 | 1990-01-17 | Glaxo Group Ltd | Device |
| CN2059579U (zh) | 1989-12-22 | 1990-07-25 | 国营建安机械厂 | 兽用静脉进针器 |
| CA2071906C (en) | 1990-02-12 | 1999-12-28 | Diane Lynn Furio | Odor controlling compositions and articles |
| US5057079A (en) | 1990-04-03 | 1991-10-15 | Roland Tiemann | Sheathing device for after use protection from a syringe needle |
| US5624400A (en) | 1990-05-09 | 1997-04-29 | Safety Syringes, Inc. | Disposable self-shielding aspirating syringe |
| SG42825A1 (en) | 1990-07-04 | 1997-10-17 | Maxwell Edmund Whisson | Improved parenteral device |
| FR2665079A1 (fr) | 1990-07-27 | 1992-01-31 | Conception Fabr Innovations Me | Seringue a aiguille jetable. |
| US5073170A (en) | 1990-08-09 | 1991-12-17 | Hollister Incorporated | Drainage tube retention device |
| GB9100819D0 (en) | 1991-01-15 | 1991-02-27 | Medimech Int Ltd | Subcutaneous injector |
| US5098400A (en) | 1991-02-14 | 1992-03-24 | Sherwood Medical Company | Needle shield |
| US5188613A (en) | 1991-04-03 | 1993-02-23 | Shaw Thomas J | Nonreusable syringe with safety indicator |
| US5868711A (en) | 1991-04-29 | 1999-02-09 | Board Of Regents, The University Of Texas System | Implantable intraosseous device for rapid vascular access |
| US5451210A (en) | 1991-04-29 | 1995-09-19 | Lifequest Medical, Inc. | System and method for rapid vascular drug delivery |
| US5176643A (en) | 1991-04-29 | 1993-01-05 | George C. Kramer | System and method for rapid vascular drug delivery |
| US5405362A (en) | 1991-04-29 | 1995-04-11 | The Board Of Regents For The University Of Texas System | Interactive external defibrillation and drug injection system |
| US5271744A (en) | 1991-04-29 | 1993-12-21 | George C. Kramer | System and method for rapid vascular drug delivery |
| US5147325A (en) | 1991-05-03 | 1992-09-15 | Sherwood Medical Company | Rigid needle shield |
| GB9111600D0 (en) | 1991-05-30 | 1991-07-24 | Owen Mumford Ltd | Improvements relating to injection devices |
| EP0518416A1 (en) | 1991-06-13 | 1992-12-16 | Duphar International Research B.V | Injection device |
| GB9115765D0 (en) | 1991-07-22 | 1991-09-04 | Britt Adrian J | Bacterial enzyme for cocaine detection |
| EP0525525B1 (de) | 1991-07-24 | 1995-05-03 | Medico Development Investment Company | Injektor |
| ATE179876T1 (de) | 1991-11-12 | 1999-05-15 | Urs A Ramel | Lanzetteneinrichtung |
| US5242400A (en) | 1991-12-06 | 1993-09-07 | The Medtech Group, Inc. | Disposable pre-filled syringe with retractable needle |
| GB9200219D0 (en) | 1992-01-07 | 1992-02-26 | Medimech Int Ltd | Automatic injectors |
| US5242416A (en) | 1992-01-09 | 1993-09-07 | Hutson Clifford L | Shield assembly for needle syringes |
| EP0562671B1 (en) | 1992-03-27 | 1996-05-29 | Duphar International Research B.V | Automatic injector |
| ZA932947B (en) | 1992-04-28 | 1993-10-27 | Schering Plough Healthcare | Applicator for semisolid medications |
| US6290683B1 (en) | 1992-04-29 | 2001-09-18 | Mali-Tech Ltd. | Skin piercing needle assembly |
| MX9302834A (es) | 1992-05-15 | 1993-11-01 | Safe T Ltd | Aplicador de aguja hueca. |
| US5250026A (en) | 1992-05-27 | 1993-10-05 | Destron/Idi, Inc. | Adjustable precision transponder injector |
| US5267962A (en) | 1992-06-10 | 1993-12-07 | Jenson Robert W | Disposable hypodermic syringe with needle safe feature |
| EP0585626A1 (de) | 1992-08-14 | 1994-03-09 | Hoechst Aktiengesellschaft | Kaschierte Mineralfasermatte |
| AU5016893A (en) | 1992-08-17 | 1994-03-15 | Edward F. Allard | Method and apparatus for a retracting needle |
| US5267963A (en) | 1992-08-21 | 1993-12-07 | Nicholas Bachynsky | Medication injection device |
| EP0658090B1 (en) | 1992-09-01 | 1998-11-04 | Edwin L. Adair | Sterilizable endoscope with separable disposable tube assembly |
| US5190526A (en) | 1992-09-18 | 1993-03-02 | Murray Kenneth W | Hypodermic safety syringe with retracting needle system |
| US5569189A (en) | 1992-09-28 | 1996-10-29 | Equidyne Systems, Inc. | hypodermic jet injector |
| AU5293393A (en) | 1992-09-28 | 1994-04-26 | Equidyne Systems, Incorporated | Hypodermic jet injector |
| US5681291A (en) | 1992-11-19 | 1997-10-28 | Tebro S.A. | Disposable auto-injector for prefilled syringes |
| US5320609A (en) | 1992-12-07 | 1994-06-14 | Habley Medical Technology Corporation | Automatic pharmaceutical dispensing syringe |
| IT1256577B (it) | 1992-12-11 | 1995-12-11 | Ermanno Greco | Dispositivo predisposto per la somministrazione automatica di un farmaco per via intradermica. |
| US5370621A (en) | 1992-12-14 | 1994-12-06 | Mallinckrodt Medical, Inc. | Insert device for facilitating limited aspiration of a delivery apparatus |
| DK0625917T3 (da) | 1992-12-15 | 1998-09-28 | Sanofi Sa | Indretning til præparation af en opløsning, en suspension eller en emulsion af en medicinsk substans |
| US5250037A (en) | 1992-12-18 | 1993-10-05 | Becton, Dickinson And Company | Syringe having needle isolation features |
| DE69427226T2 (de) | 1993-03-24 | 2001-08-30 | Owen Mumford Ltd., Woodstock | Vorrichtung zur injektion |
| US5540666A (en) | 1993-03-31 | 1996-07-30 | Immuno Aktiengesellschaft | Cannula shield and injection syringe system |
| US5330081A (en) | 1993-04-08 | 1994-07-19 | Impact Products, Inc. | Measuring dosage dispenser |
| JP3296025B2 (ja) | 1993-05-21 | 2002-06-24 | ニプロ株式会社 | 薬液充填式注射器 |
| US5368577A (en) | 1993-05-24 | 1994-11-29 | Biocon International Corporation | Needle stick prevention device |
| WO1995031235A1 (en) | 1994-05-16 | 1995-11-23 | Washington Biotech Corporation | Modular automatic or manual emergency medicine injection system |
| US5358489A (en) | 1993-05-27 | 1994-10-25 | Washington Biotech Corporation | Reloadable automatic or manual emergency injection system |
| US5540664A (en) | 1993-05-27 | 1996-07-30 | Washington Biotech Corporation | Reloadable automatic or manual emergency injection system |
| DE69426390T2 (de) * | 1993-07-31 | 2001-04-12 | Weston Medical Ltd., Stradbroke Eye | Nadelloser injektor |
| US5425715A (en) | 1993-08-05 | 1995-06-20 | Survival Technology, Inc. | Reloadable injector |
| US5312364A (en) | 1993-08-06 | 1994-05-17 | Pyng | Intraosseous infusion device |
| JP3199524B2 (ja) | 1993-08-06 | 2001-08-20 | 日本メジフィジックス株式会社 | ルアーニードルユニット及び注射器 |
| FR2717086A1 (fr) | 1994-03-11 | 1995-09-15 | Debiotech | Dispositif de seringue pour le mélange de deux composés. |
| BR9407390A (pt) | 1993-09-07 | 1996-11-05 | Debiotech Sa | Dispositivo de seringa para mistura de dois compostos |
| US5385551A (en) | 1993-09-22 | 1995-01-31 | Shaw; Thomas J. | Nonreusable medical device with front retraction |
| JPH07120326A (ja) | 1993-10-22 | 1995-05-12 | Komatsu Ltd | 波長検出装置 |
| US5372586A (en) | 1993-10-20 | 1994-12-13 | Habley Medical Technology Corp. | Telescoping pharmaceutical storage and mixing syringe |
| JPH07116224A (ja) | 1993-10-28 | 1995-05-09 | Arute:Kk | 注射器 |
| CA2135706C (en) | 1993-11-15 | 1999-06-15 | Walter E. Cover | Retractable-needle cannula insertion set with refinements to better control leakage, retraction speed, and reuse |
| US5330430A (en) | 1993-12-06 | 1994-07-19 | Sullivan Robert J | Retractable syringe applicator |
| US5356395A (en) | 1993-12-14 | 1994-10-18 | Chen Shih Shuan | Safety syringe shield |
| FR2715071B1 (fr) | 1994-01-17 | 1996-03-01 | Aguettant Lab | Injecteur automatique de médicament. |
| JPH07213610A (ja) | 1994-01-28 | 1995-08-15 | Shirota Denki Rozai Kk | 歯科用の電動注射器 |
| US5478316A (en) | 1994-02-02 | 1995-12-26 | Becton, Dickinson And Company | Automatic self-injection device |
| US5514097A (en) | 1994-02-14 | 1996-05-07 | Genentech, Inc. | Self administered injection pen apparatus and method |
| WO1995024176A1 (en) | 1994-03-07 | 1995-09-14 | Bioject, Inc. | Ampule filling device |
| FR2718357B1 (fr) | 1994-04-06 | 1997-10-03 | Defarges Alain Moreau | Perfectionnements apportés à un dispositif d'injection par jet sans aiguille. |
| GB9408500D0 (en) | 1994-04-28 | 1994-06-22 | Pa Consulting Services | Improvements in or relating to injection devices |
| US5411488A (en) | 1994-05-06 | 1995-05-02 | Sterling Winthrop Inc. | Pre-filled syringe and pre-filled cartridge having an improved plunger and plunger rod for reducing syringing force |
| US5609584A (en) | 1994-05-18 | 1997-03-11 | Gettig Technologies, Inc. | Adaptor system for use with a syringe |
| EP0762904B1 (de) | 1994-05-30 | 2002-10-02 | B D Medico S.à.r.l. | Injektionsgerät |
| GB9412301D0 (en) | 1994-06-17 | 1994-08-10 | Safe T Ltd | Hollow-needle drugs etc applicators |
| WO1996000053A1 (en) | 1994-06-24 | 1996-01-04 | Icu Medical, Inc. | Fluid transfer device and method of use |
| DE69507088T2 (de) | 1994-07-27 | 1999-05-27 | Meridian Medical Technologies, Inc., Columbia, Md. | Automatische Spritze |
| DE4428467A1 (de) | 1994-08-11 | 1996-02-15 | Dietmar Dr Med Enk | Spritze mit Kolbendruckdämpfung und Verfahren zur langsamen und gleichmäßigen Injektion einer Flüssigkeit mittels dieser Spritze |
| DE69534233T2 (de) | 1994-09-16 | 2005-10-27 | Ethicon Endo-Surgery, Inc., Cincinnati | Vorrichtungen zum bestimmen und markieren von gewebe |
| AUPM922394A0 (en) | 1994-11-03 | 1994-11-24 | Astra Pharmaceuticals Pty Ltd | Plastic syringe with overcap |
| US5637094A (en) | 1994-11-04 | 1997-06-10 | Pos-T-Vac, Inc. | Multiple dosage syringe |
| US5599302A (en) | 1995-01-09 | 1997-02-04 | Medi-Ject Corporation | Medical injection system and method, gas spring thereof and launching device using gas spring |
| US5647845A (en) | 1995-02-01 | 1997-07-15 | Habley Medical Technology Corporation | Generic intravenous infusion system |
| US5607395A (en) | 1995-02-02 | 1997-03-04 | Ragsdale; Ronald | Device for remote injection of animals |
| GB9504878D0 (en) | 1995-03-10 | 1995-04-26 | Weston Medical Ltd | Viscously coupled actuator |
| GB9506087D0 (en) | 1995-03-24 | 1995-05-10 | Owen Mumford Ltd | Improvements relating to medical injection devices |
| US5779668A (en) | 1995-03-29 | 1998-07-14 | Abbott Laboratories | Syringe barrel for lyophilization, reconstitution and administration |
| FR2733155B1 (fr) | 1995-04-18 | 1997-09-19 | Tebro | Auto-injecteur rechargeable |
| FR2733687B1 (fr) | 1995-05-04 | 1997-10-03 | Brunel Marc | Procede de fabrication d'un dispositif d'injection du type pre-rempli renfermant une dose de liquide a injecter, et dispositif d'injection realise |
| FR2736553B1 (fr) | 1995-07-12 | 1998-01-09 | Soc Et Et D Applic Tech Sedat | Seringue d'injection, notamment de produits medicaux liquides, a protecteur d'aiguille mobile |
| DE29513214U1 (de) | 1995-08-21 | 1997-01-02 | Adamaszek, Franz-Heinz, 70193 Stuttgart | Dosier- und automatisches Injektionssystem |
| US5520653A (en) | 1995-09-01 | 1996-05-28 | Medrad, Inc. | Syringe adapter for front-loading medical injector |
| US5674204A (en) | 1995-09-19 | 1997-10-07 | Becton Dickinson And Company | Medication delivery pen cap actuated dose delivery clutch |
| FR2739564B3 (fr) | 1995-10-06 | 1998-04-10 | Calomili Gerard | Seringue de securite a usage unique, dont la canule d'aiguille se retracte automatiquement et entierement apres le premier usage |
| US5658259A (en) | 1995-10-19 | 1997-08-19 | Meridian Medical Technologies, Inc. | Dental cartridge assembly auto-injector with protective needle cover |
| US5807334A (en) | 1995-10-20 | 1998-09-15 | Hodosh; Milton | Fluid dispensing apparatus |
| US6159161A (en) | 1995-10-20 | 2000-12-12 | Hodosh; Milton | Microprocessor-controlled fluid dispensing apparatus |
| US5567160A (en) | 1995-10-26 | 1996-10-22 | Survival Technology, Inc. | Autoinjector training device |
| US5997513A (en) | 1995-11-22 | 1999-12-07 | Smith; Jerry A. | Syringe cover cooperating with needle cover |
| FR2741810B1 (fr) | 1995-11-30 | 1998-02-20 | Soc Et Et D Applic Tech Sedat | Seringue pour l'injection d'un melange extemporane |
| US5899879A (en) | 1995-12-19 | 1999-05-04 | Genesis Medical Technologies, Inc. | Spring-actuated needleless injector |
| US5634906A (en) | 1995-12-27 | 1997-06-03 | Habley Medical Technology Corporation | Needle hiding shield for a dose metering syringe |
| US5609577A (en) | 1996-01-29 | 1997-03-11 | Haber; Terry M. | Automatically locking hypodermic needle hiding shield for a dose metering syringe |
| DE19603707A1 (de) | 1996-02-02 | 1997-08-07 | Carnaudmetalbox Sa | Dosiervorrichtung für komprimierbare Behältnisse |
| JPH09225029A (ja) | 1996-02-26 | 1997-09-02 | Material Eng Tech Lab Inc | 注射器及びその製造方法 |
| US5865795A (en) | 1996-02-29 | 1999-02-02 | Medi-Ject Corporation | Safety mechanism for injection devices |
| GB9606829D0 (en) | 1996-03-30 | 1996-06-05 | Jeffrey Peter | Supplying materials etc |
| IT1284642B1 (it) | 1996-05-02 | 1998-05-21 | Ermanno Greco | Perfezionamenti alle siringhe automatiche per iniezione |
| GB9612724D0 (en) | 1996-06-18 | 1996-08-21 | Owen Mumford Ltd | Improvements relating to injection devices |
| ATE249259T1 (de) | 1996-07-05 | 2003-09-15 | Novo Nordisk As | Vorrichtung zur automatischen einführung einer nadel |
| US5843036A (en) | 1996-08-23 | 1998-12-01 | Becton Dickinson And Company | Non-dosing cartridge for an injection device |
| US5709662A (en) | 1996-08-23 | 1998-01-20 | Becton Dickinson France, S.A. | Cartridge for an injection device |
| WO1998011927A1 (de) | 1996-09-20 | 1998-03-26 | Disetronic Licensing Ag | Abtriebsglied für den vorschub eines stopfens einer spritzampulle und stopfen hierzu |
| US5697908A (en) | 1996-09-26 | 1997-12-16 | Becton Dickinson France, S.A. | Lockable safety shield for a prefillable syringe |
| DE69635167T2 (de) | 1996-10-09 | 2006-07-27 | HNS International Inc., Anaheim | Subkutaner druckstrahlinjektor |
| US5873861A (en) | 1996-11-12 | 1999-02-23 | Medrad, Inc. | Plunger systems |
| US6090897A (en) | 1996-12-09 | 2000-07-18 | Nippon Shokubai Co., Ltd. | Curable resin composition and its use |
| US5817058A (en) | 1996-12-23 | 1998-10-06 | Shaw; Thomas J. | Retractable catheter introducer structure |
| US6203530B1 (en) | 1997-01-28 | 2001-03-20 | Pos-T-Vac, Inc. | Auto-injection device |
| BR9700930A (pt) | 1997-02-07 | 1998-12-08 | Rhone Poulenc Rorer Gmbh | Unidade para venda que se destina a aplicação parenteral um dispositivo para a execução da aplicação parenteral bem como uma unidade de recarga destinada á unidade para venda acima mencionada |
| CN1190599A (zh) | 1997-02-12 | 1998-08-19 | 约尼-鲍伦斯·劳拉有限公司 | 胃肠外使用的成套商品,设备及成套备品 |
| US6159184A (en) | 1997-03-10 | 2000-12-12 | Safety Syringes, Inc. | Disposable self-shielding unit dose syringe guard |
| US6331172B1 (en) | 1997-04-14 | 2001-12-18 | Baxter International Inc. | Applicator for dispensing measured quantities with use of controlled suction |
| US5989229A (en) | 1997-05-28 | 1999-11-23 | Becton, Dickinson And Company | Needle cover assembly having self-contained drug applicator |
| US6454746B1 (en) | 1997-06-04 | 2002-09-24 | Eli Lilly And Company | Medication delivery apparatus |
| US5865804A (en) | 1997-07-16 | 1999-02-02 | Bachynsky; Nicholas | Rotary cam syringe |
| GB9714948D0 (en) | 1997-07-16 | 1997-09-17 | Owen Mumford Ltd | Improvements relating to injection devices |
| US5954738A (en) | 1997-07-31 | 1999-09-21 | Bayer Corporation | Blood sampling device with lancet damping system |
| GB9716065D0 (en) | 1997-07-31 | 1997-10-01 | Owen Mumford Ltd | Improvements relating to injection devices |
| US6171276B1 (en) | 1997-08-06 | 2001-01-09 | Pharmacia & Upjohn Ab | Automated delivery device and method for its operation |
| PT1003580E (pt) | 1997-08-21 | 2004-01-30 | Ares Trading Sa | Aperfeicoamento relativos a dispositivos para injeccoes |
| US6569115B1 (en) | 1997-08-28 | 2003-05-27 | Mdc Investment Holdings, Inc. | Pre-filled retractable needle injection device |
| AU9202398A (en) | 1997-09-29 | 1999-04-23 | Becton Dickinson & Company | Injection device and drug cartridge for preventing cross-use of the device and drug cartridge |
| US6090078A (en) | 1997-09-30 | 2000-07-18 | Becton, Dickinson And Company | Dampening devices and methods for needle retracting safety vascular access devices |
| US6004296A (en) | 1997-09-30 | 1999-12-21 | Becton Dickinson France, S.A. | Lockable safety shield assembly for a prefillable syringe |
| IE970782A1 (en) | 1997-10-22 | 1999-05-05 | Elan Corp | An improved automatic syringe |
| US6045534A (en) | 1997-10-27 | 2000-04-04 | Sarcos, Inc. | Disposable fluid injection module |
| US6086562A (en) | 1997-10-27 | 2000-07-11 | Sarcos, Inc. | Disposable automatic injection device |
| US6461333B1 (en) | 1997-10-30 | 2002-10-08 | Laboratoire Aquettant | Safety syringe for medical use |
| FR2770404B1 (fr) | 1997-11-05 | 2000-01-28 | Sedat | Injecteur automatique a retraction d'aiguille en fin d'injection |
| US6015438A (en) | 1997-11-14 | 2000-01-18 | Retractable Technologies Inc. | Full displacement retractable syringe |
| US5913843A (en) | 1997-11-26 | 1999-06-22 | Jentzen; S. William | Dampening device for spring movement |
| JPH11164887A (ja) | 1997-12-05 | 1999-06-22 | Nippon Zeon Co Ltd | 筒状成形体 |
| WO1999033504A1 (en) * | 1997-12-31 | 1999-07-08 | Minimed Inc. | Insertion device for an insertion set and method of using the same |
| IT1304761B1 (it) | 1998-01-20 | 2001-03-29 | Nardino Righi | Siringa monouso di sicurezza. |
| DE29801168U1 (de) | 1998-01-24 | 1999-08-12 | Medico Dev Investment Co | Injektionsgerät |
| FR2774294B1 (fr) | 1998-02-04 | 2000-04-14 | Marc Brunel | Dispositif d'injection automatique d'une dose de produit medicamenteux |
| GB9803084D0 (en) | 1998-02-14 | 1998-04-08 | Owen Mumford Ltd | Improvements relating to medical injection devices |
| CA2229522A1 (en) | 1998-04-15 | 1999-10-15 | Thomas Randall Inkpen | Needle aid |
| GB9808408D0 (en) | 1998-04-18 | 1998-06-17 | Owen Mumford Ltd | Improvements relating to injection devices |
| US6209738B1 (en) | 1998-04-20 | 2001-04-03 | Becton, Dickinson And Company | Transfer set for vials and medical containers |
| DE19819409A1 (de) | 1998-04-30 | 1999-11-11 | Schering Ag | Injektionsvorrichtung |
| WO1999056775A1 (en) | 1998-05-07 | 1999-11-11 | Akzo Nobel N.V. | Use of interleukin-18 as vaccine adjuvant |
| DE19821933C1 (de) | 1998-05-15 | 1999-11-11 | Disetronic Licensing Ag | Vorrichtung zur Verabreichung eines injizierbaren Produkts |
| DE19822031C2 (de) | 1998-05-15 | 2000-03-23 | Disetronic Licensing Ag | Autoinjektionsgerät |
| FR2778853B1 (fr) | 1998-05-19 | 2000-12-22 | Sedat | Seringue d'injection a protecteur d'aiguille charge par un ressort |
| JP2002521147A (ja) | 1998-07-27 | 2002-07-16 | メディ−ジェクト コーポレイション | 医用注射器組立体に使用する装填機構 |
| US6358236B1 (en) | 1998-08-06 | 2002-03-19 | Baxter International Inc. | Device for reconstituting medicaments for injection |
| US6428528B2 (en) | 1998-08-11 | 2002-08-06 | Antares Pharma, Inc. | Needle assisted jet injector |
| GB9817662D0 (en) | 1998-08-13 | 1998-10-07 | Crocker Peter J | Substance delivery |
| WO2000013723A2 (en) | 1998-09-04 | 2000-03-16 | Owen Mumford Limited | Improvements relating to fluid tranfer assemblies |
| FR2784033B1 (fr) | 1998-10-01 | 2000-12-22 | Marc Brunel | Dispositif d'injection a usage unique destine a etre pre-rempli |
| US6506177B2 (en) | 1998-10-14 | 2003-01-14 | Sergio Landau | Needle-less injection system |
| SE9803662D0 (sv) | 1998-10-26 | 1998-10-26 | Pharmacia & Upjohn Ab | Autoinjector |
| JP2000126293A (ja) | 1998-10-28 | 2000-05-09 | Shimadzu Corp | 針無注射器 |
| US20020173748A1 (en) | 1998-10-29 | 2002-11-21 | Mcconnell Susan | Reservoir connector |
| WO2000029049A1 (en) | 1998-11-13 | 2000-05-25 | Elan Pharma International Limited | Drug delivery systems and methods |
| US6783509B1 (en) | 1998-11-18 | 2004-08-31 | Bioject Inc. | Single-use needle-less hypodermic jet injection apparatus and method |
| US6264629B1 (en) | 1998-11-18 | 2001-07-24 | Bioject, Inc. | Single-use needle-less hypodermic jet injection apparatus and method |
| US6689093B2 (en) | 1998-11-18 | 2004-02-10 | Bioject, Inc. | Single-use needle-less hypodermic jet injection apparatus and method |
| DE29822494U1 (de) | 1998-12-17 | 2000-05-04 | Medico Development Investment Co., Ascona | Injektionsgerät |
| US6036675A (en) | 1999-02-03 | 2000-03-14 | Specialized Health Products, Inc. | Safety sterile cartride unit apparatus and methods |
| GB9903475D0 (en) | 1999-02-17 | 1999-04-07 | Owen Mumford Ltd | Improvements relating to injection devices |
| IL128709A (en) | 1999-02-24 | 2004-09-27 | Teva Medical Ltd | Fluid sampling apparatus |
| US6258062B1 (en) | 1999-02-25 | 2001-07-10 | Joseph M. Thielen | Enclosed container power supply for a needleless injector |
| FR2790948B1 (fr) | 1999-03-18 | 2001-06-22 | Sedat | Dispositif de transfert bidirectionnel d'un liquide entre un flacon et une capsule |
| AU5614199A (en) | 1999-04-14 | 2000-11-14 | Thomas Randall Inkpen | Needle injection-facilitating device |
| NO310224B1 (no) | 1999-04-22 | 2001-06-11 | Medical Needle As | Engangsspröyte med automatisk tilbaketrekkbar kanyle |
| US20040069044A1 (en) | 1999-04-29 | 2004-04-15 | Gilad Lavi | Device for measuring a volume of drug |
| SE9901736D0 (sv) | 1999-05-12 | 1999-05-12 | Pharmacia & Upjohn Ab | Injectino device and method for ITS operation |
| NZ335985A (en) | 1999-05-27 | 2001-04-27 | Simcro Tech Ltd | Measuring dispenser for a container |
| US6330960B1 (en) | 1999-06-04 | 2001-12-18 | Mcneil-Ppc, Inc. | Squeeze dispenser |
| DE60023511T2 (de) | 1999-07-15 | 2006-04-20 | Bracco International B.V. | Kolben für spritze |
| HU225877B1 (en) | 1999-07-27 | 2007-11-28 | Pharma Consult Gmbh | Device for automatically injecting injection liquids |
| US6238374B1 (en) | 1999-08-06 | 2001-05-29 | Proxima Therapeutics, Inc. | Hazardous fluid infuser |
| JP2001046498A (ja) | 1999-08-06 | 2001-02-20 | Shimadzu Corp | 針無注射器 |
| JP3514428B2 (ja) | 1999-08-24 | 2004-03-31 | 日本ベルボン精機工業株式会社 | 三 脚 |
| US6491667B1 (en) | 1999-08-31 | 2002-12-10 | Becton, Dickinson And Company | Syringe tip cap |
| US6162199A (en) | 1999-09-20 | 2000-12-19 | Geringer; Joseph Robert | Device for loading a syringe from a vial |
| US6579269B1 (en) | 1999-09-21 | 2003-06-17 | Gennady I. Kleyman | Dosage device |
| FR2799375B1 (fr) | 1999-10-07 | 2002-01-18 | Marc Brunel | Dispositif d'injection a usage unique |
| FR2799654B1 (fr) | 1999-10-13 | 2002-01-11 | Sod Conseils Rech Applic | Dispositif pour reconstituer une solution, une suspension ou une dispersion therapeutique et procede de preparation et de conditionnement dans ce dispositif |
| US6569123B2 (en) | 1999-10-14 | 2003-05-27 | Becton, Dickinson And Company | Prefillable intradermal injector |
| US6494865B1 (en) | 1999-10-14 | 2002-12-17 | Becton Dickinson And Company | Intradermal delivery device including a needle assembly |
| US6391003B1 (en) | 1999-10-25 | 2002-05-21 | Antares Pharma, Inc. | Locking mechanism for a jet injector |
| US7029457B2 (en) | 1999-11-23 | 2006-04-18 | Felton International, Inc. | Jet injector with hand piece |
| DE69919903T2 (de) | 1999-12-08 | 2005-09-15 | Union Medico | Infusionsvorrichtung |
| US6425885B1 (en) | 1999-12-20 | 2002-07-30 | Ultradent Products, Inc. | Hydraulic syringe |
| US6926696B2 (en) | 1999-12-23 | 2005-08-09 | Owais Mohammed | Hypodermic syringe needle assembly and method of making the same |
| AU3184101A (en) | 2000-01-07 | 2001-07-16 | Sanofi-Synthelabo | Device for injecting a dose of liquid, in particular medicinal liquid |
| US6190363B1 (en) | 2000-01-24 | 2001-02-20 | Bracco Diagnostics, Inc. | Self-aligning plunger rod |
| US6139534A (en) | 2000-01-24 | 2000-10-31 | Bracco Diagnostics, Inc. | Vial access adapter |
| US7799009B2 (en) | 2000-01-24 | 2010-09-21 | Bracco Diagnostics Inc. | Tabletop drug dispensing vial access adapter |
| GB0002095D0 (en) * | 2000-01-28 | 2000-03-22 | Novartis Ag | Device |
| US6595957B1 (en) | 2000-01-31 | 2003-07-22 | Ethicon, Inc. | Surgical fluid management system with a dampening chamber |
| JP2001212237A (ja) | 2000-01-31 | 2001-08-07 | Shimadzu Corp | 針無注射器 |
| WO2001060311A1 (de) | 2000-02-16 | 2001-08-23 | B D Medico S.A.R.L. | Verfahren zur rekonstitution einer injektionsflüssigkeit, und injektionsgerät zur durchführung eines solchen verfahrens |
| GB0003790D0 (en) | 2000-02-18 | 2000-04-05 | Astrazeneca Uk Ltd | Medical device |
| US20030032928A1 (en) | 2000-03-02 | 2003-02-13 | Morihiro Sudo | Prefilled syringe assembly |
| FR2805868A1 (fr) | 2000-03-02 | 2001-09-07 | Peugeot Citroen Automobiles Sa | Organe elastique, du type ressort a compression |
| US7527607B2 (en) | 2000-03-06 | 2009-05-05 | Mdc Investment Holdings, Inc. | Hypodermic syringe with retractable needle |
| US6855130B2 (en) | 2000-03-07 | 2005-02-15 | Becton, Dickinson And Company | Passive safety device for needle of IV infusion or blood collection set |
| US6832992B2 (en) | 2000-03-07 | 2004-12-21 | Becton, Dickinson And Company | Passive safety device for needle of blood collection set |
| GB0007071D0 (en) | 2000-03-24 | 2000-05-17 | Sams Bernard | One-way clutch mechanisms and injector devices |
| US6371959B1 (en) | 2000-04-05 | 2002-04-16 | Michael E. Trice | Radiolucent position locating device and drill guide |
| US6471677B2 (en) | 2000-04-06 | 2002-10-29 | Gem Plastics, Inc. | Fluid collection device with protective shield |
| US6558348B2 (en) | 2000-04-07 | 2003-05-06 | Equidyne Systems, Inc. | Low cost disposable needleless injector system for variable and fixed dose applications |
| US20040241651A1 (en) | 2000-04-07 | 2004-12-02 | Alexander Olek | Detection of single nucleotide polymorphisms (snp's) and cytosine-methylations |
| GB0008955D0 (en) | 2000-04-12 | 2000-05-31 | Owen Mumford Ltd | An injector pack |
| US6607508B2 (en) | 2000-04-27 | 2003-08-19 | Invivotech, Inc. | Vial injector device |
| US6183134B1 (en) | 2000-05-04 | 2001-02-06 | Illinois Tool Works, Inc. | High internal force resistant peel sealable zipper |
| US6613022B1 (en) | 2000-05-05 | 2003-09-02 | Safety Syringes, Inc. | Passive needle guard for syringes |
| JP4795611B2 (ja) | 2000-05-15 | 2011-10-19 | アレス トレーディング ソシエテ アノニム | 少なくとも１つの皮下注射針のための保持容器 |
| US6716198B2 (en) | 2000-05-18 | 2004-04-06 | Novo Nordisk A/S | Injection device |
| US6740062B2 (en) | 2000-05-22 | 2004-05-25 | Pharmacia Ab | Medical device |
| US6517517B1 (en) | 2000-06-08 | 2003-02-11 | Mayo Foundation For Medical Education And Research | Automated injection device for administration of liquid medicament |
| US6585690B1 (en) | 2000-06-29 | 2003-07-01 | Becton Dickinson And Company | Hypodermic syringe with selectivity retractable needle |
| AUPQ867900A0 (en) | 2000-07-10 | 2000-08-03 | Medrad, Inc. | Medical injector system |
| US6986760B2 (en) | 2000-08-02 | 2006-01-17 | Becton, Dickinson And Company | Pen needle and safety shield system |
| FR2812817B1 (fr) | 2000-08-09 | 2002-10-31 | Sanofi Synthelabo | Dispositif de protection d'une aiguille de seringue |
| US20020032412A1 (en) | 2000-08-24 | 2002-03-14 | John Riemelmoser | Syringe with retractable needle and a single use syringe |
| WO2002017996A1 (en) | 2000-08-29 | 2002-03-07 | Novo Nordisk A/S | Automatic injection device with torsion function for retraction of needle |
| CA2422692A1 (en) | 2000-09-21 | 2002-03-28 | Elan Pharma International Limited | Reconstitution and injection system |
| JP3941366B2 (ja) | 2000-09-22 | 2007-07-04 | フジノン株式会社 | 注射筒装置のストッパ |
| DE10047637A1 (de) | 2000-09-26 | 2002-04-25 | Disetronic Licensing Ag | Vorrichtung zur Verabreichung eines injizierbaren Produkts |
| FR2815543B1 (fr) | 2000-10-19 | 2003-10-24 | Sedat | Seringue d'auto-injection d'un melange extemporane |
| WO2002040854A1 (fr) | 2000-11-17 | 2002-05-23 | Isuzu Motors Limited | Dispositif amortisseur de levee de pointeau pour injecteur de carburant et procede d'amortissement de levee de pointeau |
| IT1320104B1 (it) | 2000-11-27 | 2003-11-18 | Paolo Versini | Dispositivo iniettore per trattamenti medici e cosmetici. |
| US6569085B2 (en) | 2001-08-16 | 2003-05-27 | Syntheon, Llc | Methods and apparatus for delivering a medical instrument over an endoscope while the endoscope is in a body lumen |
| SE518981C2 (sv) | 2000-12-14 | 2002-12-17 | Shl Medical Ab | Autoinjektor |
| US6387078B1 (en) | 2000-12-21 | 2002-05-14 | Gillespie, Iii Richard D. | Automatic mixing and injecting apparatus |
| US6485460B2 (en) | 2001-01-12 | 2002-11-26 | Bracco Diagnostics, Inc. | Tamper evident syringe barrel |
| DE60212799T2 (de) | 2001-01-18 | 2006-11-09 | Medrad, Inc. | Spritzenanschlussflächen und adaptern für verwendung mit medizinische injektoren |
| US6811545B2 (en) | 2001-01-31 | 2004-11-02 | Vincent L. Vaillancourt | Safety needle |
| US6673049B2 (en) | 2001-02-15 | 2004-01-06 | Disetronic Licensing Ag | Injection device for injecting fluid |
| US6471669B2 (en) | 2001-03-05 | 2002-10-29 | Bioject Medical Technologies Inc. | Disposable needle-free injection apparatus and method |
| US6645170B2 (en) | 2001-03-05 | 2003-11-11 | Bioject Medical Technologies, Inc. | Simplified disposable needle-free injection apparatus and method |
| EP1372756A4 (en) | 2001-03-13 | 2008-05-21 | Mdc Invest Holdings Inc | INJECTION DEVICE WITH PRE-FILLED AMPUL |
| MXPA03008004A (es) | 2001-03-15 | 2004-10-15 | Mdc Invest Holdings Inc | Dispositivo medico de aguja retraible para inyectar fluido desde un cartucho prellenado. |
| EP1383560B2 (de) * | 2001-04-06 | 2023-04-26 | F. Hoffmann-La Roche AG | Infusionsset |
| GB0109001D0 (en) | 2001-04-10 | 2001-05-30 | Glaxo Group Ltd | Dispenser |
| GB0109002D0 (en) | 2001-04-10 | 2001-05-30 | Glaxo Group Ltd | Dispenser |
| WO2002087663A2 (en) | 2001-04-27 | 2002-11-07 | Penjet Corporation | Method and apparatus for filling or refilling a needle-less injector |
| EP1392377B1 (en) | 2001-05-16 | 2007-02-28 | Eli Lilly And Company | Medication injector apparatus with drive assembly that facilitates reset |
| US6648850B2 (en) | 2001-06-08 | 2003-11-18 | Bioject, Inc. | Durable needle-less jet injector apparatus and method |
| EP3047863B1 (en) | 2001-07-09 | 2018-05-16 | Becton, Dickinson and Company | Needle shield assembly having hinged needle shield and flexible cannula lock |
| DE10137962A1 (de) | 2001-08-07 | 2003-02-20 | Roesch Ag Medizintechnik | Ampulle für eine Injektionseinrichtung |
| EP1425058A1 (en) | 2001-08-09 | 2004-06-09 | Becton Dickinson and Company | Retracting needle safety device |
| GB0119520D0 (en) | 2001-08-10 | 2001-10-03 | Owen Mumford Ltd | Improvements relating to injection devices |
| DE10140704A1 (de) | 2001-08-18 | 2003-03-06 | Vetter & Co Apotheker | Verfahren zur Durchmischung einer schwer löslichen pharmazeutischen Substanz mit einem Lösungsmittel und Spritze zur Anwendung des Verfahrens |
| US7235063B2 (en) | 2001-08-21 | 2007-06-26 | D'antonio Consultants International, Inc. | Hypodermic injection system |
| US7488306B2 (en) | 2001-09-26 | 2009-02-10 | Smiths Medical Asd, Inc. | Needle protection device with dampener |
| US7186241B2 (en) | 2001-10-03 | 2007-03-06 | Medical Instill Technologies, Inc. | Syringe with needle penetrable and laser resealable stopper |
| FR2830765B1 (fr) | 2001-10-15 | 2004-07-23 | Plastic Omnium Cie | Dispositif de securite pour une seringue |
| US6796967B2 (en) | 2001-10-22 | 2004-09-28 | Nps Pharmaceuticals, Inc. | Injection needle assembly |
| US7569035B1 (en) | 2001-11-02 | 2009-08-04 | Meridian Medical Technologies, Inc. | Automatic injector with anti-coring needle |
| ES2408971T3 (es) | 2001-11-09 | 2013-06-24 | Alza Corporation | Autoinyector neumático |
| WO2003041770A2 (en) | 2001-11-09 | 2003-05-22 | Alza Corporation | Collapsible syringe cartridge |
| US6607510B2 (en) | 2001-11-09 | 2003-08-19 | Bioject Medical Technologies Inc. | Disposable needle-free injection apparatus and method |
| DE10253637A1 (de) | 2001-11-14 | 2003-11-06 | Riemser Arzneimittel Ag | Injektionseinrichtung und Ampulle insbesondere für eine Injektionseinrichtung |
| JP4008232B2 (ja) | 2001-11-22 | 2007-11-14 | 昭和薬品化工株式会社 | 歯科用カートリッジ式電動注射器のプランジャロッドのプランジャヘッド |
| US20030105430A1 (en) | 2001-11-30 | 2003-06-05 | Elan Pharma International Limited Wil House | Automatic injector |
| US6863659B2 (en) | 2001-12-10 | 2005-03-08 | Bruce George Sharpe | Sharp safe hydraulic retractable syringe |
| WO2003051423A2 (en) | 2001-12-13 | 2003-06-26 | Becton Dickinson And Company | Needle closure system removal device |
| JP4046998B2 (ja) | 2001-12-14 | 2008-02-13 | ロレアル | 塗布具 |
| AU2002349253A1 (en) | 2001-12-19 | 2003-06-30 | Disetronic Licensing Ag | Administration device comprising an expulsion member and a stopper covering |
| US20040143224A1 (en) | 2002-01-07 | 2004-07-22 | Jeffrey Field | Method and apparatus for inhibiting fluid loss from a syringe |
| GB0200444D0 (en) | 2002-01-10 | 2002-02-27 | Owen Mumford Ltd | Improvements relating to medical injection devices |
| US6875205B2 (en) | 2002-02-08 | 2005-04-05 | Alaris Medical Systems, Inc. | Vial adapter having a needle-free valve for use with vial closures of different sizes |
| WO2003068290A2 (en) | 2002-02-11 | 2003-08-21 | Antares Pharma, Inc. | Intradermal injector |
| DE10207276A1 (de) | 2002-02-21 | 2003-09-11 | Disetronic Licensing Ag | Nadel-Insertionsvorrichtung mit quer bewegbarem Halteelement |
| GB0204673D0 (en) | 2002-02-28 | 2002-04-10 | Dca Design Int Ltd | Improvements in and relating to a medicament delivery device |
| GB0206560D0 (en) | 2002-03-20 | 2002-05-01 | Glaxo Group Ltd | Novel device |
| AU2003201335B2 (en) | 2002-03-20 | 2009-07-23 | Becton, Dickinson And Company | Shieldable needle assembly with biased safety shield |
| JP4039876B2 (ja) | 2002-03-27 | 2008-01-30 | テルモ株式会社 | 薬液注入装置 |
| JP2003298253A (ja) | 2002-03-29 | 2003-10-17 | Denso Corp | 電子制御装置の筐体構造及び電子制御装置の搭載構造 |
| US6912417B1 (en) | 2002-04-05 | 2005-06-28 | Ichor Medical Systmes, Inc. | Method and apparatus for delivery of therapeutic agents |
| AU2002332492A1 (en) | 2002-04-19 | 2003-11-03 | Equidyne Systems, Inc. | Multi-component ampule |
| US20030199814A1 (en) | 2002-04-19 | 2003-10-23 | Parsons J. Stuart | Multi-component ampule |
| CA2480972C (en) | 2002-04-24 | 2010-12-07 | Ares Trading Sa | Device for preparing a medicinal liquid and method for preserving a solution of medicament for injection |
| GB2388033A (en) | 2002-05-02 | 2003-11-05 | Pa Consulting Services | Automatic injection device |
| GB2396298A (en) | 2002-12-17 | 2004-06-23 | Pa Consulting Services | Injection device and drive coupling |
| BRPI0309876A2 (pt) | 2002-05-02 | 2017-03-28 | Pa Knowledge Ltd | dispositivo de injeção |
| US7207973B2 (en) | 2002-05-10 | 2007-04-24 | Becton, Dickinson And Company | Passive safety shield system for injection devices |
| US6776777B2 (en) | 2002-05-10 | 2004-08-17 | Becton, Dickinson And Company | Passive safety shield system for injection devices |
| US6808507B2 (en) | 2002-05-10 | 2004-10-26 | Cambridge Biostability Ltd. | Safety injectors |
| GB0211294D0 (en) | 2002-05-17 | 2002-06-26 | Owen Mumford Ltd | Improvements relating to injection devices |
| US6979316B1 (en) | 2002-05-23 | 2005-12-27 | Seedlings Life Science Ventures Llc | Apparatus and method for rapid auto-injection of medication |
| US6676630B2 (en) | 2002-06-04 | 2004-01-13 | Bioject Medical Technologies, Inc. | Needle-free injection system |
| US7156823B2 (en) | 2002-06-04 | 2007-01-02 | Bioject Inc. | High workload needle-free injection system |
| US20030229308A1 (en) | 2002-06-05 | 2003-12-11 | Israil Tsals | Injector adapter and combination thereof |
| US6764465B2 (en) | 2002-06-24 | 2004-07-20 | Long Hsiung Chen | Syringe with retractable needle and safety lock |
| MY139059A (en) | 2002-06-24 | 2009-08-28 | Alza Corp | Reusable, spring driven autoinjector |
| CN100462111C (zh) | 2002-07-02 | 2009-02-18 | 松下电器产业株式会社 | 医用自动给药器 |
| CA2492980A1 (en) | 2002-07-16 | 2004-01-22 | Eyegene Inc. | Protein for diagnosing diabetic retinopathy |
| TW572761B (en) | 2002-07-17 | 2004-01-21 | Ming-Jeng Shiu | Syringe with retraction force |
| WO2004011065A1 (en) | 2002-07-31 | 2004-02-05 | Alza Corporation | Injection device providing automatic needle retraction |
| US20040087897A1 (en) | 2002-07-31 | 2004-05-06 | Birger Hjertman | Device and method for liquid jet generation |
| GB2421689B (en) | 2002-08-05 | 2007-03-07 | Caretek Medical Ltd | Drug delivery system |
| FR2845052B1 (fr) | 2002-08-06 | 2005-06-24 | Fico Mirrors | Ensemble pour la liaison articulee d'un miroir retroviseur |
| US7083600B2 (en) | 2002-08-08 | 2006-08-01 | Advanced Medical Sharps, Inc. | Safety needle and shield |
| US7387623B2 (en) | 2002-08-21 | 2008-06-17 | Pfizer Inc. | Injectable pharmaceutical suspension in a two-chamber vial |
| US9486581B2 (en) | 2002-09-11 | 2016-11-08 | Becton, Dickinson And Company | Injector device with force lock-out and injection rate limiting mechanisms |
| US7160913B2 (en) | 2002-09-13 | 2007-01-09 | Thomas Jefferson University | Methods and kit for treating Parkinson's disease |
| EP1401089A1 (de) | 2002-09-18 | 2004-03-24 | Continental ISAD Electronic Systems GmbH & Co. KG | Elektrische Maschine, ausgebildet als Starter, Generator oder Starter-Generator für ein Kraftfahrzeug |
| WO2004028598A1 (en) * | 2002-09-24 | 2004-04-08 | Shl Medical Ab | Injecting device |
| GB0222731D0 (en) | 2002-10-01 | 2002-11-06 | Parker David W | Improvements in or relating to hypodermic syringes |
| DE10248061A1 (de) | 2002-10-15 | 2004-05-06 | Disetronic Licensing Ag | Injektionsvorrichtung mit Leerhub |
| GB0224505D0 (en) * | 2002-10-22 | 2002-11-27 | Medical House The Plc | Needles injection device |
| US6939319B1 (en) | 2002-11-20 | 2005-09-06 | Conrad Anstead | Process and device for single use, needle-free intradermal, subcutaneous, or intramuscular injections |
| KR20040043896A (ko) | 2002-11-20 | 2004-05-27 | 삼성전자주식회사 | 푸시버튼 |
| EP1572271A1 (de) | 2002-11-25 | 2005-09-14 | Tecpharma Licensing AG | Autoinjektor mit rückstellbarer auslösesicherung |
| CH695926A5 (de) | 2002-11-25 | 2006-10-31 | Tecpharma Licensing Ag | Vorrichtung zum automatischen Injizieren eines Wirkstoffes. |
| CH696186A5 (de) | 2002-11-25 | 2007-02-15 | Tecpharma Licensing Ag | Vorrichtung zur Sicherung von Injektionsnadeln. |
| EP1572268A1 (de) | 2002-11-25 | 2005-09-14 | Tecpharma Licensing AG | Vorrichtung zum automatischen injizieren eines wirkstoffes |
| JP4339260B2 (ja) | 2002-11-25 | 2009-10-07 | テクファーマ・ライセンシング・アクチェンゲゼルシャフト | 針保護装置を有する注射装置 |
| GB0228483D0 (en) | 2002-12-06 | 2003-01-08 | Boots Healthcare Int Ltd | Bottle |
| US6939330B1 (en) | 2002-12-12 | 2005-09-06 | Medsolve Llc | Syringe insertion system |
| GB2396816A (en) | 2002-12-17 | 2004-07-07 | Pa Consulting Services | Injection device |
| GB0229345D0 (en) | 2002-12-17 | 2003-01-22 | Safe T Ltd | Hollow needle applicators |
| US7252651B2 (en) | 2003-01-07 | 2007-08-07 | Becton, Dickinson And Company | Disposable injection device |
| US6767336B1 (en) | 2003-01-09 | 2004-07-27 | Sheldon Kaplan | Automatic injector |
| ES2344896T3 (es) | 2003-01-22 | 2010-09-09 | Duoject Medical Systems Inc | Sistemas de suministro de producto farmaceutico. |
| US7678333B2 (en) | 2003-01-22 | 2010-03-16 | Duoject Medical Systems Inc. | Fluid transfer assembly for pharmaceutical delivery system and method for using same |
| US20060104968A1 (en) | 2003-03-05 | 2006-05-18 | Halozyme, Inc. | Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases |
| FR2852851B1 (fr) | 2003-03-25 | 2006-01-06 | Sedat | Dispositif de protection d'aiguille destine a une seringue, et dispositif d'injection comprenant une seringue et ce dispositif de protection |
| US7115114B2 (en) | 2003-05-02 | 2006-10-03 | Becton, Dickinson And Company | Medical device having releasable retainer |
| US6805686B1 (en) | 2003-05-06 | 2004-10-19 | Abbott Laboratories | Autoinjector with extendable needle protector shroud |
| JP2007518460A (ja) | 2003-05-09 | 2007-07-12 | イントラヴァック インコーポレーテッド | 皮内、皮下及び筋肉内注射用の無針注射器及びアンプル |
| GB0312852D0 (en) | 2003-06-05 | 2003-07-09 | Owen Mumford Ltd | Improvements relating to syringe firing mechanisms |
| BRPI0411212A (pt) | 2003-06-09 | 2006-07-18 | Nipro Diabetes Systems Inc | sistema de liberação de lìquido |
| DE10327254B4 (de) | 2003-06-17 | 2010-01-28 | Disetronic Licensing Ag | Modulare Infusionspumpe |
| DE50307239D1 (de) | 2003-06-25 | 2007-06-21 | Mueller Martini Holding Ag | Ausschleuseinrichtung |
| GB2403711A (en) | 2003-07-07 | 2005-01-12 | Gw Pharma Ltd | Drug dispenser with controlled access |
| JP3883527B2 (ja) | 2003-07-17 | 2007-02-21 | ニプロ株式会社 | トランスファーニードル |
| US7500963B2 (en) | 2003-07-22 | 2009-03-10 | Safety Syringes, Inc. | Systems and methods for automatic medical injection with safeguard |
| GB2404338B (en) | 2003-07-30 | 2007-01-24 | Safe T Ltd | Actuator and containment device for a syringe |
| US20050027255A1 (en) | 2003-07-31 | 2005-02-03 | Sid Technologies, Llc | Automatic injector |
| DE20311996U1 (de) | 2003-08-01 | 2003-10-16 | Hoelzle Dieter Tech Projekte | Injektionsvorrichtung |
| US8932264B2 (en) | 2003-08-11 | 2015-01-13 | Becton, Dickinson And Company | Medication delivery pen assembly with needle locking safety shield |
| DE10339794A1 (de) | 2003-08-28 | 2005-04-07 | Tecpharma Licensing Ag | Verabreichungsvorrichtung mit einer Schutzkappenabziehvorrichtung und einer Nadelschutzhülsenblockiereinrichtung |
| DE10340586A1 (de) | 2003-09-03 | 2005-04-07 | Tecpharma Licensing Ag | Abmischvorrichtung für Mehrkammerampulle |
| DE10342058B4 (de) | 2003-09-11 | 2007-10-25 | Tecpharma Licensing Ag | Verabreichungsvorrichtung für ein injizierbares Produkt mit einer Auslösesicherung |
| US7097071B2 (en) | 2003-09-16 | 2006-08-29 | Mark L Anderson | Dispenser container technology |
| IL157981A (en) | 2003-09-17 | 2014-01-30 | Elcam Medical Agricultural Cooperative Ass Ltd | Auto injector |
| FR2860162B1 (fr) | 2003-09-26 | 2006-06-02 | Becton Dickinson France | Dispositif de protection d'un appareil d'injection |
| US20050085776A1 (en) | 2003-10-16 | 2005-04-21 | Edgar Hommann | Injection device for administering a fluid product |
| DE10348185A1 (de) | 2003-10-16 | 2005-05-19 | Tecpharma Licensing Ag | Injektionsgerät mit Nadelabdeckung |
| EP1698365A3 (en) | 2003-10-16 | 2006-09-20 | Tecpharma Licensing AG | Injection device for administering a fluid product |
| JP2005141729A (ja) | 2003-10-17 | 2005-06-02 | Fuji Xerox Co Ltd | 周辺機器制御プログラム、装置および方法、並びに表示制御プログラム、装置および方法 |
| FR2861310B1 (fr) | 2003-10-22 | 2006-09-22 | Plastef Investissements | Dispositif de seringue d'injection securise |
| DE10351598A1 (de) | 2003-11-05 | 2005-06-16 | Tecpharma Licensing Ag | Autoinjektionsvorrichtung |
| DE10351599A1 (de) | 2003-11-05 | 2005-06-16 | Tecpharma Licensing Ag | Autoinjektionsvorrichtung |
| US20050101919A1 (en) | 2003-11-07 | 2005-05-12 | Lennart Brunnberg | Device for an injector |
| US20050125019A1 (en) | 2003-12-05 | 2005-06-09 | Paul Kudrna | Lancet device and method |
| CA2546468C (en) | 2003-12-05 | 2015-05-26 | Aradigm Corporation | A device for readying a needle free injector for delivery |
| CH696421A5 (de) | 2003-12-18 | 2007-06-15 | Tecpharma Licensing Ag | Autoinjektor mit Arretierung des Wirkstoffbehälters. |
| WO2005058396A1 (de) | 2003-12-18 | 2005-06-30 | Tecpharma Licensing Ag | Auslösbares injektionsgerät |
| US20050137523A1 (en) | 2003-12-22 | 2005-06-23 | Wyatt Philip W. | Medicament administration apparatus |
| ES2296129T3 (es) | 2004-01-23 | 2008-04-16 | The Medical House Plc | Dispositivo de inyeccion. |
| GB2410188B (en) | 2004-01-23 | 2006-01-25 | Medical House Plc | Injection device |
| FR2865407B1 (fr) | 2004-01-27 | 2006-04-28 | Crossject | Seringue sans aiguille avec un injecteur receptacle amortissant |
| US7717879B2 (en) | 2004-02-03 | 2010-05-18 | Smjm Inject Gmbh | Anesthetic syringe |
| US20050209554A1 (en) | 2004-03-19 | 2005-09-22 | Sergio Landau | Needle-free single-use cartridge and injection system |
| WO2005095391A1 (en) | 2004-03-24 | 2005-10-13 | Array Biopharma Inc. | Thiazoliums as transketolase inhibitors |
| US20050222539A1 (en) | 2004-03-30 | 2005-10-06 | Pediamed Pharmaceuticals, Inc. | Automatic injection device |
| IL161660A0 (en) | 2004-04-29 | 2004-09-27 | Medimop Medical Projects Ltd | Liquid drug delivery device |
| NL1026187C2 (nl) | 2004-05-13 | 2005-11-15 | Univ Eindhoven Tech | Inrichting voor het genereren van corona-ontladingen. |
| US20050261633A1 (en) * | 2004-05-19 | 2005-11-24 | Khalaj Ben M | Rechargeable handheld injection device with reversible drive having adjustable syringe cradle |
| US7717874B2 (en) | 2004-05-28 | 2010-05-18 | Bioject, Inc. | Needle-free injection system |
| GB2414398B (en) | 2004-05-28 | 2009-04-22 | Cilag Ag Int | Injection device |
| GB2414404B (en) | 2004-05-28 | 2009-06-03 | Cilag Ag Int | Injection device |
| PL1755712T3 (pl) | 2004-05-28 | 2018-06-29 | Cilag Gmbh International | Urządzenie do iniekcji |
| GB2414775B (en) | 2004-05-28 | 2008-05-21 | Cilag Ag Int | Releasable coupling and injection device |
| GB2414401B (en) | 2004-05-28 | 2009-06-17 | Cilag Ag Int | Injection device |
| GB2414406B (en) | 2004-05-28 | 2009-03-18 | Cilag Ag Int | Injection device |
| DE102004026745B4 (de) | 2004-05-28 | 2013-06-20 | Justus-Liebig-Universität Giessen | Verfahren und Vorrichtung zur Ausbringung von nanoskaligen Polymerfasern als Träger für landwirtschaftliche Wirkstoffe |
| GB2414409B (en) | 2004-05-28 | 2009-11-18 | Cilag Ag Int | Injection device |
| GB2414405B (en) | 2004-05-28 | 2009-01-14 | Cilag Ag Int | Injection device |
| GB2414399B (en) | 2004-05-28 | 2008-12-31 | Cilag Ag Int | Injection device |
| GB2414400B (en) | 2004-05-28 | 2009-01-14 | Cilag Ag Int | Injection device |
| US20050273054A1 (en) | 2004-06-03 | 2005-12-08 | Florida Atlantic University | Epinephrine auto-injector |
| ITMI20041471A1 (it) | 2004-07-21 | 2004-10-21 | Sergio Restelli | Kit di sicurezza per siringa standard relativa a siringa monouso di sicurezza |
| US20060100588A1 (en) | 2004-07-23 | 2006-05-11 | Lennart Brunnberg | Needle handling device |
| US7449012B2 (en) | 2004-08-06 | 2008-11-11 | Meridian Medical Technologies, Inc. | Automatic injector |
| US20060069350A1 (en) | 2004-09-30 | 2006-03-30 | Buenger David R | Medical syringe injector pen |
| US7731678B2 (en) | 2004-10-13 | 2010-06-08 | Hyprotek, Inc. | Syringe devices and methods for mixing and administering medication |
| US20060089594A1 (en) | 2004-10-26 | 2006-04-27 | Sergio Landau | Needle-free injection device |
| US20060089593A1 (en) | 2004-10-26 | 2006-04-27 | Sergio Landau | Needle-free injection device for individual users |
| US7255689B2 (en) | 2004-10-29 | 2007-08-14 | Safety Syringes, Inc. | Syringe with anti-rotation for luer lock |
| US7666168B2 (en) | 2004-11-05 | 2010-02-23 | Don Millerd | Syringe guard with selected needle configurations |
| US7412273B2 (en) | 2004-11-15 | 2008-08-12 | Biosense Webster, Inc. | Soft linear mapping catheter with stabilizing tip |
| US7297136B2 (en) | 2004-12-06 | 2007-11-20 | Wyrick Ronald E | Medicine injection devices and methods |
| US7905352B2 (en) | 2004-12-06 | 2011-03-15 | Washington Biotech Corporation | Kits containing medicine injection devices and containers |
| MX2007006975A (es) | 2004-12-09 | 2007-08-15 | West Pharm Serv Inc | Jeringa con aguja fija con retrocarga y dispositivo de inyeccion automatica del mismo. |
| US7407494B2 (en) | 2005-01-31 | 2008-08-05 | Bostroem Anders | Device for delivering medicament |
| US8361026B2 (en) | 2005-02-01 | 2013-01-29 | Intelliject, Inc. | Apparatus and methods for self-administration of vaccines and other medicaments |
| US20060258986A1 (en) | 2005-02-11 | 2006-11-16 | Hunter Ian W | Controlled needle-free transport |
| US20060184103A1 (en) | 2005-02-17 | 2006-08-17 | West Pharmaceutical Services, Inc. | Syringe safety device |
| DE102005007614A1 (de) | 2005-02-18 | 2006-08-24 | Tecpharma Licensing Ag | Autoinjektor mit einer Auslöseverriegelung |
| US20070060904A1 (en) | 2005-03-14 | 2007-03-15 | Becton, Dickinson And Company | Filling system and method for syringes with short needles |
| GB2425062B (en) | 2005-04-06 | 2010-07-21 | Cilag Ag Int | Injection device |
| GB2424835B (en) | 2005-04-06 | 2010-06-09 | Cilag Ag Int | Injection device (modified trigger) |
| GB2424837B (en) | 2005-04-06 | 2010-10-06 | Cilag Ag Int | Injection device |
| GB2427826B (en) | 2005-04-06 | 2010-08-25 | Cilag Ag Int | Injection device comprising a locking mechanism associated with integrally formed biasing means |
| GB2424838B (en) | 2005-04-06 | 2011-02-23 | Cilag Ag Int | Injection device (adaptable drive) |
| GB2424836B (en) | 2005-04-06 | 2010-09-22 | Cilag Ag Int | Injection device (bayonet cap removal) |
| FR2884721A1 (fr) | 2005-04-20 | 2006-10-27 | Becton Dickinson France Soc Pa | Ensemble d'injection et dispositif d'assistance a l'injection |
| US7618393B2 (en) | 2005-05-03 | 2009-11-17 | Pharmajet, Inc. | Needle-less injector and method of fluid delivery |
| US7699802B2 (en) | 2005-05-03 | 2010-04-20 | Pharmajet, Inc. | Needle-less injector |
| EP1904131A2 (en) | 2005-06-21 | 2008-04-02 | Eli Lilly And Company | Apparatus and method for injecting a pharmaceutical |
| EP1759729B1 (en) | 2005-08-30 | 2009-12-23 | Cilag GmbH International | Needle assembly for a prefilled syringe system |
| WO2007035564A2 (en) | 2005-09-19 | 2007-03-29 | Lifescan, Inc. | Malfunction detection with derivative calculation |
| US20110098656A1 (en) | 2005-09-27 | 2011-04-28 | Burnell Rosie L | Auto-injection device with needle protecting cap having outer and inner sleeves |
| AU2006304009A1 (en) | 2005-10-11 | 2007-04-26 | Eli Lilly And Company | Apparatus for injecting a pharmaceutical |
| US20080249462A1 (en) | 2005-10-21 | 2008-10-09 | Nilufer Smith Innovations Limited | Disposable Dispensers for Personal Use |
| US7682155B2 (en) | 2005-11-03 | 2010-03-23 | Meridian Medical Technologies, Inc. | Training device for an automatic injector |
| DE102005052502A1 (de) | 2005-11-03 | 2007-05-16 | Tecpharma Licensing Ag | Autoinjektor-Aktivierung Auslöseelement |
| US7988675B2 (en) * | 2005-12-08 | 2011-08-02 | West Pharmaceutical Services Of Delaware, Inc. | Automatic injection and retraction devices for use with pre-filled syringe cartridges |
| GB2433032A (en) | 2005-12-08 | 2007-06-13 | Owen Mumford Ltd | Syringe with dose adjustment means |
| US7657849B2 (en) | 2005-12-23 | 2010-02-02 | Apple Inc. | Unlocking a device by performing gestures on an unlock image |
| US7981101B2 (en) | 2005-12-30 | 2011-07-19 | Carefusion 303, Inc. | Medical vial adapter with reduced diameter cannula and enlarged vent lumen |
| US8926562B2 (en) | 2005-12-30 | 2015-01-06 | Hospira, Inc. | Syringe holding system |
| GB0601309D0 (en) | 2006-01-23 | 2006-03-01 | Medical House The Plc | Injection device |
| JP4741952B2 (ja) | 2006-02-02 | 2011-08-10 | Ｉｄｅｃ株式会社 | 操作スイッチ |
| GB0604459D0 (en) | 2006-03-06 | 2006-04-12 | Gramplan Health Board | Needle guidance apparatus |
| FR2899482A1 (fr) | 2006-04-11 | 2007-10-12 | Becton Dickinson France Soc Pa | Dispositif d'injection automatique |
| US7547300B2 (en) | 2006-04-12 | 2009-06-16 | Icu Medical, Inc. | Vial adaptor for regulating pressure |
| CN101426543A (zh) | 2006-04-21 | 2009-05-06 | 诺沃-诺迪斯克有限公司 | 两级射流注射设备 |
| WO2007131013A1 (en) | 2006-05-03 | 2007-11-15 | Antares Pharma, Inc. | Two-stage reconstituting injector |
| WO2007129324A2 (en) | 2006-05-09 | 2007-11-15 | Gil Yigal | A disposable injecting device with auto-retraction mechanism |
| GB2465919B (en) | 2006-05-10 | 2010-12-08 | Owen Mumford Ltd | Injection device with cap that can be re-fitted post injection |
| GB2438590B (en) | 2006-06-01 | 2011-02-09 | Cilag Gmbh Int | Injection device |
| GB2438629B (en) | 2006-06-01 | 2011-02-23 | Cilag Gmbh Int | Injection device |
| GB2438591B (en) | 2006-06-01 | 2011-07-13 | Cilag Gmbh Int | Injection device |
| GB2438593B (en) | 2006-06-01 | 2011-03-30 | Cilag Gmbh Int | Injection device (cap removal feature) |
| US7618396B2 (en) | 2006-08-09 | 2009-11-17 | Avant Medical Corp. | Injection system with hidden needles |
| US7811262B2 (en) | 2006-08-23 | 2010-10-12 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir filling and infusion medium delivery |
| US7794434B2 (en) | 2006-08-23 | 2010-09-14 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir filling and infusion medium delivery |
| US7828764B2 (en) | 2006-08-23 | 2010-11-09 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir filling and infusion medium delivery |
| US8167863B2 (en) | 2006-10-16 | 2012-05-01 | Carefusion 303, Inc. | Vented vial adapter with filter for aerosol retention |
| CA2564061A1 (en) | 2006-10-16 | 2008-04-16 | Duoject Medical Systems Inc. | Reconstitution system for mixing the contents of a vial containing a first substance with a second substance stored in a cartridge |
| US9345831B2 (en) | 2006-10-19 | 2016-05-24 | E3D Agricultural Cooperative Association Ltd | Automatic injection device |
| GB2443606B (en) | 2006-11-13 | 2011-07-20 | Cilag Gmbh Int | Injection device |
| ES2365931T3 (es) | 2006-12-13 | 2011-10-13 | Shl Group Ab | Inyector automático. |
| GB0625169D0 (en) | 2006-12-18 | 2007-01-24 | Medical House Plc The | Improved autoinjector |
| BRPI0720777A2 (pt) * | 2006-12-22 | 2014-07-01 | Novo Nordisk As | Conjunto de agulha capaz de ser protegido com protetor inclinado de segurança |
| US7871397B2 (en) | 2006-12-26 | 2011-01-18 | Stat Medical Devices, Inc. | Pen needle tip |
| WO2008093063A2 (en) | 2007-02-01 | 2008-08-07 | Pa Knowledge Limited | Auto injector and adaptor for covering the needle of the auto injector |
| GB2446778A (en) | 2007-02-01 | 2008-08-27 | Pa Knowledge Ltd | Syringe adaptor |
| US7883499B2 (en) | 2007-03-09 | 2011-02-08 | Icu Medical, Inc. | Vial adaptors and vials for regulating pressure |
| WO2008112472A2 (en) * | 2007-03-09 | 2008-09-18 | Eli Lilly And Company | Delay mechanism for automatic injection device |
| CN101674857A (zh) | 2007-03-22 | 2010-03-17 | 特克法马许可公司 | 具有触发保险的注射装置 |
| AU2008231910B2 (en) | 2007-03-23 | 2011-04-14 | Shl Group Ab | Auto injector |
| BRPI0810582A2 (pt) | 2007-04-23 | 2015-10-27 | Program For Appropriate Technology In Health | métodos e dispositivos para injeção intradérmica |
| US8434528B2 (en) | 2007-04-30 | 2013-05-07 | Medtronic Minimed, Inc. | Systems and methods for reservoir filling |
| US7959715B2 (en) | 2007-04-30 | 2011-06-14 | Medtronic Minimed, Inc. | Systems and methods allowing for reservoir air bubble management |
| WO2008144575A2 (en) | 2007-05-18 | 2008-11-27 | Optiscan Biomedical Corporation | Fluid injection and safety system |
| JP4780034B2 (ja) | 2007-05-18 | 2011-09-28 | 株式会社島津製作所 | 針無注射器 |
| JP2008295590A (ja) | 2007-05-29 | 2008-12-11 | Terumo Corp | 穿刺器具 |
| US20080306443A1 (en) | 2007-06-06 | 2008-12-11 | Mallinckrodt Inc. | Medical Fluid Injector Having Wireless Pressure Monitoring Feature |
| CN101754779B (zh) | 2007-07-18 | 2012-09-05 | 优诺医疗有限公司 | 具有受控的加速度的插入装置 |
| GB2451665B (en) | 2007-08-08 | 2012-09-26 | Cilag Gmbh Int | Injection device |
| GB2451663B (en) | 2007-08-08 | 2012-09-26 | Cilag Gmbh Int | Injection device |
| GB2452286B (en) * | 2007-08-29 | 2012-09-26 | Cilag Gmbh Int | Injection system |
| WO2009040605A1 (en) | 2007-09-25 | 2009-04-02 | Becton Dickinson France | Autoinjector with trigger positionable in active position by movement of a safety shield and indication of the active position |
| WO2009062508A1 (en) | 2007-11-12 | 2009-05-22 | Bang & Olufsen Medicom A/S | Auto injector with a rotatable release shaft |
| CA2718053C (en) | 2008-03-10 | 2016-09-27 | Antares Pharma, Inc. | Injector safety device |
| GB2461088B (en) * | 2008-06-19 | 2012-09-26 | Cilag Gmbh Int | Injection device |
| GB2461089B (en) | 2008-06-19 | 2012-09-19 | Cilag Gmbh Int | Injection device |
| GB2461085B (en) | 2008-06-19 | 2012-08-29 | Cilag Gmbh Int | Injection device |
| GB2461087B (en) | 2008-06-19 | 2012-09-26 | Cilag Gmbh Int | Injection device |
| JP5603335B2 (ja) * | 2008-08-29 | 2014-10-08 | ノボ・ノルデイスク・エー／エス | 時間遅延インジケータを備える医療用注射器 |
| US8936578B2 (en) | 2008-09-18 | 2015-01-20 | Becton, Dickinson And Company | Medical injector with ratcheting plunger |
| EP2362795B1 (en) | 2008-09-29 | 2018-04-25 | Becton Dickinson France | Automatic injection device |
| SG193862A1 (en) | 2008-09-30 | 2013-10-30 | Terumo Corp | Injection needle and drug injection device |
| US8845592B2 (en) | 2008-12-12 | 2014-09-30 | Shl Group Ab | Medicament delivery device |
| EP2415493A4 (en) | 2009-03-30 | 2017-12-13 | Terumo Kabushiki Kaisha | Syringe needle assembly and medicament injection device |
| BRPI1010279A2 (pt) | 2009-03-31 | 2016-10-18 | Sanofi Aventis Deustschland Gmbh | dispositivo de distribuição de fármaco |
| GB2472578A (en) | 2009-08-10 | 2011-02-16 | Owen Mumford Ltd | Sheath removal device and needle protector |
| JP5728013B2 (ja) | 2009-08-27 | 2015-06-03 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 薬物送達デバイス用のハウジング部材 |
| JP5909188B2 (ja) | 2009-10-30 | 2016-04-26 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 薬物送達デバイスおよび組み立て方法 |
| US9248245B2 (en) | 2010-02-18 | 2016-02-02 | Sanofi-Aventis Deutschlannd GMBH | Auto-injector |
| WO2011109205A2 (en) * | 2010-03-01 | 2011-09-09 | Eli Lilly And Company | Automatic injection device with delay mechanism including dual functioning biasing member |
| JP5864528B2 (ja) | 2010-03-25 | 2016-02-17 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ニードルアセンブリ |
| JP6165055B2 (ja) | 2010-06-28 | 2017-07-19 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 自動注射器 |
| EP2399629A1 (en) | 2010-06-28 | 2011-12-28 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| EP2399628A1 (en) | 2010-06-28 | 2011-12-28 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| EP2399635A1 (en) | 2010-06-28 | 2011-12-28 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| EP2399633A1 (en) | 2010-06-28 | 2011-12-28 | Sanofi-Aventis Deutschland GmbH | Needle safety arrangement and method for operating it |
| BR112013000038B1 (pt) | 2010-07-02 | 2021-01-19 | Sanofi-Aventis Deutschland Gmbh | dispositivo de segurança para uma seringa pré-carregada e dispositivo de injeção |
| NZ604076A (en) | 2010-07-02 | 2014-05-30 | Sanofi Aventis Deutschland | Safety device for a pre-filled syringe and injection device |
| EP2588165B1 (en) | 2010-07-02 | 2020-06-17 | Sanofi-Aventis Deutschland GmbH | Safety device for a pre-filled syringe, injection device and injection kit |
| EP2446866A1 (en) | 2010-11-02 | 2012-05-02 | Fovea Pharmaceuticals | Apparatus for injection into an eye |
| EP2468332A1 (en) | 2010-12-21 | 2012-06-27 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| EP2468330A1 (en) | 2010-12-21 | 2012-06-27 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| DK2661299T3 (en) | 2011-01-04 | 2015-05-04 | Sanofi Aventis Deutschland | SAFETY DEVICE FOR A PRELIMED Syringe and Injection Device |
| EP2661292B1 (en) | 2011-01-04 | 2015-01-28 | Sanofi-Aventis Deutschland GmbH | A safety device for a pre-filled syringe and an injection device |
| EP2489380A1 (en) | 2011-02-18 | 2012-08-22 | Sanofi-Aventis Deutschland GmbH | Injection device |
| GB2488579A (en) * | 2011-03-02 | 2012-09-05 | Owen Mumford Ltd | Autoinjector with "injection complete" indicator |
| EP2510911A1 (en) | 2011-04-13 | 2012-10-17 | Sanofi-Aventis Deutschland GmbH | Apparatus for intraocular injection |
| EP3639870B1 (en) | 2011-05-12 | 2023-08-02 | Bayer Healthcare LLC | Fluid injection system having various systems for controlling an injection procedure |
| DK2720738T3 (en) | 2011-06-17 | 2016-04-18 | Sanofi Aventis Deutschland | Cartridge holder device for pharmaceutical feeding devices |
| US8881443B2 (en) | 2011-07-20 | 2014-11-11 | Intelligun, Llc | Firearm safety lock with key-based override |
| CN104667387B (zh) | 2011-08-31 | 2019-03-01 | Shl集团有限责任公司 | 注射装置 |
| US9821118B2 (en) | 2011-09-02 | 2017-11-21 | Unl Holdings Llc | Automatic reconstitution for dual chamber syringe |
| US9775948B2 (en) * | 2011-09-09 | 2017-10-03 | Merck Patent Gmbh | Auto injector with separate needle injection |
| JP6251172B2 (ja) | 2011-09-29 | 2017-12-20 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 薬物送達デバイスおよび薬物送達デバイスに対する方法 |
| EP2583706A1 (en) | 2011-10-21 | 2013-04-24 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
| WO2013070715A1 (en) | 2011-11-07 | 2013-05-16 | Battelle Memorial Institute | Injection devices with ergonomic enhancements |
| CN104125843A (zh) | 2012-01-10 | 2014-10-29 | 赛诺菲-安万特德国有限公司 | 用于皮内注射的引导组件 |
| CH703993A2 (de) | 2012-02-09 | 2012-03-15 | Tecpharma Licensing Ag | Injektionsgerät zur Verabreichung oder Förderung von fluidem Produkt. |
| SG10201700698WA (en) | 2012-05-15 | 2017-02-27 | Bristol Myers Squibb Co | Cancer immunotherapy by disrupting pd-1/pd-l1 signaling |
| EP2698179A1 (en) | 2012-08-14 | 2014-02-19 | Sanofi-Aventis Deutschland GmbH | Injection device |
| EP2705862B1 (en) | 2012-09-05 | 2015-07-08 | Becton Dickinson France | Automatic injection device |
| HUE026766T2 (en) | 2012-09-05 | 2016-07-28 | Becton Dickinson France | Automatic syringe device |
| GB2516784B (en) | 2013-06-11 | 2015-10-21 | Cilag Gmbh Int | Injection device |
-
2013
- 2013-06-11 GB GB1310402.1A patent/GB2517896B/en active Active
-
2014
- 2014-06-11 CN CN201480033329.6A patent/CN105358194B/zh active Active
- 2014-06-11 AU AU2014280155A patent/AU2014280155B2/en active Active
- 2014-06-11 KR KR1020167000443A patent/KR20160014767A/ko not_active Application Discontinuation
- 2014-06-11 MX MX2015017067A patent/MX2015017067A/es unknown
- 2014-06-11 ES ES14733564T patent/ES2949338T3/es active Active
- 2014-06-11 BR BR112015030850-3A patent/BR112015030850B1/pt active IP Right Grant
- 2014-06-11 CA CA2914852A patent/CA2914852C/en active Active
- 2014-06-11 SG SG11201510169QA patent/SG11201510169QA/en unknown
- 2014-06-11 EP EP14733564.0A patent/EP3007749B1/en active Active
- 2014-06-11 UA UAA201600165A patent/UA118193C2/uk unknown
- 2014-06-11 US US14/897,369 patent/US11123492B2/en active Active
- 2014-06-11 NZ NZ715358A patent/NZ715358A/en unknown
- 2014-06-11 JP JP2015563073A patent/JP5981057B2/ja active Active
- 2014-06-11 WO PCT/EP2014/062167 patent/WO2014198798A2/en active Application Filing
- 2014-06-11 EA EA201592311A patent/EA034009B1/ru unknown
-
2015
- 2015-09-01 HK HK15108513.4A patent/HK1207832A1/zh unknown
- 2015-11-30 IL IL242852A patent/IL242852A/en active IP Right Grant
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1893992A (zh) * | 2003-12-18 | 2007-01-10 | 诺沃挪第克公司 | 具有皮肤拉紧装置的喷嘴设备 |
| CN101014379A (zh) * | 2004-05-28 | 2007-08-08 | 西拉格国际有限公司 | 注射装置 |
| CN101005868B (zh) * | 2004-05-28 | 2010-11-17 | 西拉格国际有限公司 | 注射装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20160129195A1 (en) | 2016-05-12 |
| GB2517896A (en) | 2015-03-11 |
| JP2016521583A (ja) | 2016-07-25 |
| GB201310402D0 (en) | 2013-07-24 |
| NZ715358A (en) | 2018-09-28 |
| JP5981057B2 (ja) | 2016-08-31 |
| ES2949338T3 (es) | 2023-09-27 |
| BR112015030850A2 (pt) | 2017-07-25 |
| KR20160014767A (ko) | 2016-02-11 |
| SG11201510169QA (en) | 2016-01-28 |
| MX2015017067A (es) | 2016-04-21 |
| CN105358194A (zh) | 2016-02-24 |
| CA2914852A1 (en) | 2014-12-18 |
| BR112015030850B1 (pt) | 2022-11-01 |
| EA201592311A1 (ru) | 2016-05-31 |
| AU2014280155B2 (en) | 2016-01-28 |
| UA118193C2 (uk) | 2018-12-10 |
| EA034009B1 (ru) | 2019-12-18 |
| WO2014198798A4 (en) | 2015-05-14 |
| EP3007749A2 (en) | 2016-04-20 |
| EP3007749B1 (en) | 2023-06-07 |
| AU2014280155A1 (en) | 2015-12-24 |
| IL242852A (en) | 2017-06-29 |
| CA2914852C (en) | 2023-12-12 |
| HK1207832A1 (zh) | 2016-02-12 |
| US11123492B2 (en) | 2021-09-21 |
| GB2517896B (en) | 2015-07-08 |
| WO2014198798A2 (en) | 2014-12-18 |
| WO2014198798A3 (en) | 2015-03-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105358194B (zh) | 注射装置 | |
| CN104491955B (zh) | 安全式胰岛素笔针 | |
| US8740871B2 (en) | Preservative-free follicle stimulating hormone solution delivery device | |
| TWI558429B (zh) | 自動注射器（三） | |
| US10702663B2 (en) | Reconstitution means for safety device | |
| RU2607939C2 (ru) | Автоматический инъектор | |
| JP5807021B2 (ja) | 自動注射器 | |
| TW201109057A (en) | Medicated module with bypass and needle guard | |
| TW201247272A (en) | Auto-injector | |
| TW201109058A (en) | Medicated module with needle guard | |
| CA2915185C (en) | Injection device | |
| JP2021524300A (ja) | 注射デバイスおよび注射デバイス用の容器 | |
| US9636462B2 (en) | Drug delivery device with shield operated needle actuator | |
| TW202031308A (zh) | 用於注射裝置之包含暴露帽移除器的配件 | |
| TW202034974A (zh) | 包括用於注射裝置之凸緣之狹槽之輔助件 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |