AU2017250778B2 - Photoactive macromolecules and uses thereof - Google Patents

Photoactive macromolecules and uses thereof Download PDF

Info

Publication number
AU2017250778B2
AU2017250778B2 AU2017250778A AU2017250778A AU2017250778B2 AU 2017250778 B2 AU2017250778 B2 AU 2017250778B2 AU 2017250778 A AU2017250778 A AU 2017250778A AU 2017250778 A AU2017250778 A AU 2017250778A AU 2017250778 B2 AU2017250778 B2 AU 2017250778B2
Authority
AU
Australia
Prior art keywords
polymer
group
peg
hetero
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2017250778A
Other languages
English (en)
Other versions
AU2017250778A1 (en
Inventor
Arunkumar Easwaran
Sergei Gulnik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Publication of AU2017250778A1 publication Critical patent/AU2017250778A1/en
Priority to AU2021212098A priority Critical patent/AU2021212098B9/en
Application granted granted Critical
Publication of AU2017250778B2 publication Critical patent/AU2017250778B2/en
Priority to AU2023203991A priority patent/AU2023203991B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G61/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G61/02—Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G61/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G61/12—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule
    • C08G61/122—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides
    • C08G61/123—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides derived from five-membered heterocyclic compounds
    • C08G61/126—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides derived from five-membered heterocyclic compounds with a five-membered ring containing one sulfur atom in the ring
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B69/00—Dyes not provided for by a single group of this subclass
    • C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G61/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G61/12—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule
    • C08G61/122—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides
    • C08G61/123—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides derived from five-membered heterocyclic compounds
    • C08G61/124—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides derived from five-membered heterocyclic compounds with a five-membered ring containing one nitrogen atom in the ring
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/06—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/10—Definition of the polymer structure
    • C08G2261/11—Homopolymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/10—Definition of the polymer structure
    • C08G2261/12—Copolymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/10—Definition of the polymer structure
    • C08G2261/12—Copolymers
    • C08G2261/124—Copolymers alternating
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/10—Definition of the polymer structure
    • C08G2261/14—Side-groups
    • C08G2261/142—Side-chains containing oxygen
    • C08G2261/1424—Side-chains containing oxygen containing ether groups, including alkoxy
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/10—Definition of the polymer structure
    • C08G2261/14—Side-groups
    • C08G2261/143—Side-chains containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/10—Definition of the polymer structure
    • C08G2261/14—Side-groups
    • C08G2261/145—Side-chains containing sulfur
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/10—Definition of the polymer structure
    • C08G2261/14—Side-groups
    • C08G2261/145—Side-chains containing sulfur
    • C08G2261/1452—Side-chains containing sulfur containing sulfonyl or sulfonate-groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/10—Definition of the polymer structure
    • C08G2261/16—End groups
    • C08G2261/164—End groups comprising organic end groups
    • C08G2261/1644—End groups comprising organic end groups comprising other functional groups, e.g. OH groups, NH groups, COOH groups or boronic acid
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/10—Definition of the polymer structure
    • C08G2261/16—End groups
    • C08G2261/164—End groups comprising organic end groups
    • C08G2261/1646—End groups comprising organic end groups comprising aromatic or heteroaromatic end groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/30—Monomer units or repeat units incorporating structural elements in the main chain
    • C08G2261/31—Monomer units or repeat units incorporating structural elements in the main chain incorporating aromatic structural elements in the main chain
    • C08G2261/314—Condensed aromatic systems, e.g. perylene, anthracene or pyrene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/30—Monomer units or repeat units incorporating structural elements in the main chain
    • C08G2261/31—Monomer units or repeat units incorporating structural elements in the main chain incorporating aromatic structural elements in the main chain
    • C08G2261/314—Condensed aromatic systems, e.g. perylene, anthracene or pyrene
    • C08G2261/3142—Condensed aromatic systems, e.g. perylene, anthracene or pyrene fluorene-based, e.g. fluorene, indenofluorene, or spirobifluorene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/30—Monomer units or repeat units incorporating structural elements in the main chain
    • C08G2261/33—Monomer units or repeat units incorporating structural elements in the main chain incorporating non-aromatic structural elements in the main chain
    • C08G2261/332—Monomer units or repeat units incorporating structural elements in the main chain incorporating non-aromatic structural elements in the main chain containing only carbon atoms
    • C08G2261/3327—Monomer units or repeat units incorporating structural elements in the main chain incorporating non-aromatic structural elements in the main chain containing only carbon atoms alkene-based
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/30—Monomer units or repeat units incorporating structural elements in the main chain
    • C08G2261/34—Monomer units or repeat units incorporating structural elements in the main chain incorporating partially-aromatic structural elements in the main chain
    • C08G2261/342—Monomer units or repeat units incorporating structural elements in the main chain incorporating partially-aromatic structural elements in the main chain containing only carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/40—Polymerisation processes
    • C08G2261/41—Organometallic coupling reactions
    • C08G2261/411—Suzuki reactions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/50—Physical properties
    • C08G2261/52—Luminescence
    • C08G2261/522—Luminescence fluorescent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/90—Applications
    • C08G2261/94—Applications in sensors, e.g. biosensors
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/14—Macromolecular compounds
    • C09K2211/1408—Carbocyclic compounds
    • C09K2211/1416—Condensed systems
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/14—Macromolecular compounds
    • C09K2211/1441—Heterocyclic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Polyethers (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Materials For Medical Uses (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AU2017250778A 2016-04-15 2017-04-14 Photoactive macromolecules and uses thereof Active AU2017250778B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2021212098A AU2021212098B9 (en) 2016-04-15 2021-08-06 Photoactive macromolecules and uses thereof
AU2023203991A AU2023203991B2 (en) 2016-04-15 2023-06-23 Photoactive macromolecules and uses thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662323444P 2016-04-15 2016-04-15
US62/323,444 2016-04-15
PCT/US2017/027611 WO2017180998A2 (en) 2016-04-15 2017-04-14 Photoactive macromolecules and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2021212098A Division AU2021212098B9 (en) 2016-04-15 2021-08-06 Photoactive macromolecules and uses thereof

Publications (2)

Publication Number Publication Date
AU2017250778A1 AU2017250778A1 (en) 2018-11-01
AU2017250778B2 true AU2017250778B2 (en) 2021-09-23

Family

ID=59297339

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2017250778A Active AU2017250778B2 (en) 2016-04-15 2017-04-14 Photoactive macromolecules and uses thereof
AU2021212098A Active AU2021212098B9 (en) 2016-04-15 2021-08-06 Photoactive macromolecules and uses thereof
AU2023203991A Active AU2023203991B2 (en) 2016-04-15 2023-06-23 Photoactive macromolecules and uses thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2021212098A Active AU2021212098B9 (en) 2016-04-15 2021-08-06 Photoactive macromolecules and uses thereof
AU2023203991A Active AU2023203991B2 (en) 2016-04-15 2023-06-23 Photoactive macromolecules and uses thereof

Country Status (10)

Country Link
US (3) US11208527B2 (https=)
EP (5) EP4407013B1 (https=)
JP (6) JP6882331B2 (https=)
KR (5) KR102836360B1 (https=)
CN (3) CN113801296B (https=)
AU (3) AU2017250778B2 (https=)
BR (1) BR112018071026B1 (https=)
CA (1) CA3020926C (https=)
ES (4) ES3046711T3 (https=)
WO (1) WO2017180998A2 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022104147A1 (en) 2020-11-13 2022-05-19 Beckman Coulter, Inc. Additives for reducing non-specific interactions between fluorescent polymer conjugates and cells in a biological sample
AU2017250778B2 (en) 2016-04-15 2021-09-23 Beckman Coulter, Inc. Photoactive macromolecules and uses thereof
JP7097885B2 (ja) 2016-12-12 2022-07-08 ベクトン・ディキンソン・アンド・カンパニー 水溶性ポリマー色素
CN119286279A (zh) 2017-12-26 2025-01-10 贝克顿·迪金森公司 深紫外线可激发的水溶剂化聚合物染料
US11773211B2 (en) 2018-05-05 2023-10-03 University Of Southern Mississippi Open-shell conjugated polymer conductors, composites, and compositions
JP2021533240A (ja) * 2018-08-07 2021-12-02 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company ペンダント狭発光アクセプタを有するポリマータンデム色素
WO2020106361A2 (en) 2018-09-21 2020-05-28 Joshua Tropp Thiol-based post-modification of conjugated polymers
US11584825B2 (en) 2018-12-14 2023-02-21 Beckman Coulter, Inc. Polymer dye modification and applications
US11781986B2 (en) 2019-12-31 2023-10-10 University Of Southern Mississippi Methods for detecting analytes using conjugated polymers and the inner filter effect
EP3916393B1 (en) * 2020-05-27 2023-01-25 Miltenyi Biotec B.V. & Co. KG Method for detection of cells by repetitive staining and destaining
AU2022216619A1 (en) 2021-02-05 2023-09-07 Beckman Coulter, Inc. Compositions and methods for preventing non-specific interactions between polymer dyes-antibody conjugates
CN117255832A (zh) * 2021-05-04 2023-12-19 贝克曼库尔特有限公司 紫外吸收聚合物、组合物及其用途
AU2022269592A1 (en) 2021-05-04 2023-10-05 Beckman Coulter, Inc. Uv-absorbing polymers, compositions and uses thereof
US20240400893A1 (en) 2021-09-30 2024-12-05 Beckman Coulter, Inc. Water-soluble tetrahydropyrene based fluorescent polymers
CA3237877A1 (en) 2021-11-12 2023-05-19 Aditya JARARE Novel formulation for drying of polymer dye conjugated antibodies
US20250383357A1 (en) 2022-07-01 2025-12-18 Beckman Coulter, Inc. Novel fluorescent dyes and polymers from dihydrophenanthrene derivatives
WO2024044327A1 (en) 2022-08-26 2024-02-29 Beckman Coulter, Inc. Dhnt monomers and polymer dyes with modified photophysical properties
EP4680677A1 (en) 2023-03-17 2026-01-21 Beckman Coulter, Inc. Benzothienopyrrole cyanine dyes
CN121866309A (zh) 2023-09-21 2026-04-14 贝克曼库尔特有限公司 用于流式细胞术的二氢菲（dhp）桥接染料

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011091086A1 (en) * 2010-01-19 2011-07-28 Sirigen Inc. Novel reagents for directed biomarker signal amplification

Family Cites Families (238)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL96874C (https=) 1954-04-03
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4486530A (en) 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4703004A (en) 1984-01-24 1987-10-27 Immunex Corporation Synthesis of protein with an identification peptide
DE3408028A1 (de) 1984-03-05 1985-09-12 Kernforschungszentrum Karlsruhe Gmbh, 7500 Karlsruhe Verwendung von substituierten und unsubstituierten ringueberbrueckten para-oligophenylenen als uv-laserfarbstoffe
US6086737A (en) 1984-03-29 2000-07-11 Li-Cor, Inc. Sequencing near infrared and infrared fluorescence labeled DNA for detecting using laser diodes and suitable labels therefor
GB8504702D0 (en) 1985-02-23 1985-03-27 Zyma Sa Tricyclic compounds
DE3815826A1 (de) 1988-05-09 1989-11-23 Henkel Kgaa Verfahren zur herstellung von vicinal diacyloxysubstituierten verbindungen
US5470829A (en) 1988-11-17 1995-11-28 Prisell; Per Pharmaceutical preparation
WO1990006952A1 (fr) 1988-12-22 1990-06-28 Kirin-Amgen, Inc. Facteur de stimulation de colonies de granulocytes modifies chimiquement
US5089261A (en) 1989-01-23 1992-02-18 Cetus Corporation Preparation of a polymer/interleukin-2 conjugate
US5122614A (en) 1989-04-19 1992-06-16 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
ES2136595T5 (es) 1989-04-19 2004-04-01 Enzon, Inc. Carbonatos activos de oxidos de polialquileno para la modificacion de polipeptidos.
US5324844A (en) 1989-04-19 1994-06-28 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
IL90193A (en) 1989-05-04 1993-02-21 Biomedical Polymers Int Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same
JP3010067B2 (ja) * 1989-09-06 2000-02-14 トロピックス・インコーポレーテッド 安定で水溶性の化学発光性１、２―ジオキセタンおよびそれらの中間体の合成法
US5225584A (en) 1989-09-06 1993-07-06 Tropix, Inc. Synthesis of stable water-soluble chemiluminescent 1,2-dioxetanes and intermediates therefor
US5650388A (en) 1989-11-22 1997-07-22 Enzon, Inc. Fractionated polyalkylene oxide-conjugated hemoglobin solutions
US5312808A (en) 1989-11-22 1994-05-17 Enzon, Inc. Fractionation of polyalkylene oxide-conjugated hemoglobin solutions
NL194941C (nl) 1990-02-15 2003-08-04 Cordis Corp Werkwijze voor het aanbrengen van een fysiologisch actieve verbinding op een substraatoppervlak.
US5171264A (en) 1990-02-28 1992-12-15 Massachusetts Institute Of Technology Immobilized polyethylene oxide star molecules for bioapplications
US5275838A (en) 1990-02-28 1994-01-04 Massachusetts Institute Of Technology Immobilized polyethylene oxide star molecules for bioapplications
US5723218A (en) 1990-04-16 1998-03-03 Molecular Probes, Inc. Dipyrrometheneboron difluoride labeled flourescent microparticles
US5326692B1 (en) 1992-05-13 1996-04-30 Molecular Probes Inc Fluorescent microparticles with controllable enhanced stokes shift
US5219564A (en) 1990-07-06 1993-06-15 Enzon, Inc. Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
WO1992000748A1 (en) 1990-07-06 1992-01-23 Enzon, Inc. Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
FR2672053B1 (fr) 1991-01-30 1993-04-23 Atochem Polyether bloc amides, leur procede de synthese.
FR2673946B1 (fr) 1991-03-15 1993-05-28 Atochem Polyether bloc amides, leur procede de synthese.
JPH06506217A (ja) 1991-03-18 1994-07-14 エンゾン，インコーポレーテッド ポリペプチドまたはグリコポリペプチドとポリマーとのヒドラジン含有結合体
US5187288A (en) 1991-05-22 1993-02-16 Molecular Probes, Inc. Ethenyl-substituted dipyrrometheneboron difluoride dyes and their synthesis
US5281698A (en) 1991-07-23 1994-01-25 Cetus Oncology Corporation Preparation of an activated polymer ester for protein conjugation
US5576424A (en) 1991-08-23 1996-11-19 Molecular Probes, Inc. Haloalkyl derivatives of reporter molecules used to analyze metabolic activity in cells
CA2119126C (en) 1991-09-16 1996-09-03 Molecular Probes, Inc. Dimers of unsymmetrical cyanine dyes
AU660534B2 (en) 1992-02-13 1995-06-29 Novo Nordisk A/S Polyethylene or polypropylene glycol containing polymer
AU5006993A (en) 1992-08-21 1994-03-15 Enzon, Inc. Novel attachment of polyalkylene oxides to bio-effecting substances
US5614549A (en) 1992-08-21 1997-03-25 Enzon, Inc. High molecular weight polymer-based prodrugs
US5298643A (en) 1992-12-22 1994-03-29 Enzon, Inc. Aryl imidate activated polyalkylene oxides
US5349001A (en) 1993-01-19 1994-09-20 Enzon, Inc. Cyclic imide thione activated polyalkylene oxides
US5321095A (en) 1993-02-02 1994-06-14 Enzon, Inc. Azlactone activated polyalkylene oxides
US5658751A (en) 1993-04-13 1997-08-19 Molecular Probes, Inc. Substituted unsymmetrical cyanine dyes with selected permeability
AU7109494A (en) 1993-06-16 1995-01-03 Enzon, Inc. Conjugated biodhesives
US5965566A (en) 1993-10-20 1999-10-12 Enzon, Inc. High molecular weight polymer-based prodrugs
US5880131A (en) 1993-10-20 1999-03-09 Enzon, Inc. High molecular weight polymer-based prodrugs
US5840900A (en) 1993-10-20 1998-11-24 Enzon, Inc. High molecular weight polymer-based prodrugs
US5919455A (en) 1993-10-27 1999-07-06 Enzon, Inc. Non-antigenic branched polymer conjugates
US5643575A (en) 1993-10-27 1997-07-01 Enzon, Inc. Non-antigenic branched polymer conjugates
US5605976A (en) 1995-05-15 1997-02-25 Enzon, Inc. Method of preparing polyalkylene oxide carboxylic acids
US5446090A (en) 1993-11-12 1995-08-29 Shearwater Polymers, Inc. Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
US5618528A (en) 1994-02-28 1997-04-08 Sterling Winthrop Inc. Biologically compatible linear block copolymers of polyalkylene oxide and peptide units
AU2826495A (en) 1994-06-02 1996-01-04 Enzon, Inc. Method of solubilizing substantially water insoluble materials
US5730990A (en) 1994-06-24 1998-03-24 Enzon, Inc. Non-antigenic amine derived polymers and polymer conjugates
US5453505A (en) 1994-06-30 1995-09-26 Biometric Imaging, Inc. N-heteroaromatic ion and iminium ion substituted cyanine dyes for use as fluorescence labels
DE4431039A1 (de) 1994-09-01 1996-03-07 Hoechst Ag Poly(4,5,9,10-tetrahydropyren-2,7-diyl)-Derivate und ihre Verwendung als Elektrolumineszenzmaterialien
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
US5932462A (en) 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
US5656449A (en) 1995-03-06 1997-08-12 Molecular Probes, Inc. Neutral unsymmetrical cyanine dyes
US5756593A (en) 1995-05-15 1998-05-26 Enzon, Inc. Method of preparing polyalkyene oxide carboxylic acids
US5798276A (en) 1995-06-07 1998-08-25 Molecular Probes, Inc. Reactive derivatives of sulforhodamine 101 with enhanced hydrolytic stability
US6596522B2 (en) 1997-05-08 2003-07-22 The Regents Of The University Of California Detection of transmembrane potentials by optical methods
US5672662A (en) 1995-07-07 1997-09-30 Shearwater Polymers, Inc. Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
CA2226299A1 (en) 1995-08-11 1997-02-27 Dendritech, Inc. Hyper comb-branched polymer conjugates
US6004536A (en) 1995-11-14 1999-12-21 Molecular Probes, Inc. Lipophilic cyanine dyes with enchanced aqueous solubilty
WO1997022371A1 (en) 1995-12-18 1997-06-26 Collagen Corporation Crosslinked polymer compositions and methods for their use
US6162931A (en) 1996-04-12 2000-12-19 Molecular Probes, Inc. Fluorinated xanthene derivatives
US6005113A (en) 1996-05-15 1999-12-21 Molecular Probes, Inc. Long wavelength dyes for infrared tracing
US5846737A (en) 1996-07-26 1998-12-08 Molecular Probes, Inc. Conjugates of sulforhodamine fluorophores with enhanced fluorescence
EP0964702B1 (en) 1996-08-02 2006-10-04 Ortho-McNeil Pharmaceutical, Inc. Polypeptides having a single covalently bound n-terminal water-soluble polymer
US6214966B1 (en) 1996-09-26 2001-04-10 Shearwater Corporation Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
US5696157A (en) 1996-11-15 1997-12-09 Molecular Probes, Inc. Sulfonated derivatives of 7-aminocoumarin
EP0979102A4 (en) 1997-04-30 2005-11-23 Enzon Inc DETAILED POLYPEPTIDE MODIFIED BY POLYALKYLENE OXIDE
WO1998051757A1 (en) 1997-05-15 1998-11-19 Sanyo Electric Co., Ltd. Organic electroluminescence element
US5990237A (en) 1997-05-21 1999-11-23 Shearwater Polymers, Inc. Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines
US6130101A (en) 1997-09-23 2000-10-10 Molecular Probes, Inc. Sulfonated xanthene derivatives
US6011042A (en) 1997-10-10 2000-01-04 Enzon, Inc. Acyl polymeric derivatives of aromatic hydroxyl-containing compounds
US6322901B1 (en) 1997-11-13 2001-11-27 Massachusetts Institute Of Technology Highly luminescent color-selective nano-crystalline materials
US6111107A (en) 1997-11-20 2000-08-29 Enzon, Inc. High yield method for stereoselective acylation of tertiary alcohols
US5990479A (en) 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
WO1999030727A1 (en) 1997-12-17 1999-06-24 Enzon, Inc. Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
US6180095B1 (en) 1997-12-17 2001-01-30 Enzon, Inc. Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
US5985263A (en) 1997-12-19 1999-11-16 Enzon, Inc. Substantially pure histidine-linked protein polymer conjugates
US5965119A (en) 1997-12-30 1999-10-12 Enzon, Inc. Trialkyl-lock-facilitated polymeric prodrugs of amino-containing bioactive agents
JP4078032B2 (ja) 1998-03-12 2008-04-23 ネクター セラピューティックス エイエル，コーポレイション 近位の反応性基を持つポリ（エチレングリコール）誘導体
US6153655A (en) 1998-04-17 2000-11-28 Enzon, Inc. Terminally-branched polymeric linkers and polymeric conjugates containing the same
JP2000063690A (ja) 1998-08-21 2000-02-29 Konica Corp 新規化合物、それを含有するハロゲン化銀乳剤、ハロゲン化銀感光材料、熱現像銀塩写真感光材料、光記録媒体及び画像形成方法
JP2002528723A (ja) 1998-10-27 2002-09-03 モレキュラー・プロウブズ・インコーポレーテッド 遷移金属錯体を含有する発光タンパク質染色剤
WO2000064988A1 (en) 1999-04-23 2000-11-02 Molecular Probes, Inc. Xanthene dyes and their application as luminescence quenching compounds
TW484341B (en) 1999-08-03 2002-04-21 Sumitomo Chemical Co Polymeric fluorescent substance and polymer light emitting device
JP4605412B2 (ja) 1999-08-27 2011-01-05 Ｄｉｃ株式会社 フェナントレン及びフルオレン誘導体
DK1455839T3 (da) 1999-10-08 2013-05-06 Nektar Therapeutics Heterobifunktioneller poly(ethylenglycol)-derivater og fremgangsmåder til fremstilling heraf
US7102024B1 (en) * 2000-08-01 2006-09-05 Schwartz David A Functional biopolymer modification reagents and uses thereof
US6579718B1 (en) 2000-08-04 2003-06-17 Molecular Probes, Inc. Carbazolylvinyl dye protein stains
EP1311487B1 (en) 2000-08-04 2008-11-26 Molecular Probes, Inc. Derivatives of 1,2-dihydro-7-hydroxyquinolines containing fused rings
CA2423806C (en) 2000-09-29 2009-12-22 Molecular Probes, Inc. Modified carbocyanine dyes and their conjugates
KR100865775B1 (ko) 2000-11-20 2008-10-29 메르크 파텐트 게엠베하 키랄 광이성질성 화합물
US6972326B2 (en) 2001-12-03 2005-12-06 Molecular Probes, Inc. Labeling of immobilized proteins using dipyrrometheneboron difluoride dyes
CA2365814C (en) 2001-12-21 2009-05-12 American Dye Source, Inc. Photoluminescent markers and methods for detection of such markers
SE0201468D0 (sv) 2002-05-13 2002-05-13 Peter Aasberg Metod att använda luminescenta polymerer för detektion av biospecifik växelverkan
US9371559B2 (en) 2002-06-20 2016-06-21 The Regents Of The University Of California Compositions for detection and analysis of polynucleotides using light harvesting multichromophores
US7144950B2 (en) 2003-09-17 2006-12-05 The Regents Of The University Of California Conformationally flexible cationic conjugated polymers
CN1675377B (zh) 2002-06-20 2012-10-03 加州大学评议会 利用获取光的多发色团检测和分析多核苷酸的方法和组合物
US10001475B2 (en) 2002-06-20 2018-06-19 The Regents Of The University Of California Light harvesting multichromophore compositions and methods of using the same
BR0312780A (pt) 2002-07-19 2005-05-03 Pharmacia Corp Compostos de tiofeno-carboxamida substituìda para o tratamento de inflamação
US6562982B1 (en) 2002-07-25 2003-05-13 Xerox Corporation Carbazole compounds
US6670054B1 (en) 2002-07-25 2003-12-30 Xerox Corporation Electroluminescent devices
US20040101909A1 (en) 2002-08-20 2004-05-27 Hema-Quebec, 2535 Boul. Laurier, Ste-Foy, Quebec, Canada G1V 4M3 Purification of polyreactive autoantibodies and uses thereof
KR20050055717A (ko) 2002-08-26 2005-06-13 더 리전츠 오브 더 유니버시티 오브 캘리포니아 집광 다발색단을 사용하여 폴리뉴클레오티드를 검출 및 분석하기 위한 방법 및 조성물
US7563907B2 (en) 2002-12-05 2009-07-21 Dyomics Gmbh Compounds based on polymethines
ES2440920T3 (es) 2003-02-13 2014-01-31 The Regents Of The University Of California Métodos y composiciones para la detección y análisis de interacciones de proteínas que se unen a polinucleótidos utilizando multicromóforos captadores de luz
EP1650202A4 (en) 2003-07-31 2007-04-04 Taisho Pharmaceutical Co Ltd 4.5-dihydronaphtho [1,2-B] thiophene
DE10337346A1 (de) 2003-08-12 2005-03-31 Covion Organic Semiconductors Gmbh Konjugierte Polymere enthaltend Dihydrophenanthren-Einheiten und deren Verwendung
US7767785B2 (en) 2003-09-20 2010-08-03 Merck Patent Gmbh Conjugated polymers, their preparation and use thereof
US7488753B2 (en) 2003-10-09 2009-02-10 Pacific Arrow Limited Composition comprising triterpene saponins and compounds with angeloyl functional group, methods for preparing same and uses thereof
JP2005139126A (ja) 2003-11-07 2005-06-02 Konica Minolta Medical & Graphic Inc 蛍光造影剤及び体外蛍光造影方法
EP2607431B1 (en) 2003-12-05 2016-08-24 Life Technologies Corporation Cyanine dye compounds
KR20060134068A (ko) 2004-02-18 2006-12-27 토쿄고교 다이가꾸 다이할로젠화물, 고분자 화합물 및 그의 제조방법
WO2005100437A1 (ja) * 2004-04-14 2005-10-27 Kanazawa University Technology Licensing Organization Ltd. 特異な発光性を示すポリフルオレン誘導体およびその製造法
DE102004020298A1 (de) 2004-04-26 2005-11-10 Covion Organic Semiconductors Gmbh Elektrolumineszierende Polymere und deren Verwendung
DE102004020299A1 (de) 2004-04-26 2005-12-01 Covion Organic Semiconductors Gmbh Konjugierte Polymere, deren Darstellung und Verwendung
CN1594314A (zh) 2004-06-24 2005-03-16 复旦大学 基于芴的水溶性共轭聚合物及其制备方法
DK1791565T3 (en) 2004-09-23 2016-08-01 Genentech Inc Cysteingensplejsede antibodies and conjugates
EP1645610A1 (de) 2004-10-11 2006-04-12 Covion Organic Semiconductors GmbH Phenanthren-Derivate
DE112005002495B4 (de) 2004-10-11 2016-11-17 Cambridge Display Technology Ltd. Polares halbleitendes Lochtransportmaterial
US20060094859A1 (en) 2004-11-03 2006-05-04 Marrocco Matthew L Iii Class of bridged biphenylene polymers
US20060160109A1 (en) 2004-11-22 2006-07-20 Odyssey Thera, Inc. Harnessing network biology to improve drug discovery
US7897684B2 (en) 2005-01-10 2011-03-01 The Regents Of The University Of California Conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays
WO2006080406A1 (ja) 2005-01-28 2006-08-03 Taisho Pharmaceutical Co., Ltd. 三環性化合物
US7666594B2 (en) 2005-01-31 2010-02-23 The Regents Of The University Of California Methods for assaying a sample for an aggregant
US8354249B2 (en) 2005-08-11 2013-01-15 Omrix Biopharmaceuticals Ltd. Intravenous immunoglobulin composition
DE102006038683A1 (de) 2006-08-17 2008-02-21 Merck Patent Gmbh Konjugierte Polymere, deren Darstellung und Verwendung
KR20090053863A (ko) 2006-09-15 2009-05-27 지멘스 메디컬 솔루션즈 유에스에이, 인크. 인테그린에 대한 이미지화제로서 클릭 화학반응-유래된 시클로펩티드 유도체
US8158444B2 (en) 2006-10-06 2012-04-17 Sirigen, Inc. Fluorescent methods and materials for directed biomarker signal amplification
DE102007002714A1 (de) 2007-01-18 2008-07-31 Merck Patent Gmbh Neue Materialien für organische Elektrolumineszenzvorrichtungen
JP2008290963A (ja) 2007-05-24 2008-12-04 Nippon Kayaku Co Ltd 芳香族化合物の製造方法
JP2011500916A (ja) 2007-10-17 2011-01-06 エージェンシー フォー サイエンス， テクノロジー アンド リサーチ 親水性と疎水性のバランスがとれた水溶性蛍光物質
WO2009121244A1 (en) * 2008-04-03 2009-10-08 Versitech Limited Fluorophore compounds
US8114904B2 (en) * 2008-04-05 2012-02-14 Versitech Limited & Morningside Ventures Limited Luminescence quenchers and fluorogenic probes for detection of reactive species
KR20110040857A (ko) 2008-06-23 2011-04-20 바스프 에스이 신규한 중합체
DE102008049037A1 (de) 2008-09-25 2010-04-22 Merck Patent Gmbh Neue Polymere mit niedriger Polydispersität
WO2022104147A1 (en) 2020-11-13 2022-05-19 Beckman Coulter, Inc. Additives for reducing non-specific interactions between fluorescent polymer conjugates and cells in a biological sample
US20100150942A1 (en) 2008-12-03 2010-06-17 Cantor Thomas L Affinity purified human polyclonal antibodies and methods of making and using them
JP2010143895A (ja) 2008-12-22 2010-07-01 Nard Inst Ltd ピセン化合物の製造方法およびピセン化合物の結晶体
WO2010075514A1 (en) * 2008-12-23 2010-07-01 Michigan Technological University Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof
JP5388030B2 (ja) 2009-02-27 2014-01-15 国立大学法人広島大学 芳香族化合物の製造方法
US8431416B2 (en) 2009-04-01 2013-04-30 Becton, Dickinson And Company Reactive heterocycle-substituted 7-hydroxycoumarins and their conjugates
JP5438363B2 (ja) 2009-04-24 2014-03-12 ウシオケミックス株式会社 バンドギャップが広いことを特徴とする有機半導体材料
SG177355A1 (en) * 2009-06-26 2012-02-28 Sirigen Inc Signal amplified biological detection with conjugated polymers
JP2011046662A (ja) 2009-08-28 2011-03-10 Fujifilm Corp 近赤外蛍光造影剤
CN103880860B (zh) 2009-08-28 2017-05-17 帝人株式会社 新型加成化合物及其制造方法
JP5478189B2 (ja) 2009-10-16 2014-04-23 学校法人東海大学 大気安定性に優れた有機トランジスタ
US8350038B2 (en) * 2009-10-20 2013-01-08 Roche Diagnostics Operations, Inc. Fluorescence quencher molecules
CN102770465B (zh) * 2010-03-22 2015-04-22 汉高美国知识产权有限责任公司 大分子光引发剂及其可固化组合物
KR20110113297A (ko) 2010-04-09 2011-10-17 다우어드밴스드디스플레이머티리얼 유한회사 신규한 유기 전자재료용 화합물 및 이를 포함하는 유기 전계 발광 소자
CA2799540A1 (en) 2010-06-08 2011-12-15 Genentech, Inc. Cysteine engineered antibodies and conjugates
JP2011256144A (ja) 2010-06-10 2011-12-22 Yamamoto Chem Inc チオフェン化合物の製造方法
US8623324B2 (en) 2010-07-21 2014-01-07 Aat Bioquest Inc. Luminescent dyes with a water-soluble intramolecular bridge and their biological conjugates
CN102146077B (zh) 2011-01-13 2014-10-01 上海大学 芴并咪唑衍生物及其制备方法
US9971998B2 (en) 2011-02-25 2018-05-15 Paypal, Inc. Location-based automatic payment system
KR101983991B1 (ko) 2011-04-13 2019-05-30 에스에프씨 주식회사 축합아릴 화합물 및 이를 포함하는 유기전계발광소자
KR101793428B1 (ko) 2011-04-13 2017-11-03 에스에프씨 주식회사 축합아릴 화합물 및 이를 포함하는 유기전계발광소자
KR101996648B1 (ko) 2011-04-15 2019-07-04 에스에프씨 주식회사 신규한 화합물 및 이를 포함하는 유기전계발광소자
KR101923936B1 (ko) 2011-04-29 2018-11-30 에스에프씨 주식회사 신규한 화합물 및 이를 포함하는 유기전계발광소자
ES2715832T3 (es) 2011-05-27 2019-06-06 Lexicon Pharmaceuticals Inc Inhibidores a base de 4H-tieno[3,2-c]-cromeno de pectina acetilesterasa de notum y métodos de utilización de los mismos
CN102267948B (zh) 2011-06-17 2013-09-04 上海大学 芴并二咪唑衍生物及其制备方法
US8623332B2 (en) 2011-07-06 2014-01-07 Fertin Pharma A/S Chewing gum having sustained release of nicotine
US20130108619A1 (en) 2011-11-02 2013-05-02 Isaac Melamed Intravenous immunoglobulin processing, diagnostic, and treatment systems and methods
US20130177574A1 (en) 2012-01-11 2013-07-11 Paul I. Terasaki Foundation Laboratory ANTI-HLA CLASS-Ib ANTIBODIES MIMIC IMMUNOREACTIVITY AND IMMUNOMODULATORY FUNCTIONS OF INTRAVENOUS IMMUNOGLOBULIN (IVIg) USEFUL AS THERAPEUTIC IVIg MIMETICS AND METHODS OF THEIR USE
AU2013217224B2 (en) 2012-02-10 2017-04-06 Lupin Limited Antiviral compounds with a dibenzooxaheterocycle moiety
US9206271B2 (en) * 2012-03-25 2015-12-08 Wisconsin Alumni Research Foundation Fully backbone degradable and functionalizable polymers derived from the ring-opening metathesis polymerization (ROMP)
US9933341B2 (en) 2012-04-05 2018-04-03 Becton, Dickinson And Company Sample preparation for flow cytometry
WO2013183549A1 (ja) 2012-06-04 2013-12-12 住友化学株式会社 組成物及びそれを用いた電子素子
KR101488564B1 (ko) 2012-09-11 2015-02-02 주식회사 두산 유기발광 화합물 및 이를 이용한 유기 전계 발광 소자
JP6071398B2 (ja) 2012-10-05 2017-02-01 キヤノン株式会社 インデノ［１，２−ｂ］フェナンスレン化合物及びこれを有する有機発光素子
BR112015003160A2 (pt) 2012-10-24 2017-07-04 Becton Dickinson Co corantes de azaindolina - cianina substituídos por hidroxamato e bioconjugados dos mesmos
CA2900710C (en) 2013-02-08 2023-08-08 General Mills, Inc. Reduced sodium food products
US9977014B2 (en) 2013-05-10 2018-05-22 Agency For Science, Technology And Research Nanoparticle sensor for nucleic acid-protein interaction
US10240000B2 (en) 2013-09-26 2019-03-26 Polyone Corporation Aromatic polyimides suitable for 3D printing processes
JP6247560B2 (ja) 2014-02-20 2017-12-13 富士フイルム株式会社 有機薄膜トランジスタ、有機半導体薄膜および有機半導体材料
JP6140626B2 (ja) 2014-03-03 2017-05-31 富士フイルム株式会社 有機薄膜トランジスタ及びその製造方法
JP6106114B2 (ja) 2014-03-03 2017-03-29 富士フイルム株式会社 有機薄膜トランジスタ及びその製造方法
JP6110802B2 (ja) 2014-03-07 2017-04-05 富士フイルム株式会社 薄膜トランジスタ
JP6247583B2 (ja) 2014-03-28 2017-12-13 富士フイルム株式会社 有機トランジスタの有機半導体膜形成用組成物、パターン形成方法
JP6152357B2 (ja) 2014-03-28 2017-06-21 富士フイルム株式会社 有機トランジスタの有機半導体膜形成用組成物、パターン形成方法
JP2015192119A (ja) 2014-03-28 2015-11-02 富士フイルム株式会社 有機半導体膜の形成方法
JP6239457B2 (ja) 2014-07-18 2017-11-29 富士フイルム株式会社 有機半導体膜形成用組成物、及び、有機半導体素子の製造方法
WO2016009892A1 (ja) 2014-07-18 2016-01-21 富士フイルム株式会社 有機半導体膜形成用組成物、並びに、有機半導体素子及びその製造方法
JP6235143B2 (ja) 2014-07-18 2017-11-22 富士フイルム株式会社 有機半導体膜形成用組成物、及び、有機半導体素子の製造方法
EP3171420A4 (en) 2014-07-18 2017-07-05 Fujifilm Corporation Organic semiconductor film formation composition, organic semiconductor element, and production method therefor
CZ2014527A3 (cs) 2014-08-05 2016-02-17 Ústav Organické Chemie A Biochemie Akademie Věd Čr, V.V.I. Způsob detekce aktivní formy analytů ve vzorku a stanovení schopnosti dalších látek vázat se do aktivních míst těchto analytů
WO2016052056A1 (ja) 2014-09-29 2016-04-07 富士フイルム株式会社 有機半導体組成物、及び、有機半導体素子
WO2016052254A1 (ja) 2014-09-30 2016-04-07 富士フイルム株式会社 有機半導体膜形成用組成物、並びに、有機半導体素子及びその製造方法
EP3215515A1 (en) 2014-11-03 2017-09-13 Life Technologies Corporation Dibenzosilole monomers and polymers and methods for their preparation and use
CN104557723A (zh) 2014-11-05 2015-04-29 上海大学 不对称芴并咪唑衍生物及其制备方法
CN105585589B (zh) 2014-11-12 2018-10-23 中国中化股份有限公司 一种可溶性并苯化合物及其制备方法和应用
JP6318452B2 (ja) 2015-01-19 2018-05-09 富士フイルム株式会社 有機薄膜トランジスタ及びその製造方法
CN107428918B (zh) 2015-03-12 2021-07-30 贝克顿·迪金森公司 紫外线吸收聚合物染料及其使用方法
WO2016144652A1 (en) 2015-03-12 2016-09-15 Becton, Dickinson And Company Polymeric bodipy dyes and methods for using the same
JP6484700B2 (ja) 2015-03-13 2019-03-13 富士フイルム株式会社 有機半導体膜形成用組成物、有機薄膜トランジスタ、電子ペーパー、および、ディスプレイデバイス
EP3242339A4 (en) 2015-03-17 2018-01-24 Fujifilm Corporation Organic semiconductor composition and method for manufacturing organic semiconductor element
EP3319138B1 (en) 2015-06-30 2019-07-24 FUJIFILM Corporation Photoelectric conversion element, and solar battery using same
KR102502117B1 (ko) 2015-07-16 2023-02-22 에스에프씨 주식회사 염료 화합물
JP7034078B2 (ja) 2015-10-23 2022-03-11 イーアールエックス ファーマシューティカルズ インコーポレイテッド セラストロールの類似体
JP6484724B2 (ja) 2015-11-20 2019-03-13 富士フイルム株式会社 有機半導体組成物、有機半導体膜、有機薄膜トランジスタおよび有機薄膜トランジスタの製造方法
WO2017105927A1 (en) 2015-12-16 2017-06-22 Becton, Dickinson And Company Polymeric dye ratiometric sensor for analyte detection and methods of using the same
WO2017105928A1 (en) 2015-12-16 2017-06-22 Becton, Dickinson And Company Photostable fluorescent polymeric tandem dyes including luminescent metal complexes
KR102042191B1 (ko) 2016-03-23 2019-11-07 삼성에스디아이 주식회사 유기 화합물, 유기 광전자 소자 및 표시 장치
WO2017172608A1 (en) 2016-03-28 2017-10-05 Aat Bioquest, Inc. Polyfluoreno[4,5-cde]oxepine conjugates and their use in methods of analyte detection
AU2017250778B2 (en) 2016-04-15 2021-09-23 Beckman Coulter, Inc. Photoactive macromolecules and uses thereof
JP7173867B2 (ja) 2016-04-22 2022-11-16 ベクトン・ディキンソン・アンド・カンパニー 多重高分子色素デバイス及びその使用方法
CN106008138B (zh) 2016-05-23 2019-04-09 中节能万润股份有限公司 一种有机电致发光材料、应用及发光器件
CN109661439A (zh) 2016-07-07 2019-04-19 贝克顿·迪金森公司 发荧光的水溶剂化共轭聚合物
WO2018009861A1 (en) 2016-07-08 2018-01-11 Biolegend Substituted polyfluorene compounds
EP3481900A4 (en) 2016-07-11 2020-03-18 Becton, Dickinson and Company BLUE-EXCITABLE WATER-SOLUBLE POLYMERIC DYES
KR101815773B1 (ko) * 2016-07-18 2018-01-05 건국대학교 산학협력단 전하수송층을 포함하는 유기 광전변환 소자 및 이의 제조방법
KR102659149B1 (ko) 2016-09-06 2024-04-19 에스에프씨 주식회사 신규한 유기 화합물 및 이를 포함하는 유기 발광 소자
JP7097885B2 (ja) 2016-12-12 2022-07-08 ベクトン・ディキンソン・アンド・カンパニー 水溶性ポリマー色素
CN110337331B (zh) 2017-02-08 2022-04-26 贝克顿·迪金森公司 干染料试剂装置以及制造和使用所述干染料试剂装置的方法
US10870668B2 (en) 2017-05-05 2020-12-22 Universal Display Corporation Organic electroluminescent materials and devices
JP2019006739A (ja) 2017-06-28 2019-01-17 山本化成株式会社 チオフェン化合物の製造方法
EP3658648B1 (en) 2017-07-28 2021-10-27 BioLegend, Inc. Conjugated polymers and methods of use
CN107973795A (zh) 2017-11-23 2018-05-01 李现伟 一种有机电致发光材料、发光器件及显示器
CN108129496A (zh) 2017-12-01 2018-06-08 阜阳欣奕华材料科技有限公司 一种化合物、有机电致发光器件及显示装置
CN119286279A (zh) 2017-12-26 2025-01-10 贝克顿·迪金森公司 深紫外线可激发的水溶剂化聚合物染料
EP3775052B1 (en) 2018-03-30 2024-06-05 Becton, Dickinson and Company Water-soluble polymeric dyes having pendant chromophores
KR102216472B1 (ko) 2018-06-08 2021-02-17 삼성에스디아이 주식회사 유기 광전자 소자용 화합물, 유기 광전자 소자용 조성물, 유기 광전자 소자 및 표시 장치
JP2021533240A (ja) 2018-08-07 2021-12-02 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company ペンダント狭発光アクセプタを有するポリマータンデム色素
EP3636635A1 (en) 2018-10-11 2020-04-15 Academisch Ziekenhuis Leiden h.o.d.n. LUMC Imaging agents
US11992844B2 (en) 2018-11-13 2024-05-28 Becton, Dickinson And Company Dried reagent strainers and methods for making and using the same
US11584825B2 (en) 2018-12-14 2023-02-21 Beckman Coulter, Inc. Polymer dye modification and applications
US11220628B2 (en) 2019-02-20 2022-01-11 Aat Bioquest, Inc. Condensed polycyclic conjugated polymers and their use for biological detection
EP4047057A4 (en) 2019-11-19 2024-01-17 SFC Co., Ltd. EXTINGUISHER AND ITS USES
WO2021252368A1 (en) 2020-06-08 2021-12-16 Biotium, Inc. Fluorenyl cyanine dyes
US20230287170A1 (en) 2020-07-16 2023-09-14 Miltenyi Biotec B.V. & Co. KG Fluorescent dyes comprising m-conjugated 1,1 -binaphthyl-based polymers
US12169166B2 (en) 2021-02-16 2024-12-17 Aat Bioquest, Inc. Fluorogenic cyanine compounds for detecting nucleic acids
WO2022216450A1 (en) 2021-04-07 2022-10-13 Becton, Dickinson And Company Water-soluble fluorescent polymeric dyes
WO2022216449A1 (en) 2021-04-07 2022-10-13 Becton, Dickinson And Company Water-soluble yellow green absorbing dyes
AU2022269592A1 (en) 2021-05-04 2023-10-05 Beckman Coulter, Inc. Uv-absorbing polymers, compositions and uses thereof
US20240400893A1 (en) 2021-09-30 2024-12-05 Beckman Coulter, Inc. Water-soluble tetrahydropyrene based fluorescent polymers
US20230399565A1 (en) 2022-06-09 2023-12-14 Beckman Coulter, Inc. Polymer dyes and uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011091086A1 (en) * 2010-01-19 2011-07-28 Sirigen Inc. Novel reagents for directed biomarker signal amplification

Also Published As

Publication number Publication date
KR20210147091A (ko) 2021-12-06
JP7141485B2 (ja) 2022-09-22
KR20180132750A (ko) 2018-12-12
WO2017180998A2 (en) 2017-10-19
KR102693176B1 (ko) 2024-08-12
US20220213260A1 (en) 2022-07-07
AU2021212098A1 (en) 2021-08-26
EP4407013B1 (en) 2025-09-17
EP3443049B1 (en) 2021-04-14
CN109415623A (zh) 2019-03-01
KR102438354B1 (ko) 2022-08-31
JP2021165407A (ja) 2021-10-14
CN113801296B (zh) 2024-08-23
JP2019519623A (ja) 2019-07-11
JP2024120957A (ja) 2024-09-05
EP3443049A2 (en) 2019-02-20
KR102836360B1 (ko) 2025-07-23
WO2017180998A3 (en) 2017-12-28
CN113801297A (zh) 2021-12-17
JP7760000B2 (ja) 2025-10-24
US11208527B2 (en) 2021-12-28
EP3889237B1 (en) 2022-12-28
KR20230113837A (ko) 2023-08-01
EP4610656A3 (en) 2025-11-19
KR20220123561A (ko) 2022-09-07
JP7402843B2 (ja) 2023-12-21
ES3001139T3 (es) 2025-03-04
US11834551B2 (en) 2023-12-05
ES3046711T3 (en) 2025-12-02
EP3889237A1 (en) 2021-10-06
AU2017250778A1 (en) 2018-11-01
AU2021212098B2 (en) 2023-03-23
BR112018071026B1 (pt) 2023-04-11
CA3020926C (en) 2024-04-02
KR20240123421A (ko) 2024-08-13
US12312437B2 (en) 2025-05-27
BR112018071026A2 (pt) 2019-02-12
KR102331668B1 (ko) 2021-11-25
US20240052092A1 (en) 2024-02-15
CA3020926A1 (en) 2017-10-19
JP2023101725A (ja) 2023-07-21
EP4183853B1 (en) 2024-10-02
JP2025024246A (ja) 2025-02-19
EP4407013A1 (en) 2024-07-31
KR102558780B1 (ko) 2023-07-26
AU2023203991A1 (en) 2023-07-13
EP4183853A1 (en) 2023-05-24
JP6882331B2 (ja) 2021-06-02
CN109415623B (zh) 2022-07-08
ES2874129T3 (es) 2021-11-04
EP4610656A2 (en) 2025-09-03
JP2021102779A (ja) 2021-07-15
CN113801297B (zh) 2024-08-23
AU2023203991B2 (en) 2025-05-22
ES2936226T3 (es) 2023-03-15
AU2021212098B9 (en) 2023-03-30
CN113801296A (zh) 2021-12-17
US20190144601A1 (en) 2019-05-16

Similar Documents

Publication Publication Date Title
AU2021212098B2 (en) Photoactive macromolecules and uses thereof
HK40130823A (en) Photoactive macromolecules and uses thereof
HK40108461B (en) Photoactive macromolecules and uses thereof
HK40108461A (en) Photoactive macromolecules and uses thereof
HK40059981B (en) Photoactive macromolecules and uses thereof
HK40091848B (en) Photoactive macromolecules and uses thereof
HK40091848A (en) Photoactive macromolecules and uses thereof
HK40059981A (en) Photoactive macromolecules and uses thereof

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)