AR109205A1 - Control de plagas de coleópteros utilizando moléculas de arn - Google Patents

Control de plagas de coleópteros utilizando moléculas de arn

Info

Publication number
AR109205A1
AR109205A1 ARP170102161A ARP170102161A AR109205A1 AR 109205 A1 AR109205 A1 AR 109205A1 AR P170102161 A ARP170102161 A AR P170102161A AR P170102161 A ARP170102161 A AR P170102161A AR 109205 A1 AR109205 A1 AR 109205A1
Authority
AR
Argentina
Prior art keywords
seq
insecticidal protein
insecticidal
diabrotica
nucleic acid
Prior art date
Application number
ARP170102161A
Other languages
English (en)
Inventor
Isabelle Maillet
Lies Degrave
Pascale Feldmann
Yann Naudet
Kevin V Donohue
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of AR109205A1 publication Critical patent/AR109205A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C07K14/42—Lectins, e.g. concanavalin, phytohaemagglutinin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325—Bacillus thuringiensis crystal protein (delta-endotoxin)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2442—Chitinase (3.2.1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed
    • C12N2310/531—Stem-loop; Hairpin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01014—Chitinase (3.2.1.14)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Abstract

Reivindicación 1: Una molécula de ácido ribonucleico interferente (ARN) donde el ARN comprende al menos un ARNbc, donde el ARNbc es una región de ARN bicatenario que comprende hebras complementarias hibridadas, donde una de las hebras comprende una secuencia de al menos 19 nucleótidos contiguos que es al menos parcialmente complementaria a una secuencia de nucleótidos diana dentro de un gen diana de Diabrotica spp, y (i) es idéntica en al menos un 85% a un fragmento de al menos 19 nucleótidos contiguos de las SEQ ID Nº 121 - 210, SEQ ID Nº 274 - 276, SEQ ID Nº 280 - 282, SEQ ID Nº 298 - 312, SEQ ID Nº 345 - 371, SEQ ID Nº 373, 374, 378, 380, 389 - 396, 399, 400, o una de sus complementarias; (ii) comprende al menos un fragmento de 19 nucleótidos contiguos de las SEQ ID Nº 121 - 210, SEQ ID Nº 274 - 276, SEQ ID Nº 280 - 282, SEQ ID Nº 298 - 312, SEQ ID Nº 345 - 371, SEQ ID Nº 373, 374, 378, 380, 389 - 396, 399, 400, o una de sus complementarias; (iii) comprende al menos un fragmento de 19 nucleótidos contiguos de una secuencia de nucleótidos que codifica una secuencia de aminoácidos codificada por las SEQ ID Nº 121 - 210, SEQ ID Nº 274 - 276, SEQ ID Nº 280 - 282, SEQ ID Nº 298 - 312, SEQ ID Nº 345 - 371, SEQ ID Nº 373, 374, 378, 380, 389 - 396, 399, 400, o sus complementarias, o (iv) se puede hibridar en condiciones rigurosas con un polinucleótido seleccionado a partir del grupo constituido por las SEQ ID Nº 121 - 210, SEQ ID Nº 274 - 276, SEQ ID Nº 280 - 282, SEQ ID Nº 298 - 312, SEQ ID Nº 345 - 371, SEQ ID Nº 373, 374, 378, 380, 389 - 396, 399, 400, y sus complementarias, donde la molécula de ARN interferente tiene actividad insecticida sobre una plaga de coleópteros que atacan plantas. Reivindicación 9: Un constructo de ácido nucleico que comprende la molécula de ARN interferente de cualquiera de las reivindicaciones 1 a 8. Reivindicación 14: Una composición que comprende dos o más de las moléculas de ARN interferente de cualquiera de las reivindicaciones 1 a 8. Reivindicación 24: Una composición insecticida de la reivindicación 22, donde el segundo agente insecticida es una proteína insecticida de Bacillus cereus, una proteína insecticida de Xenorhabdus spp., una proteína insecticida de Photorhabdus spp., una proteína insecticida de Brevibacillus laterosporous, una proteína insecticida de Lysinibacillus sphearicus, una proteína insecticida de Chromobacterium ssp., una proteína insecticida de Yersinia entomophaga, una proteína insecticida de Paenibacillus popiliae o una proteína insecticida de Clostridium spp o se deriva de estas. Reivindicación 25: Una planta transgénica, o parte de esta, que comprende la molécula de ARN interferente, la molécula de ácido nucleico, el constructo de ácido nucleico y/o la composición de cualquiera de las respectivas reivindicaciones anteriores, donde la planta transgénica presenta una mayor resistencia a un insecto de Diabrotica en comparación con una planta de control. Reivindicación 43: Un método para controlar un insecto de Diabrotica que comprende poner en contacto el insecto de Diabrotica con una molécula de ácido nucleico que es una molécula de ARN interferente de las reivindicaciones 1 - 8, o que es capaz de producirla, para inhibir la expresión de un gen diana en el insecto de Diabrotica y poner en contacto el insecto de Diabrotica con al menos un segundo agente insecticida para controlar el insecto de Diabrotica. Reivindicación 62: Un método para producir una planta transgénica con una mayor tolerancia al daño debido a la alimentación de insectos de Diabrotica que comprende introducir en una planta la molécula de ARN interferente, la molécula de ácido nucleico o el constructo de ácido nucleico de cualquiera de las respectivas reivindicaciones anteriores, con el fin de producir de este modo una planta transgénica con una mayor tolerancia al daño debido a la alimentación de insectos de Diabrotica en comparación con una planta de control.
ARP170102161A 2016-08-05 2017-07-31 Control de plagas de coleópteros utilizando moléculas de arn AR109205A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662371259P 2016-08-05 2016-08-05

Publications (1)

Publication Number Publication Date
AR109205A1 true AR109205A1 (es) 2018-11-07

Family

ID=61073121

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP170102161A AR109205A1 (es) 2016-08-05 2017-07-31 Control de plagas de coleópteros utilizando moléculas de arn

Country Status (8)

Country Link
US (1) US11945843B2 (es)
EP (2) EP3494222A4 (es)
CN (1) CN109790544A (es)
AR (1) AR109205A1 (es)
BR (1) BR112019002186A2 (es)
CA (1) CA3031143A1 (es)
MX (2) MX2019001292A (es)
WO (1) WO2018026770A2 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR109205A1 (es) 2016-08-05 2018-11-07 Syngenta Participations Ag Control de plagas de coleópteros utilizando moléculas de arn
WO2019162163A1 (en) 2018-02-26 2019-08-29 Devgen Nv Control of insect pests using rna molecules
EP3784784A1 (en) 2018-04-27 2021-03-03 Devgen NV Control of insect pests using rna molecules
CN110551718B (zh) 2018-05-31 2021-07-30 北京大北农生物技术有限公司 用于控制昆虫侵袭的核苷酸序列及其方法
WO2020081487A1 (en) * 2018-10-15 2020-04-23 Greenlight Biosciences, Inc. Control of coleopteran insect infestation
WO2020187798A1 (en) 2019-03-21 2020-09-24 Devgen Nv Control of insect pests using rna molecules
CN112391390A (zh) * 2020-11-19 2021-02-23 山西大学 飞蝗网格蛋白重链基因及其靶向dsRNA的合成与应用
EP4263799A1 (en) 2020-12-17 2023-10-25 Basf Se Spore compositions, production and uses thereof
CA3226637A1 (en) * 2021-08-12 2023-02-16 Clarence Michael REYNOLDS Compositions and methods for controlling coleopteran insects
CN116836809B (zh) * 2023-09-01 2023-11-21 暨南大学 具有高虾青素含量类外泌体的基因工程微拟球藻及其应用

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE100141T1 (de) 1984-03-06 1994-01-15 Mgi Pharma Inc Herbizide resistenz in pflanzen.
TR27832A (tr) 1987-04-29 1995-08-31 Monsanto Co Zararli ucucu hasarata mukavim bitkiler.
US5451513A (en) 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
US5994629A (en) 1991-08-28 1999-11-30 Novartis Ag Positive selection
GB9304200D0 (en) 1993-03-02 1993-04-21 Sandoz Ltd Improvements in or relating to organic compounds
US5304730A (en) 1991-09-03 1994-04-19 Monsanto Company Virus resistant plants and method therefore
DE4317845A1 (de) 1993-05-28 1994-12-01 Bayer Ag Desoxyribonukleinsäuren
US5576198A (en) 1993-12-14 1996-11-19 Calgene, Inc. Controlled expression of transgenic constructs in plant plastids
US5545817A (en) 1994-03-11 1996-08-13 Calgene, Inc. Enhanced expression in a plant plastid
US5545818A (en) 1994-03-11 1996-08-13 Calgene Inc. Expression of Bacillus thuringiensis cry proteins in plant plastids
DE69535563T2 (de) 1994-12-30 2008-03-20 Seminis Vegetable Seeds, Inc., Saticoy Transgene pflanzen, die dna-konstrukte expremieren, die mehrere virusresistenz-verleihende gene enthalten
US5849320A (en) 1996-06-13 1998-12-15 Novartis Corporation Insecticidal seed coating
US5876739A (en) 1996-06-13 1999-03-02 Novartis Ag Insecticidal seed coating
US6121436A (en) 1996-12-13 2000-09-19 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
ES2308327T3 (es) 1997-11-18 2008-12-01 Pioneer Hi-Bred International, Inc. Composiciones y metodos para modificacion genetica de plantas.
ATE317440T1 (de) 1997-11-18 2006-02-15 Pioneer Hi Bred Int Neuartige methode zur integration von fremd-dna ins eukaryotische genom
NZ504510A (en) 1997-11-18 2002-10-25 Pioneer Hi Bred Int Methods and compositions for increasing efficiency of excision of a viral replicon from T-DNA that is transferred to a plant by agroinfection
AU1526199A (en) 1997-11-18 1999-06-07 Pioneer Hi-Bred International, Inc. Targeted manipulation of herbicide-resistance genes in plants
RU2306339C2 (ru) 1999-06-25 2007-09-20 Басф Акциенгезелльшафт ГЕНЫ Corynebacterium glutamicum, КОДИРУЮЩИЕ БЕЛКИ МЕТАБОЛИЧЕСКИХ ПУТЕЙ
RU2310686C2 (ru) 1999-06-25 2007-11-20 Басф Акциенгезелльшафт Гены corynebacterium glutamicum, кодирующие белки, участвующие в метаболизме углерода и продуцировании энергии
US6326193B1 (en) 1999-11-05 2001-12-04 Cambria Biosciences, Llc Insect control agent
US7612194B2 (en) 2001-07-24 2009-11-03 Monsanto Technology Llc Nucleic acid sequences from Diabrotica virgifera virgifera LeConte and uses thereof
US20050144669A1 (en) 2003-07-01 2005-06-30 Whitehead Institute For Biomedical Research MicroRNAs in plants
BRPI0412390A (pt) 2003-07-07 2006-09-19 Monsanto Technology Llc proteìnas inseticidas secretadas de espécies bacillus e uso dessas proteìnas
EP2361984A1 (en) 2003-10-09 2011-08-31 E. I. du Pont de Nemours and Company Gene silencing by using modified micro-RNA molecules
WO2005103301A2 (en) 2004-03-25 2005-11-03 Syngenta Participations Ag Corn event mir604
US20160230185A1 (en) * 2013-03-14 2016-08-11 Monsanto Technology Llc Compositions and methods for controlling diabrotica
CA2762011C (en) 2004-04-09 2019-05-07 Monsanto Technology Llc Compositions and methods for control of insect infestations in plants
US20100170000A9 (en) 2004-10-25 2010-07-01 Devgen Nv Rna constructs
TWI390037B (zh) 2005-09-16 2013-03-21 Monsanto Technology Llc 用於植物之昆蟲感染的基因控制方法及其組合物
EP2348115A3 (en) 2006-01-12 2012-01-18 deVGen N.V. Transgenic plant-based methods for plant pests using RNAi
BRPI0707626A2 (pt) 2006-02-10 2011-05-10 Monsanto Technology Llc identificaÇço e uso de genes alvos para o controle de nematàides parasitas de plantas
MX348698B (es) 2008-12-16 2017-06-26 Syngenta Participations Ag Evento 5307 del maiz.
EP3401404A1 (en) 2009-08-28 2018-11-14 E. I. du Pont de Nemours and Company Compositions and methods to control insect pests
US9102946B2 (en) * 2010-12-30 2015-08-11 Dow Agrosciences Llc Nucleic acid molecules that confer resistance to coleopteran pests
AP2013007005A0 (en) 2010-12-30 2013-07-31 Dow Agrosciences Llc Nucleic acid molecules that target the RHO1 small GTP-binding protein and confer resistance to coleopteran pests
RU2644669C2 (ru) * 2010-12-30 2018-02-13 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Молекулы нуклеиновой кислоты, которые воздействуют на субъединицу с вакуолярной атфазы и придают устойчивость к жесткокрылым насекомым-вредителям
CN110452908A (zh) * 2011-04-20 2019-11-15 德福根有限公司 在昆虫害虫中下调基因表达
WO2013192256A1 (en) 2012-06-22 2013-12-27 Syngenta Participations Ag Biological control of coleopteran pests
US10683505B2 (en) * 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
US9920316B2 (en) * 2013-03-14 2018-03-20 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
US20150257389A1 (en) 2014-03-14 2015-09-17 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
EP3140406B1 (en) 2014-05-07 2022-06-29 Dow AgroSciences LLC Dre4 nucleic acid molecules that confer resistance to coleopteran pests
KR20170067756A (ko) 2014-10-13 2017-06-16 다우 아그로사이언시즈 엘엘씨 딱정벌레류 및 노린재류 해충에 대한 저항성을 부여하는 copi 코토머 감마 서브유닛 핵산 분자
TW201629220A (zh) 2014-12-16 2016-08-16 陶氏農業科學公司 以駝背基因之親代ＲＮＡ干擾（ＲＮＡｉ）抑制作用來控制鞘翅目害蟲之技術
US10604757B2 (en) 2014-12-23 2020-03-31 Syngenta Participations Ag Biological control of coleopteran pests
BR112017018330A2 (pt) 2015-02-27 2018-04-17 Du Pont Construto de ácido ribonucleico, construto de dna, construto de expressão, cassete de expressão, célula hospedeira, composição, célula vegetal, planta ou parte de planta, semente transgênica, método para controlar um inseto- praga de planta, polinucleotídeo isolado e kit
WO2016174258A1 (en) 2015-04-29 2016-11-03 Boehringer Ingelheim Rcv Gmbh & Co Kg Means and methods for protein production
EP3362552A4 (en) * 2015-10-12 2019-04-24 Dow Agrosciences LLC WUPA-NUCLEIC ACID MOLECULES FOR THE AWARD OF RESISTANCE TO COLEOPTERA AND HEMIPTERA PESTS
AR109205A1 (es) 2016-08-05 2018-11-07 Syngenta Participations Ag Control de plagas de coleópteros utilizando moléculas de arn
AR109206A1 (es) 2016-08-05 2018-11-07 Syngenta Participations Ag Control de plagas de coleópteros utilizando moléculas de arn
US20190292543A1 (en) 2016-12-15 2019-09-26 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests

Also Published As

Publication number Publication date
BR112019002186A2 (pt) 2019-07-09
MX2022000736A (es) 2022-02-14
WO2018026770A2 (en) 2018-02-08
EP3494222A4 (en) 2020-08-19
US11945843B2 (en) 2024-04-02
RU2019105354A (ru) 2020-09-07
WO2018026770A3 (en) 2019-04-25
US20190185526A1 (en) 2019-06-20
EP4079857A3 (en) 2023-01-18
EP3494222A2 (en) 2019-06-12
RU2019105354A3 (es) 2020-12-11
EP4079857A2 (en) 2022-10-26
MX2019001292A (es) 2019-07-04
RU2022102484A (ru) 2022-03-16
CN109790544A (zh) 2019-05-21
CA3031143A1 (en) 2018-02-08

Similar Documents

Publication Publication Date Title
AR109205A1 (es) Control de plagas de coleópteros utilizando moléculas de arn
AR109207A1 (es) Control de plagas de coleópteros utilizando moléculas de arn
AR062019A1 (es) Gen de bacillus thuringiensis con actividad contra lepidopteros
AR090399A1 (es) Composiciones y metodos para incrementar la resistencia a nematodos en plantas
AR102251A1 (es) MOLÉCULAS DE ÁCIDO NUCLEICO DE SUBUNIDAD COPI COATOMER g QUE CONFIEREN UNA RESISTENCIA A LAS PLAGAS DE COLEÓPTEROS Y DE HEMÍPTEROS
NZ602352A (en) Toxin genes and methods for their use
AR040446A1 (es) Defensinas de plantas
AR055169A1 (es) Metodos para el control genetico de infestaciones de insectos en plantas y composiciones para los mismos
AR105838A1 (es) Proteínas inhibidoras de insectos
AR102300A1 (es) Proteínas tóxicas o inhibidoras de insectos lepidópteros
AR088263A1 (es) Moleculas de acido nucleico que se dirigen a rps6 y confieren resistencia a plagas de coleopteros
AR109206A1 (es) Control de plagas de coleópteros utilizando moléculas de arn
AR065283A1 (es) Composiciones y metodos que utilizan arn de interferencia del gen tipo opr3 para el control de nematodos
AR104833A1 (es) Composiciones y métodos para controlar plagas de plantas
ES2543203T3 (es) Grupo de genes NRPS-PKS, su manipulación y su utilidad
AR088261A1 (es) Moleculas de acido nucleico que se dirigen al gen pp1-87b y confieren resistencia a plagas de coleopteros
AR088113A1 (es) ARN DE INTERFERENCIA (ARNi) PARA EL CONTROL DE HONGOS Y OOMICETOS POR LA INHIBICION DEL GEN DE SACAROPINA DESHIDROGENASA
AR065282A1 (es) Composiciones y metodos que utilizan arn de transferencia de genes tipo cad para el control de nematodos
AR105155A1 (es) Composiciones y métodos para controlar plagas de plantas
AR110748A1 (es) Proteínas toxinas pesticidas activas contra insectos lepidópteros
AR060523A1 (es) Moleculas de polinucleotidos aislados que corresponden a alelos mutantes y tipo salvaje del gen de maiz d9 y metodos para usarlas
AR096405A2 (es) Molécula de ácido nucleico que confiere tolerancia al herbicida dicamba, métodos para producir plantas tolerantes a dicamba y para métodos para controlar el crecimiento de malezas
AR102762A1 (es) Secuencia de oligonucleótidos para uso en ingeniería de rutas metabólicas
Zukher et al. Reiterative synthesis by the ribosome and recognition of the N-terminal formyl group by biosynthetic machinery contribute to evolutionary conservation of the length of antibiotic microcin C peptide precursor
AR094337A1 (es) Método y composiciones para el control genético de insectos plaga en plantas de algodón a través del silenciamiento de genes de quitina sintasas