US20190098879A1 - Non-Human Animals Comprising A Humanized TTR Locus And Methods Of Use - Google Patents

Non-Human Animals Comprising A Humanized TTR Locus And Methods Of Use Download PDF

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Publication number
US20190098879A1
US20190098879A1 US16/145,859 US201816145859A US2019098879A1 US 20190098879 A1 US20190098879 A1 US 20190098879A1 US 201816145859 A US201816145859 A US 201816145859A US 2019098879 A1 US2019098879 A1 US 2019098879A1
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United States
Prior art keywords
ttr
human
sequence
non
locus
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Pending
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US16/145,859
Inventor
Meghan Drummond-Samuelson
Jeffery Haines
Suzanne Hartford
David Frendewey
Brian Zambrowicz
Andrew J. Murphy
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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Publication date
Priority to US201762565980P priority Critical
Priority to US201862679142P priority
Priority to US201862720292P priority
Application filed by Regeneron Pharmaceuticals Inc filed Critical Regeneron Pharmaceuticals Inc
Priority to US16/145,859 priority patent/US20190098879A1/en
Assigned to REGENERON PHARMACEUTICALS, INC. reassignment REGENERON PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: FRENDEWEY, DAVID, HAINES, Jeffery, HARTFORD, Suzanne, MURPHY, ANDREW J., DRUMMOND-SAMUELSON, Meghan, ZAMBROWICZ, BRIAN
Publication of US20190098879A1 publication Critical patent/US20190098879A1/en
Application status is Pending legal-status Critical

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