MX2019003674A - Enzimas modificadoras de ácido nucleico guiadas por arn y métodos de uso de estas. - Google Patents

Enzimas modificadoras de ácido nucleico guiadas por arn y métodos de uso de estas.

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Publication number
MX2019003674A
MX2019003674A MX2019003674A MX2019003674A MX2019003674A MX 2019003674 A MX2019003674 A MX 2019003674A MX 2019003674 A MX2019003674 A MX 2019003674A MX 2019003674 A MX2019003674 A MX 2019003674A MX 2019003674 A MX2019003674 A MX 2019003674A
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Mexico
Prior art keywords
casx
nucleic acids
acids encoding
guide rnas
proteins
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MX2019003674A
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English (en)
Inventor
Jennifer A Doudna
Jillian F Banfield
David Burstein
Lucas Benjamin Harrington
Steven C Strutt
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Univ California
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Publication of MX2019003674A publication Critical patent/MX2019003674A/es

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Abstract

La presente descripción proporciona proteínas CasX, ácidos nucleicos que codifican las proteínas CasX y células hospedadoras modificadas que comprenden las proteínas CasX y/o ácidos nucleicos que las codifican. Las proteínas CasX son útiles en una variedad de aplicaciones que se proporcionan. La presente descripción proporciona ARN guías de CasX que se unen a y proporcionan especificidad de secuencia a las proteínas CasX, ácidos nucleicos que codifican los ARN guías de CasX y células hospedadoras modificadas que comprenden los ARN guías de CasX y/o ácidos nucleicos que los codifican. Los ARN guías de CasX son útiles en una variedad de aplicaciones que se proporcionan. La presente descripción proporciona polipéptidos Cas9 arqueanos y ácidos nucleicos que los codifican, así como sus ARN guías de Cas9 arqueanos asociados y ácidos nucleicos que los codifican.
MX2019003674A 2016-09-30 2017-09-28 Enzimas modificadoras de ácido nucleico guiadas por arn y métodos de uso de estas. MX2019003674A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662402846P 2016-09-30 2016-09-30
PCT/US2017/054081 WO2018064371A1 (en) 2016-09-30 2017-09-28 Rna-guided nucleic acid modifying enzymes and methods of use thereof

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MX2019003674A true MX2019003674A (es) 2021-01-08

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MX2019003674A MX2019003674A (es) 2016-09-30 2017-09-28 Enzimas modificadoras de ácido nucleico guiadas por arn y métodos de uso de estas.

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US (3) US11873504B2 (es)
EP (1) EP3523426A4 (es)
JP (2) JP2019532644A (es)
KR (2) KR20190071725A (es)
CN (1) CN110023494A (es)
AU (1) AU2017335890A1 (es)
BR (1) BR112019006384A2 (es)
CA (1) CA3038960A1 (es)
EA (1) EA201990861A1 (es)
GB (1) GB2569733B (es)
IL (1) IL265598A (es)
MX (1) MX2019003674A (es)
WO (1) WO2018064371A1 (es)

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