CA2762011C - Compositions and methods for control of insect infestations in plants - Google Patents

Compositions and methods for control of insect infestations in plants Download PDF

Info

Publication number
CA2762011C
CA2762011C CA2762011A CA2762011A CA2762011C CA 2762011 C CA2762011 C CA 2762011C CA 2762011 A CA2762011 A CA 2762011A CA 2762011 A CA2762011 A CA 2762011A CA 2762011 C CA2762011 C CA 2762011C
Authority
CA
Canada
Prior art keywords
pest
sequence
seq
dsrna
plant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2762011A
Other languages
English (en)
French (fr)
Other versions
CA2762011A1 (en
Inventor
James A. Baum
Larry A. Gilbertson
David K. Kovalic
Thomas J. Larosa
Maolong Lu
Tichafa R. I. Munyikwa
James K. Roberts
Wei Wu
Bei Zhang
Original Assignee
Monsanto Technology LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35394619&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2762011(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Monsanto Technology LLC filed Critical Monsanto Technology LLC
Publication of CA2762011A1 publication Critical patent/CA2762011A1/en
Application granted granted Critical
Publication of CA2762011C publication Critical patent/CA2762011C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/60—Isolated nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
    • C12N15/8275—Glyphosate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8285—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for nematode resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Virology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Catching Or Destruction (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
CA2762011A 2004-04-09 2005-04-08 Compositions and methods for control of insect infestations in plants Expired - Lifetime CA2762011C (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US56084204P 2004-04-09 2004-04-09
US60/560,842 2004-04-09
US56563204P 2004-04-27 2004-04-27
US60/565,632 2004-04-27
US57906204P 2004-06-11 2004-06-11
US60/579,062 2004-06-11
US60342104P 2004-08-20 2004-08-20
US60/603,421 2004-08-20
US61726104P 2004-10-11 2004-10-11
US60/617,261 2004-10-11
US66917505P 2005-04-07 2005-04-07
US60/669,175 2005-04-07
CA2562022A CA2562022C (en) 2004-04-09 2005-04-08 Compositions and methods for control of insect infestations in plants

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2562022A Division CA2562022C (en) 2004-04-09 2005-04-08 Compositions and methods for control of insect infestations in plants

Publications (2)

Publication Number Publication Date
CA2762011A1 CA2762011A1 (en) 2005-11-24
CA2762011C true CA2762011C (en) 2019-05-07

Family

ID=35394619

Family Applications (3)

Application Number Title Priority Date Filing Date
CA2762011A Expired - Lifetime CA2762011C (en) 2004-04-09 2005-04-08 Compositions and methods for control of insect infestations in plants
CA2562022A Expired - Lifetime CA2562022C (en) 2004-04-09 2005-04-08 Compositions and methods for control of insect infestations in plants
CA2693280A Expired - Lifetime CA2693280C (en) 2004-04-09 2005-04-08 Compositions and methods for control of insect infestations in plants

Family Applications After (2)

Application Number Title Priority Date Filing Date
CA2562022A Expired - Lifetime CA2562022C (en) 2004-04-09 2005-04-08 Compositions and methods for control of insect infestations in plants
CA2693280A Expired - Lifetime CA2693280C (en) 2004-04-09 2005-04-08 Compositions and methods for control of insect infestations in plants

Country Status (14)

Country Link
US (10) US20060021087A1 (enExample)
EP (4) EP1818405B2 (enExample)
CN (2) CN102524294B (enExample)
AR (1) AR048685A1 (enExample)
AU (2) AU2005244258B2 (enExample)
BR (1) BRPI0509743A (enExample)
CA (3) CA2762011C (enExample)
EC (1) ECSP066908A (enExample)
ES (2) ES2547381T3 (enExample)
MX (1) MXPA06011694A (enExample)
PL (2) PL1818405T3 (enExample)
PT (2) PT1818405E (enExample)
WO (1) WO2005110068A2 (enExample)
ZA (1) ZA200607995B (enExample)

Families Citing this family (230)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090044297A1 (en) * 1999-05-06 2009-02-12 Andersen Scott E Transgenic plants with enhanced agronomic traits
US9322031B2 (en) 1999-05-06 2016-04-26 Monsanto Technology Llc Transgenic plants with enhanced agronomic traits
US20090241217A9 (en) * 2001-05-22 2009-09-24 Jingrui Wu Yield-improved transgenic plants
US7612194B2 (en) * 2001-07-24 2009-11-03 Monsanto Technology Llc Nucleic acid sequences from Diabrotica virgifera virgifera LeConte and uses thereof
US20090183270A1 (en) 2002-10-02 2009-07-16 Adams Thomas R Transgenic plants with enhanced agronomic traits
US20090049573A1 (en) * 2002-10-02 2009-02-19 Dotson Stanton B Transgenic plants with enhanced agronomic traits
PL1656449T3 (pl) 2003-08-21 2009-08-31 Monsanto Technology Llc Desaturazy kwasów tłuszczowych z Primula
ATE526407T1 (de) * 2003-11-17 2011-10-15 Commw Scient Ind Res Org Insektenresistenz durch inhibierung von genexpression
PT1818405E (pt) 2004-04-09 2015-10-20 Monsanto Technology Llc Composições e métodos para o controlo de infestações de plantas por insectos
US20160230185A1 (en) 2013-03-14 2016-08-11 Monsanto Technology Llc Compositions and methods for controlling diabrotica
US20060200878A1 (en) 2004-12-21 2006-09-07 Linda Lutfiyya Recombinant DNA constructs and methods for controlling gene expression
US8404927B2 (en) * 2004-12-21 2013-03-26 Monsanto Technology Llc Double-stranded RNA stabilized in planta
US8314290B2 (en) 2004-12-21 2012-11-20 Monsanto Technology Llc Temporal regulation of gene expression by MicroRNAs
EP1907546A2 (en) * 2005-05-31 2008-04-09 Devgen N.V. Rnai for control of insects and arachnids
PT2270181E (pt) 2005-09-16 2016-01-26 Devgen Nv Arncd como agente de controlo de insetos
SG166097A1 (en) * 2005-09-16 2010-11-29 Monsanto Technology Llc Methods for genetic control of insect infestations in plants and compositions thereof
US8853489B2 (en) 2005-09-16 2014-10-07 Devgen Nv Transgenic plant-based methods for plant pests using RNAi
WO2007047016A2 (en) 2005-10-13 2007-04-26 Monsanto Technology, Llc Methods for producing hybrid seed
US8906876B2 (en) 2006-01-12 2014-12-09 Devgen Nv Methods for controlling pests using RNAi
EP1971688B1 (en) * 2006-01-12 2012-03-14 Devgen NV Dsrna as insect control agent
CA2633576A1 (en) * 2006-01-12 2007-07-19 Devgen N.V. Dsrna as insect control agent
CN101421406B (zh) 2006-02-13 2016-08-31 孟山都技术有限公司 用于产生改变的种子油组成的核酸构建体和方法
CN101384721A (zh) 2006-02-13 2009-03-11 孟山都技术有限公司 选择和稳定dsRNA构建体
CL2007001851A1 (es) * 2006-06-23 2008-01-18 Monsanto Technology Llc Socedad Anonima Organizada Bajo Las Leyes Del Estado De Delaware Segmento de adn de planta que comprende una secuencia recombinante de un factor de transcripcion nuclear y (nf-yb), celula vegetal que lo comprende y metodo para elaborar semillas que comprende seleccionar plantas que comprendan dicho adn.
CN101600798A (zh) 2006-08-31 2009-12-09 孟山都技术有限公司 相位型小rna
EP3199646A1 (en) 2006-10-12 2017-08-02 Monsanto Technology LLC Plant micrornas and methods of use thereof
CN101195821A (zh) 2006-12-04 2008-06-11 中国科学院上海生命科学研究院 利用RNAi技术改良植物抗虫性的方法
US8410334B2 (en) * 2007-02-20 2013-04-02 Monsanto Technology Llc Invertebrate microRNAs
US8609936B2 (en) 2007-04-27 2013-12-17 Monsanto Technology Llc Hemipteran-and coleopteran active toxin proteins from Bacillus thuringiensis
US20100180352A1 (en) * 2007-06-15 2010-07-15 Basf Plant Science Gmbh Compositions and Methods of Using RNA Interference for Control of Nematodes
US8097712B2 (en) 2007-11-07 2012-01-17 Beelogics Inc. Compositions for conferring tolerance to viral disease in social insects, and the use thereof
US20090188008A1 (en) * 2008-01-17 2009-07-23 Pioneer Hi-Bred International, Inc. Compositions and methods for the suppression of target polynucleotides
US8367895B2 (en) 2008-01-17 2013-02-05 Pioneer Hi-Bred International, Inc. Compositions and methods for the suppression of target polynucleotides from the family aphididae
US8809625B2 (en) 2008-01-17 2014-08-19 Pioneer Hi-Bred International, Inc. Compositions and methods for the suppression of target polynucleotides from Lygus
US8847013B2 (en) * 2008-01-17 2014-09-30 Pioneer Hi Bred International Inc Compositions and methods for the suppression of target polynucleotides from lepidoptera
WO2009103808A2 (en) * 2008-02-20 2009-08-27 Devgen N.V. Methods and compositions for increasing rna interference
US8003335B2 (en) 2008-04-30 2011-08-23 Universite Paris-SUD11 Levels of APRIL in serum and use in diagnostic methods
US9040774B2 (en) 2008-07-01 2015-05-26 Monsanto Technology Llc Recombinant DNA constructs encoding ribonuclease cleavage blockers and methods for modulating expression of a target gene
AR073237A1 (es) 2008-08-29 2010-10-20 Monsanto Technology Llc Proteinas de bacillus thuringiensis que son toxinas activas contra hemipteros y coleopteros
US11408003B2 (en) * 2008-12-18 2022-08-09 Dicerna Pharmaceuticals, Inc. Extended dicer substrate agents and methods for the specific inhibition of gene expression
US20100257634A1 (en) * 2009-04-03 2010-10-07 Venganza Inc. Bioassay for gene silencing constructs
WO2010141294A1 (en) * 2009-06-01 2010-12-09 North Carolina State University Insecticidal target genes identified from bug whole body and digestive system transcriptomes
US20110054007A1 (en) * 2009-08-28 2011-03-03 E.I. Du Pont De Nemours And Company Compositions and methods to control insect pests
JP5396353B2 (ja) * 2009-09-17 2014-01-22 日本碍子株式会社 静電チャック及びその製法
EP2730657B1 (en) 2009-09-29 2017-07-12 Temasek Life Sciences Laboratory Limited Control of pests in plants by VIGS
US8962584B2 (en) * 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
US20110165561A1 (en) 2009-12-31 2011-07-07 Pioneer Hi-Bred International, Inc. Direct and continuous root alone or root/shoot production from transgenic events derived from green regenerative tissues and its applications
US20110183369A1 (en) * 2010-01-28 2011-07-28 Monsanto Technology Llc Plant infesting systems and methods
US8735560B1 (en) 2010-03-02 2014-05-27 Monsanto Technology Llc Multiple domain lepidopteran active toxin proteins
CN102948425B (zh) * 2010-03-05 2014-10-22 广州市锐博生物科技有限公司 一种生物农药和昆虫防治方法
PL2545182T4 (pl) 2010-03-08 2017-11-30 Monsanto Technology Llc Cząsteczki polinukeotydu do regulacji genów w roślinach
JP5732687B2 (ja) * 2010-03-19 2015-06-10 エルジー ケム． エルティーディ． ポーチ型ケース及びこれを含む電池パック
US8530440B2 (en) * 2010-05-03 2013-09-10 Board Of Regents Of The University Of Nebraska dsRNA delivery composition and methods of use
US8872001B2 (en) 2010-06-04 2014-10-28 Pioneer Hi Bred International Inc Compositions and methods for insecticidal control of stinkbugs
AU2011305775C1 (en) 2010-09-20 2016-04-21 Wisconsin Alumni Research Foundation Mosquitocidal Xenorhabdus, lipopeptide and methods
CN103201385A (zh) 2010-10-27 2013-07-10 德福根有限公司 下调昆虫害虫中的基因表达
PH12013501410A1 (en) * 2010-12-30 2013-08-28 Dow Agrosciences Llc Nucleic acid molecules that target the rho1 small gtp-binding protein and confer resistance to coleopteran pests
AU2011351969A1 (en) * 2010-12-30 2013-07-25 Dow Agrosciences Llc Nucleic acid molecules that target the RHO1 small GTP-binding protein and confer resistance to coleopteran pests
KR20130130804A (ko) * 2010-12-30 2013-12-02 다우 아그로사이언시즈 엘엘씨 공포 ａｔｐａｓｅ ｃ 서브유닛을 표적화하고 딱정벌레목 해충에 대한 저항성을 부여하는 핵산 분자
US9693555B2 (en) * 2011-03-18 2017-07-04 Shanghai Institutes For Biological Sciences, Chinese Academy Of Sciences Insect-combating preparation and method based on RNAi technology
EP2699685B1 (en) * 2011-04-20 2018-03-14 Devgen NV Down-regulating gene expression in insect pests
US8841272B2 (en) * 2011-05-31 2014-09-23 Kansas State University Research Foundation Double-stranded RNA-based nanoparticles for insect gene silencing
CN102866220B (zh) * 2011-07-08 2014-07-23 中国科学院大连化学物理研究所 一种基于化学衍生的飞蝗血淋巴代谢物的检测方法
BR112014001398A2 (pt) * 2011-07-18 2020-12-01 Devgen Nv regulação negativa da expressão genética em pragas de insetos
CA2842709A1 (en) * 2011-08-16 2013-02-21 Syngenta Participations Ag Methods and compositions for introduction of exogenous dsrna into plant cells
CA2848680C (en) 2011-09-13 2020-05-19 Monsanto Technology Llc Methods and compositions for weed control
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
UA115535C2 (uk) 2011-09-13 2017-11-27 Монсанто Текнолоджи Ллс Спосіб та композиція для боротьби з бур'янами (варіанти)
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
US9840715B1 (en) 2011-09-13 2017-12-12 Monsanto Technology Llc Methods and compositions for delaying senescence and improving disease tolerance and yield in plants
EP2755988B1 (en) 2011-09-13 2018-08-22 Monsanto Technology LLC Methods and compositions for weed control
MX377067B (es) 2011-09-13 2025-03-07 Monsanto Technology Llc Métodos y composiciones para el control de malezas.
US9920326B1 (en) 2011-09-14 2018-03-20 Monsanto Technology Llc Methods and compositions for increasing invertase activity in plants
WO2013052908A2 (en) * 2011-10-06 2013-04-11 Dow Agrosciences Llc Nucleic acid molecules that target rps6 and confer resistance to coleopteran pests
TW201321509A (zh) * 2011-10-06 2013-06-01 Dow Agrosciences Llc 靶定ｐｐ１－８７ｂ且賦予對鞘翅目害蟲抗性之核酸分子
US9770035B2 (en) * 2011-10-06 2017-09-26 Dow Agrosciences Llc Nucleic acid molecules that target RPA70 and confer resistance to coleopteran pests
GB201202119D0 (en) * 2012-02-08 2012-03-21 Univ Swansea Pest and pathogen control
IN2014DN08695A (enExample) 2012-04-06 2015-05-22 Monsanto Technology Llc
UY34752A (es) * 2012-04-20 2013-11-29 Futuragene Israel Ltd Agentes para el control de la chinche del eucalipto
WO2013163085A2 (en) * 2012-04-23 2013-10-31 Futuragene Israel Ltd. Glycaspis brimblecombei control agents
ES2903185T3 (es) 2012-05-08 2022-03-31 Monsanto Technology Llc Evento de maíz MON 87411
AR091143A1 (es) 2012-05-24 2015-01-14 Seeds Ltd Ab Composiciones y metodos para silenciar la expresion genetica
MX370669B (es) * 2012-06-22 2019-12-19 Syngenta Participations Ag Control biológico de plagas de coleópteros.
EP2897453B1 (en) * 2012-09-20 2018-03-28 E. I. du Pont de Nemours and Company Management of corn rootworm and other insect pests
US10004236B2 (en) * 2012-09-24 2018-06-26 Lincoln University Biocontrol compositions
MX364070B (es) 2012-10-18 2019-04-10 Monsanto Technology Llc Métodos y composiciones para el control de plagas vegetales.
DE102012110664A1 (de) * 2012-11-07 2014-05-08 Henkel Ag & Co. Kgaa In Beschichtungsmitteln, Haftvermittlern oder Klebstoffen für oxidische Oberflächen einsetzbare Peptide
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
CN105358695B (zh) 2013-01-01 2019-07-12 A.B.种子有限公司 将dsRNA引入植物种子以调节基因表达的方法
US10000767B2 (en) 2013-01-28 2018-06-19 Monsanto Technology Llc Methods and compositions for plant pest control
UA121846C2 (uk) 2013-03-13 2020-08-10 Монсанто Текнолоджи Ллс Спосіб та гербіцидна композиція для контролю видів рослини роду lolium
EP2971185A4 (en) 2013-03-13 2017-03-08 Monsanto Technology LLC Methods and compositions for weed control
EA029279B1 (ru) * 2013-03-14 2018-03-30 Пайонир Хай-Бред Интернэшнл Инк. Композиции и способы контроля насекомых-вредителей
US20140283211A1 (en) 2013-03-14 2014-09-18 Monsanto Technology Llc Methods and Compositions for Plant Pest Control
US9920316B2 (en) 2013-03-14 2018-03-20 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
BR112015023709A2 (pt) 2013-03-15 2017-07-18 Pioneer Hi Bred Int polipeptídeo phi-4, polinucleotídeo, composição, método para inibir o crescimento, método para controlar uma população, planta, semente, cassete de expressão, método para expressar em uma planta um polinucleotídeo, método para proteger uma planta, proteína de fusão
US9365863B2 (en) 2013-05-08 2016-06-14 Monsanto Technology Llc Compositions and methods for deploying a transgenic refuge seed blend
MX359191B (es) 2013-07-19 2018-09-18 Monsanto Technology Llc Composiciones y métodos para controlar leptinotarsa.
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
BR112016003225B1 (pt) 2013-08-16 2022-10-25 Pioneer Hi-Bred International, Inc. Polipeptídeo pip-47, polipeptídeo pip-47 quimérico, composição, proteína de fusão, método para controlar uma população de inseto-praga, método para inibir o crescimento ou matar um inseto-praga, construto de dna, polinucleotídeo isolado, cassete de expressão, método de obtenção de uma planta transgênica e método para controlar infestação de inseto
BR122020001770B1 (pt) 2013-09-13 2022-11-29 Pioneer Hi-Bred International, Inc Construto de dna, método de obtenção de planta transgênica, proteína de fusão, método para controlar uma população de praga de inseto, método para inibir o crescimento ou matar uma praga de inseto
WO2015042556A1 (en) 2013-09-23 2015-03-26 Georgia Tech Research Corporation Targeting non-coding rna for rna interference
UY35817A (es) 2013-11-04 2015-05-29 Us Agriculture ?composiciones y métodos para controlar infestaciones de plagas y parásitos de los artrópodos?.
CN104630275A (zh) * 2013-11-12 2015-05-20 中国科学院上海生命科学研究院 一种通过灌溉防治害虫的RNAi技术及其应用
HUE045100T2 (hu) 2013-12-04 2019-12-30 Stoller Ets Eljárás a diformil-urea kukoricára juttatására
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
BR102014031844A2 (pt) * 2013-12-20 2015-10-06 Dow Agrosciences Llc ras oposto (rop) e moléculas de ácido nucleico relacionadas que conferem resistência a pragas de coleópteros e hemípteros
EP3116303B1 (en) 2014-01-15 2020-07-22 Monsanto Technology LLC Methods and compositions for weed control using epsps polynucleotides
US10227608B2 (en) 2014-02-07 2019-03-12 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
EP3104709A4 (en) * 2014-02-10 2017-10-25 Ibex Bionomics LLC Bio-derived compositions for use in agriculture
MX366975B (es) 2014-03-12 2019-08-01 Univ Sydney Produccion de arn en plantas superiores.
CN103828721B (zh) * 2014-03-20 2016-03-02 北京农学院 地衣芽孢杆菌在促进蓝莓组培苗生根或生长中的应用
WO2015148976A1 (en) 2014-03-28 2015-10-01 Monsanto Technology Llc Pesticidal toxin proteins active against coleopteran insects
EP3420809A1 (en) 2014-04-01 2019-01-02 Monsanto Technology LLC Compositions and methods for controlling insect pests
UY36113A (es) * 2014-05-07 2015-10-30 Dow Agrosciences Llc Moléculas de ácido nucleico dre4 que confieren resistencia a plagas de coleópteros
AU2015280252A1 (en) 2014-06-23 2017-01-12 Monsanto Technology Llc Compositions and methods for regulating gene expression via RNA interference
WO2015200539A1 (en) 2014-06-25 2015-12-30 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
CN104170557B (zh) * 2014-07-24 2016-06-29 四川农业大学 一种促进中国樱桃种子快速高效萌发成苗的方法
WO2016018887A1 (en) 2014-07-29 2016-02-04 Monsanto Technology Llc Compositions and methods for controlling insect pests
US20170247719A1 (en) * 2014-09-17 2017-08-31 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
WO2016060911A1 (en) * 2014-10-13 2016-04-21 Dow Agrosciences Llc Copi coatomer gamma subunit nucleic acid molecules that confer resistance to coleopteran and hemipteran pests
CN107148426A (zh) * 2014-10-13 2017-09-08 美国陶氏益农公司 赋予鞘翅目和半翅目害虫抗性的copi外被体alpha亚单位核酸分子
AU2015332370B2 (en) 2014-10-16 2019-09-19 Monsanto Technology Llc Lepidopteran-active Cry1Da1 amino acid sequence variant proteins
US10487123B2 (en) 2014-10-16 2019-11-26 Monsanto Technology Llc Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests
UA126192C2 (uk) 2014-10-16 2022-08-31 Піонір Хай-Бред Інтернешнл, Інк. Інсектицидний білок та спосіб його застосування
WO2016061392A1 (en) 2014-10-16 2016-04-21 Monsanto Technology Llc Proteins toxic or inhibitory to lepidopteran insects
CU24551B1 (es) 2014-10-16 2021-11-04 Monsanto Technology Llc Proteínas de bacillus thuringiensis quiméricas insecticidas tóxicas o inhibidoras de plagas de lepidópteros
EP3218497A1 (en) 2014-11-12 2017-09-20 NMC Inc. Transgenic plants with engineered redox sensitive modulation of photosynthetic antenna complex pigments and methods for making the same
EP3926049A1 (en) 2014-11-20 2021-12-22 Monsanto Technology LLC Novel insect inhibitory proteins
UY36442A (es) * 2014-12-16 2016-07-29 Dow Agrosciences Llc Supresión de arni parental de gen kruppel para el control de las plagas de hemípteros
MX369475B (es) 2015-01-15 2019-11-08 Pioneer Hi Bred Int Proteinas insecticidas y metodos para sus usos.
EP3244730A4 (en) * 2015-01-16 2018-08-15 Emekatech, LLC Systems, methods and compositions for effective insect population suppression
PL3256589T3 (pl) 2015-01-22 2022-02-21 Monsanto Technology Llc Kompozycje i sposoby kontrolowania leptinotarsa
CA2977460A1 (en) * 2015-02-27 2016-09-01 E. I. Du Pont De Nemours And Company Compositions and methods to control insect pests
US10876132B2 (en) 2015-03-11 2020-12-29 Pioneer Hi-Bred International, Inc. Insecticidal combinations of PIP-72 and methods of use
CN108064233B (zh) 2015-05-19 2022-07-15 先锋国际良种公司 杀昆虫蛋白及其使用方法
KR20180012278A (ko) * 2015-05-27 2018-02-05 다우 아그로사이언시즈 엘엘씨 노린재목 해충에 대한 저항성을 부여하는 스레드(thread) 핵산 분자
EP3302053B1 (en) 2015-06-02 2021-03-17 Monsanto Technology LLC Compositions and methods for delivery of a polynucleotide into a plant
EP3302030A4 (en) 2015-06-03 2019-04-24 Monsanto Technology LLC METHOD AND COMPOSITIONS FOR INTRODUCING NUCLEIC ACIDS IN PLANTS
GB201510154D0 (en) * 2015-06-11 2015-07-29 Univ Swansea Pest control system
EP3310803A1 (en) 2015-06-16 2018-04-25 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
UA126327C2 (uk) 2015-07-30 2022-09-21 Монсанто Текнолоджі Елелсі Молекула рекомбінантної нуклеїнової кислоти, яка кодує білок, що проявляє інгібуючу активність відносно комах
CN109475096B (zh) 2015-08-06 2022-08-23 先锋国际良种公司 植物来源的杀昆虫蛋白及其使用方法
HUE056166T2 (hu) 2015-08-27 2022-01-28 Monsanto Technology Llc Új rovargátló fehérjék
BR112018005452A2 (pt) * 2015-09-25 2018-10-09 Dow Agrosciences Llc moléculas de ácido nucleico de shibire/dinamina para controle de pragas coleópteras e hemípteras
CN108135182A (zh) * 2015-10-05 2018-06-08 先正达参股股份有限公司 保存核糖核酸生物活性的方法
BR112018007396A2 (pt) 2015-10-12 2018-10-16 Droneseed Co sistemas e métodos de gestão de informação florestal aperfeiçoados por hierarquização automática de dados biométricos
US10212876B2 (en) 2015-10-12 2019-02-26 Droneseed Co. Aerial deployment planting methods and systems
AR106309A1 (es) 2015-10-12 2018-01-03 Pioneer Hi Bred Int Composición que comprende una cepa fúngica entomopatogénica para control de plagas en plantas
WO2017066041A2 (en) * 2015-10-12 2017-04-20 Dow Agrosciences Llc Wupa nucleic acid molecules that confer resistance to coleopteran and hemipteran pests
EP3371296A4 (en) * 2015-11-02 2019-06-19 Dow Agrosciences LLC RAB5-NUCLEIC ACID MOLECULES FOR THE AWARDING OF RESISTANCE TO COLEOPTERA AND HEMIPTERA PESTS
BR112018011174A2 (pt) 2015-11-30 2018-11-21 Du Pont polinucleotídeo recombinante, construto de dna, célula heteróloga, planta transgênica ou célula de planta, semente da planta transgênica, método para expressar um polinucleotídeo em uma planta e método para aprimorar a transcrição de um polinucleotídeo em uma célula hospedeira
US9856291B2 (en) * 2015-12-08 2018-01-02 Agricultural Technology Research Institute Cancer stem cell targeting peptide and use thereof
US11134675B2 (en) 2015-12-14 2021-10-05 Monsanto Technology Llc Methods and compositions for delivery of polynucleotides
CA3002995A1 (en) 2015-12-18 2017-06-22 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
AU2016371636A1 (en) 2015-12-18 2018-06-21 Dow Agrosciences Llc Ribosomal protein L40 (RPL40) nucleic acid molecules that confer resistance to coleopteran and hemipteran pests
CN105543224B (zh) 2016-01-04 2020-01-14 北京大北农科技集团股份有限公司 用于控制昆虫侵袭的核苷酸序列及其方法
US10975387B2 (en) * 2016-01-26 2021-04-13 Monsanto Technology Llc Compositions and methods for controlling insect pests
AR108085A1 (es) * 2016-04-05 2018-07-18 Dow Agrosciences Llc Moléculas de ácido nucleico fsh para el control de plagas de insectos
BR112018072417B1 (pt) 2016-05-04 2023-03-14 E. I. Du Pont De Nemours And Company Polipeptídeo inseticida recombinante, polipeptídeo quimérico, composição, polinucleotídeo recombinante, construtos de dna, métodos para obter uma planta transgênica, métodos para inibir o crescimento ou extermínio de uma praga de inseto ou população de praga, método para obter uma célula procariótica transformada, célula procariótica transformada e método para modificar geneticamente o polipeptídeo inseticida
CA3023483C (en) 2016-05-16 2024-01-16 Danisco Us Inc. Entomopathogenic products, metarhizium anisopliae or metarhizium robertsii
US20190343122A1 (en) * 2016-05-27 2019-11-14 Provivi, Inc. Improved insect control strategies utilizing pheromones and rnai
CA3022858A1 (en) 2016-06-16 2017-12-21 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
US10612037B2 (en) 2016-06-20 2020-04-07 Monsanto Technology Llc Insecticidal proteins toxic or inhibitory to hemipteran pests
CA3028377A1 (en) * 2016-06-22 2017-12-28 Dow Agrosciences Llc Cactus nucleic acid molecules to control coleopteran pests
UA127388C2 (uk) 2016-06-24 2023-08-09 Піонір Хай-Бред Інтернешнл, Інк. Регуляторний елемент рослини і спосіб його застосування
PH12018502706B1 (en) 2016-07-01 2024-05-24 Pioneer Hi Bred Int Insecticidal proteins from plants and methods for their use
WO2018013333A1 (en) 2016-07-12 2018-01-18 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
US20180023076A1 (en) * 2016-07-25 2018-01-25 The United States Of America, As Represented By The Secretary Of Agriculture Double strand rna delivery system for plant-sap-feeding insects
AR109205A1 (es) * 2016-08-05 2018-11-07 Syngenta Participations Ag Control de plagas de coleópteros utilizando moléculas de arn
AR109206A1 (es) * 2016-08-05 2018-11-07 Syngenta Participations Ag Control de plagas de coleópteros utilizando moléculas de arn
CA3036620A1 (en) * 2016-10-05 2018-04-12 Syngenta Participations Ag Methods of preserving the biological activity of ribonucleic acids
CN107058466A (zh) * 2016-10-20 2017-08-18 中国农业科学院植物保护研究所 玉米根萤叶甲特异性ss‑coi引物及检测方法和应用
WO2018084936A1 (en) 2016-11-01 2018-05-11 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
JP2020511472A (ja) * 2016-12-06 2020-04-16 ぺブル ラボ ユーエスエー インコーポレーテッド 植物病原体の生物的防除のための系および方法
CA3044404A1 (en) 2016-12-14 2018-06-21 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
MX2019007491A (es) 2016-12-22 2019-09-06 Pioneer Hi Bred Int Proteinas insecticidas y metodos para su uso.
WO2018140214A1 (en) 2017-01-24 2018-08-02 Pioneer Hi-Bred International, Inc. Nematicidal protein from pseudomonas
WO2018148001A1 (en) 2017-02-08 2018-08-16 Pioneer Hi-Bred International Inc Insecticidal combinations of plant derived insecticidal proteins and methods for their use
CA3057314A1 (en) * 2017-03-21 2018-09-27 Dow Agrosciences Llc Pre-mrna processing factor 19 (prp19) nucleic acid molecules to control insect pests
EP3618634A4 (en) * 2017-05-01 2021-07-21 Donald Danforth Plant Science Center RNA-BASED APPROACH TO PLANT PROTECTION
BR112019023628A2 (pt) 2017-05-11 2020-06-02 Pioneer Hi-Bred International, Inc. Polipeptídeo inseticida recombinante, proteína inseticida quimérica, proteína de fusão, composição agrícola, polinucleotídeo recombinante, construto de dna, planta transgênica, método para inibir o crescimento ou exterminar uma praga de inseto ou população de praga, método para controlar os danos por praga de inseto, método para controlar infestação de praga e método para melhorar o rendimento de uma cultura
AR111946A1 (es) * 2017-05-18 2019-09-04 Dow Agrosciences Llc Moléculas de ácido nucleico de proteína de reconocimiento específico de la estructura 1 (ssrp1) para controlar plagas de insectos
CN111148432B (zh) 2017-10-02 2021-11-23 先正达参股股份有限公司 工程化的杀有害生物蛋白和控制植物有害生物的方法
WO2019074598A1 (en) 2017-10-13 2019-04-18 Pioneer Hi-Bred International, Inc. VIRUS-INDUCED GENETIC SILENCING TECHNOLOGY FOR THE CONTROL OF INSECTS IN MAIZE
GB201718701D0 (en) 2017-11-13 2017-12-27 Syngenta Participations Ag Improvements in or relating to gene silencing
GB201719680D0 (en) 2017-11-27 2018-01-10 Devgen Nv Improvements in or relating to gene silencing
DK3740070T3 (da) 2018-01-18 2025-01-20 Pioneer Hi Bred Int Alginat-indkapsling af fungale mikrosklerotier
WO2019169150A1 (en) 2018-03-02 2019-09-06 Pioneer Hi-Bred International, Inc. Plant health assay
CN116410286A (zh) 2018-03-14 2023-07-11 先锋国际良种公司 来自植物的杀昆虫蛋白及其使用方法
EP3764798B1 (en) 2018-03-14 2025-12-17 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
US12054724B2 (en) 2018-04-10 2024-08-06 President And Fellows Of Harvard College AAV vectors encoding clarin-1 or GJB2 and uses thereof
US11702668B2 (en) 2018-05-22 2023-07-18 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
WO2020016892A1 (en) 2018-07-18 2020-01-23 Plantarcbio Ltd. Compositions and methods for mitigating pest infestation with rhynchophorus ferrugineus
CN119060146A (zh) 2018-08-29 2024-12-03 先锋国际良种公司 杀昆虫蛋白及其使用方法
WO2020068018A1 (en) * 2018-09-24 2020-04-02 Orta Dogu Teknik Universitesi Modified aox1 promoter variants
US11375656B2 (en) 2018-11-06 2022-07-05 Droneseed Co. Remote drone configuration systems and methods
MX2021005757A (es) 2018-11-15 2021-08-11 Quantum Si Inc Metodos y composiciones para la secuenciacion de proteinas.
US20220015372A1 (en) 2018-12-14 2022-01-20 Pioneer Hi-Bred International, Inc. Biologicals and their use in plants
CN109337884B9 (zh) * 2018-12-21 2021-10-29 中国农业科学院北京畜牧兽医研究所 一种丙酮酸激酶基因及其应用
WO2020154301A1 (en) 2019-01-22 2020-07-30 Monsanto Technology Llc Novel insect inhibitory proteins
US12258374B2 (en) 2019-02-20 2025-03-25 Syngenta Crop Protection Ag Engineered pesticidal proteins and methods of controlling plant pests
JP7659271B2 (ja) * 2019-03-28 2025-04-09 ザ ジェネラル ホスピタル コーポレイション 導入遺伝子発現のための操作されたアデノ随伴（ａａｖ）ベクター
WO2020215149A1 (en) * 2019-04-24 2020-10-29 University Of Manitoba Flea beetle-specific rnai-based pesticides
CN110117606A (zh) * 2019-04-29 2019-08-13 贵州大学 一种马铃薯蚜虫效应蛋白Me10基因的重组载体和表达方法
TWI906251B (zh) 2020-02-04 2025-12-01 美商科迪華農業科技有限責任公司 具有殺有害生物效用之組成物及與其相關之方法
IL296024A (en) 2020-03-04 2022-10-01 Flagship Pioneering Innovations Vi Llc Methods and compositions for modulating a genome
JP2023525575A (ja) * 2020-05-13 2023-06-16 グリーンライト バイオサイエンシーズ インコーポレーテッド 鱗翅目害虫のｒｎａベースの防除
JP2023527764A (ja) * 2020-05-20 2023-06-30 クアンタム－エスアイ インコーポレイテッド タンパク質シーケンスのための方法及び組成物
US12168774B2 (en) 2020-07-14 2024-12-17 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
TWI784298B (zh) * 2020-08-06 2022-11-21 大江生醫股份有限公司 生物活性物質用於製備促進肌膚膠原蛋白質生成及提升肌膚膠原蛋白質密度的組合物的用途
EP4192848A1 (en) 2020-08-10 2023-06-14 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
US12129287B2 (en) 2020-09-14 2024-10-29 President And Fellows Of Harvard College Recombinant adeno associated virus encoding clarin-1 and uses thereof
WO2022140227A1 (en) 2020-12-21 2022-06-30 Monsanto Technolgy Llc Novel insect inhibitory proteins
UY39585A (es) 2020-12-23 2022-07-29 Monsanto Technology Llc Proteínas que exhiben actividad inhibidora de insectos frente a plagas con importancia agrícola de plantas de cultivo y semillas
KR20230127241A (ko) 2020-12-31 2023-08-31 몬산토 테크놀로지 엘엘씨 신규한 곤충 저해 단백질
EP4314257A4 (en) * 2021-04-01 2025-07-09 Prime Medicine Inc METHODS AND COMPOSITIONS FOR EDITING NUCLEOTIDE SEQUENCES
AU2022306570A1 (en) 2021-07-08 2024-01-18 Monsanto Technology Llc Novel insect inhibitory proteins
US11807685B2 (en) * 2021-08-05 2023-11-07 The Uab Research Foundation Anti-CD47 antibody and uses thereof
CN118302524A (zh) 2021-08-31 2024-07-05 纳诺索尔公司 高分子量修饰的dsRNA组合物
JP2024533311A (ja) 2021-09-08 2024-09-12 フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー ゲノムを調節するための方法及び組成物
TW202345696A (zh) 2022-05-18 2023-12-01 美商科迪華農業科技有限責任公司 具有殺有害生物效用之組成物及與其相關的方法
CN117025618B (zh) * 2023-07-24 2024-07-05 西南大学 一种对番茄红螨高效致死的靶标基因及其应用
WO2025038870A1 (en) * 2023-08-16 2025-02-20 Rnaissance Ag Llc Double stranded rna methods and compositions for insecticide
CN117187278B (zh) * 2023-10-17 2024-11-12 河北农业大学 一种用于防控蛴螬的dsHpVAA、dsRNA纳米复合物及其应用
WO2025103765A1 (en) * 2023-11-17 2025-05-22 Novozymes A/S Lytic polysaccharide monooxygenases and their use in detergent
US20250194603A1 (en) * 2023-12-14 2025-06-19 National Resources Institute Compositions and methods for management of whitefly
WO2025221793A1 (en) * 2024-04-16 2025-10-23 Monsanto Technology Llc Modified cas proteins for nuclear localization and editing activity in plants

Family Cites Families (175)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3937813A (en) * 1974-02-20 1976-02-10 Abbott Laboratories Insecticidal compositions comprising mixtures of bacillus thuringiensis and chlordimeform
US4272417A (en) 1979-05-22 1981-06-09 Cargill, Incorporated Stable protective seed coating
US4245432A (en) 1979-07-25 1981-01-20 Eastman Kodak Company Seed coatings
US4339456A (en) 1980-01-14 1982-07-13 Gustafson, Inc. Peanut seed treating
US4383391A (en) 1981-09-21 1983-05-17 Celanese Corporation Seed coating composition based on carbamate pesticide and non-alkaline amorphous carbon
US4634587A (en) 1982-07-09 1987-01-06 Key Pharmaceuticals, Inc. Sustained release quinidine dosage form
US4693977A (en) 1982-08-23 1987-09-15 Queen's University At Kingston Enzyme immobilization for producing cephalosporin antibiotics
US4536475A (en) 1982-10-05 1985-08-20 Phytogen Plant vector
US4876197A (en) 1983-02-22 1989-10-24 Chiron Corporation Eukaryotic regulatable transcription
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
US4465017A (en) 1983-03-09 1984-08-14 Simmons John J Seed coating machine
NZ207765A (en) 1983-04-15 1987-03-06 Lubrizol Genetics Inc Plant expression of transferred dna(t-dna)from plasmids associated with agrobacterium sp
JPS59205983A (ja) 1983-04-28 1984-11-21 ジエネツクス・コ−ポレイシヨン 異種遺伝子を原核微生物で発現させる方法
US4735015A (en) 1983-11-25 1988-04-05 Basf Corporation Seed protective coating
US4880734A (en) 1984-05-11 1989-11-14 Chiron Corporation Eukaryotic regulatable transcription
DE3587759T2 (de) 1984-05-11 1994-07-07 Chiron Corp., Emeryville, Calif. Erhöhte Hefetranskription unter Verwendung einer Hybridkonstruktion der Promotorregion.
US4886937A (en) 1985-05-20 1989-12-12 North Carolina State University Method for transforming pine
CA1293460C (en) 1985-10-07 1991-12-24 Brian Lee Sauer Site-specific recombination of dna in yeast
US5453566A (en) 1986-03-28 1995-09-26 Calgene, Inc. Antisense regulation of gene expression in plant/cells
US5107065A (en) 1986-03-28 1992-04-21 Calgene, Inc. Anti-sense regulation of gene expression in plant cells
DE3616010A1 (de) 1986-05-13 1987-11-19 Bayer Ag Verfahren zum beizen und/oder inkrustieren von saatgutkoernern
US5004863B2 (en) 1986-12-03 2000-10-17 Agracetus Genetic engineering of cotton plants and lines
US5015580A (en) 1987-07-29 1991-05-14 Agracetus Particle-mediated transformation of soybean plants and lines
DE3703584A1 (de) 1987-02-06 1988-08-18 Consortium Elektrochem Ind Aldehyde und alkohole mit 3-methyl- oder 3,5-dimethylphenylgruppen, deren herstellung und verwendung als duftstoffe
DE3888561T2 (de) 1987-03-23 1994-09-01 Zymogenetics Inc Hohe Proteinsyntheserate in Hefe.
TR27832A (tr) 1987-04-29 1995-08-31 Monsanto Co Zararli ucucu hasarata mukavim bitkiler.
JPH01501660A (ja) 1987-06-18 1989-06-08 ユニシス・コーポレーシヨン コンピユータ間通信制御装置及びその方法
FR2618041B1 (fr) 1987-07-16 1991-06-21 Ceres Ets Dispositif pour le traitement des semences
US4948734A (en) * 1987-08-12 1990-08-14 Mycogen Corporation Novel isolates of bacillus thuringiensis having activity against nematodes
EP0315447A3 (en) 1987-11-06 1990-07-18 Teijin Limited Method of immunological measurement of human protein s and reagent and kit therefor
US5614395A (en) 1988-03-08 1997-03-25 Ciba-Geigy Corporation Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
US5789214A (en) 1988-03-08 1998-08-04 Novartis Finance Corporation Method of inducing gene transcription in a plant
US5416011A (en) 1988-07-22 1995-05-16 Monsanto Company Method for soybean transformation and regeneration
JPH0646887B2 (ja) 1988-11-08 1994-06-22 矢崎総業株式会社 種子のゲル被覆装置
US5300127A (en) 1989-01-06 1994-04-05 Agricultural Genetics Company Limited Seed coatings
DK0413019T3 (da) * 1989-02-24 2001-11-12 Monsanto Technology Llc Syntetiske plantegener og fremgangsmåde til fremstilling af disse
US5231020A (en) * 1989-03-30 1993-07-27 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
EP0400246A1 (en) * 1989-05-31 1990-12-05 Plant Genetic Systems, N.V. Prevention of Bt resistance development
US5501967A (en) 1989-07-26 1996-03-26 Mogen International, N.V./Rijksuniversiteit Te Leiden Process for the site-directed integration of DNA into the genome of plants
US5550318A (en) 1990-04-17 1996-08-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US7705215B1 (en) 1990-04-17 2010-04-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US5484956A (en) 1990-01-22 1996-01-16 Dekalb Genetics Corporation Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin
JP3209744B2 (ja) 1990-01-22 2001-09-17 デカルブ・ジェネティクス・コーポレーション 結実能力のある遺伝子変換コーン
US5837848A (en) 1990-03-16 1998-11-17 Zeneca Limited Root-specific promoter
US5639949A (en) 1990-08-20 1997-06-17 Ciba-Geigy Corporation Genes for the synthesis of antipathogenic substances
US5633435A (en) 1990-08-31 1997-05-27 Monsanto Company Glyphosate-tolerant 5-enolpyruvylshikimate-3-phosphate synthases
ATE191931T1 (de) 1990-11-23 2000-05-15 Plant Genetic Systems Nv Verfahren zur transformation monokotyler pflanzen
ATE207126T1 (de) 1991-05-15 2001-11-15 Monsanto Technology Llc Verfahren zur schöpfung einer transformierten reispflanze
DK0595894T3 (da) 1991-07-19 1996-05-13 Uniroyal Chem Co Inc Frøfilmsammensætninger
CA2119155C (en) 1991-10-18 1999-06-15 Dennis Paul Phillion Fungicides for the control of take-all disease of plants
US5593874A (en) 1992-03-19 1997-01-14 Monsanto Company Enhanced expression in plants
CA2094658A1 (en) 1992-04-23 1993-10-24 Martin Sumner-Smith Intracellular delivery of biochemical agents
JPH08501928A (ja) 1992-07-02 1996-03-05 ハイブライドン インコーポレイテッド 治療剤としての自己安定化オリゴヌクレオチド
DE69334225D1 (de) 1992-07-07 2008-07-31 Japan Tobacco Inc Verfahren zur transformation einer monokotyledon pflanze
FI93687C (fi) 1992-07-29 1995-05-26 Novasso Oy Menetelmä siementen päällystämiseksi
US5661103A (en) 1992-11-05 1997-08-26 Donlar Corporation Seed treatment composition and method
US5527695A (en) 1993-01-29 1996-06-18 Purdue Research Foundation Controlled modification of eukaryotic genomes
US6118047A (en) 1993-08-25 2000-09-12 Dekalb Genetic Corporation Anthranilate synthase gene and method of use thereof for conferring tryptophan overproduction
US5629469A (en) * 1994-03-10 1997-05-13 Sandoz Ltd. Thiol protease inhibitor
US5882713A (en) 1994-04-26 1999-03-16 The United States Of America As Represented By The Secretary Of Agriculture Non-separable compositions of starch and water-immiscible organic materials
US5662897A (en) * 1994-07-27 1997-09-02 U. Of Ga Research Foundation Insect viruses, sequences, insecticidal compositions and methods of use
US5631152A (en) 1994-10-26 1997-05-20 Monsanto Company Rapid and efficient regeneration of transgenic plants
US5716837A (en) * 1995-02-10 1998-02-10 Monsanto Company Expression of sucrose phosphorylase in plants
US5580544A (en) 1995-03-29 1996-12-03 Uniroyal Chemical Company, Inc. Paste formulation useful for seed treatment and foliar treatment of plants
JP3125847B2 (ja) 1995-06-15 2001-01-22 矢崎総業株式会社 ゲル被覆種子のゲル層易崩壊処理方法
US5622003A (en) 1995-07-11 1997-04-22 Isp Investments Inc. Seed coating containing Mn (NO3)2 ·6H2 O
US5693512A (en) 1996-03-01 1997-12-02 The Ohio State Research Foundation Method for transforming plant tissue by sonication
US5849320A (en) 1996-06-13 1998-12-15 Novartis Corporation Insecticidal seed coating
US5876739A (en) 1996-06-13 1999-03-02 Novartis Ag Insecticidal seed coating
US5939356A (en) 1996-06-21 1999-08-17 Southwest Research Institute Controlled release coated agricultural products
DE19631919C2 (de) 1996-08-07 1998-07-16 Deutsches Krebsforsch Anti-Sinn-RNA mit Sekundärstruktur
US6603063B1 (en) * 1999-05-07 2003-08-05 Mycogen Corp. Plants and cells transformed with a nucleic acid from Bacillus thuringiensis strain KB59A4-6 encoding a novel SUP toxin
US5942664A (en) * 1996-11-27 1999-08-24 Ecogen, Inc. Bacillus thuringiensis Cry1C compositions toxic to lepidopteran insects and methods for making Cry1C mutants
JP3185133B2 (ja) 1997-02-13 2001-07-09 タキイ種苗株式会社 造粒コーティング種子およびその製造方法
AU727218B2 (en) 1997-04-03 2000-12-07 Syngenta Participations Ag Plant pest control
GB9710475D0 (en) * 1997-05-21 1997-07-16 Zeneca Ltd Gene silencing
ATE225858T1 (de) 1997-07-28 2002-10-15 Medical Biosystems Ltd Sequenzanalyse von nukleinsäuren
US5891246A (en) 1997-08-15 1999-04-06 Gustafson, Inc. Seed coating apparatus
US5879827A (en) 1997-10-10 1999-03-09 Minnesota Mining And Manufacturing Company Catalyst for membrane electrode assembly and method of making
US20090077685A1 (en) 1998-06-16 2009-03-19 Buehler Robert E Nucleic acid molecules and other molecules associated with plants
AUPP058797A0 (en) 1997-11-28 1997-12-18 Commonwealth Scientific And Industrial Research Organisation Novel gene
US6037160A (en) 1997-12-12 2000-03-14 Heska Corporation Flea epoxide hydrolase nucleic acid molecules, proteins and uses thereof
US6060594A (en) 1997-12-18 2000-05-09 Ecogen, Inc. Nucleic acid segments encoding modified bacillus thuringiensis coleopteran-toxic crystal proteins
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
IL136516A0 (en) 1998-01-09 2001-06-14 Novartis Ag Coating of polymers
AUPP135698A0 (en) 1998-01-15 1998-02-05 Commonwealth Scientific And Industrial Research Organisation Insectical modalities
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
KR20010042069A (ko) * 1998-03-20 2001-05-25 베니텍 오스트레일리아 리미티드 유전자 발현 조절방법
CN1302335A (zh) 1998-03-23 2001-07-04 拉尔夫·施纳贝尔 轰击转化秀丽新杆线虫的方法
EP2267138B1 (en) 1998-04-08 2016-06-08 Commonwealth Scientific and Industrial Research Organization Methods and means for obtaining modified phenotypes
AR020078A1 (es) 1998-05-26 2002-04-10 Syngenta Participations Ag Metodo para alterar la expresion de un gen objetivo en una celula de planta
GB9827152D0 (en) 1998-07-03 1999-02-03 Devgen Nv Characterisation of gene function using double stranded rna inhibition
ATE506441T1 (de) 1998-08-19 2011-05-15 Monsanto Technology Llc Pflanzliche expressionsvektoren
US6506599B1 (en) 1999-10-15 2003-01-14 Tai-Wook Yoon Method for culturing langerhans islets and islet autotransplantation islet regeneration
US6489542B1 (en) 1998-11-04 2002-12-03 Monsanto Technology Llc Methods for transforming plants to express Cry2Ab δ-endotoxins targeted to the plastids
GB9826890D0 (en) 1998-12-07 1999-01-27 Devgen Nv Method for screening compounds
JP2002534129A (ja) 1999-01-14 2002-10-15 モンサント テクノロジー エルエルシー ダイズ形質転換方法
US6417208B1 (en) 1999-02-05 2002-07-09 Albert Einstein College Of Medicine Of Yeshiva University Method of identification of inhibitors of PDE1C
GB9906018D0 (en) 1999-03-16 1999-05-12 Devgen Nv Expression of DNA or proteins in C.elegans
US6511824B1 (en) 1999-03-17 2003-01-28 Exelixis, Inc. Nucleic acids and polypeptides of invertebrate TWIK channels and methods of use
US6703491B1 (en) * 1999-03-17 2004-03-09 Exelixis, Inc. Drosophila sequences
WO2000061621A2 (en) * 1999-04-09 2000-10-19 Heska Corporation Flea head, nerve cord, hindgut and malpighian tubule nucleic acid molecules, proteins and uses thereof
GB9908677D0 (en) 1999-04-15 1999-06-09 Devgen Nv Compound assay
GB9908676D0 (en) 1999-04-15 1999-06-09 Devgen Nv Method for screening compounds
CA2371442A1 (en) 1999-05-04 2000-11-09 Monsanto Technology Llc Coleopteran-toxic polypeptide compositions and insect-resistant transgenic plants
US6551800B1 (en) * 1999-10-26 2003-04-22 The Board Of Regents, The University Texas System Recombinant materials for production of a protein toxic to fire ants
GB9925459D0 (en) 1999-10-27 1999-12-29 Plant Bioscience Ltd Gene silencing
US6326193B1 (en) 1999-11-05 2001-12-04 Cambria Biosciences, Llc Insect control agent
AU2047001A (en) * 1999-11-24 2001-06-04 Dna Plant Technology Corporation Methods of inhibiting plant parasitic nematodes and insect pests by expression of nematode and insect specific double-stranded rna in plants
GB9930691D0 (en) 1999-12-24 2000-02-16 Devgen Nv Improvements relating to double-stranded RNA inhibition
RU2157644C1 (ru) 2000-01-21 2000-10-20 Авакян Юрий Арамович Пищевой и кормовой продукт с повышенным содержанием балластных веществ и способ его получения
ATE454456T1 (de) * 2000-02-11 2010-01-15 Metabolix Inc Intein enthaltende multigen-expressionskonstrukte
AU2001247587A1 (en) 2000-03-20 2001-10-03 Arch Development Corporation Transgenic plants containing heat shock protein
AU2001250572A1 (en) 2000-04-07 2001-10-23 Epigenomics Ag Detection of single nucleotide polymorphisms (snp's) and cytosine-methylations
US20110131679A2 (en) * 2000-04-19 2011-06-02 Thomas La Rosa Rice Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement
WO2001087940A2 (en) 2000-05-15 2001-11-22 Monsanto Technology Llc Polypeptide composionns toxic to anthonomus insects, and use thereof
GB0012233D0 (en) 2000-05-19 2000-07-12 Devgen Nv Vector constructs
WO2001091559A2 (en) 2000-05-30 2001-12-06 Pieter Lodewikus Steyn Bacillus thuringiensis as insect repellent
GB0014009D0 (en) 2000-06-08 2000-08-02 Devgen Nv Compound screens relating to insulin deficiency or insulin resistance
GB0017224D0 (en) 2000-07-14 2000-08-30 Crocker John G Hand and wrist support
AU2001291259A1 (en) 2000-08-11 2002-02-25 The Regents Of The University Of California Methods for blocking resistance to BT toxins in insects and nematodes
US7109393B2 (en) 2000-08-15 2006-09-19 Mendel Biotechnology, Inc. Methods of gene silencing using inverted repeat sequences
US20020048814A1 (en) 2000-08-15 2002-04-25 Dna Plant Technology Corporation Methods of gene silencing using poly-dT sequences
US6812339B1 (en) 2000-09-08 2004-11-02 Applera Corporation Polymorphisms in known genes associated with human disease, methods of detection and uses thereof
US6660690B2 (en) * 2000-10-06 2003-12-09 Monsanto Technology, L.L.C. Seed treatment with combinations of insecticides
US6586365B2 (en) * 2000-10-06 2003-07-01 Monsanto Technology, Llc Method for reducing pest damage to corn by treating transgenic corn seeds with clothianidin pesticide
US6551962B1 (en) 2000-10-06 2003-04-22 Monsanto Technology Llc Method for deploying a transgenic refuge
WO2002033405A1 (en) 2000-10-18 2002-04-25 Devgen Nv Methods for identifying pesticidal compounds
EP1210875A1 (en) 2000-12-04 2002-06-05 Aventis CropScience GmbH Modulating gene expression in insects by using double-stranded RNA (dsRNA)
WO2002077183A2 (en) 2001-03-21 2002-10-03 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
AUPR621501A0 (en) 2001-07-06 2001-08-02 Commonwealth Scientific And Industrial Research Organisation Delivery of ds rna
US7612194B2 (en) * 2001-07-24 2009-11-03 Monsanto Technology Llc Nucleic acid sequences from Diabrotica virgifera virgifera LeConte and uses thereof
US7230167B2 (en) 2001-08-31 2007-06-12 Syngenta Participations Ag Modified Cry3A toxins and nucleic acid sequences coding therefor
BRPI0212339B1 (pt) * 2001-09-05 2018-09-11 Monsanto Technology Llc método de transformação de uma planta, molécula de ácido nucleico recombinante, vetor e célula
EP1578911A2 (en) * 2001-10-10 2005-09-28 Heska Corporation Flea head, nerve cord, hindgut and malpighian tubule nucleic acid molecules, proteins and uses thereof
US20030150017A1 (en) 2001-11-07 2003-08-07 Mesa Jose Ramon Botella Method for facilitating pathogen resistance
US6766613B2 (en) 2001-11-16 2004-07-27 University Of Florida Research Foundation, Inc. Materials and methods for controlling pests
US7314974B2 (en) 2002-02-21 2008-01-01 Monsanto Technology, Llc Expression of microbial proteins in plants for production of plants with improved properties
BR0308424A (pt) * 2002-03-14 2005-02-22 Commw Scient Ind Res Org Métodos e meios para infra-regular eficientemente a expressão de qualquer gene de interesse em células e organismos eucarióticos
US20040053876A1 (en) * 2002-03-26 2004-03-18 The Regents Of The University Of Michigan siRNAs and uses therof
WO2004001000A2 (en) 2002-06-21 2003-12-31 Monsanto Technology Llc Intron double stranded rna constructs and uses thereof
BR0312580A (pt) 2002-07-10 2006-10-10 Univ Kansas State composições e métodos para controlar nematódeos parasitas
RU2352638C2 (ru) * 2002-07-29 2009-04-20 Монсанто Текнолоджи Ллс Растения-трансформанты кукурузы pv-zmir13 (mon863) и композиции и способы их обнаружения
US7205454B2 (en) 2002-07-31 2007-04-17 Bayer Bioscience N.V. Corn root preferential promoters and uses thereof
US20040053289A1 (en) 2002-09-09 2004-03-18 The Regents Of The University Of California Short interfering nucleic acid hybrids and methods thereof
US20040048261A1 (en) 2002-09-11 2004-03-11 Klaus Raming Invertebrate choline transporter nucleic acids, polypeptides and uses thereof
WO2004035765A2 (en) * 2002-10-18 2004-04-29 Nucleonics, Inc. Double-stranded rna structures and constructs, and methods for generating and using the same
US7250496B2 (en) * 2002-11-14 2007-07-31 Rosetta Genomics Ltd. Bioinformatically detectable group of novel regulatory genes and uses thereof
CN1412311A (zh) * 2002-11-26 2003-04-23 西南农业大学 利用侵染相关基因的协同作用提高微生物杀虫效果的方法
CA2516310C (en) 2003-02-19 2014-12-09 Commonwealth Scientific And Industrial Research Organisation Efficient gene silencing in plants using short dsrna sequences
CA2528162A1 (en) 2003-06-04 2004-12-16 The Government Of The United States As Represented By The Secretary Of T He Department Of Health And Human Services, Centers For Disease Control Pni microarray and uses
US8796026B2 (en) 2003-07-07 2014-08-05 Monsanto Technology Llc Insecticidal proteins secreted from Bacillus thuringiensis and uses therefor
IL157538A0 (en) 2003-08-21 2004-03-28 Bar Ilan Res & Dev Company Ltd Plant resistant to cytoplasm-feeding parasites
US7266831B2 (en) * 2003-10-14 2007-09-04 Byeong-Seon Bak Insertion type compact disc case
ATE526407T1 (de) * 2003-11-17 2011-10-15 Commw Scient Ind Res Org Insektenresistenz durch inhibierung von genexpression
ES2353603T3 (es) 2003-12-16 2011-03-03 Monsanto Technology Llc Proteína insecticida secretada y composiciones de genes de bacillus thuringiensis y sus usos.
WO2005071091A1 (fr) * 2003-12-23 2005-08-04 Bayer Cropscience Sa Methode pour modifier l'expression genique d'un champignon phytopathogene
US7622301B2 (en) 2004-02-24 2009-11-24 Basf Plant Science Gmbh Compositions and methods using RNA interference for control of nematodes
CN1997737B (zh) 2004-04-09 2018-11-30 孟山都技术有限公司 用于在植物中控制昆虫侵袭的组合物和方法
PT1818405E (pt) 2004-04-09 2015-10-20 Monsanto Technology Llc Composições e métodos para o controlo de infestações de plantas por insectos
WO2006070227A2 (en) 2004-10-04 2006-07-06 Devgen Nv Method for down-regulating gene expression in fungi
WO2006046148A2 (en) 2004-10-25 2006-05-04 Devgen Nv Rna constructs
WO2006045590A2 (en) 2004-10-25 2006-05-04 Devgen N.V. Multidomain rna molecules comprising at least one aptamer for delivering double stranded rna to pest organisms
US8772254B2 (en) 2004-10-25 2014-07-08 Devgen N.V. Method and constructs for delivering double stranded RNA to pest organisms
US20060200878A1 (en) * 2004-12-21 2006-09-07 Linda Lutfiyya Recombinant DNA constructs and methods for controlling gene expression
US8404927B2 (en) * 2004-12-21 2013-03-26 Monsanto Technology Llc Double-stranded RNA stabilized in planta
AU2006203892B2 (en) * 2005-01-07 2011-03-24 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Method to trigger RNA interference
US8088976B2 (en) 2005-02-24 2012-01-03 Monsanto Technology Llc Methods for genetic control of plant pest infestation and compositions thereof
EP1907546A2 (en) 2005-05-31 2008-04-09 Devgen N.V. Rnai for control of insects and arachnids
US8853489B2 (en) 2005-09-16 2014-10-07 Devgen Nv Transgenic plant-based methods for plant pests using RNAi
PT2270181E (pt) 2005-09-16 2016-01-26 Devgen Nv Arncd como agente de controlo de insetos
SG166097A1 (en) * 2005-09-16 2010-11-29 Monsanto Technology Llc Methods for genetic control of insect infestations in plants and compositions thereof
CN101384721A (zh) 2006-02-13 2009-03-11 孟山都技术有限公司 选择和稳定dsRNA构建体
US7999148B2 (en) 2006-02-16 2011-08-16 Texas A&M University System Cotton plant with seed-specific reduction in gossypol
ES2651911T3 (es) 2007-08-14 2018-01-30 Commonwealth Scientific And Industrial Research Organisation Métodos mejorados de silenciamiento génico

Also Published As

Publication number Publication date
US7812219B2 (en) 2010-10-12
US20080214443A1 (en) 2008-09-04
HK1098014A1 (en) 2007-07-13
EP2308971A1 (en) 2011-04-13
US10787680B2 (en) 2020-09-29
AU2005244258A2 (en) 2005-11-24
ZA200607995B (en) 2008-01-08
AU2005244258A1 (en) 2005-11-24
EP1818405B2 (en) 2025-03-19
EP1818405A3 (en) 2008-03-12
EP1732379A4 (en) 2008-02-27
CN105002208A (zh) 2015-10-28
HK1106790A1 (en) 2008-03-20
US20130232646A1 (en) 2013-09-05
BRPI0509743A (pt) 2007-09-25
US20220267793A1 (en) 2022-08-25
ES2547381T3 (es) 2015-10-05
EP1732379A2 (en) 2006-12-20
US11492638B2 (en) 2022-11-08
EP1818405A2 (en) 2007-08-15
CN102524294B (zh) 2018-04-06
US20060021087A1 (en) 2006-01-26
EP1732379B1 (en) 2013-11-06
CA2562022C (en) 2016-01-26
EP1818405B1 (en) 2015-06-03
PL1818405T3 (pl) 2015-11-30
ECSP066908A (enExample) 2007-01-26
AU2010226899B2 (en) 2012-03-29
US20210087580A1 (en) 2021-03-25
PL1732379T3 (pl) 2014-04-30
US8946510B2 (en) 2015-02-03
WO2005110068A2 (en) 2005-11-24
WO2005110068A8 (en) 2006-02-23
PT1732379E (pt) 2014-01-03
US20120164205A1 (en) 2012-06-28
US10167484B2 (en) 2019-01-01
US20180073037A1 (en) 2018-03-15
EP2308971B1 (en) 2016-08-17
MXPA06011694A (es) 2006-12-14
CN102524294A (zh) 2012-07-04
AR048685A1 (es) 2006-05-17
US20160237453A1 (en) 2016-08-18
US20200109413A1 (en) 2020-04-09
CA2693280C (en) 2017-09-12
CA2762011A1 (en) 2005-11-24
AU2005244258B2 (en) 2010-07-01
AU2010226899A1 (en) 2010-10-21
US12077770B2 (en) 2024-09-03
US11685930B2 (en) 2023-06-27
US9238822B2 (en) 2016-01-19
CA2693280A1 (en) 2005-11-24
US20090307803A1 (en) 2009-12-10
WO2005110068A3 (en) 2007-01-25
EP2402441A1 (en) 2012-01-04
US9340797B2 (en) 2016-05-17
PT1818405E (pt) 2015-10-20
ES2439696T3 (es) 2014-01-24
CA2562022A1 (en) 2005-11-24

Similar Documents

Publication Publication Date Title
US12077770B2 (en) Compositions and methods for control of insect infestations in plants
CN101422167A (zh) 用于在植物中控制昆虫侵袭的组合物和方法
AU2011253615B2 (en) Compositions and methods for control of insect infestations in plants
AU2007214372B2 (en) Compositions and methods for control of insect infestations in plants
HK1106790B (en) Compositions and methods for control of insect infestations in plants
HK1098014B (en) Compositions and methods for control of insect infestations in plants

Legal Events

Date Code Title Description
EEER Examination request