BR112015023489B1 - Métodos para aumentar a especificidade de edição de genoma orientado por rna em uma célula, de indução de uma ruptura em uma região alvo de uma molécula de dna de fita dupla em uma célula e de modificação de uma região alvo de uma molécula de dna de fita dupla em uma célula - Google Patents

Métodos para aumentar a especificidade de edição de genoma orientado por rna em uma célula, de indução de uma ruptura em uma região alvo de uma molécula de dna de fita dupla em uma célula e de modificação de uma região alvo de uma molécula de dna de fita dupla em uma célula Download PDF

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BR112015023489B1
BR112015023489B1 BR112015023489-5A BR112015023489A BR112015023489B1 BR 112015023489 B1 BR112015023489 B1 BR 112015023489B1 BR 112015023489 A BR112015023489 A BR 112015023489A BR 112015023489 B1 BR112015023489 B1 BR 112015023489B1
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target
seq
cell
grna
cas9
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BR112015023489-5A
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BR112015023489A2 (pt
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J. Keith Joung
Jeffry D. Sander
Yanfang Fu
Morgan Maeder
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The General Hospital Corporation
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BR112015023489-5A 2013-03-15 2014-03-14 Métodos para aumentar a especificidade de edição de genoma orientado por rna em uma célula, de indução de uma ruptura em uma região alvo de uma molécula de dna de fita dupla em uma célula e de modificação de uma região alvo de uma molécula de dna de fita dupla em uma célula BR112015023489B1 (pt)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201361799647P 2013-03-15 2013-03-15
US61/799,647 2013-03-15
US201361838148P 2013-06-21 2013-06-21
US201361838178P 2013-06-21 2013-06-21
US61/838,148 2013-06-21
US61/838,178 2013-06-21
US201361921007P 2013-12-26 2013-12-26
US61/921,007 2013-12-26
PCT/US2014/029068 WO2014144592A2 (en) 2013-03-15 2014-03-14 Using truncated guide rnas (tru-grnas) to increase specificity for rna-guided genome editing

Publications (2)

Publication Number Publication Date
BR112015023489A2 BR112015023489A2 (pt) 2017-10-10
BR112015023489B1 true BR112015023489B1 (pt) 2022-06-07

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BR112015023489-5A BR112015023489B1 (pt) 2013-03-15 2014-03-14 Métodos para aumentar a especificidade de edição de genoma orientado por rna em uma célula, de indução de uma ruptura em uma região alvo de uma molécula de dna de fita dupla em uma célula e de modificação de uma região alvo de uma molécula de dna de fita dupla em uma célula

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US (17) US10119133B2 (https=)
EP (10) EP2970986B1 (https=)
JP (11) JP6657069B2 (https=)
KR (8) KR102210322B1 (https=)
CN (6) CN112301024A (https=)
AU (10) AU2014227653B2 (https=)
BR (1) BR112015023489B1 (https=)
CA (4) CA2906553C (https=)
ES (1) ES2713503T3 (https=)
IL (2) IL289396B2 (https=)
WO (4) WO2014144761A2 (https=)
ZA (1) ZA201506814B (https=)

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