CA1095921A - Preparation of gamma-pyrones - Google Patents

Preparation of gamma-pyrones

Info

Publication number
CA1095921A
CA1095921A CA279,922A CA279922A CA1095921A CA 1095921 A CA1095921 A CA 1095921A CA 279922 A CA279922 A CA 279922A CA 1095921 A CA1095921 A CA 1095921A
Authority
CA
Canada
Prior art keywords
formula
pyran
process according
acid
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA279,922A
Other languages
English (en)
French (fr)
Inventor
Thomas M. Brennan
Donald E. Kuhla
Paul D. Weeks
Daniel P. Brannegan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Danisco Finland Oy
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/721,885 external-priority patent/US4082717A/en
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of CA1095921A publication Critical patent/CA1095921A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
CA279,922A 1976-08-02 1977-06-06 Preparation of gamma-pyrones Expired CA1095921A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US71090176A 1976-08-02 1976-08-02
US710-901 1976-08-02
US721,885 1976-09-09
US05/721,885 US4082717A (en) 1976-08-02 1976-09-09 Preparation of gamma-pyrones

Publications (1)

Publication Number Publication Date
CA1095921A true CA1095921A (en) 1981-02-17

Family

ID=27108548

Family Applications (3)

Application Number Title Priority Date Filing Date
CA279,922A Expired CA1095921A (en) 1976-08-02 1977-06-06 Preparation of gamma-pyrones
CA363,273A Expired CA1110254A (en) 1976-08-02 1980-10-24 Preparation of gamma-pyrones
CA000363274A Expired CA1117541A (en) 1976-08-02 1980-10-24 4-halo-dihydropyrans and the preparation thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
CA363,273A Expired CA1110254A (en) 1976-08-02 1980-10-24 Preparation of gamma-pyrones
CA000363274A Expired CA1117541A (en) 1976-08-02 1980-10-24 4-halo-dihydropyrans and the preparation thereof

Country Status (36)

Country Link
JP (7) JPS5318578A (es)
AR (1) AR216080A1 (es)
AT (3) AT362790B (es)
BE (1) BE855965A (es)
BG (4) BG28849A3 (es)
BR (1) BR7703970A (es)
CA (3) CA1095921A (es)
CH (4) CH625798A5 (es)
CS (3) CS203921B2 (es)
DD (1) DD132494A5 (es)
DE (3) DE2760221C2 (es)
DK (4) DK153483C (es)
EG (1) EG13080A (es)
ES (5) ES459994A1 (es)
FI (6) FI72722C (es)
FR (1) FR2372821A1 (es)
GB (5) GB1538375A (es)
GR (1) GR68938B (es)
HK (5) HK30481A (es)
HU (4) HU185687B (es)
IE (5) IE45643B1 (es)
IT (1) IT1106258B (es)
LU (1) LU77600A1 (es)
MX (1) MX4597E (es)
MY (3) MY8100262A (es)
NL (5) NL170955C (es)
NO (7) NO150561C (es)
NZ (1) NZ184342A (es)
PH (5) PH13557A (es)
PL (4) PL115497B1 (es)
PT (1) PT66694B (es)
RO (4) RO78953A (es)
SE (6) SE433079B (es)
SU (2) SU955859A3 (es)
TR (1) TR19652A (es)
YU (4) YU40166B (es)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008116301A1 (en) * 2007-03-28 2008-10-02 Apotex Technologies Inc. Fluorinated derivatives of deferiprone
US8703156B2 (en) 2008-04-25 2014-04-22 Apotex Technologies Inc. Liquid formulation for deferiprone with palatable taste
US9073865B2 (en) 2009-07-03 2015-07-07 Apotex Technologies Inc. Fluorinated derivates of 3-hydroxypyridin-4-ones

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1095921A (en) 1976-08-02 1981-02-17 Thomas M. Brennan Preparation of gamma-pyrones
FR2402654A1 (fr) * 1977-09-12 1979-04-06 Shinetsu Chemical Co Nouveaux derives de x tetrahydropyrannone(5)
JPS5444675A (en) * 1977-09-12 1979-04-09 Shin Etsu Chem Co Ltd Production of 3-hydroxy-4-pyrone analog
JPS5741226U (es) * 1980-08-20 1982-03-05
JPS59135008U (ja) * 1983-02-28 1984-09-10 松下電工株式会社 分電盤装置
JPS6050245A (ja) * 1983-08-29 1985-03-19 Nissan Motor Co Ltd 内燃機関の燃料噴射装置
JPH0226945Y2 (es) * 1985-09-11 1990-07-20
JP2586607B2 (ja) * 1987-10-30 1997-03-05 日産化学工業株式会社 光学活性アルコールの製造法
WO2017168309A1 (en) * 2016-03-29 2017-10-05 Dr. Reddy’S Laboratories Limited Process for preparation of eribulin and intermediates thereof
CN108609456B (zh) * 2016-12-13 2021-03-12 奥的斯电梯公司 可打开扩展面板及具有其的电梯吊顶，轿厢和系统
CN111606879A (zh) * 2020-05-25 2020-09-01 安徽金禾实业股份有限公司 一锅法制备2-羟甲基-3-烷氧基-4h-吡喃-4-酮的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3491122A (en) * 1966-09-14 1970-01-20 Monsanto Co Synthesis of 4-pyrones
US3547912A (en) * 1968-07-29 1970-12-15 American Home Prod Derivatives of 2h-pyran-3(6h)-ones and preparation thereof
JPS5145565B1 (es) * 1968-10-12 1976-12-04
US3621063A (en) * 1968-12-24 1971-11-16 Monsanto Co Unsaturated acyclic ketones
US3832357A (en) * 1971-05-26 1974-08-27 Daicel Ltd Process for preparation of 3-hydroxy-2-alkyl-4-pyrone
JPS5212166A (en) * 1975-07-17 1977-01-29 Tatsuya Shono Process for preparation of 4-pyron derivatives
IE42789B1 (en) * 1975-08-28 1980-10-22 Pfizer Preparation of gamma-pyrones
CA1095921A (en) * 1976-08-02 1981-02-17 Thomas M. Brennan Preparation of gamma-pyrones

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008116301A1 (en) * 2007-03-28 2008-10-02 Apotex Technologies Inc. Fluorinated derivatives of deferiprone
US8026261B2 (en) 2007-03-28 2011-09-27 Apotex Technologies Inc. Fluorinated derivatives of deferiprone
US8673943B2 (en) 2007-03-28 2014-03-18 Apotex Technologies Inc. Fluorinated derivatives of deferiprone
US8703156B2 (en) 2008-04-25 2014-04-22 Apotex Technologies Inc. Liquid formulation for deferiprone with palatable taste
US9073865B2 (en) 2009-07-03 2015-07-07 Apotex Technologies Inc. Fluorinated derivates of 3-hydroxypyridin-4-ones
US9550733B2 (en) 2009-07-03 2017-01-24 Apotex Technologies Inc. Fluorinated derivatives of 3-hydroxypyridin-4-ones
US9938240B2 (en) 2009-07-03 2018-04-10 Apotex Inc. Fluorinated derivatives of 3-hydroxypyridin-4-ones

Also Published As

Publication number Publication date
JPS5318578A (en) 1978-02-20
RO78953A (ro) 1982-04-12
YU43190B (en) 1989-04-30
DK326086D0 (da) 1986-07-09
GR68938B (es) 1982-03-29
FR2372821A1 (fr) 1978-06-30
FI72721B (fi) 1987-03-31
DE2728499A1 (de) 1978-02-09
BG28988A4 (en) 1980-08-15
EG13080A (en) 1981-03-31
SE8200520L (sv) 1982-01-29
JPS5618596B2 (es) 1981-04-30
NO150559C (no) 1984-11-07
IE45643B1 (en) 1982-10-20
DK326186A (da) 1986-07-09
DK154079C (da) 1989-02-27
FI831703A0 (fi) 1983-05-16
DK325986D0 (da) 1986-07-09
PT66694A (en) 1977-07-01
HK30481A (en) 1981-07-10
NL182477B (nl) 1987-10-16
NO150043C (no) 1984-08-15
RO78951A2 (ro) 1982-04-12
FI72119C (fi) 1987-04-13
NL8105538A (nl) 1982-04-01
PH14625A (en) 1981-10-12
NO821848L (no) 1978-02-03
ATA124380A (de) 1981-03-15
MX4597E (es) 1982-06-25
DK153483B (da) 1988-07-18
DK153483C (da) 1988-11-28
NO150559B (no) 1984-07-30
AR216080A1 (es) 1979-11-30
BG28989A4 (en) 1980-08-15
DK153484B (da) 1988-07-18
DK154079B (da) 1988-10-10
FI831704L (fi) 1983-05-16
NL182478B (nl) 1987-10-16
JPS5814433B2 (ja) 1983-03-18
CS203923B2 (en) 1981-03-31
NL182805B (nl) 1987-12-16
RO74367A (ro) 1981-11-24
NL170955C (nl) 1983-01-17
IE790586L (en) 1978-02-02
NL8105537A (nl) 1982-04-01
NL170955B (nl) 1982-08-16
DK153484C (da) 1988-11-28
CH625798A5 (en) 1981-10-15
IE45644B1 (en) 1982-10-20
SE8200519L (sv) 1982-01-29
SE445042B (sv) 1986-05-26
IE45641L (en) 1978-02-02
FI831702L (fi) 1983-05-16
PL199798A1 (pl) 1979-08-27
NO150561C (no) 1984-11-07
TR19652A (tr) 1979-09-17
PL115496B1 (en) 1981-04-30
JPS5436266A (en) 1979-03-16
FI72723B (fi) 1987-03-31
YU42613B (en) 1988-10-31
CH626357A5 (en) 1981-11-13
ES459994A1 (es) 1978-11-16
MY8100262A (en) 1981-12-31
JPS5436271A (en) 1979-03-16
NO150560B (no) 1984-07-30
NL7706811A (nl) 1978-02-06
RO78952A (ro) 1982-04-12
FI831702A0 (fi) 1983-05-16
LU77600A1 (es) 1978-02-01
NO150560C (no) 1984-11-07
HU186026B (en) 1985-05-28
BR7703970A (pt) 1978-07-04
HU180040B (en) 1983-01-28
NO821851L (no) 1978-02-03
AT364356B (de) 1981-10-12
NL8105539A (nl) 1982-04-01
IT1106258B (it) 1985-11-11
IE790584L (en) 1978-02-02
YU40166B (en) 1985-08-31
SE445041B (sv) 1986-05-26
BG28849A3 (en) 1980-07-15
NO821849L (no) 1978-02-03
DK153401C (da) 1988-11-28
IE45641B1 (en) 1982-10-20
CA1110254A (en) 1981-10-06
DD132494A5 (de) 1978-10-04
PH13557A (en) 1980-06-26
NL182478C (nl) 1988-03-16
PL115586B1 (en) 1981-04-30
NO821847L (no) 1978-02-03
BG29136A3 (en) 1980-09-15
HU185687B (en) 1985-03-28
SE444564B (sv) 1986-04-21
NL182476B (nl) 1987-10-16
DK325986A (da) 1986-07-09
GB1538374A (en) 1979-01-17
HU185686B (en) 1985-03-28
HK30581A (en) 1981-07-10
FI72722C (fi) 1987-07-10
PL215006A1 (pl) 1979-12-17
ES470746A1 (es) 1979-01-16
ATA440477A (de) 1980-11-15
SE8200522L (sv) 1982-01-29
HK30681A (en) 1981-07-10
JPS5618597B2 (es) 1981-04-30
SE8200521L (sv) 1982-01-29
JPS5436270A (en) 1979-03-16
SE433079B (sv) 1984-05-07
SE452616B (sv) 1987-12-07
FI73424C (fi) 1987-10-09
NO150043B (no) 1984-04-30
SU955859A3 (ru) 1982-08-30
FI831701A0 (fi) 1983-05-16
IE790585L (en) 1978-02-02
PH15185A (en) 1982-09-10
YU166383A (en) 1986-02-28
FI831704A0 (fi) 1983-05-16
NZ184342A (en) 1978-09-25
NL8105540A (nl) 1982-04-01
NO772193L (no) 1978-02-03
FR2372821B1 (es) 1980-10-17
FI72119B (fi) 1986-12-31
DE2760221C2 (es) 1989-10-05
HK30781A (en) 1981-07-10
NO821850L (no) 1978-02-03
SE444565B (sv) 1986-04-21
IE790587L (en) 1978-02-02
HK30381A (en) 1981-07-10
NO150042B (no) 1984-04-30
JPS5436267A (en) 1979-03-16
NO150561B (no) 1984-07-30
NO151365B (no) 1984-12-17
PL215007A1 (pl) 1979-12-17
ES470743A1 (es) 1979-01-16
AT363470B (de) 1981-08-10
PH13926A (en) 1980-11-04
FI72720C (fi) 1987-07-10
GB1538373A (en) 1979-01-17
PL215008A1 (pl) 1979-12-17
JPS5436268A (en) 1979-03-16
NL182805C (nl) 1988-05-16
PH13874A (en) 1980-10-24
IE45642B1 (en) 1982-10-20
ES470744A1 (es) 1979-01-16
FI72721C (fi) 1987-07-10
DE2760220C2 (es) 1987-08-20
FI831701L (fi) 1983-05-16
CS203921B2 (en) 1981-03-31
DK326186D0 (da) 1986-07-09
FI771934A (es) 1978-02-03
DK153401B (da) 1988-07-11
DK326086A (da) 1986-07-09
CA1117541A (en) 1982-02-02
FI72722B (fi) 1987-03-31
NL182476C (nl) 1988-03-16
FI831703L (fi) 1983-05-16
DE2728499C2 (de) 1986-04-03
MY8100287A (en) 1981-12-31
ATA124480A (de) 1981-01-15
FI73424B (fi) 1987-06-30
IE45645B1 (en) 1982-10-20
CS203922B2 (en) 1981-03-31
JPS5729034B2 (es) 1982-06-19
BE855965A (fr) 1977-12-21
PL115497B1 (en) 1981-04-30
NO150042C (no) 1984-08-15
PT66694B (en) 1978-11-17
MY8100267A (en) 1981-12-31
JPS5436269A (en) 1979-03-16
CH625235A5 (en) 1981-09-15
YU270382A (en) 1983-10-31
SE7707035L (sv) 1978-02-03
CH626358A5 (en) 1981-11-13
FI72720B (fi) 1987-03-31
AU2601777A (en) 1978-09-21
GB1538372A (en) 1979-01-17
FI831700L (fi) 1983-05-16
NL182477C (nl) 1988-03-16
SE8200518L (sv) 1982-01-29
FI831700A0 (fi) 1983-05-16
YU274782A (en) 1983-12-31
FI72723C (fi) 1987-07-10
YU146977A (en) 1983-06-30
ES470745A1 (es) 1979-01-16
SU1015826A3 (ru) 1983-04-30
JPS5420500B2 (es) 1979-07-23
DK276177A (da) 1978-02-03
AT362790B (de) 1981-06-10
GB1538371A (en) 1979-01-17
GB1538375A (en) 1979-01-17
NO834236L (no) 1978-02-03
NO151365C (no) 1985-03-27

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Legal Events

Date Code Title Description
MKEX Expiry