CA2999420A1 - Amniotic membrane preparations and purified compositions and methods of use - Google Patents

Amniotic membrane preparations and purified compositions and methods of use Download PDF

Info

Publication number
CA2999420A1
CA2999420A1 CA2999420A CA2999420A CA2999420A1 CA 2999420 A1 CA2999420 A1 CA 2999420A1 CA 2999420 A CA2999420 A CA 2999420A CA 2999420 A CA2999420 A CA 2999420A CA 2999420 A1 CA2999420 A1 CA 2999420A1
Authority
CA
Canada
Prior art keywords
cndot
human
human amniotic
homogenate
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2999420A
Other languages
English (en)
French (fr)
Inventor
Scheffer Tseng
Hua He
Wei Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BioTissue Holdings Inc
Original Assignee
TissueTech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TissueTech Inc filed Critical TissueTech Inc
Publication of CA2999420A1 publication Critical patent/CA2999420A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/738—Cross-linked polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/982—Reproductive organs; Embryos, Eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4718—Cytokine-induced proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/64—Animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Materials Engineering (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
CA2999420A 2005-09-27 2006-09-27 Amniotic membrane preparations and purified compositions and methods of use Abandoned CA2999420A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72076005P 2005-09-27 2005-09-27
US60/720,760 2005-09-27
CA2949643A CA2949643C (en) 2005-09-27 2006-09-27 Amniotic membrane preparations and purified compositions and methods of use

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2949643A Division CA2949643C (en) 2005-09-27 2006-09-27 Amniotic membrane preparations and purified compositions and methods of use

Publications (1)

Publication Number Publication Date
CA2999420A1 true CA2999420A1 (en) 2007-04-05

Family

ID=37900469

Family Applications (3)

Application Number Title Priority Date Filing Date
CA2999420A Abandoned CA2999420A1 (en) 2005-09-27 2006-09-27 Amniotic membrane preparations and purified compositions and methods of use
CA2623940A Expired - Fee Related CA2623940C (en) 2005-09-27 2006-09-27 Amniotic membrane preparations and purified compositions and methods of use
CA2949643A Expired - Fee Related CA2949643C (en) 2005-09-27 2006-09-27 Amniotic membrane preparations and purified compositions and methods of use

Family Applications After (2)

Application Number Title Priority Date Filing Date
CA2623940A Expired - Fee Related CA2623940C (en) 2005-09-27 2006-09-27 Amniotic membrane preparations and purified compositions and methods of use
CA2949643A Expired - Fee Related CA2949643C (en) 2005-09-27 2006-09-27 Amniotic membrane preparations and purified compositions and methods of use

Country Status (9)

Country Link
US (14) US8182840B2 (enExample)
EP (2) EP1933852B1 (enExample)
JP (2) JP5505760B2 (enExample)
CN (2) CN101316602B (enExample)
AU (1) AU2006294581B2 (enExample)
CA (3) CA2999420A1 (enExample)
DK (1) DK1933852T3 (enExample)
ES (1) ES2713062T3 (enExample)
WO (1) WO2007038686A2 (enExample)

Families Citing this family (137)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7932365B2 (en) 2003-11-08 2011-04-26 Pro Thera Biologics, Llc Preparation and composition of inter-alpha inhibitor proteins from human plasma for therapeutic use
JP5505760B2 (ja) 2005-09-27 2014-05-28 ティッシュテク・インコーポレーテッド 羊膜調製物及び精製組成物及びその使用方法
US8187639B2 (en) 2005-09-27 2012-05-29 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
US8372437B2 (en) 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
US8071135B2 (en) * 2006-10-04 2011-12-06 Anthrogenesis Corporation Placental tissue compositions
EP2197270B8 (en) 2007-09-07 2020-03-04 Surgical Biologics, LLC Placental tissue grafts and improved methods of preparing and using the same
WO2009111159A2 (en) * 2008-03-03 2009-09-11 New York University Biocompatible materials containing stable complexes of tsg-6 and hyaluronan and method of using same
US9480549B2 (en) 2008-04-25 2016-11-01 Allosource Multi-layer tissue patches
US9358320B2 (en) 2008-04-25 2016-06-07 Allosource Multi-layer tissue patches
JP5793076B2 (ja) 2008-05-28 2015-10-14 プロセラ バイオロジクス， インコーポレイテッド 血液由来インター−アルファ−阻害タンパク質の調製及び組成物。
EP2421901B1 (en) * 2009-04-24 2015-10-28 Tissue Tech, Inc. Compositions containing hc ha complex and methods of use thereof
US8859003B2 (en) * 2009-06-05 2014-10-14 Intercontinental Great Brands Llc Preparation of an enteric release system
US20100307542A1 (en) * 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Method of Reducing Surface Oil on Encapsulated Material
US20100310726A1 (en) 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Novel Preparation of an Enteric Release System
US9968564B2 (en) 2009-06-05 2018-05-15 Intercontinental Great Brands Llc Delivery of functional compounds
EP3827788A1 (en) * 2009-07-10 2021-06-02 Implantica Patent Ltd. Hip joint device and method
CN101658491B (zh) * 2009-09-24 2011-04-13 哈尔滨医科大学 一种治疗角膜碱烧伤的羊膜滴眼液
WO2011103462A1 (en) 2010-02-18 2011-08-25 Osiris Therapeutics, Inc. Methods of manufacture of immunocompatible amniotic membrane products
KR101869077B1 (ko) 2010-05-03 2018-06-22 더 텍사스 에이 & 엠 유니버시티 시스템 눈 손상 및 질환 치료용 성체 줄기 세포／전구 세포 및 줄기 세포 단백질
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
JP6124791B2 (ja) 2010-09-22 2017-05-10 ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド，ア ボディー コーポレイトＴＨＥ ＲＥＧＥＮＴＳ ＯＦ ＴＨＥ ＵＮＩＶＥＲＳＩＴＹ ＯＦ ＣＯＬＯＲＡＤＯ，ａ ｂｏｄｙ ｃｏｒｐｏｒａｔｅ Ｓｍａｄ７の治療的適用
EP3744336B1 (en) 2011-02-14 2025-01-01 MiMedx Group, Inc. Micronized placental tissue compositions and methods for making and using the same
AU2012217982B2 (en) 2011-02-14 2016-05-12 Mimedx Group Inc. Tissue grafts modified with a cross-linking agent and method of making and using the same
US9526770B2 (en) 2011-04-28 2016-12-27 Tissuetech, Inc. Methods of modulating bone remodeling
US9682044B2 (en) 2011-06-10 2017-06-20 Tissuetech, Inc. Methods of processing fetal support tissues, fetal support tissue powder products, and uses thereof
US9439940B2 (en) * 2011-07-19 2016-09-13 Neville Pharmaceutical, Inc. Topical transdermal method for delivering nutrients through the skin for expeditied wound healing and skin rejuvenation
US9931423B2 (en) 2011-08-26 2018-04-03 Tissuetech, Inc. Methods of sterilizing fetal support tissues
US12290613B2 (en) 2011-10-06 2025-05-06 Mimedx Group, Inc. Micronized compositions composed of bone grafts and methods of making and using the same
US8932805B1 (en) 2011-10-31 2015-01-13 BioDlogics, LLC Birth tissue material and method of preparation
US9162011B2 (en) 2011-12-19 2015-10-20 Allosource Flowable matrix compositions and methods
EP2793745B1 (en) 2011-12-22 2019-07-31 MIMEDX Group Inc. Cross-linked dehydrated placental tissue grafts and methods for making and using the same
US8961617B2 (en) 2012-03-08 2015-02-24 Liventa Bioscience, Inc. Amnion and chorion constructs and uses thereof in abdominal surgery
US20130236506A1 (en) * 2012-03-08 2013-09-12 AFcell Medical Amnion and chorion constructs and uses thereof in ob-gyn surgery
US9295753B1 (en) 2012-07-02 2016-03-29 Celso Tello Amniotic membrane preparation and device for use as a lens or as a dressing for promoting healing
ES2846789T3 (es) * 2012-07-11 2021-07-29 Tissuetech Inc Composiciones que contienen complejos HC-HA/PTX3 y métodos de uso de los mismos
US11338063B2 (en) 2012-08-15 2022-05-24 Mimedx Group, Inc. Placental tissue grafts modified with a cross-linking agent and methods of making and using the same
US8904664B2 (en) 2012-08-15 2014-12-09 Mimedx Group, Inc. Dehydration device and methods for drying biological materials
WO2014028657A1 (en) 2012-08-15 2014-02-20 Mimedx Group, Inc Reinforced placental tissue grafts and methods of making and using the same
US9943551B2 (en) 2012-08-15 2018-04-17 Mimedx Group, Inc. Tissue grafts composed of micronized placental tissue and methods of making and using the same
US9572872B2 (en) 2012-09-09 2017-02-21 Prothera Biologics, Inc. Treatment of disease using inter-alpha inhibitor proteins
WO2014040026A2 (en) 2012-09-10 2014-03-13 Wake Forest University Health Sciences Amniotic membrane and its use in wound healing and tissue engineering constructs
US9180145B2 (en) 2012-10-12 2015-11-10 Mimedx Group, Inc. Compositions and methods for recruiting and localizing stem cells
US9155799B2 (en) 2012-11-19 2015-10-13 Mimedx Group, Inc. Cross-linked collagen with at least one bound antimicrobial agent for in vivo release of the agent
US8946163B2 (en) 2012-11-19 2015-02-03 Mimedx Group, Inc. Cross-linked collagen comprising metallic anticancer agents
US8859005B2 (en) 2012-12-03 2014-10-14 Intercontinental Great Brands Llc Enteric delivery of functional ingredients suitable for hot comestible applications
CA2897662C (en) 2013-01-09 2022-07-26 Ryanne EARLY Decellularized biomaterial from non-mammalian tissue
US10517931B2 (en) 2013-01-17 2019-12-31 Mimedx Group, Inc. Non-surgical, localized delivery of compositions for placental growth factors
US9827293B2 (en) 2013-01-17 2017-11-28 Mimedx Group, Inc. Non-surgical, localized delivery of compositions for placental growth factors
US9655948B1 (en) 2013-01-17 2017-05-23 Mimedx Group, Inc. Non-surgical, localized delivery of compositions for placental growth factors
US10206977B1 (en) 2013-01-18 2019-02-19 Mimedx Group, Inc. Isolated placental stem cell recruiting factors
WO2014113733A1 (en) 2013-01-18 2014-07-24 Mimedx Group, Inc. Methods for treating cardiac conditions
US9422352B2 (en) 2013-03-08 2016-08-23 The Regents Of The University Of Colorado, A Body Corporate PTD-SMAD7 therapeutics
US11077229B1 (en) 2013-03-08 2021-08-03 BioDlogics, LLC Implant coating composition and method of use
EP2968646B1 (en) 2013-03-13 2019-05-29 AlloSource Fascia fibrous compositions and methods for their use and manufacture
US10016459B1 (en) 2013-03-13 2018-07-10 BioDlogics, LLC Platelet-rich plasma derived from human umbilical cord blood
US9511119B2 (en) * 2013-03-15 2016-12-06 NuTech Spine, Inc. Preparations containing hepatocyte growth factor and hyaluronic acid and methods of making and using same
WO2014143990A1 (en) 2013-03-15 2014-09-18 NuTech Medical, Inc. Preparations derived from placental materials of making and using same
WO2014150784A1 (en) 2013-03-15 2014-09-25 Allosource Cell repopulated collagen matrix for soft tissue repair and regeneration
US10029030B2 (en) 2013-03-15 2018-07-24 Mimedx Group, Inc. Molded placental tissue compositions and methods of making and using the same
US10039792B1 (en) 2013-03-16 2018-08-07 Brahm Holdings, Llc Methods for the treatment of inflammation and pain using human birth tissue material composition
US10555897B1 (en) 2013-03-16 2020-02-11 Brahm Holdings Llc Cosmetic composition and methods of treatment
US9993506B1 (en) 2013-03-16 2018-06-12 BioDlogics, Inc. Methods for the treatment of degenerative disc diseases by human birth tissue material composition
US9795639B1 (en) 2013-03-16 2017-10-24 BioDlogics, LLC Methods for the treatment of erectile dysfunction by human birth tissue material compostion
HK1221402A1 (zh) * 2013-04-02 2017-06-02 University Of Florida Research Foundation, Inc. 用於诱导并调节血管生成的组合物和方法以及用於鉴别血管生成调节剂的方法和实验
WO2015171880A1 (en) * 2014-05-08 2015-11-12 The University Of Florida Research Foundation, Inc. Sustained release angiogenesis modulating compositions and methods for induction and modulation of angiogenesis
US9446142B2 (en) 2013-05-28 2016-09-20 Mimedx Group, Inc. Polymer chelator conjugates
US20160230142A1 (en) * 2013-09-17 2016-08-11 Singapore Health Services Pte Ltd Corneal stromal keratocyte culture
US9795707B2 (en) 2013-12-06 2017-10-24 Allosource Methods of drying sheets of donor-provided human birth tissue
JP7464348B2 (ja) 2014-01-17 2024-04-09 ミメディクス グループ インコーポレイテッド 血管新生を誘導する方法
US10894066B2 (en) 2014-03-06 2021-01-19 Amnio Technology Llc Amnion derived therapeutic compositions and methods of use
US9132156B1 (en) 2014-06-15 2015-09-15 Amnio Technology Llc Acellular amnion derived therapeutic compositions
TW201603818A (zh) 2014-06-03 2016-02-01 組織科技股份有限公司 組成物及方法
WO2015189266A1 (en) * 2014-06-10 2015-12-17 Ludwig Boltzmann Gesellschaft Biocompatibility assay
WO2015195508A1 (en) * 2014-06-15 2015-12-23 Amnio Technology Llc Frozen therapeutic dose and package
US10363278B2 (en) 2014-06-15 2019-07-30 Amnio Technology Llc Frozen therapeutic dose and package
EP3185918B1 (en) 2014-08-28 2021-08-18 MiMedx Group, Inc. Collagen reinforced tissue grafts
WO2016040385A1 (en) * 2014-09-09 2016-03-17 Mimedx Group, Inc. Micronized placental tissue compositions with optional sealant and methods of making and using the same
CA2963273C (en) * 2014-10-02 2023-10-17 Wake Forest University Health Sciences Amniotic membrane powder and its use in wound healing and tissue engineering constructs
US20160095307A1 (en) 2014-10-07 2016-04-07 NuTech Medical, Inc. Method and composition for hypothermic storage of placental tissue
CN107106542B (zh) 2014-10-20 2020-05-08 奥伊斯特普安生物制药公司 治疗眼部病状的方法
US10201573B1 (en) 2014-10-27 2019-02-12 Brahm Holdings, Llc Human birth tissue material composition and methods for the treatment of damage associated with a cerebral vascular accident
US10265438B1 (en) 2014-11-03 2019-04-23 BioDlogics, LLC Methods and compositions for the repair and replacement of connective tissue
JP2017533917A (ja) * 2014-11-05 2017-11-16 ティッシュテック，インク． 神経成長および再生を促進するための組成物および方法
US10765705B2 (en) 2014-11-24 2020-09-08 Prime Merger Sub, Llc Visco-supplement compositions, and methods of use thereof
WO2016109821A1 (en) * 2014-12-31 2016-07-07 Applied Biologics, Llc Reconstituted amniotic membrane-amniotic fluid combination tissue graft
WO2016109824A1 (en) * 2014-12-31 2016-07-07 Applied Biologics, Llc Reconstituted amniotic membrane-amniotic fluid combination tissue graft with standardized stem cell component
WO2016111899A1 (en) * 2015-01-05 2016-07-14 Petrucci Gary M Methods and materials for treating lung disorders
US10517903B2 (en) 2015-09-14 2019-12-31 Amnio Technology Llc Amnion derived therapeutic composition and process of making same
EP3247381A4 (en) * 2015-01-23 2018-08-01 Puretein Bioscience, LLC Methods for treating inflammation with tgf-beta
US10736990B2 (en) * 2015-02-11 2020-08-11 Mimedx Group, Inc. Collagen and micronized placental tissue compositions and methods of making and using the same
US20160243288A1 (en) 2015-02-23 2016-08-25 Tissuetech, Inc. Apparatuses and methods for treating ophthalmic diseases and disorders
US11077149B1 (en) * 2015-03-04 2021-08-03 Pensara, Inc Method for the collection and use of amniotic fluid
US10342831B2 (en) 2015-05-20 2019-07-09 Tissuetech, Inc. Composition and methods for preventing the proliferation and epithelial-mesenchymal transition of epithelial cells
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
US12551509B2 (en) 2015-11-18 2026-02-17 Lucina Patent Holdco, Llc Acellular regenerative products and methods of their manufacture
CN105356107A (zh) * 2015-11-27 2016-02-24 上海斐讯数据通信技术有限公司 一种终端接口、终端插条、插接组件和多用插接组件
TW201733600A (zh) 2016-01-29 2017-10-01 帝聖工業公司 胎兒扶持組織物及使用方法
US10993969B2 (en) 2016-02-05 2021-05-04 Gary M. Petrucci Methods and materials for treating nerve injuries and neurological disorders
AU2017235220B2 (en) * 2016-03-14 2022-03-24 Plakous Therapeutics, Inc. Acellular placental preparations
CA3036553A1 (en) 2016-09-13 2018-03-22 Prothera Biologics, Inc. Methods for treating pulmonary disease using inter-alpha inhibitor proteins
JP2018102744A (ja) 2016-12-27 2018-07-05 オムロン株式会社 袋状構造体、カフ及び血圧計
US10772986B2 (en) 2017-01-26 2020-09-15 Allosource Fascia fibrous compositions and methods for their use and manufacture
US10960028B2 (en) 2017-02-01 2021-03-30 Plakous Therapeutics, Inc. Placental tissue compositions
KR102587810B1 (ko) 2017-04-25 2023-10-11 프로테라 바이오로직스, 인크. 인터-알파 억제제 단백질을 정량화하는 방법
JP6373444B1 (ja) * 2017-05-10 2018-08-15 株式会社ホルス 羊膜由来原料の製造方法、化粧品の製造方法及び健康食品の製造方法
US10478531B2 (en) 2017-06-22 2019-11-19 Gary M. Petrucci Methods and materials for treating blood vessels
RU176257U1 (ru) * 2017-09-18 2018-01-12 Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации Спейсер для реконструктивной пластики века
US20190083547A1 (en) * 2017-09-19 2019-03-21 Gary M. Petrucci Transdermal delivery of amnion tissue preparations
US10251917B1 (en) 2017-09-19 2019-04-09 Gary M. Petrucci Methods and materials for treating tumors
CN109528772A (zh) * 2017-09-22 2019-03-29 中国福利会国际和平妇幼保健院 人羊膜上皮细胞分泌因子在制备修复卵巢功能的药物中的应用
CZ307603B6 (cs) 2017-12-27 2019-01-02 BioHealing k.s. Způsob přípravy materiálu na bázi amniové membrány a materiál připravitelný tímto způsobem
JP7454379B2 (ja) * 2017-12-28 2024-03-22 株式会社カネカ 接着性幹細胞を含む細胞集団とその製造方法、及び医薬組成物
US11285177B2 (en) 2018-01-03 2022-03-29 Globus Medical, Inc. Allografts containing viable cells and methods thereof
GB201800909D0 (en) * 2018-01-19 2018-03-07 Biocel Ltd Compositions and methods relating to amnion
CA3088129A1 (en) * 2018-01-26 2019-08-01 Polarityte, Inc. Composite-interfacing biomaterial accelerant substrate
US11026980B1 (en) * 2018-02-26 2021-06-08 Triad Life Sciences, Inc. Flowable birth tissue composition and related methods
TW202000196A (zh) * 2018-03-01 2020-01-01 日商石原產業股份有限公司 保存安定性優異之醫藥組成物
CA3097470A1 (en) * 2018-04-18 2019-10-24 i.com medical GmbH High molecular weight hyaluronic acid for enhancing epithelial survival and reconstitution of body surfaces
CN110090228A (zh) * 2018-04-18 2019-08-06 浙江大学 人羊膜上皮细胞在自身免疫性疾病中的治疗用途
JP7433245B2 (ja) * 2018-05-18 2024-02-19 ミメディクス グループ インコーポレイテッド 皮膚の欠陥の治療のための胎盤組織成分組成物およびそれを使用する方法
CN109157676A (zh) * 2018-08-31 2019-01-08 谭亚 一种重塑复合生物羊膜的制备方法
US20220152120A1 (en) * 2019-04-16 2022-05-19 Lifenet Health Birth tissue-derived products and preparation and uses thereof
US12195755B2 (en) 2019-05-20 2025-01-14 Brown University Placental lipid bilayer for cell-free molecular interaction studies
WO2021087008A1 (en) 2019-10-28 2021-05-06 Brown University Bacterial beta-lactamase responsive hydrogels
KR20220143689A (ko) * 2020-02-12 2022-10-25 티슈테크, 인코포레이티드 암 세포를 사멸시키거나 성장을 억제하는 방법
CN112063577B (zh) * 2020-08-14 2023-05-16 中国医科大学附属第一医院 用于胰岛培养的组合培养基及其制备方法
KR20230119117A (ko) * 2020-10-26 2023-08-16 바이오티슈 홀딩스 인코포레이티드 태아 지지 조직의 처리 방법
EP4401785A4 (en) * 2021-09-15 2025-11-05 Univ Colorado Regents SMAD7 POLYPEPTIDE FORMULATIONS
EP4440638A1 (en) * 2021-11-30 2024-10-09 Riccio, Michele Production process of a pulverized scaffold
CZ309798B6 (cs) * 2022-03-15 2023-10-18 Prime Cell Bioscience, a.s Způsob přípravy biologického léčivého přípravku na bázi perinatální tkáně, práškový materiál a jeho použití
US20250262249A1 (en) * 2022-04-20 2025-08-21 Biostem Technologies, Inc. Multi-part processed human amniotic composition and methods of making and using thereof for treatment of peyronie's disease
WO2023211823A1 (en) 2022-04-25 2023-11-02 Biotissue Holdings Inc. Compositions and methods relating to pooled fetal support tissue
CN114939190B (zh) * 2022-06-14 2024-01-12 健诺维(成都)生物科技有限公司 一种用于青光眼治疗的引流管材料及其制备方法
WO2023244218A1 (en) * 2022-06-14 2023-12-21 Verdon Michael Injectable connective tissue biologic implant
CN116077530B (zh) * 2022-11-21 2024-08-09 中南大学 预处理的人羊膜上皮细胞在制备治疗和/或预防炎症疾病药物中的应用

Family Cites Families (265)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1006620A (en) 1911-10-24 Gen Electric Tungsten-furnace.
US1023208A (en) 1908-12-30 1912-04-16 Ludwig Weiss Process for the production of pyrophorous substances for ignition and illumination.
US1003979A (en) 1910-06-13 1911-09-26 Massey Harris Co Ltd Clutch mechanism.
US1031468A (en) 1910-10-04 1912-07-02 Nicholas Power Perforating-machine.
US1025865A (en) 1910-10-13 1912-05-07 Hampden Watch Company Balance staff and roller for watches.
US1022005A (en) 1911-03-02 1912-04-02 Bert Keiser Shrader Measuring device.
US1010539A (en) 1911-03-06 1911-12-05 Frank Vitali Wheel-tire.
US1027211A (en) 1911-03-23 1912-05-21 Robert L Moore Rail-joint.
US1026534A (en) 1911-06-28 1912-05-14 Fletcher H Waddill Auto cranking device.
US1025845A (en) 1911-12-14 1912-05-07 Harry A Thiberge Trap.
US3993073A (en) 1969-04-01 1976-11-23 Alza Corporation Novel drug delivery device
US3598122A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3710795A (en) 1970-09-29 1973-01-16 Alza Corp Drug-delivery device with stretched, rate-controlling membrane
US4069307A (en) 1970-10-01 1978-01-17 Alza Corporation Drug-delivery device comprising certain polymeric materials for controlled release of drug
JPS4943153B1 (enExample) 1970-12-05 1974-11-19
US3742051A (en) * 1971-06-02 1973-06-26 Rohm & Haas 3,5-dichloro-n-(1,1,dimethyl-2-propynyl)benzimidoyl halides and derivatives
US3731683A (en) 1971-06-04 1973-05-08 Alza Corp Bandage for the controlled metering of topical drugs to the skin
US3996934A (en) 1971-08-09 1976-12-14 Alza Corporation Medical bandage
US3742951A (en) 1971-08-09 1973-07-03 Alza Corp Bandage for controlled release of vasodilators
BE795384A (fr) 1972-02-14 1973-08-13 Ici Ltd Pansements
JPS4943153A (enExample) * 1972-08-31 1974-04-23
US3921636A (en) 1973-01-15 1975-11-25 Alza Corp Novel drug delivery device
US3909816A (en) 1974-04-29 1975-09-30 Lloyd L Teeters Flame and carbon monoxide sensor and alarm circuit
US3993072A (en) 1974-08-28 1976-11-23 Alza Corporation Microporous drug delivery device
IL47062A (en) 1975-04-10 1979-07-25 Yeda Res & Dev Process for diminishing antigenicity of tissues to be usedas transplants by treatment with glutaraldehyde
US3972995A (en) 1975-04-14 1976-08-03 American Home Products Corporation Dosage form
US4405616A (en) 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
JPS5251009A (en) 1975-10-17 1977-04-23 Morinaga Milk Ind Co Ltd Method of producing drug for treating marrow leukemia
US4077407A (en) 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4031894A (en) 1975-12-08 1977-06-28 Alza Corporation Bandage for transdermally administering scopolamine to prevent nausea
US4201210A (en) 1976-06-22 1980-05-06 The United States Of America As Represented By The Secretary Of Agriculture Veterinary ocular ring device for sustained drug release
US4060084A (en) 1976-09-07 1977-11-29 Alza Corporation Method and therapeutic system for providing chemotherapy transdermally
US4201211A (en) 1977-07-12 1980-05-06 Alza Corporation Therapeutic system for administering clonidine transdermally
CA1097233A (en) 1977-07-20 1981-03-10 George K. E. Gregory Packages
JPS5562012A (en) 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
US4230105A (en) 1978-11-13 1980-10-28 Merck & Co., Inc. Transdermal delivery of drugs
US4291015A (en) 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US4361552A (en) 1980-09-26 1982-11-30 Board Of Regents, The University Of Texas System Wound dressing
US4327725A (en) 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4347841A (en) 1981-03-11 1982-09-07 Human Oltoanyagtermelo Es Kutato Intezet Biological wound covering and method for producing same
US5116817A (en) 1982-12-10 1992-05-26 Syntex (U.S.A.) Inc. LHRH preparations for intranasal administration
US4476116A (en) 1982-12-10 1984-10-09 Syntex (U.S.A.) Inc. Polypeptides/chelating agent nasal compositions having enhanced peptide absorption
US4599226A (en) 1983-03-31 1986-07-08 Genetic Laboratories, Inc. Wound dressing comprising silver sulfadiazine incorporated in animal tissue and method of preparation
US4599084A (en) 1983-05-24 1986-07-08 American Hospital Supply Corp. Method of using biological tissue to promote even bone growth
US5093487A (en) 1986-01-06 1992-03-03 Mobay Corporation Low viscosity high molecular weight filter sterilizable hyaluronic acid
US4624848A (en) 1984-05-10 1986-11-25 Ciba-Geigy Corporation Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
GB8518301D0 (en) 1985-07-19 1985-08-29 Fujisawa Pharmaceutical Co Hydrodynamically explosive systems
US4829000A (en) 1985-08-30 1989-05-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Reconstituted basement membrane complex with biological activity
US5436135A (en) 1985-09-02 1995-07-25 Pasteur Merieux Serums Et Vaccins New preparation of placenta collagen, their extraction method and their applications
US4983396A (en) 1985-12-06 1991-01-08 Key Pharmaceuticals, Inc. Percutaneous penetration enhancer of oleic acid and 2-ethyl-1,3-hexanediol
IL80944A (en) * 1985-12-17 1994-10-07 Synergen Inc Boulder Colo U S Human placenta angiogenic factor capable of stimulating capillary endothelial cell protease synthesis, dna synthesis and migration
US5011692A (en) 1985-12-28 1991-04-30 Sumitomo Pharmaceuticals Company, Limited Sustained pulsewise release pharmaceutical preparation
US4886783A (en) 1986-01-31 1989-12-12 Nelson Research & Development Co. Penetration enhancers for transdermal delivery of systemic agents
US4801586A (en) 1986-04-23 1989-01-31 Nelson Research & Development Co. Penetration enhancers for transdermal delivery of systemic agents
US5118845A (en) 1986-09-29 1992-06-02 Whitby Research, Inc. Penetration enhancer for transdermal delivery of systemic agents
US5196410A (en) 1986-10-31 1993-03-23 Pfizer Inc. Transdermal flux enhancing compositions
DE3751254D1 (de) 1986-10-31 1995-05-24 Nippon Zeon Co Wundverband.
US4861764A (en) 1986-11-17 1989-08-29 Macro Chem. Corp. Percutaneous absorption enhancers, compositions containing same and method of use
GB8708009D0 (en) 1987-04-03 1987-05-07 Clayton Found Res Injectable soft tissue augmentation materials
US5312325A (en) 1987-05-28 1994-05-17 Drug Delivery Systems Inc Pulsating transdermal drug delivery system
US4968509A (en) 1987-07-27 1990-11-06 Mcneilab, Inc. Oral sustained release acetaminophen formulation and process
US5033252A (en) 1987-12-23 1991-07-23 Entravision, Inc. Method of packaging and sterilizing a pharmaceutical product
US5052558A (en) 1987-12-23 1991-10-01 Entravision, Inc. Packaged pharmaceutical product
DE3805459A1 (de) * 1988-02-22 1989-08-31 Biotest Pharma Gmbh Verfahren zur sterilisation von blut, plasma, blut- und plasmaderivaten, zellsuspensionen oder dgl.
US5135915A (en) 1988-10-14 1992-08-04 Genentech, Inc. Method for the treatment of grafts prior to transplantation using TGF-.beta.
IL92966A (en) 1989-01-12 1995-07-31 Pfizer Dispensing devices powered by hydrogel
US5075104A (en) 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
WO1991001720A1 (en) 1989-08-07 1991-02-21 Herman Wade Schlameus Composition and method of promoting hard tissue healing
US5192744A (en) * 1990-01-12 1993-03-09 Northwestern University Method of inhibiting angiogenesis of tumors
US5017381A (en) 1990-05-02 1991-05-21 Alza Corporation Multi-unit pulsatile delivery system
US5633009A (en) 1990-11-28 1997-05-27 Sano Corporation Transdermal administration of azapirones
EP0579742A4 (en) 1991-03-26 1994-07-13 Oregon State Product and method for improving keratinocyte adhesion to the dermis
ES2111065T5 (es) 1991-04-16 2005-06-16 Nippon Shinyaku Company, Limited Procedimiento para producir una dispersion solida.
CZ282760B6 (cs) 1991-11-22 1997-09-17 Procter And Gamble Pharmaceuticals, Inc. Risedronátové prostředky se zpožděným uvolňováním
US5229135A (en) 1991-11-22 1993-07-20 Prographarm Laboratories Sustained release diltiazem formulation
CN1072086A (zh) * 1992-02-22 1993-05-19 郝振林 烧烫伤创面生物覆盖膜的制备方法
JP3337488B2 (ja) 1992-03-06 2002-10-21 アベンティス ファーマ株式会社 切迫流産治療剤
US5461140A (en) 1992-04-30 1995-10-24 Pharmaceutical Delivery Systems Bioerodible polymers for solid controlled release pharmaceutical compositions
US5260068A (en) 1992-05-04 1993-11-09 Anda Sr Pharmaceuticals Inc. Multiparticulate pulsatile drug delivery system
CH684741A5 (de) * 1992-06-11 1994-12-15 Lucchini Lab Sa Verfahren zur Herstellung eines Extraktes.
US5323907A (en) 1992-06-23 1994-06-28 Multi-Comp, Inc. Child resistant package assembly for dispensing pharmaceutical medications
US5437287A (en) 1992-08-17 1995-08-01 Carbomedics, Inc. Sterilization of tissue implants using iodine
US5318513A (en) 1992-09-24 1994-06-07 Leib Martin L Canalicular balloon fixation stent
WO1994008568A1 (fr) 1992-10-16 1994-04-28 Nippon Shinyaku Co., Ltd. Procede pour fabriquer des matrices de cire
US5260069A (en) 1992-11-27 1993-11-09 Anda Sr Pharmaceuticals Inc. Pulsatile particles drug delivery system
US5686105A (en) 1993-10-19 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
IL112580A0 (en) 1994-02-24 1995-05-26 Res Dev Foundation Amniotic membrane graft of wrap to prevent adhesions or bleeding of internal organs
US6203755B1 (en) 1994-03-04 2001-03-20 St. Jude Medical, Inc. Electron beam sterilization of biological tissues
JPH10504555A (ja) 1994-08-23 1998-05-06 デーゲーエフ ストーエス アクチェンゲゼルシャフト 無味の加水分解コラーゲンの使用及びそれを含む薬剤
US5665378A (en) 1994-09-30 1997-09-09 Davis; Roosevelt Transdermal therapeutic formulation
US5567441A (en) 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
KR19990014865A (ko) 1995-05-17 1999-02-25 피터 이. 브래이브맨 소장에서의 소화 및 흡수를 증진시키기 위한, 지방산을 함유한조성물들
US5837284A (en) 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
US7632922B1 (en) 1995-12-22 2009-12-15 Amgen, Inc. Osteoprotegerin
US6929801B2 (en) 1996-02-19 2005-08-16 Acrux Dds Pty Ltd Transdermal delivery of antiparkinson agents
US6923983B2 (en) 1996-02-19 2005-08-02 Acrux Dds Pty Ltd Transdermal delivery of hormones
US6632648B1 (en) 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
US5632284A (en) 1996-05-22 1997-05-27 Graether; John M. Barrier eye drape and method of using same
US6152142A (en) * 1997-02-28 2000-11-28 Tseng; Scheffer C. G. Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries
US5932545A (en) 1997-03-17 1999-08-03 Abbott Laboratories Antiangiogenic drug to treat cancer, arthritis and retinopathy
US5840329A (en) 1997-05-15 1998-11-24 Bioadvances Llc Pulsatile drug delivery system
US6391452B1 (en) 1997-07-18 2002-05-21 Bayer Corporation Compositions for nasal drug delivery, methods of making same, and methods of removing residual solvent from pharmaceutical preparations
US5869090A (en) 1998-01-20 1999-02-09 Rosenbaum; Jerry Transdermal delivery of dehydroepiandrosterone
CN1054513C (zh) 1998-04-14 2000-07-19 姚炳坤 一种制作冻干羊胎素的方法
US6946144B1 (en) 1998-07-08 2005-09-20 Oryxe Transdermal delivery system
CN1203794A (zh) 1998-07-10 1999-01-06 聂怀顺 羊胎素冻干粉及其生产方法
JP4477156B2 (ja) * 1998-09-22 2010-06-09 李 鎭彪 オキシトシン受容体作用物質
US6096733A (en) 1998-12-10 2000-08-01 Virginia Lubkin Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application
US20030068815A1 (en) 1999-02-11 2003-04-10 Stone Kevin R. Sterilized xenograft tissue
US6395300B1 (en) 1999-05-27 2002-05-28 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
US6046160A (en) * 1999-07-22 2000-04-04 Deroyal Industries, Inc. Composition and method for enhancing wound healing
US6521179B1 (en) 1999-08-11 2003-02-18 Biomedical Design, Inc. Sterilization
US6573249B2 (en) 2000-02-15 2003-06-03 Alphamed Pharmaceutical Corp. Topical wound therapeutic compositions
US10281478B2 (en) 2000-04-06 2019-05-07 Wayne P. Franco Combination growth factor therapy and cell therapy for treatment of acute and chronic diseases of the organs
KR20010098716A (ko) 2000-04-19 2001-11-08 김재찬 안구표면질환 치료용 양막 추출물
US6277855B1 (en) 2000-04-21 2001-08-21 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with nicotinic acetylcholine receptor agonists
US6465014B1 (en) 2001-03-21 2002-10-15 Isp Investments Inc. pH-dependent sustained release, drug-delivery composition
US20020192272A1 (en) 2001-03-28 2002-12-19 Popp Karl F. Metronidazole pledgets
PT102589A (pt) 2001-03-30 2002-12-31 Ramos Maria Teresa Furtado Metodo para a preparacao de membranas amnioticas imunologicamente inertes
US20030180181A1 (en) 2002-02-01 2003-09-25 Teri Greib Methods for sterilizing tissue
TWI290055B (en) 2002-03-14 2007-11-21 Tissuetech Inc Amniotic membrane covering for a tissue surface and devices facilitating fastening of membranes
US20030187515A1 (en) 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
JP2006507297A (ja) * 2002-05-13 2006-03-02 チルドレンズ・ホスピタル・ロサンジェルス ケロイドおよび他の皮膚または内部創傷または病変における異常瘢痕形成の処置および予防
US20040091503A1 (en) 2002-08-20 2004-05-13 Genitrix, Llc Lectin compositions and methods for modulating an immune response to an antigen
ES2323127T3 (es) 2002-08-20 2009-07-07 Euro-Celtique S.A. Forma posologica transdermica que comprende un agente activo y una forma de sal y una forma de base libre de un antagonista.
WO2004026244A2 (en) * 2002-09-18 2004-04-01 Emiliano Ghinelli Use of a human amniotic membrane composition for prophylaxis and treatment of diseases and conditions of the eye and skin
CN1720055A (zh) 2002-10-04 2006-01-11 组织技术公司 视网膜上皮细胞在羊膜上的培养和移植
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
KR100794289B1 (ko) * 2002-11-08 2008-01-11 아이진 주식회사 Ｂｍｐ-7 폴리펩타이드를 포함하는 흉터 형성 억제제
US20190105352A9 (en) 2003-01-07 2019-04-11 DePuy Synthes Products, Inc. Treatment of intervertebral disc degeneration using human umbilical cord tissue-derived cells
US20060153928A1 (en) 2003-02-26 2006-07-13 Shigeru Kinoshita Aminion-origin medical material and method of preparing the same
US20110280838A1 (en) 2007-12-27 2011-11-17 Advanced Technologies And Regenerative Medicine, Llc Treatment of intervertebral disc degeneration using human umbilical cord tissue-derived cells
ES2569780T3 (es) 2003-06-27 2016-05-12 DePuy Synthes Products, Inc. Células posparto derivadas de tejido placentario y métodos de preparación y uso de las mismas
US7480530B2 (en) 2003-06-30 2009-01-20 Johnson & Johnson Consumer Companies, Inc. Device for treatment of barrier membranes
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
ITRM20030595A1 (it) * 2003-12-23 2005-06-24 Sigma Tau Ind Farmaceuti Uso della ptx3 o di un suo derivato funzionale da sola o in associazione con tsg6 per il trattamento di patologie degenarative dell'osso o della cartilagine e per il trattamento della infertilita' femminile.
WO2006026325A2 (en) 2004-08-26 2006-03-09 Pathak Chandrashekhar P Implantable tissue compositions and method
WO2006091546A2 (en) 2005-02-22 2006-08-31 The Johns Hopkins School Of Medicine Use of amniotic fluid (af) in treating ocular disease and injury
WO2006094247A2 (en) * 2005-03-02 2006-09-08 Tissuetech, Inc. Amniotic membrane extracts, compositions thereof, and methods of use
WO2007011693A2 (en) 2005-07-14 2007-01-25 Medistem Laboratories, Inc. Compositions of placentally-derived stem cells for the treatment of cancer
GB0514567D0 (en) 2005-07-15 2005-08-24 Univ Nottingham Surgical membrane
CN1903073A (zh) * 2005-07-26 2007-01-31 孙甜甜 胎元素保健品的制造方法
US8187639B2 (en) 2005-09-27 2012-05-29 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
JP5505760B2 (ja) 2005-09-27 2014-05-28 ティッシュテク・インコーポレーテッド 羊膜調製物及び精製組成物及びその使用方法
CA2627288C (en) 2005-10-26 2015-12-15 Jan-Eric W. Ahlfors Acellular bioabsorbable tissue regeneration matrices produced by incubating acellular blood products
CN101479377A (zh) 2005-12-22 2009-07-08 简·恩尼斯 来自冷冻的脐带组织的活细胞
US9944900B2 (en) 2006-01-18 2018-04-17 Hemacell Perfusion Pulsatile perfusion extraction method for non-embryonic pluripotent stem cells
US20180008649A1 (en) 2006-03-23 2018-01-11 Pluristem Ltd. Adherent stromal cells derived from placentas of multiple donors and uses thereof
US20080050814A1 (en) 2006-06-05 2008-02-28 Cryo-Cell International, Inc. Procurement, isolation and cryopreservation of fetal placental cells
US20070299386A1 (en) 2006-06-23 2007-12-27 Minu, L.L.C. Delivery of an ocular agent using iontophoresis
WO2008003042A2 (en) 2006-06-28 2008-01-03 The University Of Medicine And Dentistry Of New Jersey Amnion-derived stem cells and uses thereof
WO2008021391A1 (en) 2006-08-15 2008-02-21 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
US8372437B2 (en) 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
US20080131522A1 (en) 2006-10-03 2008-06-05 Qing Liu Use of placental biomaterial for ocular surgery
US8071135B2 (en) 2006-10-04 2011-12-06 Anthrogenesis Corporation Placental tissue compositions
AU2007318210B2 (en) 2006-10-06 2014-02-20 Celularity Inc. Native (telopeptide) placental collagen compositions
US20080102135A1 (en) 2006-10-28 2008-05-01 Franck Jean Ollivier Use of equine amniotic membrane in ophthalmic surgeries in veterinary medicine
AU2008230706A1 (en) 2007-03-27 2008-10-02 University Of Southern California Device which enhances the biological activity of locally applied growth factors with particular emphasis on those used for bone repair
DK3473260T3 (da) 2007-07-10 2020-12-21 Lifecell Corp Acellulære vævsmatrixs-sammensætninger til vævsreparation
EP2197270B8 (en) 2007-09-07 2020-03-04 Surgical Biologics, LLC Placental tissue grafts and improved methods of preparing and using the same
ES2392729T5 (es) 2007-09-19 2015-08-28 Pluristem Ltd. Células adherentes de tejidos adiposos o de placenta y uso de las mismas en terapia
WO2009111159A2 (en) 2008-03-03 2009-09-11 New York University Biocompatible materials containing stable complexes of tsg-6 and hyaluronan and method of using same
US9125735B2 (en) 2008-04-04 2015-09-08 Forsight Labs, Llc Method of correcting vision using corneal onlays
SI2331109T1 (sl) 2008-08-22 2013-10-30 Anthrogenesis Corporation Postopki in sestavki za zdravljenje okvar kosti s populacijami placentarnih celic
WO2010071862A1 (en) 2008-12-19 2010-06-24 Ethicon, Incorporated Umbilical cord tissue derived cells for treating neuropathic pain and spasticity
US20190054125A1 (en) 2008-12-19 2019-02-21 DePuy Synthes Products, Inc. hUTC MODULATION OF PRO-INFLAMMATORY MEDIATORS OF LUNG AND PULMONARY DISEASES AND DISORDERS
EP2421901B1 (en) 2009-04-24 2015-10-28 Tissue Tech, Inc. Compositions containing hc ha complex and methods of use thereof
EP2437684B1 (en) 2009-06-03 2022-06-15 ForSight Vision5, Inc. Anterior segment drug delivery
WO2011031489A2 (en) 2009-08-25 2011-03-17 Tissuetech, Inc. Umbilical cord amniotic membrane products
WO2011103462A1 (en) 2010-02-18 2011-08-25 Osiris Therapeutics, Inc. Methods of manufacture of immunocompatible amniotic membrane products
KR20130092394A (ko) 2010-04-08 2013-08-20 안트로제네시스 코포레이션 태반 줄기 세포를 사용한 사르코이드증의 치료
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
ES2634545T3 (es) 2010-06-01 2017-09-28 Auxocell Laboratories, Inc. Células madre nativas de la gelatina de Wharton y su purificación
US8840665B2 (en) 2010-06-11 2014-09-23 Liventa Bioscience, Inc. Method of tendon repair with amnion and chorion constructs
US20130156863A1 (en) 2010-06-30 2013-06-20 Tissuetech, Inc. Methods of preparing chorion tissue and products derived therefrom
US20120003296A1 (en) 2010-07-01 2012-01-05 Shantha Totada R New methods of treating dry eye syndrome
US20120010727A1 (en) 2010-07-06 2012-01-12 AFcell Medical Amnion and chorion constructs and uses thereof in sport injury surgeries
US20120010708A1 (en) 2010-07-08 2012-01-12 AFcell Medical Amnion and chorion replacement cover and uses thereof in surgical repair of muscles
US20120020933A1 (en) 2010-07-22 2012-01-26 AFcell Medical Method of nerve repair with amnion and chorion constructs
US20120035743A1 (en) 2010-08-03 2012-02-09 AFcell Medical Amnion and chorion constructs and uses thereof in minimally invasive surgeries
US20120035744A1 (en) 2010-08-04 2012-02-09 AFcell Medical Amnion and chorion constructs and uses thereof in joint repair
TWI603739B (zh) 2010-11-11 2017-11-01 艾伯維生物技術有限責任公司 具有增進高濃度之抗－ＴＮＦα抗體之液體調配物
AU2012217982B2 (en) 2011-02-14 2016-05-12 Mimedx Group Inc. Tissue grafts modified with a cross-linking agent and method of making and using the same
KR20210104178A (ko) 2011-02-14 2021-08-24 미메딕스 그룹 인크. 바르톤 젤리로 이루어진 라미네이트된 조직 이식편 및 그것의 제조 및 사용 방법
EP3744336B1 (en) 2011-02-14 2025-01-01 MiMedx Group, Inc. Micronized placental tissue compositions and methods for making and using the same
US9526770B2 (en) 2011-04-28 2016-12-27 Tissuetech, Inc. Methods of modulating bone remodeling
DK2714059T3 (en) 2011-06-01 2019-01-21 Celularity Inc TREATMENT OF PAIN WHEN USING PLACENT STAM CELLS
US9682044B2 (en) 2011-06-10 2017-06-20 Tissuetech, Inc. Methods of processing fetal support tissues, fetal support tissue powder products, and uses thereof
US9931423B2 (en) 2011-08-26 2018-04-03 Tissuetech, Inc. Methods of sterilizing fetal support tissues
CA2848397C (en) 2011-09-14 2022-04-26 Forsight Vision5, Inc. Ocular insert apparatus and methods
US8932805B1 (en) 2011-10-31 2015-01-13 BioDlogics, LLC Birth tissue material and method of preparation
US9205150B2 (en) 2011-12-05 2015-12-08 Incept, Llc Medical organogel processes and compositions
US9162011B2 (en) 2011-12-19 2015-10-20 Allosource Flowable matrix compositions and methods
DK3321355T3 (da) 2011-12-30 2021-11-08 Amit Patel Fremgangsmåder og sammensætninger til klinisk afledning af en allogen celle og terapeutiske anvendelser
US9510972B2 (en) 2012-01-04 2016-12-06 Sight Sciences, Inc. Dry eye treatment systems
US9416410B2 (en) 2012-02-14 2016-08-16 Genetics Development Corporation Cutoff point delta Ct. method for HER2 PCR testing in breast cancer
US20130211504A1 (en) 2012-02-14 2013-08-15 AFcell Medical Method of using amnion allograft in heart valve repair surgery
US8961617B2 (en) 2012-03-08 2015-02-24 Liventa Bioscience, Inc. Amnion and chorion constructs and uses thereof in abdominal surgery
US20130236506A1 (en) 2012-03-08 2013-09-12 AFcell Medical Amnion and chorion constructs and uses thereof in ob-gyn surgery
US20130289724A1 (en) 2012-04-25 2013-10-31 AFcell Medical Amnion and chorion wound dressing and uses thereof
US9295753B1 (en) 2012-07-02 2016-03-29 Celso Tello Amniotic membrane preparation and device for use as a lens or as a dressing for promoting healing
ES2846789T3 (es) 2012-07-11 2021-07-29 Tissuetech Inc Composiciones que contienen complejos HC-HA/PTX3 y métodos de uso de los mismos
CA2881010A1 (en) 2012-08-06 2014-02-13 Baylor College Of Medicine Therapeutics dispensing device and methods of making same
US9943551B2 (en) 2012-08-15 2018-04-17 Mimedx Group, Inc. Tissue grafts composed of micronized placental tissue and methods of making and using the same
WO2014028657A1 (en) 2012-08-15 2014-02-20 Mimedx Group, Inc Reinforced placental tissue grafts and methods of making and using the same
US11338063B2 (en) 2012-08-15 2022-05-24 Mimedx Group, Inc. Placental tissue grafts modified with a cross-linking agent and methods of making and using the same
US8904664B2 (en) 2012-08-15 2014-12-09 Mimedx Group, Inc. Dehydration device and methods for drying biological materials
US20140186461A1 (en) 2012-09-10 2014-07-03 Alpha Tissue, Inc. Human Amniotic Membrane Lyophilized Grafts
US20140106447A1 (en) 2012-10-12 2014-04-17 Mimedx Group, Inc. Compositions and methods for recruiting stem cells
US9180145B2 (en) 2012-10-12 2015-11-10 Mimedx Group, Inc. Compositions and methods for recruiting and localizing stem cells
WO2014066775A1 (en) 2012-10-26 2014-05-01 Forsight Vision5, Inc. Ophthalmic system for sustained release of drug to eye
US10517931B2 (en) 2013-01-17 2019-12-31 Mimedx Group, Inc. Non-surgical, localized delivery of compositions for placental growth factors
US9655948B1 (en) 2013-01-17 2017-05-23 Mimedx Group, Inc. Non-surgical, localized delivery of compositions for placental growth factors
US9827293B2 (en) 2013-01-17 2017-11-28 Mimedx Group, Inc. Non-surgical, localized delivery of compositions for placental growth factors
WO2014113733A1 (en) 2013-01-18 2014-07-24 Mimedx Group, Inc. Methods for treating cardiac conditions
US9498327B1 (en) 2013-03-05 2016-11-22 Biodlogics Llc Repair of tympanic membrane using human birth tissue material
WO2014143990A1 (en) 2013-03-15 2014-09-18 NuTech Medical, Inc. Preparations derived from placental materials of making and using same
US9795639B1 (en) 2013-03-16 2017-10-24 BioDlogics, LLC Methods for the treatment of erectile dysfunction by human birth tissue material compostion
EP2978406A1 (en) 2013-03-27 2016-02-03 Forsight Vision5, Inc. Bimatoprost ocular silicone inserts and methods of use thereof
HK1221402A1 (zh) 2013-04-02 2017-06-02 University Of Florida Research Foundation, Inc. 用於诱导并调节血管生成的组合物和方法以及用於鉴别血管生成调节剂的方法和实验
JP2016529070A (ja) 2013-09-10 2016-09-23 ミメディクス グループ インコーポレイテッド 成形胎盤組成物の美容的使用
US20160326487A1 (en) 2014-01-08 2016-11-10 Samsung Life Public Welfare Foundation Stem Cells Derived from Pure Chorionic Trophoblast Layer and Cell Therapy Comprising Same
JP7464348B2 (ja) 2014-01-17 2024-04-09 ミメディクス グループ インコーポレイテッド 血管新生を誘導する方法
US9814746B2 (en) 2014-06-15 2017-11-14 Amnio Technology Llc Method of treatment utilizing an acellular amnion derived therapeutic composition
US9132156B1 (en) 2014-06-15 2015-09-15 Amnio Technology Llc Acellular amnion derived therapeutic compositions
WO2015175776A1 (en) 2014-05-14 2015-11-19 NuTech Medical, Inc. Placental membrane preparations and methods of making and using same for regenerating cartilage and spinal intervertebral discs
WO2015179711A1 (en) 2014-05-21 2015-11-26 Mimedx Group, Inc. Micronized wharton's jelly
TW201603818A (zh) 2014-06-03 2016-02-01 組織科技股份有限公司 組成物及方法
EP3167049A4 (en) 2014-07-08 2017-11-29 MIMEDX Group Inc. Micronized wharton's jelly
TW201625229A (zh) 2014-07-14 2016-07-16 組織科技股份有限公司 用於治療玫瑰斑之組成物及方法
RU2714236C2 (ru) 2014-08-14 2020-02-13 Авита Интернэшнл Лтд. Композиции стволовых клеток и способы получения стволовых клеток для применения в терапии
WO2016040385A1 (en) 2014-09-09 2016-03-17 Mimedx Group, Inc. Micronized placental tissue compositions with optional sealant and methods of making and using the same
US9913466B2 (en) 2014-09-10 2018-03-13 Healthbanks Biotech Co. Ltd. Cryopreservation of umbilical cord tissue strips for cord tissue-derived stem cells
JP2017533917A (ja) 2014-11-05 2017-11-16 ティッシュテック，インク． 神経成長および再生を促進するための組成物および方法
US9395557B2 (en) 2014-11-12 2016-07-19 Vance M. Thompson Partial corneal conjunctival contact lens
GB2532499A (en) 2014-11-21 2016-05-25 Virgin Health Bank Qstp-Llc Improvements in tissue processing
US9694109B1 (en) 2015-01-06 2017-07-04 Brahm Holdings, Llc Nanoparticle-containing placental constructs and methods of use
US20160243288A1 (en) 2015-02-23 2016-08-25 Tissuetech, Inc. Apparatuses and methods for treating ophthalmic diseases and disorders
US10342831B2 (en) 2015-05-20 2019-07-09 Tissuetech, Inc. Composition and methods for preventing the proliferation and epithelial-mesenchymal transition of epithelial cells
KR20160140492A (ko) 2015-05-28 2016-12-07 (주)차바이오텍 향상된 산후 부착형 세포 및 그의 제조 방법
WO2017096616A1 (zh) 2015-12-11 2017-06-15 郭镭 一种无血清培养基及其制备方法和用途
WO2017096617A1 (zh) 2015-12-11 2017-06-15 郭镭 一种用于分步培养hUC-MSC的试剂盒及采用所述试剂盒获得的hUC-MSC
WO2017096615A1 (zh) 2015-12-11 2017-06-15 郭镭 一种从脐带华通氏胶组织中分离提取hUC-MSC的方法
TW201733600A (zh) 2016-01-29 2017-10-01 帝聖工業公司 胎兒扶持組織物及使用方法
US10993969B2 (en) 2016-02-05 2021-05-04 Gary M. Petrucci Methods and materials for treating nerve injuries and neurological disorders
US20170354692A1 (en) 2016-06-13 2017-12-14 MAM Holdings of West Florida, L.L.C. Amniotic fluid formulation for treatment of lung disorders
EP3474869B1 (en) 2016-06-24 2025-04-09 Osiris Therapeutics, Inc. Human tissue derived compositions and uses thereof
US20180110900A1 (en) 2016-08-21 2018-04-26 Michael S. Korenfeld Therapeutic Applications of Honey and Amniotic Membrane for the Treatment of Disease
IL264536B2 (en) 2016-08-24 2023-09-01 Arthrex Inc Use of tissue for injury repair
US20180059109A1 (en) 2016-08-31 2018-03-01 Meridigen Biotech Co., Ltd. Method of distinguishing mesenchymal stem cells and method of determining purity of mesenchymal stem cells
TWI773693B (zh) 2016-10-05 2022-08-11 新加坡商細胞研究私人有限公司 從臍帶的羊膜分離間質幹細胞的方法、從臍帶的羊膜分離的間質幹細胞群以及用於從臍帶的羊膜分離間質幹細胞的細胞培養基
US10745664B2 (en) 2016-10-28 2020-08-18 Reelabs Private Limited, a Company Incorporated Under Provisions of The Companies Act 1956 Method of progenitor cell isolation from different organs by natural destruction of extracellular matrix
WO2018085852A1 (en) 2016-11-07 2018-05-11 Ise Professional Testing & Consulting Services, Inc. Decellularized biomaterial from mammalian tissue
US20180163177A1 (en) 2016-12-11 2018-06-14 Healthbanks Biotech Co. Ltd. Serum-free culture medium and method for expanding hematopoietic stem cells
JP6557717B2 (ja) 2016-12-23 2019-08-07 インスコビー・インコーポレイテッドＩｎｓｃｏｂｅｅ，Ｉｎｃ． 生体植立用インプラント及びその製造方法
US20180177989A1 (en) 2016-12-28 2018-06-28 Regen Medical Inc. Vaginal rejuvenation methods and devices
CN108324736A (zh) 2017-01-18 2018-07-27 傅毓秀 脐带间质干细胞用于治疗肺纤维化的用途
US20180264049A1 (en) 2017-03-20 2018-09-20 Batu Biologics, Inc. Immunotherapy of Aberrant Ocular Angiogenesis by Placental Vaccination
US20180271914A1 (en) 2017-03-21 2018-09-27 Noveome Biotherapeutics, Inc. Methods for Reducing the Extent of Light-induced Tissue Inflammation and Injury
US20180311408A1 (en) 2017-05-01 2018-11-01 Trojan Medical Solutions, LLC Amnion based conduit tissue
US20180346874A1 (en) 2017-06-02 2018-12-06 Janssen Biotech, Inc. Methods of obtaining cells from human postpartum umbilical cord arterial tissue
WO2018220490A1 (en) 2017-06-02 2018-12-06 Janssen Biotech, Inc. Method of modulating müller glia cells
TW201932126A (zh) 2017-11-03 2019-08-16 美商健生生物科技公司 抑制血管生成之方法
US10575516B2 (en) 2017-11-14 2020-03-03 Cook Biotech Incorporated Preserved tissue products and related methods

Also Published As

Publication number Publication date
US9750771B2 (en) 2017-09-05
EP2664337B1 (en) 2019-08-14
DK1933852T3 (en) 2019-03-25
CA2949643C (en) 2018-05-15
WO2007038686A3 (en) 2007-09-13
US10272119B2 (en) 2019-04-30
HK1213499A1 (zh) 2016-07-08
US20070071740A1 (en) 2007-03-29
US20120269880A1 (en) 2012-10-25
US20180193387A1 (en) 2018-07-12
US20130280344A1 (en) 2013-10-24
US20160129050A1 (en) 2016-05-12
US9161955B2 (en) 2015-10-20
JP5505760B2 (ja) 2014-05-28
US20130195993A1 (en) 2013-08-01
US20120328690A1 (en) 2012-12-27
US20120207848A1 (en) 2012-08-16
US8182840B2 (en) 2012-05-22
CN104873956A (zh) 2015-09-02
WO2007038686A2 (en) 2007-04-05
US20070231401A1 (en) 2007-10-04
CA2949643A1 (en) 2007-04-05
JP2009510091A (ja) 2009-03-12
US10632155B2 (en) 2020-04-28
US8460714B2 (en) 2013-06-11
CN101316602A (zh) 2008-12-03
JP2014098021A (ja) 2014-05-29
US20160151424A1 (en) 2016-06-02
EP1933852A4 (en) 2010-06-09
US9956252B2 (en) 2018-05-01
CN101316602B (zh) 2015-06-03
US20160129049A1 (en) 2016-05-12
US9198939B2 (en) 2015-12-01
US8182841B2 (en) 2012-05-22
AU2006294581A1 (en) 2007-04-05
CN104873956B (zh) 2019-04-23
CA2623940A1 (en) 2007-04-05
US20170326182A1 (en) 2017-11-16
US8440235B2 (en) 2013-05-14
US8455009B2 (en) 2013-06-04
EP2664337A1 (en) 2013-11-20
US9161956B2 (en) 2015-10-20
US20080299087A1 (en) 2008-12-04
ES2713062T3 (es) 2019-05-17
EP1933852B1 (en) 2018-12-19
US8153162B2 (en) 2012-04-10
CA2623940C (en) 2017-01-10
AU2006294581B2 (en) 2011-11-03
JP5900985B2 (ja) 2016-04-06
US20130195994A1 (en) 2013-08-01
US9724370B2 (en) 2017-08-08
EP1933852A2 (en) 2008-06-25

Similar Documents

Publication Publication Date Title
CA2949643C (en) Amniotic membrane preparations and purified compositions and methods of use
US9750772B2 (en) Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
HK1213499B (en) Amniotic membrane preparations and purified compositions and methods of use

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20180326

FZDE Discontinued

Effective date: 20210831