SG11201502693SA - Nmr quantification of branched chain amino acids - Google Patents

Nmr quantification of branched chain amino acids

Info

Publication number
SG11201502693SA
SG11201502693SA SG11201502693SA SG11201502693SA SG11201502693SA SG 11201502693S A SG11201502693S A SG 11201502693SA SG 11201502693S A SG11201502693S A SG 11201502693SA SG 11201502693S A SG11201502693S A SG 11201502693SA SG 11201502693S A SG11201502693S A SG 11201502693SA
Authority
SG
Singapore
Prior art keywords
amino acids
branched chain
chain amino
nmr quantification
quantification
Prior art date
Application number
SG11201502693SA
Inventor
Thomas M O'connell
Kelly A Mercier
Irina Y Shalaurova
James D Otvos
Original Assignee
Liposcience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50477859&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201502693S(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US13/801,604 external-priority patent/US9535144B2/en
Priority claimed from US13/830,199 external-priority patent/US9470771B2/en
Priority claimed from US13/830,784 external-priority patent/US9361429B2/en
Application filed by Liposcience Inc filed Critical Liposcience Inc
Publication of SG11201502693SA publication Critical patent/SG11201502693SA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46—NMR spectroscopy
    • G01R33/465—NMR spectroscopy applied to biological material, e.g. in vitro testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46—NMR spectroscopy
    • G01R33/4625—Processing of acquired signals, e.g. elimination of phase errors, baseline fitting, chemometric analysis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SG11201502693SA 2012-10-09 2013-10-09 Nmr quantification of branched chain amino acids SG11201502693SA (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201261711471P 2012-10-09 2012-10-09
US13/801,604 US9535144B2 (en) 2012-06-01 2013-03-13 NMR quantification of TMAO
US13/830,199 US9470771B2 (en) 2012-06-08 2013-03-14 NMR measurements of NMR biomarker GlycA
US13/830,784 US9361429B2 (en) 2012-06-08 2013-03-14 Multi-parameter diabetes risk evaluations
PCT/US2013/041274 WO2013180961A1 (en) 2012-06-01 2013-05-16 Nmr quantification of tmao
PCT/US2013/043343 WO2013184483A1 (en) 2012-06-08 2013-05-30 Nmr measurements of glyca
US201361831353P 2013-06-05 2013-06-05
PCT/US2013/044679 WO2013185014A1 (en) 2012-06-08 2013-06-07 Multi-parameter diabetes risk evaluations
PCT/US2013/064142 WO2014059025A1 (en) 2012-10-09 2013-10-09 Nmr quantification of branched chain amino acids

Publications (1)

Publication Number Publication Date
SG11201502693SA true SG11201502693SA (en) 2015-05-28

Family

ID=50477859

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201502693SA SG11201502693SA (en) 2012-10-09 2013-10-09 Nmr quantification of branched chain amino acids

Country Status (7)

Country Link
EP (2) EP2906956B1 (en)
JP (1) JP6268181B2 (en)
CN (1) CN104823055B (en)
AU (1) AU2013329308B2 (en)
CA (1) CA2887475C (en)
SG (1) SG11201502693SA (en)
WO (1) WO2014059025A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9470771B2 (en) 2012-06-08 2016-10-18 Liposcience, Inc. NMR measurements of NMR biomarker GlycA
US9361429B2 (en) 2012-06-08 2016-06-07 Liposcience, Inc. Multi-parameter diabetes risk evaluations
US9928345B2 (en) 2012-06-08 2018-03-27 Liposciences, Inc. Multiple-marker risk parameters predictive of conversion to diabetes
AU2014227653B2 (en) 2013-03-15 2017-04-20 The General Hospital Corporation Using RNA-guided foki nucleases (RFNs) to increase specificity for RNA-guided genome editing
JP6834488B2 (en) * 2014-10-08 2021-02-24 味の素株式会社 Acquisition method, evaluation device, evaluation program and evaluation system
US9926546B2 (en) 2015-08-28 2018-03-27 The General Hospital Corporation Engineered CRISPR-Cas9 nucleases
AU2017380103B2 (en) * 2016-12-22 2020-07-02 Numares Ag Method for determining proper functioning of an analytic system and control composition for performing said method

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0698036B2 (en) 1986-10-20 1994-12-07 小野薬品工業株式会社 Selective quantification of amino acids
US4933844A (en) 1988-09-26 1990-06-12 Otvos James D Measurement of blood lipoprotein constituents by analysis of data acquired from an NMR spectrometer
US5146166A (en) 1990-08-06 1992-09-08 Chemagnetics, Inc. Method and apparatus for enhancing sample analysis rate in magnetic resonance spectroscopy
US6617167B2 (en) 2001-08-01 2003-09-09 Liposcience, Inc. Method of determining presence and concentration of lipoprotein X in blood plasma and serum
WO2004040407A2 (en) 2002-10-25 2004-05-13 Liposcience, Inc. Methods, systems and computer programs for deconvolving the spectral contribution of chemical constituents with overlapping signals
US6768305B1 (en) 2003-09-26 2004-07-27 Varian, Inc. Temperature controlled sample changer for NMR analysis
CA2561536C (en) 2004-04-01 2017-09-19 Liposcience, Inc. Nmr clinical analyzers and related methods, systems, modules and computer program products for clinical evaluation of biosamples
JP5006524B2 (en) * 2005-05-13 2012-08-22 株式会社日立製作所 Signal processing method of NMR apparatus for specifying relaxation time
JP4358814B2 (en) * 2005-11-09 2009-11-04 花王株式会社 Sample analysis method
US7923257B2 (en) 2007-05-04 2011-04-12 Perkinelmer Health Sciences, Inc. Detecting isomers using differential derivatization mass spectrometry
EP2019311A1 (en) * 2007-07-23 2009-01-28 F.Hoffmann-La Roche Ag A method for detecting a target substance by nuclear magnetic resonance
WO2009064843A1 (en) 2007-11-13 2009-05-22 Bayer Healthcare Llc Method to measure amino acid concentrations
WO2010002479A1 (en) 2008-07-03 2010-01-07 Lowery Thomas Jay Jr Magnetic nanosensor compositions and bioanalytical assays therefor
ES2799327T3 (en) * 2009-05-05 2020-12-16 Infandx Ag Method to diagnose suffocation
EP3100610A1 (en) 2009-07-24 2016-12-07 Baylor College Of Medicine Methods of modulation of branched chain acids and uses thereof
EP2572193B1 (en) * 2010-05-21 2017-11-01 The Governors Of The University Of Alberta Methods for the assessment of colorectal cancer and colorectal polyps by measurement of metabolites in urine

Also Published As

Publication number Publication date
AU2013329308A1 (en) 2015-04-30
JP2015537197A (en) 2015-12-24
CA2887475C (en) 2021-12-14
EP3842818A1 (en) 2021-06-30
JP6268181B2 (en) 2018-01-24
WO2014059025A1 (en) 2014-04-17
AU2013329308B2 (en) 2018-11-01
EP2906956A4 (en) 2016-06-29
EP2906956A1 (en) 2015-08-19
CN104823055A (en) 2015-08-05
CN104823055B (en) 2017-12-05
CA2887475A1 (en) 2014-04-17
EP2906956B1 (en) 2020-11-25

Similar Documents

Publication Publication Date Title
HK1211569A1 (en) Amino acid derivatives
HK1207156A1 (en) Nmr measurements of glyca glyca
HK1210172A1 (en) Crystal of dispiropyrrolidine derivative
DK2890402T3 (en) MODIFIED AMINO ACIDS INCLUDING AN AZIDOG GROUP
HK1210144A1 (en) New indanyloxydihydrobenzofuranylacetic acids
EP2788507A4 (en) Method of measuring immune activation
IL234914A (en) Quantification of impurities for release testing of peptide products
ZA201407034B (en) Phenyl alkanoic acid derivatives as gpr agonists
PL2563850T3 (en) Expansible beads of polyamide
EP2750681A4 (en) Branched discrette peg constructs
SG11201502693SA (en) Nmr quantification of branched chain amino acids
EP2813487A4 (en) Basic amino acid derivative
EP2804488A4 (en) Method of instantizing amino acids
EP2861655A4 (en) Methods for desolventization of bagasse
IL235556B (en) Enzymatic synthesis of l-nucleic acids
EP2726849A4 (en) Measurement of critical dimension
BR112013033734A2 (en) branched polyamide with different blocks
GB201208293D0 (en) Hydrochlorice salt of peptide
BR112013033512A2 (en) branched polyamide
EP2859338A4 (en) Nmr quantification of tmao
EP2726652A4 (en) Method of protein display
EP2681188A4 (en) Amidation process
HK1200458A1 (en) Methods of isolating 4-chloro-2-fluoro-3-substituted-phenylboronic acids 4--2--3--
EP2909226A4 (en) Derivatives of collagen-binding hairpin peptides
EP3560952C0 (en) Variant of bpifb4 protein