MX2016008076A - Receptores quimericos de antigeno de mesotelina humana y uso de los mismos. - Google Patents

Receptores quimericos de antigeno de mesotelina humana y uso de los mismos.

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Publication number
MX2016008076A
MX2016008076A MX2016008076A MX2016008076A MX2016008076A MX 2016008076 A MX2016008076 A MX 2016008076A MX 2016008076 A MX2016008076 A MX 2016008076A MX 2016008076 A MX2016008076 A MX 2016008076A MX 2016008076 A MX2016008076 A MX 2016008076A
Authority
MX
Mexico
Prior art keywords
chimeric antigen
mesothelin
antigen receptors
car
human mesothelin
Prior art date
Application number
MX2016008076A
Other languages
English (en)
Spanish (es)
Inventor
H June Carl
Loew Andreas
Beatty Gregory
ENGELS Boris
IDAMAKANTI Neeraja
Song Huijuan
Wu Qilong
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2016008076A publication Critical patent/MX2016008076A/es

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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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    • A61K39/0011Cancer antigens
    • A61K39/001166Adhesion molecules, e.g. NRCAM, EpCAM or cadherins
    • A61K39/001168Mesothelin [MSLN]
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    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/7151Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
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    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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MX2016008076A 2013-12-19 2014-12-19 Receptores quimericos de antigeno de mesotelina humana y uso de los mismos. MX2016008076A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN2013089979 2013-12-19
CN2014082610 2014-07-21
CN2014090509 2014-11-06
PCT/CN2014/094393 WO2015090230A1 (en) 2013-12-19 2014-12-19 Human mesothelin chimeric antigen receptors and uses thereof

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MX2016008076A true MX2016008076A (es) 2016-08-12

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