DE60117859T2 - HARNSTOFFSUBSTITUIERTE IMIDAZOCHINOLINETHER und Arzneimittel, die diese umfassen. - Google Patents
HARNSTOFFSUBSTITUIERTE IMIDAZOCHINOLINETHER und Arzneimittel, die diese umfassen. Download PDFInfo
- Publication number
- DE60117859T2 DE60117859T2 DE60117859T DE60117859T DE60117859T2 DE 60117859 T2 DE60117859 T2 DE 60117859T2 DE 60117859 T DE60117859 T DE 60117859T DE 60117859 T DE60117859 T DE 60117859T DE 60117859 T2 DE60117859 T2 DE 60117859T2
- Authority
- DE
- Germany
- Prior art keywords
- alkyl
- alkylene
- aryl
- heteroaryl
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 CC(C=C1)(C=Cc2c1c(*(*O*)C=*1)c1c*2O)P Chemical compound CC(C=C1)(C=Cc2c1c(*(*O*)C=*1)c1c*2O)P 0.000 description 3
- DNPSVDYUHTZCQF-UHFFFAOYSA-N CNc1c2nc(CCOC)[n](CCOCCNC(N3CCOCC3)=O)c2c(cccc2)c2n1 Chemical compound CNc1c2nc(CCOC)[n](CCOCCNC(N3CCOCC3)=O)c2c(cccc2)c2n1 DNPSVDYUHTZCQF-UHFFFAOYSA-N 0.000 description 1
- ZLZKHTRPQRBTHF-UHFFFAOYSA-N COCCc1nc2c(N)nc(cccc3)c3c2[n]1CCOCCNC(Nc1ccccc1)=O Chemical compound COCCc1nc2c(N)nc(cccc3)c3c2[n]1CCOCCNC(Nc1ccccc1)=O ZLZKHTRPQRBTHF-UHFFFAOYSA-N 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
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- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A61P31/20—Antivirals for DNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P33/00—Antiparasitic agents
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- A—HUMAN NECESSITIES
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- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
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- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- AIDS & HIV (AREA)
- Ophthalmology & Optometry (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25421800P | 2000-12-08 | 2000-12-08 | |
| US254218P | 2000-12-08 | ||
| PCT/US2001/046696 WO2002046191A2 (en) | 2000-12-08 | 2001-12-06 | Urea substituted imidazoquinoline ethers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60117859D1 DE60117859D1 (de) | 2006-05-04 |
| DE60117859T2 true DE60117859T2 (de) | 2006-11-23 |
Family
ID=22963391
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60117859T Expired - Fee Related DE60117859T2 (de) | 2000-12-08 | 2001-12-06 | HARNSTOFFSUBSTITUIERTE IMIDAZOCHINOLINETHER und Arzneimittel, die diese umfassen. |
| DE60111076T Expired - Lifetime DE60111076T2 (de) | 2000-12-08 | 2001-12-06 | Thioethersubstituierte imidazochinoline |
| DE60126645T Expired - Fee Related DE60126645T2 (de) | 2000-12-08 | 2001-12-06 | Sulfonamidether - substituierte imidazochinoline |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60111076T Expired - Lifetime DE60111076T2 (de) | 2000-12-08 | 2001-12-06 | Thioethersubstituierte imidazochinoline |
| DE60126645T Expired - Fee Related DE60126645T2 (de) | 2000-12-08 | 2001-12-06 | Sulfonamidether - substituierte imidazochinoline |
Country Status (31)
| Country | Link |
|---|---|
| US (8) | US6656938B2 (enExample) |
| EP (6) | EP1341791B1 (enExample) |
| JP (7) | JP2004529078A (enExample) |
| KR (6) | KR20030070050A (enExample) |
| CN (6) | CN1252070C (enExample) |
| AR (6) | AR035669A1 (enExample) |
| AT (3) | ATE353895T1 (enExample) |
| AU (12) | AU3249702A (enExample) |
| BR (6) | BR0116047A (enExample) |
| CA (6) | CA2436984A1 (enExample) |
| CY (2) | CY1105586T1 (enExample) |
| CZ (6) | CZ20031562A3 (enExample) |
| DE (3) | DE60117859T2 (enExample) |
| DK (3) | DK1343784T3 (enExample) |
| EE (6) | EE200300275A (enExample) |
| ES (3) | ES2260323T3 (enExample) |
| HR (6) | HRP20030462A2 (enExample) |
| HU (6) | HUP0700062A2 (enExample) |
| IL (6) | IL155903A0 (enExample) |
| MX (6) | MXPA03004973A (enExample) |
| NO (6) | NO20032449L (enExample) |
| NZ (6) | NZ526086A (enExample) |
| PL (7) | PL365995A1 (enExample) |
| PT (2) | PT1341791E (enExample) |
| RU (6) | RU2308456C2 (enExample) |
| SI (1) | SI1341790T1 (enExample) |
| SK (6) | SK6842003A3 (enExample) |
| TW (3) | TWI222972B (enExample) |
| UA (2) | UA74852C2 (enExample) |
| WO (6) | WO2002046193A2 (enExample) |
| ZA (6) | ZA200305275B (enExample) |
Families Citing this family (209)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5741908A (en) | 1996-06-21 | 1998-04-21 | Minnesota Mining And Manufacturing Company | Process for reparing imidazoquinolinamines |
| UA67760C2 (uk) * | 1997-12-11 | 2004-07-15 | Міннесота Майнінг Енд Мануфакчурінг Компані | Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки |
| US6541485B1 (en) | 1999-06-10 | 2003-04-01 | 3M Innovative Properties Company | Urea substituted imidazoquinolines |
| US6331539B1 (en) * | 1999-06-10 | 2001-12-18 | 3M Innovative Properties Company | Sulfonamide and sulfamide substituted imidazoquinolines |
| US6573273B1 (en) | 1999-06-10 | 2003-06-03 | 3M Innovative Properties Company | Urea substituted imidazoquinolines |
| US6756382B2 (en) | 1999-06-10 | 2004-06-29 | 3M Innovative Properties Company | Amide substituted imidazoquinolines |
| US6916925B1 (en) | 1999-11-05 | 2005-07-12 | 3M Innovative Properties Co. | Dye labeled imidazoquinoline compounds |
| JP3436512B2 (ja) * | 1999-12-28 | 2003-08-11 | 株式会社デンソー | アクセル装置 |
| US6677347B2 (en) * | 2000-12-08 | 2004-01-13 | 3M Innovative Properties Company | Sulfonamido ether substituted imidazoquinolines |
| US6667312B2 (en) * | 2000-12-08 | 2003-12-23 | 3M Innovative Properties Company | Thioether substituted imidazoquinolines |
| US6525064B1 (en) | 2000-12-08 | 2003-02-25 | 3M Innovative Properties Company | Sulfonamido substituted imidazopyridines |
| US6545016B1 (en) * | 2000-12-08 | 2003-04-08 | 3M Innovative Properties Company | Amide substituted imidazopyridines |
| US6664264B2 (en) * | 2000-12-08 | 2003-12-16 | 3M Innovative Properties Company | Thioether substituted imidazoquinolines |
| US6677348B2 (en) | 2000-12-08 | 2004-01-13 | 3M Innovative Properties Company | Aryl ether substituted imidazoquinolines |
| UA74852C2 (en) * | 2000-12-08 | 2006-02-15 | 3M Innovative Properties Co | Urea-substituted imidazoquinoline ethers |
| US6545017B1 (en) | 2000-12-08 | 2003-04-08 | 3M Innovative Properties Company | Urea substituted imidazopyridines |
| US6660735B2 (en) * | 2000-12-08 | 2003-12-09 | 3M Innovative Properties Company | Urea substituted imidazoquinoline ethers |
| US6664265B2 (en) | 2000-12-08 | 2003-12-16 | 3M Innovative Properties Company | Amido ether substituted imidazoquinolines |
| US6660747B2 (en) * | 2000-12-08 | 2003-12-09 | 3M Innovative Properties Company | Amido ether substituted imidazoquinolines |
| US7226928B2 (en) * | 2001-06-15 | 2007-06-05 | 3M Innovative Properties Company | Methods for the treatment of periodontal disease |
| US20030199538A1 (en) * | 2001-11-29 | 2003-10-23 | 3M Innovative Properties Company | Pharmaceutical formulation comprising an immune response modifier |
| CA2365732A1 (en) | 2001-12-20 | 2003-06-20 | Ibm Canada Limited-Ibm Canada Limitee | Testing measurements |
| US6677349B1 (en) * | 2001-12-21 | 2004-01-13 | 3M Innovative Properties Company | Sulfonamide and sulfamide substituted imidazoquinolines |
| IL147953A (en) | 2002-02-01 | 2008-04-13 | Meir Bialer | Derivatives and pharmaceutical compositions of n-hydroxymethyl tetramethylcyclopropyl- |
| HUE025145T2 (en) | 2002-02-22 | 2016-01-28 | Meda Ab | A method for reducing and treating immunosuppression induced by ultraviolet B radiation |
| GB0211649D0 (en) * | 2002-05-21 | 2002-07-03 | Novartis Ag | Organic compounds |
| EP1513524A4 (en) | 2002-06-07 | 2008-09-03 | 3M Innovative Properties Co | WITH ETHER SUBSTITUTED IMIDAZOPYRIDINE |
| JP4903997B2 (ja) * | 2002-07-02 | 2012-03-28 | サザン リサーチ インスティチュート | ＦｔｓＺの阻害剤およびそれらの用途 |
| DK1545597T3 (da) * | 2002-08-15 | 2011-01-31 | 3M Innovative Properties Co | Immunstimulerende sammensætninger og fremgangsmåde til stimulering af en immunrespons |
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- 2001-12-07 TW TW090130402A patent/TWI222972B/zh active
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2003
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2005
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2007
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2009
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