ZA200005797B - Imidazo pyridine derivatives which inhibit gastric acid secretion. - Google Patents

Imidazo pyridine derivatives which inhibit gastric acid secretion. Download PDF

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Publication number
ZA200005797B
ZA200005797B ZA200005797A ZA200005797A ZA200005797B ZA 200005797 B ZA200005797 B ZA 200005797B ZA 200005797 A ZA200005797 A ZA 200005797A ZA 200005797 A ZA200005797 A ZA 200005797A ZA 200005797 B ZA200005797 B ZA 200005797B
Authority
ZA
South Africa
Prior art keywords
compound
formula
carboxamide
pyridine
dimethyl
Prior art date
Application number
ZA200005797A
Other languages
English (en)
Inventor
Kosrat Amin
Michael Dahlstroem
Peter Nordberg
Ingemar Starke
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ZA200005797B publication Critical patent/ZA200005797B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA200005797A 1998-04-29 2000-10-18 Imidazo pyridine derivatives which inhibit gastric acid secretion. ZA200005797B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9801526A SE9801526D0 (sv) 1998-04-29 1998-04-29 New compounds

Publications (1)

Publication Number Publication Date
ZA200005797B true ZA200005797B (en) 2002-01-18

Family

ID=20411154

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA200005796A ZA200005796B (en) 1998-04-29 2000-10-18 Imidazo pyridine derivatives which inhibit gastric acid secretion.
ZA200005797A ZA200005797B (en) 1998-04-29 2000-10-18 Imidazo pyridine derivatives which inhibit gastric acid secretion.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA200005796A ZA200005796B (en) 1998-04-29 2000-10-18 Imidazo pyridine derivatives which inhibit gastric acid secretion.

Country Status (34)

Country Link
US (2) US6313137B1 (ja)
EP (4) EP1491542B1 (ja)
JP (2) JP3692034B2 (ja)
KR (3) KR100650472B1 (ja)
CN (2) CN1174980C (ja)
AR (2) AR015768A1 (ja)
AT (4) ATE312101T1 (ja)
AU (2) AU769190B2 (ja)
BR (2) BR9909995B1 (ja)
CA (2) CA2329921A1 (ja)
CZ (2) CZ292567B6 (ja)
DE (4) DE69937076T2 (ja)
DK (2) DK1073657T3 (ja)
EE (2) EE04676B1 (ja)
ES (2) ES2252975T3 (ja)
HK (5) HK1033457A1 (ja)
HU (2) HUP0102313A3 (ja)
ID (2) ID27530A (ja)
IL (4) IL139200A0 (ja)
IS (2) IS5683A (ja)
MY (2) MY121389A (ja)
NO (2) NO318203B1 (ja)
NZ (2) NZ507638A (ja)
PL (2) PL195000B1 (ja)
RU (2) RU2238271C2 (ja)
SA (2) SA99200065B1 (ja)
SE (1) SE9801526D0 (ja)
SI (1) SI1073656T1 (ja)
SK (2) SK14912000A3 (ja)
TR (4) TR200102612T2 (ja)
TW (2) TWI250159B (ja)
UA (2) UA66846C2 (ja)
WO (2) WO1999055706A1 (ja)
ZA (2) ZA200005796B (ja)

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US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
US6900324B2 (en) 2000-09-07 2005-05-31 Astrazeneca Ab Process for preparing a substituted imidazopyridine compound
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0100295D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100297D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100296D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
NZ526993A (en) * 2001-02-13 2005-01-28 Astrazeneca Ab Pharmaceutical formulation of a drug substance that has a pH-dependent solubility in water
JP2004520422A (ja) * 2001-03-08 2004-07-08 アストラゼネカ・アクチエボラーグ 新しい用途
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
US6992080B2 (en) 2002-09-19 2006-01-31 Schering Corporation Imidazopyridines as cyclin dependent kinase inhibitors
JP2006508142A (ja) 2002-11-19 2006-03-09 アルタナ ファルマ アクチエンゲゼルシャフト 8−置換イミダゾピリジン
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
CN103265477B (zh) * 2003-02-26 2017-01-11 苏根公司 作为蛋白激酶抑制剂的氨基杂芳基化合物
PT1606261E (pt) 2003-03-10 2010-01-11 Nycomed Gmbh Novo processo para a preparação de roflumilast
SE525349C2 (sv) * 2003-06-23 2005-02-08 Volvo Penta Ab Utombordsdrev för båtar
SE0301904D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
SE0301903D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
SE0301905D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
EP1974730A1 (en) 2003-11-03 2008-10-01 AstraZeneca AB Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
US20080033006A1 (en) * 2004-01-26 2008-02-07 Altana Pharma Ag 1,2,4-Triazolo[ 1,5-A] Pyridines as Gastric Acid Secretion Inhibitors
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
AP2007004023A0 (en) * 2004-12-17 2007-06-30 Pfizer Chromane derivatives useful as acid pump antagonists
CA2601250C (en) 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
KR101300831B1 (ko) * 2005-03-21 2013-08-30 에스*바이오 피티이 리미티드 이미다조[1,2-a]피리딘 유도체, 이의 제조 방법 및 그의약학적 용도
TW200700064A (en) * 2005-03-24 2007-01-01 Glaxo Group Ltd Novel compounds
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
WO2007066185A2 (en) 2005-12-05 2007-06-14 Pfizer Products Inc. Polymorphs of a c-met/hgfr inhibitor
SI1959955T1 (sl) * 2005-12-05 2011-02-28 Pfizer Prod Inc Postopek zdravljenja abnormalne celične rasti
KR20080108129A (ko) * 2006-03-17 2008-12-11 라퀄리아 파마 인코포레이티드 크로메인 유도체
EP2054036B1 (en) 2006-07-24 2019-12-18 Singh-Broemer and Company, Inc. Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
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KR101777971B1 (ko) * 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
KR20190057569A (ko) * 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
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Also Published As

Publication number Publication date
CN1307577A (zh) 2001-08-08
CA2329922A1 (en) 1999-11-04
BR9909995A (pt) 2000-12-26
CZ292567B6 (cs) 2003-10-15
AU4300799A (en) 1999-11-16
TW490466B (en) 2002-06-11
EP1073656A1 (en) 2001-02-07
UA67769C2 (uk) 2004-07-15
BR9909995B1 (pt) 2010-07-13
CZ293977B6 (cs) 2004-09-15
HUP0102313A2 (hu) 2001-12-28
DE69937077T2 (de) 2008-05-29
KR100595806B1 (ko) 2006-07-03
TR200102728T2 (tr) 2002-06-21
DE69927803D1 (de) 2006-03-02
AR015768A1 (es) 2001-05-16
JP2002513024A (ja) 2002-05-08
DE69928792D1 (de) 2006-01-12
NO20005450D0 (no) 2000-10-27
TR200102612T2 (tr) 2002-06-21
TWI250159B (en) 2006-03-01
SE9801526D0 (sv) 1998-04-29
JP2002513025A (ja) 2002-05-08
NZ507639A (en) 2004-01-30
TR200003149T2 (tr) 2001-03-21
CA2329922C (en) 2006-04-11
AU769108B2 (en) 2004-01-15
HK1071139A1 (en) 2005-07-08
CZ20003982A3 (cs) 2001-02-14
AR015769A1 (es) 2001-05-16
EE04676B1 (et) 2006-08-15
PL195000B1 (pl) 2007-07-31
HK1033317A1 (en) 2001-08-24
HUP0102425A2 (hu) 2001-11-28
IL139200A (en) 2010-04-29
KR100595805B1 (ko) 2006-07-03
SA99200064B1 (ar) 2006-10-11
WO1999055706A9 (en) 2000-03-16
KR20010043133A (ko) 2001-05-25
ATE312101T1 (de) 2005-12-15
US6313136B1 (en) 2001-11-06
ES2249913T3 (es) 2006-04-01
RU2238271C2 (ru) 2004-10-20
JP3692034B2 (ja) 2005-09-07
DE69937076T2 (de) 2008-05-29
CN1174980C (zh) 2004-11-10
IL139200A0 (en) 2001-11-25
DK1073656T3 (da) 2006-01-16
AU769190B2 (en) 2004-01-22
PL343797A1 (en) 2001-09-10
HK1033457A1 (en) 2001-08-31
KR100650472B1 (ko) 2006-11-28
CZ20003981A3 (cs) 2001-03-14
ATE372340T1 (de) 2007-09-15
DE69937077D1 (de) 2007-10-18
TR200003176T2 (tr) 2001-03-21
HUP0102313A3 (en) 2002-10-28
CN1306533A (zh) 2001-08-01
HUP0102425A3 (en) 2002-12-28
DE69927803T2 (de) 2006-07-06
EP1491543A1 (en) 2004-12-29
EP1073657A1 (en) 2001-02-07
MY121389A (en) 2006-01-28
JP3883383B2 (ja) 2007-02-21
IS5684A (is) 2000-10-25
EE200000664A (et) 2002-04-15
EP1491542B1 (en) 2007-09-05
BR9909996B1 (pt) 2010-08-24
SI1073656T1 (sl) 2006-02-28
WO1999055706A1 (en) 1999-11-04
HK1036981A1 (en) 2002-01-25
UA66846C2 (uk) 2004-06-15
PL343801A1 (en) 2001-09-10
NO20005451D0 (no) 2000-10-27
ES2252975T3 (es) 2006-05-16
IL139297A (en) 2007-06-03
HK1036984A1 (en) 2002-01-25
US6313137B1 (en) 2001-11-06
WO1999055705A1 (en) 1999-11-04
NO20005450L (no) 2000-12-22
KR20050121760A (ko) 2005-12-27
NO317262B1 (no) 2004-09-27
ATE307130T1 (de) 2005-11-15
KR20010043134A (ko) 2001-05-25
NZ507638A (en) 2003-10-31
EP1073657B1 (en) 2005-12-07
ID27530A (id) 2001-04-12
SK14912000A3 (sk) 2001-06-11
CN1165535C (zh) 2004-09-08
ID26819A (id) 2001-02-15
SA99200065B1 (ar) 2006-11-07
SK14922000A3 (sk) 2001-06-11
BR9909996A (pt) 2000-12-26
EE04916B1 (et) 2007-10-15
ZA200005796B (en) 2002-01-18
EE200000626A (et) 2002-04-15
SK285768B6 (sk) 2007-07-06
NO20005451L (no) 2000-12-27
AU4300699A (en) 1999-11-16
EP1073656B1 (en) 2005-10-19
CA2329921A1 (en) 1999-11-04
SA99200065A (ar) 2005-12-03
EP1491543B1 (en) 2007-09-05
ATE372339T1 (de) 2007-09-15
NO318203B1 (no) 2005-02-14
EP1491542A3 (en) 2005-01-05
IL139297A0 (en) 2001-11-25
IS5683A (is) 2000-10-25
MY121379A (en) 2006-01-28
DE69928792T2 (de) 2006-07-20
DE69937076D1 (de) 2007-10-18
DK1073657T3 (da) 2006-03-13
RU2235725C2 (ru) 2004-09-10
EP1491542A2 (en) 2004-12-29

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