BR112018071026B1 - Polímero fluorescente solúvel em água e método para detectar um analito de uma amostra - Google Patents

Polímero fluorescente solúvel em água e método para detectar um analito de uma amostra Download PDF

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Publication number
BR112018071026B1
BR112018071026B1 BR112018071026-1A BR112018071026A BR112018071026B1 BR 112018071026 B1 BR112018071026 B1 BR 112018071026B1 BR 112018071026 A BR112018071026 A BR 112018071026A BR 112018071026 B1 BR112018071026 B1 BR 112018071026B1
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polymer
group
independently
hetero
independently selected
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BR112018071026-1A
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Portuguese (pt)
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BR112018071026A2 (pt
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Arunkumar Easwaran
Sergei Gulnik
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Beckman Coulter, Inc
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    • C08G61/12—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule
    • C08G61/122—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides
    • C08G61/123—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides derived from five-membered heterocyclic compounds
    • C08G61/126—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides derived from five-membered heterocyclic compounds with a five-membered ring containing one sulfur atom in the ring
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    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/06—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials
    • G—PHYSICS
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • C08G2261/1424—Side-chains containing oxygen containing ether groups, including alkoxy
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  • Polymers & Plastics (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Polyethers (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Materials For Medical Uses (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
BR112018071026-1A 2016-04-15 2017-04-14 Polímero fluorescente solúvel em água e método para detectar um analito de uma amostra BR112018071026B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662323444P 2016-04-15 2016-04-15
US62/323,444 2016-04-15
PCT/US2017/027611 WO2017180998A2 (en) 2016-04-15 2017-04-14 Photoactive macromolecules and uses thereof

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BR112018071026A2 BR112018071026A2 (pt) 2019-02-12
BR112018071026B1 true BR112018071026B1 (pt) 2023-04-11

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US (3) US11208527B2 (https=)
EP (5) EP4407013B1 (https=)
JP (6) JP6882331B2 (https=)
KR (5) KR102836360B1 (https=)
CN (3) CN113801296B (https=)
AU (3) AU2017250778B2 (https=)
BR (1) BR112018071026B1 (https=)
CA (1) CA3020926C (https=)
ES (4) ES3046711T3 (https=)
WO (1) WO2017180998A2 (https=)

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AU2017250778B2 (en) 2016-04-15 2021-09-23 Beckman Coulter, Inc. Photoactive macromolecules and uses thereof
JP7097885B2 (ja) 2016-12-12 2022-07-08 ベクトン・ディキンソン・アンド・カンパニー 水溶性ポリマー色素
CN119286279A (zh) 2017-12-26 2025-01-10 贝克顿·迪金森公司 深紫外线可激发的水溶剂化聚合物染料
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JP2021533240A (ja) * 2018-08-07 2021-12-02 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company ペンダント狭発光アクセプタを有するポリマータンデム色素
WO2020106361A2 (en) 2018-09-21 2020-05-28 Joshua Tropp Thiol-based post-modification of conjugated polymers
US11584825B2 (en) 2018-12-14 2023-02-21 Beckman Coulter, Inc. Polymer dye modification and applications
US11781986B2 (en) 2019-12-31 2023-10-10 University Of Southern Mississippi Methods for detecting analytes using conjugated polymers and the inner filter effect
EP3916393B1 (en) * 2020-05-27 2023-01-25 Miltenyi Biotec B.V. & Co. KG Method for detection of cells by repetitive staining and destaining
AU2022216619A1 (en) 2021-02-05 2023-09-07 Beckman Coulter, Inc. Compositions and methods for preventing non-specific interactions between polymer dyes-antibody conjugates
CN117255832A (zh) * 2021-05-04 2023-12-19 贝克曼库尔特有限公司 紫外吸收聚合物、组合物及其用途
AU2022269592A1 (en) 2021-05-04 2023-10-05 Beckman Coulter, Inc. Uv-absorbing polymers, compositions and uses thereof
US20240400893A1 (en) 2021-09-30 2024-12-05 Beckman Coulter, Inc. Water-soluble tetrahydropyrene based fluorescent polymers
CA3237877A1 (en) 2021-11-12 2023-05-19 Aditya JARARE Novel formulation for drying of polymer dye conjugated antibodies
US20250383357A1 (en) 2022-07-01 2025-12-18 Beckman Coulter, Inc. Novel fluorescent dyes and polymers from dihydrophenanthrene derivatives
WO2024044327A1 (en) 2022-08-26 2024-02-29 Beckman Coulter, Inc. Dhnt monomers and polymer dyes with modified photophysical properties
EP4680677A1 (en) 2023-03-17 2026-01-21 Beckman Coulter, Inc. Benzothienopyrrole cyanine dyes
CN121866309A (zh) 2023-09-21 2026-04-14 贝克曼库尔特有限公司 用于流式细胞术的二氢菲（dhp）桥接染料

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