AR035668A1 - Imidazoquinolinas y 6,7,8,9-tetrahidroimidazoquinolinas, composiciones farmaceuticas que las comprenden, uso de dichos compuestos en la preparacion de medicamentos, e intermediarios utiles en la sintesis de dichos compuestos - Google Patents
Imidazoquinolinas y 6,7,8,9-tetrahidroimidazoquinolinas, composiciones farmaceuticas que las comprenden, uso de dichos compuestos en la preparacion de medicamentos, e intermediarios utiles en la sintesis de dichos compuestosInfo
- Publication number
- AR035668A1 AR035668A1 ARP010105730A ARP010105730A AR035668A1 AR 035668 A1 AR035668 A1 AR 035668A1 AR P010105730 A ARP010105730 A AR P010105730A AR P010105730 A ARP010105730 A AR P010105730A AR 035668 A1 AR035668 A1 AR 035668A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- alkenyl
- compounds
- aryl
- heteroaryl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 230000015572 biosynthetic process Effects 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 4
- 125000003342 alkenyl group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000000027 (C1-C10) alkoxy group Chemical group 0.000 abstract 1
- RHKWIGHJGOEUSM-UHFFFAOYSA-N 3h-imidazo[4,5-h]quinoline Chemical class C1=CN=C2C(N=CN3)=C3C=CC2=C1 RHKWIGHJGOEUSM-UHFFFAOYSA-N 0.000 abstract 1
- JDQVYSWJFCKKPX-UHFFFAOYSA-N 6,7,8,9-tetrahydro-3h-imidazo[4,5-h]quinoline Chemical class C1CCNC2=C1C=CC1=C2N=CN1 JDQVYSWJFCKKPX-UHFFFAOYSA-N 0.000 abstract 1
- 125000006374 C2-C10 alkenyl group Chemical group 0.000 abstract 1
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000003607 modifier Substances 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- AIDS & HIV (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Transplantation (AREA)
- Psychiatry (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25421800P | 2000-12-08 | 2000-12-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR035668A1 true AR035668A1 (es) | 2004-06-23 |
Family
ID=22963391
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010105730A AR035668A1 (es) | 2000-12-08 | 2001-12-10 | Imidazoquinolinas y 6,7,8,9-tetrahidroimidazoquinolinas, composiciones farmaceuticas que las comprenden, uso de dichos compuestos en la preparacion de medicamentos, e intermediarios utiles en la sintesis de dichos compuestos |
| ARP010105729A AR035667A1 (es) | 2000-12-08 | 2001-12-10 | Imidazo[4,5-c]quinolin-4-aminas y tetrahidroimidazo[4,5-c]quinolin-4-aminas, composiciones farmaceuticas que las comprenden, uso de dichos compuestos en la preparacion de medicamentos, e intermediarios utiles en la sintesis de dichos compuestos |
| ARP010105728A AR035666A1 (es) | 2000-12-08 | 2001-12-10 | Imidazo[4,5-c]quinolin-4-aminas y tetrahidroimidazo[4,5-c]quinolin-4-aminas, composiciones farmaceuticas que las comprenden, uso de dichos compuestos en la preparacion de medicamentos, e intermediarios utiles en la sintesis de dichos compuestos |
| ARP010105726A AR035664A1 (es) | 2000-12-08 | 2001-12-10 | Imidazo[4,5-c]quinolin-4-aminas y tetrahidroimidazo[4,5-c]quinolin-4-aminas, composiciones farmaceuticas que las comprenden, uso de dichos compuestos en la preparacion de medicamentos, e intermediarios utiles en la sintesis de dichos compuestos |
| ARP010105727A AR035665A1 (es) | 2000-12-08 | 2001-12-10 | Imidazoquinolinas y 6,7,8,9-tetrahidroimidazoquinolinas, composiciones farmaceuticas que las comprenden, uso de dichos compuestos en la preparacion de medicamentos, e intermediarios utiles en la sintesis de dichos compuestos |
| ARP010105731A AR035669A1 (es) | 2000-12-08 | 2001-12-10 | Imidazoquinolinas y 6,7,8,9-tetrahidroimidazoquinolinas, composiciones que las comprenden, y usos de dichos compuestos en la preparacion de medicamentos |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010105729A AR035667A1 (es) | 2000-12-08 | 2001-12-10 | Imidazo[4,5-c]quinolin-4-aminas y tetrahidroimidazo[4,5-c]quinolin-4-aminas, composiciones farmaceuticas que las comprenden, uso de dichos compuestos en la preparacion de medicamentos, e intermediarios utiles en la sintesis de dichos compuestos |
| ARP010105728A AR035666A1 (es) | 2000-12-08 | 2001-12-10 | Imidazo[4,5-c]quinolin-4-aminas y tetrahidroimidazo[4,5-c]quinolin-4-aminas, composiciones farmaceuticas que las comprenden, uso de dichos compuestos en la preparacion de medicamentos, e intermediarios utiles en la sintesis de dichos compuestos |
| ARP010105726A AR035664A1 (es) | 2000-12-08 | 2001-12-10 | Imidazo[4,5-c]quinolin-4-aminas y tetrahidroimidazo[4,5-c]quinolin-4-aminas, composiciones farmaceuticas que las comprenden, uso de dichos compuestos en la preparacion de medicamentos, e intermediarios utiles en la sintesis de dichos compuestos |
| ARP010105727A AR035665A1 (es) | 2000-12-08 | 2001-12-10 | Imidazoquinolinas y 6,7,8,9-tetrahidroimidazoquinolinas, composiciones farmaceuticas que las comprenden, uso de dichos compuestos en la preparacion de medicamentos, e intermediarios utiles en la sintesis de dichos compuestos |
| ARP010105731A AR035669A1 (es) | 2000-12-08 | 2001-12-10 | Imidazoquinolinas y 6,7,8,9-tetrahidroimidazoquinolinas, composiciones que las comprenden, y usos de dichos compuestos en la preparacion de medicamentos |
Country Status (31)
| Country | Link |
|---|---|
| US (8) | US6683088B2 (enExample) |
| EP (6) | EP1339715A2 (enExample) |
| JP (7) | JP2004515501A (enExample) |
| KR (6) | KR20040028691A (enExample) |
| CN (6) | CN1297554C (enExample) |
| AR (6) | AR035668A1 (enExample) |
| AT (3) | ATE319711T1 (enExample) |
| AU (12) | AU2002239517B2 (enExample) |
| BR (6) | BR0116032A (enExample) |
| CA (6) | CA2431151A1 (enExample) |
| CY (2) | CY1105586T1 (enExample) |
| CZ (6) | CZ20031562A3 (enExample) |
| DE (3) | DE60111076T2 (enExample) |
| DK (3) | DK1341791T3 (enExample) |
| EE (6) | EE200300272A (enExample) |
| ES (3) | ES2242782T3 (enExample) |
| HR (6) | HRP20030467B1 (enExample) |
| HU (6) | HUP0400704A2 (enExample) |
| IL (6) | IL155884A0 (enExample) |
| MX (6) | MXPA03004975A (enExample) |
| NO (6) | NO20032452L (enExample) |
| NZ (6) | NZ526087A (enExample) |
| PL (7) | PL365907A1 (enExample) |
| PT (2) | PT1341790E (enExample) |
| RU (6) | RU2302418C2 (enExample) |
| SI (1) | SI1341790T1 (enExample) |
| SK (6) | SK287732B6 (enExample) |
| TW (3) | TW584633B (enExample) |
| UA (2) | UA74852C2 (enExample) |
| WO (6) | WO2002046193A2 (enExample) |
| ZA (6) | ZA200305272B (enExample) |
Families Citing this family (209)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5741908A (en) | 1996-06-21 | 1998-04-21 | Minnesota Mining And Manufacturing Company | Process for reparing imidazoquinolinamines |
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| JP2006523452A (ja) | 2003-03-25 | 2006-10-19 | スリーエム イノベイティブ プロパティズ カンパニー | 共通のＴｏｌｌ様受容体を通じて媒介される細胞活性の選択的活性化 |
| AU2004229478B2 (en) | 2003-04-10 | 2009-12-24 | 3M Innovative Properties Company | Delivery of immune response modifier compounds |
| GEP20084545B (en) | 2003-09-05 | 2008-11-25 | Anadys Pharmaceuticals Inc | Introducing tlr7 ligands and prodrugs thereof for the treatment of hepatitis c viral infection |
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2001
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- 2001-12-06 KR KR10-2003-7007532A patent/KR20040023576A/ko not_active Withdrawn
- 2001-12-06 EP EP01992018A patent/EP1343784B1/en not_active Expired - Lifetime
- 2001-12-06 HU HU0700062A patent/HUP0700062A2/hu active IP Right Revival
- 2001-12-06 EP EP01987297A patent/EP1341791B1/en not_active Expired - Lifetime
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- 2001-12-06 RU RU2003116123/04A patent/RU2003116123A/ru not_active Application Discontinuation
- 2001-12-06 KR KR10-2003-7007539A patent/KR20040047733A/ko not_active Withdrawn
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- 2001-12-06 CZ CZ20031592A patent/CZ303462B6/cs not_active IP Right Cessation
- 2001-12-06 KR KR10-2003-7007537A patent/KR20030070050A/ko not_active Withdrawn
- 2001-12-06 HU HU0600338A patent/HUP0600338A2/hu active IP Right Revival
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2003
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- 2003-05-28 NO NO20032449A patent/NO20032449L/no not_active Application Discontinuation
- 2003-05-30 NO NO20032473A patent/NO326159B1/no not_active IP Right Cessation
- 2003-06-06 NO NO20032595A patent/NO20032595D0/no not_active Application Discontinuation
- 2003-06-06 NO NO20032596A patent/NO20032596D0/no not_active Application Discontinuation
- 2003-07-08 ZA ZA2003/05272A patent/ZA200305272B/en unknown
- 2003-07-08 ZA ZA200305273A patent/ZA200305273B/en unknown
- 2003-07-08 ZA ZA200305274A patent/ZA200305274B/en unknown
- 2003-07-08 ZA ZA200305270A patent/ZA200305270B/en unknown
- 2003-07-08 ZA ZA200305271A patent/ZA200305271B/en unknown
- 2003-07-08 ZA ZA200305275A patent/ZA200305275B/en unknown
- 2003-10-07 US US10/680,989 patent/US7049439B2/en not_active Expired - Fee Related
- 2003-10-29 US US10/696,476 patent/US20040092545A1/en not_active Abandoned
- 2003-10-29 US US10/696,753 patent/US6953804B2/en not_active Expired - Fee Related
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2005
- 2005-02-28 US US11/069,033 patent/US7132429B2/en not_active Expired - Fee Related
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- 2005-08-24 CY CY20051101024T patent/CY1105586T1/el unknown
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2007
- 2007-05-09 CY CY20071100621T patent/CY1106569T1/el unknown
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2009
- 2009-11-06 JP JP2009255040A patent/JP2010031040A/ja not_active Ceased
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