AR024384A1 - UNA FORMA DE DOSIFICACIoN FARMACÉUTICA DE DISOLUCIoN INSTANTÁNEA Y UN MÉTODO PARA PREPARARLA - Google Patents

UNA FORMA DE DOSIFICACIoN FARMACÉUTICA DE DISOLUCIoN INSTANTÁNEA Y UN MÉTODO PARA PREPARARLA

Info

Publication number
AR024384A1
AR024384A1 ARP000103004A ARP000103004A AR024384A1 AR 024384 A1 AR024384 A1 AR 024384A1 AR P000103004 A ARP000103004 A AR P000103004A AR P000103004 A ARP000103004 A AR P000103004A AR 024384 A1 AR024384 A1 AR 024384A1
Authority
AR
Argentina
Prior art keywords
granules
prepare
dosage form
pharmaceutical dosage
dosage forms
Prior art date
Application number
ARP000103004A
Other languages
English (en)
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24186805&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR024384(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of AR024384A1 publication Critical patent/AR024384A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se proporcionan gránulos para la produccion de formas de dosificacion oral, farmacéuticas de disolucion instantánea. Además de uno o más medicamentos, losgránulos se componen de una combinacion de excipientes que consiste en un superdesintegrante,un agene de dispersion, un agente de distribucion, y unaglutinante y también pueden incluir otros ingredientes convencionales tales como agentes dulcificantes y saborizantes. Los gránulos objetivo son ventajosos enque éstos son estables y se puedenpre parar sin la ayuda de solventes y sin la necesidad de ambientes o manejo especiales. Las formas de dosificacion.especialmente tabletas, preparadas de los mismos en un equipo convencional se desintegran en la boca abajo de aproximadamenteveinticinco segundos.
ARP000103004A 2000-04-12 2000-06-16 UNA FORMA DE DOSIFICACIoN FARMACÉUTICA DE DISOLUCIoN INSTANTÁNEA Y UN MÉTODO PARA PREPARARLA AR024384A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54794800A 2000-04-12 2000-04-12

Publications (1)

Publication Number Publication Date
AR024384A1 true AR024384A1 (es) 2002-10-02

Family

ID=24186805

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000103004A AR024384A1 (es) 2000-04-12 2000-06-16 UNA FORMA DE DOSIFICACIoN FARMACÉUTICA DE DISOLUCIoN INSTANTÁNEA Y UN MÉTODO PARA PREPARARLA

Country Status (43)

Country Link
US (3) US20100016448A1 (es)
EP (2) EP1566174A3 (es)
JP (1) JP3773763B2 (es)
KR (1) KR100477293B1 (es)
CN (1) CN100353933C (es)
AR (1) AR024384A1 (es)
AT (1) ATE328584T1 (es)
AU (1) AU752214B2 (es)
BG (1) BG65007B1 (es)
BR (1) BR0003158A (es)
CA (1) CA2311734C (es)
CO (1) CO5190672A1 (es)
CY (1) CY1105170T1 (es)
CZ (1) CZ299145B6 (es)
DE (1) DE60028536T2 (es)
DK (1) DK1145711T3 (es)
EE (1) EE04331B1 (es)
EG (1) EG23943A (es)
ES (1) ES2265836T3 (es)
GE (1) GEP20022851B (es)
HK (1) HK1039572B (es)
HU (1) HU228864B1 (es)
ID (1) ID29837A (es)
IL (1) IL136901A (es)
IN (1) IN188856B (es)
LT (1) LT4896B (es)
LV (1) LV12731B (es)
MY (1) MY125766A (es)
NO (1) NO330270B1 (es)
NZ (1) NZ505302A (es)
PE (1) PE20010298A1 (es)
PL (1) PL200409B1 (es)
PT (1) PT1145711E (es)
RO (1) RO118563B1 (es)
RU (1) RU2201216C2 (es)
SG (2) SG108230A1 (es)
SI (1) SI20511B (es)
SK (1) SK286368B6 (es)
TR (1) TR200001810A2 (es)
TW (1) TWI262799B (es)
UA (1) UA63993C2 (es)
UY (1) UY26306A1 (es)
ZA (1) ZA200003121B (es)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2311734C (en) 2000-04-12 2011-03-08 Bristol-Myers Squibb Company Flash-melt oral dosage formulation
US20020076437A1 (en) 2000-04-12 2002-06-20 Sanjeev Kothari Flashmelt oral dosage formulation
US7053092B2 (en) 2001-01-29 2006-05-30 Otsuka Pharmaceutical Co., Ltd. 5-HT1a receptor subtype agonist
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
MY129350A (en) * 2001-04-25 2007-03-30 Bristol Myers Squibb Co Aripiprazole oral solution
PE20030445A1 (es) * 2001-09-25 2003-07-26 Otsuka Pharma Co Ltd Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
AR033485A1 (es) 2001-09-25 2003-12-26 Otsuka Pharma Co Ltd Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
GB0123400D0 (en) * 2001-09-28 2001-11-21 Novartis Ag Organic compounds
BR0117147A (pt) * 2001-10-09 2006-05-09 Bristol Myers Squibb Co preparado de dosagem oral de desintegração instantánea
US6610266B2 (en) * 2001-11-28 2003-08-26 Michael C. Withiam Calcium metasilicates and methods for making
EP1453826A1 (en) * 2001-12-10 2004-09-08 Dr. Reddy's Laboratories Ltd. Amorphous form of 2-n-butyl-3-[[2-(1h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4'] non-1-en-4-one
AU2003221326A1 (en) * 2002-03-06 2003-09-16 Kyowa Hakko Kogyo Co., Ltd. Tablets quickly disintegrating in oral cavity
AU2003238670A1 (en) * 2002-04-05 2003-10-27 Cadila Healthcare Limited Fast disintegrating oral dosage forms
TWI275392B (en) * 2002-04-08 2007-03-11 Bristol Myers Squibb Co Low dose liquid entecavir formulations and use
RU2342931C2 (ru) 2002-08-20 2009-01-10 Бристол-Маерс Сквибб Компани Состав на основе комплекса арипипразола
IN2012DN00604A (es) * 2002-12-11 2015-08-21 Bristol Myers Squibb Co
JP3841804B2 (ja) 2003-10-15 2006-11-08 富士化学工業株式会社 口腔内速崩壊性錠剤用の組成物
US8349361B2 (en) 2003-10-15 2013-01-08 Fuji Chemical Industry Co., Ltd. Composition for rapid disintegrating tablet in oral cavity
DE602005025755D1 (de) 2004-06-04 2011-02-17 Teva Pharma Irbesartan enthaltende pharmazeutische zusammensetzung
JP3996626B2 (ja) * 2004-06-22 2007-10-24 塩野義製薬株式会社 口腔内速崩壊錠
CA2600533A1 (en) * 2005-03-24 2006-09-28 Daiichi Sankyo Company, Limited Pharmaceutical composition
WO2007081366A1 (en) 2006-01-05 2007-07-19 Teva Pharmaceutical Industries Ltd. Wet granulation pharmaceutical compositions of aripiprazole
PL1808165T3 (pl) * 2006-01-05 2009-09-30 Teva Pharma Suche formulacje aripiprazolu
DE602006013261D1 (de) * 2006-01-09 2010-05-12 Krka D D Irbesartan enthaltende feste Zubereitung
KR101324898B1 (ko) 2006-03-31 2013-11-04 루비콘 리서치 피브이티. 엘티디. 구강 붕해 정제
PL2487161T3 (pl) 2007-02-23 2017-03-31 Gilead Sciences, Inc. Modulatory farmakokinetycznych właściwości środków terapeutycznych
WO2008125388A1 (en) * 2007-04-17 2008-10-23 Ratiopharm Gmbh Pharmaceutical compositions comprising irbesartan
CA2686035C (en) * 2007-05-08 2016-01-05 Hercules Incorporated Robust rapid disintegration tablet formulation
CN101322709B (zh) * 2007-06-12 2011-03-02 成都康弘药业集团股份有限公司 一种含有阿立哌唑的药物组合物及其制备方法
SG190618A1 (en) * 2008-05-02 2013-06-28 Gilead Sciences Inc The use of solid carrier particles to improve the processability of a pharmaceutical agent
JP5296456B2 (ja) * 2008-08-26 2013-09-25 大日本住友製薬株式会社 溶出が良好なイルベサルタン含有医薬組成物および口腔内崩壊錠
JP5594285B2 (ja) * 2009-03-16 2014-09-24 ニプロ株式会社 口腔内崩壊錠
WO2010146551A2 (en) * 2009-06-16 2010-12-23 Ranbaxy Laboratories Limited Orally disintegrating compositions comprising antihypertensive agents
CA2773003A1 (en) 2009-09-15 2011-03-24 Ratiopharm Gmbh Orally disintegrating pharmaceutical dosage form containing aripiprazole
TR201000689A1 (tr) * 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Sefprozil içeren katı dozaj formlar.
CN103284968B (zh) * 2010-04-13 2015-11-18 齐鲁制药有限公司 一种阿立哌唑组合物微晶的口腔崩解片及其制备方法
EP2384742A1 (en) 2010-05-03 2011-11-09 The Jordanian Pharmaceutical Manufacturing Co. Pharmaceutical excipient, method for its preparation and use thereof
DE102010019416A1 (de) * 2010-05-04 2011-11-10 Stada Arzneimittel Ag Schmelztablette, umfassend ein Triptan oder ein atypisches Neuroleptikum
HU1000278D0 (en) 2010-05-28 2010-07-28 Egis Gyogyszergyar Nyilvanosan Novel pharmaceutical use uf silicic acid
JP2012121850A (ja) * 2010-12-09 2012-06-28 Otsuka Pharmaceut Co Ltd アリピプラゾールの経口速溶性組成物
CN103561746B (zh) 2011-03-18 2018-05-29 奥克梅斯制药爱尔兰有限公司 包含脱水山梨糖醇酯的药物组合物
EP3854376A3 (en) * 2011-03-21 2021-12-22 Coloright Ltd. Systems for custom coloration
CN102846543B (zh) * 2011-06-27 2014-11-19 上海中西制药有限公司 一种阿立哌唑药物制剂及其制备方法
CN102846564B (zh) * 2011-06-28 2013-10-09 南京亿华药业有限公司 一种头孢丙烯片及其制法
CN102357086A (zh) * 2011-11-01 2012-02-22 上海理工大学 一种头孢丙烯口腔崩解片
AU2012360935A1 (en) * 2011-12-26 2014-07-17 Novartis Ag Tablets and dry-coated agents
CA2867123C (en) 2012-03-19 2021-02-16 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising water-insoluble antipsychotic agents and glycerol esters
EP2827868B8 (en) 2012-03-19 2019-12-18 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising fatty acid esters
CA2867137C (en) 2012-03-19 2020-12-08 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising aripiprazole prodrugs and benzyl alcohol
WO2013175508A2 (en) 2012-05-24 2013-11-28 Medreich Limited Stable pharmaceutical composition of aripiprazole
CA2779052A1 (en) * 2012-05-31 2013-11-30 Pharmascience Inc. Pharmaceutical composition of entecavir and process of manufacturing
KR101571670B1 (ko) 2012-08-08 2015-11-25 주식회사 씨엠지제약 아리피프라졸을 포함하는 경구용 속용 필름 제제
US20150224086A1 (en) * 2012-08-23 2015-08-13 Hetero Research Foundation Pharmaceutical Formulations of Rufinamide
CA2885196C (en) 2012-09-19 2021-06-22 Alkermes Pharma Ireland Limited Pharmaceutical compositions having improved storage stability
CN102885790B (zh) * 2012-09-20 2013-12-25 中国人民解放军第三〇二医院 恩替卡韦分散片及其制备方法
ES2625613T3 (es) 2013-04-30 2017-07-20 Otsuka Pharmaceutical Co., Ltd. Preparación sólida oral que comprende aripiprazol y método para producir una preparación sólida oral que comprende aripiprazol
JP5714652B2 (ja) * 2013-06-13 2015-05-07 大日本住友製薬株式会社 溶出が良好なイルベサルタン含有医薬組成物および口腔内崩壊錠
EP3065700A1 (en) 2013-11-07 2016-09-14 Synthon B.V. Orodispersible pharmaceutical compositions comprising aripiprazole
CN110368360A (zh) 2014-03-20 2019-10-25 奥克梅斯制药爱尔兰有限公司 具有增加的注射速度的阿立哌唑制剂
JP5978335B2 (ja) * 2015-03-11 2016-08-24 大日本住友製薬株式会社 溶出が良好なイルベサルタン含有医薬組成物および口腔内崩壊錠
KR20160139704A (ko) 2015-05-28 2016-12-07 주식회사 씨엠지제약 아리피프라졸을 포함하는 경구용 속용 필름 제제, 및 이의 제조방법
JP2015172084A (ja) * 2015-07-06 2015-10-01 大塚製薬株式会社 アリピプラゾールの経口速溶性組成物
US9855227B2 (en) 2015-12-18 2018-01-02 The Procter & Gamble Company Quick dissolving diphenhydramine oral dosage form
TR201617675A2 (tr) 2016-12-02 2018-06-21 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Ari̇pi̇prazole monohi̇drat formülasyonlarinin ağizda dağilan tablet formu
JP6572257B2 (ja) * 2017-05-16 2019-09-04 大塚製薬株式会社 アリピプラゾールの経口速溶性組成物
JP2017141299A (ja) * 2017-05-24 2017-08-17 大日本住友製薬株式会社 溶出が良好なイルベサルタン含有医薬組成物および口腔内崩壊錠
CN112423754A (zh) 2018-03-05 2021-02-26 奥克梅斯制药爱尔兰有限公司 阿立哌唑的给药策略
JP2018168185A (ja) * 2018-07-05 2018-11-01 大日本住友製薬株式会社 溶出が良好なイルベサルタン含有医薬組成物および口腔内崩壊錠
JP2019203031A (ja) * 2019-09-06 2019-11-28 大日本住友製薬株式会社 溶出が良好なイルベサルタン含有医薬組成物および口腔内崩壊錠
RU2732291C1 (ru) * 2020-02-13 2020-09-15 Открытое акционерное общество "Фармстандарт-Лексредства" (ОАО "Фармстандарт-Лексредства") Лекарственный препарат на основе травы алтея лекарственного для лечения простудных и острых респираторных заболеваний
GB2617603A (en) * 2022-04-13 2023-10-18 Univ Brunel Compositions for preventing and treating infection
CN115227661B (zh) * 2022-09-22 2022-12-13 北京惠之衡生物科技有限公司 一种利格列汀片及其制备方法

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1912354B2 (de) * 1969-03-12 1972-04-13 Reimbold & Strick, 5000 Köln-Kalk Synthetisches kristallines calciumsilikat und verfahren zu seiner herstellung
US3622677A (en) * 1969-07-07 1971-11-23 Staley Mfg Co A E Compressed tablets containing compacted starch as binder-disintegrant ingredient
FR2234244B1 (es) * 1973-06-20 1978-02-17 Rech Geolog Miniere
DE2556561C2 (de) 1975-12-16 1983-04-14 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Herstellung von porösen Tabletten
DE2845326C2 (de) * 1978-10-18 1985-05-23 Beiersdorf Ag, 2000 Hamburg Verwendung einer spezifischen mikrodispersen, amorphen, porösen Kieselsäure zur Herstellung von Digoxin enthaltenden Tabletten mit stark beschleunigter Wirkstoff-Freisetzung
DE2849494A1 (de) 1978-11-15 1980-05-29 Voss Gunter M Verfahren zur herstellung von arzneimittel-formlingen
US4327080A (en) * 1981-07-13 1982-04-27 E. R. Squibb & Sons, Inc. Novel Bendroflumethiazide formulations and method
ZA87279B (en) 1986-01-17 1987-09-30 Chugai Pharmaceutical Co Ltd Method for production of stable nicorandil preparation
AU7084587A (en) * 1986-04-01 1987-10-20 Upjohn Company, The Methylprednisolone/sodium carboxymethyl starch tablet composition
SE8601624D0 (sv) 1986-04-11 1986-04-11 Haessle Ab New pharmaceutical preparations
US5032552A (en) * 1988-07-04 1991-07-16 Tdk Corporation Biomedical material
US5006528A (en) * 1988-10-31 1991-04-09 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
US4906478A (en) * 1988-12-12 1990-03-06 Valentine Enterprises, Inc. Simethicone/calcium silicate composition
HU203041B (en) 1989-03-14 1991-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin
JPH06271744A (ja) * 1993-03-22 1994-09-27 Mizusawa Ind Chem Ltd ポリアセタール系樹脂用帯電防止剤
US5393472A (en) * 1993-06-30 1995-02-28 Shaw; John D. Method of producing wollastonite & ceramic bodies containing wollastonite
IL110376A (en) * 1993-08-02 1998-08-16 Bristol Myers Squibb Co Pharmaceutical preparations containing iftroban and methods for their preparation
AU7407194A (en) * 1993-08-03 1995-02-28 Warner-Lambert Company Pleasant tasting effervescent cold/allergy medications
US5622719A (en) * 1993-09-10 1997-04-22 Fuisz Technologies Ltd. Process and apparatus for making rapidly dissolving dosage units and product therefrom
US5895664A (en) * 1993-09-10 1999-04-20 Fuisz Technologies Ltd. Process for forming quickly dispersing comestible unit and product therefrom
US5994348A (en) * 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
TW442301B (en) * 1995-06-07 2001-06-23 Sanofi Synthelabo Pharmaceutical compositions containing irbesartan
WO1997019033A1 (en) * 1995-11-17 1997-05-29 Vrije Universiteit Brussel Inorganic resin compositions, their preparation and use thereof
TW430561B (en) * 1995-12-20 2001-04-21 Gea Farmaceutisk Fabrik As Rapid release tablet composition comprising tolfenamic acid or a pharmaceutically acceptable salt thereof as active ingredient and a method of preparing such tablet
DK1166651T3 (da) * 1996-02-29 2005-05-30 Fujisawa Pharmaceutical Co Hurtigt disintegrerende granulat af et syntetisk södemiddel indeholdende kiselsyre og/eller siliciumdioxid
GB9613470D0 (en) * 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
EP1380308B1 (en) * 1996-07-12 2008-07-09 Daiichi Pharmaceutical Co., Ltd. Quickly disintegrable compression-molded materials and process for producing the same
CA2258917A1 (en) * 1996-07-23 1998-01-29 Fmc Corporation Disintegrant composition for dispersible solids
JPH10114655A (ja) 1996-10-09 1998-05-06 Kyowa Hakko Kogyo Co Ltd 固形製剤
JPH10182436A (ja) 1996-10-31 1998-07-07 Takeda Chem Ind Ltd 固形医薬製剤
AUPO446397A0 (en) 1997-01-07 1997-01-30 Rees Equipment Pty Ltd Agricultural equipment direction control
US6024981A (en) * 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
TW527195B (en) * 1997-10-09 2003-04-11 Ssp Co Ltd Fast-soluble solid pharmaceutical combinations
JPH11152220A (ja) * 1997-11-19 1999-06-08 Daiichi Yakuhin Kogyo Kk 脂溶性薬物を含有した丸剤の製造方法
PL197989B1 (pl) * 1997-12-19 2008-05-30 Smithkline Beecham Corp Sposób wytwarzania szybko rozpraszających się tabletek do podawania doustnego, szybko rozpraszający się preparat farmaceutyczny w postaci tabletek i szybko rozpraszająca się, farmaceutycznie dopuszczalna, tabletka do podawania doustnego
US5914128A (en) * 1997-12-22 1999-06-22 Schering Corporation Orally administrable solid dosage form
EP1058538B9 (en) 1998-03-06 2013-01-02 Aptalis Pharma S.r.l. Fast disintegrating tablets
JP4027535B2 (ja) 1998-05-26 2007-12-26 エーザイ・アール・アンド・ディー・マネジメント株式会社 脂溶性薬物を含有した粉末
PE20000559A1 (es) * 1998-05-27 2000-07-05 Merck & Co Inc Formulacion de tabletas comprimidas de efavirenz
JP2000119014A (ja) 1998-08-12 2000-04-25 Fuji Chem Ind Co Ltd 無晶形ケイ酸アルミン酸カルシウム複合酸化物及びその製造方法並びに制酸剤
JP2000086537A (ja) 1998-09-11 2000-03-28 Fuji Chem Ind Co Ltd 無機化合物糖類組成物、賦形剤、速崩壊性圧縮成型物及びその製造方法
US6133378A (en) * 1998-11-20 2000-10-17 Bridgestone/Firestone, Inc. EPDM-based roofing shingle compositions
GB9914936D0 (en) 1999-06-26 1999-08-25 Cerestar Holding Bv Directly compressible starch as enhancer of properties of excipients when used as binder and disintegrant for compression tablets
US20020076437A1 (en) * 2000-04-12 2002-06-20 Sanjeev Kothari Flashmelt oral dosage formulation
CA2311734C (en) * 2000-04-12 2011-03-08 Bristol-Myers Squibb Company Flash-melt oral dosage formulation
WO2003003522A2 (en) 2001-06-29 2003-01-09 Xanoptix, Inc. High-precision female format multifiber connector
TWI324074B (en) * 2001-10-09 2010-05-01 Bristol Myers Squibb Co Flashmelt oral dosage formulation
US6610266B2 (en) * 2001-11-28 2003-08-26 Michael C. Withiam Calcium metasilicates and methods for making

Also Published As

Publication number Publication date
TR200001810A3 (tr) 2001-11-21
BR0003158A (pt) 2001-12-18
UY26306A1 (es) 2001-12-28
LT4896B (lt) 2002-02-25
SG108230A1 (en) 2005-01-28
ID29837A (id) 2001-10-18
TR200001810A2 (tr) 2001-11-21
BG104693A (en) 2002-02-28
IL136901A0 (en) 2001-06-14
HK1039572B (zh) 2007-01-12
AU752214B2 (en) 2002-09-12
EP1566174A3 (en) 2007-04-04
HUP0002316A3 (en) 2008-04-28
RO118563B1 (ro) 2003-07-30
US20130296337A1 (en) 2013-11-07
NZ505302A (en) 2001-12-21
PT1145711E (pt) 2006-11-30
LV12731A (en) 2001-10-20
CN100353933C (zh) 2007-12-12
US9358207B2 (en) 2016-06-07
KR20010096450A (ko) 2001-11-07
DK1145711T3 (da) 2006-10-02
MY125766A (en) 2006-08-30
ATE328584T1 (de) 2006-06-15
PL200409B1 (pl) 2009-01-30
SG117445A1 (en) 2005-12-29
CA2311734A1 (en) 2001-10-12
EE200000497A (et) 2001-12-17
CO5190672A1 (es) 2002-08-29
CZ20002391A3 (cs) 2001-11-14
US20110217342A1 (en) 2011-09-08
DE60028536D1 (de) 2006-07-20
EP1145711B1 (en) 2006-06-07
LV12731B (en) 2002-03-20
US8518421B2 (en) 2013-08-27
DE60028536T2 (de) 2007-05-16
KR100477293B1 (ko) 2005-03-17
SI20511A (sl) 2001-10-31
EP1566174A2 (en) 2005-08-24
HUP0002316A2 (hu) 2002-11-28
CN1317309A (zh) 2001-10-17
PE20010298A1 (es) 2001-05-20
IL136901A (en) 2008-03-20
EE04331B1 (et) 2004-08-16
NO20003196D0 (no) 2000-06-20
HK1039572A1 (en) 2002-05-03
JP2001302499A (ja) 2001-10-31
CA2311734C (en) 2011-03-08
HU0002316D0 (en) 2000-08-28
GEP20022851B (en) 2002-12-25
BG65007B1 (bg) 2006-12-29
NO20003196L (no) 2001-10-15
ES2265836T3 (es) 2007-03-01
EP1145711A1 (en) 2001-10-17
SK286368B6 (sk) 2008-08-05
EG23943A (en) 2008-01-22
SI20511B (sl) 2008-08-31
CY1105170T1 (el) 2010-03-03
PL341466A1 (en) 2001-10-22
SK9732000A3 (en) 2001-11-06
HU228864B1 (en) 2013-06-28
UA63993C2 (uk) 2004-02-16
IN188856B (es) 2002-11-16
NO330270B1 (no) 2011-03-14
LT2000064A (en) 2001-10-25
AU4373300A (en) 2001-10-18
TWI262799B (en) 2006-10-01
US20100016448A1 (en) 2010-01-21
ZA200003121B (en) 2001-12-21
RU2201216C2 (ru) 2003-03-27
JP3773763B2 (ja) 2006-05-10
CZ299145B6 (cs) 2008-04-30

Similar Documents

Publication Publication Date Title
AR024384A1 (es) UNA FORMA DE DOSIFICACIoN FARMACÉUTICA DE DISOLUCIoN INSTANTÁNEA Y UN MÉTODO PARA PREPARARLA
AR018143A1 (es) Formulacion para preparar un comprimido de desintegracion rapida, comprimidos de desintegracion rapida, especialmente comprimidos de desintegracionrapida en la boca
HUP0000976A2 (hu) Protonpumpa inhibitort tartalmazó, több egységből pezsgőtablettává préselt gyógyszeradagolási formák
NO993520L (no) Doseringsformer og fremgangsmÕte for Õ bedre erektil dysfunksjon
ECSP034869A (es) Una composicion para la piel, permeable selectiva inhibidora de ciclooxigenasa-2
ATE329579T1 (de) Feste dispersion mit ritonavir, fenofibrat oder griseofulvin
MX2008012731A (es) Tabletas de paracetamol de liberacion rapida.
MY127350A (en) Flash-melt oral dose formulations
MY127908A (en) Improved pharmaceutical formulations.
AR008820A1 (es) Comprimido dotado de recubrimiento laminar de maleato de trimebutina, destinado ala administracion por via oral, y un procedimiento para prepararlo
ATE460156T1 (de) Puffende orale darreichungsformen
NO20054417L (no) Fremgangsmate for fremstilling av farmasoytiske preperater i form av fibratholdige tabletter og de derved fremstilte tabletter
DK1227797T3 (da) Farmaceutiske faststofdispersionsformuleringer
HRP20000781B1 (en) Effervescent preparations
AR034435A1 (es) Agentes terapeuticos.
AR043412A1 (es) Formulaciones farmaceuticas que comprenden un agente enmascarante del sabor amargo
ATE266404T1 (de) Eine stabile pharmazeutische formulierung die torsemid modifikation ii enthält
DK1499278T3 (da) Farmaceutisk doseringsform, som udviser umiddelbar frigivelse, og som omfatter polymorf tibolon
PE20040040A1 (es) Unidades de dosificacion de progestagenico
TH32076A (th) รูปขนาดใช้ยาทางเภสัชกรรมสำหรับให้ทางปาก ซึ่งประกอบด้วยสารยับยั้งการดึงโปรตอน และสารโปรไคเนทิค
RS50500B (sr) Efervescentni farmaceutski proizvod derivata metilprednizolona i postupak za njegovo dobijanje
ECSP003607A (es) Formulaciones farmaceuticas en capsulas de hidroxipropilmetilcelulosa

Legal Events

Date Code Title Description
FG Grant, registration