CA3225456A1 - Human mesothelin chimeric antigen receptors and uses thereof - Google Patents

Human mesothelin chimeric antigen receptors and uses thereof Download PDF

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Publication number
CA3225456A1
CA3225456A1 CA3225456A CA3225456A CA3225456A1 CA 3225456 A1 CA3225456 A1 CA 3225456A1 CA 3225456 A CA3225456 A CA 3225456A CA 3225456 A CA3225456 A CA 3225456A CA 3225456 A1 CA3225456 A1 CA 3225456A1
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Canada
Prior art keywords
seq
sequence
mesothelin
amino acid
acid sequence
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Pending
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CA3225456A
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English (en)
French (fr)
Inventor
Gregory Beatty
Boris ENGELS
Neeraja Idamakanti
Carl H. June
Andreas Loew
Huijuan SONG
Qilong WU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
University of Pennsylvania Penn
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Novartis AG
University of Pennsylvania Penn
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Publication of CA3225456A1 publication Critical patent/CA3225456A1/en
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    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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CA3225456A 2013-12-19 2014-12-19 Human mesothelin chimeric antigen receptors and uses thereof Pending CA3225456A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CN2013089979 2013-12-19
CNPCT/CN2013/089979 2013-12-19
CN2014082610 2014-07-21
CNPCT/CN2014/082610 2014-07-21
CN2014090509 2014-11-06
CNPCT/CN2014/090509 2014-11-06
CA2931684A CA2931684C (en) 2013-12-19 2014-12-19 Human mesothelin chimeric antigen receptors and uses thereof

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