US5866363A
(en)
*
|
1985-08-28 |
1999-02-02 |
Pieczenik; George |
Method and means for sorting and identifying biological information
|
US5824469A
(en)
*
|
1986-07-17 |
1998-10-20 |
University Of Washington |
Method for producing novel DNA sequences with biological activity
|
US20060008806A1
(en)
*
|
1986-07-17 |
2006-01-12 |
University Of Washington |
Method for producing novel DNA sequence with biological activity
|
US5266684A
(en)
|
1988-05-02 |
1993-11-30 |
The Reagents Of The University Of California |
Peptide mixtures
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
CA2009996A1
(en)
*
|
1989-02-17 |
1990-08-17 |
Kathleen S. Cook |
Process for making genes encoding random polymers of amino acids
|
US7413537B2
(en)
|
1989-09-01 |
2008-08-19 |
Dyax Corp. |
Directed evolution of disulfide-bonded micro-proteins
|
DE69032483T2
(de)
*
|
1989-10-05 |
1998-11-26 |
Optein, Inc., Seattle, Wash. |
Zellfreie synthese und isolierung von genen und polypeptiden
|
US5498538A
(en)
*
|
1990-02-15 |
1996-03-12 |
The University Of North Carolina At Chapel Hill |
Totally synthetic affinity reagents
|
US5747334A
(en)
*
|
1990-02-15 |
1998-05-05 |
The University Of North Carolina At Chapel Hill |
Random peptide library
|
EP0515516B1
(en)
*
|
1990-02-15 |
2002-01-16 |
University of North Carolina |
Methods for identifying heterofunctional fusion proteins
|
US5639595A
(en)
*
|
1990-05-01 |
1997-06-17 |
Isis Phamaceuticals, Inc. |
Identification of novel drugs and reagents
|
US5427908A
(en)
*
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
US20060084797A1
(en)
*
|
1990-06-11 |
2006-04-20 |
Gilead Sciences, Inc. |
High affinity TGFbeta nucleic acid ligands and inhibitors
|
US5567588A
(en)
*
|
1990-06-11 |
1996-10-22 |
University Research Corporation |
Systematic evolution of ligands by exponential enrichment: Solution SELEX
|
US6140490A
(en)
*
|
1996-02-01 |
2000-10-31 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of complement system proteins
|
US5874218A
(en)
*
|
1990-06-11 |
1999-02-23 |
Nexstar Pharmaceuticals, Inc. |
Method for detecting a target compound in a substance using a nucleic acid ligand
|
US6083696A
(en)
*
|
1990-06-11 |
2000-07-04 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands exponential enrichment: blended selex
|
US5972599A
(en)
*
|
1990-06-11 |
1999-10-26 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of cytokines
|
US6610841B1
(en)
|
1997-12-18 |
2003-08-26 |
Gilead Sciences, Inc. |
Nucleotide-based prodrugs
|
US5731424A
(en)
*
|
1990-06-11 |
1998-03-24 |
Nexstar Pharmaceuticals, Inc. |
High affinity TGFβ nucleic acid ligands and inhibitors
|
US5789157A
(en)
*
|
1990-06-11 |
1998-08-04 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
US6569620B1
(en)
|
1990-06-11 |
2003-05-27 |
Somalogic, Inc. |
Method for the automated generation of nucleic acid ligands
|
US5270163A
(en)
*
|
1990-06-11 |
1993-12-14 |
University Research Corporation |
Methods for identifying nucleic acid ligands
|
US5683867A
(en)
*
|
1990-06-11 |
1997-11-04 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: blended SELEX
|
US5731144A
(en)
*
|
1990-06-11 |
1998-03-24 |
Nexstar Pharmaceuticals, Inc. |
High affinity TGFβ nucleic acid ligands
|
US5705337A
(en)
*
|
1990-06-11 |
1998-01-06 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chemi-SELEX
|
US6716580B2
(en)
|
1990-06-11 |
2004-04-06 |
Somalogic, Inc. |
Method for the automated generation of nucleic acid ligands
|
US5635615A
(en)
*
|
1990-06-11 |
1997-06-03 |
Nexstar Pharmaceuticals, Inc. |
High affinity HIV nucleocapsid nucleic acid ligands
|
US5543293A
(en)
*
|
1990-06-11 |
1996-08-06 |
Nexstar Pharmaceuticals, Inc. |
DNA ligands of thrombin
|
US6030776A
(en)
*
|
1990-06-11 |
2000-02-29 |
Nexstar Pharmaceuticals, Inc. |
Parallel SELEX
|
US6232071B1
(en)
*
|
1990-06-11 |
2001-05-15 |
Gilead Sciences, Inc. |
Tenascin-C nucleic acid ligands
|
US6395888B1
(en)
|
1996-02-01 |
2002-05-28 |
Gilead Sciences, Inc. |
High affinity nucleic acid ligands of complement system proteins
|
US6177557B1
(en)
|
1990-06-11 |
2001-01-23 |
Nexstar Pharmaceuticals, Inc. |
High affinity ligands of basic fibroblast growth factor and thrombin
|
US5763173A
(en)
*
|
1990-06-11 |
1998-06-09 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligand inhibitors to DNA polymerases
|
US5849890A
(en)
*
|
1990-06-11 |
1998-12-15 |
Nexstar Pharmaceuticals, Inc. |
High affinity oligonucleotide ligands to chorionic gonadotropin hormone and related glycoprotein hormones
|
US5641629A
(en)
*
|
1990-06-11 |
1997-06-24 |
Nexstar Pharmacueticals Inc |
Spectroscopically detectable nucleic acid ligands
|
US5503978A
(en)
*
|
1990-06-11 |
1996-04-02 |
University Research Corporation |
Method for identification of high affinity DNA ligands of HIV-1 reverse transcriptase
|
US6261774B1
(en)
*
|
1990-06-11 |
2001-07-17 |
Gilead Sciences, Inc. |
Truncation selex method
|
US5726017A
(en)
*
|
1990-06-11 |
1998-03-10 |
Nexstar Pharmaceuticals, Inc. |
High affinity HIV-1 gag nucleic acid ligands
|
US5846713A
(en)
*
|
1990-06-11 |
1998-12-08 |
Nexstar Pharmaceuticals, Inc. |
High affinity HKGF nucleic acid ligands and inhibitors
|
US6344321B1
(en)
|
1990-06-11 |
2002-02-05 |
Gilead Sciences, Inc. |
Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met
|
US5789163A
(en)
*
|
1990-06-11 |
1998-08-04 |
Nexstar Pharmaceuticals, Inc. |
Enzyme linked oligonucleotide assays (ELONAS)
|
US5780228A
(en)
*
|
1990-06-11 |
1998-07-14 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands to lectins
|
US5629155A
(en)
*
|
1990-06-11 |
1997-05-13 |
Nexstar Pharmaceuticals, Inc. |
High-affinity oligonucleotide ligands to immunoglobulin E (IgE)
|
US5648214A
(en)
*
|
1990-06-11 |
1997-07-15 |
University Research Corporation |
High-affinity oligonucleotide ligands to the tachykinin substance P
|
US6001577A
(en)
|
1998-06-08 |
1999-12-14 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
|
US5795721A
(en)
*
|
1990-06-11 |
1998-08-18 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of ICP4
|
US6465189B1
(en)
|
1990-06-11 |
2002-10-15 |
Gilead Sciences, Inc. |
Systematic evolution of ligands by exponential enrichment: blended selex
|
US6011020A
(en)
*
|
1990-06-11 |
2000-01-04 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligand complexes
|
US20040132067A1
(en)
*
|
1990-06-11 |
2004-07-08 |
Somalogic, Inc. |
Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
|
US5527894A
(en)
*
|
1990-06-11 |
1996-06-18 |
Nexstar Pharmacueticals, Inc. |
Ligands of HIV-1 tat protein
|
US6759392B1
(en)
|
1990-06-11 |
2004-07-06 |
Gilead Sciences, Inc. |
High affinity RNA ligands of basic fibroblast growth factor
|
US6001988A
(en)
*
|
1990-06-11 |
1999-12-14 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands to lectins
|
US5763177A
(en)
*
|
1990-06-11 |
1998-06-09 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
|
US5637459A
(en)
*
|
1990-06-11 |
1997-06-10 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chimeric selex
|
US5853984A
(en)
*
|
1990-06-11 |
1998-12-29 |
Nexstar Pharmaceuticals, Inc. |
Use of nucleic acid ligands in flow cytometry
|
US6331394B1
(en)
|
1991-06-10 |
2001-12-18 |
Gilead Sciences, Inc. |
Nucleic acid ligands to integrins
|
US5668264A
(en)
*
|
1990-06-11 |
1997-09-16 |
Nexstar Pharmaceuticals, Inc. |
High affinity PDGF nucleic acid ligands
|
US5837834A
(en)
*
|
1990-06-11 |
1998-11-17 |
Nexstar Pharmaceuticals, Inc. |
High affinity HKGF nucleic acid ligands and inhibitors
|
US5660985A
(en)
*
|
1990-06-11 |
1997-08-26 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands containing modified nucleotides
|
US5763566A
(en)
*
|
1990-06-11 |
1998-06-09 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue SELEX
|
US5587468A
(en)
*
|
1990-06-11 |
1996-12-24 |
University Research Corporation |
High affinity nucleic acid ligands to HIV integrase
|
US5756287A
(en)
*
|
1990-06-11 |
1998-05-26 |
Nexstar Pharmaceuticals, Inc. |
High affinity HIV integrase inhibitors
|
US5654151A
(en)
*
|
1990-06-11 |
1997-08-05 |
Nexstar Pharmaceuticals, Inc. |
High affinity HIV Nucleocapsid nucleic acid ligands
|
US5688935A
(en)
*
|
1990-06-11 |
1997-11-18 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands of tissue target
|
US5496938A
(en)
|
1990-06-11 |
1996-03-05 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands to HIV-RT and HIV-1 rev
|
US5962219A
(en)
*
|
1990-06-11 |
1999-10-05 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chemi-selex
|
US6465188B1
(en)
|
1990-06-11 |
2002-10-15 |
Gilead Sciences, Inc. |
Nucleic acid ligand complexes
|
US5712375A
(en)
*
|
1990-06-11 |
1998-01-27 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
US5861254A
(en)
*
|
1997-01-31 |
1999-01-19 |
Nexstar Pharmaceuticals, Inc. |
Flow cell SELEX
|
US5869641A
(en)
*
|
1990-06-11 |
1999-02-09 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of CD4
|
US6696252B2
(en)
|
1990-06-11 |
2004-02-24 |
Gilead Sciences, Inc. |
High-affinity oligonucleotide ligands to vascular endothelial growth factor (VEGF)
|
US5637682A
(en)
*
|
1990-06-11 |
1997-06-10 |
Nexstar Pharmaceuticals, Inc. |
High-affinity oligonucleotide ligands to the tachykinin substance P
|
US5723289A
(en)
*
|
1990-06-11 |
1998-03-03 |
Nexstar Pharmaceuticals, Inc. |
Parallel selex
|
US5459015A
(en)
*
|
1990-06-11 |
1995-10-17 |
Nexstar Pharmaceuticals, Inc. |
High-affinity RNA ligands of basic fibroblast growth factor
|
US5837456A
(en)
*
|
1990-06-11 |
1998-11-17 |
Nexstar Pharmaceuticals, Inc. |
High affinity oligonucleotide ligands to chorionic gonadotropin hormone and related glycoprotein hormones
|
US6124449A
(en)
*
|
1990-06-11 |
2000-09-26 |
Nexstar Pharmaceuticals, Inc. |
High affinity TGFβ nucleic acid ligands and inhibitors
|
US6280932B1
(en)
|
1990-06-11 |
2001-08-28 |
Gilead Sciences, Inc. |
High affinity nucleic acid ligands to lectins
|
ATE318832T1
(de)
*
|
1990-06-11 |
2006-03-15 |
Gilead Sciences Inc |
Verfahren zur vervendung von nukleinsäureliganden
|
US5472841A
(en)
*
|
1990-06-11 |
1995-12-05 |
Nexstar Pharmaceuticals, Inc. |
Methods for identifying nucleic acid ligands of human neutrophil elastase
|
US6346611B1
(en)
|
1990-06-11 |
2002-02-12 |
Gilead Sciences, Inc. |
High affinity TGfβ nucleic acid ligands and inhibitors
|
US5864026A
(en)
*
|
1990-06-11 |
1999-01-26 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
US5811533A
(en)
*
|
1990-06-11 |
1998-09-22 |
Nexstar Pharmaceuticals, Inc. |
High-affinity oligonucleotide ligands to vascular endothelial growth factor (VEGF)
|
US6127119A
(en)
*
|
1990-06-11 |
2000-10-03 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands of tissue target
|
US5750342A
(en)
*
|
1990-06-11 |
1998-05-12 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands of tissue target
|
US5707796A
(en)
*
|
1990-06-11 |
1998-01-13 |
Nexstar Pharmaceuticals, Inc. |
Method for selecting nucleic acids on the basis of structure
|
US5874557A
(en)
*
|
1990-06-11 |
1999-02-23 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligand inhibitors to DNA polymerases
|
US5674685A
(en)
*
|
1990-06-11 |
1997-10-07 |
Nexstar Pharmaceuticals, Inc. |
High affinity PDGF nucleic acid ligands
|
US5693502A
(en)
*
|
1990-06-11 |
1997-12-02 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligand inhibitors to DNA polymerases
|
US5766853A
(en)
*
|
1990-06-11 |
1998-06-16 |
Nexstar Pharmaceuticals, Inc. |
Method for identification of high affinity nucleic acid ligands to selectins
|
US5580737A
(en)
*
|
1990-06-11 |
1996-12-03 |
Nexstar Pharmaceuticals, Inc. |
High-affinity nucleic acid ligands that discriminate between theophylline and caffeine
|
US5686592A
(en)
*
|
1990-06-11 |
1997-11-11 |
Nexstar Pharmaceuticals, Inc. |
High-affinity oligonucleotide ligands to immunoglobulin E (IgE)
|
US5723286A
(en)
*
|
1990-06-20 |
1998-03-03 |
Affymax Technologies N.V. |
Peptide library and screening systems
|
GB9015198D0
(en)
*
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US6916605B1
(en)
|
1990-07-10 |
2005-07-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
US7063943B1
(en)
|
1990-07-10 |
2006-06-20 |
Cambridge Antibody Technology |
Methods for producing members of specific binding pairs
|
US5843701A
(en)
*
|
1990-08-02 |
1998-12-01 |
Nexstar Pharmaceticals, Inc. |
Systematic polypeptide evolution by reverse translation
|
WO1992015677A1
(en)
|
1991-03-01 |
1992-09-17 |
Protein Engineering Corporation |
Process for the development of binding mini-proteins
|
US6028186A
(en)
*
|
1991-06-10 |
2000-02-22 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of cytokines
|
US6762290B1
(en)
|
1999-07-29 |
2004-07-13 |
Gilead Sciences, Inc. |
High affinity vascular endothelial growth factor (VEGF) receptor nucleic acid ligands and inhibitors
|
AU2313392A
(en)
*
|
1991-08-01 |
1993-03-02 |
University Research Corporation |
Systematic polypeptide evolution by reverse translation
|
US5270170A
(en)
*
|
1991-10-16 |
1993-12-14 |
Affymax Technologies N.V. |
Peptide library and screening method
|
US5733731A
(en)
*
|
1991-10-16 |
1998-03-31 |
Affymax Technologies N.V. |
Peptide library and screening method
|
PT1024191E
(pt)
*
|
1991-12-02 |
2008-12-22 |
Medical Res Council |
Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
|
US5656467A
(en)
*
|
1992-01-09 |
1997-08-12 |
The Trustees Of The University Of Pennsylvania |
Methods and materials for producing gene libraries
|
EP0631620B1
(en)
*
|
1992-03-16 |
2004-10-20 |
WOHLSTADTER, Jacob Nathaniel |
Mutagenesis and selection methoden in the same host cells
|
US5869644A
(en)
*
|
1992-04-15 |
1999-02-09 |
The Johns Hopkins University |
Synthesis of diverse and useful collections of oligonucleotidies
|
US5719273A
(en)
*
|
1993-06-14 |
1998-02-17 |
Nexstar Pharmaceuticals, Inc. |
Palladium catalyzed nucleoside modifications methods using nucleophiles and carbon monoxide
|
US5998142A
(en)
*
|
1993-09-08 |
1999-12-07 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chemi-SELEX
|
US6458539B1
(en)
|
1993-09-17 |
2002-10-01 |
Somalogic, Inc. |
Photoselection of nucleic acid ligands
|
WO1995010296A1
(en)
*
|
1993-10-12 |
1995-04-20 |
Glycomed Incorporated |
A library of glyco-peptides useful for identification of cell adhesion inhibitors
|
DE69534347T2
(de)
|
1994-01-31 |
2006-05-24 |
Trustees Of Boston University, Boston |
Bibliotheken aus Polyklonalen Antikörpern
|
US20060078561A1
(en)
*
|
1994-01-31 |
2006-04-13 |
The Trustees Of Boston University |
Polyclonal antibody libraries
|
US6117679A
(en)
*
|
1994-02-17 |
2000-09-12 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US5837458A
(en)
|
1994-02-17 |
1998-11-17 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
US6395547B1
(en)
|
1994-02-17 |
2002-05-28 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US5605793A
(en)
|
1994-02-17 |
1997-02-25 |
Affymax Technologies N.V. |
Methods for in vitro recombination
|
US6165793A
(en)
*
|
1996-03-25 |
2000-12-26 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US6406855B1
(en)
|
1994-02-17 |
2002-06-18 |
Maxygen, Inc. |
Methods and compositions for polypeptide engineering
|
US6335160B1
(en)
*
|
1995-02-17 |
2002-01-01 |
Maxygen, Inc. |
Methods and compositions for polypeptide engineering
|
US6995017B1
(en)
|
1994-02-17 |
2006-02-07 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US6309883B1
(en)
|
1994-02-17 |
2001-10-30 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
US20060257890A1
(en)
*
|
1996-05-20 |
2006-11-16 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
US7153948B2
(en)
|
1994-04-25 |
2006-12-26 |
Gilead Sciences, Inc. |
High-affinity oligonucleotide ligands to vascular endothelial growth factor (VEGF)
|
US6682886B1
(en)
|
1994-04-28 |
2004-01-27 |
Gilead Sciences, Inc. |
Bivalent binding molecules of 7 transmembrane G protein-coupled receptors
|
US6010861A
(en)
*
|
1994-08-03 |
2000-01-04 |
Dgi Biotechnologies, Llc |
Target specific screens and their use for discovering small organic molecular pharmacophores
|
US6048698A
(en)
*
|
1994-09-20 |
2000-04-11 |
Nexstar Pharmaceuticals, Inc. |
Parallel SELEX™
|
ATE217344T1
(de)
*
|
1994-09-21 |
2002-05-15 |
Cytogen Corp |
Antigen bindende peptide (abtides) aus peptidbibliotheken
|
US5885577A
(en)
*
|
1994-09-21 |
1999-03-23 |
Cytogen Corporation |
Antigen binding peptides (abtides) from peptide libraries
|
US6013443A
(en)
*
|
1995-05-03 |
2000-01-11 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue SELEX
|
AU732961B2
(en)
*
|
1995-05-03 |
2001-05-03 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
US5859228A
(en)
*
|
1995-05-04 |
1999-01-12 |
Nexstar Pharmaceuticals, Inc. |
Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
|
US8071737B2
(en)
|
1995-05-04 |
2011-12-06 |
Glead Sciences, Inc. |
Nucleic acid ligand complexes
|
EP1741780A3
(en)
|
1995-06-02 |
2007-03-28 |
Gilead Sciences, Inc. |
High affinity oligonucleotide ligands to growth factors
|
US5723594A
(en)
*
|
1995-06-07 |
1998-03-03 |
Nexstar Pharmaceuticals, Inc. |
High affinity PDGF nucleic acid ligands
|
US20010053523A1
(en)
*
|
1995-06-02 |
2001-12-20 |
M&E Biotech A/S. |
Method for identification of biologically active peptides and nucleic acids
|
US6183967B1
(en)
|
1995-06-07 |
2001-02-06 |
Nexstar Pharmaceuticals |
Nucleic acid ligand inhibitors to DNA polymerases
|
US6699843B2
(en)
|
1995-06-07 |
2004-03-02 |
Gilead Sciences, Inc. |
Method for treatment of tumors using nucleic acid ligands to PDGF
|
US6229002B1
(en)
|
1995-06-07 |
2001-05-08 |
Nexstar Pharmaceuticlas, Inc. |
Platelet derived growth factor (PDGF) nucleic acid ligand complexes
|
US5797870A
(en)
*
|
1995-06-07 |
1998-08-25 |
Indiana University Foundation |
Pericardial delivery of therapeutic and diagnostic agents
|
US6475806B1
(en)
|
1995-06-07 |
2002-11-05 |
Praecis Pharmaceuticals, Inc. |
Anchor libraries and identification of peptide binding sequences
|
US6020130A
(en)
*
|
1995-06-07 |
2000-02-01 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands that bind to and inhibit DNA polymerases
|
US20090118481A1
(en)
*
|
1995-06-07 |
2009-05-07 |
Gilead Sciences, Inc. |
High Affinity Nucleic Acid Ligands To Lectins
|
US6358709B1
(en)
|
1995-12-07 |
2002-03-19 |
Diversa Corporation |
End selection in directed evolution
|
US20020164580A1
(en)
*
|
1995-12-07 |
2002-11-07 |
Diversa Corporation |
Combinatorial screening of mixed populations of organisms
|
US5830696A
(en)
|
1996-12-05 |
1998-11-03 |
Diversa Corporation |
Directed evolution of thermophilic enzymes
|
US6537776B1
(en)
*
|
1999-06-14 |
2003-03-25 |
Diversa Corporation |
Synthetic ligation reassembly in directed evolution
|
US7018793B1
(en)
*
|
1995-12-07 |
2006-03-28 |
Diversa Corporation |
Combinatorial screening of mixed populations of organisms
|
US6939689B2
(en)
|
1995-12-07 |
2005-09-06 |
Diversa Corporation |
Exonuclease-mediated nucleic acid reassembly in directed evolution
|
US6740506B2
(en)
|
1995-12-07 |
2004-05-25 |
Diversa Corporation |
End selection in directed evolution
|
US5965408A
(en)
|
1996-07-09 |
1999-10-12 |
Diversa Corporation |
Method of DNA reassembly by interrupting synthesis
|
US6361974B1
(en)
*
|
1995-12-07 |
2002-03-26 |
Diversa Corporation |
Exonuclease-mediated nucleic acid reassembly in directed evolution
|
US6352842B1
(en)
|
1995-12-07 |
2002-03-05 |
Diversa Corporation |
Exonucease-mediated gene assembly in directed evolution
|
US6713279B1
(en)
|
1995-12-07 |
2004-03-30 |
Diversa Corporation |
Non-stochastic generation of genetic vaccines and enzymes
|
US20030219752A1
(en)
*
|
1995-12-07 |
2003-11-27 |
Diversa Corporation |
Novel antigen binding molecules for therapeutic, diagnostic, prophylactic, enzymatic, industrial, and agricultural applications, and methods for generating and screening thereof
|
US20020028443A1
(en)
*
|
1999-09-27 |
2002-03-07 |
Jay M. Short |
Method of dna shuffling with polynucleotides produced by blocking or interrupting a synthesis or amplification process
|
US6365344B1
(en)
|
1996-01-23 |
2002-04-02 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for screening for transdominant effector peptides and RNA molecules
|
JP2000504220A
(ja)
*
|
1996-01-23 |
2000-04-11 |
ライガル ファーマシューティカルズ インコーポレイテッド |
トランス支配性細胞内作用因子ペプチドおよびrna分子のスクリーニング方法
|
US6506602B1
(en)
|
1996-03-25 |
2003-01-14 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US6096548A
(en)
|
1996-03-25 |
2000-08-01 |
Maxygen, Inc. |
Method for directing evolution of a virus
|
US6699658B1
(en)
|
1996-05-31 |
2004-03-02 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
US6300065B1
(en)
|
1996-05-31 |
2001-10-09 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
US6696251B1
(en)
|
1996-05-31 |
2004-02-24 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
US6838238B1
(en)
|
1996-10-17 |
2005-01-04 |
Invitrogen Corporation |
Morphatides: novel shape and structure libraries
|
US6426335B1
(en)
*
|
1997-10-17 |
2002-07-30 |
Gilead Sciences, Inc. |
Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
|
EP0948632A1
(en)
|
1996-10-31 |
1999-10-13 |
Smithkline Beecham Corporation |
Methods for the characterization and selection of rna target motifs that bind compounds of pharmaceutical use
|
US20070009930A1
(en)
*
|
1996-12-18 |
2007-01-11 |
Maxygen, Inc. |
Methods and compositions for polypeptide engineering
|
EP1007732B1
(en)
|
1997-01-17 |
2006-07-26 |
Maxygen, Inc. |
EVOLUTION OF procaryotic WHOLE CELLS BY RECURSIVE SEQUENCE RECOMBINATION
|
US7148054B2
(en)
|
1997-01-17 |
2006-12-12 |
Maxygen, Inc. |
Evolution of whole cells and organisms by recursive sequence recombination
|
US6326204B1
(en)
|
1997-01-17 |
2001-12-04 |
Maxygen, Inc. |
Evolution of whole cells and organisms by recursive sequence recombination
|
CA2278786C
(en)
|
1997-01-21 |
2010-07-20 |
The General Hospital Corporation |
Selection of proteins using rna-protein fusions
|
US8207093B2
(en)
*
|
1997-01-21 |
2012-06-26 |
The General Hospital Corporation |
Selection of proteins using RNA-protein fusions
|
US6261804B1
(en)
|
1997-01-21 |
2001-07-17 |
The General Hospital Corporation |
Selection of proteins using RNA-protein fusions
|
US5871924A
(en)
*
|
1997-01-27 |
1999-02-16 |
Nexstar Pharmaceuticals, Inc. |
Method for the production of ligands capable of facilitating aminoacyl-RNA synthesis
|
US6153410A
(en)
*
|
1997-03-25 |
2000-11-28 |
California Institute Of Technology |
Recombination of polynucleotide sequences using random or defined primers
|
US6180341B1
(en)
|
1997-05-01 |
2001-01-30 |
Board Of Regents, The Universiry Of Texas System |
In vitro scanning saturation mutagenesis of proteins
|
US7087420B1
(en)
|
1997-07-17 |
2006-08-08 |
Cambia |
Microbial β-glucuronidase genes, gene products and uses thereof
|
US6391547B1
(en)
*
|
1997-09-09 |
2002-05-21 |
Center For The Application Of Molecular Biology To International Agriculture |
Microbial β-glucuronidase genes, gene products and uses thereof
|
US6241701B1
(en)
|
1997-08-01 |
2001-06-05 |
Genetronics, Inc. |
Apparatus for electroporation mediated delivery of drugs and genes
|
US6670127B2
(en)
|
1997-09-16 |
2003-12-30 |
Egea Biosciences, Inc. |
Method for assembly of a polynucleotide encoding a target polypeptide
|
EP1690868A1
(en)
|
1997-10-31 |
2006-08-16 |
Maxygen, Inc. |
Modification of virus tropism and host range by viral genome shuffling
|
KR20010032861A
(ko)
|
1997-12-08 |
2001-04-25 |
캘리포니아 인스티튜트 오브 테크놀로지 |
폴리뉴클레오티드 및 폴리펩티드 서열을 형성하는 방법
|
US20070166741A1
(en)
|
1998-12-14 |
2007-07-19 |
Somalogic, Incorporated |
Multiplexed analyses of test samples
|
US20030219803A1
(en)
*
|
1997-12-15 |
2003-11-27 |
Somalogic, Incorporated |
Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
|
US5989823A
(en)
*
|
1998-09-18 |
1999-11-23 |
Nexstar Pharmaceuticals, Inc. |
Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
|
US6261783B1
(en)
|
1997-12-15 |
2001-07-17 |
Gilead Sciences, Inc. |
Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
|
US6759243B2
(en)
|
1998-01-20 |
2004-07-06 |
Board Of Trustees Of The University Of Illinois |
High affinity TCR proteins and methods
|
US6541011B2
(en)
|
1998-02-11 |
2003-04-01 |
Maxygen, Inc. |
Antigen library immunization
|
US7390619B1
(en)
*
|
1998-02-11 |
2008-06-24 |
Maxygen, Inc. |
Optimization of immunomodulatory properties of genetic vaccines
|
FR2782325B1
(fr)
|
1998-08-12 |
2002-05-24 |
Proteus |
Procede d'identification de sequences polynucleotidiques et/ou des proteines correspondantes a partir d'un echantillon d'acides nucleiques
|
US7157083B2
(en)
*
|
1998-04-17 |
2007-01-02 |
Surrogate Pharmaceutical Pathways, Llc |
Compositions and methods for treating retroviral infections
|
BR9910174A
(pt)
|
1998-05-01 |
2001-03-06 |
Maxygen Inc |
Processo para se obter um gene recombinante otimizado de resistência à praga, biblioteca, e, processo para se obter um organismo que seja patogênico a uma praga de vegetal
|
US7153655B2
(en)
|
1998-06-16 |
2006-12-26 |
Alligator Bioscience Ab |
Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence
|
US6365408B1
(en)
|
1998-06-19 |
2002-04-02 |
Maxygen, Inc. |
Methods of evolving a polynucleotides by mutagenesis and recombination
|
WO2000006717A2
(en)
|
1998-07-27 |
2000-02-10 |
Genentech, Inc. |
Improved transformation efficiency in phage display through modification of a coat protein
|
DE69941193D1
(de)
|
1998-08-17 |
2009-09-10 |
Bristol Myers Squibb Co |
Identifizierung von verbindung-protein wechselwirkungen mit bibliotheken von gekoppelten protein-nukleinsäure-molekülen
|
US6773911B1
(en)
*
|
1998-11-23 |
2004-08-10 |
Amgen Canada Inc. |
Apoptosis-inducing factor
|
US6570003B1
(en)
*
|
2001-01-09 |
2003-05-27 |
Lexion Genetics Incorporated |
Human 7TM proteins and polynucleotides encoding the same
|
JP2002537762A
(ja)
|
1999-01-05 |
2002-11-12 |
トラスティーズ オブ ボストン ユニバーシティ |
改良型核酸クローニング
|
US20030054390A1
(en)
*
|
1999-01-19 |
2003-03-20 |
Maxygen, Inc. |
Oligonucleotide mediated nucleic acid recombination
|
WO2000042559A1
(en)
*
|
1999-01-18 |
2000-07-20 |
Maxygen, Inc. |
Methods of populating data structures for use in evolutionary simulations
|
US20070065838A1
(en)
*
|
1999-01-19 |
2007-03-22 |
Maxygen, Inc. |
Oligonucleotide mediated nucleic acid recombination
|
US20030054360A1
(en)
*
|
1999-01-19 |
2003-03-20 |
Larry Gold |
Method and apparatus for the automated generation of nucleic acid ligands
|
US20090130718A1
(en)
*
|
1999-02-04 |
2009-05-21 |
Diversa Corporation |
Gene site saturation mutagenesis
|
US6329145B1
(en)
|
1999-02-09 |
2001-12-11 |
Gilead Science, Inc. |
Determining non-nucleic acid molecule binding to target by competition with nucleic acid ligand
|
CA2364997A1
(en)
|
1999-03-05 |
2000-09-08 |
Maxygen, Inc. |
Encryption of traits using split gene sequences
|
US6703240B1
(en)
|
1999-04-13 |
2004-03-09 |
Maxygar, Inc. |
Modified starch metabolism enzymes and encoding genes for improvement and optimization of plant phenotypes
|
US7332308B1
(en)
|
1999-05-21 |
2008-02-19 |
The Penn State Research Foundation |
Incrementally truncated nucleic acids and methods of making same
|
US6280943B1
(en)
|
1999-06-17 |
2001-08-28 |
Gilead Sciences, Inc. |
2′-fluoropyrimidine anti-calf intestinal phosphatase nucleic acid ligands
|
EP2241623A3
(en)
|
1999-07-07 |
2010-12-01 |
ZymoGenetics, Inc. |
Monoclonal antibody against a human cytokine receptor
|
US6387620B1
(en)
*
|
1999-07-28 |
2002-05-14 |
Gilead Sciences, Inc. |
Transcription-free selex
|
US6171795B1
(en)
|
1999-07-29 |
2001-01-09 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands to CD40ligand
|
US7005260B1
(en)
|
2000-01-28 |
2006-02-28 |
Gilead Sciences, Inc. |
Tenascin-C nucleic acid ligands
|
DE60042021D1
(de)
*
|
1999-07-29 |
2009-05-28 |
Gilead Sciences Inc |
Nukleinsäureliganden für den hepatozytischen wachstumsfaktor/dispersionsfaktor (hgf/sf) und seines c-met rezeptors
|
US6506887B1
(en)
|
1999-07-29 |
2003-01-14 |
Somalogic, Incorporated |
Conditional-selex
|
US20080050809A1
(en)
*
|
1999-09-28 |
2008-02-28 |
Alejandro Abuin |
Novel human kinases and polynucleotides encoding the same
|
US6586230B1
(en)
|
2000-10-27 |
2003-07-01 |
Lexicon Genetics Incorporated |
Human kinase and polynucleotides encoding the same
|
US6841377B1
(en)
|
2001-06-13 |
2005-01-11 |
Lexicon Genetics Incorporated |
Human kinase and polynucleotides encoding the same
|
US6541252B1
(en)
|
2000-05-19 |
2003-04-01 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
US6797510B1
(en)
*
|
2001-05-24 |
2004-09-28 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
US6759527B2
(en)
|
2001-03-20 |
2004-07-06 |
Lexicon Genetics Incorporated |
Human kinase and polynucleotides encoding the same
|
US6849425B1
(en)
|
1999-10-14 |
2005-02-01 |
Ixsys, Inc. |
Methods of optimizing antibody variable region binding affinity
|
JP2003516755A
(ja)
*
|
1999-12-15 |
2003-05-20 |
ジェネンテック・インコーポレーテッド |
ショットガン走査、すなわち機能性タンパク質エピトープをマッピングするための組み合わせ方法
|
US6489116B2
(en)
|
2000-01-24 |
2002-12-03 |
Phylos, Inc. |
Sensitive, multiplexed diagnostic assays for protein analysis
|
US7022479B2
(en)
*
|
2000-01-24 |
2006-04-04 |
Compound Therapeutics, Inc. |
Sensitive, multiplexed diagnostic assays for protein analysis
|
AU2001253117B8
(en)
*
|
2000-01-26 |
2006-08-03 |
Lexicon Pharmaceuticals, Inc. |
Human neurexin-like proteins and polynucleotides encoding the same
|
US20050239061A1
(en)
*
|
2000-03-01 |
2005-10-27 |
Marshall William S |
Identification and use of effectors and allosteric molecules for the alteration of gene expression
|
US7514239B2
(en)
|
2000-03-28 |
2009-04-07 |
Amgen Inc. |
Nucleic acid molecules encoding beta-like glycoprotein hormone polypeptides and heterodimers thereof
|
WO2001075178A2
(en)
*
|
2000-04-04 |
2001-10-11 |
Enanta Pharmaceuticals, Inc. |
Methods for identifying peptide aptamers capable of altering a cell phenotype
|
US8288322B2
(en)
|
2000-04-17 |
2012-10-16 |
Dyax Corp. |
Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
|
EP2295580A1
(en)
*
|
2000-04-17 |
2011-03-16 |
Dyax Corp. |
Methods of constructing display libraries of genetic packages for members of a diverse family of peptides
|
WO2001079562A1
(en)
*
|
2000-04-18 |
2001-10-25 |
Gilead Sciences, Inc. |
Aptamer based two-site binding assay
|
US6479262B1
(en)
|
2000-05-16 |
2002-11-12 |
Hercules, Incorporated |
Solid phase enzymatic assembly of polynucleotides
|
AU2001274923A1
(en)
*
|
2000-05-23 |
2001-12-03 |
Lexicon Genetics Incorporated |
Novel human thrombospondin-like proteins and polynucleotides encoding the same
|
AU2001275337A1
(en)
*
|
2000-06-07 |
2001-12-17 |
Lexicon Genetics Incorporated |
Novel human transporter proteins and polynucleotides encoding the same
|
US6465632B1
(en)
|
2000-06-09 |
2002-10-15 |
Lexicon Genetics Incorporated |
Human phosphatases and polynucleotides encoding the same
|
AU2001266844A1
(en)
*
|
2000-06-09 |
2001-12-17 |
Lexicon Genetics Incorporated |
Novel human seven transmembrane proteins and polynucleotides encoding the same
|
JP2004519205A
(ja)
|
2000-06-28 |
2004-07-02 |
アムジェン インコーポレイテッド |
胸腺間質リンホポイエチンレセプター分子およびその使用
|
US6994963B1
(en)
|
2000-07-10 |
2006-02-07 |
Ambion, Inc. |
Methods for recombinatorial nucleic acid synthesis
|
WO2002006456A1
(en)
*
|
2000-07-13 |
2002-01-24 |
Invitrogen Corporation |
Methods and compositions for rapid protein and peptide extraction and isolation using a lysis matrix
|
WO2002008408A2
(en)
*
|
2000-07-21 |
2002-01-31 |
Trustees Of Boston University |
Modular vector systems
|
WO2002010183A1
(en)
*
|
2000-07-31 |
2002-02-07 |
Menzel, Rolf |
Compositions and methods for directed gene assembly
|
US7288390B2
(en)
|
2000-08-07 |
2007-10-30 |
Centocor, Inc. |
Anti-dual integrin antibodies, compositions, methods and uses
|
US6902734B2
(en)
|
2000-08-07 |
2005-06-07 |
Centocor, Inc. |
Anti-IL-12 antibodies and compositions thereof
|
CA2417240A1
(en)
*
|
2000-08-07 |
2002-02-14 |
Sloan-Kettering Institute For Cancer Research |
Method and composition for immunization using mixed pools of mutated nucleic acids or peptides
|
UA81743C2
(uk)
|
2000-08-07 |
2008-02-11 |
Центокор, Инк. |
МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
|
AU2001286792A1
(en)
*
|
2000-08-22 |
2002-03-04 |
Lexicon Genetics Incorporated |
Novel human 7TM proteins and polynucleotides encoding the same
|
WO2002018555A2
(en)
*
|
2000-08-31 |
2002-03-07 |
Lexicon Genetics Incorporated |
Human kinase proteins and polynucleotides encoding the same
|
US6376190B1
(en)
|
2000-09-22 |
2002-04-23 |
Somalogic, Inc. |
Modified SELEX processes without purified protein
|
AU9630501A
(en)
*
|
2000-09-26 |
2002-04-08 |
Univ Duke |
Rna aptamers and methods for identifying the same
|
WO2002031745A1
(en)
*
|
2000-10-10 |
2002-04-18 |
Genencor International, Inc. |
Information rich libraries
|
AU2002224401B2
(en)
|
2000-10-16 |
2007-12-06 |
Gilead Sciences, Inc. |
Nucleic acid ligands to the prostate specific membrane antigen
|
JP2004533221A
(ja)
*
|
2000-10-27 |
2004-11-04 |
レキシコン・ジェネティクス・インコーポレーテッド |
新規ヒト7tmタンパクおよびそれをコードするポリヌクレオチド
|
JP2004531209A
(ja)
*
|
2000-10-30 |
2004-10-14 |
レキシコン・ジェネティクス・インコーポレーテッド |
新規ヒト7tmタンパクおよびそれをコードするポリヌクレオチド
|
AU2002228633A1
(en)
|
2000-11-20 |
2002-06-03 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
US20020165149A1
(en)
*
|
2000-12-08 |
2002-11-07 |
Kranz David M. |
Mutated class II major histocompatibility proteins
|
JP2004517622A
(ja)
*
|
2000-12-11 |
2004-06-17 |
レキシコン・ジェネティクス・インコーポレーテッド |
新規ヒトキナーゼ及び該キナーゼをコードするポリヌクレオチド
|
US6958213B2
(en)
|
2000-12-12 |
2005-10-25 |
Alligator Bioscience Ab |
Method for in vitro molecular evolution of protein function
|
CA2431210A1
(en)
*
|
2000-12-12 |
2002-06-20 |
Lexicon Genetics Incorporated |
Novel human kinases and uses thereof
|
ATE498718T1
(de)
*
|
2000-12-18 |
2011-03-15 |
Dyax Corp |
Gerichtete bibliotheken die genetisch verpackt sind
|
US6852844B1
(en)
*
|
2000-12-20 |
2005-02-08 |
Lexicon Genetics Incorporated |
Human protocadherin proteins and polynucleotides encoding the same
|
ES2390425T3
(es)
|
2000-12-22 |
2012-11-12 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Uso de moléculas de orientación repulsivas (RGM) y sus moduladores
|
US20020086292A1
(en)
|
2000-12-22 |
2002-07-04 |
Shigeaki Harayama |
Synthesis of hybrid polynucleotide molecules using single-stranded polynucleotide molecules
|
AU2002246858A1
(en)
*
|
2000-12-27 |
2002-08-06 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
JP4061043B2
(ja)
|
2000-12-28 |
2008-03-12 |
株式会社ポストゲノム研究所 |
invitro転写/翻訳系によるペプチド等の製造方法
|
US6849443B2
(en)
*
|
2001-01-23 |
2005-02-01 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
US7582423B2
(en)
*
|
2001-02-02 |
2009-09-01 |
Novici Biotech Llc |
Population of polynucleotide sequence variants
|
US7838219B2
(en)
*
|
2001-02-02 |
2010-11-23 |
Novici Biotech Llc |
Method of increasing complementarity in a heteroduplex
|
US20040142433A1
(en)
*
|
2001-02-02 |
2004-07-22 |
Padgett Hal S. |
Polynucleotide sequence variants
|
DE60234159D1
(de)
*
|
2001-02-02 |
2009-12-10 |
Large Scale Biology Corp |
Methode zur erhöhung der komplementarität in einem heteroduplex-polynucleotid
|
US20020127587A1
(en)
*
|
2001-02-13 |
2002-09-12 |
Domenica Simms |
Methods and compositions for isolation of biological macromolecules
|
US20030175685A1
(en)
*
|
2001-02-22 |
2003-09-18 |
Praecis Pharmaceuticals Inc. |
Methods for identifying peptides which modulate a biological process
|
WO2002070655A2
(en)
|
2001-03-02 |
2002-09-12 |
Zymogenetics, Inc. |
Mouse cytokine receptor
|
US7678554B2
(en)
|
2001-03-19 |
2010-03-16 |
President And Fellows Of Harvard College |
Nucleic acid shuffling
|
US7807408B2
(en)
*
|
2001-03-19 |
2010-10-05 |
President & Fellows Of Harvard College |
Directed evolution of proteins
|
CA2443319A1
(en)
|
2001-04-06 |
2002-10-17 |
Lexicon Genetics Incorporated |
Novel human kinase and polynucleotides encoding the same
|
JP2004524043A
(ja)
*
|
2001-04-06 |
2004-08-12 |
レキシコン・ジェネティクス・インコーポレーテッド |
新規ヒトキナーゼ及び該キナーゼをコードするポリヌクレオチド
|
US6644173B2
(en)
*
|
2001-04-11 |
2003-11-11 |
Keuring, Incorporated |
Beverage filter cartridge holder
|
AU2002254773B2
(en)
*
|
2001-05-03 |
2005-12-08 |
Rensselaer Polytechnic Institute |
Novel methods of directed evolution
|
EP1463749A4
(en)
*
|
2001-05-09 |
2005-04-13 |
Lexicon Genetics Inc |
NEW HUMAN KINASES AND THESE CODING POLYNUCLEOTIDES
|
WO2002097095A1
(en)
*
|
2001-05-25 |
2002-12-05 |
Lexicon Genetics Incorporated |
Novel human transporter proteins and polynucleotides encoding the same
|
ES2474192T3
(es)
*
|
2001-05-25 |
2014-07-08 |
Duke University |
Moduladores de agentes farmacol�gicos
|
EP1461425B1
(en)
|
2001-05-29 |
2008-02-13 |
Lexicon Pharmaceuticals, Inc. |
Novel human hydroxylases and polynucleotides encoding the same
|
US20030148380A1
(en)
*
|
2001-06-05 |
2003-08-07 |
Belcher Angela M. |
Molecular recognition of materials
|
US20070160576A1
(en)
|
2001-06-05 |
2007-07-12 |
Genentech, Inc. |
IL-17A/F heterologous polypeptides and therapeutic uses thereof
|
US20030113714A1
(en)
*
|
2001-09-28 |
2003-06-19 |
Belcher Angela M. |
Biological control of nanoparticles
|
US20050164515A9
(en)
*
|
2001-06-05 |
2005-07-28 |
Belcher Angela M. |
Biological control of nanoparticle nucleation, shape and crystal phase
|
KR100576674B1
(ko)
|
2001-06-20 |
2006-05-10 |
제넨테크, 인크. |
종양의 진단 및 치료를 위한 방법 및 이를 위한 조성물
|
DE10131441A1
(de)
*
|
2001-06-29 |
2003-01-30 |
Henkel Kgaa |
Eine neue Gruppe von alpha-Amylasen sowie ein Verfahren zur Identifizierung und Gewinnung neuer alpha-Amylasen
|
US20040204669A1
(en)
*
|
2001-07-05 |
2004-10-14 |
Hofmann Gunter A. |
Apparatus for electroporation mediated delivery for drugs and genes
|
EP1493028A4
(en)
*
|
2001-07-06 |
2006-06-14 |
Genentech Inc |
PHAGEN DISPLAY PRESENTED LIGANDS OF THE PDZ DOMAIN
|
US6943001B2
(en)
*
|
2001-08-03 |
2005-09-13 |
Diversa Corporation |
Epoxide hydrolases, nucleic acids encoding them and methods for making and using them
|
US6979733B2
(en)
*
|
2001-08-03 |
2005-12-27 |
Diversa Corporation |
Epoxide hydrolases, nucleic acids encoding them and methods of making and using them
|
DE10138753B4
(de)
*
|
2001-08-07 |
2017-07-20 |
Henkel Ag & Co. Kgaa |
Wasch- und Reinigungsmittel mit Hybrid-Alpha-Amylasen
|
US7647184B2
(en)
*
|
2001-08-27 |
2010-01-12 |
Hanall Pharmaceuticals, Co. Ltd |
High throughput directed evolution by rational mutagenesis
|
JP2005536439A
(ja)
|
2001-09-18 |
2005-12-02 |
ジェネンテック・インコーポレーテッド |
腫瘍の診断及び治療のための組成物と方法
|
DE60232672D1
(de)
|
2001-10-01 |
2009-07-30 |
Dyax Corp |
Mehrkettige eukaryontische display-vektoren und deren verwendungen
|
US20030073104A1
(en)
*
|
2001-10-02 |
2003-04-17 |
Belcher Angela M. |
Nanoscaling ordering of hybrid materials using genetically engineered mesoscale virus
|
EP1840211A1
(en)
|
2001-10-31 |
2007-10-03 |
Danisco A/S |
Pyranosone dehydratase from phanerochaete chrysosporium
|
US7291721B2
(en)
|
2001-11-14 |
2007-11-06 |
Centocor, Inc. |
Anti-IL-6 antibodies, compositions, methods and uses
|
EP1527341B1
(en)
*
|
2001-11-20 |
2009-06-17 |
Duke University |
Interfacial biomaterials
|
US6768476B2
(en)
*
|
2001-12-05 |
2004-07-27 |
Etenna Corporation |
Capacitively-loaded bent-wire monopole on an artificial magnetic conductor
|
WO2003051314A2
(en)
|
2001-12-18 |
2003-06-26 |
Medallion Biomedical, Llc |
Antibiotic compounds
|
US20030157534A1
(en)
*
|
2001-12-26 |
2003-08-21 |
Manuel Engelhorn |
DNA immunization with libraries of minigenes encoding degenerate variants of major histocompatability class l restricted epitopes
|
KR20080106369A
(ko)
|
2002-01-02 |
2008-12-04 |
제넨테크, 인크. |
종양의 진단 및 치료 방법 및 이를 위한 조성물
|
US20030224392A1
(en)
*
|
2002-01-28 |
2003-12-04 |
Manuel Engelhorn |
Method for identification of mutant antigens with enhanced immunogenicity
|
US20030157495A1
(en)
*
|
2002-02-01 |
2003-08-21 |
Padgett Hal S. |
Nucleic acid molecules encoding CEL I endonuclease and methods of use thereof
|
US7078211B2
(en)
*
|
2002-02-01 |
2006-07-18 |
Large Scale Biology Corporation |
Nucleic acid molecules encoding endonucleases and methods of use thereof
|
AU2003217379A1
(en)
|
2002-02-15 |
2003-09-09 |
Somalogic, Inc. |
Methods and reagents for detecting target binding by nucleic acid ligands
|
AU2003217693A1
(en)
*
|
2002-02-22 |
2003-09-09 |
Board Of Trustees Of The University Of Illinois |
Beta chain-associated regulator of apoptosis
|
US7662924B2
(en)
*
|
2002-02-22 |
2010-02-16 |
The Board Of Trustees Of The University Of Illinois |
Beta chain-associated regulator of apoptosis
|
US20030166010A1
(en)
*
|
2002-02-25 |
2003-09-04 |
Affholter Joseph A. |
Custom ligand design for biomolecular filtration and purification for bioseperation
|
US20030224404A1
(en)
*
|
2002-02-25 |
2003-12-04 |
Manuel Vega |
High throughput directed evolution of nucleic acids by rational mutagenesis
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
JP2005536190A
(ja)
|
2002-04-16 |
2005-12-02 |
ジェネンテック・インコーポレーテッド |
腫瘍の診断と治療のための組成物と方法
|
CN1659276A
(zh)
|
2002-04-19 |
2005-08-24 |
戴弗萨公司 |
磷脂酶,编码磷脂酶的核酸以及制备和应用磷脂酶的方法
|
US7226771B2
(en)
|
2002-04-19 |
2007-06-05 |
Diversa Corporation |
Phospholipases, nucleic acids encoding them and methods for making and using them
|
DK1504098T4
(da)
|
2002-05-17 |
2011-05-23 |
Alligator Bioscience Ab |
Fremgangsmåde til molekyulær udvikling in vitro af proteinfunktion
|
JP4753578B2
(ja)
*
|
2002-06-03 |
2011-08-24 |
ジェネンテック, インコーポレイテッド |
合成抗体ファージライブラリー
|
US20030232395A1
(en)
*
|
2002-06-14 |
2003-12-18 |
Dyax Corporation |
Recombination of nucleic acid library members
|
US20040022727A1
(en)
*
|
2002-06-18 |
2004-02-05 |
Martin Stanton |
Aptamer-toxin molecules and methods for using same
|
EP1543158B1
(en)
|
2002-07-25 |
2011-07-13 |
Archemix Corp. |
Regulated aptamer therapeutics
|
MXPA05001287A
(es)
|
2002-08-06 |
2005-08-03 |
Verdia Llc |
Variantes de amino oxidasa ap1.
|
US20040067532A1
(en)
|
2002-08-12 |
2004-04-08 |
Genetastix Corporation |
High throughput generation and affinity maturation of humanized antibody
|
US20060020396A1
(en)
*
|
2002-09-09 |
2006-01-26 |
Rene Gantier |
Rational directed protein evolution using two-dimensional rational mutagenesis scanning
|
US20050202438A1
(en)
*
|
2002-09-09 |
2005-09-15 |
Rene Gantier |
Rational directed protein evolution using two-dimensional rational mutagenesis scanning
|
CA2498319A1
(en)
*
|
2002-09-09 |
2004-03-18 |
Nautilus Biotech |
Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
|
US9303262B2
(en)
|
2002-09-17 |
2016-04-05 |
Archemix Llc |
Methods for identifying aptamer regulators
|
US20050064508A1
(en)
*
|
2003-09-22 |
2005-03-24 |
Semzyme |
Peptide mediated synthesis of metallic and magnetic materials
|
AU2003279719B8
(en)
|
2002-09-27 |
2009-01-08 |
Xencor Inc. |
Optimized Fc variants and methods for their generation
|
JP3447009B1
(ja)
*
|
2002-10-29 |
2003-09-16 |
實 平垣 |
構築物用構成体およびその製造方法
|
EP1581548A4
(en)
*
|
2002-11-21 |
2008-04-23 |
Archemix Corp |
MULTIVALENT APTAMER THERAPEUTIC WITH IMPROVED PHARMACODYNAMIC PROPERTIES AND METHOD FOR THE PRODUCTION AND USE THEREOF
|
US20050124565A1
(en)
*
|
2002-11-21 |
2005-06-09 |
Diener John L. |
Stabilized aptamers to platelet derived growth factor and their use as oncology therapeutics
|
US10100316B2
(en)
|
2002-11-21 |
2018-10-16 |
Archemix Llc |
Aptamers comprising CPG motifs
|
US8853376B2
(en)
|
2002-11-21 |
2014-10-07 |
Archemix Llc |
Stabilized aptamers to platelet derived growth factor and their use as oncology therapeutics
|
US20040197804A1
(en)
*
|
2002-12-03 |
2004-10-07 |
Keefe Anthony D. |
Method for in vitro selection of 2'-substituted nucleic acids
|
US20050037394A1
(en)
*
|
2002-12-03 |
2005-02-17 |
Keefe Anthony D. |
Method for in vitro selection of 2'-substituted nucleic acids
|
JP2006523435A
(ja)
*
|
2002-12-26 |
2006-10-19 |
アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ |
Lgr6のスプライス変異
|
US20050079574A1
(en)
*
|
2003-01-16 |
2005-04-14 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
PL3023498T3
(pl)
|
2003-03-06 |
2019-05-31 |
Basf Enzymes Llc |
Amylazy, kodujące je kwasy nukleinowe i sposoby ich wytwarzania i zastosowania
|
WO2005032496A2
(en)
|
2003-03-07 |
2005-04-14 |
Diversa Corporation |
Hydrolases, nucleic acids encoding them and mehods for making and using them
|
DK1613733T3
(en)
|
2003-04-04 |
2015-08-31 |
Basf Enzymes Llc |
PEKTATLYASER, nucleic acids encoding them, and methods for making and using the
|
US20050250106A1
(en)
*
|
2003-04-24 |
2005-11-10 |
David Epstein |
Gene knock-down by intracellular expression of aptamers
|
WO2004106488A2
(en)
*
|
2003-05-12 |
2004-12-09 |
Potomac Pharmaceuticals, Inc. |
Gene expression suppression agents
|
US9708410B2
(en)
|
2003-05-30 |
2017-07-18 |
Janssen Biotech, Inc. |
Anti-tissue factor antibodies and compositions
|
EP2404929B1
(en)
|
2003-07-02 |
2014-06-18 |
BP Corporation North America Inc. |
Glucanases, nucleic acids encoding them and methods for making and using them
|
ES2424353T3
(es)
|
2003-07-08 |
2013-10-01 |
Genentech, Inc. |
Polipéptidos heterólogos IL-17 A/F y usos terapéuticos de los mismos
|
WO2005012531A2
(en)
*
|
2003-08-01 |
2005-02-10 |
Genentech, Inc. |
Antibody cdr polypeptide sequences with restricted diversity
|
EP2311994A1
(en)
*
|
2003-08-01 |
2011-04-20 |
Life Technologies Corporation |
Compositions and methods for preparing short RNA molecules and other nucleic acids
|
EP1668113B1
(en)
|
2003-08-11 |
2013-06-19 |
Verenium Corporation |
Laccases, nucleic acids encoding them and methods for making and using them
|
JP2005065575A
(ja)
*
|
2003-08-22 |
2005-03-17 |
Japan Science & Technology Agency |
フレームシャッフリングによるタンパク質分子多様性集団の作製
|
US20050042664A1
(en)
*
|
2003-08-22 |
2005-02-24 |
Medimmune, Inc. |
Humanization of antibodies
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
US20060134105A1
(en)
*
|
2004-10-21 |
2006-06-22 |
Xencor, Inc. |
IgG immunoglobulin variants with optimized effector function
|
US8883147B2
(en)
|
2004-10-21 |
2014-11-11 |
Xencor, Inc. |
Immunoglobulins insertions, deletions, and substitutions
|
SI2161283T1
(sl)
|
2003-11-17 |
2014-10-30 |
Genentech, Inc. |
Sestavki, ki obsegajo protitelesa proti CD79b, konjugirana na sredstvo, ki inhibira rast, ali na citotoksično sredstvo, in postopki za zdravljenje tumorja hematopoetskega izvora
|
US20050112585A1
(en)
*
|
2003-11-21 |
2005-05-26 |
Dominic Zichi |
Method for adjusting the quantification range of individual analytes in a multiplexed assay
|
EP1697741A4
(en)
*
|
2003-12-04 |
2008-02-13 |
Xencor Inc |
PROCESS FOR PRODUCING PROTEIN VARIANTS WITH INCREASED HOST STRUCTURE CONTENT AND COMPOSITIONS THEREOF
|
CA2550431A1
(en)
*
|
2003-12-19 |
2005-07-14 |
Osteotech, Inc. |
Tissue-derived mesh for orthopedic regeneration
|
DK1727567T3
(da)
|
2004-02-12 |
2013-10-14 |
Archemix Llc |
Aptamer-terapeutiske midler nyttige i behandling af komplementrelaterede forstyrrelser
|
US7803931B2
(en)
|
2004-02-12 |
2010-09-28 |
Archemix Corp. |
Aptamer therapeutics useful in the treatment of complement-related disorders
|
MXPA06010012A
(es)
*
|
2004-03-05 |
2007-03-23 |
Archemix Corp |
Aptameros de la familia citocina il-12 humana y su uso en la terapeutica de enfermedad autoinmune.
|
US20060193821A1
(en)
*
|
2004-03-05 |
2006-08-31 |
Diener John L |
Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics
|
US7569223B2
(en)
*
|
2004-03-22 |
2009-08-04 |
The Rockefeller University |
Phage-associated lytic enzymes for treatment of Streptococcus pneumoniae and related conditions
|
US7276585B2
(en)
|
2004-03-24 |
2007-10-02 |
Xencor, Inc. |
Immunoglobulin variants outside the Fc region
|
US7785903B2
(en)
*
|
2004-04-09 |
2010-08-31 |
Genentech, Inc. |
Variable domain library and uses
|
US20080214489A1
(en)
*
|
2004-04-19 |
2008-09-04 |
Anthony Dominic Keefe |
Aptamer-mediated intracellular delivery of oligonucleotides
|
EP1745062B1
(en)
*
|
2004-04-22 |
2014-06-04 |
Regado Biosciences, Inc. |
Improved modulators of coagulation factors
|
US7579450B2
(en)
|
2004-04-26 |
2009-08-25 |
Archemix Corp. |
Nucleic acid ligands specific to immunoglobulin E and their use as atopic disease therapeutics
|
EP1745292A2
(en)
|
2004-04-28 |
2007-01-24 |
Bayer HealthCare AG |
Diagnostics and therapeutics for diseases associated with dipeptidyl-peptidase 1 (dpp1)
|
EP1789453A2
(en)
*
|
2004-05-18 |
2007-05-30 |
Genentech, Inc. |
M13 virus major coat protein variants for c-terminal and bi-terminal display of a heterologous protein
|
CN103173282A
(zh)
|
2004-06-16 |
2013-06-26 |
帝斯曼知识产权资产管理有限公司 |
对叶绿素进行酶促脱色的组合物和方法
|
EP1791557A4
(en)
|
2004-09-07 |
2009-09-23 |
Archemix Corp |
MEDICAL CHEMISTRY USING APTAMERS
|
KR20070101227A
(ko)
|
2004-09-07 |
2007-10-16 |
아케믹스 코포레이션 |
폰 빌레브란트 인자에 대한 앱타머 및 이의 혈전증치료제로서의 용도
|
US7566701B2
(en)
|
2004-09-07 |
2009-07-28 |
Archemix Corp. |
Aptamers to von Willebrand Factor and their use as thrombotic disease therapeutics
|
GB0422052D0
(en)
|
2004-10-04 |
2004-11-03 |
Dansico As |
Enzymes
|
GB0423139D0
(en)
|
2004-10-18 |
2004-11-17 |
Danisco |
Enzymes
|
KR101027427B1
(ko)
|
2004-11-12 |
2011-04-11 |
젠코어 인코포레이티드 |
FcRn에 대하여 증가된 결합력을 갖는 Fc 변이체
|
CA2594356C
(en)
|
2005-01-05 |
2018-07-17 |
F-Star Biotechnologische Forschungs- Und Entwicklungsges.M.B.H. |
Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
|
PA8660701A1
(es)
|
2005-02-04 |
2006-09-22 |
Pfizer Prod Inc |
Agonistas de pyy y sus usos
|
EP2192132A3
(en)
|
2005-02-08 |
2010-08-18 |
ZymoGenetics, Inc. |
Anti-IL-20, anti-IL22 and anti-IL-22RA antibodies and binding partners and methods of using in inflammation
|
CA2597325A1
(en)
|
2005-03-10 |
2006-09-21 |
Genentech, Inc. |
Methods and compositions for modulating vascular integrity
|
CA2614769A1
(en)
|
2005-03-10 |
2006-09-21 |
Verenium Corporation |
Lyase enzymes, nucleic acids encoding them and methods for making and using them
|
EA013540B1
(ru)
|
2005-03-15 |
2010-06-30 |
Верениум Корпорейшн |
Целлюлазы, нуклеиновые кислоты, кодирующие их, и способы их получения и применения
|
JO3058B1
(ar)
|
2005-04-29 |
2017-03-15 |
Applied Molecular Evolution Inc |
الاجسام المضادة لمضادات -اي ال-6,تركيباتها طرقها واستعمالاتها
|
AU2006247591B2
(en)
|
2005-05-12 |
2011-12-15 |
Zymogenetics, Inc. |
Compositions and methods for modulating immune responses
|
US20060271262A1
(en)
*
|
2005-05-24 |
2006-11-30 |
Mclain Harry P Iii |
Wireless agricultural network
|
US8389469B2
(en)
*
|
2005-06-06 |
2013-03-05 |
The Rockefeller University |
Bacteriophage lysins for Bacillus anthracis
|
US7582291B2
(en)
*
|
2005-06-30 |
2009-09-01 |
The Rockefeller University |
Bacteriophage lysins for Enterococcus faecalis, Enterococcus faecium and other bacteria
|
CN103146708A
(zh)
*
|
2005-06-30 |
2013-06-12 |
Abbvie公司 |
Il-12/p40结合蛋白
|
HUE042561T2
(hu)
|
2005-06-30 |
2019-07-29 |
Janssen Biotech Inc |
Anti-IL-23-ellenanyagok, készítmények, eljárások és alkalmazások
|
EP2520588A1
(en)
|
2005-08-19 |
2012-11-07 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
EP2500356A3
(en)
|
2005-08-19 |
2012-10-24 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
US20090215992A1
(en)
*
|
2005-08-19 |
2009-08-27 |
Chengbin Wu |
Dual variable domain immunoglobulin and uses thereof
|
CN101297034A
(zh)
*
|
2005-08-24 |
2008-10-29 |
洛克菲勒大学 |
Ply-gbs突变溶素
|
WO2007035527A2
(en)
|
2005-09-15 |
2007-03-29 |
Duke University |
Non-fouling polymeric surface modification and signal amplification method for biomolecular detection
|
CN101277974A
(zh)
*
|
2005-09-30 |
2008-10-01 |
阿伯特有限及两合公司 |
排斥性引导分子(rgm)蛋白质家族的蛋白质的结合结构域及其功能性片段和它们的用途
|
US8679490B2
(en)
|
2005-11-07 |
2014-03-25 |
Genentech, Inc. |
Binding polypeptides with diversified and consensus VH/VL hypervariable sequences
|
GB2432366B
(en)
*
|
2005-11-19 |
2007-11-21 |
Alligator Bioscience Ab |
A method for in vitro molecular evolution of protein function
|
IL297746A
(en)
*
|
2005-11-30 |
2022-12-01 |
Abbvie Inc |
Monoclonal antibodies against amyloid beta protein and uses thereof
|
PL1954718T3
(pl)
|
2005-11-30 |
2015-04-30 |
Abbvie Inc |
Przeciwciała skierowane przeciwko A globulomerowi, ich reszty wiążące antygeny, odpowiednie hybrydomy, kwasy nukleinowe, wektory, komórki gospodarze, sposoby wytwarzania tych przeciwciał, kompozycje zawierające te przeciwciała, zastosowania tych przeciwciał i sposoby stosowania tych przeciwciał
|
WO2007064919A2
(en)
*
|
2005-12-02 |
2007-06-07 |
Genentech, Inc. |
Binding polypeptides with restricted diversity sequences
|
UA101301C2
(ru)
|
2005-12-29 |
2013-03-25 |
Сентокор, Инк. |
ВЫДЕЛЕННОЕ АНТИТЕЛО ПРОТИВ IL-23pl 9 И ЕГО ПРИМЕНЕНИЕ
|
WO2007092314A2
(en)
|
2006-02-02 |
2007-08-16 |
Verenium Corporation |
Esterases and related nucleic acids and methods
|
WO2007092313A2
(en)
*
|
2006-02-03 |
2007-08-16 |
Indiana University Research And Technology Corporation |
Construction of open reading frame libraries and protein structures
|
NZ595499A
(en)
|
2006-02-10 |
2013-05-31 |
Verenium Corp |
Cellulolytic enzymes, nucleic acids encoding them and methods for making and using them
|
EP2548954A1
(en)
|
2006-02-14 |
2013-01-23 |
Verenium Corporation |
Xylanases, nucleic acids encoding them and methods for making and using them
|
ES2416104T3
(es)
|
2006-03-07 |
2013-07-30 |
Cargill, Incorporated |
Aldolasas, ácidos nucleicos que las codifican y métodos para producir y usar las mismas
|
EA029538B1
(ru)
|
2006-03-07 |
2018-04-30 |
Басф Энзаймс Ллк |
Полипептид, обладающий активностью альдолазы, полинуклеотид, кодирующий этот полипептид, и способы получения и применения полинуклеотида и полипептида
|
PT2596807E
(pt)
*
|
2006-03-08 |
2016-03-18 |
Archemix Llc |
Aptâmeros de ligação ao complemento e agentes anti-c5 úteis no tratamento de distúrbios oculares
|
CA2647277A1
(en)
|
2006-04-05 |
2007-11-08 |
Genentech, Inc. |
Method for using boc/cdo to modulate hedgehog signaling
|
AR060871A1
(es)
*
|
2006-05-09 |
2008-07-16 |
Genentech Inc |
Union de polipeptidos con supercontigos optimizados
|
AT503889B1
(de)
*
|
2006-07-05 |
2011-12-15 |
Star Biotechnologische Forschungs Und Entwicklungsges M B H F |
Multivalente immunglobuline
|
AT503902B1
(de)
|
2006-07-05 |
2008-06-15 |
F Star Biotech Forsch & Entw |
Verfahren zur manipulation von immunglobulinen
|
AT503861B1
(de)
*
|
2006-07-05 |
2008-06-15 |
F Star Biotech Forsch & Entw |
Verfahren zur manipulation von t-zell-rezeptoren
|
WO2008012629A2
(en)
|
2006-07-24 |
2008-01-31 |
Biorexis Pharmaceutical Corporation |
Exendin fusion proteins
|
CN103397043A
(zh)
|
2006-08-04 |
2013-11-20 |
维莱尼姆公司 |
葡聚糖酶、编码它们的核酸及制备和使用它们的方法
|
EP2520935A3
(en)
|
2006-08-09 |
2013-02-13 |
Homestead Clinical Corporation |
Organ-specific proteins and methods of their use
|
MX349810B
(es)
*
|
2006-09-08 |
2017-08-14 |
Abbvie Bahamas Ltd |
Proteinas de enlace de interleucina-13.
|
WO2008032833A1
(fr)
|
2006-09-14 |
2008-03-20 |
Medical & Biological Laboratories Co., Ltd. |
Anticorps présentant une activité adcc accrue et son procédé de production
|
EP2617820B1
(en)
|
2006-09-21 |
2016-03-23 |
BASF Enzymes LLC |
Phytases, nucleic acids encoding them and methods for making and using them
|
US8637290B2
(en)
|
2006-09-21 |
2014-01-28 |
Dsm Ip Assets B.V. |
Phospholipases, nucleic acids encoding them and methods for making and using them
|
US9382327B2
(en)
|
2006-10-10 |
2016-07-05 |
Vaccinex, Inc. |
Anti-CD20 antibodies and methods of use
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
DK2479267T3
(en)
|
2006-12-21 |
2017-03-27 |
Basf Enzymes Llc |
Amylases and Glucoamylases, Nucleic Acids Encoding Them, and Methods for Preparing and Using Them
|
US7947447B2
(en)
|
2007-01-16 |
2011-05-24 |
Somalogic, Inc. |
Method for generating aptamers with improved off-rates
|
US7855054B2
(en)
|
2007-01-16 |
2010-12-21 |
Somalogic, Inc. |
Multiplexed analyses of test samples
|
US20110136099A1
(en)
|
2007-01-16 |
2011-06-09 |
Somalogic, Inc. |
Multiplexed Analyses of Test Samples
|
US7964356B2
(en)
|
2007-01-16 |
2011-06-21 |
Somalogic, Inc. |
Method for generating aptamers with improved off-rates
|
US8975026B2
(en)
|
2007-01-16 |
2015-03-10 |
Somalogic, Inc. |
Method for generating aptamers with improved off-rates
|
AU2008205457A1
(en)
*
|
2007-01-18 |
2008-07-24 |
University Of Southern California |
Gene polymorphisms predictive for dual TKI therapy
|
US20100189706A1
(en)
|
2007-01-30 |
2010-07-29 |
Cathy Chang |
Enzymes for the treatment of lignocellulosics, nucleic acids encoding them and methods for making and using them
|
US8143046B2
(en)
|
2007-02-07 |
2012-03-27 |
Danisco Us Inc., Genencor Division |
Variant Buttiauxella sp. phytases having altered properties
|
JP2010520748A
(ja)
|
2007-02-20 |
2010-06-17 |
アナプティスバイオ インコーポレイティッド |
体細胞超変異系
|
ATE541059T1
(de)
|
2007-02-22 |
2012-01-15 |
Genentech Inc |
Verfahren für den nachweis von entzündlicher darmerkrankung
|
EP2486928A1
(en)
*
|
2007-02-27 |
2012-08-15 |
Abbott GmbH & Co. KG |
Method for the treatment of amyloidoses
|
US20090232801A1
(en)
*
|
2007-05-30 |
2009-09-17 |
Abbot Laboratories |
Humanized Antibodies Which Bind To AB (1-42) Globulomer And Uses Thereof
|
US20090175847A1
(en)
*
|
2007-05-30 |
2009-07-09 |
Abbott Laboratories |
Humanized antibodies to ab (20-42) globulomer and uses thereof
|
WO2008150495A2
(en)
*
|
2007-06-01 |
2008-12-11 |
Archemix Corp. |
Vwf aptamer formulations and methods for use
|
US8921279B2
(en)
|
2007-06-26 |
2014-12-30 |
F-Star Biotechnologische Forschungs—und Entwicklungsges. m.b.H |
Display of binding agents
|
CA2693448A1
(en)
|
2007-07-17 |
2009-01-22 |
Somalogic, Inc. |
Improved selex and photoselex
|
EP2033971A1
(de)
*
|
2007-09-06 |
2009-03-11 |
Abbott GmbH & Co. KG |
Bone Morphogenetic Protein (BMP)-bindende Domänen von Proteinen der Repulsive Guidance Molecule (RGM) Proteinfamilie und funktionale Fragmente davon sowie deren Verwendung
|
DK3124497T3
(da)
*
|
2007-09-14 |
2020-05-11 |
Adimab Llc |
Rationelt designede syntetiske antistofbiblioteker og anvendelser deraf
|
US8877688B2
(en)
*
|
2007-09-14 |
2014-11-04 |
Adimab, Llc |
Rationally designed, synthetic antibody libraries and uses therefor
|
CN102533702A
(zh)
|
2007-09-28 |
2012-07-04 |
普托拉制药有限公司 |
用于因子xa抑制剂的解毒剂和其使用方法
|
EP2708602B1
(en)
|
2007-10-03 |
2019-02-27 |
BP Corporation North America Inc. |
Xylanases, nucleic acids encoding them and methods for making and using them
|
WO2009055005A2
(en)
|
2007-10-23 |
2009-04-30 |
The Regents Of The University Of Colorado |
Competitive inhibitors of invariant chain expression and/or ectopic clip binding
|
WO2009055656A2
(en)
|
2007-10-26 |
2009-04-30 |
Centocor, Inc. |
Vectors, host cells, and methods of production and uses
|
US8906700B2
(en)
|
2007-11-06 |
2014-12-09 |
Ambergen, Inc. |
Methods and compositions for phototransfer
|
WO2009088924A2
(en)
*
|
2007-12-31 |
2009-07-16 |
Xoma Technology Ltd. |
Methods and materials for targeted affinity enhancement
|
US8541220B2
(en)
|
2008-01-03 |
2013-09-24 |
Verenium Corporation |
Isomerases, nucleic acids encoding them and methods for making and using them
|
CN104651381A
(zh)
|
2008-01-03 |
2015-05-27 |
巴斯夫酶有限责任公司 |
转移酶和氧化还原酶、编码它们的核酸以及其制备和应用方法
|
US7682809B2
(en)
|
2008-01-11 |
2010-03-23 |
Agilent Technologies, Inc. |
Direct ATP release sequencing
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
US9873957B2
(en)
*
|
2008-03-13 |
2018-01-23 |
Dyax Corp. |
Libraries of genetic packages comprising novel HC CDR3 designs
|
CA3049612C
(en)
*
|
2008-04-24 |
2023-01-10 |
Dyax Corp. |
Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs
|
MX2010011955A
(es)
|
2008-04-29 |
2011-01-21 |
Abbott Lab |
Inmunoglobulinas de dominio variable doble y usos de las mismas.
|
US20100260668A1
(en)
*
|
2008-04-29 |
2010-10-14 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
WO2009133462A2
(en)
|
2008-04-30 |
2009-11-05 |
Danisco A/S |
Proteins
|
EP2113255A1
(en)
|
2008-05-02 |
2009-11-04 |
f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. |
Cytotoxic immunoglobulin
|
KR101603917B1
(ko)
|
2008-05-09 |
2016-03-17 |
애브비 인코포레이티드 |
최종 당화 산물의 수용체(rage)에 대한 항체 및 이의 용도
|
CA2725666A1
(en)
*
|
2008-06-03 |
2009-12-10 |
Abbott Laboratories |
Dual variable domain immunoglobulins and uses thereof
|
CN102112495A
(zh)
*
|
2008-06-03 |
2011-06-29 |
雅培制药有限公司 |
双重可变结构域免疫球蛋白及其用途
|
KR20110038047A
(ko)
|
2008-06-20 |
2011-04-13 |
고꾸리츠 다이가꾸 호우징 오까야마 다이가꾸 |
산화 LDL/β2GPI복합체에 대한 항체 및 그 용도
|
EP2303318A2
(en)
|
2008-06-20 |
2011-04-06 |
Wyeth LLC |
Compositions and methods of use of orf1358 from beta-hemolytic streptococcal strains
|
SG192489A1
(en)
*
|
2008-07-08 |
2013-08-30 |
Abbott Lab |
Prostaglandin e2 dual variable domain immunoglobulins and uses thereof
|
WO2010006059A1
(en)
|
2008-07-08 |
2010-01-14 |
Abbott Laboratories |
Prostaglandin e2 binding proteins and uses thereof
|
US8703416B2
(en)
|
2008-07-17 |
2014-04-22 |
Somalogic, Inc. |
Method for purification and identification of sperm cells
|
CA2736842A1
(en)
*
|
2008-07-25 |
2010-01-28 |
The Regents Of The University Of Colorado |
Proteins for use in diagnosing and treating infection and disease
|
US20100166782A1
(en)
*
|
2008-07-25 |
2010-07-01 |
Martha Karen Newell |
Clip inhibitors and methods of modulating immune function
|
US9182406B2
(en)
*
|
2008-08-04 |
2015-11-10 |
Biodesy, Inc. |
Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
|
MX2011001409A
(es)
|
2008-08-14 |
2011-03-29 |
Cephalon Australia Pty Ltd |
Anticuerpos anti-il-12/il-23.
|
US8153391B2
(en)
|
2008-08-29 |
2012-04-10 |
Bunge Oils, Inc. |
Hydrolases, nucleic acids encoding them and methods for making and using them
|
US8198062B2
(en)
|
2008-08-29 |
2012-06-12 |
Dsm Ip Assets B.V. |
Hydrolases, nucleic acids encoding them and methods for making and using them
|
US8357503B2
(en)
|
2008-08-29 |
2013-01-22 |
Bunge Oils, Inc. |
Hydrolases, nucleic acids encoding them and methods for making and using them
|
US10131693B2
(en)
|
2008-10-20 |
2018-11-20 |
Gwangju Institute Of Science And Technology |
Bipodal-peptide binder
|
RU2011127198A
(ru)
*
|
2008-12-04 |
2013-01-10 |
Эбботт Лэборетриз |
Иммуноглобулины с двойными вариабельными доменами и их применение
|
US8492133B2
(en)
|
2009-01-20 |
2013-07-23 |
Ramot At Tel Aviv University, Ltd. |
MIR-21 promoter driven targeted cancer therapy
|
JP2012516153A
(ja)
*
|
2009-01-29 |
2012-07-19 |
アボット・ラボラトリーズ |
Il−1結合タンパク質
|
US20110165063A1
(en)
*
|
2009-01-29 |
2011-07-07 |
Abbott Laboratories |
Il-1 binding proteins
|
US8030026B2
(en)
|
2009-02-24 |
2011-10-04 |
Abbott Laboratories |
Antibodies to troponin I and methods of use thereof
|
TW201613969A
(en)
|
2009-03-05 |
2016-04-16 |
Abbvie Inc |
IL-17 binding proteins
|
EP3121271B1
(en)
|
2009-03-30 |
2019-07-24 |
Portola Pharmaceuticals, Inc. |
Antidotes for factor xa inhibitors and methods of using the same
|
GB0908770D0
(en)
|
2009-04-24 |
2009-07-01 |
Danisco |
Method
|
DK2698374T3
(en)
|
2009-05-21 |
2017-01-09 |
Basf Enzymes Llc |
Phytases, nucleic acids encoding them, and methods of making and using the same
|
PT2453910T
(pt)
|
2009-07-15 |
2016-12-07 |
Portola Pharm Inc |
Formulação de dose unitária de antídoto contra inibidores de fator xa para uso na prevenção de sangramento
|
TW201109438A
(en)
*
|
2009-07-29 |
2011-03-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
SG178930A1
(en)
*
|
2009-08-29 |
2012-04-27 |
Abbott Lab |
Therapeutic dll4 binding proteins
|
JP2013503607A
(ja)
|
2009-09-01 |
2013-02-04 |
アボット・ラボラトリーズ |
二重可変ドメイン免疫グロブリンおよびその使用
|
US20110082054A1
(en)
*
|
2009-09-14 |
2011-04-07 |
Dyax Corp. |
Libraries of genetic packages comprising novel hc cdr3 designs
|
US8926976B2
(en)
*
|
2009-09-25 |
2015-01-06 |
Xoma Technology Ltd. |
Modulators
|
CN102597775A
(zh)
|
2009-09-25 |
2012-07-18 |
佐马技术有限公司 |
筛选方法
|
CN102666875A
(zh)
|
2009-10-15 |
2012-09-12 |
雅培制药有限公司 |
双重可变结构域免疫球蛋白及其用途
|
UA109884C2
(uk)
|
2009-10-16 |
2015-10-26 |
|
Поліпептид, що має активність ферменту фосфатидилінозитол-специфічної фосфоліпази с, нуклеїнова кислота, що його кодує, та спосіб його виробництва і застосування
|
UA111708C2
(uk)
|
2009-10-16 |
2016-06-10 |
Бандж Ойлз, Інк. |
Спосіб рафінування олії
|
WO2011050194A1
(en)
|
2009-10-22 |
2011-04-28 |
Genentech, Inc. |
Methods and compositions for modulating hepsin activation of macrophage-stimulating protein
|
UY32979A
(es)
*
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
TW201121568A
(en)
|
2009-10-31 |
2011-07-01 |
Abbott Lab |
Antibodies to receptor for advanced glycation end products (RAGE) and uses thereof
|
EP2507264A2
(en)
|
2009-11-30 |
2012-10-10 |
F. Hoffmann-La Roche AG |
Antibodies for treating and diagnosing tumors expressing slc34a2 (tat211 = seqid 2)
|
ES2562832T3
(es)
*
|
2009-12-08 |
2016-03-08 |
Abbvie Deutschland Gmbh & Co Kg |
Anticuerpos monoclonales contra la proteína RGM para su uso en el tratamiento de la degeneración de la capa de fibra nerviosa de la retina
|
CN105001334A
(zh)
|
2010-02-10 |
2015-10-28 |
伊缪诺金公司 |
Cd20抗体及其用途
|
US9556249B2
(en)
|
2010-02-18 |
2017-01-31 |
Genentech, Inc. |
Neuregulin antagonists and use thereof in treating cancer
|
MX2012009215A
(es)
|
2010-02-23 |
2012-11-23 |
Genentech Inc |
Composiciones y metodos para el diagnostico y tratamiento de tumores.
|
KR101637138B1
(ko)
|
2010-02-24 |
2016-07-06 |
이뮤노젠 아이엔씨 |
엽산염 수용체 1 항체와 면역접합체 및 이들의 용도
|
AU2011223919B2
(en)
|
2010-03-02 |
2015-03-19 |
Abbvie Inc. |
Therapeutic DLL4 binding proteins
|
AU2011223527B2
(en)
|
2010-03-03 |
2014-11-13 |
Somalogic Operating Co., Inc. |
Aptamers to 4-1BB and their use in treating diseases and disorders
|
WO2011123507A1
(en)
|
2010-03-30 |
2011-10-06 |
Centocor Ortho Biotech Inc. |
Humanized il-25 antibodies
|
KR102185779B1
(ko)
|
2010-04-12 |
2020-12-03 |
소마로직, 인크. |
5-위치 변경된 피리미딘 및 그것의 용도
|
MX360403B
(es)
|
2010-04-15 |
2018-10-31 |
Abbvie Inc |
Proteinas de union a amiloide beta.
|
MA34291B1
(fr)
|
2010-05-03 |
2013-06-01 |
Genentech Inc |
Compositions et méthodes de diagnostic et de traitement d'une tumeur
|
PH12012502226A1
(en)
|
2010-05-14 |
2013-02-04 |
Abbvie Inc |
Il-1 binding proteins
|
GB201011513D0
(en)
|
2010-07-08 |
2010-08-25 |
Danisco |
Method
|
US20120009196A1
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
KR102024922B1
(ko)
|
2010-07-16 |
2019-09-25 |
아디맵 엘엘씨 |
항체 라이브러리
|
AU2011285852B2
(en)
|
2010-08-03 |
2014-12-11 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
EP2603524A1
(en)
|
2010-08-14 |
2013-06-19 |
AbbVie Inc. |
Amyloid-beta binding proteins
|
US9505829B2
(en)
|
2010-08-19 |
2016-11-29 |
Zoetis Belgium S.A. |
Anti-NGF antibodies and their use
|
US9046513B2
(en)
|
2010-08-26 |
2015-06-02 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
AR083355A1
(es)
|
2010-10-06 |
2013-02-21 |
Bp Corp North America Inc |
Polipeptidos variantes cbh i
|
KR20130133247A
(ko)
|
2010-12-21 |
2013-12-06 |
애브비 인코포레이티드 |
Il-1-알파 및 -베타 이특이적 이원 가변 도메인 면역글로불린 및 이의 용도
|
WO2012088094A2
(en)
|
2010-12-21 |
2012-06-28 |
Abbott Laboratories |
Il-1 binding proteins
|
DK2658970T3
(en)
|
2010-12-31 |
2017-01-16 |
Bioatla Llc |
Express humanization of antibodies
|
GB2503604B
(en)
|
2011-03-21 |
2020-04-22 |
Biodesy Llc |
Classification of kinase inhibitors using second harmonic optical techniques
|
MX383544B
(es)
|
2011-04-21 |
2025-03-14 |
Univ Rockefeller |
Lisinas de bacteriofago de streptococcus para la deteccion y tratamiento de bacterias gram positivas
|
SG10201505454SA
(en)
|
2011-07-13 |
2015-09-29 |
Abbvie Inc |
Methods and compositions for treating asthma using anti-il-13 antibodies
|
US8609355B2
(en)
|
2011-07-26 |
2013-12-17 |
Indicator Systems International, Inc. |
Assays for the detection of microbes
|
EP2756300A1
(en)
|
2011-09-15 |
2014-07-23 |
F.Hoffmann-La Roche Ag |
Methods of promoting differentiation
|
AU2012318609B2
(en)
|
2011-10-05 |
2018-02-08 |
The Rockefeller University |
Dimeric bacteriophage lysins
|
JP6254087B2
(ja)
|
2011-10-15 |
2017-12-27 |
ジェネンテック, インコーポレイテッド |
癌を治療するためのscd1アンタゴニスト
|
US8999331B2
(en)
|
2011-10-24 |
2015-04-07 |
Abbvie Inc. |
Immunobinders directed against sclerostin
|
WO2013078191A1
(en)
|
2011-11-23 |
2013-05-30 |
Medimmune, Llc |
Binding molecules specific for her3 and uses thereof
|
WO2013090633A2
(en)
|
2011-12-14 |
2013-06-20 |
AbbVie Deutschland GmbH & Co. KG |
Composition and method for the diagnosis and treatment of iron-related disorders
|
JP6342812B2
(ja)
|
2011-12-14 |
2018-06-13 |
アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー |
鉄関連障害を診断および治療するための組成物および方法
|
TW201333035A
(zh)
|
2011-12-30 |
2013-08-16 |
Abbvie Inc |
針對il-13及/或il-17之雙特異性結合蛋白
|
US20130183294A1
(en)
|
2012-01-18 |
2013-07-18 |
Genentech, Inc. |
Methods of using fgf19 modulators
|
MX359854B
(es)
|
2012-01-20 |
2018-10-12 |
Genzyme Corp |
Anticuerpos anti-cxcr3.
|
DK2807192T3
(en)
|
2012-01-27 |
2018-07-23 |
Abbvie Deutschland |
COMPOSITION AND PROCEDURE FOR DIAGNOSTICATION AND TREATMENT OF DISEASES RELATED TO NEURITE DEGENERATION
|
SG11201404703WA
(en)
|
2012-02-11 |
2014-09-26 |
Genentech Inc |
R-spondin translocations and methods using the same
|
AU2013229786B2
(en)
|
2012-03-08 |
2017-06-22 |
Halozyme, Inc. |
Conditionally active anti-epidermal growth factor receptor antibodies and methods of use thereof
|
CN104168898A
(zh)
|
2012-03-16 |
2014-11-26 |
霍夫曼-拉罗奇有限公司 |
以pak1抑制剂治疗黑色素瘤的方法
|
US9139863B2
(en)
|
2012-03-16 |
2015-09-22 |
Genentech, Inc. |
Engineered conformationally-stabilized proteins
|
HK1205524A1
(en)
|
2012-03-16 |
2015-12-18 |
F. Hoffmann-La Roche Ag |
Engineered conformationally-stabilized proteins
|
CA2867444C
(en)
|
2012-03-16 |
2021-04-13 |
University Health Network |
Compositions containing soluble toso protein and uses thereof
|
US9592289B2
(en)
|
2012-03-26 |
2017-03-14 |
Sanofi |
Stable IgG4 based binding agent formulations
|
JP6302460B2
(ja)
|
2012-04-25 |
2018-03-28 |
バイオデシー, インコーポレイテッド |
タンパク質のアロステリックモジュレーターを検出するための方法
|
WO2013170191A1
(en)
|
2012-05-11 |
2013-11-14 |
Genentech, Inc. |
Methods of using antagonists of nad biosynthesis from nicotinamide
|
KR101937733B1
(ko)
|
2012-05-24 |
2019-01-11 |
마운트게이트 그룹 리미티드 |
광견병 감염의 방지 및 치료에 관한 조성물 및 방법
|
JP6629069B2
(ja)
|
2012-06-06 |
2020-01-15 |
ゾエティス・エルエルシー |
イヌ化抗ngf抗体およびその方法
|
AR091755A1
(es)
|
2012-07-12 |
2015-02-25 |
Abbvie Inc |
Proteinas de union a il-1
|
AU2013308497B2
(en)
|
2012-08-31 |
2018-06-28 |
Immunogen Inc. |
Diagnostic assays and kits for detection of folate receptor 1
|
KR20190096459A
(ko)
|
2012-11-01 |
2019-08-19 |
애브비 인코포레이티드 |
항-vegf/dll4 이원 가변 도메인 면역글로불린 및 이의 용도
|
US9550986B2
(en)
|
2012-12-21 |
2017-01-24 |
Abbvie Inc. |
High-throughput antibody humanization
|
KR20150118159A
(ko)
|
2013-02-22 |
2015-10-21 |
에프. 호프만-라 로슈 아게 |
암의 치료 방법 및 약물 내성의 예방 방법
|
HK1213180A1
(zh)
|
2013-03-06 |
2016-06-30 |
豪夫迈‧罗氏有限公司 |
治疗和预防癌症药物抗性的方法
|
GB201308828D0
(en)
|
2013-03-12 |
2013-07-03 |
Verenium Corp |
Phytase
|
WO2014158272A1
(en)
|
2013-03-14 |
2014-10-02 |
Abbott Laboratories |
Hcv antigen-antibody combination assay and methods and compositions for use therein
|
RU2015139054A
(ru)
|
2013-03-14 |
2017-04-19 |
Дженентек, Инк. |
Способы лечения рака и профилактики лекарственной резистентности рака
|
MX2015012824A
(es)
|
2013-03-14 |
2016-06-24 |
Abbott Lab |
Antigenos recombinantes ns3 del vhc y mutantes de los mismos para la deteccion mejorada de anticuerpos.
|
GB201308843D0
(en)
|
2013-03-14 |
2013-07-03 |
Verenium Corp |
Phytase formulation
|
CA2906417C
(en)
|
2013-03-14 |
2022-06-21 |
Robert Ziemann |
Hcv core lipid binding domain monoclonal antibodies
|
WO2014144280A2
(en)
|
2013-03-15 |
2014-09-18 |
Abbvie Inc. |
DUAL SPECIFIC BINDING PROTEINS DIRECTED AGAINST IL-1β AND / OR IL-17
|
CN118547067A
(zh)
|
2013-03-15 |
2024-08-27 |
豪夫迈·罗氏有限公司 |
治疗pd-1和pd-l1相关疾患的生物标志物和方法
|
US9469686B2
(en)
|
2013-03-15 |
2016-10-18 |
Abbott Laboratories |
Anti-GP73 monoclonal antibodies and methods of obtaining the same
|
MX2015011899A
(es)
|
2013-03-15 |
2016-05-05 |
Genentech Inc |
Metodos para el tratamiento de cáncer y prevención de resistencia a los fármacos para el cáncer.
|
EP2971000A4
(en)
|
2013-03-15 |
2016-11-23 |
Pioneer Hi Bred Int |
PHI-4 POLYPEPTIDES AND METHOD FOR THEIR USE
|
WO2014197885A2
(en)
|
2013-06-07 |
2014-12-11 |
Duke University |
Inhibitors of complement factor h
|
JP2016525354A
(ja)
|
2013-07-25 |
2016-08-25 |
ビーエーエスエフ エンザイムズ エルエルシー |
フィターゼ
|
CN106232820A
(zh)
|
2013-08-16 |
2016-12-14 |
先锋国际良种公司 |
杀昆虫蛋白及其使用方法
|
AU2014312086B2
(en)
|
2013-08-30 |
2020-03-12 |
Immunogen, Inc. |
Antibodies and assays for detection of folate receptor 1
|
CN105764924A
(zh)
|
2013-09-12 |
2016-07-13 |
哈洛齐梅公司 |
修饰的抗表皮生长因子受体抗体及其使用方法
|
CA3175984A1
(en)
|
2013-09-13 |
2015-03-19 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
SMT202200233T1
(it)
|
2013-12-24 |
2022-07-21 |
Janssen Pharmaceutica Nv |
Anticorpi e frammenti anti-vista
|
WO2015116902A1
(en)
|
2014-01-31 |
2015-08-06 |
Genentech, Inc. |
G-protein coupled receptors in hedgehog signaling
|
MX2016010187A
(es)
|
2014-02-07 |
2017-07-11 |
Pioneer Hi Bred Int |
Proteinas insecticidas y metodos para su uso.
|
US10480007B2
(en)
|
2014-02-07 |
2019-11-19 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins from plants
|
EP3616718A1
(en)
|
2014-03-07 |
2020-03-04 |
University Health Network |
Methods and compositions for modifying the immune response
|
KR102546611B1
(ko)
|
2014-04-08 |
2023-06-22 |
보스턴 파마슈티칼즈, 아이엔씨. |
Il-21에 특이적인 결합 분자 및 이들 용도
|
RU2016144176A
(ru)
|
2014-04-11 |
2018-05-14 |
МЕДИММЬЮН, ЭлЭлСи |
Биспецифические антитела к her2
|
GB201406767D0
(en)
|
2014-04-15 |
2014-05-28 |
Cancer Rec Tech Ltd |
Humanized anti-Tn-MUC1 antibodies anf their conjugates
|
MX386644B
(es)
|
2014-05-05 |
2025-03-19 |
Regeneron Pharma |
Animales c5 y c3 humanizados.
|
CA2944717A1
(en)
|
2014-05-23 |
2015-11-26 |
Genentech, Inc. |
Mit biomarkers and methods using the same
|
EP3154589A1
(en)
|
2014-06-13 |
2017-04-19 |
Genentech, Inc. |
Methods of treating and preventing cancer drug resistance
|
EP3157945A4
(en)
|
2014-06-20 |
2017-11-22 |
F. Hoffmann-La Roche AG |
Chagasin-based scaffold compositions, methods, and uses
|
MX381370B
(es)
|
2014-10-16 |
2025-03-12 |
Corteva Agriscience Llc |
Proteinas insecticidas y metodos de uso.
|
EP3172329A1
(en)
|
2014-10-24 |
2017-05-31 |
Danisco US Inc. |
Method for producing alcohol by use of a tripeptidyl peptidase
|
EP3209774B1
(en)
|
2014-10-24 |
2020-02-26 |
DuPont Nutrition Biosciences ApS |
Use of proline tolerant tripeptidyl peptidases in feed additive compositions
|
EP3218406B2
(en)
|
2014-11-10 |
2024-10-02 |
Medimmune Limited |
Binding molecules specific for cd73 and uses thereof
|
JP6847037B2
(ja)
|
2014-11-11 |
2021-03-24 |
メディミューン リミテッド |
抗cd73抗体とa2a受容体阻害薬とを含む併用治療薬及びその使用
|
WO2016094881A2
(en)
|
2014-12-11 |
2016-06-16 |
Abbvie Inc. |
Lrp-8 binding proteins
|
EP3237906B8
(en)
|
2014-12-23 |
2020-10-28 |
Bluelight Therapeutics, Inc. |
Attachment of proteins to interfaces for use in nonlinear optical detection
|
SG11201705721WA
(en)
|
2015-01-14 |
2017-08-30 |
Brigham & Womens Hospital Inc |
Treatment of cancer with anti-lap monoclonal antibodies
|
AU2016207026B2
(en)
|
2015-01-15 |
2021-12-02 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
US10876132B2
(en)
|
2015-03-11 |
2020-12-29 |
Pioneer Hi-Bred International, Inc. |
Insecticidal combinations of PIP-72 and methods of use
|
CN107787332B
(zh)
|
2015-04-24 |
2022-09-09 |
豪夫迈·罗氏有限公司 |
多特异性抗原结合蛋白
|
BR112017024948A2
(pt)
|
2015-05-19 |
2018-07-31 |
Pioneer Hi Bred Int |
proteínas inseticidas e métodos para uso das mesmas
|
AU2016270640B2
(en)
|
2015-05-29 |
2022-03-10 |
Abbvie Inc. |
Anti-CD40 antibodies and uses thereof
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
CA2990360C
(en)
|
2015-06-24 |
2024-02-13 |
Janssen Pharmaceutica Nv |
Anti-vista antibodies and fragments
|
EP3314004A1
(en)
|
2015-06-26 |
2018-05-02 |
DuPont Nutrition Biosciences ApS |
Aminopeptidases for protein hydrolyzates
|
KR102663480B1
(ko)
|
2015-06-29 |
2024-05-23 |
이뮤노젠 아이엔씨 |
항-cd123 항체 및 이들의 접합체와 유도체
|
US10287338B2
(en)
|
2015-07-10 |
2019-05-14 |
Miran NERSISSIAN |
Factor VIII protein compositions and methods of treating of hemophilia A
|
CA2993009A1
(en)
|
2015-07-31 |
2017-02-09 |
Research Institute At Nationwide Children's Hospital |
Peptides and antibodies for the removal of biofilms
|
US11198709B2
(en)
|
2015-08-06 |
2021-12-14 |
E. I. Du Pont De Nemours And Company |
Plant derived insecticidal proteins and methods for their use
|
WO2017066719A2
(en)
|
2015-10-14 |
2017-04-20 |
Research Institute At Nationwide Children's Hospital |
Hu specific interfering agents
|
EP3374398B1
(en)
|
2015-11-10 |
2020-03-18 |
MedImmune, LLC |
Binding molecules specific for asct2 and uses thereof
|
CN108575091A
(zh)
|
2015-12-18 |
2018-09-25 |
先锋国际良种公司 |
杀昆虫蛋白及其使用方法
|
WO2017112955A1
(en)
|
2015-12-23 |
2017-06-29 |
Pharma Llc Moonshot |
Methods for inducing an immune response by inhibition of nonsense mediated decay
|
JP2019509993A
(ja)
|
2016-02-12 |
2019-04-11 |
ヤンセン ファーマシューティカ エヌブイ |
抗vista(b7h5)抗体
|
MX2018009216A
(es)
|
2016-02-25 |
2018-11-09 |
Dupont Nutrition Biosci Aps |
Metodo para producir un hidrolizado de proteina empleando una tripeptidil peptidasa de aspergillus fumigatus.
|
EP3426680B1
(en)
|
2016-03-10 |
2024-08-14 |
Acceleron Pharma Inc. |
Activin type 2 receptor binding proteins and uses thereof
|
WO2017161206A1
(en)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugates containing conditionally active antibodies or antigen-binding fragments thereof, and methods of use
|
US10765724B2
(en)
|
2016-03-29 |
2020-09-08 |
Janssen Biotech, Inc. |
Method of treating psoriasis with increased interval dosing of anti-IL12/23 antibody
|
WO2017175058A1
(en)
|
2016-04-07 |
2017-10-12 |
Janssen Pharmaceutica Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
KR20220080015A
(ko)
|
2016-04-22 |
2022-06-14 |
악셀레론 파마 인코포레이티드 |
Alk7 결합 단백질 및 이들의 용도
|
JP6871948B2
(ja)
|
2016-04-27 |
2021-05-19 |
アッヴィ・インコーポレイテッド |
抗il−13抗体を使用する、il−13活性が有害である疾患の治療方法
|
BR112018072417B1
(pt)
|
2016-05-04 |
2023-03-14 |
E. I. Du Pont De Nemours And Company |
Polipeptídeo inseticida recombinante, polipeptídeo quimérico, composição, polinucleotídeo recombinante, construtos de dna, métodos para obter uma planta transgênica, métodos para inibir o crescimento ou extermínio de uma praga de inseto ou população de praga, método para obter uma célula procariótica transformada, célula procariótica transformada e método para modificar geneticamente o polipeptídeo inseticida
|
CN109476699B
(zh)
|
2016-06-02 |
2021-10-12 |
艾伯维公司 |
糖皮质激素受体激动剂及其免疫偶联物
|
AU2017279539A1
(en)
|
2016-06-08 |
2019-01-03 |
Abbvie Inc. |
Anti-B7-H3 antibodies and antibody drug conjugates
|
EP3469000A1
(en)
|
2016-06-08 |
2019-04-17 |
AbbVie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
RS61828B1
(sr)
|
2016-06-08 |
2021-06-30 |
Abbvie Inc |
Anti-b7-h3 antitela i antitelske konjugacije lekova
|
GB201610198D0
(en)
|
2016-06-10 |
2016-07-27 |
Ucb Biopharma Sprl |
Anti-ige antibodies
|
EP3472186A1
(en)
|
2016-06-17 |
2019-04-24 |
National Hellenic Research Foundation |
Systems for recombinant protein production
|
EP3478052B1
(en)
|
2016-07-01 |
2021-08-25 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins from plants and methods for their use
|
CN110198729A
(zh)
|
2016-09-09 |
2019-09-03 |
豪夫迈·罗氏有限公司 |
卷曲蛋白的选择性肽抑制剂
|
IL316408A
(en)
|
2016-09-30 |
2025-01-01 |
Janssen Biotech Inc |
A safe and effective method for treating psoriasis with a specific anti-IL23 antibody
|
BR112019006710A2
(pt)
|
2016-10-03 |
2019-06-25 |
Abbott Lab |
métodos aprimorados para avaliação do estado da uch-l1 em amostras de pacientes
|
CN109863167B
(zh)
|
2016-11-01 |
2022-12-23 |
先锋国际良种公司 |
杀昆虫蛋白及其使用方法
|
KR20240065333A
(ko)
|
2016-11-16 |
2024-05-14 |
얀센 바이오테크 인코포레이티드 |
항-il23 특이적 항체로 건선을 치료하는 방법
|
EP3544628A4
(en)
|
2016-11-23 |
2020-11-18 |
Immunoah Therapeutics, Inc. |
4-1BB BINDING PROTEINS AND THEIR USES
|
CN110662770A
(zh)
|
2016-11-23 |
2020-01-07 |
比奥维拉迪维治疗股份有限公司 |
结合凝血因子ix和凝血因子x的双特异性抗体
|
WO2018111551A1
(en)
|
2016-12-14 |
2018-06-21 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
WO2018118811A1
(en)
|
2016-12-22 |
2018-06-28 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
US20180230218A1
(en)
|
2017-01-04 |
2018-08-16 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
AU2018206560B9
(en)
|
2017-01-04 |
2025-04-03 |
Research Institute At Nationwide Children's Hospital |
Antibody fragments for the treatment of biofilm-related disorders
|
AU2018206552C1
(en)
|
2017-01-04 |
2025-04-10 |
Research Institute At Nationwide Children's Hospital |
DNABII vaccines and antibodies with enhanced activity
|
JP7069476B2
(ja)
|
2017-01-06 |
2022-05-18 |
博奥信生物技▲術▼(南京)有限公司 |
ErbB2抗体およびその使用
|
IL268007B2
(en)
|
2017-01-30 |
2025-05-01 |
Janssen Biotech Inc |
Anti-tnf antibodies, compositions, and methods for the treatment of active psoriatic arthritis
|
MX2019009377A
(es)
|
2017-02-07 |
2019-12-11 |
Janssen Biotech Inc |
Anticuerpos anti-tnf, composiciones y metodos para el tratamiento de la espondilitis anquilosante activa.
|
US20190390219A1
(en)
|
2017-02-08 |
2019-12-26 |
Pioneer Hi-Bred International, Inc. |
Insecticidal combinations of plant derived insecticidal proteins and methods for their use
|
WO2018152496A1
(en)
|
2017-02-17 |
2018-08-23 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Compositions and methods for the diagnosis and treatment of zika virus infection
|
WO2018157027A1
(en)
|
2017-02-27 |
2018-08-30 |
Regeneron Pharmaceuticals, Inc. |
Humanized model of kidney and liver disorders
|
AU2018236271B2
(en)
|
2017-03-15 |
2023-12-21 |
Research Institute At Nationwide Children's Hospital |
Composition and methods for disruption of bacterial biofilms without accompanying inflammation
|
JP7346300B2
(ja)
|
2017-03-23 |
2023-09-19 |
アボット・ラボラトリーズ |
早期バイオマーカーであるユビキチンカルボキシ末端ヒドロラーゼl1を使用する、ヒト対象における外傷性脳損傷の程度の診断及び決定の一助となるための方法
|
WO2018191531A1
(en)
|
2017-04-15 |
2018-10-18 |
Abbott Laboratories |
Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury in a human subject using early biomarkers
|
CA3059615A1
(en)
|
2017-04-21 |
2018-10-25 |
Genentech, Inc. |
Use of klk5 antagonists for treatment of a disease
|
EP4230649A3
(en)
|
2017-04-25 |
2023-10-25 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Antibodies and methods for the diagnosis and treatment of epstein barr virus infection
|
CN110603449A
(zh)
|
2017-04-28 |
2019-12-20 |
雅培实验室 |
用同一人受试者的至少两种样品的早期生物标记物帮助超急性诊断确定创伤性脑损伤的方法
|
US10865238B1
(en)
|
2017-05-05 |
2020-12-15 |
Duke University |
Complement factor H antibodies
|
UA126807C2
(uk)
|
2017-05-11 |
2023-02-08 |
Піонір Хай-Бред Інтернешнл, Інк. |
Інсектицидний білок і спосіб його застосування
|
AU2018272054B2
(en)
|
2017-05-25 |
2024-10-31 |
Abbott Laboratories |
Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers
|
BR112019025387A2
(pt)
|
2017-05-30 |
2020-07-07 |
Abbott Laboratories |
métodos para auxiliar no diagnóstico e avaliação de uma lesão traumática cerebral branda em um indivíduo humano com o uso de troponina cardíaca i e biomarcadores precoces
|
US11654135B2
(en)
|
2017-06-22 |
2023-05-23 |
Moonshot Pharma Llc |
Methods for treating colon cancer with compositions comprising amlexanox and immune checkpoint inhibitors
|
EP3649474A1
(en)
|
2017-07-03 |
2020-05-13 |
Abbott Laboratories |
Improved methods for measuring ubiquitin carboxy-terminal hydrolase l1 levels in blood
|
WO2019018629A1
(en)
|
2017-07-19 |
2019-01-24 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
ANTIBODIES AND METHODS FOR DIAGNOSING AND TREATING INFECTION WITH HEPATITIS B VIRUS
|
JP6889328B2
(ja)
|
2017-07-31 |
2021-06-18 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
三次元構造に基づくヒト化方法
|
KR20240034260A
(ko)
|
2017-09-05 |
2024-03-13 |
이뮤노젠 아이엔씨 |
환자 샘플에서 엽산 수용체 1의 검출 방법
|
TW201922780A
(zh)
|
2017-09-25 |
2019-06-16 |
美商健生生物科技公司 |
以抗il12/il23抗體治療狼瘡之安全且有效之方法
|
CN118497126A
(zh)
|
2017-10-04 |
2024-08-16 |
赫斯佩瑞克斯股份公司 |
针对癌症个体化疗法的制品和方法
|
WO2019075090A1
(en)
|
2017-10-10 |
2019-04-18 |
Tilos Therapeutics, Inc. |
ANTI-LAP ANTIBODIES AND USES THEREOF
|
AU2018360789A1
(en)
|
2017-11-06 |
2020-05-14 |
Janssen Biotech, Inc. |
Safe and effective method of treating psoriatic arthritis with anti-IL-23 specific antibody
|
AU2018364630A1
(en)
|
2017-11-09 |
2020-05-21 |
Pinteon Therapeutics Inc. |
Methods and compositions for the generation and use of humanized conformation-specific phosphorylated tau antibodies
|
WO2019113525A2
(en)
|
2017-12-09 |
2019-06-13 |
Abbott Laboratories |
Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (tbi), using glial fibrillary acidic protein (gfap) and/or ubiquitin carboxy-terminal hydrolase l1 (uch-l1)
|
CN110892266A
(zh)
|
2017-12-09 |
2020-03-17 |
雅培实验室 |
使用gfap和uch-l1的组合辅助诊断和评价人类受试者中创伤性脑损伤的方法
|
WO2019126472A1
(en)
|
2017-12-22 |
2019-06-27 |
Genentech, Inc. |
Use of pilra binding agents for treatment of a disease
|
JP7437303B2
(ja)
|
2017-12-29 |
2024-02-22 |
アボット・ラボラトリーズ |
外傷性脳損傷を診断及び査定するための、新規のバイオマーカー及び方法
|
WO2019150309A1
(en)
|
2018-02-02 |
2019-08-08 |
Hammack Scott |
Modulators of gpr68 and uses thereof for treating and preventing diseases
|
US11512127B2
(en)
|
2018-02-14 |
2022-11-29 |
Viela Bio, Inc. |
Antibodies to Feline McDonough Sarcoma (FMS)-like tyrosine kinase 3 receptor ligand (FLT3L) and uses thereof for treating autoimmune and inflammatory diseases
|
AU2019232624B2
(en)
|
2018-03-05 |
2025-03-06 |
Janssen Biotech, Inc. |
Methods of treating Crohn's disease with anti-IL23 specific antibody
|
CA3093772C
(en)
|
2018-03-12 |
2024-04-16 |
Zoetis Services Llc |
Anti-ngf antibodies and methods thereof
|
CN115850420A
(zh)
|
2018-03-14 |
2023-03-28 |
先锋国际良种公司 |
来自植物的杀昆虫蛋白及其使用方法
|
US11820791B2
(en)
|
2018-03-14 |
2023-11-21 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins from plants and methods for their use
|
WO2019213619A1
(en)
|
2018-05-04 |
2019-11-07 |
Abbott Laboratories |
Hbv diagnostic, prognostic, and therapeutic methods and products
|
WO2019222226A2
(en)
|
2018-05-17 |
2019-11-21 |
Bp Corporation North America Inc. |
Production of 2-keto-3-deoxy-d-gluconic acid in filamentous fungi
|
AU2019282671B2
(en)
|
2018-06-08 |
2021-05-06 |
Crystal Bioscience Inc. |
Transgenic animal for producing diversified antibodies that have the same light chain i
|
WO2019241002A1
(en)
|
2018-06-13 |
2019-12-19 |
Crystal Bioscience Inc. |
Transgenic chicken that makes antibodies with long cdr-h3s stabilized by multiple disulfide bridges and diversified by gene conversion
|
US12129298B2
(en)
|
2018-06-21 |
2024-10-29 |
Daiichi Sankyo Company, Limited |
Compositions including CD3 antigen binding fragments and uses thereof
|
WO2020014306A1
(en)
|
2018-07-10 |
2020-01-16 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
JP7634474B2
(ja)
|
2018-07-18 |
2025-02-21 |
ヤンセン バイオテツク,インコーポレーテツド |
抗il23特異的抗体で治療した後の持続応答予測因子
|
WO2020041360A1
(en)
|
2018-08-21 |
2020-02-27 |
Quidel Corporation |
Dbpa antibodies and uses thereof
|
WO2020049157A1
(en)
|
2018-09-07 |
2020-03-12 |
Basf Plant Science Company Gmbh |
Improved method for the production of high levels of pufa in plants
|
CN112969792A
(zh)
|
2018-09-07 |
2021-06-15 |
巴斯夫植物科学有限公司 |
用于在植物中产生高水平pufa的改进方法
|
CN113412332A
(zh)
|
2018-09-07 |
2021-09-17 |
巴斯夫植物科学有限公司 |
用于在植物中产生高水平pufa的改进方法
|
HRP20230886T1
(hr)
|
2018-09-24 |
2023-11-24 |
Janssen Biotech, Inc. |
Siguran i učinkovit postupak za liječenje ulcerativnog kolitisa s protutijelom anti-il12/il23
|
AU2019355194A1
(en)
|
2018-10-05 |
2021-04-22 |
Research Institute At Nationwide Children's Hospital |
Compositions and methods for enzymatic disruption of bacterial biofilms
|
TW202035445A
(zh)
|
2018-10-10 |
2020-10-01 |
美商帝洛斯療法股份有限公司 |
抗lap抗體變異體及其用途
|
US20220332800A1
(en)
|
2018-11-20 |
2022-10-20 |
Takeda Vaccines, Inc. |
Novel anti-zika virus antibodies and uses thereof
|
MA55149A
(fr)
|
2018-11-20 |
2021-09-29 |
Janssen Biotech Inc |
Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique anti-il-23
|
US20200197517A1
(en)
|
2018-12-18 |
2020-06-25 |
Janssen Biotech, Inc. |
Safe and Effective Method of Treating Lupus with Anti-IL12/IL23 Antibody
|
EP3897117A1
(en)
|
2018-12-21 |
2021-10-27 |
Compass Therapeutics LLC |
Transgenic mouse expressing common human light chain
|
CN113574066A
(zh)
|
2019-01-15 |
2021-10-29 |
詹森生物科技公司 |
用于治疗幼年特发性关节炎的抗tnf抗体组合物和方法
|
AU2020210962A1
(en)
|
2019-01-23 |
2021-07-22 |
Janssen Biotech, Inc. |
anti-TNF antibody compositions for use in methods for the treatment of Psoriatic Arthritis
|
WO2020185763A1
(en)
|
2019-03-11 |
2020-09-17 |
Memorial Sloan Kettering Cancer Center |
Cd22 antibodies and methods of using the same
|
US12180271B2
(en)
|
2019-03-14 |
2024-12-31 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-TNF antibody compositions
|
KR20210141990A
(ko)
|
2019-03-14 |
2021-11-23 |
얀센 바이오테크 인코포레이티드 |
항-il12/il23 항체 조성물을 생성하기 위한 제조 방법
|
EA202192505A1
(ru)
|
2019-03-14 |
2022-03-29 |
Янссен Байотек, Инк. |
Способы получения композиций антитела к фно
|
US12129292B2
(en)
|
2019-03-14 |
2024-10-29 |
Janssen Biotech, Inc. |
Anti-tumor necrosis factor (TNF) antibodies and compositions thereof
|
JP2022526493A
(ja)
|
2019-03-18 |
2022-05-25 |
ヤンセン バイオテツク,インコーポレーテツド |
抗il12/il23抗体を用いた小児被験者の乾癬の治療方法
|
KR20220005568A
(ko)
|
2019-05-09 |
2022-01-13 |
제넨테크, 인크. |
항체의 제조 방법
|
JP2022534020A
(ja)
|
2019-05-23 |
2022-07-27 |
ヤンセン バイオテツク,インコーポレーテツド |
Il-23及びtnfアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
|
KR20220030952A
(ko)
|
2019-06-03 |
2022-03-11 |
얀센 바이오테크 인코포레이티드 |
활성 강직성 척추염의 치료를 위한 항-tnf 항체, 조성물, 및 방법
|
US20220323580A1
(en)
|
2019-06-03 |
2022-10-13 |
Janssen Biotech, Inc. |
Anti-tnf antibody compositions, and methods for the treatment of psoriatic arthritis
|
CA3145385A1
(en)
|
2019-07-08 |
2021-01-14 |
Steven D. Goodman |
Antibody compositions for disrupting biofilms
|
WO2021028752A1
(en)
|
2019-08-15 |
2021-02-18 |
Janssen Biotech, Inc. |
Anti-tfn antibodies for treating type i diabetes
|
WO2021127547A2
(en)
|
2019-12-19 |
2021-06-24 |
Quidel Corporation |
Monoclonal antibody fusions
|
EP4077658A1
(en)
|
2019-12-20 |
2022-10-26 |
Basf Se |
Decreasing toxicity of terpenes and increasing the production potential in micro-organisms
|
KR20220137698A
(ko)
|
2020-02-05 |
2022-10-12 |
라리마 테라퓨틱스, 인코포레이티드 |
Tat 펩티드 결합 단백질 및 이의 용도
|
EP4132971A1
(en)
|
2020-04-09 |
2023-02-15 |
Merck Sharp & Dohme LLC |
Affinity matured anti-lap antibodies and uses thereof
|
WO2021211331A1
(en)
|
2020-04-13 |
2021-10-21 |
Abbott Point Of Care Inc. |
METHODS, COMPLEXES AND KITS FOR DETECTING OR DETERMINING AN AMOUNT OF A ß-CORONAVIRUS ANTIBODY IN A SAMPLE
|
WO2021221783A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
US20210338833A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Chimeric antigen receptor-targeting ligands and uses thereof
|
CA3181949A1
(en)
|
2020-05-05 |
2021-11-11 |
Janssen Biotech, Inc. |
Methods of treating crohn's disease with anti-il23 specific antibody
|
BR112022022986A2
(pt)
|
2020-05-13 |
2023-01-17 |
Disc Medicine Inc |
Anticorpos anti-hemojuvelina (hjv) para tratar mielofibrose
|
CA3183927A1
(en)
|
2020-05-21 |
2021-11-25 |
Janssen Biotech, Inc. |
Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha
|
BR112022024475A2
(pt)
|
2020-06-04 |
2022-12-27 |
Isobionics B V |
Beta santaleno sintase sintética, ácido nucleico sintético, cassete de expressão, método para produzir uma composição, célula hospedeira não humana, composição, e, uso de qualquer uma das santaleno sintases sintéticas
|
EP4182466A2
(en)
|
2020-07-14 |
2023-05-24 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
WO2022024065A1
(en)
|
2020-07-30 |
2022-02-03 |
Janssen Biotech, Inc. |
Method of treating psoriasis in pediatric subjects with anti-il12/il23 antibody
|
EP4193151A1
(en)
|
2020-08-04 |
2023-06-14 |
Abbott Rapid Diagnostics International Unlimited Company |
Assays for detecting sars-cov-2
|
US20220043000A1
(en)
|
2020-08-04 |
2022-02-10 |
Abbott Laboratories |
Methods and kits for detecting sars-cov-2 protein in a sample
|
KR20230084497A
(ko)
|
2020-09-11 |
2023-06-13 |
메디뮨 리미티드 |
치료용 b7-h4 결합 분자
|
IL301264A
(en)
|
2020-09-12 |
2023-05-01 |
Medimmune Ltd |
A scoring method for an anti-b7h4 antibody-drug conjugate therapy
|
US20230374591A1
(en)
|
2020-10-08 |
2023-11-23 |
The Trustees Of Dartmouth College |
Methods and agents for treating, preventing, diagnosing, and evaluating therapy for fibrotic, autoimmune, and inflammatory conditions
|
WO2022119841A1
(en)
|
2020-12-01 |
2022-06-09 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
WO2023102384A1
(en)
|
2021-11-30 |
2023-06-08 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
EP4015626A1
(en)
|
2020-12-18 |
2022-06-22 |
Isobionics B.V. |
Enzymes and methods for fermentative production of monoterpene esters
|
EP4271998A1
(en)
|
2020-12-30 |
2023-11-08 |
Abbott Laboratories |
Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
|
TW202245844A
(zh)
|
2021-01-13 |
2022-12-01 |
紀念斯隆凱特琳癌症中心 |
抗dll3抗體-藥物結合物
|
MX2023008261A
(es)
|
2021-01-13 |
2023-09-12 |
Memorial Sloan Kettering Cancer Center |
Conjugado de anticuerpo-derivado de pirrolobenzodiazepina.
|
AR124681A1
(es)
|
2021-01-20 |
2023-04-26 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
MX2023010705A
(es)
|
2021-03-12 |
2023-11-22 |
Janssen Biotech Inc |
Método seguro y eficaz para tratar la artritis psoriásica con el anticuerpo específico anti-il23.
|
CA3213278A1
(en)
|
2021-03-12 |
2022-09-15 |
Janssen Biotech, Inc. |
Method of treating psoriatic arthritis patients with inadequate response to tnf therapy with anti-il23 specific antibody
|
CN117203232A
(zh)
|
2021-03-17 |
2023-12-08 |
瑞塞普托斯有限责任公司 |
用抗il-13抗体治疗特应性皮炎的方法
|
US20240174758A1
(en)
|
2021-03-18 |
2024-05-30 |
Medimmune Limited |
Therapeutic binding molecules
|
WO2022241057A1
(en)
|
2021-05-12 |
2022-11-17 |
Applied Biomedical Science Institute |
Binding polypeptides against sars cov-2 and uses thereof
|
CA3216320A1
(en)
|
2021-05-18 |
2022-11-24 |
Abbott Laboratories |
Methods of evaluating brain injury in a pediatric subject
|
EP4340875A1
(en)
|
2021-05-20 |
2024-03-27 |
Janssen Biotech, Inc. |
Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha
|
BR112023026199A2
(pt)
|
2021-06-14 |
2024-03-05 |
Abbott Lab |
Métodos para diagnosticar ou auxiliar no diagnóstico de lesão cerebral causada por energia acústica, energia eletromagnética, onda de sobrepressurização e/ou rajada de vento
|
CN117957251A
(zh)
|
2021-07-09 |
2024-04-30 |
詹森生物科技公司 |
用于制备抗tnf抗体组合物的制造方法
|
EP4367138A1
(en)
|
2021-07-09 |
2024-05-15 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-il12/il23 antibody compositions
|
WO2023281462A1
(en)
|
2021-07-09 |
2023-01-12 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-tnf antibody compositions
|
EP4381085A2
(en)
|
2021-08-02 |
2024-06-12 |
Basf Se |
Novel production of aroma compounds with ionylideneethane synthases
|
US11807685B2
(en)
|
2021-08-05 |
2023-11-07 |
The Uab Research Foundation |
Anti-CD47 antibody and uses thereof
|
EP4392783A1
(en)
|
2021-08-27 |
2024-07-03 |
Abbott Laboratories |
Methods for detecting immunoglobulin g, subclass 4 (igg4) in a biological sample
|
JP2024534849A
(ja)
|
2021-08-31 |
2024-09-26 |
アボット・ラボラトリーズ |
脳の損傷を診断する方法及びシステム
|
CN118715440A
(zh)
|
2021-08-31 |
2024-09-27 |
雅培实验室 |
诊断脑损伤的方法和系统
|
WO2023056268A1
(en)
|
2021-09-30 |
2023-04-06 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
MX2024005197A
(es)
|
2021-10-29 |
2024-07-24 |
Janssen Biotech Inc |
Métodos para tratar la enfermedad de crohn con el anticuerpo específico anti-il23.
|
US20230151087A1
(en)
|
2021-11-15 |
2023-05-18 |
Janssen Biotech, Inc. |
Methods of Treating Crohn's Disease with Anti-IL23 Specific Antibody
|
EP4436997A1
(en)
|
2021-11-23 |
2024-10-02 |
Janssen Biotech, Inc. |
Method of treating ulcerative colitis with anti-il23 specific antibody
|
JP2025503439A
(ja)
|
2021-12-17 |
2025-02-04 |
アボット・ラボラトリーズ |
血液試料におけるuch-l1、gfap及び他のバイオマーカーを決定するためのシステム及び方法
|
CN119256227A
(zh)
|
2022-02-04 |
2025-01-03 |
雅培实验室 |
用于检测样品中泛素羧基末端水解酶l1和/或胶质纤维酸性蛋白的存在或测量其量的侧向流方法、测定和装置
|
TW202348252A
(zh)
|
2022-02-16 |
2023-12-16 |
英商梅迪繆思有限公司 |
用治療性結合分子治療癌症的組合療法
|
US20230312703A1
(en)
|
2022-03-30 |
2023-10-05 |
Janssen Biotech, Inc. |
Method of Treating Psoriasis with IL-23 Specific Antibody
|
WO2023223265A1
(en)
|
2022-05-18 |
2023-11-23 |
Janssen Biotech, Inc. |
Method for evaluating and treating psoriatic arthritis with il23 antibody
|
JP2025524496A
(ja)
|
2022-06-29 |
2025-07-30 |
アボット・ラボラトリーズ |
生体試料におけるgfapを決定するための磁気ポイントオブケアシステム及びアッセイ
|
EP4587842A1
(en)
|
2022-09-15 |
2025-07-23 |
Abbott Laboratories |
Biomarkers and methods for differentiating between mild and supermild traumatic brain injury
|
AU2023343487A1
(en)
|
2022-09-15 |
2025-03-20 |
Abbott Laboratories |
Hbv diagnostic, prognostic, and therapeutic methods and products
|
US20240199734A1
(en)
|
2022-11-22 |
2024-06-20 |
Janssen Biotech, Inc. |
Method of Treating Ulcerative Colitis with Anti-IL23 Specific Antibody
|
WO2024211475A1
(en)
|
2023-04-04 |
2024-10-10 |
Abbott Laboratories |
Use of biomarkers to determine whether a subject has sustained, may have sustained or is suspected of sustaining a subacute acquired brain injury (abi)
|
WO2024226971A1
(en)
|
2023-04-28 |
2024-10-31 |
Abbott Point Of Care Inc. |
Improved assays, cartridges, and kits for detection of biomarkers, including brain injury biomarkers
|
TW202448936A
(zh)
|
2023-05-03 |
2024-12-16 |
美商健生生物科技公司 |
以針對IL-23及TNF α的抗體的組合來治療潰瘍性結腸炎之方法
|
TW202508626A
(zh)
|
2023-05-03 |
2025-03-01 |
美商健生生物科技公司 |
以針對IL-23及TNFα的抗體的組合來治療克隆氏症之方法
|
TW202448509A
(zh)
|
2023-05-12 |
2024-12-16 |
美商建南德克公司 |
減少抗體黏度之方法及組成物
|
US20250051463A1
(en)
|
2023-07-31 |
2025-02-13 |
Astrazeneca Ab |
Cd123 antibody-drug conjugates and methods of using the same
|
WO2025184208A1
(en)
|
2024-02-27 |
2025-09-04 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|